CN108883167A - 用于预防和治疗外阴阴道念珠菌病的方法和药剂盒 - Google Patents
用于预防和治疗外阴阴道念珠菌病的方法和药剂盒 Download PDFInfo
- Publication number
- CN108883167A CN108883167A CN201780020274.9A CN201780020274A CN108883167A CN 108883167 A CN108883167 A CN 108883167A CN 201780020274 A CN201780020274 A CN 201780020274A CN 108883167 A CN108883167 A CN 108883167A
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- China
- Prior art keywords
- als3
- thr
- polypeptide
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0002—Fungal antigens, e.g. Trichophyton, Aspergillus, Candida
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4196—1,2,4-Triazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
- A61K33/08—Oxides; Hydroxides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/168—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/02—Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55505—Inorganic adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Mycology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Botany (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Inorganic Chemistry (AREA)
- Oncology (AREA)
- Reproductive Health (AREA)
- Gynecology & Obstetrics (AREA)
- Communicable Diseases (AREA)
- Endocrinology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662305714P | 2016-03-09 | 2016-03-09 | |
| US62/305,714 | 2016-03-09 | ||
| PCT/US2017/021094 WO2017155949A1 (en) | 2016-03-09 | 2017-03-07 | Methods and kits for use in preventing and treating vulvovaginal candidiasis |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN108883167A true CN108883167A (zh) | 2018-11-23 |
Family
ID=59790870
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201780020274.9A Pending CN108883167A (zh) | 2016-03-09 | 2017-03-07 | 用于预防和治疗外阴阴道念珠菌病的方法和药剂盒 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US10857216B2 (https=) |
| EP (1) | EP3426287A4 (https=) |
| JP (1) | JP2019507759A (https=) |
| CN (1) | CN108883167A (https=) |
| WO (1) | WO2017155949A1 (https=) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20070077256A1 (en) | 1999-11-19 | 2007-04-05 | Los Angeles Biomedical Research Institute | Pharmaceutical compositions and methods to vaccinate against disseminated candidiasis and other infectious agents |
| GEP201706766B (en) | 2011-07-22 | 2017-10-25 | Los Angeles Biomedical Res Center | Methods and compositions for vaccinating against staphylococcus aureus |
| US10130691B2 (en) | 2013-03-15 | 2018-11-20 | Los Angeles Biomedical Research Institute At Harbor-Ucla Medical Center | Compositions and methods for treating fungal and bacterial pathogens |
| EP3426287A4 (en) | 2016-03-09 | 2020-03-11 | Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center | Methods and kits for use in preventing and treating vulvovaginal candidiasis |
| JP7439371B2 (ja) * | 2018-04-10 | 2024-02-28 | ロサンゼルス バイオメディカル リサーチ インスティテュート アット ハーバー- ユーシーエルエー メディカル センター | Candida auris感染症の治療方法 |
| EP3552620A1 (en) * | 2018-04-11 | 2019-10-16 | Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center | Methods of treatment for candida auris infections |
| WO2022140646A1 (en) * | 2020-12-26 | 2022-06-30 | Mycovia Pharmaceuticals, Inc | Dosing regimen for oteseconazole |
| JP2022191716A (ja) | 2021-06-16 | 2022-12-28 | ローム・アンド・ハース・エレクトロニック・マテリアルズ・コリア・リミテッド | Uv硬化性シリコーン組成物及びその硬化物 |
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| US5961970A (en) | 1993-10-29 | 1999-10-05 | Pharmos Corporation | Submicron emulsions as vaccine adjuvants |
| WO1995031998A1 (en) | 1994-05-23 | 1995-11-30 | The Research & Development Institute, Inc. | Candida albicans adhesin as a vaccine |
| US5668263A (en) | 1994-12-16 | 1997-09-16 | Smithkline Beecham Corporation | Conserved yeast nucleic acid sequences |
| US6500438B2 (en) | 1995-06-07 | 2002-12-31 | Pfizer Incorporated | In ovo vaccination against coccidiosis |
| DE69734601T2 (de) | 1996-05-16 | 2006-08-03 | The Texas A & M University System, College Station | Zusammensetzung von kollagenbindungsprotein und verfahren zu deren verwendungen |
| WO1998009990A1 (en) * | 1996-09-04 | 1998-03-12 | Takara Shuzo Co., Ltd. | Fungal antigens and process for producing the same |
| US6747137B1 (en) | 1998-02-13 | 2004-06-08 | Genome Therapeutics Corporation | Nucleic acid sequences relating to Candida albicans for diagnostics and therapeutics |
| US6248329B1 (en) | 1998-06-01 | 2001-06-19 | Ramaswamy Chandrashekar | Parasitic helminth cuticlin nucleic acid molecules and uses thereof |
| US6703025B1 (en) | 1998-08-31 | 2004-03-09 | Inhibitex, Inc. | Multicomponent vaccines |
| US20060083750A1 (en) | 1999-11-19 | 2006-04-20 | Los Angeles Biomedical Research Institute At Harbor-Ucla Medical Center | Pharmaceutical compositions and methods to vaccinate against disseminated candidiasis |
| US20070077256A1 (en) | 1999-11-19 | 2007-04-05 | Los Angeles Biomedical Research Institute | Pharmaceutical compositions and methods to vaccinate against disseminated candidiasis and other infectious agents |
| US8541008B2 (en) | 1999-11-19 | 2013-09-24 | Los Angeles Biomedical Research Institute At Harbor-Ucla Medical Center | Pharmaceutical compositions and methods to vaccinate against candidiasis |
| US7067138B1 (en) | 1999-11-19 | 2006-06-27 | Los Angeles Biomedical Research Institute At Harbor-Ucla Medical Center | Pharmaceutical compositions and methods to vaccinate against disseminated candidiasis |
| JP3717104B2 (ja) | 2000-05-30 | 2005-11-16 | シャープ株式会社 | 回路内蔵受光素子 |
| FR2814741B1 (fr) | 2000-09-29 | 2004-02-27 | Atofina | Procede de stabilisation de monomeres acryliques |
| US6579820B2 (en) | 2001-03-21 | 2003-06-17 | The Boc Group, Inc. | Reactor modifications for NOx reduction from a fluid catalytic cracking regeneration vessel |
| EP2319301B1 (en) | 2001-11-30 | 2017-09-06 | Amgen Fremont Inc. | Transgenic animals bearing human Ig lambda light chain genes |
| DE10216281B4 (de) | 2002-04-12 | 2007-04-12 | Noé, Reinhold, Prof. Dr.-Ing. | Anordnung und Verfahren für eine Dispersionsdetektion |
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| US20050287146A1 (en) | 2003-12-19 | 2005-12-29 | Joseph Patti | Method of inhibiting Candida-related infections using donor selected or donor stimulated immunoglobulin compositions |
| GB0420466D0 (en) | 2004-09-14 | 2004-10-20 | Cassone Antonio | Anti-glucan antibodies |
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| CA2489194A1 (en) | 2004-12-03 | 2006-06-03 | Guilhem Janbon | Polypeptides involved in candida biofilm formation and uses thereof |
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| GEP201706766B (en) * | 2011-07-22 | 2017-10-25 | Los Angeles Biomedical Res Center | Methods and compositions for vaccinating against staphylococcus aureus |
| BR112014005773A2 (pt) | 2011-09-14 | 2019-09-24 | Los Angeles Biomedical Research Institute At Harbor-Ucla Medical Center | composições derivadas de hyr1 e métodos of tratamento usando as mesmas |
| US20160030533A1 (en) | 2013-03-15 | 2016-02-04 | Los Angeles Biomedical Research Institute At Harbor-Ucla Medical Center | Compositions and methods of treating fungal and bacterial pathogens |
| WO2014144024A1 (en) | 2013-03-15 | 2014-09-18 | Los Angeles Biomedical Research Institute At Harbor-Ucla Medical Center | Hyr1 compositions and methods for treating fungal and bacterial pathogens |
| US10130691B2 (en) * | 2013-03-15 | 2018-11-20 | Los Angeles Biomedical Research Institute At Harbor-Ucla Medical Center | Compositions and methods for treating fungal and bacterial pathogens |
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| EP3426287A4 (en) | 2016-03-09 | 2020-03-11 | Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center | Methods and kits for use in preventing and treating vulvovaginal candidiasis |
-
2017
- 2017-03-07 EP EP17763871.5A patent/EP3426287A4/en not_active Withdrawn
- 2017-03-07 CN CN201780020274.9A patent/CN108883167A/zh active Pending
- 2017-03-07 WO PCT/US2017/021094 patent/WO2017155949A1/en not_active Ceased
- 2017-03-07 US US16/081,062 patent/US10857216B2/en active Active
- 2017-03-07 JP JP2018544888A patent/JP2019507759A/ja active Pending
Non-Patent Citations (2)
| Title |
|---|
| ASHRAF S. IBRAHIM等: "NDV-3 Protects Mice From Vulvovaginal Candidiasis Through T-and B-Cell Immune Response", 《VACCINE》 * |
| CLINT S.SCHMIDT等: "NDV-3, a recombinant alum-adjuvanted vaccine for Candida and Staphylococcus aureus,is safe and immunogenic in healthy adults", 《VACCINE》 * |
Also Published As
| Publication number | Publication date |
|---|---|
| EP3426287A1 (en) | 2019-01-16 |
| EP3426287A4 (en) | 2020-03-11 |
| US10857216B2 (en) | 2020-12-08 |
| US20190076512A1 (en) | 2019-03-14 |
| WO2017155949A1 (en) | 2017-09-14 |
| JP2019507759A (ja) | 2019-03-22 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20181123 |
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| WD01 | Invention patent application deemed withdrawn after publication |