CN108937864A - Mucous membrane of mouth induces fluorescence detection diagnostic equipment - Google Patents
Mucous membrane of mouth induces fluorescence detection diagnostic equipment Download PDFInfo
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- CN108937864A CN108937864A CN201810577697.7A CN201810577697A CN108937864A CN 108937864 A CN108937864 A CN 108937864A CN 201810577697 A CN201810577697 A CN 201810577697A CN 108937864 A CN108937864 A CN 108937864A
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- mucous membrane
- diagnostic equipment
- fluorescence detection
- cylinder
- light source
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
- A61B5/0071—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence by measuring fluorescence emission
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- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
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- Biophysics (AREA)
- Pathology (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Physics & Mathematics (AREA)
- Molecular Biology (AREA)
- Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
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- Veterinary Medicine (AREA)
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Abstract
The present invention discloses a kind of mucous membrane of mouth induction fluorescence detection diagnostic equipment, cover board including cylinder, photographic device and photosensitizer for inducing fluorescence, cylinder open at one end, the other end is equipped with through-hole, cylinder inboard wall is equipped with excitation light source and lighting source, and photographic device includes display screen.The present invention can induce histofluorescence, according to the imaging of fluorescence and its change of imaging property, realize early diagnosis, antidiastole and the curative effect follow-up of the potential malignant disease canceration of oral mucosal disease, especially mucous membrane of mouth.
Description
Technical field
The present invention relates to medical instrument fields more particularly to a kind of mucous membrane of mouth to induce fluorescence detection diagnostic equipment.
Background technique
Fluorescence diagnosis has become the common auxiliary of one kind of the potential malignant disease canceration of oral mucosal disease, especially mucous membrane of mouth
Diagnostic method, existing fluorescence oral cavity detection device are passed through by the intracorporal fluorescent lamp tissue of cylinder, then using photographic device
Cylinder is imaged and is shown to tissue.The device is primarily present following deficiency:
1, what is obtained is the autofluorescence of tissue, is shone fainter, the difference of pathological tissues and normal tissue is unobvious, shadow
Ring diagnosis.
2, autofluorescence is easy the interference by disease damage part cuticle thickness and inflammatory conditions, false positive, false negative rate
It is high.
3, the white light and fluorescent image that can not obtain pathological tissues simultaneously are not easy to track to compare to retouch meter with disease damage range.
Summary of the invention
It is lured the present invention is intended to provide a kind of mucous membrane of mouth induces fluorescence detection diagnostic equipment in conjunction with the local use of photosensitizer
Pathological tissues and normal tissue can be better discriminated between, be conducive to mucous membrane of mouth according to the variation of fluorescence Spectra by issuing histofluorescence
Disease especially early diagnoses the potential malignant disease canceration of mucous membrane of mouth, antidiastole and curative effect follow-up.
In order to achieve the above objectives, realization that the present invention adopts the following technical solutions:
Mucous membrane of mouth disclosed by the invention induces fluorescence detection diagnostic equipment, including cylinder, photographic device and for inducing hair
The photosensitizer of light, the cylinder open at one end, the cover board of the other end are equipped with through-hole, and cylinder is equipped with excitation light source and illumination light
Source, the photographic device include display screen.
In use, photosensitizer is first coated in oral cavity mucous membrane tissue surface, then the fluorescence irradiation, the excitation that pass through specific wavelength
Tissue generates fluorescence, since absorptivity of the photosensitizer in pathological tissues is higher than normal tissue, so as to glimmering by observing
The intensity, distinguishes pathological tissues of the light pathological tissues different with normal tissue, antidiastole.
Preferably, the wavelength of the excitation light source is 280~500nm.
Further, the photographic device further includes processing unit and communication interface, and the communication interface, display screen connect
Connect processing unit.
Preferably, the excitation light source, lighting source are annular lamp tube, and are supported by transparent support, described
Bright supporting element connector drum inner wall.
Further preferred, the excitation light source, lighting source are located at the same radial section of cylinder.
Further, the lighting source, excitation light source are equipped with key switch, and the key switch is located at outside cylinder
Wall.
Preferably, the lighting source is white light.
Preferably, one end of the photographic device and cylinder is detachably connected.
Beneficial effects of the present invention are as follows:
1, the present invention is equipped with the photosensitizer for induced luminescence, the suction due to pathological tissues and normal tissue to photosensitizer
Yield is different, so that pathological tissues are stimulated, the fluorescence of generation is become apparent from, and is conducive to diagnosis, antidiastole and state of an illness follow-up.
2, the present invention is equipped with lighting source, convenient to carry out observation and Image Acquisition to the region that detected under white light.
3, the present invention is equipped with the excitation light source that wavelength is 280~500nm, it is convenient under excitation light, to needing detection zone
Fluorescence carry out observation and Image Acquisition.Meanwhile excitation light source and lighting source can switch over, and the same position of observation is facilitated to exist
Disease damage feature under fluorescence and white light, and disease damage range is carried out to retouch meter.
4, the present invention is equipped with communication interface, other intelligent terminals or intelligence instrument is facilitated to access.
Detailed description of the invention
Fig. 1 is partition schematic diagram of the invention.
Fig. 2 is the axial sectional view of shell portion.
Fig. 3 is the circuit diagram of photographic device.
Fig. 4 is the circuit diagram of shell portion.
In figure: 1- cylinder, 2- photographic device, 11- cover board, 12- through-hole, the first key switch of 13-, the second key of 14- are opened
Pass, 15- excitation light source, 16- lighting source, power supply 17,21- display screen, 22- communication interface.
Specific embodiment
In order to make the objectives, technical solutions, and advantages of the present invention clearer, below in conjunction with attached drawing, to the present invention into
Row is further described.
As shown in Figure 1 and Figure 2, mucous membrane of mouth disclosed by the invention induces fluorescence detection diagnostic equipment, including cylinder 1, camera shooting dress
Set 2 and for induced luminescence photosensitizer, 1 open at one end of cylinder, the cover board 11 of the other end is equipped with through-hole 12, cylinder 1 it is interior
Wall is equipped with excitation light source 15 and lighting source 16, and the wavelength of excitation light source is 280~380nm, excitation light source 15, lighting source
16 be annular lamp tube, and is supported by transparent support 17,17 connector drum inner wall of transparent support, and excitation light source 15 shines
Mingguang City source 16 is located at the same radial section of cylinder.Excitation light source 15 is equipped with the first key switch 13, and lighting source 16 is equipped with the
Two key switches 14, the first key switch 13, the second key switch 14 are mounted on the outer wall of cylinder 1.
Photographic device 2 can also be detachably connected independently of cylinder 1 with one end of cylinder 1.
As shown in figure 3, photographic device 2 includes display screen 21, processing unit and communication interface 22；Communication interface, display screen
It is all connected with processing unit；Certainly, photographic device further includes camera, and camera connects processing unit.
As shown in figure 4, the first series arm and the second key switch of the first key switch 13, excitation light source 15 composition
14, it is connected to power supply 17 after the second series arm that lighting source 16 forms is in parallel, dry cell or chargeable can be used in power supply 17
Battery when using rechargeable battery, can be equipped with corresponding charge power supply, and filling for charging interface and charge power supply is arranged on cylinder 1
The matching of electric wire cable.
Certainly, the present invention can also have other various embodiments, without deviating from the spirit and substance of the present invention, ripe
Various corresponding changes and modifications, but these corresponding changes and modifications can be made according to the present invention by knowing those skilled in the art
All it should fall within the scope of protection of the appended claims of the present invention.
Claims (8)
1. mucous membrane of mouth induces fluorescence detection diagnostic equipment, it is characterised in that: including cylinder, photographic device and for induced luminescence
Photosensitizer, the cylinder open at one end, the cover board of the other end are equipped with through-hole, and cylinder inboard wall is equipped with excitation light source and illumination light
Source, the photographic device include display screen.
2. mucous membrane of mouth according to claim 1 induces fluorescence detection diagnostic equipment, it is characterised in that: the excitation light source
Wavelength is 280~500nm.
3. mucous membrane of mouth according to claim 1 induces fluorescence detection diagnostic equipment, it is characterised in that: the photographic device is also
Including processing unit and communication interface, the communication interface, display screen are all connected with processing unit.
4. mucous membrane of mouth according to claim 1 induces fluorescence detection diagnostic equipment, it is characterised in that: the excitation light source,
Lighting source is annular lamp tube, and is supported by transparent support, the transparent support connector drum inner wall.
5. mucous membrane of mouth according to claim 4 induces fluorescence detection diagnostic equipment, it is characterised in that: the excitation light source,
Lighting source is located at the same radial section of cylinder.
6. mucous membrane of mouth according to claim 1 induces fluorescence detection diagnostic equipment, it is characterised in that: the lighting source,
Excitation light source is equipped with key switch, and the key switch is located at cylinder body outer wall.
7. mucous membrane of mouth according to claim 1 induces fluorescence detection diagnostic equipment, it is characterised in that: the lighting source is
White light.
8. mucous membrane of mouth according to claim 1 induces fluorescence detection diagnostic equipment, it is characterised in that: the photographic device with
One end of cylinder is detachably connected.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810577697.7A CN108937864A (en) | 2018-06-05 | 2018-06-05 | Mucous membrane of mouth induces fluorescence detection diagnostic equipment |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810577697.7A CN108937864A (en) | 2018-06-05 | 2018-06-05 | Mucous membrane of mouth induces fluorescence detection diagnostic equipment |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN108937864A true CN108937864A (en) | 2018-12-07 |
Family
ID=64493859
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201810577697.7A Pending CN108937864A (en) | 2018-06-05 | 2018-06-05 | Mucous membrane of mouth induces fluorescence detection diagnostic equipment |
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| Country | Link |
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Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2550816A1 (en) * | 2005-06-29 | 2006-12-29 | Johnson & Johnson Consumer Companies, Inc. | Handheld device for determining skin age, proliferation status and photodamage level |
| WO2007078447A2 (en) * | 2006-01-01 | 2007-07-12 | Venous Light, Llc | Micro vein enhancer |
| CN103445877A (en) * | 2012-06-01 | 2013-12-18 | 索尼公司 | Dental apparatus, medical apparatus and calculation method |
| CN105181422A (en) * | 2015-09-29 | 2015-12-23 | 武汉大学 | Kit for benign lesion identification and malignant lesion detection of oral mucosa and detection method thereof |
| CN106187793A (en) * | 2016-01-26 | 2016-12-07 | 赵鸣 | 5 aminolevulinic acids and the salt compound of derivant thereof and application |
| CN206080474U (en) * | 2016-06-29 | 2017-04-12 | 郑洪� | Oral cavity inspection device, handheld part and endoscope |
-
2018
- 2018-06-05 CN CN201810577697.7A patent/CN108937864A/en active Pending
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2550816A1 (en) * | 2005-06-29 | 2006-12-29 | Johnson & Johnson Consumer Companies, Inc. | Handheld device for determining skin age, proliferation status and photodamage level |
| WO2007078447A2 (en) * | 2006-01-01 | 2007-07-12 | Venous Light, Llc | Micro vein enhancer |
| CN103445877A (en) * | 2012-06-01 | 2013-12-18 | 索尼公司 | Dental apparatus, medical apparatus and calculation method |
| CN105181422A (en) * | 2015-09-29 | 2015-12-23 | 武汉大学 | Kit for benign lesion identification and malignant lesion detection of oral mucosa and detection method thereof |
| CN106187793A (en) * | 2016-01-26 | 2016-12-07 | 赵鸣 | 5 aminolevulinic acids and the salt compound of derivant thereof and application |
| CN206080474U (en) * | 2016-06-29 | 2017-04-12 | 郑洪� | Oral cavity inspection device, handheld part and endoscope |
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| RJ01 | Rejection of invention patent application after publication | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20181207 |