CN108967787A - A kind of India's ivy gourd leaf beverage and preparation method thereof with effect of lowering blood sugar - Google Patents
A kind of India's ivy gourd leaf beverage and preparation method thereof with effect of lowering blood sugar Download PDFInfo
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- CN108967787A CN108967787A CN201810896077.XA CN201810896077A CN108967787A CN 108967787 A CN108967787 A CN 108967787A CN 201810896077 A CN201810896077 A CN 201810896077A CN 108967787 A CN108967787 A CN 108967787A
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- india
- ivy gourd
- gourd leaf
- ivy
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- 240000006560 Coccinia grandis Species 0.000 title claims abstract description 100
- 235000006165 Coccinia grandis Nutrition 0.000 title claims abstract description 100
- 235000013361 beverage Nutrition 0.000 title claims abstract description 39
- 238000002360 preparation method Methods 0.000 title claims abstract description 15
- 239000008280 blood Substances 0.000 title claims description 37
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- 230000000694 effects Effects 0.000 title claims description 31
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 24
- 239000000284 extract Substances 0.000 claims abstract description 21
- UEDUENGHJMELGK-HYDKPPNVSA-N Stevioside Chemical compound O([C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1O[C@]12C(=C)C[C@@]3(C1)CC[C@@H]1[C@@](C)(CCC[C@]1([C@@H]3CC2)C)C(=O)O[C@H]1[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O1)O)[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O UEDUENGHJMELGK-HYDKPPNVSA-N 0.000 claims abstract description 14
- 229940013618 stevioside Drugs 0.000 claims abstract description 14
- OHHNJQXIOPOJSC-UHFFFAOYSA-N stevioside Natural products CC1(CCCC2(C)C3(C)CCC4(CC3(CCC12C)CC4=C)OC5OC(CO)C(O)C(O)C5OC6OC(CO)C(O)C(O)C6O)C(=O)OC7OC(CO)C(O)C(O)C7O OHHNJQXIOPOJSC-UHFFFAOYSA-N 0.000 claims abstract description 14
- 235000019202 steviosides Nutrition 0.000 claims abstract description 14
- CHHHXKFHOYLYRE-UHFFFAOYSA-M 2,4-Hexadienoic acid, potassium salt (1:1), (2E,4E)- Chemical compound [K+].CC=CC=CC([O-])=O CHHHXKFHOYLYRE-UHFFFAOYSA-M 0.000 claims abstract description 11
- 229940069338 potassium sorbate Drugs 0.000 claims abstract description 11
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- 239000004302 potassium sorbate Substances 0.000 claims abstract description 11
- 238000001914 filtration Methods 0.000 claims abstract description 10
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- 238000005516 engineering process Methods 0.000 claims abstract description 8
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- 239000002994 raw material Substances 0.000 abstract description 4
- QFVOYBUQQBFCRH-UHFFFAOYSA-N Steviol Natural products C1CC2(C3)CC(=C)C3(O)CCC2C2(C)C1C(C)(C(O)=O)CCC2 QFVOYBUQQBFCRH-UHFFFAOYSA-N 0.000 abstract description 2
- 210000004534 cecum Anatomy 0.000 abstract description 2
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- 244000005700 microbiome Species 0.000 abstract description 2
- QFVOYBUQQBFCRH-VQSWZGCSSA-N steviol Chemical compound C([C@@]1(O)C(=C)C[C@@]2(C1)CC1)C[C@H]2[C@@]2(C)[C@H]1[C@](C)(C(O)=O)CCC2 QFVOYBUQQBFCRH-VQSWZGCSSA-N 0.000 abstract description 2
- 229940032084 steviol Drugs 0.000 abstract description 2
- 238000012360 testing method Methods 0.000 description 20
- 206010012601 diabetes mellitus Diseases 0.000 description 15
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 8
- 241000699666 Mus <mouse, genus> Species 0.000 description 8
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- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 description 2
- 244000269722 Thea sinensis Species 0.000 description 2
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- ZNNLBTZKUZBEKO-UHFFFAOYSA-N glyburide Chemical compound COC1=CC=C(Cl)C=C1C(=O)NCCC1=CC=C(S(=O)(=O)NC(=O)NC2CCCCC2)C=C1 ZNNLBTZKUZBEKO-UHFFFAOYSA-N 0.000 description 2
- 238000002347 injection Methods 0.000 description 2
- 239000007924 injection Substances 0.000 description 2
- 229940125396 insulin Drugs 0.000 description 2
- 239000002504 physiological saline solution Substances 0.000 description 2
- 239000000243 solution Substances 0.000 description 2
- 239000005720 sucrose Substances 0.000 description 2
- 235000013616 tea Nutrition 0.000 description 2
- 235000013311 vegetables Nutrition 0.000 description 2
- FPIPGXGPPPQFEQ-UHFFFAOYSA-N 13-cis retinol Natural products OCC=C(C)C=CC=C(C)C=CC1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-UHFFFAOYSA-N 0.000 description 1
- 208000024172 Cardiovascular disease Diseases 0.000 description 1
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- 241000533770 Cayaponia Species 0.000 description 1
- AUNGANRZJHBGPY-UHFFFAOYSA-N D-Lyxoflavin Natural products OCC(O)C(O)C(O)CN1C=2C=C(C)C(C)=CC=2N=C2C1=NC(=O)NC2=O AUNGANRZJHBGPY-UHFFFAOYSA-N 0.000 description 1
- 239000009920 Diasulin Substances 0.000 description 1
- 208000000913 Kidney Calculi Diseases 0.000 description 1
- 244000302512 Momordica charantia Species 0.000 description 1
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- AUNGANRZJHBGPY-SCRDCRAPSA-N Riboflavin Chemical compound OC[C@@H](O)[C@@H](O)[C@@H](O)CN1C=2C=C(C)C(C)=CC=2N=C2C1=NC(=O)NC2=O AUNGANRZJHBGPY-SCRDCRAPSA-N 0.000 description 1
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- 235000006092 Stevia rebaudiana Nutrition 0.000 description 1
- ZSJLQEPLLKMAKR-UHFFFAOYSA-N Streptozotocin Natural products O=NN(C)C(=O)NC1C(O)OC(CO)C(O)C1O ZSJLQEPLLKMAKR-UHFFFAOYSA-N 0.000 description 1
- FPIPGXGPPPQFEQ-BOOMUCAASA-N Vitamin A Natural products OC/C=C(/C)\C=C\C=C(\C)/C=C/C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-BOOMUCAASA-N 0.000 description 1
- 229930003451 Vitamin B1 Natural products 0.000 description 1
- 229930003471 Vitamin B2 Natural products 0.000 description 1
- 244000273928 Zingiber officinale Species 0.000 description 1
- 235000006886 Zingiber officinale Nutrition 0.000 description 1
- 230000003044 adaptive effect Effects 0.000 description 1
- FPIPGXGPPPQFEQ-OVSJKPMPSA-N all-trans-retinol Chemical compound OC\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-OVSJKPMPSA-N 0.000 description 1
- 238000004458 analytical method Methods 0.000 description 1
- 239000002012 ayurvedic medicine Substances 0.000 description 1
- 210000000227 basophil cell of anterior lobe of hypophysis Anatomy 0.000 description 1
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- 230000009977 dual effect Effects 0.000 description 1
- 235000013399 edible fruits Nutrition 0.000 description 1
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- 235000008397 ginger Nutrition 0.000 description 1
- 241000411851 herbal medicine Species 0.000 description 1
- 235000020344 instant tea Nutrition 0.000 description 1
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- 230000001737 promoting effect Effects 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 230000008929 regeneration Effects 0.000 description 1
- 238000011069 regeneration method Methods 0.000 description 1
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- 229960002477 riboflavin Drugs 0.000 description 1
- 230000028327 secretion Effects 0.000 description 1
- 239000001509 sodium citrate Substances 0.000 description 1
- NLJMYIDDQXHKNR-UHFFFAOYSA-K sodium citrate Chemical compound O.O.[Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O NLJMYIDDQXHKNR-UHFFFAOYSA-K 0.000 description 1
- 210000002784 stomach Anatomy 0.000 description 1
- ZSJLQEPLLKMAKR-GKHCUFPYSA-N streptozocin Chemical compound O=NN(C)C(=O)N[C@H]1[C@@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O ZSJLQEPLLKMAKR-GKHCUFPYSA-N 0.000 description 1
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- 229960003495 thiamine Drugs 0.000 description 1
- DPJRMOMPQZCRJU-UHFFFAOYSA-M thiamine hydrochloride Chemical compound Cl.[Cl-].CC1=C(CCO)SC=[N+]1CC1=CN=C(C)N=C1N DPJRMOMPQZCRJU-UHFFFAOYSA-M 0.000 description 1
- 238000002604 ultrasonography Methods 0.000 description 1
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- 210000003462 vein Anatomy 0.000 description 1
- 235000019155 vitamin A Nutrition 0.000 description 1
- 239000011719 vitamin A Substances 0.000 description 1
- 235000010374 vitamin B1 Nutrition 0.000 description 1
- 239000011691 vitamin B1 Substances 0.000 description 1
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Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
- A23L2/38—Other non-alcoholic beverages
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
- A23L2/52—Adding ingredients
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
- A23L2/52—Adding ingredients
- A23L2/60—Sweeteners
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
- A23L2/70—Clarifying or fining of non-alcoholic beverages; Removing unwanted matter
- A23L2/72—Clarifying or fining of non-alcoholic beverages; Removing unwanted matter by filtration
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/105—Plant extracts, their artificial duplicates or their derivatives
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/125—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives containing carbohydrate syrups; containing sugars; containing sugar alcohols; containing starch hydrolysates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/42—Cucurbitaceae (Cucumber family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Abstract
The invention discloses and a kind of India's ivy gourd leaf beverage and preparation method thereof, which mainly uses India's ivy gourd leaf water extract and water to be prepared.When preparation, moisture is dried in India's ivy gourd leaf cleaning of selection, then tiles, finishes 1-2 hours, be cooled to room temperature under certain temperature；India's ivy gourd leaf is beaten together with pure water, filtering, then stevioside, potassium sorbate are added to by a certain percentage in India's ivy gourd leaf extract, it adds pure water and dilutes 1~10 times, ultra high temperature short time sterilization technology sterilizes after filtering again, filling and sealing under aseptic condition.India's ivy gourd leaf beverage of the present invention, raw material are pure natural, pollution-free, and smell faint scent, mouthfeel are pure and fresh, heat is low, and stevioside is not digested in upper digestive tract, is partly absorbed after alimentary canal lower section is mainly decomposed into steviol by cecum microorganisms.
Description
[technical field]
The present invention relates to a kind of India's ivy gourd leaf beverage with effect of lowering blood sugar, and preparation method thereof, belong to plant function
It can property technical field of beverage.
[background technique]
Diabetes are a kind of because of hypoinsulinism, cause to divide in fat, protein, disturbance of carbohydrate metabolism etc.
Secrete the chronic metabolic disease of imbalance.2017, the investigation result of International Diabetes Federation was shown, global diabetes adult patient
Reach 4.25 hundred million, wherein diabetes mellitus in China patient 1.144 hundred million, occupies the whole world first.Currently, what diabetes were eradicated completely not yet
Method, mainly based on Western medicine Chinese patent drug, keep on a diet supplemented by treatment means control diabetes, to reduce complication
Occur, but Western medicine is expensive, Chinese patent drug pharmacological property is complicated, and mouthfeel is bad, this brings many bad to diabetic
Experience problem.
India's ivy gourd (Coccinia grandis) belongs to the perennial liana of Curcurbitaceae, is the famous medicinal vegetable in South Asia
Dish, whole plant is all edible, and fruit is sweet and delicious, and it is edible that young stem and leaf can do vegetables.Indian red is used in Ayurvedic medicine
Herbal medicine of the melon leaf as treatment diabetes confirms that India's ivy gourd young stem and leaf has treatment diabetes function by the human experiment of centuries
Effect.And there is scholar to study discovery India's ivy gourd blade in 24 kinds of plants such as Moringa, balsam pear, American Ginseng, ginger, hypoglycemic activity
It ranked first.External much researchs have confirmed that India's ivy gourd blade can be rated as " glucokinin engine ", hypoglycemic main machine
It is made as secretion or the biosynthetic insulin of insulin being improved, to reach by promoting the beta cell regeneration of pancreas in living body
Reduce blood glucose effect.In addition, ivy gourd blade also has inoxidizability, prevention cardiovascular disease, brings down a fever, treats kidney stone, protection
Nervous system and other effects, it is without side-effects, highly-safe.Directly edible ivy gourd blade, mouthfeel is more rough, and directly juicing also has jerky
Sense, and its hypoglycemic effective component cannot be fully utilized.
Overseas market Shang Youji money India ivy gourd Related product at present is mainly used for diabetes, urinary tract infections and diet and mends
Agent is filled, it is expensive such as Mersina capsule, Diasulin capsule, ivy gourd alec.And hypoglycemic beverage has mulberry on domestic market
Leaf tea, A Erfa diabetic tea, with ridge board Jin Liwang beverage, guava instant tea, beverage products type is less, and raw material is more single
One, and innovate inadequate, it is most important that whether effect is significant and indefinite.In conclusion the drink of exploitation pure natural hypoglycemic
It is most important.
[summary of the invention]
An object of the present invention is to overcome prior art defect, provides a kind of utilization rate height, the without side-effects and mouth of safety
The India's ivy gourd leaf beverage with effect of lowering blood sugar felt.
It is a further object of the present invention to provide a kind of preparation methods of above-mentioned India's ivy gourd leaf beverage.
The present invention to achieve the above object, using following technical scheme:
A kind of India's ivy gourd leaf beverage with effect of lowering blood sugar, it is characterised in that mainly use India's ivy gourd leaf extract
It is prepared with water.India's ivy gourd leaf extract is preferably water extract in the present invention.
It further include stevioside and potassium sorbate in the present invention.
In India's ivy gourd beverage of the present invention, India's ivy gourd leaf extract accounts for the 70-80% of gross weight, stevioside 0.1-0.5%,
Potassium sorbate 0.01-0.02%, remaining is water.
India's ivy gourd leaf in the present invention preferably uses light green India's ivy gourd blade.India's ivy gourd blade rich in vitamin A,
It is vitamin B1 and B2, full of nutrition, and yield is high, can be used for volume production processing India's ivy gourd natural hypoglycemic beverage.
Stevioside is to extract to obtain from catananche's STEVIA REBAUDIANA, is that a kind of sugariness is high, heat is low, high temperature resistant, peace
Atoxic, the natural sweetener for having the effect of extending the shelf life, sugariness is 200-350 times of sucrose, and heat only has the 1/ of sucrose
300.The noresidue in human body is conducive to adjust blood glucose, has auxiliary treatment functio to diabetes patient.
A kind of preparation method of above-mentioned India's ivy gourd leaf beverage with effect of lowering blood sugar, comprising the following steps:
A, moisture is dried into India's ivy gourd leaf cleaning of selection；
B, the India's ivy gourd blade for drying moisture is tiled, is finished 1-2 hours at a temperature of 55 DEG C -60 DEG C, is cooled to often
Temperature；
C, India's ivy gourd blade chopping of water-removing is placed in container, pure water mashing is added, filtering obtains India's ivy gourd
Leaf extract；
D, stevioside, potassium sorbate are added to by a certain percentage in India's ivy gourd leaf extract, season, adds pure
Water dilutes 1~10 times, filters again, obtains India's ivy gourd leaf clear liquid；
F, it is sterilized using 125~150 DEG C of temperature, the ultra high temperature short time sterilization technology of 4~20s of time, is filled under aseptic condition
Dress sealing.
In preparation method of the present invention, in step c, the pure water that is added and India ivy gourd leaf are same when India's ivy gourd blade is beaten
Etc. weight, preferably mashing 3-5min, filter the sieve of preferred 100-120 mesh.
In preparation method step d of the present invention, each raw material mixing revolving speed is 1500r/min, 15-20min is stirred, then in function
Ultrasonic homogeneous 30-60min under conditions of rate 250-400W, at 50-85 DEG C of temperature.
In preparation method of the present invention, the time of ultra high temperature short time sterilization is preferably 5-10s.
Compared with prior art, the present invention has the following advantages:
India's ivy gourd leaf beverage of the present invention, raw material are pure natural, pollution-free, and smell faint scent, mouthfeel are pure and fresh, heat is low,
And stevioside is not digested in upper digestive tract, after alimentary canal lower section is mainly decomposed into steviol by cecum microorganisms
It is partly absorbed.Processing technology of the present invention is simple, cost is relatively low, and this law fully remain it is hypoglycemic in India's ivy gourd blade
Effective component.Small white mouse experiment display India's ivy gourd leaf beverage has significant effect of lowering blood sugar, and small range is after human experiment,
Not only there is significant blood sugar decreasing effect and without any side effects.India's ivy gourd beverage can meet hyperglycemia population and pursue high-quality life
Living and mouthfeel dual requirements.
[specific embodiment]
Further more detailed description is done to the present invention below in conjunction with specific embodiment.
A kind of India's ivy gourd leaf beverage with effect of lowering blood sugar, is prepared by the following method:
A, it chooses fresh India's ivy gourd leaf cleaning and dries moisture；
B, the India's ivy gourd blade for drying moisture is tiled, is finished 1-2 hours at a temperature of 55 DEG C -60 DEG C, is cooled to often
Temperature；
C, the India's ivy gourd blade chopping for weighing quantitative water-removing is placed in container, is added 0.8-1.2 times of leaf of India's ivy gourd and is weighed
The pure water of amount is beaten 3-5min, and 100-120 mesh net filtration obtains India's ivy gourd leaf extract；
D, stevioside, potassium sorbate are proportionally added into India's ivy gourd leaf extract, add pure water dilution 1~
10 times mix through 1500r/min high-speed stirred 15-20min, then through 60-65 DEG C, 250-400W power ultrasound homogeneous 30-60min
Uniformly, it filters again, obtains India's ivy gourd leaf clear liquid；
F, it is sterilized using 125~150 DEG C of temperature, the ultra high temperature short time sterilization technology of 4~20s of time, is filled under aseptic condition
Dress sealing.
Embodiment 1:
A kind of India's ivy gourd leaf beverage with effect of lowering blood sugar, is prepared by the following method:
A, it chooses light green India's ivy gourd leaf cleaning and dries moisture；
B, the India's ivy gourd blade for drying moisture is tiled, finish 1h at a temperature of 55 DEG C, is cooled to room temperature；
C, the India's ivy gourd blade chopping for weighing 1000g water-removing is placed in container, and 1000g pure water is added and is beaten 3min,
100 mesh net filtrations obtain India's ivy gourd leaf extract；
D, 1g stevioside, 0.1g potassium sorbate are added in India's ivy gourd leaf extract, add pure water dilution 4
Times, the high-speed stirred 15min through 1500r/min, the ultrasonic homogeneous 30min under 65 DEG C of temperature, power 300W, 100 mesh screens
Filtering is filtered again, obtains India's ivy gourd leaf clear liquid；
F, it is sterilized using 130 DEG C of temperature, the ultra high temperature short time sterilization technology of time 8s, filling and sealing is under aseptic condition
It can.
Embodiment 2:
A kind of India's ivy gourd leaf beverage with effect of lowering blood sugar, is prepared by the following method:
A, moisture is dried into fresh disease-free India's ivy gourd leaf cleaning；
B, the India's ivy gourd blade for drying moisture is laid in baking pan, is finished at a temperature of 58 DEG C in baking room
1.5h is cooled to room temperature；
C, the India's ivy gourd blade chopping for weighing 1000g water-removing is placed in container, and 800g pure water is added and is beaten 4min,
110 mesh net filtrations obtain India's ivy gourd leaf extract；
D, 1.5g stevioside, 0.15g potassium sorbate are added in India's ivy gourd leaf extract, add pure water dilution
8 times, through revolving speed 1500r/min high-speed stirred 18min, ultrasonic homogeneous is carried out under conditions of temperature 60 C, power 350W
45min, 110 mesh screens filter again, obtain India's ivy gourd leaf clear liquid；
F, it is sterilized using 135 DEG C of temperature, the ultra high temperature short time sterilization technology of time 8s, filling and sealing is under aseptic condition
It can.
Embodiment 3:
A kind of India's ivy gourd leaf beverage with effect of lowering blood sugar, is prepared by the following method:
A, moisture is dried into fresh disease-free India's ivy gourd leaf cleaning；
B, the India's ivy gourd blade for drying moisture is laid in baking pan, water-removing 2 is small at a temperature of 55 DEG C in baking room
When, it is cooled to room temperature；
C, the India's ivy gourd blade chopping for weighing 1000g water-removing is placed in container, and 1200g pure water juicing 5min is added,
120 mesh net filtrations obtain India's ivy gourd leaf extract；
D, 2g stevioside, 0.2g potassium sorbate are added in India's ivy gourd leaf extract, add pure water dilution 10
Times, through revolving speed 1500r/min high-speed stirred 18min, ultrasonic homogeneous is carried out under conditions of 65 DEG C of temperature, power 350W
60min, 120 mesh screens filter again, obtain India's ivy gourd leaf clear liquid；
F, it is sterilized using 125 DEG C of temperature, the ultra high temperature short time sterilization technology of time 15s, filling and sealing is under aseptic condition
It can.
India's ivy gourd leaf beverage of the present invention effect evaluation hypoglycemic to diabetic mice is as follows.
1. mouse test:
By after mouse adaptive feeding 5d before experiment, mouse is divided into blank group and model group, to blank pair after fasting 12h
According to a group physiological saline for injection same dose, the sodium citrate that model group mouse peritoneal injects 0.lmg/gbw streptozotocin is slow
Solution is rushed, restores normal diet after injection, fasting 5h after 3d measures blood glucose, chooses blood glucose and is higher than 11.1mmo1/L mouse 24
It is divided into 3 groups (hyperglycemia model group, positive groups, test group).Blank control group and hyperglycemia model group stomach-filling physiological saline, test
Group is stomach-filling embodiment 1-3 (given low 10mLkg-1), positive controls are stomach-filling glibenclamide solution (5mgkg-1),
Daily stomach-filling 2 times, continuous gavage 3 weeks.Fasting blood sugar is measured, the results are shown in Table 1.
Table 1: the influence that India's ivy gourd leaf beverage changes mouse blood sugar
Note: different letters indicate there is extremely significant difference (p < 0.0l) in table, and the data of test group are
The average value of embodiment 1,2,3.
As a result it is indicated with average ± standard deviation, carries out variance analysis with SPSS statistical software.As shown in Table 1, hyperglycemia
The fasting blood sugar of model group is 5.83 times of blank control group, has significant difference (p < 0.01), shows mouse hyperglycemia
Model foundation success.The positive group blood glucose value compared with hyperglycemia model group, reduce 19.05%, have significant difference (p <
0.05).The blood glucose value of test group reduces 32.37% compared with hyperglycemia model group, has significant difference (p < 0.05).Examination
Group is tested compared with positive group, and there was no significant difference, illustrates that the curative effect of India's ivy gourd leaf beverage is consistent with the effect of glibenclamide.
2. human trial
50 ages are chosen in 40 years old or more diabetic as study subject, male: female=1:1 is randomly divided into three
Group (control group, test group 1, test group 2), every group of 10 people, test group 2 is divided into embodiment 1,2,3 again.Test the previous day, own
People eats identical dinner, and keeps 10h on an empty stomach.During test, all subjects eat identical substance, in addition, test group 1
India's ivy gourd leaf of same amount, test group 2 are drunk the beverage 500mL of embodiment 1-3 daily respectively, are tried in daily edible beverage
It tests before starting, the blood glucose level that extracting vein blood measures subject after test 2h.The results are shown in Table 2.
The influence of 2 India's ivy gourd leaf of table and its beverage to blood sugar in diabetic patients level
Note: the data of test group 2 are the average value of embodiment 1,2,3.
As shown in Table 2, compared with the control group, test group test 2h after blood glucose level be remarkably decreased (p < 0.05), respectively under
Drop 15.73%, 24.42%.Compared with test group 1, test 2h blood glucose level is remarkably decreased (p < 0.05) test group 2, is declined
10.31%, this illustrates that the blood sugar decreasing effect of India's ivy gourd leaf beverage is more preferable than the effect of fresh leaf.
Claims (10)
1. a kind of India's ivy gourd leaf beverage with effect of lowering blood sugar, it is characterised in that mainly using India's ivy gourd leaf extract and
Water is prepared.
2. a kind of India's ivy gourd leaf beverage with effect of lowering blood sugar according to claim 1, it is characterised in that further include
Stevioside and potassium sorbate.
3. a kind of India's ivy gourd leaf beverage with effect of lowering blood sugar according to claim 2, it is characterised in that described
India's ivy gourd leaf extract accounts for the 70-80% of gross weight, and stevioside accounts for the 0.1-0.5% of gross weight, and potassium sorbate accounts for 0.01-
0.02%, remaining is water.
4. a kind of India's ivy gourd leaf beverage with effect of lowering blood sugar according to claim 1, it is characterised in that described
India's ivy gourd leaf selects light green India's ivy gourd blade.
5. a kind of India's ivy gourd leaf beverage with effect of lowering blood sugar according to claim 1, it is characterised in that described
India's ivy gourd leaf extract is water extract.
6. a kind of preparation method of India's ivy gourd leaf beverage of any of claims 1-5 with effect of lowering blood sugar,
Characterized by the following steps:
A, moisture is dried into India's ivy gourd leaf cleaning of selection；
B, the India's ivy gourd blade for drying moisture is tiled, finishes 1-2 hours, is cooled to room temperature at a temperature of 55 DEG C -60 DEG C；
C, India's ivy gourd blade chopping of water-removing is placed in container, pure water mashing is added, filtering obtains India's ivy gourd leaf and mentions
Take object；
D, stevioside, potassium sorbate are proportionally added into India's ivy gourd leaf extract, add pure water and dilutes 1~10 times
It mixes, filters again, obtain India's ivy gourd leaf clear liquid；
F, it is sterilized using 125~150 DEG C of temperature, the ultra high temperature short time sterilization technology of 4~20s of time, filling envelope under aseptic condition
Mouthful.
7. the preparation method of India's ivy gourd leaf beverage according to claim 6 with effect of lowering blood sugar, it is characterised in that
In the step c, the pure water weight that India's ivy gourd blade is added when being beaten is 0.8-1.2 times of India's ivy gourd leaf weight,
120-120 mesh net filtration.
8. the preparation method of India's ivy gourd leaf beverage according to claim 6 with effect of lowering blood sugar, it is characterised in that
Being uniformly mixed in the step d includes two steps of high-speed stirred and ultrasonic homogeneous.
9. according to benefit require 8 described in effect of lowering blood sugar India's ivy gourd leaf beverage preparation method, it is characterised in that institute
The revolving speed for the high-speed stirred stated is 1500r/min, mixing time 15-20min.
10. according to benefit require 8 described in effect of lowering blood sugar India's ivy gourd leaf beverage preparation method, it is characterised in that institute
The ultrasonic processing condition stated is power 250-400W, homogenizing time 30-60min.
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| CN110477321A (en) * | 2019-08-23 | 2019-11-22 | 中山市海枣椰农业科技有限公司 | A kind of naturally toning and jam flavor ivy gourd foodstuff base material and preparation method thereof |
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