CN108969664B - External analgesic liquid medicine and preparation method and preparation device thereof - Google Patents
External analgesic liquid medicine and preparation method and preparation device thereof Download PDFInfo
- Publication number
- CN108969664B CN108969664B CN201810999194.9A CN201810999194A CN108969664B CN 108969664 B CN108969664 B CN 108969664B CN 201810999194 A CN201810999194 A CN 201810999194A CN 108969664 B CN108969664 B CN 108969664B
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- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation or decoction
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
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Abstract
The invention discloses an external analgesic liquid medicine and a preparation method and a preparation device thereof, wherein the preparation method comprises the steps of material selection, primary crushing, soaking, primary boiling, filtering, secondary crushing, secondary boiling, remixing and disinfection, the preparation device comprises a mixed boiling mechanism and six crushing mechanisms which are uniformly distributed on the edge of the top of the mixed boiling mechanism along the circumferential direction, and a stirring mechanism is vertically arranged in the center of the top of the mixed boiling mechanism. The analgesic liquid medicine has the advantages of quick drug effect exertion, no toxic or side effect on liver, analgesic effect and treatment effect, no adverse stimulation to skin, obvious analgesic effect and definite analgesic effect, is more convenient to use than oral analgesic medicines and injection analgesic medicines, has simple preparation method flow, provides better guarantee for the quality of the analgesic liquid medicine, can be combined with a preparation method, meets the use requirements of all steps of the whole preparation method, greatly improves the preparation efficiency of the analgesic liquid medicine, and ensures the safety and the quality of the analgesic liquid medicine.
Description
Technical Field
The invention belongs to the field of analgesics, and particularly relates to an external analgesic liquid medicine, and a preparation method and a preparation device thereof.
Background
The existing analgesics are mostly oral preparations or injections, the oral analgesics generally can exert drug effect after being absorbed by gastrointestinal tract, the analgesic effect is slow, and the drugs have certain stimulation effect on the gastrointestinal tract on one hand, so that the gastrointestinal tract feels uncomfortable; on the other hand, digestive juice in the gastrointestinal tract has certain destructive effect on the medicine, and the curative effect of the medicine is reduced. Although the analgesic injection has a faster action than the oral analgesic, it should endure the bitter taste of skin and flesh. The oral analgesic or the injection analgesic has the functions of relieving pain by blood circulation or acting on central nerve or local nerve, and finally is detoxified and discharged out of the body by the liver, so the oral analgesic or the injection analgesic has certain toxic and side effects on the liver. Especially, some patients with advanced tumor have severe cancer pain, and need to inject dolantin to relieve pain, which can cause dependence on dolantin in a few days, and the pain can be relieved by increasing dosage. The above analgesics generally have only analgesic effect and no therapeutic effect.
Disclosure of Invention
The invention aims to overcome the problems in the prior art and provides an external analgesic liquid medicine, a preparation method and a preparation device thereof, which have the advantages of quick drug effect exertion, no toxic or side effect on liver and analgesic and therapeutic effects.
In order to achieve the technical purpose and achieve the technical effect, the invention is realized by the following technical scheme:
an external analgesic liquid medicine is composed of the following components in parts by weight:
1-5 parts of myrrh, 3-7 parts of dragon's blood, 2-6 parts of eucommia bark, 2-7 parts of dried rehmannia root, 1-5 parts of gardenia, 0.5-3.5 parts of ligusticum wallichii, 2-5 parts of magnolia officinalis, 0.5-1.5 parts of rhizoma arisaematis, 4-9 parts of angelica dahurica, 1-3 parts of salvia miltiorrhiza, 7-11 parts of rabdosia rubescens, 1-3 parts of radix clematidis, 0.5-2.5 parts of honeysuckle and 2-5 parts of storax, 2-7 parts of red paeony root, 1-3 parts of tall gastrodia tuber, 3-7 parts of manchurian wildginger herb, 2-6 parts of sanchi, 4-6 parts of Chinese alangium root, 3-8 parts of pinellia tuber, 5-7 parts of mint, 2-4 parts of calamus, 4-8 parts of doubleteeth pubescent angilica root, 1-5 parts of plantain herb, 1-5 parts of baical skullcap root, 2-4 parts of cassia seed, 4-7 parts of borneol and 1-5 parts of garden balsam stem.
Furthermore, the solvent of the analgesic liquid medicine is prepared by mixing menthocamphorate, dew and ethanol, and the volume ratio of the menthocamphorate to the dew to the ethanol is 1: 3:1.
Further, the analgesic liquid medicine consists of the following components in parts by weight: 3 parts of myrrh, 4 parts of dragon's blood, 5 parts of eucommia bark, 3 parts of radix rehmanniae recen, 2 parts of cape jasmine fruit, 2 parts of ligusticum wallichii, 4 parts of mangnolia officinalis, 1 part of rhizoma arisaematis, 6 parts of angelica dahurica, 2 parts of salvia miltiorrhiza, 8 parts of rabdosia rubescens, 2 parts of radix clematidis, 2 parts of honeysuckle, 3 parts of storax, 5 parts of red paeony root, 2 parts of gastrodia elata, 4 parts of asarum, 3 parts of pseudo-ginseng, 5 parts of alangium chinense, 6 parts of pinellia ternate, 6 parts of mint, 3 parts of acorus calamus, 5 parts of radix angelicae pubescentis, 2 parts of plantain herb, 2.
The invention also provides a preparation method of the external analgesic liquid medicine, which comprises the following steps:
the method comprises the following steps: selecting materials: weighing the components in proportion, cleaning with distilled water, removing impurities and dirt, and naturally drying to obtain a mixed raw material;
step two: first-stage crushing: crushing the mixed raw materials, and then grinding into primary raw material powder of 10-20 meshes;
step three: soaking: adding the primary raw material powder into distilled water, and soaking for 30-50 hours to form a soaking mixture;
step four: first-stage boiling: boiling the soaked mixture for 3-5 hr, and standing for 10-20 min to form medicinal liquid separation mixture;
step five: and (3) filtering: filtering and separating solid and liquid in the liquid medicine separation mixture;
step six: secondary crushing: crushing the solid after filtering the liquid medicine separation mixture, and then grinding to form secondary raw material powder of 300-400 meshes;
step six: secondary boiling: mixing the secondary raw material powder with distilled water of the same volume, stirring, and boiling for 1-2 hours to obtain a powder treatment medicine;
step seven: and (3) remixing: mixing and stirring the liquid obtained after filtering the mixture of the powder treatment medicine and the liquid medicine separation evenly to form a liquid medicine finished product;
step eight: and (3) disinfection: and sterilizing the finished liquid medicine, and packaging and storing.
Further, the solvent prepared by mixing the essential balm, the dew and the ethanol is added after the mixture is uniformly stirred in the seventh step, and the mixture is stirred again.
Further, the stirring speed in the seventh step is 800-.
The invention also provides a preparation device of the external analgesic liquid medicine, which comprises a mixing and boiling mechanism and six crushing mechanisms uniformly distributed on the edge of the top of the mixing and boiling mechanism along the circumferential direction, wherein the center of the top of the mixing and boiling mechanism is vertically provided with a stirring mechanism;
the mixed boiling mechanism comprises a support mounting seat and a boiling collecting seat fixedly mounted at the bottom of the support mounting seat, and an external heating ring and an internal heating ring are respectively mounted in the support mounting seat; the supporting and mounting seat comprises an annular top plate, an outer peripheral tube is vertically arranged on the outer side of the bottom of the annular top plate, an inner peripheral tube is vertically arranged on the inner side of the bottom of the annular top plate, a first annular clamping groove is formed in the middle of the inner wall of the outer peripheral tube, a second annular clamping groove is formed in the middle of the inner wall of the inner peripheral tube, an outer heating ring is mounted in the first annular clamping groove, an inner heating ring is mounted in the second annular clamping groove, a flow guide cavity is formed between the outer peripheral tube and the inner peripheral tube, six first flow guide tubes vertically communicated with the flow guide cavity are uniformly distributed on the surface of the annular top plate along the circumferential direction; the surface of the boiling and collecting seat is provided with an annular collecting groove;
the crushing mechanism comprises a guide mounting cylinder and a raw material collecting cover fixedly mounted at the bottom of the guide mounting cylinder, a crushing and collecting seat is fixedly mounted at the bottom of the raw material collecting cover, a crushing and separating mechanism is horizontally mounted between the raw material collecting cover and the crushing and collecting seat, a driving mounting top plate is horizontally mounted at the top of the guide mounting cylinder, a hydraulic cylinder is vertically mounted in the center of the driving mounting top plate, a crushing mechanism is mounted in the guide mounting cylinder, and the crushing mechanism comprises a crushing base, a transition spring and a crushing top seat which are sequentially mounted from bottom to top; a guide mounting hole is formed in the center of the driving mounting top plate, and a piston rod of the hydraulic cylinder penetrates through the guide mounting hole to be fixedly connected with the crushing top seat;
an external thread cylinder is arranged on the inner side of the bottom of the guide mounting cylinder, the top of the raw material collecting cover is a circular opening, the bottom of the raw material collecting cover is a square opening, an internal thread cylinder matched with the external thread cylinder is arranged on the outer side of the top of the raw material collecting cover, four positioning screw holes which are distributed in a rectangular shape are uniformly distributed on the periphery of the bottom of the raw material collecting cover, and a first limiting clamping groove is uniformly distributed between every two adjacent positioning screw holes along the linear direction;
the crushing base comprises a crushing bottom plate and a guide sliding column vertically arranged in the center of the crushing bottom plate, and anti-rotation bulges are uniformly distributed on the periphery of the guide sliding column; a transition spring is arranged on the outer side of the guide sliding column; the crushing top seat comprises a crushing top plate and a sliding compression column vertically arranged in the center of the bottom of the crushing top plate, a guide sliding hole matched with the guide sliding column is formed in the center of the bottom of the sliding compression column, anti-rotation clamping grooves matched with the anti-rotation bulges are uniformly distributed in the inner side of the guide sliding hole, the bottom of the transition spring is in contact connection with the crushing bottom plate, and the top of the transition spring is in contact connection with the sliding compression column;
the crushing and separating mechanism comprises a plurality of separating pieces which are uniformly distributed at the bottom of the raw material collecting cover, and the plurality of separating pieces form a criss-cross net-shaped structure;
the separating piece comprises a central thin rod, mounting positioning rods matched with the first limiting clamping grooves are symmetrically arranged at two ends of the central thin rod, and limiting balls are arranged at the outer ends of the mounting positioning rods;
the crushing and collecting seat comprises a square connecting block fixed at the bottom of the raw material collecting cover, a second flow guide pipe communicated with the first flow guide pipe is vertically arranged in the center of the bottom of the square connecting block, four positioning through holes corresponding to the positioning screw holes are uniformly distributed on the periphery of the top surface of the square connecting block, a second limiting clamping groove corresponding to the first limiting clamping groove is uniformly distributed between every two adjacent positioning through holes, a crushing and collecting groove with a wide upper part and a narrow lower part is arranged in the center of the top surface of the square connecting block, and the bottom of the crushing and collecting groove is communicated;
the stirring mechanism comprises a grinding enclosure and a feeding collecting cover fixedly arranged at the top of the grinding enclosure, the bottom of the grinding enclosure is vertically provided with a stirring piece, and the middle of the grinding enclosure is provided with a grinding mechanism;
the grinding mechanism comprises horizontal grinding mechanisms which are uniformly distributed along the vertical direction, each horizontal grinding mechanism comprises a rotary grinding assembly which is sequentially installed along the horizontal linear direction, each rotary grinding assembly consists of two grinding rotating shafts with opposite rotation directions, and two rotary installation shafts are symmetrically arranged at two ends of each grinding rotating shaft;
the top of the feeding collecting cover is a circular opening, the bottom of the feeding collecting cover is a square opening, the grinding surrounding cover is of a square barrel structure, and rotary mounting holes matched with the rotary mounting shafts are uniformly distributed in the front side and the rear side of the grinding surrounding cover;
the stirring part comprises a stirring cylinder and a stirring and collecting cover arranged at the top of the stirring cylinder, six obliquely arranged flow guide inclined pipes are uniformly distributed at the bottom of the stirring cylinder along the circumferential direction, the top of each flow guide inclined pipe is communicated with the stirring cylinder, and the bottom of each flow guide inclined pipe is communicated with an inclined support pipe; a stirring mounting column is arranged at the center of the inner bottom surface of the stirring cylinder, a stirring mounting hole is formed in the center of the stirring mounting column, and a stirrer is arranged in the stirring mounting hole; the top of the stirring and collecting cover is a square opening, and the bottom of the stirring and collecting cover is a round opening.
Further, the grinding surrounding cover is connected with the stirring collecting cover and the grinding surrounding cover is connected with the feeding collecting cover through welding.
Further, the raw material collecting cover is fixedly connected with the square connecting block through bolts.
Furthermore, check valves are arranged between the second flow guide pipe and the flow guide inclined pipe.
The invention has the beneficial effects that:
the analgesic liquid medicine has the advantages of quick drug effect exertion, no toxic or side effect on liver, analgesic effect and treatment effect, no adverse stimulation to skin, obvious analgesic effect and definite analgesic effect, is more convenient to use than oral analgesic and injection analgesic, has simple preparation method flow and convenient preparation, and provides better guarantee for the quality of the analgesic liquid medicine.
Drawings
The accompanying drawings, which are included to provide a further understanding of the invention and are incorporated in and constitute a part of this application, illustrate embodiment(s) of the invention and together with the description serve to explain the invention without limiting the invention. In the drawings:
FIG. 1 is a schematic view of the construction of a production apparatus in the present invention;
FIG. 2 is an exploded view of a partial structure of a manufacturing apparatus according to the present invention;
FIG. 3 is an exploded view of a partial structure of a manufacturing apparatus according to the present invention;
FIG. 4 is a schematic view of a partial structure of a production apparatus in the present invention;
FIG. 5 is an exploded view of a partial structure of a manufacturing apparatus according to the present invention;
FIG. 6 is an exploded view of a partial structure of a manufacturing apparatus in the present invention;
FIG. 7 is an exploded view of a partial structure of a manufacturing apparatus in the present invention;
FIG. 8 is a schematic view of a partial structure of a production apparatus in the present invention;
FIG. 9 is a schematic view of a partial structure of a production apparatus in the present invention;
FIG. 10 is a schematic view of a partial structure of a production apparatus in the present invention;
FIG. 11 is a schematic view of a partial structure of a production apparatus in the present invention;
FIG. 12 is a schematic view of a partial structure of a production apparatus in the present invention;
FIG. 13 is a schematic view of a partial structure of a production apparatus in the present invention;
FIG. 14 is a schematic view of a partial structure of a production apparatus in the present invention.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
In the description of the present invention, it is to be understood that the terms "opening," "upper," "lower," "thickness," "top," "middle," "length," "inner," "peripheral," and the like are used in an orientation or positional relationship that is merely for convenience in describing and simplifying the description, and do not indicate or imply that the referenced component or element must have a particular orientation, be constructed and operated in a particular orientation, and thus should not be considered as limiting the present invention.
Example 1:
an external analgesic liquid medicine is composed of the following components in parts by weight:
1 part of myrrh, 3 parts of dragon's blood, 2 parts of eucommia bark, 2 parts of radix rehmanniae recen, 1 part of cape jasmine fruit, 0.5 part of ligusticum wallichii, 2 parts of mangnolia officinalis, 0.5 part of rhizoma arisaematis, 4 parts of angelica dahurica, 1 part of salvia miltiorrhiza, 7 parts of rabdosia rubescens, 1 part of radix clematidis, 0.5 part of honeysuckle, 2 parts of storax, 2 parts of red paeony root, 1 part of rhizoma gastrodiae, 3 parts of asarum, 2 parts of pseudo-ginseng, 4 parts of Chinese alangium, 3 parts of pinellia ternate, 5 parts of mint, 2 parts of calamus, 4 parts of radix angelicae pubescentis, 1 part of plantain herb, 1 part of scutellaria baicalensis, 2 parts of semen cassiae, 4 parts of borneol and 1 part of garden balsam stem, wherein a solvent of the analgesic: 3:1.
Example 2:
an external analgesic liquid medicine is composed of the following components in parts by weight: 5 parts of myrrh, 7 parts of dragon's blood, 6 parts of eucommia bark, 7 parts of radix rehmanniae recen, 5 parts of cape jasmine fruit, 3.5 parts of ligusticum wallichii, 5 parts of mangnolia officinalis, 1.5 parts of rhizoma arisaematis, 9 parts of angelica dahurica, 3 parts of salvia miltiorrhiza, 11 parts of rabdosia rubescens, 3 parts of radix clematidis, 2.5 parts of honeysuckle, 5 parts of storax, 7 parts of red paeony root, 3 parts of gastrodia elata, 7 parts of asarum, 6 parts of pseudo-ginseng, 6 parts of Chinese alangium, 8 parts of pinellia ternate, 7 parts of mint, 4 parts of calamus, 8 parts of radix angelicae pubescentis, 5 parts of plantain herb, 5 parts of scutellaria baicalensis, 4 parts of semen cassiae, 7 parts of borneol and 5 parts of garden balsam stem, wherein a solvent of the analgesic liquid: 3:1.
Example 3:
an external analgesic liquid medicine is composed of the following components in parts by weight: 3 parts of myrrh, 4 parts of dragon's blood, 5 parts of eucommia bark, 3 parts of radix rehmanniae recen, 2 parts of cape jasmine fruit, 2 parts of ligusticum wallichii, 4 parts of mangnolia officinalis, 1 part of rhizoma arisaematis, 6 parts of angelica dahurica, 2 parts of salvia miltiorrhiza, 8 parts of rabdosia rubescens, 2 parts of radix clematidis, 2 parts of honeysuckle, 3 parts of storax, 5 parts of red paeony root, 2 parts of rhizoma gastrodiae, 4 parts of asarum, 3 parts of pseudo-ginseng, 5 parts of alangium chinense, 6 parts of pinellia ternate, 6 parts of mint, 3 parts of acorus calamus, 5 parts of radix angelicae pubescentis, 2 parts of plantain herb, 2 parts of scutellaria baicalensis, 3 parts of semen cassiae, 5 parts of borneol and 2 parts of garden balsam stem, wherein a solvent: 3:1.
Example 4:
the invention also provides a preparation method of the external analgesic liquid medicine, which comprises the following steps:
the method comprises the following steps: selecting materials: weighing the components in proportion, cleaning with distilled water, removing impurities and dirt, and naturally drying to obtain a mixed raw material;
step two: first-stage crushing: crushing the mixed raw materials, and then grinding into primary raw material powder of 10-20 meshes;
step three: soaking: adding the primary raw material powder into distilled water, and soaking for 30-50 hours to form a soaking mixture;
step four: first-stage boiling: boiling the soaked mixture for 3-5 hr, and standing for 10-20 min to form medicinal liquid separation mixture;
step five: and (3) filtering: filtering and separating solid and liquid in the liquid medicine separation mixture;
step six: secondary crushing: crushing the solid after filtering the liquid medicine separation mixture, and then grinding to form secondary raw material powder of 300-400 meshes;
step six: secondary boiling: mixing the secondary raw material powder with distilled water of the same volume, stirring, and boiling for 1-2 hours to obtain a powder treatment medicine;
step seven: and (3) remixing: mixing and stirring the liquid obtained after filtering the mixture of the powder treatment medicine and the liquid medicine separation evenly to form a liquid medicine finished product, adding a solvent prepared by mixing cooling oil, dew and ethanol after stirring evenly, and stirring again at the stirring speed of 800-;
step eight: and (3) disinfection: and sterilizing the finished liquid medicine, and packaging and storing.
Example 5:
as shown in figure 1, the invention also provides a preparation device of the external analgesic liquid medicine, which comprises a mixing and boiling mechanism 1 and six crushing mechanisms 2 uniformly distributed at the top edge of the mixing and boiling mechanism 1 along the circumferential direction, wherein a stirring mechanism 3 is vertically arranged at the center of the top of the mixing and boiling mechanism 1.
As shown in fig. 2 and 3, the mixed boiling mechanism 1 comprises a supporting installation seat 11 and a boiling collecting seat 14 fixedly installed at the bottom of the supporting installation seat 11, wherein an outer heating ring 12 and an inner heating ring 13 are respectively installed inside the supporting installation seat 11; the supporting and mounting seat 11 comprises an annular top plate 111, an outer surrounding cylinder 112 is vertically arranged on the outer side of the bottom of the annular top plate 111, an inner surrounding cylinder 113 is vertically arranged on the inner side of the bottom of the annular top plate 111, a first annular clamping groove 114 is arranged in the middle of the inner wall of the outer surrounding cylinder 112, a second annular clamping groove 115 is arranged in the middle of the inner wall of the inner surrounding cylinder 113, an outer heating ring 12 is arranged in the first annular clamping groove 114, an inner heating ring 13 is arranged in the second annular clamping groove 115, a flow guide cavity is formed between the outer surrounding cylinder 112 and the inner surrounding cylinder 113, six first flow guide pipes 116 vertically communicated with the flow guide cavity are uniformly distributed on the surface of the annular top plate 111 along the circumferential direction; the surface of the boiling collection base 14 is provided with an annular collection groove 141.
As shown in fig. 4 and 5, the crushing mechanism 2 includes a guide mounting cylinder 21 and a raw material collecting cover 22 fixedly mounted at the bottom of the guide mounting cylinder 21, a crushing collecting seat 23 is fixedly mounted at the bottom of the raw material collecting cover 22, a crushing separating mechanism 24 is horizontally mounted between the raw material collecting cover 22 and the crushing collecting seat 23, a driving mounting top plate 25 is horizontally mounted at the top of the guide mounting cylinder 21, a hydraulic cylinder 26 is vertically mounted at the center of the driving mounting top plate 25, and a crushing mechanism is mounted inside the guide mounting cylinder 21 and includes a crushing base 27, a transition spring 28 and a crushing top seat 29 which are sequentially mounted from bottom to top; the drive mounting top plate 25 is centrally provided with a guide mounting hole 251, and the piston rod of the hydraulic cylinder 26 passes through the guide mounting hole 251 to be fixedly connected with the crushing top seat 29.
As shown in fig. 6, the inboard external screw thread section of thick bamboo 211 that is equipped with in the bottom of the direction installation section of thick bamboo 21, the cover 22 top is collected to the raw materials is circular opening, the cover 22 bottom is collected to the raw materials is square opening, the cover 22 top outside is collected to the raw materials is equipped with the internal screw thread section of thick bamboo 221 with external screw thread section of thick bamboo 211 matched with, the cover 22 bottom is collected to the raw materials equipartition all around has four location screw 223 that are the rectangle and distribute, there is first spacing draw-in groove 222 along the straight line.
As shown in fig. 7, the crushing base 27 includes a crushing base plate 271 and a guide sliding column 272 vertically disposed at the center of the crushing base plate 271, and rotation-preventing protrusions 273 are uniformly distributed on the periphery of the guide sliding column 272; the transition spring 28 is arranged outside the guide sliding column 272; the crushing top seat 29 comprises a crushing top plate 291 and a sliding pressure column 292 vertically arranged at the center of the bottom of the crushing top plate 291, a guide sliding hole 293 matched with the guide sliding column 272 is formed in the center of the bottom of the sliding pressure column 292, anti-rotation clamping grooves 294 matched with the anti-rotation protrusions 273 are uniformly distributed on the inner side of the guide sliding hole 293, the bottom of the transition spring 28 is in contact connection with the crushing bottom plate 271, and the top of the transition spring 28 is in contact connection with the sliding pressure column 292.
As shown in fig. 8, the crushing and separating mechanism 24 includes a plurality of separating members 241 uniformly distributed at the bottom of the raw material collecting cover 22, and the plurality of separating members 241 form a criss-cross net structure.
As shown in fig. 9, the separating element 241 includes a central thin rod 242, two ends of the central thin rod 242 are symmetrically provided with mounting and positioning rods 243 matching with the first limiting slot 222, and the outer ends of the mounting and positioning rods 243 are provided with limiting balls 244.
As shown in fig. 10, the crushing collecting seat 23 includes a square connecting block 231 fixed at the bottom of the raw material collecting cover 22, a second flow guide pipe 235 communicated with the first flow guide pipe 116 is vertically arranged at the center of the bottom of the square connecting block 231, four positioning through holes 233 corresponding to the positioning screw holes 223 are uniformly distributed around the top surface of the square connecting block 231, a second limiting clamping groove 232 corresponding to the first limiting clamping groove 222 is uniformly distributed between two adjacent positioning through holes 233, a crushing collecting groove 234 with a wide top and a narrow bottom is arranged at the center of the top surface of the square connecting block 231, and the bottom of the crushing collecting groove 234 is communicated with the second flow guide pipe.
As shown in fig. 11, the stirring mechanism 3 includes a grinding enclosure 31 and a feeding collecting cover 32 fixedly installed on the top of the grinding enclosure 31, the bottom of the grinding enclosure 31 is vertically installed with a stirring member 34, and the middle of the grinding enclosure 31 is installed with a grinding mechanism 33.
As shown in fig. 12, the grinding mechanism 33 includes horizontal grinding mechanisms 331 uniformly distributed along the vertical direction, the horizontal grinding mechanisms 331 include rotary grinding assemblies sequentially mounted along the horizontal linear direction, the rotary grinding assemblies include two grinding rotating shafts 332 with opposite rotation directions, and two rotary mounting shafts 333 are symmetrically disposed at two ends of the grinding rotating shafts 332.
As shown in fig. 13, the top of the feeding collecting cover 32 is a circular opening, the bottom of the feeding collecting cover 32 is a square opening, the grinding enclosure 31 is a square tube structure, and the front and rear sides of the grinding enclosure 31 are uniformly provided with rotating mounting holes 311 matching with the rotating mounting shaft 333.
As shown in fig. 14, the stirring element 34 includes a stirring cylinder 341 and a stirring and collecting cover 342 disposed at the top of the stirring cylinder 341, six oblique diversion pipes 343 disposed obliquely are uniformly distributed at the bottom of the stirring cylinder 341 along the circumferential direction, the top of the oblique diversion pipes 343 is communicated with the stirring cylinder 341, and the bottom of the oblique diversion pipes 343 is communicated with the bracing pipes 117; a stirring mounting column 344 is arranged at the center of the inner bottom surface of the stirring cylinder 341, a stirring mounting hole 345 is arranged at the center of the stirring mounting column 344, and a stirrer is mounted in the stirring mounting hole 345; the top of the stirring and collecting cover 342 is a square opening, and the bottom of the stirring and collecting cover 342 is a round opening.
Wherein, grind between enclosing cover 31 and the stirring and collect cover 342, grind and enclose and collect and cover 32 between all link to each other through the welding between cover 31 and the feeding, collect and cover 22 and square connecting block 231 between link to each other through bolt fastening for the raw materials, all install the check valve in the middle of second honeycomb duct 235, the water conservancy diversion pipe chute 343.
In the preparation device, the crushing mechanism 2 is used for primary crushing in the preparation method, the mixing and boiling mechanism 1 is used for soaking, primary boiling and secondary boiling in the preparation method, the grinding mechanism 33 is used for secondary crushing in the preparation method, and the stirring piece 34 is used for remixing in the preparation method.
The analgesic liquid medicine has the advantages of quick drug effect exertion, no toxic or side effect on liver, analgesic effect and treatment effect, no adverse stimulation to skin, obvious analgesic effect and definite analgesic effect, is more convenient to use than oral analgesic and injection analgesic, has simple preparation method flow and convenient preparation, and provides better guarantee for the quality of the analgesic liquid medicine.
In the description herein, references to the description of "one embodiment," "an example," "a specific example" or the like are intended to mean that a particular feature, structure, material, or characteristic described in connection with the embodiment or example is included in at least one embodiment or example of the invention. In this specification, the schematic representations of the terms used above do not necessarily refer to the same embodiment or example. Furthermore, the particular features, structures, materials, or characteristics described may be combined in any suitable manner in any one or more embodiments or examples.
The foregoing shows and describes the general principles, essential features, and advantages of the invention. It will be understood by those skilled in the art that the present invention is not limited to the embodiments described above, which are described in the specification and illustrated only to illustrate the principle of the present invention, but that various changes and modifications may be made therein without departing from the spirit and scope of the present invention, which fall within the scope of the invention as claimed.
Claims (4)
1. A preparation device of external analgesic liquid medicine is characterized in that: the device comprises a mixing and boiling mechanism (1) and six crushing mechanisms (2) which are uniformly distributed on the edge of the top of the mixing and boiling mechanism (1) along the circumferential direction, wherein a stirring mechanism (3) is vertically arranged in the center of the top of the mixing and boiling mechanism (1);
the mixed boiling mechanism (1) comprises a supporting installation seat (11) and a boiling collection seat (14) fixedly installed at the bottom of the supporting installation seat (11), and an outer heating ring (12) and an inner heating ring (13) are respectively installed inside the supporting installation seat (11); the supporting and mounting seat (11) comprises an annular top plate (111), an outer surrounding cylinder (112) is vertically arranged on the outer side of the bottom of the annular top plate (111), an inner surrounding cylinder (113) is vertically arranged on the inner side of the bottom of the annular top plate (111), a first annular clamping groove (114) is formed in the middle of the inner wall of the outer surrounding cylinder (112), a second annular clamping groove (115) is formed in the middle of the inner wall of the inner surrounding cylinder (113), an outer heating ring (12) is installed in the first annular clamping groove (114), an inner heating ring (13) is installed in the second annular clamping groove (115), a flow guide cavity is formed between the outer surrounding cylinder (112) and the inner surrounding cylinder (113), six first flow guide pipes (116) vertically communicated with the flow guide cavity are uniformly distributed on the surface of the annular top plate (111) along the circumferential direction, and an inclined; an annular collecting tank (141) is arranged on the surface of the boiling collecting seat (14);
the crushing mechanism (2) comprises a guide mounting cylinder (21) and a raw material collecting cover (22) fixedly mounted at the bottom of the guide mounting cylinder (21), a crushing collecting seat (23) is fixedly mounted at the bottom of the raw material collecting cover (22), a crushing separating mechanism (24) is horizontally mounted between the raw material collecting cover (22) and the crushing collecting seat (23), a driving mounting top plate (25) is horizontally mounted at the top of the guide mounting cylinder (21), a hydraulic cylinder (26) is vertically mounted in the center of the driving mounting top plate (25), and a crushing mechanism is mounted inside the guide mounting cylinder (21) and comprises a crushing base (27), a transition spring (28) and a crushing top seat (29) which are sequentially mounted from bottom to top; a guide mounting hole (251) is formed in the center of the drive mounting top plate (25), and a piston rod of the hydraulic cylinder (26) penetrates through the guide mounting hole (251) to be fixedly connected with the crushing top seat (29);
an external thread cylinder (211) is arranged on the inner side of the bottom of the guide mounting cylinder (21), the top of the raw material collecting cover (22) is a circular opening, the bottom of the raw material collecting cover (22) is a square opening, an internal thread cylinder (221) matched with the external thread cylinder (211) is arranged on the outer side of the top of the raw material collecting cover (22), four positioning screw holes (223) which are distributed in a rectangular shape are uniformly distributed on the periphery of the bottom of the raw material collecting cover (22), and first limiting clamping grooves (222) are uniformly distributed between every two adjacent positioning screw holes (223) along the linear direction;
the crushing base (27) comprises a crushing bottom plate (271) and a guide sliding column (272) vertically arranged in the center of the crushing bottom plate (271), and anti-rotation protrusions (273) are uniformly distributed on the periphery of the guide sliding column (272); a transition spring (28) is arranged on the outer side of the guide sliding column (272); the crushing top seat (29) comprises a crushing top plate (291) and a sliding pressure column (292) vertically arranged at the center of the bottom of the crushing top plate (291), a guide sliding hole (293) matched with the guide sliding column (272) is formed in the center of the bottom of the sliding pressure column (292), anti-rotation clamping grooves (294) matched with the anti-rotation protrusions (273) are uniformly distributed on the inner side of the guide sliding hole (293), the bottom of the transition spring (28) is in contact connection with the crushing bottom plate (271), and the top of the transition spring (28) is in contact connection with the sliding pressure column (292);
the crushing and separating mechanism (24) comprises a plurality of separating pieces (241) which are uniformly distributed at the bottom of the raw material collecting cover (22), and the separating pieces (241) form a criss-cross net-shaped structure;
the separating piece (241) comprises a central thin rod (242), two ends of the central thin rod (242) are symmetrically provided with mounting and positioning rods (243) matched with the first limiting clamping grooves (222), and the outer ends of the mounting and positioning rods (243) are provided with limiting balls (244);
the crushing and collecting base (23) comprises a square connecting block (231) fixed at the bottom of the raw material collecting cover (22), a second guide pipe (235) communicated with the first guide pipe (116) is vertically arranged in the center of the bottom of the square connecting block (231), four positioning through holes (233) corresponding to the positioning screw holes (223) are uniformly distributed on the periphery of the top surface of the square connecting block (231), a second limiting clamping groove (232) corresponding to the first limiting clamping groove (222) is uniformly distributed between every two adjacent positioning through holes (233), a crushing and collecting tank (234) with a wide upper part and a narrow lower part is arranged in the center of the top surface of the square connecting block (231), and the bottom of the crushing and collecting tank (234) is communicated with the second guide;
the stirring mechanism (3) comprises a grinding surrounding cover (31) and a feeding collecting cover (32) fixedly arranged at the top of the grinding surrounding cover (31), a stirring piece (34) is vertically arranged at the bottom of the grinding surrounding cover (31), and a grinding mechanism (33) is arranged in the middle of the grinding surrounding cover (31);
the grinding mechanism (33) comprises horizontal grinding mechanisms (331) which are uniformly distributed along the vertical direction, the horizontal grinding mechanisms (331) comprise rotary grinding assemblies which are sequentially installed along the horizontal linear direction, each rotary grinding assembly consists of two grinding rotating shafts (332) with opposite rotation directions, and two rotary installation shafts (333) are symmetrically arranged at two ends of each grinding rotating shaft (332);
the top of the feeding collection cover (32) is a circular opening, the bottom of the feeding collection cover (32) is a square opening, the grinding enclosure cover (31) is of a square barrel structure, and rotary mounting holes (311) matched with the rotary mounting shafts (333) are uniformly distributed in the front side and the rear side of the grinding enclosure cover (31);
the stirring piece (34) comprises a stirring cylinder (341) and a stirring and collecting cover (342) arranged at the top of the stirring cylinder (341), six inclined flow guide pipes (343) are uniformly distributed at the bottom of the stirring cylinder (341) along the circumferential direction, the top of each inclined flow guide pipe (343) is communicated with the stirring cylinder (341), and the bottom of each inclined flow guide pipe (343) is communicated with the inclined bracing pipe (117); a stirring mounting column (344) is arranged at the center of the inner bottom surface of the stirring cylinder (341), a stirring mounting hole (345) is arranged at the center of the stirring mounting column (344), and a stirrer is arranged in the stirring mounting hole (345); the top of the stirring and collecting cover (342) is a square opening, and the bottom of the stirring and collecting cover (342) is a round opening.
2. The apparatus for preparing an analgesic liquid medicine for external use according to claim 1, wherein: the grinding surrounding cover (31) is connected with the stirring collecting cover (342) and the grinding surrounding cover (31) is connected with the feeding collecting cover (32) through welding.
3. The apparatus for preparing an analgesic liquid medicine for external use according to claim 1, wherein: the raw material collecting cover (22) is fixedly connected with the square connecting block (231) through bolts.
4. The apparatus for preparing an analgesic liquid medicine for external use according to claim 1, wherein: and one-way valves are arranged between the second flow guide pipe (235) and the flow guide inclined pipe (343).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810999194.9A CN108969664B (en) | 2018-08-30 | 2018-08-30 | External analgesic liquid medicine and preparation method and preparation device thereof |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201810999194.9A CN108969664B (en) | 2018-08-30 | 2018-08-30 | External analgesic liquid medicine and preparation method and preparation device thereof |
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| Publication Number | Publication Date |
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| CN108969664A CN108969664A (en) | 2018-12-11 |
| CN108969664B true CN108969664B (en) | 2021-02-02 |
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| CN114178241B (en) * | 2021-11-29 | 2022-11-25 | 九江市彭泽县宏兴油脂有限公司 | Circulation belt cleaning device of rape seed |
Citations (3)
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| CN105998630A (en) * | 2016-07-19 | 2016-10-12 | 艾尼·图尔荪 | Traditional Chinese medicine preparation for regulating Qi and blood circulation, preparation method and dedicated device |
| CN106511969A (en) * | 2016-11-14 | 2017-03-22 | 南京汉尔斯生物科技有限公司 | A composite medicinal preparation used for treating gout and a preparing method thereof |
| CN107648046A (en) * | 2017-09-29 | 2018-02-02 | 武汉马腾科技发展有限公司 | A kind of quick decoction of Chinese medicine decocts device with mill |
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Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105998630A (en) * | 2016-07-19 | 2016-10-12 | 艾尼·图尔荪 | Traditional Chinese medicine preparation for regulating Qi and blood circulation, preparation method and dedicated device |
| CN106511969A (en) * | 2016-11-14 | 2017-03-22 | 南京汉尔斯生物科技有限公司 | A composite medicinal preparation used for treating gout and a preparing method thereof |
| CN107648046A (en) * | 2017-09-29 | 2018-02-02 | 武汉马腾科技发展有限公司 | A kind of quick decoction of Chinese medicine decocts device with mill |
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