CN108968068A - A kind of Halth-care composition and preparation method thereof for alleviating diabetes complications - Google Patents

A kind of Halth-care composition and preparation method thereof for alleviating diabetes complications Download PDF

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Publication number
CN108968068A
CN108968068A CN201810900459.5A CN201810900459A CN108968068A CN 108968068 A CN108968068 A CN 108968068A CN 201810900459 A CN201810900459 A CN 201810900459A CN 108968068 A CN108968068 A CN 108968068A
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powder
mixed
halth
care composition
diabetes complications
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魏鹏
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    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/105Plant extracts, their artificial duplicates or their derivatives
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23PSHAPING OR WORKING OF FOODSTUFFS, NOT FULLY COVERED BY A SINGLE OTHER SUBCLASS
    • A23P10/00Shaping or working of foodstuffs characterised by the products
    • A23P10/30Encapsulation of particles, e.g. foodstuff additives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/42Cucurbitaceae (Cucumber family)
    • A61K36/428Trichosanthes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/481Astragalus (milkvetch)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/63Oleaceae (Olive family), e.g. jasmine, lilac or ash tree
    • A61K36/638Ligustrum, e.g. Chinese privet
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/65Paeoniaceae (Peony family), e.g. Chinese peony
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/80Scrophulariaceae (Figwort family)
    • A61K36/804Rehmannia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00Food compositions, function of food ingredients or processes for food or foodstuffs

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Botany (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Mycology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medical Informatics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Emergency Medicine (AREA)
  • Nutrition Science (AREA)
  • Endocrinology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

A kind of Halth-care composition and preparation method thereof for alleviating diabetes complications, the present invention relates to health product technology fields;It is made of following weight item: radix rehmanniae recen 280-310g, Radix Astragali 280-310g, fruit of glossy privet 280-310g, cortex moutan 280-310g, radices trichosanthis 280-310g.Its dose that can reduce drug, while the injection volume and frequency injection of insulin can also be reduced, effectively control blood glucose, practicability are stronger.

Description

A kind of Halth-care composition and preparation method thereof for alleviating diabetes complications
Technical field
The present invention relates to health product technology fields, and in particular to it is a kind of alleviate diabetes complications Halth-care composition and Preparation method.
Background technique
Diabetes are one group of metabolic diseases characterized by hyperglycemia.Hyperglycemia be then due to defect of insulin secretion or Its biological effect is impaired, or both have concurrently and cause.Long-standing hyperglycemia when diabetes, cause various tissues, especially eye, Kidney, heart, blood vessel, the chronic lesion of nerve, dysfunction, i.e. diabetic complication.
Drug or insulin injection are all made of for the glycemic control of diabetic at present, however, controlling blood at present The drug of sugar is Western medicine, and taking Western medicine for a long time will increase body burden, and insulin injection can bring pain to patient, due to pancreas islet Plain injection needle needs to refrigerate, therefore causes its inconvenient to carry, it would be highly desirable to improve.
Summary of the invention
In view of the defects and deficiencies of the prior art, the present invention intends to provide a kind of structure is simple, design rationally, make With the convenient Halth-care composition and preparation method thereof for alleviating diabetes complications, the dose of drug can be reduced, together When can also reduce the injection volume and frequency injection of insulin, effectively control blood glucose, practicability are stronger.
To achieve the above object, the Halth-care composition of the present invention for alleviating diabetes complications, it by weighing as follows It measures into and is grouped as: radix rehmanniae recen 280-310g, Radix Astragali 280-310g, fruit of glossy privet 280-310g, cortex moutan 280-310g, radices trichosanthis 280-310g。
Further, the Halth-care composition of the alleviation diabetes complications, it is made of following weight item: raw Glutinous rehmannia 295-310g, Radix Astragali 295-310g, fruit of glossy privet 295-310g, cortex moutan 295-310g, radices trichosanthis 295-310g.
Further, the Halth-care composition of the alleviation diabetes complications, it is made of following weight item: raw Glutinous rehmannia 300g, Radix Astragali 300g, fruit of glossy privet 300g, cortex moutan 300g, radices trichosanthis 300g.
The preparation method of the Halth-care composition of the present invention for alleviating diabetes complications, operating procedure are as follows:
1, choose the radix rehmanniae recen of 295-310g, the Radix Astragali of 295-310g, the fruit of glossy privet of 295-310g, 295-310g cortex moutan and Raw material is respectively adopted pulverizer mill and carries out pulverization process by the radices trichosanthis of 295-310g;
2, smashed powder is subjected to sieving processing, obtains the different powder of partial size;
3, it will be stirred in the raw material powder investment mixing plant in same particle size range, until powder is stirred, obtain different grains The mixed-powder of diameter;
4, the mixed-powder that will be mixed by the powder sieved, is fitted into packaging bag according to specification with powdered;
5, the mixed-powder not being mixed by the powder sieved is put into capsule assembly machine, after being assembled into capsule according to specification, Again by capsule tinning.
Further, the powder specifics in the packaging bag in the step 4 are 5g/ bags.
Further, powder specifics are 5g/ in capsule in the step 5.
Further, the powder in the step 2 passes through the sieving processing of 300 mesh and 800 mesh respectively, obtains three kinds respectively The powder of different-grain diameter.
Further, it will be mixed into mixed-powder by the powder of 800 meshes in the step 4, according to specification with powder Last shape is fitted into packaging bag.
Further, mixed powder will be mixed into not by 800 meshes but by the powder of 300 meshes in the step 5 End, while thinking to add water in mixed-powder and stir evenly, the weight ratio of water and mixed-powder is 1:10, mixed by what is stirred evenly It closes in object investment pellet processing machine, is processed into pill, the specification of the pill is 6g/.
Further, by the mixed-powder not being mixed by the powder of 300 meshes investment capsule dress in the step 5 With in machine, after being assembled into capsule according to specification, then by capsule tinning.
After above-mentioned technique, the invention has the following beneficial effects: a kind of guarantor for alleviating diabetes complications of the present invention Strong product composition and preparation method thereof, can reduce the dose of drug, at the same can also reduce insulin injection volume and Frequency injection, effectively control blood glucose, practicability are stronger.
Detailed description of the invention
In order to more clearly explain the embodiment of the invention or the technical proposal in the existing technology, to embodiment or will show below There is attached drawing needed in technical description to be briefly described, it should be apparent that, the accompanying drawings in the following description is only this Some embodiments of invention for those of ordinary skill in the art without creative efforts, can be with It obtains other drawings based on these drawings.
Fig. 1 is the Contrast on effect chart of the present embodiment.
Specific embodiment
The present invention will be further described below with reference to the drawings.
Referring to as shown in Figure 1, present embodiment the technical solution adopted is that: alleviation diabetes of the present invention disease The Halth-care composition of disease is sent out, it is made of following weight item: radix rehmanniae recen 300g, Radix Astragali 300g, fruit of glossy privet 300g, cortex moutan 300g, radices trichosanthis 300g.
Alleviate the preparation method of the Halth-care composition of diabetes complications, operation step described in present embodiment It is rapid as follows:
1, radix rehmanniae recen 300g, Radix Astragali 300g, fruit of glossy privet 300g, cortex moutan 300g, radices trichosanthis 300g are chosen, raw material is respectively adopted Pulverizer mill carries out pulverization process;
2, the sieving that smashed powder passes through 300 mesh and 800 mesh respectively is handled, obtains the powder of three kinds of different-grain diameters respectively, That is powder of the partial size less than 800mm, powder and partial size that partial size is between 300-800mm are greater than the powder of 300mm;
3, it will be stirred in the raw material powder investment mixing plant in same particle size range, until powder is stirred, obtain three kinds not With the mixed-powder of partial size;
4, it will be mixed into mixed-powder by the powder of 800 meshes, is fitted into packaging bag according to specification with powdered, powder specifics It is 5g/ bags;
5, it will be mixed into mixed-powder not by 800 meshes but by the powder of 300 meshes, while thinks to add water in mixed-powder And stir evenly, the weight ratio of water and mixed-powder is 1:10, and the mixture stirred evenly is put into pellet processing machine, processes patent medicine Ball, the specification of the pill are 6g/;
6, the mixed-powder not being mixed by the powder of 300 meshes is put into capsule assembly machine, assembles plastic according to specification After capsule, then by capsule tinning, powder specifics are 5g/ in capsule.
After above-mentioned technique, present embodiment has the beneficial effect that a kind of alleviation described in present embodiment Halth-care composition of diabetes complications and preparation method thereof can reduce the dose of drug, while can also reduce The injection volume and frequency injection of insulin, effectively control blood glucose, practicability are stronger.
Embodiment one:
On June 30, -2018 years on the 1st January in 2018, the diabetic Mr. Wang that sick age is 5 years, women, take at 55 one full year of life It states the powder being processed into specific embodiment six months, twice a day, each one bag sooner or later, is taken, taken with plain boiled water Daily early morning fasting blood-glucose is measured in journey, while the number of insulin injection every month is counted.
Embodiment two:
On June 30, -2018 years on the 1st January in 2018, Lee diabetic that sick age is 2 years, women, 50 one full year of life take above-mentioned The pill being processed into specific embodiment six months twice a day each one sooner or later, is taken with plain boiled water, is taking process In daily early morning fasting blood-glucose is measured, while the number of insulin injection every month is counted.
Embodiment three:
On June 30, -2018 years on the 1st January in 2018, the diabetic Sun that sick age is 10 years, women, take at 65 one full year of life The capsule being processed into above-mentioned specific embodiment six months twice a day each one sooner or later, is sent with plain boiled water, was being taken Daily early morning fasting blood-glucose is measured in journey, while the number of insulin injection every month is counted.
By experimental data comparison it is found that using the Halth-care composition being processed into present embodiment, energy Enough play the role of control glucostasis, and reduces insulin injection amount.
The above is only used to illustrate the technical scheme of the present invention and not to limit it, and those of ordinary skill in the art are to this hair The other modifications or equivalent replacement that bright technical solution is made, as long as it does not depart from the spirit and scope of the technical scheme of the present invention, It is intended to be within the scope of the claims of the invention.

Claims (10)

1. a kind of Halth-care composition for alleviating diabetes complications, it is characterised in that: it is made of following weight item: Radix Rehmanniae Yellow 280-310g, Radix Astragali 280-310g, fruit of glossy privet 280-310g, cortex moutan 280-310g, radices trichosanthis 280-310g.
2. a kind of Halth-care composition for alleviating diabetes complications according to claim 1, it is characterised in that: it is by such as Lower weight item composition: radix rehmanniae recen 295-310g, Radix Astragali 295-310g, fruit of glossy privet 295-310g, cortex moutan 295-310g, smallpox Powder 295-310g.
3. a kind of Halth-care composition for alleviating diabetes complications according to claim 1, it is characterised in that: it is by such as Lower weight item composition: radix rehmanniae recen 300g, Radix Astragali 300g, fruit of glossy privet 300g, cortex moutan 300g, radices trichosanthis 300g.
4. a kind of preparation method for the Halth-care composition for alleviating diabetes complications, it is characterised in that: its operating procedure is as follows:
(1), the cortex moutan of the radix rehmanniae recen of 295-310g, the Radix Astragali of 295-310g, the fruit of glossy privet of 295-310g, 295-310g are chosen With the radices trichosanthis of 295-310g, pulverizer mill is respectively adopted in raw material and carries out pulverization process;
(2), smashed powder is subjected to sieving processing, obtains the different powder of partial size;
(3), it will stir in the raw material powder investment mixing plant in same particle size range, until powder is stirred, obtain different The mixed-powder of partial size;
(4), the mixed-powder that will be mixed by the powder sieved, is fitted into packaging bag according to specification with powdered;
(5), the mixed-powder not being mixed by the powder sieved is put into capsule assembly machine, is assembled into capsule according to specification Afterwards, then by capsule tinning.
5. a kind of preparation method of Halth-care composition for alleviating diabetes complications according to claim 1, feature Be: the powder specifics in packaging bag in the step (4) are 5g/ bags.
6. a kind of preparation method of Halth-care composition for alleviating diabetes complications according to claim 1, feature Be: powder specifics are 5g/ in capsule in the step (5).
7. a kind of preparation method of Halth-care composition for alleviating diabetes complications according to claim 1, feature Be: the powder in the step (2) passes through the sieving processing of 300 mesh and 800 mesh respectively, obtains three kinds of different-grain diameters respectively Powder.
8. a kind of preparation method of Halth-care composition for alleviating diabetes complications according to claim 7, feature It is: mixed-powder will be mixed by the powder of 800 meshes in the step (4), is wrapped according to specification with powdered loading In pack.
9. a kind of preparation method of Halth-care composition for alleviating diabetes complications according to claim 7, feature It is: mixed-powder will be mixed into not by 800 meshes but by the powder of 300 meshes in the step (5), while wanting to mix It closes and adds water in powder and stir evenly, the weight ratio of water and mixed-powder is 1:10, and the mixture stirred evenly is put into and is made In ball machine, it is processed into pill, the specification of the pill is 6g/.
10. a kind of preparation method of Halth-care composition for alleviating diabetes complications according to claim 7, feature It is: the mixed-powder not being mixed by the powder of 300 meshes is put into capsule assembly machine in the step (5), is pressed After being assembled into capsule according to specification, then by capsule tinning.
CN201810900459.5A 2018-08-09 2018-08-09 A kind of Halth-care composition and preparation method thereof for alleviating diabetes complications Pending CN108968068A (en)

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Citations (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1221620A (en) * 1998-12-01 1999-07-07 王显民 Compound medicine for treating diabets mellitus
CN1418667A (en) * 2002-11-26 2003-05-21 贵州家诚药业有限责任公司 Chinese patent drug for treating diabets mellitus
CN1679814A (en) * 2005-01-21 2005-10-12 邹巧根 Infusion liquid of glossy privet fruit and astragalus root for strengthening body resistance and its making method
CN1899361A (en) * 2006-07-14 2007-01-24 贵州信邦制药股份有限公司 Zhenqi medicinal composition and its preparation
CN1977884A (en) * 2005-12-08 2007-06-13 天津中新药业集团股份有限公司乐仁堂制药厂 Medicinal composition for treating diabetes and its preparing method
CN101239153A (en) * 2007-02-09 2008-08-13 佟丽波 Medicament for treating diabetes
CN101559081A (en) * 2009-05-06 2009-10-21 李文新 Application of river clam extract in preparation of medicament for curing and preventing diabetes mellitus
CN102579674A (en) * 2012-03-15 2012-07-18 郭世伟 Chinese herba astragalus powder for curing diabetes mellitus
CN103006789A (en) * 2012-12-21 2013-04-03 贵州信邦制药股份有限公司 Preparation method of Glossy privet fruit and radix astragali sustained release preparations and product
CN103405654A (en) * 2013-04-19 2013-11-27 陕西步长高新制药有限公司 Traditional Chinese medicine pharmaceutical composition for treating diabetes and preparation method thereof

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1221620A (en) * 1998-12-01 1999-07-07 王显民 Compound medicine for treating diabets mellitus
CN1418667A (en) * 2002-11-26 2003-05-21 贵州家诚药业有限责任公司 Chinese patent drug for treating diabets mellitus
CN1679814A (en) * 2005-01-21 2005-10-12 邹巧根 Infusion liquid of glossy privet fruit and astragalus root for strengthening body resistance and its making method
CN1977884A (en) * 2005-12-08 2007-06-13 天津中新药业集团股份有限公司乐仁堂制药厂 Medicinal composition for treating diabetes and its preparing method
CN1899361A (en) * 2006-07-14 2007-01-24 贵州信邦制药股份有限公司 Zhenqi medicinal composition and its preparation
CN101239153A (en) * 2007-02-09 2008-08-13 佟丽波 Medicament for treating diabetes
CN101559081A (en) * 2009-05-06 2009-10-21 李文新 Application of river clam extract in preparation of medicament for curing and preventing diabetes mellitus
CN102579674A (en) * 2012-03-15 2012-07-18 郭世伟 Chinese herba astragalus powder for curing diabetes mellitus
CN103006789A (en) * 2012-12-21 2013-04-03 贵州信邦制药股份有限公司 Preparation method of Glossy privet fruit and radix astragali sustained release preparations and product
CN103405654A (en) * 2013-04-19 2013-11-27 陕西步长高新制药有限公司 Traditional Chinese medicine pharmaceutical composition for treating diabetes and preparation method thereof

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* Cited by examiner, † Cited by third party
Title
刘春梅: ""中医治疗糖尿病用药规律及效果的分析研究"" *
刘春梅;: "中医治疗糖尿病用药规律及效果的分析研究", 糖尿病新世界 *

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Application publication date: 20181211