CN108991209A - 一种壳寡糖磷虾油夹心型凝胶糖果复合配方 - Google Patents
一种壳寡糖磷虾油夹心型凝胶糖果复合配方 Download PDFInfo
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Abstract
本发明公开了一种壳寡糖磷虾油夹心型凝胶糖果复合配方，由内容物和糖皮组成，所述内容物包含以下成分，磷虾油2‑5g，鱼油3.5‑3.8g，姜黄1.7‑2g，壳寡糖0.7‑1g。本发明具有促进受损细胞和骨折愈合，实现达到生骨护骨，促进关节恢复和骨折愈合，壳寡糖能够促进钙和矿物质的吸收，保护骨关节，从而达到缓解骨关节症状的目的。
Description
技术领域
本发明涉及分子生物学技术领域，尤其涉及一种壳寡糖磷虾油夹心型凝胶糖果复合配方。
背景技术
人的身体会随着年龄的不断增长而出现身体机能下降，还会由于增龄、肥胖、劳损、创伤、关节先天性异常和关节畸形等诸多因素引起的关节软骨退化损伤、关节边缘和软骨下骨反应性增生，多发为中老年人群，好发于负重关节及活动量较多的关节，例如颈椎、腰椎、膝关节和踝关节等，过度使用这些关节，均会加重退行性变化的发生。
姜黄素，这是一种世界公认的抗炎成分，对缓解炎症反应、风湿性关节炎，以及骨质疏松相关的疼痛和僵硬症状有显著效果，姜黄素还对多种肿瘤具有抑制作用，如肝癌、胃癌、大肠癌、食道癌、乳腺癌、前列腺癌、皮肤癌、淋巴瘤及白血病灯，还具备抗血管新生和抗纤维化作用，抗纤维化作用主要表现在抗肝纤维化、肺纤维化、肾纤维化和胰脏纤维化等。
发明内容
本发明提出了一种壳寡糖磷虾油夹心型凝胶糖果复合配方，具有促进骨细胞生成、修复受损细胞和抗炎排毒，消除导致关节病和关节疼痛的病源作用，具有广阔的开发前景，克服了现有技术中的缺陷。
本发明提供如下技术方案：一种壳寡糖磷虾油夹心型凝胶糖果复合配方，由内容物和糖皮组成，所述内容物包含以下成分，磷虾油2-5g，鱼油3.5-3.8g，姜黄1.7-2g，壳寡糖0.7-1g。
所述内容物包含以下成分：磷虾油2g，鱼油3.5g，姜黄1.7g，壳寡糖0.7g。
所述内容物包含以下成分：磷虾油3g，鱼油3.6g，姜黄1.8g，壳寡糖0.8g。
所述内容物包含以下成分：磷虾油4g，鱼油3.7g，姜黄1.9g，壳寡糖0.9g。
所述内容物包含以下成分：磷虾油5g，鱼油3.8g，姜黄2g，壳寡糖1g。
所述糖皮包含以下成分：明胶6g，淀粉7g，食用植物油10g，甘油8.4g，水11g。
一种壳寡糖磷虾油夹心型凝胶糖果复合配方加工方法，包括以下步骤：
S1:将配方量的磷虾油、姜黄和壳寡糖按比例称量后，通过高速胶体磨混合搅拌15-25分钟，得到混合均匀的混合物；
S2：再将鱼油按比例称量后，然后将S1中混合均匀的混合物与鱼油一起通过高速胶体磨混合均匀，得到混合均匀的混合物；
S3：然后将混合均匀的混合物加入乳化罐中乳化，控制环境在55-75℃搅拌3-7小时，放置1.5-3.5小时，经过150目筛网筛滤待用。
S4：将水加入化胶罐，接着加入明胶、淀粉、食用植物油和甘油，同时进行搅拌和加热，待混合完全后，放入保温桶内备用。
S5：将内容物和糖皮一起通过自动压丸机压制，控制生产环境温度13-23℃，压直完成后进行定型、洗丸和干燥后，制成凝胶糖果。
优选的，根据S4中的操作步骤，当温度升至65℃时，再加入明胶，搅拌35分钟直至完全溶解，然后温度升至85℃时脱气至无气泡状态，放入保温桶内保温至60℃备用。
优选的，根据S1和S2中的操作步骤，搅拌速度为14000转，流量为700（l/h)，线速度为40(m/s)。
优选的，根据S5中的操作步骤，控制干燥室温度29-36℃，相对湿度20-33％，干燥时间为26小时。
本发明提供了一种壳寡糖磷虾油夹心型凝胶糖果复合配方。首先，从加速骨细胞形成、促进钙、矿物质吸收入手，以此促进受损细胞和骨折愈合，实现达到生骨护骨。其次，从抗内毒、清除内毒素入手，清除导致关节病痛的因素，通过甲壳素和壳寡糖配合，其中甲壳素中，其衍生物氨糖能促进合成软骨细胞蛋白多糖，加速骨细胞形成，并催生关节滑液，促进关节恢复和骨折愈合，壳寡糖能够促进钙和矿物质的吸收，保护骨关节，从而达到缓解骨关节病症的目的。
具体实施方式
下面，通过具体实施例对本发明的技术方案进行详细说明。
一种壳寡糖磷虾油夹心型凝胶糖果复合配方，由内容物和糖皮组成，所述内容物包含以下成分：磷虾油2-5g，鱼油3.5-3.8g，姜黄1.7-2g，壳寡糖0.7-1g。
所述糖皮包含以下成分：明胶6g，淀粉7g，食用植物油10g，甘油8.4g，水11g。
实施例一
所述内容物包含以下成分：磷虾油2g，鱼油3.5g，姜黄1.7g，壳寡糖0.7g。
实施例二
所述内容物包含以下成分，其特征在于：磷虾油3g，鱼油3.6g，姜黄1.8g，壳寡糖0.8g。
实施例三
所述内容物包含以下成分：磷虾油4g，鱼油3.7g，姜黄1.9g，壳寡糖0.9g。
实施例四
所述内容物包含以下成分：磷虾油5g，鱼油3.8g，姜黄2g，壳寡糖1g。
一种壳寡糖磷虾油夹心型凝胶糖果复合配方加工方法，包括以下步骤：
S1:将配方量的磷虾油、姜黄和壳寡糖按比例称量后，通过高速胶体磨混合搅拌15-25分钟，得到混合均匀的混合物，S2：再将鱼油按比例称量后，然后将S1中混合均匀的混合物与鱼油一起通过高速胶体磨混合均匀，得到混合均匀的混合物，搅拌速度为14000转，流量为700（l/h)，线速度为40(m/s)，S3：然后将混合均匀的混合物加入乳化罐中乳化，控制环境在55-75℃搅拌3-7小时，放置1.5-3.5小时，经过150目筛网筛滤待用，S4：将水加入化胶罐，接着加入明胶、淀粉、食用植物油和甘油，同时进行搅拌和加热，待混合完全后，放入保温桶内备用，当温度升至65℃时，再加入明胶，搅拌35分钟直至完全溶解，然后温度升至85℃时脱气至无气泡状态，放入保温桶内保温至60℃备用，S5：将内容物和糖皮一起通过自动压丸机压制，控制生产环境温度13-23℃，压直完成后进行定型、洗丸和干燥后，制成凝胶糖果，控制干燥室温度29-36℃，相对湿度20-33％，干燥时间为26小时。
综上所述，本发明提供了一种壳寡糖磷虾油夹心型凝胶糖果复合配方，首先，从加速骨细胞形成、促进钙、矿物质吸收入手，以此促进受损细胞和骨折愈合，实现达到生骨护骨，其次，从抗内毒、清除内毒素入手，清除导致关节病痛的因素，通过甲壳素和壳寡糖配合，其中甲壳素中，其衍生物氨糖能促进合成软骨细胞蛋白多糖，加速骨细胞形成，并催生关节滑液，促进关节恢复和骨折愈合，壳寡糖能够促进钙和矿物质的吸收，保护骨关节，从而达到缓解骨关节病症的目的。
以上所述，仅为本发明较佳的具体实施方式，但本发明的保护范围并不局限于此，任何熟悉本技术领域的技术人员在本发明揭露的技术范围内，根据本发明的技术方案及其发明构思加以等同替换或改变，都应涵盖在本发明的保护范围。
Claims (10)
1.一种壳寡糖磷虾油夹心型凝胶糖果复合配方，由内容物和糖皮组成，所述内容物包含以下成分，其特征在于：磷虾油2-5g，鱼油3.5-3.8g，姜黄1.7-2g，壳寡糖0.7-1g。
2.根据权利要求1所述的一种壳寡糖磷虾油夹心型凝胶糖果复合配方，所述内容物包含以下成分，其特征在于：磷虾油2g，鱼油3.5g，姜黄1.7g，壳寡糖0.7g。
3.根据权利要求1所述的 后一种壳寡糖磷虾油夹心型凝胶糖果复合配方，所述内容物包含以下成分，其特征在于：磷虾油3g，鱼油3.6g，姜黄1.8g，壳寡糖0.8g。
4.根据权利要求1所述的一种壳寡糖磷虾油夹心型凝胶糖果复合配方，所述内容物包含以下成分，其特征在于：磷虾油4g，鱼油3.7g，姜黄1.9g，壳寡糖0.9g。
5.根据权利要求1所述的一种壳寡糖磷虾油夹心型凝胶糖果复合配方，所述内容物包含以下成分，其特征在于：磷虾油5g，鱼油3.8g，姜黄2g，壳寡糖1g。
6.根据权利要求1所述的一种壳寡糖磷虾油夹心型凝胶糖果复合配方，所述糖皮包含以下成分，其特征在于：明胶6g，淀粉7g，食用植物油10g，甘油8.4g，水11g。
7.一种壳寡糖磷虾油夹心型凝胶糖果复合配方加工方法，其特征在于，包括以下步骤：
S1:将配方量的磷虾油、姜黄和壳寡糖按比例称量后，通过高速胶体磨混合搅拌15-25分钟，得到混合均匀的混合物；
S2：再将鱼油按比例称量后，然后将S1中混合均匀的混合物与鱼油一起通过高速胶体磨混合均匀，得到混合均匀的混合物；
S3：然后将混合均匀的混合物加入乳化罐中乳化，控制环境在55-75℃搅拌3-7小时，放置1.5-3.5小时，经过150目筛网筛滤待用；
S4：将水加入化胶罐，接着加入明胶、淀粉、食用植物油和甘油，同时进行搅拌和加热，待混合完全后，放入保温桶内备用；
S5：将内容物和糖皮一起通过自动压丸机压制，控制生产环境温度13-23℃，压直完成后进行定型、洗丸和干燥后，制成凝胶糖果。
8.根据权利要求7所述的一种壳寡糖磷虾油夹心型凝胶糖果复合配方，其特征在于：根据S4中的操作步骤，当温度升至65℃时，再加入明胶，搅拌35分钟直至完全溶解，然后温度升至85℃时脱气至无气泡状态，放入保温桶内保温至60℃备用。
9.根据权利要求7所述的一种壳寡糖磷虾油夹心型凝胶糖果复合配方，其特征在于：根据S1和S2中的操作步骤，搅拌速度为14000转，流量为700（l/h)，线速度为40(m/s)。
10.根据权利要求7所述的一种壳寡糖磷虾油夹心型凝胶糖果复合配方，其特征在于：根据S5中的操作步骤，控制干燥室温度29-36℃，相对湿度20-33％，干燥时间为26小时。
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| WO2021209493A3 (en) * | 2020-04-15 | 2022-01-20 | Solyplus Gmbh | Means and methods of preventing and treating infections |
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