CN108991527A - A kind of strengthen immunity ganoderma spove powder capsule - Google Patents
A kind of strengthen immunity ganoderma spove powder capsule Download PDFInfo
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- CN108991527A CN108991527A CN201810848873.6A CN201810848873A CN108991527A CN 108991527 A CN108991527 A CN 108991527A CN 201810848873 A CN201810848873 A CN 201810848873A CN 108991527 A CN108991527 A CN 108991527A
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- 241000222336 Ganoderma Species 0.000 title claims abstract description 60
- 239000002775 capsule Substances 0.000 title claims abstract description 38
- 230000036039 immunity Effects 0.000 title claims abstract description 28
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Classifications
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/105—Plant extracts, their artificial duplicates or their derivatives
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23P—SHAPING OR WORKING OF FOODSTUFFS, NOT FULLY COVERED BY A SINGLE OTHER SUBCLASS
- A23P10/00—Shaping or working of foodstuffs characterised by the products
- A23P10/30—Encapsulation of particles, e.g. foodstuff additives
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
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- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Botany (AREA)
- Mycology (AREA)
- Health & Medical Sciences (AREA)
- Nutrition Science (AREA)
- Medicines Containing Plant Substances (AREA)
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Abstract
The invention belongs to health product technology fields, especially a kind of strengthen immunity ganoderma spove powder capsule, is made of raw material from the following weight: 180 ~ 190 parts of ganoderma spove powder, modified starch starch 150 ~ 160 parts, 54 ~ 58 parts of hydroxypropyl methylcellulose solution, 21 ~ 23 parts of broken masson pine pollen, 25 ~ 27 parts of bamboo juice；Ganoderma total triterpenes content is not only made to reach 8.1% or more, effectively promote the activity of the effective active composition of lucidum spore powder, human body is improved to the conversion ratio that digests and absorbs of the effective active composition of lucidum spore powder, enhances human immunological competence, promotes health, and effectively facilitate the formation of Reishi sporule powder particles, particle surface is smooth, regular shape, and is not adhered between particle, and make it have stronger oxidation resistance, it is not easy oxidation deterioration, the shelf-life is 6 ~ 7 years.
Description
Technical field
The invention belongs to health product technology field, especially a kind of strengthen immunity ganoderma spove powder capsule.
Background technique
Lucidum spore powder is the seed that ganoderma lucidum generates release in development later stage, is the essence of ganoderma lucidum, non-under field conditions (factors)
Normal difficulty is collected, extremely rare precious；But lucidum spore powder has one layer of extremely difficult chitin digested by human body gastric acid to constitute
Outer wall, the lucidum spore powder human body of broken wall can not digested and assimilated, but at present existing wall breaking technology obtain broken wall spirit
Ganoderma lucidum spore powder, effective active composition release rate is low, reduces lucidum spore powder to the nutritional health function of human body, and Reishi sporule
The consaturated oil that powder contains is difficult to remove, and causes lucidum spore powder oxidizable and rotten.
In addition, people's lives are increasing with operating pressure as social competition is growing more intense；Meanwhile environmental pollution
Also increasingly severe, under the double action of intrinsic pressure and external environment, the constitution of people starts to be deteriorated people, often occurs
The defect such as flu, indigestion, insomnia, hypertension, hyperlipidemia, the situations such as immunity degradation, inferior health are increasingly common, so
Lucidum spore powder is made capsule and people is facilitated to take by people, thus to improve human health；But current existing technology system
At Ganoderma Lucidum Spore Powder Capsule be absorbed and utilized that conversion ratio is low, the strengthen immunity effect with its lucidum spore powder itself is no
It is prominent.
Turn it can be seen from the above, being badly in need of inventing a kind of ganoderma spove powder capsule to improve being absorbed and utilized for lucidum spore powder
Rate enhances its immune function to human body, promotes health.
Summary of the invention
In view of the above-mentioned problems, the present invention is intended to provide a kind of strengthen immunity ganoderma spove powder capsule.
The invention is realized by the following technical scheme:
A kind of strengthen immunity ganoderma spove powder capsule, is made of raw material from the following weight: ganoderma spove powder 180
~ 190 parts, modified starch starch 150 ~ 160 parts, 54 ~ 58 parts of hydroxypropyl methylcellulose solution, 21 ~ 23 parts of broken masson pine pollen, bamboo juice 25 ~
27 parts.
As invention further embodiment: the ganoderma spove powder is prepared according to the following steps: by ganoderma lucidum spore
It keeps the temperature and eluriates in the warm water that sub- powder merging temperature is 54 ~ 58 DEG C, separation, the vacuum freeze drying that merging temperature is -19 ~ -17 DEG C
It is dried in case to no moisture, is taken out, 5 ~ 7min of magnetization treatment, adjustment magnetic field are strong under conditions of merging magnetic field strength is 800 ~ 900G
Degree is that 1300 ~ 1400G continues 9 ~ 11min of magnetization treatment, and broken wall obtains ganoderma spove powder；Not only effectively break extremely difficult by people
The outer wall that the chitin of body gastric acid digestion is constituted, and the effective active composition of lucidum spore powder is not destroyed, promote lucidum spore powder
The release of effective active composition, and the consaturated oil that lucidum spore powder contains can be effectively removed, avoid aoxidizing and gone bad, it mentions
High effective active composition content improves human body to the absorption rate of lucidum spore powder effective active composition.
As invention further embodiment: the modified starch slurry is prepared: according to the following steps by 8 ~ 9 parts by weight
Tapioca and 12 ~ 13 parts by weight Red Bean Starch put into 380 ~ 400 parts by weight, temperature be 62 ~ 66 DEG C, mass fraction be
In 0.4% ~ 0.6% sodium-chloride water solution, the blender 32 ~ 38min of insulated and stirred for being 120 ~ 140r/min with revolving speed is passed through frequency
The ultrasonic echography that rate is 94 ~ 102kHz, power is 128 ~ 134W handles 13 ~ 17min, and adjustment frequency is 73 ~ 77kHz, power
Continue 13 ~ 17min of ultrasonic treatment for 93 ~ 97W, continues 15 ~ 20min of mild fire infusion after being boiled by slow fire and be 70 ~ 80r/ with revolving speed
The blender of min is constantly stirred, cooling, obtains modified starch slurry；Not only caking property is good, and atomization uniformly, effectively facilitates ganoderma lucidum
Conidia powder rapid condensation granulating, and lucidum spore powder disintegration can be effectively improved, shorten disintegration time, improves Reishi sporule
The quick-acting of powder.
As invention further embodiment: the hydroxypropyl methylcellulose solution is prepared: according to the following steps by 0.12
The hydroxypropyl methylcellulose of ~ 0.14 parts by weight puts into 3 ~ 4 parts by weight, temperature is in 74 ~ 80 DEG C of water, with revolving speed be 240 ~
Blender 44 ~ 48min of insulated and stirred of 280r/min, continue after being boiled by slow fire 25 ~ 30min of mild fire infusion and with revolving speed for 240 ~
The blender of 280r/min is constantly stirred, cooling, obtains hydroxypropyl methylcellulose solution.
As invention further embodiment: a kind of preparation method of strengthen immunity ganoderma spove powder capsule, specifically
The following steps are included:
(1) ganoderma spove powder, broken masson pine pollen and bamboo juice are put into fluidized bed granulation seed-coating machine, being heated to temperature is
50 DEG C, start to spray into modified starch slurry, control liquid supply speed is 0.8 ~ 1.0Hz, temperature is 50 ~ 60 DEG C and pelletizes, modified to form sediment
After slurry has been sprayed, ganoderma spove powder particle is obtained；
(2) ganoderma spove powder particle is heated to 60 DEG C, starts to spray into hydroxypropyl methylcellulose solution, control liquid supply speed is
0.8 ~ 1.0Hz, temperature are 60 ~ 70 DEG C and are coated that hydroxypropyl methylcellulose solution is dry controlled at 50 ~ 60 DEG C of heat preservations after having sprayed
Dry 10 ~ 15min obtains ganoderma spove powder coated granule；
(3) ganoderma spove powder coated granule merging pelletizing machine is crossed into 60 ~ 70 meshes and carries out whole grain, be placed in full-automatic filling glue
It in capsule machine, is filled in Capsules, every fills 240 ~ 260mg, is processed by shot blasting, filling, labelling obtains finished product.
Beneficial effects of the present invention: a kind of strengthen immunity ganoderma spove powder capsule provided by the invention, ganoderma lucidum are total
Triterpene content reaches 8.1% or more, and broken masson pine pollen and the effect of bamboo juice coordinated is added, effectively promotes having for lucidum spore powder
The activity of active constituent is imitated, improves human body to the conversion ratio that digests and absorbs of the effective active composition of lucidum spore powder, and
Human gastrointestinal tract can be promoted healthy, promote the proliferation of beneficial bacterium, effectively facilitate digestion and absorption of the human body to other nutriments
Ability improves nutrient utilization, to effectively enhance human body constitution, enhances human immunological competence, enhances human body to germ and disease
The resistivity of poison, effectively facilitates human health；Modified starch slurry of the invention and hydroxypropyl are used in granulation and coating process
Methylcellulose solution, effectively facilitates the formation of Reishi sporule powder particles, and particle surface is smooth, regular shape, and between particle not
It is adhered, and makes it have stronger oxidation resistance, be not easy oxidation deterioration, the shelf-life is 6 ~ 7 years, effectively improves ganoderma lucidum
The nutrition and health care utilization rate of conidia powder.
Specific embodiment
Illustrate the present invention with specific embodiment below, but is not limitation of the present invention.
Embodiment 1
In the embodiment of the present invention, a kind of strengthen immunity ganoderma spove powder capsule is made of raw material from the following weight: broken
180 parts of wall lucidum spore powder, modified starch starch 150 parts, 54 parts of hydroxypropyl methylcellulose solution, 21 parts of broken masson pine pollen, bamboo juice 25
Part.
As invention further embodiment: the ganoderma spove powder is prepared according to the following steps: by ganoderma lucidum spore
It keeps the temperature and eluriates in the warm water that sub- powder merging temperature is 54 DEG C, separate, it is dry in the vacuum freezing drying oven that merging temperature is -19 DEG C
It to no moisture, takes out, magnetization treatment 5min, adjustment magnetic field strength are that 1300G continues under conditions of merging magnetic field strength is 800G
Magnetization treatment 9min, broken wall obtain ganoderma spove powder；Not only effectively break the extremely difficult chitin digested by human body gastric acid to constitute
Outer wall, and do not destroy the effective active composition of lucidum spore powder, promote the release of lucidum spore powder effective active composition, and
The consaturated oil that lucidum spore powder contains can be effectively removed, avoid aoxidizing and is gone bad, effective active composition content is improved, is improved
Absorption rate of the human body to lucidum spore powder effective active composition.
As invention further embodiment: the modified starch slurry is prepared: according to the following steps by 8 parts by weight
The sodium chloride that the Red Bean Starch of tapioca and 12 parts by weight puts into 380 parts by weight, temperature is 62 DEG C, mass fraction is 0.4%
In aqueous solution, the blender insulated and stirred 32min for being 120r/min with revolving speed is passed through that frequency is 94kHz, power is the super of 128W
Sound wave is ultrasonically treated 13min, and adjustment frequency is 73kHz, power is that 93W continues to be ultrasonically treated 13min, continues text after being boiled by slow fire
The fiery infusion 15min and blender for being 70r/min with revolving speed is constantly stirred, it is cooling, obtain modified starch slurry；Not only caking property
Good, atomization uniformly, effectively facilitates lucidum spore powder rapid condensation granulating, and can effectively improve lucidum spore powder disintegration,
Shorten disintegration time, improves the quick-acting of lucidum spore powder.
As invention further embodiment: the hydroxypropyl methylcellulose solution is prepared: according to the following steps by 0.12
In the water that the hydroxypropyl methylcellulose of parts by weight puts into 3 parts by weight, temperature is 74 DEG C, protected with the blender that revolving speed is 240r/min
Temperature stirring 44min, after being boiled by slow fire continue mild fire infusion 25min and be 240r/min with revolving speed blender constantly stirred
It mixes, it is cooling, obtain hydroxypropyl methylcellulose solution.
As invention further embodiment: a kind of preparation method of strengthen immunity ganoderma spove powder capsule, specifically
The following steps are included:
(1) ganoderma spove powder, broken masson pine pollen and bamboo juice are put into fluidized bed granulation seed-coating machine, being heated to temperature is
50 DEG C, start to spray into modified starch slurry, control liquid supply speed is 0.8Hz, temperature is 50 DEG C and pelletizes, and modified starch slurry has sprayed
Afterwards, ganoderma spove powder particle is obtained；
(2) ganoderma spove powder particle is heated to 60 DEG C, starts to spray into hydroxypropyl methylcellulose solution, control liquid supply speed is
0.8Hz, temperature be 60 DEG C be coated, hydroxypropyl methylcellulose solution sprayed after controlled at 50 DEG C of heat preservation and dryness 10min, obtain
Ganoderma spove powder coated granule；
(3) ganoderma spove powder coated granule merging pelletizing machine is crossed into 60 meshes and carries out whole grain, be placed in full-automatic filling capsule
It in machine, is filled in Capsules, every dress 240mg is processed by shot blasting, filling, labelling obtains finished product.
Embodiment 2
In the embodiment of the present invention, a kind of strengthen immunity ganoderma spove powder capsule is made of raw material from the following weight: broken
185 parts of wall lucidum spore powder, modified starch starch 155 parts, 56 parts of hydroxypropyl methylcellulose solution, 22 parts of broken masson pine pollen, bamboo juice 26
Part.
As invention further embodiment: the ganoderma spove powder is prepared according to the following steps: by ganoderma lucidum spore
It keeps the temperature and eluriates in the warm water that sub- powder merging temperature is 56 DEG C, separate, it is dry in the vacuum freezing drying oven that merging temperature is -18 DEG C
It to no moisture, takes out, magnetization treatment 6min, adjustment magnetic field strength are that 1350G continues under conditions of merging magnetic field strength is 850G
Magnetization treatment 10min, broken wall obtain ganoderma spove powder；Not only effectively break the extremely difficult chitin texture digested by human body gastric acid
At outer wall, and do not destroy the effective active composition of lucidum spore powder, promote the release of lucidum spore powder effective active composition, and
And the consaturated oil that lucidum spore powder contains can be effectively removed, avoid aoxidizing and gone bad, effective active composition content is improved, is mentioned
Absorption rate of the high human body to lucidum spore powder effective active composition.
As invention further embodiment: the modified starch slurry is prepared: according to the following steps by 8.5 parts by weight
Tapioca and 12.5 parts by weight Red Bean Starch put into 390 parts by weight, the chlorine that temperature is 64 DEG C, mass fraction is 0.5%
Change sodium water solution in, the blender insulated and stirred 35min for being 130r/min with revolving speed, be passed through frequency be 98kHz, power 131W
Ultrasonic echography handle 15min, adjustment frequency be 75kHz, power be 95W continue be ultrasonically treated 15min, be boiled by slow fire subsequent
The continuous mild fire infusion 18min and blender for being 75r/min with revolving speed is constantly stirred, it is cooling, obtain modified starch slurry；Not only glue
Knot property is good, and atomization uniformly, effectively facilitates lucidum spore powder rapid condensation granulating, and can effectively improve lucidum spore powder disintegration
Property, shorten disintegration time, improves the quick-acting of lucidum spore powder.
As invention further embodiment: the hydroxypropyl methylcellulose solution is prepared: according to the following steps by 0.13
In the water that the hydroxypropyl methylcellulose of parts by weight puts into 3.5 parts by weight, temperature is 77 DEG C, the blender for being 260r/min with revolving speed
Insulated and stirred 46min, after being boiled by slow fire continue mild fire infusion 28min and be 260r/min with revolving speed blender constantly stirred
It mixes, it is cooling, obtain hydroxypropyl methylcellulose solution.
As invention further embodiment: a kind of preparation method of strengthen immunity ganoderma spove powder capsule, specifically
The following steps are included:
(1) ganoderma spove powder, broken masson pine pollen and bamboo juice are put into fluidized bed granulation seed-coating machine, being heated to temperature is
50 DEG C, start to spray into modified starch slurry, control liquid supply speed is 0.9Hz, temperature is 55 DEG C and pelletizes, and modified starch slurry has sprayed
Afterwards, ganoderma spove powder particle is obtained；
(2) ganoderma spove powder particle is heated to 60 DEG C, starts to spray into hydroxypropyl methylcellulose solution, control liquid supply speed is
0.9Hz, temperature be 65 DEG C be coated, hydroxypropyl methylcellulose solution sprayed after controlled at 55 DEG C of heat preservation and dryness 13min, obtain
Ganoderma spove powder coated granule；
(3) ganoderma spove powder coated granule merging pelletizing machine is crossed into 65 meshes and carries out whole grain, be placed in full-automatic filling capsule
It in machine, is filled in Capsules, every dress 250mg is processed by shot blasting, filling, labelling obtains finished product.
Embodiment 3
In the embodiment of the present invention, a kind of strengthen immunity ganoderma spove powder capsule is made of raw material from the following weight: broken
190 parts of wall lucidum spore powder, modified starch starch 160 parts, 58 parts of hydroxypropyl methylcellulose solution, 23 parts of broken masson pine pollen, bamboo juice 27
Part.
As invention further embodiment: the ganoderma spove powder is prepared according to the following steps: by ganoderma lucidum spore
It keeps the temperature and eluriates in the warm water that sub- powder merging temperature is 58 DEG C, separate, it is dry in the vacuum freezing drying oven that merging temperature is -17 DEG C
It to no moisture, takes out, magnetization treatment 7min, adjustment magnetic field strength are that 1400G continues under conditions of merging magnetic field strength is 900G
Magnetization treatment 11min, broken wall obtain ganoderma spove powder；Not only effectively break the extremely difficult chitin texture digested by human body gastric acid
At outer wall, and do not destroy the effective active composition of lucidum spore powder, promote the release of lucidum spore powder effective active composition, and
And the consaturated oil that lucidum spore powder contains can be effectively removed, avoid aoxidizing and gone bad, effective active composition content is improved, is mentioned
Absorption rate of the high human body to lucidum spore powder effective active composition.
As invention further embodiment: the modified starch slurry is prepared: according to the following steps by 9 parts by weight
The Red Bean Starch of tapioca and 13 parts by weight puts into 400 parts by weight, temperature is 66 DEG C, mass fraction is 0.4% ~ 0.6%
In sodium-chloride water solution, the blender insulated and stirred 38min for being 140r/min with revolving speed is passed through that frequency is 102kHz, power is
The ultrasonic echography of 134W handles 17min, and adjustment frequency is 77kHz, power is that 97W continues to be ultrasonically treated 17min, is boiled by slow fire
Continue mild fire infusion 20min afterwards and be 80r/min with revolving speed blender be constantly stirred, it is cooling, obtain modified starch slurry；No
But caking property is good, and atomization uniformly, effectively facilitates lucidum spore powder rapid condensation granulating, and can effectively improve lucidum spore powder
Disintegration shortens disintegration time, improves the quick-acting of lucidum spore powder.
As invention further embodiment: the hydroxypropyl methylcellulose solution is prepared: according to the following steps by 0.14
In the water that the hydroxypropyl methylcellulose of parts by weight puts into 4 parts by weight, temperature is 80 DEG C, protected with the blender that revolving speed is 280r/min
Temperature stirring 48min, after being boiled by slow fire continue mild fire infusion 30min and be 280r/min with revolving speed blender constantly stirred
It mixes, it is cooling, obtain hydroxypropyl methylcellulose solution.
As invention further embodiment: a kind of preparation method of strengthen immunity ganoderma spove powder capsule, specifically
The following steps are included:
(1) ganoderma spove powder, broken masson pine pollen and bamboo juice are put into fluidized bed granulation seed-coating machine, being heated to temperature is
50 DEG C, start to spray into modified starch slurry, control liquid supply speed is 1.0Hz, temperature is 60 DEG C and pelletizes, and modified starch slurry has sprayed
Afterwards, ganoderma spove powder particle is obtained；
(2) ganoderma spove powder particle is heated to 60 DEG C, starts to spray into hydroxypropyl methylcellulose solution, control liquid supply speed is
1.0Hz, temperature be 70 DEG C be coated, hydroxypropyl methylcellulose solution sprayed after controlled at 60 DEG C of heat preservation and dryness 15min, obtain
Ganoderma spove powder coated granule；
(3) ganoderma spove powder coated granule merging pelletizing machine is crossed into 70 meshes and carries out whole grain, be placed in full-automatic filling capsule
It in machine, is filled in Capsules, every dress 260mg is processed by shot blasting, filling, labelling obtains finished product.
Comparative example 1
Sesame people's hall board ganoderma spove powder capsule
Comparative example 2
A kind of strengthen immunity ganoderma spove powder capsule, the difference from embodiment 1 is that, it is added without broken masson pine pollen and bamboo
Drip, other conditions are all the same.
Experiment 1
Acute toxicity test
Experimental material: Kunming mouse, 20 ± 2g of weight, half male and half female；Strengthen immunity wall-breaking lucidum spore of the embodiment of the present invention
Sub- powder capsule, used time pour out content, are made into distilled water required for reagent liquid；
Experiment condition: 22 ~ 25 DEG C of temperature, humidity is 50% ~ 60%；
Experimental method: animal packet: each embodiment sets two dosage groups, every group of 10 mouse, half male and half female；It dosage and gives
Mode: experiment sets 4640,10000mg/kg, two dosage groups, is administered using oral stomach-filling mode, daily stomach-filling 1 time, continuous to see
It examines 7 days；Experimental result such as table 1:
1 Mouse Acute Toxicity experimental result of table
As shown in Table 1, have no that poisoning symptom and death condition, strengthen immunity broken wall of the present invention occurs in experiment mice in the observation period
Ganoderma Lucidum Spore Powder Capsule is greater than 10000mg/kg to the LD50 value of mouse, according to acute toxicity grading criteria, acute toxicity category
In practical non-toxic type.
Experiment 2
Strengthen immunity-animal experiment
Experiment purpose: examine whether product has the healthcare function of this strengthen immunity.
Experimental material: Kunming mouse, 20 ± 2g of weight, half male and half female；Sample: strengthen immunity of embodiment of the present invention broken wall spirit
Ganoderma lucidum spore powder capsule, used time pour out content；
Experiment condition: 22 ~ 25 DEG C of temperature, humidity is 50% ~ 60%；
Dosage selection gives mode with tested material: this experimental design 0.25g/kgBW, that is, the 5 of the quasi- dosage of people
Times, it takes sample 2.5g to add distilled water to 200mL, mixes well, by 0.2mL/10gBW stomach-filling, control group gives equivalent distillation
Water is at least continuously given 30 days once a day, and last to measuring indices after tested material for 24 hours；Experimental animal is divided into 3
Test big group, every group 60, then every group of 60 animals are divided into 6 experiment groups again, and every group 10, wherein 1 group of carry out mouse
Half hemolytic value (HC50) influences experiment, mouse antibodies cellulation influences experiment, mouse carbonic clearance influences experiment；Experimental result
Such as table 2:
2 mouse strengthen immunity experimental result of table
As shown in Table 2, for the pharmaceutical composition of orally administration various dose after 30 days, groups of animals vegetative activity is normal, mouse half
Number hemolysis value (HC50) influences experiment display, and the mouse half hemolytic value (HC50) of embodiment is higher than control group and comparative example, and
Difference is statistically significant；Mouse antibodies cellulation influences experiment display, and the mouse antibodies cellulation number of embodiment is higher than
Control group and comparative example, and difference is statistically significant；Mouse carbonic clearance influences experiment display, the mouse phagocytic index of embodiment
Higher than control group and comparative example, and difference is statistically significant；According to " health food examine with assessment technique specification " (2003
Version), strengthen immunity ganoderma spove powder capsule of the invention has stronger enhancing animal immunizing power function.
Claims (5)
1. a kind of strengthen immunity ganoderma spove powder capsule, which is characterized in that be made of raw material from the following weight: broken wall
180 ~ 190 parts of lucidum spore powder, 150 ~ 160 parts of modified starch slurry, 54 ~ 58 parts of hydroxypropyl methylcellulose solution, broken masson pine pollen 21 ~
23 parts, 25 ~ 27 parts of bamboo juice.
2. strengthen immunity ganoderma spove powder capsule according to claim 1, which is characterized in that the broken wall spirit
Ganoderma lucidum spore powder, is prepared according to the following steps:
It keeps the temperature and eluriates in the warm water for being 54 ~ 58 DEG C by lucidum spore powder merging temperature, separation, merging temperature is -19 ~ -17 DEG C
It is dried in vacuum freezing drying oven to no moisture, is taken out, magnetization treatment 5 under conditions of merging magnetic field strength is 800 ~ 900G ~
7min, adjustment magnetic field strength are that 1300 ~ 1400G continues 9 ~ 11min of magnetization treatment, and broken wall obtains ganoderma spove powder.
3. strengthen immunity ganoderma spove powder capsule according to claim 1, which is characterized in that the modified shallow lake
Slurry is prepared according to the following steps:
By the Red Bean Starch of the tapioca of 8 ~ 9 parts by weight and 12 ~ 13 parts by weight put into 380 ~ 400 parts by weight, temperature be 62 ~
66 DEG C, mass fraction be 0.4% ~ 0.6% sodium-chloride water solution in, with revolving speed be 120 ~ 140r/min blender insulated and stirred
32 ~ 38min is passed through the ultrasonic echography that frequency is 94 ~ 102kHz, power is 128 ~ 134W and handles 13 ~ 17min, adjusts frequency
It is that 93 ~ 97W continues 13 ~ 17min of ultrasonic treatment for 73 ~ 77kHz, power, continues 15 ~ 20min of mild fire infusion simultaneously after being boiled by slow fire
It is constantly stirred with the blender that revolving speed is 70 ~ 80r/min, it is cooling, obtain modified starch slurry.
4. strengthen immunity ganoderma spove powder capsule according to claim 1, which is characterized in that the hydroxypropyl first
Cellulose solution is prepared according to the following steps:
The hydroxypropyl methylcellulose of 0.12 ~ 0.14 parts by weight is put into 3 ~ 4 parts by weight, temperature to use revolving speed in 74 ~ 80 DEG C of water
For blender 44 ~ 48min of insulated and stirred of 240 ~ 280r/min, continues 25 ~ 30min of mild fire infusion after being boiled by slow fire and use revolving speed
It is constantly stirred for the blender of 240 ~ 280r/min, it is cooling, obtain hydroxypropyl methylcellulose solution.
5. the preparation method of described in any item strengthen immunity ganoderma spove powder capsules according to claim 1 ~ 4, special
Sign is, specifically includes the following steps:
(1) ganoderma spove powder, broken masson pine pollen and bamboo juice are put into fluidized bed granulation seed-coating machine, being heated to temperature is
50 DEG C, start to spray into modified starch slurry, control liquid supply speed is 0.8 ~ 1.0Hz, temperature is 50 ~ 60 DEG C and pelletizes, modified to form sediment
After slurry has been sprayed, ganoderma spove powder particle is obtained；
(2) ganoderma spove powder particle is heated to 60 DEG C, starts to spray into hydroxypropyl methylcellulose solution, control liquid supply speed is
0.8 ~ 1.0Hz, temperature are 60 ~ 70 DEG C and are coated that hydroxypropyl methylcellulose solution is dry controlled at 50 ~ 60 DEG C of heat preservations after having sprayed
Dry 10 ~ 15min obtains ganoderma spove powder coated granule；
(3) ganoderma spove powder coated granule merging pelletizing machine is crossed into 60 ~ 70 meshes and carries out whole grain, be placed in full-automatic filling glue
It in capsule machine, is filled in Capsules, every fills 240 ~ 260mg, is processed by shot blasting, filling, labelling obtains finished product.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810848873.6A CN108991527A (en) | 2018-07-28 | 2018-07-28 | A kind of strengthen immunity ganoderma spove powder capsule |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810848873.6A CN108991527A (en) | 2018-07-28 | 2018-07-28 | A kind of strengthen immunity ganoderma spove powder capsule |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112138031A (en) * | 2020-09-08 | 2020-12-29 | 广东都市菜族农业科技有限公司 | Preparation method and application of ganoderma lucidum spore powder extract containing ganoderma lucidum triterpene and ganoderma lucidum polysaccharide |
| CN113995123A (en) * | 2021-11-01 | 2022-02-01 | 刘隽彦 | Formula and preparation process of compound ganoderma lucidum spore powder with immunity effect |
-
2018
- 2018-07-28 CN CN201810848873.6A patent/CN108991527A/en not_active Withdrawn
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112138031A (en) * | 2020-09-08 | 2020-12-29 | 广东都市菜族农业科技有限公司 | Preparation method and application of ganoderma lucidum spore powder extract containing ganoderma lucidum triterpene and ganoderma lucidum polysaccharide |
| CN113995123A (en) * | 2021-11-01 | 2022-02-01 | 刘隽彦 | Formula and preparation process of compound ganoderma lucidum spore powder with immunity effect |
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Application publication date: 20181214 |