CN106344804A - Traditional Chinese medicine composition for treating bone fracture, and preparation method thereof - Google Patents
Traditional Chinese medicine composition for treating bone fracture, and preparation method thereof Download PDFInfo
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- 239000003814 drug Substances 0.000 title claims abstract description 41
- 239000000203 mixture Substances 0.000 title claims abstract description 41
- 238000002360 preparation method Methods 0.000 title claims description 17
- 208000010392 Bone Fractures Diseases 0.000 title abstract description 26
- 238000003756 stirring Methods 0.000 claims abstract description 39
- 239000002994 raw material Substances 0.000 claims abstract description 8
- 235000003143 Panax notoginseng Nutrition 0.000 claims abstract description 7
- 241000180649 Panax notoginseng Species 0.000 claims abstract description 7
- 239000008187 granular material Substances 0.000 claims abstract description 6
- 241001619461 Poria <basidiomycete fungus> Species 0.000 claims abstract description 5
- 239000000463 material Substances 0.000 claims description 32
- 238000005266 casting Methods 0.000 claims description 30
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 24
- 239000012567 medical material Substances 0.000 claims description 16
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 15
- 238000002156 mixing Methods 0.000 claims description 14
- 239000002245 particle Substances 0.000 claims description 14
- 239000002671 adjuvant Substances 0.000 claims description 9
- 230000033228 biological regulation Effects 0.000 claims description 8
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Classifications
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- A61K36/18—Magnoliophyta (angiosperms)
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- A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
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- B01F27/00—Mixers with rotary stirring devices in fixed receptacles; Kneaders
- B01F27/05—Stirrers
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- B01F27/806—Mixers with rotary stirring devices in fixed receptacles; Kneaders with stirrers rotating about a substantially vertical axis wherein the stirrers or the receptacles are moved in order to bring them into operative position; Means for fixing the receptacle with vertical displacement of the stirrer, e.g. in combination with means for pivoting the stirrer about a vertical axis in order to co-operate with different receptacles
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- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation or decoction
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- A61K2236/30—Extraction of the material
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- B—PERFORMING OPERATIONS; TRANSPORTING
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Abstract
The invention relates to a traditional Chinese medicine composition for treating bone fracture. The traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 20-40 parts of pteris vittata, 10-20 parts of mengtzu falsehellebore roots, 25-35 parts of goodyera roots, 20-30 parts of threeleaf loosestrife herbs, 10-20 parts of radix salviae miltiorrhizae, 20-30 parts of fructus psoraleae, 10-20 parts of radix notoginseng, 10-30 parts of poria, 5-15 parts of gynostemma pentaphyllum, and 5-15 parts of radix glycyrrhizae, which are mixed by adopting a specific granule stirring machine. The traditional Chinese medicine composition is good in content uniformity and can treat bone fracture.
Description
Technical field
The invention belongs to technical field of Chinese medicines, treat fracture Chinese medicine composition particularly to one kind.
Background technology
Fracture is that the seriality of bone structure ruptures wholly or in part.Be more common in child and old people, young people also when
There is generation.Patient is often a position fracture, and minority is multiple fracture.Through appropriately processing in time, most patients can recover former
The function of coming, a few patients can leave different degrees of sequela.Treatment fracture product variety in the market is various, but
Mostly all made with medicine, large side effects or poor taste, uniformity of dosage units is bad, usually produces when clinically patient takes
Side effect.
Content of the invention
In order to overcome the deficiencies in the prior art, the present invention is changed to adjuvant screening, process optimization and equipment by lot of experiments
Enter, there is provided one kind treats fracture Chinese medicine composition, uniformity of dosage units is good, preparation process is simple.
The object of the present invention is achieved like this:
One kind treats fracture Chinese medicine composition, and it is prepared from by following raw materials in part by weight proportioning: Herba pteridis vittatae 20-40 part,
Little palm fibre bag 10-20 part, Radix Coodyerae schlechtendalianae 25-35 part, Herba Lysimachiae Insigniss 20-30 part, Radix Salviae Miltiorrhizae 10-20 part, Fructus Psoraleae 20-30 part, Radix Notoginseng 10-
20 parts, Poria 10-30 part, Herb Gynostemmae Pentaphylli 5-15 part, Radix Glycyrrhizae 5-15 part.
Described treatment fracture Chinese medicine composition, it is prepared from by following raw materials in part by weight proportioning: 30 parts of Herba pteridis vittatae, little palm fibre
15 parts of bag, 30 parts of Radix Coodyerae schlechtendalianae, 5 parts of Herba Lysimachiae Insigniss, 15 parts of Radix Salviae Miltiorrhizae, 25 parts of Fructus Psoraleae, 15 parts of Radix Notoginseng, 20 parts of Poria, Herb Gynostemmae Pentaphylli 10
Part, 10 parts of Radix Glycyrrhizae.
Described treatment fracture Chinese medicine composition, dosage form is granule, tablet, capsule.
Described treatment fracture Chinese medicine composition, preparation method step is: takes above-mentioned medical material to merge, adds water to cook twice, close
And decocting liquid, when being concentrated into 65 DEG C, relative density is 1.10-1.20, plus ethanol makes the percent by volume of alcohol content reach 65-85%, stirs
Mix, standing, filter, filtrate reduced in volume to relative density when 65 DEG C is 1.20-1.30 and reclaims ethanol, obtains concentrated solution, will be dense
Contracting liquid be spray-dried, add adjuvant, mix homogeneously in Particle mixer, pelletize according to a conventional method, make capsule, tablet,
Granule.
Described treatment fracture Chinese medicine composition, in preparation method, decocting condition is: the 8- adding water for the first time as medical material weight
12 times amount, decoct 1-2h, the 6-10 times amount adding water for the second time as medical material weight, decoct 1-2h.
Described treatment fracture Chinese medicine composition, in preparation method, spray drying condition is: inlet temperature is 100-120 DEG C,
Leaving air temp is 80-90 DEG C, and temperature of charge is 70-90 DEG C, and atomizing pressure is 0.2-0.4 MPa, and spray velocity is 5-10ml/s.
Described treatment fracture Chinese medicine composition, preparation method comprises the following steps: to take above-mentioned raw materials medicine and adjuvant to be placed in
Pulverize in disintegrating apparatus；Mix homogeneously in Particle mixer, pelletizes according to a conventional method, tabletting, packs to obtain finished product.
Described treatment fracture Chinese medicine composition, Particle mixer in preparation method, including base, it is arranged on described base
Stirring cylinder, be provided with stirring motor in described base, in the main shaft of described stirring motor and the diapire of described stirring cylinder
The heart is connected, and is provided with stirring mast on the diapire in described mixing drum body, vertically uniform in the side wall of described stirring cylinder
It is provided with least two cavitys, be provided with l type material casting plate in described cavity, the corner of described l type material casting plate is by rotary shaft even
It is connected in cavity and the outboard end of described l type material casting plate stretches in described mixing drum body, be provided with material casting in described cavity and drive
Motor, is provided with the main shaft of described material casting motor and compresses eccentric, the medial extremity of described l type material casting plate and described cavity
Side wall between be provided with stress spring, the described wheel side compressing eccentric be pressed on l type material casting plate medial extremity and cavity side walls it
Between, described base is additionally provided with support rod, regulation vertical slot is provided with described support rod, in described regulation vertical slot, be provided with liter
Fall block, is provided with lift cylinder between described elevator and described regulation vertical slot, is provided with electric rotating machine in described elevator,
The main shaft of described electric rotating machine is provided with column spinner, described column spinner stretch into when described elevator declines in described mixing drum and
Described column spinner is staggered setting with stirring mast.
Described treatment fracture Chinese medicine composition, is provided with sealing gasket at the opening of described cavity, described rotary shaft is wrapped in institute
State in sealing gasket.
Described treatment fracture Chinese medicine composition, described column spinner is provided with stirring palpus, on the roof of described stirring cylinder
It is provided with charging aperture and feeding detection mouth.
Application in preparation treatment fracture for the described treatment fracture Chinese medicine composition.
Herba pteridis vittatae, Latin entitled pteris vittata l, is fern Pteridaceae Pteris plant Herba pteridis vittatae.Heat clearing away
Dampness removing, removing toxic substances and promoting subsidence of swelling.For hygropyretic dysentery stomachache.Centipete bite, scabies, innominate toxic swelling are controlled in external.The present invention is with all herbal medicine.
Little palm fibre is wrapped as Liliaceae Li Lu platymiscium Mengzi Li Lu veratrum mengtzeanum loes.f., with root and complete
Grass is used as medicine.Autumn harvests, and dries respectively.Promoting blood circulation to remove blood stasis, hemostatic analgesia, emetic diuretic.For traumatic injury, fracture, edema；Outward
With controlling traumatic hemorrhage.The present invention is with all herbal medicine.
Radix Coodyerae schlechtendalianae is rhizome and the root of the big Herba goodyearae repentis of orchid or little Herba goodyearae repentis.Kidney invigorating and YANG supporting.Control deficiency syndrome.
Herba Lysimachiae Insigniss are the Herb of Ofthe Primulaceae SANYE Herba lysimachiae capillipedis, and whole year can adopt, and has expelling wind and removing dampness, relaxing muscles and tendons to promote blood circulation is equivalent
With.
Compared with prior art, FUFANG LIXUEPING PIAN according to the present invention has a technique effect beneficial as follows:
(1) uniformity of dosage units is good.(2) preparation process is simple, structure is simple, is provided with l type material casting plate, and it passes through when using
Compressing eccentric cooperation stress spring can make l type material casting plate rotate centered on rotary shaft, thus by mixing drum interior part medicine
Thing throws to the center of mixing drum, and is additionally provided with column spinner, by the reverse rotation of column spinner and mixing drum, can will be in l
The bottom medicine agitation of type material casting plate, the medicine decline such that it is able to make l type material casting back is stirred by column spinner, thus significantly
Improve stirring efficiency, and be not easy occur stirring dead angle, solve conventional art medicine agitating device stirring have dead angle and
The low technical deficiency of stirring efficiency, stability in use is good and strong applicability.(3) Herba pteridis vittatae of the present invention, little palm fibre bag, Radix Coodyerae schlechtendalianae,
Herba Lysimachiae Insigniss clearing away heat-damp and promoting diuresis, removing toxic substances and promoting subsidence of swelling is monarch drug, and Radix Salviae Miltiorrhizae, Fructus Psoraleae, Radix Notoginseng, Poria blood circulation promoting and blood stasis dispelling are ministerial drug, Herb Gynostemmae Pentaphylli, Radix Glycyrrhizae
For adjuvant, there is treatment fracture effect jointly.
Brief description
Fig. 1 is the structural representation of Particle mixer
Specific embodiment
Form is described in further detail to the above of the present invention again by the following examples, but should not manage this
Solve the scope for the above-mentioned theme of the present invention and be only limitted to Examples below, all belonged to based on the technology that the above of the present invention is realized
In the scope of the present invention.
1st, combine specific embodiment, the present invention is further described as follows:
According to the form below, listed weight proportion weighs needed raw material of the present invention, unit: g
| Joy centipede grass | Little palm fibre bag | Radix Coodyerae schlechtendalianae | Herba Lysimachiae Insigniss | Radix Salviae Miltiorrhizae | Fructus Psoraleae | Radix Notoginseng | Poria | Herb Gynostemmae Pentaphylli | Radix Glycyrrhizae | |
| Embodiment 1 | 20 | 20 | 25 | 30 | 10 | 30 | 10 | 30 | 5 | 15 |
| Embodiment 2 | 30 | 15 | 30 | 25 | 15 | 25 | 15 | 20 | 10 | 10 |
| Embodiment 3 | 40 | 10 | 35 | 20 | 20 | 20 | 20 | 10 | 15 | 5 |
2. prepare embodiment
Taking upper table Central Plains material proportioning as a example, comprise the following steps:
Embodiment 1: weigh medical material by upper table and mix, add water to cook twice, 8 times adding water for the first time as medical material weight
Amount, decocts 1h, 6 times amount adding water for the second time as medical material weight, decocts 1h, collecting decoction, filtration, filtrate is concentrated into relative density
1.10 (65 DEG C), plus ethanol in proper amount makes alcohol content (volume fraction) reach 65%, stirring, stands 24 hours, filtration, filtrate reclaims second
Alcohol is simultaneously concentrated into the extractum of relative density 1.20 (65 DEG C), and spray-dried (condition is 100 DEG C for inlet temperature, leaving air temp
For 80 DEG C, temperature of charge is 70 DEG C, and atomizing pressure is 0.2 MPa, and spray velocity is 5ml/s.), it is ground into dry extract, add
Adjuvant, mix homogeneously in Particle mixer, pelletize according to a conventional method, make granule.
Above-mentioned Particle mixer, is shown in Fig. 1, including including base 1, is arranged on the stirring cylinder 2 on described base 1, in institute
State and in base 1, be provided with stirring motor 3, the main shaft of described stirring motor 3 is connected with the bottom wall central of described stirring cylinder 2,
Diapire in described stirring cylinder 2 is provided with stirring mast 4, is vertically uniformly provided with least in the side wall of described stirring cylinder 2
Two cavitys 5, are provided with l type material casting plate 6 in described cavity 5, and the corner of described l type material casting plate 6 is connected to by rotary shaft 7
In cavity 5 and the outboard end of described l type material casting plate 6 stretches in described stirring cylinder 2, it is provided with material casting in described cavity 5 and drives
Motor 8, is provided with the main shaft of described material casting motor 8 and compresses eccentric 9, the medial extremity of described l type material casting plate 6 with described
Be provided with stress spring 10 between the side wall of cavity 5, the described wheel side compressing eccentric 9 be pressed on l type material casting plate 6 medial extremity with recessed
Between the side wall of chamber 5, when using, the wheel side activity compressing eccentric is pressed on the end of l type material casting plate, so that l type material casting
The end of plate is rotated centered on rotary shaft and stretches stress spring makes it store power, when rotating to the concave edge compressing eccentric, l
The end of type material casting plate resets under the pulling of stress spring, so that medical material is thrown to and stirred by the plate body movement being in mixing drum
Mix the center of cylinder, described base 1 is additionally provided with support rod 11, regulation vertical slot 12 is provided with described support rod 11, described
Adjust in vertical slot 12 and be provided with elevator 13, between described elevator 13 and described regulation vertical slot 12, be provided with lift cylinder 14,
It is provided with electric rotating machine 15 in described elevator 13, column spinner 16, described column spinner are provided with the main shaft of described electric rotating machine 15
16 stretch in described mixing drum 2 when described elevator 13 declines and described column spinner 16 and stirring mast 4 stagger setting.In order to
Facilitate column spinner to enter mixing drum, the top cover of mixing drum can be opened after loading column spinner, then top cover is covered.
It is provided with sealing gasket 17 at the opening of described cavity 5, described rotary shaft is wrapped in described sealing gasket.
Described column spinner is provided with stirring palpus 18, is provided with charging aperture 19 and feeding detection on the roof of described stirring cylinder
Mouth 20.Using stirring palpus, because it is flexible material, so not interfering with the normal material casting operation of l type material casting plate.
Embodiment 2: weigh medical material by upper table and mix, add water to cook twice, 10 times adding water for the first time as medical material weight
Amount, decocts 1.5h, 8 times amount adding water for the second time as medical material weight, decocts 1.5h, collecting decoction, filtration, filtrate is concentrated into relatively
Density 1.15 (65 DEG C), plus ethanol in proper amount makes alcohol content (volume fraction) reach 75%, stirring, stands 24 hours, filtration, filtrate is returned
Receive ethanol and be concentrated into the extractum of relative density 1.25 (65 DEG C), spray-dried (condition is 120 DEG C for inlet temperature, air-out
Temperature is 90 DEG C, and temperature of charge is 80 DEG C, and atomizing pressure is 0.3 MPa, and spray velocity is 7.5/s.), it is ground into dry extract,
Add adjuvant, mix homogeneously in Particle mixer, pelletize according to a conventional method, make tablet.
Particle mixer is ibid.
Embodiment 3: weigh medical material by upper table and mix, add water to cook twice, 10 times adding water for the first time as medical material weight
Amount, decocts 1.5h, 8 times amount adding water for the second time as medical material weight, decocts 1.5h, collecting decoction, filtration, filtrate is concentrated into relatively
Density 1.15 (65 DEG C), plus ethanol in proper amount makes alcohol content (volume fraction) reach 75%, stirring, stands 24 hours, filtration, filtrate is returned
Receive ethanol and be concentrated into the extractum of relative density 1.25 (65 DEG C), spray-dried (condition is 120 DEG C for inlet temperature, air-out
Temperature is 90 DEG C, and temperature of charge is 90 DEG C, and atomizing pressure is 0.4 MPa, and spray velocity is 7.5/s.), it is ground into dry extract,
Add adjuvant, mix homogeneously in Particle mixer, pelletize according to a conventional method, make capsule.
Particle mixer is ibid.
Comparative example 4: make tablet with embodiment 2, using general Particle mixer.
3. uniformity of dosage units experiment
Content and content uniformity determination all by Chinese Pharmacopoeia two method operations of version in 2010, measures in Tablets
The content of TANSHINONES iia.The chromatographic column that high performance liquid chromatography adopts is kromasilc18 (250mm × 4.6mm, 5 μm), stream
Move and mutually adopt methanol-water (73/27), column temperature is 25 DEG C, and Detection wavelength is 270 nanometers, and flow velocity is 1 milliliter per minute.Take respectively
Ten tablets of embodiment 2 and comparative example 4 carry out the assay of TANSHINONES iia, find the TANSHINONES in embodiment 2
Iia content is 0.16-0.18%, and the TANSHINONES iia content in comparative example 4 is 0.03-0.32%, illustrates that embodiment 2 is made
Piece agent uniformity of dosage units is good.
4. the pharmacodynamic study of the impact of the bone density of pair laboratory animal
Sample preparation: prepare test specimen by above-described embodiment 1, precious strong SHENGU JIAONANG, Shandong meeting elixir industry group is limited
Company, lot number: 20140511.Retinoic acid piece, Shandong Liang Fu pharmaceutical Co. Ltd, lot number: 150120
Animal: w istar rat, male, body weight 180-240g, Shanghai Slac Experimental Animal Co., Ltd. provides.
Experiment packet and the foundation of model rat with osteoporosis: take normal w istar rat 30 to be only randomly divided into 5 groups, take
Wherein 6 is ns group；Take wherein 6 to be only used as model group, press Retinoic acid 70mg/kg gavage two weeks merely；Wherein 6 are taken to be only used as treasure
Strong SHENGU JIAONANG matched group；Remaining 12 rats are as the high low dose group of the present invention.As ZHENMUSHENGU JIAONANG matched group and
High and low dose group of the present invention is gavaged by the dosage of 70mg/kg and gavages corresponding medicine while Retinoic acid, withdraws after gavaging two weeks
Retinoic acid continues two weeks and measures indices.Rat sacrificed by decapitation, takes its femur by group arrangement, using the shooting of x- line mammary gland
Mating plate produced by machine, with black and white densimeter on the greater trochanter of femur, femoral head, neck of femur, intertrochanteric line and lower 5 of intertrochanteric line
Position fixed point measures and records bone density value.
Impact to rat bone density
Compare with model group, * 1p < 0.01, * 2p < 0.05
Test result indicate that, the present invention is compared with model group, has significant difference, illustrates that the present invention can improve bone close
Degree, treatment fracture, and also effect is better than precious strong SHENGU JIAONANG.
5. model case
Case 1: fourth, man, 50 years old.Injured clinical diagnosises are right lower extremity fracture in hospital, and the therapeutic scheme of employing is as follows:
Take the above embodiment of the present invention 1 preparation clinical trial sample, each 10g, daily 2 times, be discharged from hospital after recovery after serveing on six weeks.
Case 2: Wang, female, 44 years old.Patient injury is in hospital, and clinical diagnosises scratch bone fracture for left chi, take the present invention above-mentioned
Embodiment 1 prepares clinical trial sample, each 10g, is discharged from hospital after recovery after serveing on two months.
Claims (10)
1. one kind treats fracture Chinese medicine composition it is characterised in that it is prepared from by following raw materials in part by weight proportioning: Herba pteridis vittatae
20-40 part, little palm fibre bag 10-20 part, Radix Coodyerae schlechtendalianae 25-35 part, Herba Lysimachiae Insigniss 20-30 part, Radix Salviae Miltiorrhizae 10-20 part, Fructus Psoraleae 20-30
Part, Radix Notoginseng 10-20 part, Poria 10-30 part, Herb Gynostemmae Pentaphylli 5-15 part, Radix Glycyrrhizae 5-15 part.
2. treatment fracture Chinese medicine composition as claimed in claim 1 is it is characterised in that it is prepared by following raw materials in part by weight proportioning
Form: 30 parts of Herba pteridis vittatae, 15 parts of little palm fibre bag, 30 parts of Radix Coodyerae schlechtendalianae, 5 parts of Herba Lysimachiae Insigniss, 15 parts of Radix Salviae Miltiorrhizae, 25 parts of Fructus Psoraleae, Radix Notoginseng 15
Part, 20 parts of Poria, 10 parts of Herb Gynostemmae Pentaphylli, 10 parts of Radix Glycyrrhizae.
3. treatment fracture Chinese medicine composition as claimed in claim 1 is it is characterised in that dosage form is granule, tablet, capsule.
4. treatment fracture Chinese medicine composition as claimed in claim 1 is it is characterised in that preparation method step is: takes above-mentioned medical material to close
And, add water to cook twice, collecting decoction, when being concentrated into 65 DEG C, relative density is 1.10-1.20, plus ethanol makes the volume of alcohol content
Percentage ratio reaches 65-85%, stirring, and standing filters, and filtrate reduced in volume to relative density when 65 DEG C is 1.20-1.30 and reclaims
Ethanol, obtains concentrated solution, and concentrated solution is spray-dried, and adds adjuvant, mix homogeneously in Particle mixer, makes according to a conventional method
Grain, makes capsule, tablet, granule.
5. treatment fracture Chinese medicine composition as claimed in claim 4 it is characterised in that in preparation method decocting condition be: the
The 8-12 times amount once adding water as medical material weight, decocts 1-2h, the 6-10 times amount adding water for the second time as medical material weight, decocts 1-
2h.
6. treatment fracture Chinese medicine composition as claimed in claim 4 is it is characterised in that spray drying condition in preparation method
For: inlet temperature is 100-120 DEG C, and leaving air temp is 80-90 DEG C, and temperature of charge is 70-90 DEG C, and atomizing pressure is 0.2-0.4
MPa, spray velocity is 5-10ml/s.3. treatment fracture Chinese medicine composition as claimed in claim 1 is it is characterised in that preparation side
Method comprises the following steps: to take above-mentioned raw materials medicine and adjuvant to be placed in disintegrating apparatus and pulverize；Mix homogeneously in Particle mixer,
Pelletize according to a conventional method, tabletting, pack to obtain finished product.
7. treatment fracture Chinese medicine composition as claimed in claim 4 is it is characterised in that Particle mixer in preparation method, the bottom of including
Seat, is arranged on the stirring cylinder on described base, is provided with stirring motor, the main shaft of described stirring motor and institute in described base
The bottom wall central stating stirring cylinder is connected, and is provided with stirring mast, in described mixing drum on the diapire in described mixing drum body
Vertically it is uniformly provided with least two cavitys in the side wall of body, be provided with l type material casting plate in described cavity, described l type material casting plate
Corner is connected in cavity by rotary shaft and the outboard end of described l type material casting plate stretches in described mixing drum body, described
It is provided with material casting motor in cavity, the main shaft of described material casting motor is provided with and compresses eccentric, described l type material casting plate
Medial extremity and the side wall of described cavity between be provided with stress spring, the described wheel side compressing eccentric is pressed on l type material casting plate
Between medial extremity and cavity side walls, described base is additionally provided with support rod, regulation vertical slot is provided with described support rod, in institute
State in regulation vertical slot and be provided with elevator, be provided with lift cylinder between described elevator and described regulation vertical slot, in described lifting
It is provided with electric rotating machine in block, the main shaft of described electric rotating machine is provided with column spinner, described column spinner declines in described elevator
When, stretched in described mixing drum and described column spinner and stirring mast stagger setting.
8. treatment fractures Chinese medicine composition it is characterised in that being provided with sealing at the opening of described cavity according to claim 4
Pad, described rotary shaft is wrapped in described sealing gasket.
9. treatment fracture Chinese medicine composition stirs palpus it is characterised in that described column spinner is provided with according to claim 4,
The roof of described stirring cylinder is provided with charging aperture and feeding detection mouth.
10. application in treatment fracture Chinese medicine for the treatment fracture Chinese medicine composition as claimed in claim 1.
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| CN201610898081.0A CN106344804A (en) | 2016-10-14 | 2016-10-14 | Traditional Chinese medicine composition for treating bone fracture, and preparation method thereof |
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| CN201610898081.0A CN106344804A (en) | 2016-10-14 | 2016-10-14 | Traditional Chinese medicine composition for treating bone fracture, and preparation method thereof |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110237888A (en) * | 2019-05-13 | 2019-09-17 | 杭州谈笑电子商务有限公司 | A kind of alcohol extraction procedure |
| CN110567761A (en) * | 2019-10-08 | 2019-12-13 | 全椒先奇医药科技有限公司 | Assay sample collection device for hospital |
| CN111939221A (en) * | 2020-08-26 | 2020-11-17 | 兴安界首骨伤医院有限公司 | Jianbu pills for late fracture and preparation method thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101073603A (en) * | 2006-05-18 | 2007-11-21 | 浙江南洋药业有限公司 | Huahong mixed suspended granule and its production |
| CN104740504A (en) * | 2013-12-25 | 2015-07-01 | 储海燕 | Traditional Chinese medicine decoction for treating femoral head necrosis |
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2016
- 2016-10-14 CN CN201610898081.0A patent/CN106344804A/en not_active Withdrawn
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101073603A (en) * | 2006-05-18 | 2007-11-21 | 浙江南洋药业有限公司 | Huahong mixed suspended granule and its production |
| CN104740504A (en) * | 2013-12-25 | 2015-07-01 | 储海燕 | Traditional Chinese medicine decoction for treating femoral head necrosis |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110237888A (en) * | 2019-05-13 | 2019-09-17 | 杭州谈笑电子商务有限公司 | A kind of alcohol extraction procedure |
| CN110567761A (en) * | 2019-10-08 | 2019-12-13 | 全椒先奇医药科技有限公司 | Assay sample collection device for hospital |
| CN111939221A (en) * | 2020-08-26 | 2020-11-17 | 兴安界首骨伤医院有限公司 | Jianbu pills for late fracture and preparation method thereof |
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