CN108883155A - 蛋白化合物及其用途 - Google Patents

蛋白化合物及其用途 Download PDF

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Publication number
CN108883155A
CN108883155A CN201780021694.9A CN201780021694A CN108883155A CN 108883155 A CN108883155 A CN 108883155A CN 201780021694 A CN201780021694 A CN 201780021694A CN 108883155 A CN108883155 A CN 108883155A
Authority
CN
China
Prior art keywords
amino acid
protein molecule
pkc
cells
acid residues
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201780021694.9A
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English (en)
Chinese (zh)
Inventor
苏达·拉奥
彼得·米尔本
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Canberra
Original Assignee
University of Canberra
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from AU2016900314A external-priority patent/AU2016900314A0/en
Application filed by University of Canberra filed Critical University of Canberra
Priority to CN202211550292.7A priority Critical patent/CN116082457A/zh
Publication of CN108883155A publication Critical patent/CN108883155A/zh
Pending legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y207/00—Transferases transferring phosphorus-containing groups (2.7)
    • C12Y207/11—Protein-serine/threonine kinases (2.7.11)
    • C12Y207/11013—Protein kinase C (2.7.11.13)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CN201780021694.9A 2016-02-01 2017-02-01 蛋白化合物及其用途 Pending CN108883155A (zh)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202211550292.7A CN116082457A (zh) 2016-02-01 2017-02-01 蛋白化合物及其用途

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
AU2016900314 2016-02-01
AU2016900314A AU2016900314A0 (en) 2016-02-01 Proteinaceous compounds and uses therefor
PCT/AU2017/050083 WO2017132728A1 (en) 2016-02-01 2017-02-01 Proteinaceous compounds and uses therefor

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CN202211550292.7A Division CN116082457A (zh) 2016-02-01 2017-02-01 蛋白化合物及其用途

Publications (1)

Publication Number Publication Date
CN108883155A true CN108883155A (zh) 2018-11-23

Family

ID=59499146

Family Applications (2)

Application Number Title Priority Date Filing Date
CN201780021694.9A Pending CN108883155A (zh) 2016-02-01 2017-02-01 蛋白化合物及其用途
CN202211550292.7A Pending CN116082457A (zh) 2016-02-01 2017-02-01 蛋白化合物及其用途

Family Applications After (1)

Application Number Title Priority Date Filing Date
CN202211550292.7A Pending CN116082457A (zh) 2016-02-01 2017-02-01 蛋白化合物及其用途

Country Status (8)

Country Link
US (1) US10487115B2 (https=)
EP (1) EP3411061A4 (https=)
JP (2) JP7341451B2 (https=)
CN (2) CN108883155A (https=)
AU (1) AU2017214761B2 (https=)
CA (1) CA3011870A1 (https=)
SG (1) SG11201806122YA (https=)
WO (1) WO2017132728A1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2019090390A1 (en) * 2017-11-08 2019-05-16 University Of Canberra Immunogenic compositions and uses therefor

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103328499A (zh) * 2010-11-01 2013-09-25 悉尼科技大学 免疫调节剂及其用途
CN103547296A (zh) * 2011-03-11 2014-01-29 非营利性组织佛兰芒综合大学生物技术研究所 用于抑制和检测蛋白质的分子和方法
WO2015039187A1 (en) * 2013-09-18 2015-03-26 University Of Canberra Stem cell modulation ii

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US4873192A (en) 1987-02-17 1989-10-10 The United States Of America As Represented By The Department Of Health And Human Services Process for site specific mutagenesis without phenotypic selection
ATE285477T1 (de) 1995-06-07 2005-01-15 Inex Pharmaceutical Corp Herstellung von lipid-nukleinsäure partikeln duch ein hydrophobische lipid-nukleinsäuree komplexe zwischenprodukt und zur verwendung in der gentransfer
GB9624482D0 (en) 1995-12-18 1997-01-15 Zeneca Phaema S A Chemical compounds
BR9707495A (pt) 1996-02-13 1999-07-27 Zeneca Ltd Derivado de quinazolina processo para a preparação do mesmo composição farmacêutica e processo para a produç o de um efeito antiangiogênico e/ou de redução de permeabilidade vascular em um animal de sangue quente
US6291455B1 (en) 1996-03-05 2001-09-18 Zeneca Limited 4-anilinoquinazoline derivatives
GB9718972D0 (en) 1996-09-25 1997-11-12 Zeneca Ltd Chemical compounds
GB9714249D0 (en) 1997-07-08 1997-09-10 Angiogene Pharm Ltd Vascular damaging agents
EP1002091B1 (en) 1997-07-09 2012-02-29 Coridon Pty Limited Nucleic acid sequence and method for selectively expressing a protein in a target cell or tissue
AUPP807899A0 (en) 1999-01-08 1999-02-04 University Of Queensland, The Codon utilization
WO2000036083A2 (en) * 1998-12-17 2000-06-22 La Jolla Institute For Allergy And Immunology Pkc-interacting cousin of trx (picot) polypeptides, polynucleotides, and methods of making and using them
GB9900334D0 (en) 1999-01-07 1999-02-24 Angiogene Pharm Ltd Tricylic vascular damaging agents
GB9900752D0 (en) 1999-01-15 1999-03-03 Angiogene Pharm Ltd Benzimidazole vascular damaging agents
NZ522074A (en) 2000-05-31 2004-06-25 Astrazeneca Ab Indole derivatives with vascular damaging activity
CN1255392C (zh) 2000-07-07 2006-05-10 安吉奥金尼药品有限公司 作为血管生成抑制剂的秋水仙醇衍生物
IL153484A0 (en) 2000-07-07 2003-07-06 Angiogene Pharm Ltd Colchinol derivatives as angiogenesis inhibitors
CA2405728A1 (en) 2000-07-31 2002-02-07 Dabur Research Foundation Lipid-peptide conjugates for treatment of cancer
AU2003236720A1 (en) 2002-06-14 2003-12-31 Altana Pharma Ag Substituted diaminopyrimidines
WO2004076654A1 (en) * 2003-02-28 2004-09-10 Novartis Ag Three-dimensional structure of the catalytic domain of protein c theta, methods and use thereof
CA2604243C (en) 2004-04-14 2015-11-24 Avirid, Inc. Compositions with modified nucleases targeted to viral nucleic acids and methods of use for prevention and treatment of viral diseases
KR100859972B1 (ko) 2006-02-20 2008-09-25 이화여자대학교 산학협력단 막투과 단백질 도메인 펩타이드
AU2013323101C1 (en) 2012-09-27 2021-08-19 University Of British Columbia Peptide directed protein knockdown
CA2958704A1 (en) 2014-08-25 2016-03-03 University Of Canberra Compositions for modulating cancer stem cells and uses therefor

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103328499A (zh) * 2010-11-01 2013-09-25 悉尼科技大学 免疫调节剂及其用途
CN103547296A (zh) * 2011-03-11 2014-01-29 非营利性组织佛兰芒综合大学生物技术研究所 用于抑制和检测蛋白质的分子和方法
WO2015039187A1 (en) * 2013-09-18 2015-03-26 University Of Canberra Stem cell modulation ii

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
ELISSA L. SUTCLIFFE1 ET AL.: "Chromatinized protein kinase C-": can it escape the clutches of NF-kB?", 《FRONTIERS IN IMMUNOLOGY》 *

Also Published As

Publication number Publication date
JP2019506167A (ja) 2019-03-07
SG11201806122YA (en) 2018-08-30
JP2022023949A (ja) 2022-02-08
WO2017132728A1 (en) 2017-08-10
AU2017214761B2 (en) 2024-02-01
JP7341451B2 (ja) 2023-09-11
AU2017214761A1 (en) 2018-08-02
EP3411061A4 (en) 2019-07-10
CN116082457A (zh) 2023-05-09
EP3411061A1 (en) 2018-12-12
US10487115B2 (en) 2019-11-26
US20190040103A1 (en) 2019-02-07
CA3011870A1 (en) 2017-08-10

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Application publication date: 20181123

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