CN105126048B - The Chinese materia medica preparation and its production method for preventing and treating sheep parasitic disease - Google Patents
The Chinese materia medica preparation and its production method for preventing and treating sheep parasitic disease Download PDFInfo
- Publication number
- CN105126048B CN105126048B CN201510529412.9A CN201510529412A CN105126048B CN 105126048 B CN105126048 B CN 105126048B CN 201510529412 A CN201510529412 A CN 201510529412A CN 105126048 B CN105126048 B CN 105126048B
- Authority
- CN
- China
- Prior art keywords
- parts
- sheep
- materia medica
- chinese materia
- medica preparation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 241001494479 Pecora Species 0.000 title claims abstract description 60
- 238000002360 preparation method Methods 0.000 title claims abstract description 34
- 239000002398 materia medica Substances 0.000 title claims abstract description 32
- 208000030852 Parasitic disease Diseases 0.000 title claims abstract description 29
- 238000004519 manufacturing process Methods 0.000 title claims abstract description 21
- 235000006886 Zingiber officinale Nutrition 0.000 claims abstract description 34
- 235000008397 ginger Nutrition 0.000 claims abstract description 34
- 240000002234 Allium sativum Species 0.000 claims abstract description 25
- 235000004611 garlic Nutrition 0.000 claims abstract description 24
- 244000247747 Coptis groenlandica Species 0.000 claims abstract description 20
- 235000002991 Coptis groenlandica Nutrition 0.000 claims abstract description 20
- 241001504477 Pycnonotidae Species 0.000 claims abstract description 16
- 239000002994 raw material Substances 0.000 claims abstract description 11
- 230000002265 prevention Effects 0.000 claims abstract description 10
- 241000234314 Zingiber Species 0.000 claims description 30
- 239000003814 drug Substances 0.000 claims description 17
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 8
- 235000014360 Punica granatum Nutrition 0.000 claims description 6
- 239000000843 powder Substances 0.000 claims description 6
- 239000012530 fluid Substances 0.000 claims description 3
- 238000001802 infusion Methods 0.000 claims description 3
- 238000003756 stirring Methods 0.000 claims description 3
- 244000294611 Punica granatum Species 0.000 claims 1
- 239000004575 stone Substances 0.000 claims 1
- 230000000694 effects Effects 0.000 abstract description 17
- 108010034145 Helminth Proteins Proteins 0.000 abstract description 15
- 244000000013 helminth Species 0.000 abstract description 15
- 201000010099 disease Diseases 0.000 abstract description 10
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract description 10
- 208000002720 Malnutrition Diseases 0.000 abstract description 5
- 244000273928 Zingiber officinale Species 0.000 abstract description 5
- 230000007423 decrease Effects 0.000 abstract description 5
- 230000001071 malnutrition Effects 0.000 abstract description 5
- 235000000824 malnutrition Nutrition 0.000 abstract description 5
- 208000015380 nutritional deficiency disease Diseases 0.000 abstract description 5
- 230000004596 appetite loss Effects 0.000 abstract description 4
- 235000021266 loss of appetite Nutrition 0.000 abstract description 4
- 208000019017 loss of appetite Diseases 0.000 abstract description 4
- 231100000331 toxic Toxicity 0.000 abstract description 2
- 230000002588 toxic effect Effects 0.000 abstract description 2
- 239000000796 flavoring agent Substances 0.000 description 8
- 235000019634 flavors Nutrition 0.000 description 8
- 241000196324 Embryophyta Species 0.000 description 7
- 241000219991 Lythraceae Species 0.000 description 7
- 239000008280 blood Substances 0.000 description 7
- 210000004369 blood Anatomy 0.000 description 7
- 210000000936 intestine Anatomy 0.000 description 7
- 244000045947 parasite Species 0.000 description 7
- 210000002784 stomach Anatomy 0.000 description 7
- WITLAWYGGVAFLU-UHFFFAOYSA-N 3-(6-methoxy-1,3-benzodioxol-5-yl)-8,8-dimethylpyrano[2,3-f]chromen-4-one Chemical compound C1=CC(C)(C)OC2=CC=C(C(C(C3=CC=4OCOC=4C=C3OC)=CO3)=O)C3=C21 WITLAWYGGVAFLU-UHFFFAOYSA-N 0.000 description 6
- 229940079593 drug Drugs 0.000 description 5
- 208000001848 dysentery Diseases 0.000 description 5
- 206010062717 Increased upper airway secretion Diseases 0.000 description 4
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 description 4
- AUNGANRZJHBGPY-SCRDCRAPSA-N Riboflavin Chemical compound OC[C@@H](O)[C@@H](O)[C@@H](O)CN1C=2C=C(C)C(C)=CC=2N=C2C1=NC(=O)NC2=O AUNGANRZJHBGPY-SCRDCRAPSA-N 0.000 description 4
- 239000002253 acid Substances 0.000 description 4
- PTOJXIKSKSASRB-UHFFFAOYSA-O candicine Chemical compound C[N+](C)(C)CCC1=CC=C(O)C=C1 PTOJXIKSKSASRB-UHFFFAOYSA-O 0.000 description 4
- 239000013043 chemical agent Substances 0.000 description 4
- 235000011389 fruit/vegetable juice Nutrition 0.000 description 4
- 230000002496 gastric effect Effects 0.000 description 4
- 210000004209 hair Anatomy 0.000 description 4
- 208000026435 phlegm Diseases 0.000 description 4
- 208000004998 Abdominal Pain Diseases 0.000 description 3
- JDLKFOPOAOFWQN-VIFPVBQESA-N Allicin Natural products C=CCS[S@](=O)CC=C JDLKFOPOAOFWQN-VIFPVBQESA-N 0.000 description 3
- UNHHWEHQUUGKEE-MLLLWRCASA-N Amurensin Chemical compound C1=C(O)C(C(C(O)=C(O2)C=3C=CC(O)=CC=3)=O)=C2C(CCC(C)(O)C)=C1O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O UNHHWEHQUUGKEE-MLLLWRCASA-N 0.000 description 3
- HDQHRTXBXYQUNW-CABCVRRESA-N Amurensine Natural products O(C)c1c(O)cc2[C@H]3c4c(cc5OCOc5c4)C[C@H](N(C)C3)c2c1 HDQHRTXBXYQUNW-CABCVRRESA-N 0.000 description 3
- 241000193830 Bacillus <bacterium> Species 0.000 description 3
- 206010011224 Cough Diseases 0.000 description 3
- 206010012735 Diarrhoea Diseases 0.000 description 3
- 241000244206 Nematoda Species 0.000 description 3
- 206010037660 Pyrexia Diseases 0.000 description 3
- 208000025865 Ulcer Diseases 0.000 description 3
- 206010047700 Vomiting Diseases 0.000 description 3
- JDLKFOPOAOFWQN-UHFFFAOYSA-N allicin Chemical compound C=CCSS(=O)CC=C JDLKFOPOAOFWQN-UHFFFAOYSA-N 0.000 description 3
- 235000010081 allicin Nutrition 0.000 description 3
- UNHHWEHQUUGKEE-UHFFFAOYSA-N amurensin Natural products C1=C(O)C(C(C(O)=C(O2)C=3C=CC(O)=CC=3)=O)=C2C(CCC(C)(O)C)=C1OC1OC(CO)C(O)C(O)C1O UNHHWEHQUUGKEE-UHFFFAOYSA-N 0.000 description 3
- 230000000202 analgesic effect Effects 0.000 description 3
- 230000003110 anti-inflammatory effect Effects 0.000 description 3
- 230000036528 appetite Effects 0.000 description 3
- 235000019789 appetite Nutrition 0.000 description 3
- 239000003795 chemical substances by application Substances 0.000 description 3
- 230000006378 damage Effects 0.000 description 3
- FJSOHLNMRNSYFR-OPDZODGYSA-N epimedoside C Natural products O([C@H]1[C@H](O)[C@@H](O)[C@@H](O)[C@@H](CO)O1)c1c(C/C=C(\C)/C)c2OC(c3ccc(O)cc3)=C(O)C(=O)c2c(O)c1 FJSOHLNMRNSYFR-OPDZODGYSA-N 0.000 description 3
- 208000006275 fascioliasis Diseases 0.000 description 3
- RAXXELZNTBOGNW-UHFFFAOYSA-N imidazole Natural products C1=CNC=N1 RAXXELZNTBOGNW-UHFFFAOYSA-N 0.000 description 3
- 239000004615 ingredient Substances 0.000 description 3
- 230000005764 inhibitory process Effects 0.000 description 3
- 210000004185 liver Anatomy 0.000 description 3
- 210000004072 lung Anatomy 0.000 description 3
- 238000000034 method Methods 0.000 description 3
- 230000035922 thirst Effects 0.000 description 3
- 239000003053 toxin Substances 0.000 description 3
- 231100000765 toxin Toxicity 0.000 description 3
- 231100000397 ulcer Toxicity 0.000 description 3
- 239000000341 volatile oil Substances 0.000 description 3
- 230000008673 vomiting Effects 0.000 description 3
- 206010063409 Acarodermatitis Diseases 0.000 description 2
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 description 2
- 206010007247 Carbuncle Diseases 0.000 description 2
- 241001478240 Coccus Species 0.000 description 2
- AUNGANRZJHBGPY-UHFFFAOYSA-N D-Lyxoflavin Natural products OCC(O)C(O)C(O)CN1C=2C=C(C)C(C)=CC=2N=C2C1=NC(=O)NC2=O AUNGANRZJHBGPY-UHFFFAOYSA-N 0.000 description 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 2
- 241000233866 Fungi Species 0.000 description 2
- 206010017553 Furuncle Diseases 0.000 description 2
- MXTLAHSTUOXGQF-UHFFFAOYSA-O Jatrorrhizine Chemical compound COC1=CC=C2C=C3C(C=C(C(=C4)O)OC)=C4CC[N+]3=CC2=C1OC MXTLAHSTUOXGQF-UHFFFAOYSA-O 0.000 description 2
- 206010023126 Jaundice Diseases 0.000 description 2
- PVNIIMVLHYAWGP-UHFFFAOYSA-N Niacin Chemical compound OC(=O)C1=CC=CN=C1 PVNIIMVLHYAWGP-UHFFFAOYSA-N 0.000 description 2
- 208000002193 Pain Diseases 0.000 description 2
- BQLZQPGWNVTIHR-UHFFFAOYSA-N Phellavin Natural products C1=C2OC(C=3C=CC(O)=CC=3)=C(O)C(=O)C2=C(O)C(CCC(C)(O)C)=C1OC1OC(CO)C(O)C(O)C1O BQLZQPGWNVTIHR-UHFFFAOYSA-N 0.000 description 2
- RBBVPNQTBKHOEQ-KKSFZXQISA-O Phellodendrine Chemical compound C1CC2=CC(OC)=C(O)C=C2[C@H]2[N@+]1(C)CC(C=C(C(=C1)O)OC)=C1C2 RBBVPNQTBKHOEQ-KKSFZXQISA-O 0.000 description 2
- 240000000111 Saccharum officinarum Species 0.000 description 2
- 235000007201 Saccharum officinarum Nutrition 0.000 description 2
- 241000447727 Scabies Species 0.000 description 2
- 241000191967 Staphylococcus aureus Species 0.000 description 2
- 241000191963 Staphylococcus epidermidis Species 0.000 description 2
- 206010044565 Tremor Diseases 0.000 description 2
- 241000700605 Viruses Species 0.000 description 2
- 206010052428 Wound Diseases 0.000 description 2
- 208000027418 Wounds and injury Diseases 0.000 description 2
- 210000001015 abdomen Anatomy 0.000 description 2
- 238000004458 analytical method Methods 0.000 description 2
- 230000000507 anthelmentic effect Effects 0.000 description 2
- 230000000844 anti-bacterial effect Effects 0.000 description 2
- 230000001062 anti-nausea Effects 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 2
- 230000008901 benefit Effects 0.000 description 2
- LGJMUZUPVCAVPU-UHFFFAOYSA-N beta-Sitostanol Natural products C1CC2CC(O)CCC2(C)C2C1C1CCC(C(C)CCC(CC)C(C)C)C1(C)CC2 LGJMUZUPVCAVPU-UHFFFAOYSA-N 0.000 description 2
- 239000007844 bleaching agent Substances 0.000 description 2
- 150000001720 carbohydrates Chemical class 0.000 description 2
- 235000014633 carbohydrates Nutrition 0.000 description 2
- 235000009508 confectionery Nutrition 0.000 description 2
- 239000003651 drinking water Substances 0.000 description 2
- 235000020188 drinking water Nutrition 0.000 description 2
- 230000005284 excitation Effects 0.000 description 2
- 230000004438 eyesight Effects 0.000 description 2
- 208000035861 hematochezia Diseases 0.000 description 2
- 230000023597 hemostasis Effects 0.000 description 2
- 241000411851 herbal medicine Species 0.000 description 2
- 235000012907 honey Nutrition 0.000 description 2
- 229910052742 iron Inorganic materials 0.000 description 2
- 230000002147 killing effect Effects 0.000 description 2
- 230000007774 longterm Effects 0.000 description 2
- 235000013372 meat Nutrition 0.000 description 2
- 235000001968 nicotinic acid Nutrition 0.000 description 2
- 239000011664 nicotinic acid Substances 0.000 description 2
- 229960003512 nicotinic acid Drugs 0.000 description 2
- 231100000252 nontoxic Toxicity 0.000 description 2
- 230000003000 nontoxic effect Effects 0.000 description 2
- 235000016709 nutrition Nutrition 0.000 description 2
- 230000001717 pathogenic effect Effects 0.000 description 2
- RNYZJZKPGHQTJR-UHFFFAOYSA-N protoanemonin Chemical compound C=C1OC(=O)C=C1 RNYZJZKPGHQTJR-UHFFFAOYSA-N 0.000 description 2
- 210000002345 respiratory system Anatomy 0.000 description 2
- 235000019192 riboflavin Nutrition 0.000 description 2
- 239000002151 riboflavin Substances 0.000 description 2
- 229960002477 riboflavin Drugs 0.000 description 2
- 208000005687 scabies Diseases 0.000 description 2
- 210000000952 spleen Anatomy 0.000 description 2
- 230000001954 sterilising effect Effects 0.000 description 2
- 238000004659 sterilization and disinfection Methods 0.000 description 2
- -1 sulfide compound Chemical class 0.000 description 2
- 239000013589 supplement Substances 0.000 description 2
- 239000001841 zingiber officinale Substances 0.000 description 2
- OILXMJHPFNGGTO-UHFFFAOYSA-N (22E)-(24xi)-24-methylcholesta-5,22-dien-3beta-ol Natural products C1C=C2CC(O)CCC2(C)C2C1C1CCC(C(C)C=CC(C)C(C)C)C1(C)CC2 OILXMJHPFNGGTO-UHFFFAOYSA-N 0.000 description 1
- YLRXAIKMLINXQY-ZDUSSCGKSA-O (S)-magnoflorine Chemical compound C1=C(OC)C(O)=C2C3=C(O)C(OC)=CC=C3C[C@@H]3[N+](C)(C)CCC1=C23 YLRXAIKMLINXQY-ZDUSSCGKSA-O 0.000 description 1
- BJEPYKJPYRNKOW-REOHCLBHSA-N (S)-malic acid Chemical compound OC(=O)[C@@H](O)CC(O)=O BJEPYKJPYRNKOW-REOHCLBHSA-N 0.000 description 1
- 125000003903 2-propenyl group Chemical group [H]C([*])([H])C([H])=C([H])[H] 0.000 description 1
- AZSNMRSAGSSBNP-UHFFFAOYSA-N 22,23-dihydroavermectin B1a Natural products C1CC(C)C(C(C)CC)OC21OC(CC=C(C)C(OC1OC(C)C(OC3OC(C)C(O)C(OC)C3)C(OC)C1)C(C)C=CC=C1C3(C(C(=O)O4)C=C(C)C(O)C3OC1)O)CC4C2 AZSNMRSAGSSBNP-UHFFFAOYSA-N 0.000 description 1
- YXACCHLOUSCDDR-UHFFFAOYSA-N 3,5-dihydroxy-6-(3-hydroxy-3-methylbutyl)-2-(4-hydroxyphenyl)-7-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-2,3-dihydrochromen-4-one Chemical compound CC(C)(O)CCC1=C(O)C=2C(=O)C(O)C(C=3C=CC(O)=CC=3)OC=2C=C1OC1OC(CO)C(O)C(O)C1O YXACCHLOUSCDDR-UHFFFAOYSA-N 0.000 description 1
- QGJZLNKBHJESQX-UHFFFAOYSA-N 3-Epi-Betulin-Saeure Natural products C1CC(O)C(C)(C)C2CCC3(C)C4(C)CCC5(C(O)=O)CCC(C(=C)C)C5C4CCC3C21C QGJZLNKBHJESQX-UHFFFAOYSA-N 0.000 description 1
- OQMZNAMGEHIHNN-UHFFFAOYSA-N 7-Dehydrostigmasterol Natural products C1C(O)CCC2(C)C(CCC3(C(C(C)C=CC(CC)C(C)C)CCC33)C)C3=CC=C21 OQMZNAMGEHIHNN-UHFFFAOYSA-N 0.000 description 1
- SPBDXSGPUHCETR-JFUDTMANSA-N 8883yp2r6d Chemical compound O1[C@@H](C)[C@H](O)[C@@H](OC)C[C@@H]1O[C@@H]1[C@@H](OC)C[C@H](O[C@@H]2C(=C/C[C@@H]3C[C@@H](C[C@@]4(O[C@@H]([C@@H](C)CC4)C(C)C)O3)OC(=O)[C@@H]3C=C(C)[C@@H](O)[C@H]4OC\C([C@@]34O)=C/C=C/[C@@H]2C)/C)O[C@H]1C.C1C[C@H](C)[C@@H]([C@@H](C)CC)O[C@@]21O[C@H](C\C=C(C)\[C@@H](O[C@@H]1O[C@@H](C)[C@H](O[C@@H]3O[C@@H](C)[C@H](O)[C@@H](OC)C3)[C@@H](OC)C1)[C@@H](C)\C=C\C=C/1[C@]3([C@H](C(=O)O4)C=C(C)[C@@H](O)[C@H]3OC\1)O)C[C@H]4C2 SPBDXSGPUHCETR-JFUDTMANSA-N 0.000 description 1
- 239000005660 Abamectin Substances 0.000 description 1
- 206010000060 Abdominal distension Diseases 0.000 description 1
- 241000251468 Actinopterygii Species 0.000 description 1
- XUHLIQGRKRUKPH-GCXOYZPQSA-N Alliin Natural products N[C@H](C[S@@](=O)CC=C)C(O)=O XUHLIQGRKRUKPH-GCXOYZPQSA-N 0.000 description 1
- 244000016163 Allium sibiricum Species 0.000 description 1
- 235000001270 Allium sibiricum Nutrition 0.000 description 1
- 239000004251 Ammonium lactate Substances 0.000 description 1
- 206010002199 Anaphylactic shock Diseases 0.000 description 1
- JLUQTCXCAFSSLD-NXEZZACHSA-N Anemonin Chemical compound C1=CC(=O)O[C@]11[C@@]2(C=CC(=O)O2)CC1 JLUQTCXCAFSSLD-NXEZZACHSA-N 0.000 description 1
- JLUQTCXCAFSSLD-UHFFFAOYSA-N Anemonin Natural products C1=CC(=O)OC11C2(C=CC(=O)O2)CC1 JLUQTCXCAFSSLD-UHFFFAOYSA-N 0.000 description 1
- 241000283690 Bos taurus Species 0.000 description 1
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 description 1
- SGNBVLSWZMBQTH-FGAXOLDCSA-N Campesterol Natural products O[C@@H]1CC=2[C@@](C)([C@@H]3[C@H]([C@H]4[C@@](C)([C@H]([C@H](CC[C@H](C(C)C)C)C)CC4)CC3)CC=2)CC1 SGNBVLSWZMBQTH-FGAXOLDCSA-N 0.000 description 1
- VYZAMTAEIAYCRO-UHFFFAOYSA-N Chromium Chemical compound [Cr] VYZAMTAEIAYCRO-UHFFFAOYSA-N 0.000 description 1
- WTEVQBCEXWBHNA-UHFFFAOYSA-N Citral Natural products CC(C)=CCCC(C)=CC=O WTEVQBCEXWBHNA-UHFFFAOYSA-N 0.000 description 1
- 244000089795 Clausena lansium Species 0.000 description 1
- 235000008738 Clausena lansium Nutrition 0.000 description 1
- 241000037740 Coptis chinensis Species 0.000 description 1
- 240000009087 Crescentia cujete Species 0.000 description 1
- 235000005983 Crescentia cujete Nutrition 0.000 description 1
- ZZZCUOFIHGPKAK-UHFFFAOYSA-N D-erythro-ascorbic acid Natural products OCC1OC(=O)C(O)=C1O ZZZCUOFIHGPKAK-UHFFFAOYSA-N 0.000 description 1
- 201000004624 Dermatitis Diseases 0.000 description 1
- 206010013954 Dysphoria Diseases 0.000 description 1
- 208000000059 Dyspnea Diseases 0.000 description 1
- 206010013975 Dyspnoeas Diseases 0.000 description 1
- 241001151130 Eilema Species 0.000 description 1
- 241000282326 Felis catus Species 0.000 description 1
- 108010028690 Fish Proteins Proteins 0.000 description 1
- 208000012671 Gastrointestinal haemorrhages Diseases 0.000 description 1
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 1
- 108010043121 Green Fluorescent Proteins Proteins 0.000 description 1
- 208000034507 Haematemesis Diseases 0.000 description 1
- BTEISVKTSQLKST-UHFFFAOYSA-N Haliclonasterol Natural products CC(C=CC(C)C(C)(C)C)C1CCC2C3=CC=C4CC(O)CCC4(C)C3CCC12C BTEISVKTSQLKST-UHFFFAOYSA-N 0.000 description 1
- 206010019233 Headaches Diseases 0.000 description 1
- 208000000616 Hemoptysis Diseases 0.000 description 1
- 208000009889 Herpes Simplex Diseases 0.000 description 1
- OVSQVDMCBVZWGM-SJWGPRHPSA-N Hyperin Natural products O[C@H]1[C@H](O)[C@@H](O)[C@@H](CO)O[C@H]1OC1=C(C=2C=C(O)C(O)=CC=2)OC2=CC(O)=CC(O)=C2C1=O OVSQVDMCBVZWGM-SJWGPRHPSA-N 0.000 description 1
- FVQOMEDMFUMIMO-UHFFFAOYSA-N Hyperosid Natural products OC1C(O)C(O)C(CO)OC1OC1C(=O)C2=C(O)C=C(O)C=C2OC1C1=CC=C(O)C(O)=C1 FVQOMEDMFUMIMO-UHFFFAOYSA-N 0.000 description 1
- 206010020772 Hypertension Diseases 0.000 description 1
- 208000015817 Infant Nutrition disease Diseases 0.000 description 1
- 206010023138 Jaundice neonatal Diseases 0.000 description 1
- 235000009797 Lagenaria vulgaris Nutrition 0.000 description 1
- 235000019687 Lamb Nutrition 0.000 description 1
- KYEAXNAYHSCLMT-CVVGWEDFSA-N Magnoflorine Natural products C[C@H]1OC=C2[C@@H]3[C@@H]1CN4CCc5c([nH]c6ccccc56)[C@@H]4[C@@H]3OC2=O KYEAXNAYHSCLMT-CVVGWEDFSA-N 0.000 description 1
- 241001465754 Metazoa Species 0.000 description 1
- 206010027514 Metrorrhagia Diseases 0.000 description 1
- 206010028748 Nasal obstruction Diseases 0.000 description 1
- 201000006346 Neonatal Jaundice Diseases 0.000 description 1
- 206010028980 Neoplasm Diseases 0.000 description 1
- IOVCWXUNBOPUCH-UHFFFAOYSA-N Nitrous acid Chemical compound ON=O IOVCWXUNBOPUCH-UHFFFAOYSA-N 0.000 description 1
- 206010030113 Oedema Diseases 0.000 description 1
- 241000283903 Ovis aries Species 0.000 description 1
- PTPHDVKWAYIFRX-UHFFFAOYSA-N Palmatine Natural products C1C2=C(OC)C(OC)=CC=C2C=C2N1CCC1=C2C=C(OC)C(OC)=C1 PTPHDVKWAYIFRX-UHFFFAOYSA-N 0.000 description 1
- 241000935974 Paralichthys dentatus Species 0.000 description 1
- 201000005702 Pertussis Diseases 0.000 description 1
- BQLZQPGWNVTIHR-AWGWVDLJSA-N Phellatin Chemical compound C1=C2OC(C=3C=CC(O)=CC=3)=C(O)C(=O)C2=C(O)C(CCC(C)(O)C)=C1O[C@@H]1OC(CO)[C@@H](O)[C@H](O)C1O BQLZQPGWNVTIHR-AWGWVDLJSA-N 0.000 description 1
- 241001079007 Phellodendron chinense Species 0.000 description 1
- OAICVXFJPJFONN-UHFFFAOYSA-N Phosphorus Chemical compound [P] OAICVXFJPJFONN-UHFFFAOYSA-N 0.000 description 1
- 241001522129 Pinellia Species 0.000 description 1
- 206010035664 Pneumonia Diseases 0.000 description 1
- 208000004880 Polyuria Diseases 0.000 description 1
- 241000589517 Pseudomonas aeruginosa Species 0.000 description 1
- 241000219780 Pueraria Species 0.000 description 1
- 241000123887 Pulsatilla chinensis Species 0.000 description 1
- 206010061926 Purulence Diseases 0.000 description 1
- 241000218201 Ranunculaceae Species 0.000 description 1
- 206010067171 Regurgitation Diseases 0.000 description 1
- 241001093501 Rutaceae Species 0.000 description 1
- XUHLIQGRKRUKPH-UHFFFAOYSA-N S-allyl-L-cysteine sulfoxide Natural products OC(=O)C(N)CS(=O)CC=C XUHLIQGRKRUKPH-UHFFFAOYSA-N 0.000 description 1
- 241000207929 Scutellaria Species 0.000 description 1
- 240000004534 Scutellaria baicalensis Species 0.000 description 1
- 235000017089 Scutellaria baicalensis Nutrition 0.000 description 1
- BUGBHKTXTAQXES-UHFFFAOYSA-N Selenium Chemical compound [Se] BUGBHKTXTAQXES-UHFFFAOYSA-N 0.000 description 1
- 241000607760 Shigella sonnei Species 0.000 description 1
- 208000013738 Sleep Initiation and Maintenance disease Diseases 0.000 description 1
- 206010041497 Spermatorrhoea Diseases 0.000 description 1
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 description 1
- 229930006000 Sucrose Natural products 0.000 description 1
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 description 1
- 241000254223 Syntexis Species 0.000 description 1
- 244000223014 Syzygium aromaticum Species 0.000 description 1
- 235000016639 Syzygium aromaticum Nutrition 0.000 description 1
- 244000269722 Thea sinensis Species 0.000 description 1
- JZRWCGZRTZMZEH-UHFFFAOYSA-N Thiamine Natural products CC1=C(CCO)SC=[N+]1CC1=CN=C(C)N=C1N JZRWCGZRTZMZEH-UHFFFAOYSA-N 0.000 description 1
- 208000007536 Thrombosis Diseases 0.000 description 1
- 241000130764 Tinea Species 0.000 description 1
- 208000002474 Tinea Diseases 0.000 description 1
- 208000037386 Typhoid Diseases 0.000 description 1
- HZYXFRGVBOPPNZ-UHFFFAOYSA-N UNPD88870 Natural products C1C=C2CC(O)CCC2(C)C2C1C1CCC(C(C)=CCC(CC)C(C)C)C1(C)CC2 HZYXFRGVBOPPNZ-UHFFFAOYSA-N 0.000 description 1
- 208000003443 Unconsciousness Diseases 0.000 description 1
- 208000024780 Urticaria Diseases 0.000 description 1
- 229930003268 Vitamin C Natural products 0.000 description 1
- HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 description 1
- 240000008866 Ziziphus nummularia Species 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 239000003513 alkali Substances 0.000 description 1
- 229930013930 alkaloid Natural products 0.000 description 1
- XUHLIQGRKRUKPH-DYEAUMGKSA-N alliin Chemical compound OC(=O)[C@@H](N)C[S@@](=O)CC=C XUHLIQGRKRUKPH-DYEAUMGKSA-N 0.000 description 1
- 235000015295 alliin Nutrition 0.000 description 1
- BJEPYKJPYRNKOW-UHFFFAOYSA-N alpha-hydroxysuccinic acid Natural products OC(=O)C(O)CC(O)=O BJEPYKJPYRNKOW-UHFFFAOYSA-N 0.000 description 1
- 229940059265 ammonium lactate Drugs 0.000 description 1
- 235000019286 ammonium lactate Nutrition 0.000 description 1
- 208000003455 anaphylaxis Diseases 0.000 description 1
- 208000007502 anemia Diseases 0.000 description 1
- 230000002804 anti-anaphylactic effect Effects 0.000 description 1
- 239000000729 antidote Substances 0.000 description 1
- 239000002246 antineoplastic agent Substances 0.000 description 1
- 229940041181 antineoplastic drug Drugs 0.000 description 1
- 208000002399 aphthous stomatitis Diseases 0.000 description 1
- 230000001174 ascending effect Effects 0.000 description 1
- 208000010668 atopic eczema Diseases 0.000 description 1
- RRZXIRBKKLTSOM-XPNPUAGNSA-N avermectin B1a Chemical compound C1=C[C@H](C)[C@@H]([C@@H](C)CC)O[C@]11O[C@H](C\C=C(C)\[C@@H](O[C@@H]2O[C@@H](C)[C@H](O[C@@H]3O[C@@H](C)[C@H](O)[C@@H](OC)C3)[C@@H](OC)C2)[C@@H](C)\C=C\C=C/2[C@]3([C@H](C(=O)O4)C=C(C)[C@@H](O)[C@H]3OC\2)O)C[C@H]4C1 RRZXIRBKKLTSOM-XPNPUAGNSA-N 0.000 description 1
- RZOBLYBZQXQGFY-HSHFZTNMSA-N azanium;(2r)-2-hydroxypropanoate Chemical compound [NH4+].C[C@@H](O)C([O-])=O RZOBLYBZQXQGFY-HSHFZTNMSA-N 0.000 description 1
- 150000003851 azoles Chemical class 0.000 description 1
- 239000002585 base Substances 0.000 description 1
- 230000003796 beauty Effects 0.000 description 1
- 229940076810 beta sitosterol Drugs 0.000 description 1
- NJKOMDUNNDKEAI-UHFFFAOYSA-N beta-sitosterol Natural products CCC(CCC(C)C1CCC2(C)C3CC=C4CC(O)CCC4C3CCC12C)C(C)C NJKOMDUNNDKEAI-UHFFFAOYSA-N 0.000 description 1
- QXMNTPFFZFYQAI-IMDKZJJXSA-N beta-sitosterol 3-O-beta-D-glucopyranoside Natural products CC[C@H](CC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@H](CC[C@]4(C)[C@H]3CC[C@]12C)O[C@@H]5C[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O)C(C)C QXMNTPFFZFYQAI-IMDKZJJXSA-N 0.000 description 1
- QGJZLNKBHJESQX-FZFNOLFKSA-N betulinic acid Chemical compound C1C[C@H](O)C(C)(C)[C@@H]2CC[C@@]3(C)[C@]4(C)CC[C@@]5(C(O)=O)CC[C@@H](C(=C)C)[C@@H]5[C@H]4CC[C@@H]3[C@]21C QGJZLNKBHJESQX-FZFNOLFKSA-N 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 230000000903 blocking effect Effects 0.000 description 1
- 230000017531 blood circulation Effects 0.000 description 1
- 208000027503 bloody stool Diseases 0.000 description 1
- 238000009835 boiling Methods 0.000 description 1
- 210000000988 bone and bone Anatomy 0.000 description 1
- 239000011575 calcium Substances 0.000 description 1
- 229910052791 calcium Inorganic materials 0.000 description 1
- 235000000431 campesterol Nutrition 0.000 description 1
- SGNBVLSWZMBQTH-PODYLUTMSA-N campesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CC[C@@H](C)C(C)C)[C@@]1(C)CC2 SGNBVLSWZMBQTH-PODYLUTMSA-N 0.000 description 1
- 230000005907 cancer growth Effects 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 238000002512 chemotherapy Methods 0.000 description 1
- 230000001055 chewing effect Effects 0.000 description 1
- 229910052804 chromium Inorganic materials 0.000 description 1
- 239000011651 chromium Substances 0.000 description 1
- 208000019902 chronic diarrheal disease Diseases 0.000 description 1
- 230000004087 circulation Effects 0.000 description 1
- 229940043350 citral Drugs 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- NPJICTMALKLTFW-OFUAXYCQSA-N daucosterol Chemical compound O([C@@H]1CC2=CC[C@H]3[C@@H]4CC[C@@H]([C@]4(CC[C@@H]3[C@@]2(C)CC1)C)[C@H](C)CC[C@@H](CC)C(C)C)[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O NPJICTMALKLTFW-OFUAXYCQSA-N 0.000 description 1
- QDFKFNAHVGPRBL-UHFFFAOYSA-N daucosterol Natural products CCC(CCC(C)C1CCC2C1CCC3C2(C)CC=C4CC(CCC34C)OC5OC(CO)C(O)C(O)C5O)C(C)C QDFKFNAHVGPRBL-UHFFFAOYSA-N 0.000 description 1
- 238000006356 dehydrogenation reaction Methods 0.000 description 1
- 238000001784 detoxification Methods 0.000 description 1
- 230000035487 diastolic blood pressure Effects 0.000 description 1
- 230000029087 digestion Effects 0.000 description 1
- 230000001079 digestive effect Effects 0.000 description 1
- 210000002249 digestive system Anatomy 0.000 description 1
- 230000035619 diuresis Effects 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 210000000613 ear canal Anatomy 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 208000001780 epistaxis Diseases 0.000 description 1
- 230000003628 erosive effect Effects 0.000 description 1
- 230000004907 flux Effects 0.000 description 1
- 208000003512 furunculosis Diseases 0.000 description 1
- 210000000232 gallbladder Anatomy 0.000 description 1
- 210000004051 gastric juice Anatomy 0.000 description 1
- 239000010437 gem Substances 0.000 description 1
- 229910001751 gemstone Inorganic materials 0.000 description 1
- 230000002068 genetic effect Effects 0.000 description 1
- WTEVQBCEXWBHNA-JXMROGBWSA-N geranial Chemical compound CC(C)=CCC\C(C)=C\C=O WTEVQBCEXWBHNA-JXMROGBWSA-N 0.000 description 1
- 229910052732 germanium Inorganic materials 0.000 description 1
- GNPVGFCGXDBREM-UHFFFAOYSA-N germanium atom Chemical compound [Ge] GNPVGFCGXDBREM-UHFFFAOYSA-N 0.000 description 1
- 229940002508 ginger extract Drugs 0.000 description 1
- 235000020708 ginger extract Nutrition 0.000 description 1
- 210000003128 head Anatomy 0.000 description 1
- 231100000869 headache Toxicity 0.000 description 1
- 230000035876 healing Effects 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 208000021760 high fever Diseases 0.000 description 1
- 230000007062 hydrolysis Effects 0.000 description 1
- 238000006460 hydrolysis reaction Methods 0.000 description 1
- 208000013403 hyperactivity Diseases 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 230000001939 inductive effect Effects 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 230000008595 infiltration Effects 0.000 description 1
- 238000001764 infiltration Methods 0.000 description 1
- 230000002401 inhibitory effect Effects 0.000 description 1
- 206010022437 insomnia Diseases 0.000 description 1
- 244000000053 intestinal parasite Species 0.000 description 1
- 229960002418 ivermectin Drugs 0.000 description 1
- 210000002429 large intestine Anatomy 0.000 description 1
- 238000002386 leaching Methods 0.000 description 1
- 244000144972 livestock Species 0.000 description 1
- 235000011090 malic acid Nutrition 0.000 description 1
- 239000001630 malic acid Substances 0.000 description 1
- 230000003211 malignant effect Effects 0.000 description 1
- WPBNNNQJVZRUHP-UHFFFAOYSA-L manganese(2+);methyl n-[[2-(methoxycarbonylcarbamothioylamino)phenyl]carbamothioyl]carbamate;n-[2-(sulfidocarbothioylamino)ethyl]carbamodithioate Chemical compound [Mn+2].[S-]C(=S)NCCNC([S-])=S.COC(=O)NC(=S)NC1=CC=CC=C1NC(=S)NC(=O)OC WPBNNNQJVZRUHP-UHFFFAOYSA-L 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 description 1
- 238000002156 mixing Methods 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 210000004400 mucous membrane Anatomy 0.000 description 1
- 210000003205 muscle Anatomy 0.000 description 1
- 208000011309 nasal bleeding Diseases 0.000 description 1
- 238000007034 nitrosation reaction Methods 0.000 description 1
- 235000015097 nutrients Nutrition 0.000 description 1
- 230000035764 nutrition Effects 0.000 description 1
- 239000003921 oil Substances 0.000 description 1
- 210000000056 organ Anatomy 0.000 description 1
- QUCQEUCGKKTEBI-UHFFFAOYSA-N palmatine Chemical compound COC1=CC=C2C=C(C3=C(C=C(C(=C3)OC)OC)CC3)[N+]3=CC2=C1OC QUCQEUCGKKTEBI-UHFFFAOYSA-N 0.000 description 1
- 230000024241 parasitism Effects 0.000 description 1
- 230000000144 pharmacologic effect Effects 0.000 description 1
- 229910052698 phosphorus Inorganic materials 0.000 description 1
- 239000011574 phosphorus Substances 0.000 description 1
- 231100000614 poison Toxicity 0.000 description 1
- 231100000572 poisoning Toxicity 0.000 description 1
- 230000000607 poisoning effect Effects 0.000 description 1
- 244000144977 poultry Species 0.000 description 1
- 239000002244 precipitate Substances 0.000 description 1
- 125000001436 propyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
- 239000011241 protective layer Substances 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 238000010926 purge Methods 0.000 description 1
- 238000010791 quenching Methods 0.000 description 1
- OVSQVDMCBVZWGM-DTGCRPNFSA-N quercetin 3-O-beta-D-galactopyranoside Chemical compound O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@H]1OC1=C(C=2C=C(O)C(O)=CC=2)OC2=CC(O)=CC(O)=C2C1=O OVSQVDMCBVZWGM-DTGCRPNFSA-N 0.000 description 1
- BBFYUPYFXSSMNV-UHFFFAOYSA-N quercetin-7-o-galactoside Natural products OC1C(O)C(O)C(CO)OC1OC1=CC(O)=C2C(=O)C(O)=C(C=3C=C(O)C(O)=CC=3)OC2=C1 BBFYUPYFXSSMNV-UHFFFAOYSA-N 0.000 description 1
- KKOXKGNSUHTUBV-UHFFFAOYSA-N racemic zingiberene Natural products CC(C)=CCCC(C)C1CC=C(C)C=C1 KKOXKGNSUHTUBV-UHFFFAOYSA-N 0.000 description 1
- 201000010727 rectal prolapse Diseases 0.000 description 1
- 238000007670 refining Methods 0.000 description 1
- 210000001034 respiratory center Anatomy 0.000 description 1
- 238000007665 sagging Methods 0.000 description 1
- 229910052711 selenium Inorganic materials 0.000 description 1
- 239000011669 selenium Substances 0.000 description 1
- 229910052709 silver Inorganic materials 0.000 description 1
- 239000004332 silver Substances 0.000 description 1
- KZJWDPNRJALLNS-VJSFXXLFSA-N sitosterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CC[C@@H](CC)C(C)C)[C@@]1(C)CC2 KZJWDPNRJALLNS-VJSFXXLFSA-N 0.000 description 1
- 229950005143 sitosterol Drugs 0.000 description 1
- 210000000813 small intestine Anatomy 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- HCXVJBMSMIARIN-PHZDYDNGSA-N stigmasterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)/C=C/[C@@H](CC)C(C)C)[C@@]1(C)CC2 HCXVJBMSMIARIN-PHZDYDNGSA-N 0.000 description 1
- 235000016831 stigmasterol Nutrition 0.000 description 1
- 229940032091 stigmasterol Drugs 0.000 description 1
- BFDNMXAIBMJLBB-UHFFFAOYSA-N stigmasterol Natural products CCC(C=CC(C)C1CCCC2C3CC=C4CC(O)CCC4(C)C3CCC12C)C(C)C BFDNMXAIBMJLBB-UHFFFAOYSA-N 0.000 description 1
- 230000000638 stimulation Effects 0.000 description 1
- 238000007920 subcutaneous administration Methods 0.000 description 1
- 229910052717 sulfur Inorganic materials 0.000 description 1
- 239000011593 sulfur Substances 0.000 description 1
- 210000004243 sweat Anatomy 0.000 description 1
- 230000008961 swelling Effects 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 238000003786 synthesis reaction Methods 0.000 description 1
- 230000035488 systolic blood pressure Effects 0.000 description 1
- 150000003505 terpenes Chemical class 0.000 description 1
- 235000007586 terpenes Nutrition 0.000 description 1
- 235000019157 thiamine Nutrition 0.000 description 1
- KYMBYSLLVAOCFI-UHFFFAOYSA-N thiamine Chemical compound CC1=C(CCO)SCN1CC1=CN=C(C)N=C1N KYMBYSLLVAOCFI-UHFFFAOYSA-N 0.000 description 1
- 229960003495 thiamine Drugs 0.000 description 1
- 239000011721 thiamine Substances 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
- 208000004371 toothache Diseases 0.000 description 1
- 239000003440 toxic substance Substances 0.000 description 1
- 201000008297 typhoid fever Diseases 0.000 description 1
- 230000001457 vasomotor Effects 0.000 description 1
- 210000001835 viscera Anatomy 0.000 description 1
- 235000019154 vitamin C Nutrition 0.000 description 1
- 239000011718 vitamin C Substances 0.000 description 1
- 239000011800 void material Substances 0.000 description 1
- 238000010792 warming Methods 0.000 description 1
- 210000002268 wool Anatomy 0.000 description 1
- 230000029663 wound healing Effects 0.000 description 1
- 239000011701 zinc Substances 0.000 description 1
- 229910052725 zinc Inorganic materials 0.000 description 1
- KKOXKGNSUHTUBV-LSDHHAIUSA-N zingiberene Chemical compound CC(C)=CCC[C@H](C)[C@H]1CC=C(C)C=C1 KKOXKGNSUHTUBV-LSDHHAIUSA-N 0.000 description 1
- 229930001895 zingiberene Natural products 0.000 description 1
- 150000004622 zingiberene derivatives Chemical class 0.000 description 1
Landscapes
- Medicines Containing Plant Substances (AREA)
Abstract
The invention discloses a kind of Chinese materia medica preparations and its production method for preventing and treating sheep parasitic disease, it is characterised in that: the raw material including following parts by weight: 20-30 parts of Cortex Phellodendri, 20-30 parts of the coptis, 20-30 parts of radix scutellariae, 5-10 parts of ginger, 5-10 parts of the Chinese bulbul, 2-4 parts of granatum, 2-4 parts of garlic, 0.5-1.0 parts of brown sugar.The Chinese materia medica preparation of prevention and treatment sheep parasitic disease of the invention can not only prevent, drive away or kill the intracorporal helminth of sheep, moreover it is possible to treat the diseases such as loss of appetite, production performance decline and the malnutrition that sheep suffers from by helminth；And the present invention prevents and treats the Chinese materia medica preparation of sheep parasitic disease and passes through scientific compatibility, to the disease that sheep helminth causes have good curative effect, have no toxic side effect, cheap, production is simple.
Description
Technical field
It is the present invention relates to Chinese herbal medicine preparation technology field, in particular to a kind of dedicated in prevention and treatment sheep parasitic disease
Medicine preparation and its production method.
Background technique
Sheep is China first class of protection place livestock and poultry species, has precocity, four seasons heat, 1 year tire, the more lambs of every tire, secretes
Milkiness energy is good, growth and development is fast, has the merits such as ideal meat production, high-temp resisting high-humidity resisting after improvement.1~2 day postpartum government official stripping
Chekiang lamb skin decorative pattern it is beautiful, be world-famous for.The main Taihu Lake basin between Zhejiang, Jiangsu in producing region, so being known as " sheep ".Lake
Sheep is rare white lambskin sheep variety, has meat production good, and the merits such as high-temp resisting high-humidity resisting killed the small of stripping in postpartum 1~2 day
Taihu Sheep Skin decorative pattern is beautiful, is known as the laudatory title of " the soft jewel in east " in overseas market.Sheep physique is medium, and constitution is solid, acerous, head
Long and narrow, bridge of the nose protuberance, neck is elongated, and body body is long and narrow, and back waist is straight, and abdomen is micro- sagging, and tail is oblate, and tail point upwarps, and four limbs are partially thin and high,
Belly wool is sparse, short and thick." national Genetic Resources of Domestic Animal protection mesh has successively been put by the Ministry of Agriculture twice at 2000 and 2006
Record ".
Sheep parasitic disease can occur throughout the year, serious with spring and autumn harm.Sheep parasitic disease mainly has liver
Fascioliasis, metenteron line parasitosis, gastrointestinal nematode parasites.Helminth mainly causes the machinery of organ, tissue to the harm of sheep
Property damage, capture nutrition or generate toxin, decline sheep syntexis, anaemia, malnutrition, production performance, serious person can lead to extremely
It dies.
The traditional treatment method of sheep parasitic disease is all using azoles of rattling away in rosickyite imidazole, avermectin, ivermectin, beauty
Chemical agents are waited to drive away sheep helminth.But drives away sheep helminth using chemical agent and be not easy to grasp dosage, medicament
It is excessively poisoned, anthelminthic effect is not enough not achieved in pharmaceutical quantities；And chemical agent side effect is very big, is taken throughout the year to sheep
Generate multiple complications.
Summary of the invention
A kind of Chinese medicine system for preventing and treating sheep parasitic disease is provided the purpose of the present invention is insufficient for the above-mentioned prior art
Agent and its production method, the Chinese materia medica preparation can not only prevent, drive away or kill the intracorporal helminth of sheep, moreover it is possible to treat sheep because
Helminth and loss of appetite, production performance decline and the diseases such as malnutrition suffered from；And the present invention prevents and treats sheep parasitism
The Chinese materia medica preparation of parasitosis passes through scientific compatibility, has good curative effect to the disease that sheep helminth causes, has no toxic side effect, valence
Lattice are cheap, production is simple.
Realization that the present invention adopts the following technical solutions:
The present invention prevents and treats the Chinese materia medica preparation of sheep parasitic disease, the raw material including following parts by weight:
20-30 parts of Cortex Phellodendri, 20-30 parts of the coptis, 20-30 parts of radix scutellariae, 5-10 parts of ginger, 5-10 parts of the Chinese bulbul, pomegranate
2-4 parts of skin, 2-4 parts of garlic, 0.5-1.0 parts of brown sugar.
Above-described Chinese materia medica preparation, the raw material including following parts by weight: 25 parts of Cortex Phellodendri, 25 parts of the coptis, 25 parts of radix scutellariae,
6 parts of ginger, 6 parts of the Chinese bulbul, 3 parts of granatum, 3 parts of garlic, 0.6 part of brown sugar.
The present invention is made of Chinese medicinal materials such as Cortex Phellodendri, the coptis, radix scutellariae, ginger, the Chinese bulbul, granatum and garlics, is had clear
The effect of thermal detoxification whets the appetite, anti-inflammatory analgetic, sterilization, desinsection, expelling parasite, can prevent, drives away or kill the helminth of sheep
And the diseases such as loss of appetite, production performance decline and malnutrition that sheep suffers from by helminth can also be treated.
Each medicine effective ingredient analysis of the Chinese materia medica preparation Chinese medicine preparation of above-described prevention and treatment sheep parasitic disease:
Cortex Phellodendri, [alias] CORTEX PHELLODENDRI CHINENSE, [Latin literary fame]Phellodendron chinense Schneid.. For Rutaceae
The bark of plant Cortex Phellodendri or wampee is distributed in the ground such as Southern Shaanxi, Zhejiang, Jiangxi, Hubei, Sichuan, Guizhou, Yunnan, Guangxi.
[nature and flavor] are sweet, tremble with fear.Cortex Phellodendri contains jamaicin, jateorrhizine, magnoflorine, phellodendrine, candicine, palmatine, bat
The alkaloids such as bat Pueraria lobota alkali;Separately containing obakunone, obakulactone, Dictamnolide, obacunonic acid, green fluorescent acid, 7- dehydrogenation stigmasterol, β-
Sitosterol, campesterol.Root skin contains jamaicin, jateorrhizine, phellodendrine, candicine.Timber also contains jamaicin.It is fresh
Leaf contains amurensin, amurensin, phellatin, phellavin.Dried leaf contains hyperin, is free of amurensin.To controlling
Treating sheep parasitic disease has significant effect.1. supplement to the Herbal: main herpes simplex blister rises, worm sore, dysentery, and lower blood kills moth；Decoction,
Master quenches one's thirst." 2. Japan hanako materia medica ": feeling at ease to control hectic fever due to yin except labor, wash liver, improving eyesight, more tears, dry, the heart is warm, kills infantile malnutrition due to digestive disturbances or intestinalparasites worm, controls the ascarid heart
Bitterly, profuse nasal bleeding is controlled in scabies, honey toast, and intestines wind rushes down blood, rear point of anxious heat swelling and pain.
The coptis, [alias] coptis, river company, Jiang Lian, RHIZOMA COPTIDIS from Sichuan of China, prepared RHIZOMA COPTIDIS with rhizoma zingiberis recens juice, RHIZOMA COPTIDIS from Sichuan of China, the ginger coptis, cornel company, cornel coptis,
Stir-bake to yellowish company etc.；[Latin]Coptis chinensis Franch.；Herbaceos perennial belongs to hair in place of happiness cools, is wet
Liang section Coptis, is distributed in the ground such as Sichuan, Guizhou, Hunan, Hubei, Southern Shaanxi.[nature and flavor] are bitter, tremble with fear.[major function] heat-clearing
Eliminating dampness, purging fire for removing toxin.For damp and hot feeling of fullness, acid regurgitation, dysentery, jaundice, unconsciousness due to high fever, heart-fire hyperactivity, dysphoria and insomnia, blood-head are vomitted
Hematemesis, hot eyes, toothache are quenched one's thirst, carbuncle swells furunculosis；Eczema, wet sore, purulent ear canal are controlled outside.1. Shennong's Herbal: bitter is trembled with fear.It is main
Hot gas, mesh pain are controlled, corner of the eyes wound is wept out, improving eyesight, intestines Bleach, abdominal pain, diarrhea, is swollen and ache in married woman's yin.Long term usage makes us not forgetting.2. " book on Chinese herbal medicine spreads out
Justice ": moderns are multi-purpose to control dysentery, and lid is held with bitter dry justice.Under it is valgar but see intestines void infiltration let out, it is micro- seemingly to there is bloody stool not know more to stop that is, with it.
Fever and chills are ignored again how much, but be degree with most agent, by being that more cause danger are tired.If the real just disease of gas, the more bloody flux of heat, just stopping for clothes still need not
Agent to the greatest extent.Or it is empty and cold, then it is not necessary to take.It is remaining such as " warp "." 3. Kaibao Bencao ": bitter, it is slightly cold, it is nontoxic.The five internal organs are cold and hot, let out under long
Bleach, purulence blood, only quench one's thirst, frightened, remove water conservancy bone, adjust stomach, thick intestines, and beneficial gallbladder treats aphtha.
Scutellaria, [alias] Radix Scutellariae, tsuchikane tea root；[Latin]Scutellaria baicalensis Georgi,It is more
Year raw herbaceous plant；It is distributed in the ground such as Hebei, Liaoning, Shaanxi, Shandong, the Inner Mongol, Heilungkiang；[nature and flavor] bitter, gas is flat, property
It is cold；[major function] cures mainly warm heat disease, the infection of the upper respiratory tract, cough with lung heat, neonatal jaundice caused by dampness-heat, pneumonia, dysentery, hemoptysis, hot eyes, tire
The diseases such as dynamic uneasiness, hypertension, carbuncle swells furuncle sore." 1. detailed outline ": Shennong's Herbal: main all hot jaundice, intestines are out-of-the-way, let out benefit, relieve oedema or abdominal distension through diuresis or purgation, and lower blood closes,
(controlling) malignant sore, subcutaneous ulcer erosion, fiery ulcer.2. " Bie Lu ": treating phlegm heat, pathogenic heat in the stomach, small eilema, disappear paddy, and sharp small intestine, woman's blood closes, leaching dew
Lower blood, abdominal pain in children." 3. medicine origin ": radix scutellariae is in harmony damp and hot in lung, swells in hot mesh in treatment red, and hemostasis ridge is contained, must with medicine.
Fire ascending abnormally to the upper is let out in lung in every upper, the cold never foot of wing all of a sudden is mended, is growing its change source.
Ginger, [alias] race, Bailayun, another name for ginger, hook finger, because ground is pungent, cool kid, fresh ginger, fried ginger with honey, ginger peel, ginger
Silver, Bailayun, another name for ginger；[Latin]Zingiber officinale Roscoe. ；It is Zingiber herbaceos perennial ginger(Zingiber officinale Roscoe)Fresh rhizome；Flavor efficacy: pungent, tepor.Can whet the appetite preventing or arresting vomiting, preventing phlegm from forming and stopping coughing,
Inducing sweat and dispelling exogenous evils, warming middle energizer to arrest vomiting, solving toxin of fish and crab solve poisoning of drug.Pharmacological action 1, the effect to digestive system: ginger is treatment hydrochloric acid-
The active drug of alcohol repellency ulcer, effective component are zingiberene, have the function of protecting Gastric Mucosal Cells in fragrant stomach invigorating crude drug
In, it is one of raw the effective elements of the medicine of stomach invigorating mostly containing terpenes derived essential oils such as zingiberenes especially in zingiberaceous plant.2, to circulation
The effect of system and respiratory system: ginger alcohol extracting thing has excitation to anesthetized cat vasomotor center and respiratory center, right
Heart also has direct excitation.Normal person's chewing ginger 1g(is not swallowed), systolic pressure can be made averagely to increase 1.489 kPa
(11.2mmHg), diastolic pressure rise 1.862kPa(14mmHg), pulse frequency is then had no significant effect.3, resisting pathogenic microbes makees
With: ginger extract has staphylococcus aureus, staphylococcus albus, typhoid bacillus, bacterium sonnei, Pseudomonas aeruginosa
Obvious inhibiting effect, effect are in dependence with concentration.Especially made with the inhibition of staphylococcus aureus and staphylococcus albus
With most by force.4, other are acted on: ginger mud and ginger leachate have apparent facilitation ginger juice can be one wound healing
Determine to inhibit growth of cancer cells that Ginger P.E is added in some anti-tumor drugs in degree that the secondary work of tumour medicine can be mitigated
With.Ginger has obvious blocking effect to nitrosation reaction under the conditions of simulate the gastric juice, inhibits the effective component of nitrous acid synthesis
To thermostabilization, after heating the long duration in boiling water, still keep quite strongly active.Ginger P.E has antianaphylactic medicine
Effect, can prevent anaphylactic shock, prevent nettle rash caused by certain fish proteins." 1. Mingyi Bielu ": acrid flavour, tepor.It is main
Control cold headache, nasal obstruction, cough with dyspnea, anti-nausea.Also, ginger, tepor is pungent, Gui Wuzang.Phlegm, lower gas are removed, anti-nausea removes wind
Evil fever and chills.The small will of long term usage lacks intelligence, sad gas.2. supplement to the Herbal: outside this function, juice antidote goes cold from remaining blood-breaking, tune, removes
Phlegm, appetizing.It hot must remove the peel, cold and stay skin." 3. drug property cerse ": acrid flavour, it is warm-natured, it is nontoxic.It rises, sun.It is with having four: system
The tuber of pinellia has the function of removing toxic substances, and assistant jujube has saying for thick intestines.Temperature stops the sound of vomiting that stomach turns over through dissipating the wind of table heresy, QI invigorating.
The Chinese bulbul, [latin name]Pulsatilla chinensis (Bunge) Regel.,Ranunculaceae plant, it is perennial
Draft, Chinese bulbul bitter are cold in nature；Return stomach, large intestine channel, have clearing heat and detoxicating, removes heat from the blood and relieve diarrhea, the effect of removing dampness and destroying parasites.The Chinese bulbul
Root contains anemoside, A, B, C, D, 3-O- α-L- rhamnopyranose--3 β of (1 → 2)-α-L- arabopyranose, 23- dihydroxy
Base-△ 20(29)-lupene -28- acid, anemoside, Daucosterol, betulic acid, Anemonin, protoanemonin, it is right
Preventing and treating sheep parasitic disease has significant effect.
Granatum, [alias] pomegranate shell, sour pomegranate skin, sour pomegranate skin, [latin name]Pomegranate Rind, it is Punicaceae
The pericarp of plant pomegranate, in China, most area is all distributed, and is a kind of plant of resource very abundant；[nature and flavor] are sour and astringent,
Temperature, [major function] puckery intestines, hemostasis, expelling parasite；Control chronic diarrhea, protracted dysentery, hematochezia, rectal prolapse, spermatorrhoea, metrorrhagia and metrostaxis, leukorrhagia, abdominal pain due to enterositosis, scabies
Tinea.Granatum decoction has anthelmintic effect.Its mechanism system acts on the muscle of helminth, it is made to sink into contracts last, and has and drive
The benefits of worm.In addition, granatum after the contact such as they and mucous membrane, the surface of a wound, can precipitate or solidify local albumen containing matter of mixing is contained more
Matter makes to form comparatively dense protective layer on surface, facilitates local woanded surface healing or protects part from stimulation.
Garlic, [alias] garlic, garlic, giant garlic, calabash, only garlic, single clove garlic；It is the general designation of garlic class plant, half a year sward
This plant.[latin name]Allium sativum L.Garlic nutrient is abundant: every 69.8 grams of 100 grams of moisture contents, 4.4 grams of protein,
0.2 gram, 23.6 grams of carbohydrate, 5 milligrams of calcium, 44 milligrams of phosphorus, 0.4 milligram of iron, 3 milligrams of vitamin C of fat.In addition, also containing
There are the microelements such as thiamine, riboflavin, niacin, allicin, citral and selenium and germanium.It is main in oil containing volatile oil about 0.2%
Wanting ingredient is allicin, has bactericidal effect, is that alliin contained in garlic is generated by the effect hydrolysis of big allinase；Also contain
A variety of allyls, propyl and sulfide compound of methyl composition etc..Sulfur-containing compound is made with stronger antibacterial anti-inflammatory in garlic
With having inhibition and killing effect to a variety of coccuses, bacillus, fungi and virus etc..Modern studies have found that the volatile oil of garlic,
Juice, leachate and allicin are to a variety of coccuses, bacillus (such as pertussis), mould, fungi (such as crypotococcal), virus etc.
There are inhibition and killing effect.
Brown sugar is that sugarcane is raw material, and raw sugar made of the techniques such as stove drying, nondiscoloration, brown sugar are needed not move through after juicing
It is warm, sweet in flavor, enter spleen, have the function of blood-enrich, invigorating the spleen warm stomach, it is slow in analgesic, activate blood circulation and disperse blood clots.It is protected without the brown sugar of refining
The nutritional ingredient for having stayed more sugarcane is also more easier to be absorbed by AMMONIUM LACTATE ON DIGESTION, therefore can quickly regain one's strength of body, enhance vigour,
Wherein not only containing the carbohydrate that can provide thermal energy, also contain malic acid, riboflavin, carrotene, niacin and microelement
The various elements such as manganese, zinc, chromium.According to analysis, 90 milligrams of every 100 grams of brown sugar calcic is 3 times of white sugar；4 milligrams of iron content, be white
3 times of sugar.
The production method of above-mentioned Chinese materia medica preparation is: in parts by weight by dry Cortex Phellodendri, the coptis, radix scutellariae, ginger, hoary hair
Father-in-law, granatum and garlic are ground into 100-120 targeted fine powder；Medicinal powder is poured into extractor, water is added and impregnates 20-30 points
Clock is added 5-8 times that water is medicine gross weight, 90-100 DEG C of infusion 1-1.5 hours is then heated to, to fluid temperature
Brown sugar is added when being down to 30 DEG C -50 DEG C, stirring is filtered to get the Chinese materia medica preparation of prevention and treatment sheep parasitic disease.
The usage of Chinese materia medica preparation of the present invention: Chinese materia medica preparation of the invention is watered and is taken to sheep；This hair of 50ml is taken every time
Bright Chinese materia medica preparation, is blended into the drinking water of sheep, takes 1-3 times daily.
The beneficial effects of the present invention are:
1, Chinese materia medica preparation of the present invention is using herbaceous plant such as Cortex Phellodendri, the coptis, radix scutellariae, ginger, the Chinese bulbul, granatum and garlics
It refines, Cortex Phellodendri, the coptis, radix scutellariae, ginger, the Chinese bulbul, granatum and garlic are without side-effects, and abundant raw materials are easy to get, production
Process is simple, at low cost.
2, the Chinese materia medica preparation of present invention prevention and treatment sheep parasitic disease passes through scientific compatibility, is only capable of prevention, drives away or kill lake
The intracorporal helminth of sheep, moreover it is possible to treat loss of appetite, production performance decline and malnutrition that sheep suffers from by helminth
Etc. diseases；Short treating period, it is quick, do not use chemical agent, cure rate reaches 95% or more；With clearing heat and detoxicating, whet the appetite,
The effect of anti-inflammatory analgetic, sterilization, desinsection, expelling parasite.
Specific embodiment
Embodiment 1:
The parts by weight for preventing and treating the Chinese materia medica preparation raw material of sheep parasitic disease are as follows:
20 parts of Cortex Phellodendri, 20 parts of the coptis, 20 parts of radix scutellariae, 5 parts of ginger, 5 parts of the Chinese bulbul, 2 parts of granatum, 2 parts of garlic, brown sugar
0.5 part.
The Chinese materia medica preparation production method is: in parts by weight by dry Cortex Phellodendri, the coptis, radix scutellariae, ginger, hoary hair
Father-in-law, granatum and garlic are ground into 100-120 targeted fine powder；Medicinal powder is poured into extractor, water is added and impregnates 20-30 points
Clock is added 5-8 times that water is medicine gross weight, 90-100 DEG C of infusion 1-1.5 hours is then heated to, to fluid temperature
Brown sugar is added when being down to 30 DEG C -50 DEG C, stirring is filtered to get the Chinese materia medica preparation of prevention and treatment sheep parasitic disease.
Embodiment 2:
The parts by weight for preventing and treating the Chinese materia medica preparation raw material of sheep parasitic disease are as follows:
25 parts of Cortex Phellodendri, 25 parts of the coptis, 25 parts of radix scutellariae, 6 parts of ginger, 6 parts of the Chinese bulbul, 3 parts of granatum, 3 parts of garlic, brown sugar
0.6 part.
Its production method is same as Example 1.
Embodiment 3:
The parts by weight for preventing and treating the Chinese materia medica preparation raw material of sheep parasitic disease are as follows:
28 parts of Cortex Phellodendri, 28 parts of the coptis, 28 parts of radix scutellariae, 8 parts of ginger, 8 parts of the Chinese bulbul, 3 parts of granatum, 3 parts of garlic, brown sugar
0.8 part.
Its production method is same as Example 1.
Embodiment 4:
The parts by weight for preventing and treating the Chinese materia medica preparation raw material of sheep parasitic disease are as follows:
30 parts of Cortex Phellodendri, 30 parts of the coptis, 30 parts of radix scutellariae, 10 parts of ginger, 10 parts of the Chinese bulbul, 4 parts of granatum, 4 parts of garlic, brown sugar
1.0 part.
Its production method is same as Example 1.
Application Example
The Chinese materia medica preparation of prevention and treatment sheep parasitic disease of the invention is implemented in Nanning Heng County sheep cultivation base
It is on probation, it tests with fascioliasis, metenteron line parasitosis, sheep 30 of gastrointestinal nematode parasites, wherein suffering from liver slice
The sheep 10 of fluke disease, the sheep 10 with metenteron line parasitosis, sheep 10 with gastrointestinal nematode parasites.It will be of the invention
Chinese materia medica preparation be watered and taken to sheep；The Chinese materia medica preparation for taking 50ml of the invention every time, is blended into the drinking water of sheep, takes daily
With 2-3 times, a week is continuously taken, as a result illness sheep cure rate reaches 96% or more, in addition to 1 with fascioliasis
Sheep symptom it is more serious need other than chemotherapy, remaining 29 illness sheep is all cured；And it is usually each
The moon takes Chinese materia medica preparation of the invention 1-2 times, can prevent infringement of the helminth to sheep, has good control efficiency.
Claims (2)
1. a kind of Chinese materia medica preparation for preventing and treating sheep parasitic disease, it is characterised in that: the raw material including following parts by weight: Cortex Phellodendri
20-30 parts, it is 20-30 parts of the coptis, 20-30 parts of radix scutellariae, 5-10 parts of ginger, 5-10 parts of the Chinese bulbul, 2-4 parts of granatum, big
2-4 parts of garlic, 0.5-1.0 parts of brown sugar；
The Chinese materia medica preparation production method is: in parts by weight by dry Cortex Phellodendri, the coptis, radix scutellariae, ginger, the Chinese bulbul, stone
Pomegranate skin and garlic are ground into 100-120 targeted fine powder；Medicinal powder is poured into extractor, water is added and impregnates 20-30 points
Clock is added 5-8 times that water is medicine gross weight, 90-100 DEG C of infusion 1-1.5 hours is then heated to, to fluid temperature
Brown sugar is added when being down to 30 DEG C -50 DEG C, stirring is filtered to get the Chinese materia medica preparation of prevention and treatment sheep parasitic disease.
2. the Chinese materia medica preparation of the prevention and treatment sheep parasitic disease according to claim 1, it is characterised in that: including following heavy
Measure the raw material of number: 25 parts of Cortex Phellodendri, 25 parts of the coptis, 25 parts of radix scutellariae, 6 parts of ginger, 6 parts of the Chinese bulbul, granatum 3
Part, 3 parts of garlic, 0.6 part of brown sugar.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510529412.9A CN105126048B (en) | 2015-08-26 | 2015-08-26 | The Chinese materia medica preparation and its production method for preventing and treating sheep parasitic disease |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510529412.9A CN105126048B (en) | 2015-08-26 | 2015-08-26 | The Chinese materia medica preparation and its production method for preventing and treating sheep parasitic disease |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN105126048A CN105126048A (en) | 2015-12-09 |
| CN105126048B true CN105126048B (en) | 2019-01-11 |
Family
ID=54711859
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201510529412.9A Expired - Fee Related CN105126048B (en) | 2015-08-26 | 2015-08-26 | The Chinese materia medica preparation and its production method for preventing and treating sheep parasitic disease |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN105126048B (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105663234B (en) * | 2016-03-25 | 2019-11-01 | 阿勒泰地区畜牧工作站 | The Chinese medicine composition and its preparation method and application for treating sheep endoparasite |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20130143829A1 (en) * | 2011-12-06 | 2013-06-06 | Robert Holmes | Topical Combination Formulations of Macrocyclic Lactones with Synthetic Pyrethroids |
| CN103623071A (en) * | 2013-12-03 | 2014-03-12 | 湖北武当动物药业有限责任公司 | Powerful insect repellent for veterinary use and preparation method thereof |
-
2015
- 2015-08-26 CN CN201510529412.9A patent/CN105126048B/en not_active Expired - Fee Related
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20130143829A1 (en) * | 2011-12-06 | 2013-06-06 | Robert Holmes | Topical Combination Formulations of Macrocyclic Lactones with Synthetic Pyrethroids |
| CN103623071A (en) * | 2013-12-03 | 2014-03-12 | 湖北武当动物药业有限责任公司 | Powerful insect repellent for veterinary use and preparation method thereof |
Non-Patent Citations (1)
| Title |
|---|
| 用红糖大蒜治牛虫(疒积)增膘;葛树春等;《中兽医学杂志》;19831231(第01期);第64页，尤其是第1-2段 |
Also Published As
| Publication number | Publication date |
|---|---|
| CN105126048A (en) | 2015-12-09 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN105123612B (en) | Cultural method of the sheep in subtropical zone | |
| CN102078419B (en) | Medicament for preventing and treating porcine reproductive and respiratory syndrome (PRRS) and preparation method thereof | |
| CN104187172B (en) | Functional feed for treating enterogastritis diseases of turtles and preparation method of functional feed | |
| CN104799048A (en) | Feed capable of improving Truogx sinensis disease resistance, and preparation method thereof | |
| CN103893344A (en) | Chinese medicinal submicron powder for treating piglet's yellow-white dysentery and preparation method thereof | |
| CN102579701B (en) | Compound dandelion decoction | |
| CN104256166A (en) | Functional feed for treating bovine bluetongue and preparation method thereof | |
| CN102886014B (en) | Anticancer drug capable of clearing blood and diminishing inflammation | |
| CN104001045A (en) | Drug for treating dog pneumonia and preparation method thereof | |
| CN104472798A (en) | Herb tea capable of lowering hyperglycemia and preparation method thereof | |
| CN104799047A (en) | Chinese herbal medicine phagostimulant for Truogx sinensis and preparation method thereof | |
| CN103933292A (en) | Dysmenorrhea treating patch | |
| CN106389881A (en) | Ointment capable of invigorating blood circulation and dissipating blood stasis | |
| CN105126048B (en) | The Chinese materia medica preparation and its production method for preventing and treating sheep parasitic disease | |
| CN110433275A (en) | A kind of pharmaceutical composition for adjusting function of human body and preparation method thereof and purposes | |
| CN104189413A (en) | Medicine composition for treating enterogastritis diseases of turtles and preparation method of medicine composition | |
| CN108057115A (en) | A kind of composition for treating inflammation of upper respiratory tract infection and preparation method thereof | |
| CN104799007A (en) | Chinese herbal medicine additive for enhancing disease resistance of Truogx sinensis and preparation method thereof | |
| CN104472755A (en) | Herb tea capable of lowering hyperlipidemia and preparation method thereof | |
| CN103816399A (en) | Traditional Chinese medicinal preparation for treating canine distemper | |
| CN105168496B (en) | A kind of Chinese traditional medicine composition and preparation method preventing and treating Duck Hepatitis Virus | |
| CN108938835A (en) | " huge bucket dipping " improves outer bathing packet of precious jade medicine of nettle rash and preparation method thereof | |
| CN107296917A (en) | One kind preventing and treating wood frog red leg disease Chinese medicine composition | |
| CN102327440A (en) | Chinese herbal medicine for treating deep multiple abscess | |
| CN107693640A (en) | Precious jade medicine, which itches to be discontinued, bathes bag and preparation method thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20190111 |