SG11201806122YA - Proteinaceous compounds and uses therefor - Google Patents

Proteinaceous compounds and uses therefor

Info

Publication number
SG11201806122YA
SG11201806122YA SG11201806122YA SG11201806122YA SG11201806122YA SG 11201806122Y A SG11201806122Y A SG 11201806122YA SG 11201806122Y A SG11201806122Y A SG 11201806122YA SG 11201806122Y A SG11201806122Y A SG 11201806122YA SG 11201806122Y A SG11201806122Y A SG 11201806122YA
Authority
SG
Singapore
Prior art keywords
international
pct
pkc
english
february
Prior art date
Application number
SG11201806122YA
Inventor
Sudha Rao
Peter Milburn
Original Assignee
Univ Canberra
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from AU2016900314A external-priority patent/AU2016900314A0/en
Application filed by Univ Canberra filed Critical Univ Canberra
Publication of SG11201806122YA publication Critical patent/SG11201806122YA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/08Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/12Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y207/00Transferases transferring phosphorus-containing groups (2.7)
    • C12Y207/11Protein-serine/threonine kinases (2.7.11)
    • C12Y207/11013Protein kinase C (2.7.11.13)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Enzymes And Modification Thereof (AREA)

Abstract

INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization International Bureau (43) International Publication Date 10 August 2017 (10.08.2017) WIPO I PCT (10) International Publication Number WO 2017/132728 Al 11111111111110110111111111110101111101111111011101011110111011111111111111111 (51) International Patent Classification: A61K 38/17 (2006.01) A61P 35/00 (2006.01) A61K 38/43 (2006.01) (21) International Application Number: PCT/AU2017/050083 (22) International Filing Date: 1 February 2017 (01.02.2017) (25) Filing Language: English (26) Publication Language: English (30) Priority Data: 2016900314 1 February 2016 (01.02.2016) AU (71) Applicant: UNIVERSITY OF CANBERRA [AU/AU]; University Drive, Bruce, Australian Capital Territory 2617 (AU). (72) Inventors: RAO, Sudha; 102 Buxton Street, Deakin, Aus- tralian Capital Territory 2600 (AU). MILBURN, Peter; 8 Miller Street, O'Connor, Australian Capital Territory 2602 (AU). (74) Agent: DAVIES COLLISON CAVE PTY LTD; Level 10, 301 Coronation Drive, Milton, Queensland 4064 (AU). (81) Designated States (unless otherwise indicated, for every kind of national protection available): AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (84) Designated States (unless otherwise indicated, for every kind of regional protection available): ARIPO (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG). Published: — with international search report (Art. 21(3)) W O 20 17 / 13 27 28 Al (54) Title: PROTEINACEOUS COMPOUNDS AND USES THEREFOR (57) : Disclosed are proteinaceous molecules and their use in conditions associated with PKC-0 overexpression, such as cancer. More particularly, the present invention discloses proteinaceous molecules and their use in altering at least one of (i) forma - tion; (ii) proliferation; (iii) maintenance; (iv) epithelial to mesenchymal cell transition; or (v) mesenchymal to epithelial cell trans - ition of a PKC-0 overexpressing cell.
SG11201806122YA 2016-02-01 2017-02-01 Proteinaceous compounds and uses therefor SG11201806122YA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AU2016900314A AU2016900314A0 (en) 2016-02-01 Proteinaceous compounds and uses therefor
PCT/AU2017/050083 WO2017132728A1 (en) 2016-02-01 2017-02-01 Proteinaceous compounds and uses therefor

Publications (1)

Publication Number Publication Date
SG11201806122YA true SG11201806122YA (en) 2018-08-30

Family

ID=59499146

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201806122YA SG11201806122YA (en) 2016-02-01 2017-02-01 Proteinaceous compounds and uses therefor

Country Status (8)

Country Link
US (1) US10487115B2 (en)
EP (1) EP3411061A4 (en)
JP (2) JP7341451B2 (en)
CN (2) CN108883155A (en)
AU (1) AU2017214761B2 (en)
CA (1) CA3011870A1 (en)
SG (1) SG11201806122YA (en)
WO (1) WO2017132728A1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111587120A (en) * 2017-11-08 2020-08-25 艾比克斯治疗私人有限公司 Immunogenic compositions and uses thereof

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4873192A (en) 1987-02-17 1989-10-10 The United States Of America As Represented By The Department Of Health And Human Services Process for site specific mutagenesis without phenotypic selection
CA2222328C (en) 1995-06-07 2012-01-10 Inex Pharmaceuticals Corporation Lipid-nucleic acid particles prepared via a hydrophobic lipid-nucleic acid complex intermediate and use for gene transfer
GB9624482D0 (en) 1995-12-18 1997-01-15 Zeneca Phaema S A Chemical compounds
IL125686A (en) 1996-02-13 2002-11-10 Zeneca Ltd Quinazoline derivatives, processes for their preparation, pharmaceutical compositions containing them and their use in the manufacture of a medicament having an antiangiogenic and/or vascular permeability reducing effect
WO1997032856A1 (en) 1996-03-05 1997-09-12 Zeneca Limited 4-anilinoquinazoline derivatives
GB9718972D0 (en) 1996-09-25 1997-11-12 Zeneca Ltd Chemical compounds
GB9714249D0 (en) 1997-07-08 1997-09-10 Angiogene Pharm Ltd Vascular damaging agents
CA2296067C (en) 1997-07-09 2008-10-07 The University Of Queensland Nucleic acid sequence and method for selectively expressing a protein in a target cell or tissue
AUPP807899A0 (en) 1999-01-08 1999-02-04 University Of Queensland, The Codon utilization
WO2000036083A2 (en) 1998-12-17 2000-06-22 La Jolla Institute For Allergy And Immunology Pkc-interacting cousin of trx (picot) polypeptides, polynucleotides, and methods of making and using them
GB9900334D0 (en) 1999-01-07 1999-02-24 Angiogene Pharm Ltd Tricylic vascular damaging agents
GB9900752D0 (en) 1999-01-15 1999-03-03 Angiogene Pharm Ltd Benzimidazole vascular damaging agents
IL152682A0 (en) 2000-05-31 2003-06-24 Astrazeneca Ab Indole derivatives with vascular damaging activity
WO2002004434A1 (en) 2000-07-07 2002-01-17 Angiogene Pharmaceuticals Limited Colchinol derivatives as vascular damaging agents
RU2003103603A (en) 2000-07-07 2004-08-20 Энджиоджен Фармасьютикалз Лимитед (Gb) Derivatives of colchinol as inhibitors of angiogenesis
WO2002010193A1 (en) * 2000-07-31 2002-02-07 Dabur Research Foundation Lipid-peptide conjugates for treatment of cancer
AU2003236720A1 (en) 2002-06-14 2003-12-31 Altana Pharma Ag Substituted diaminopyrimidines
WO2004076654A1 (en) * 2003-02-28 2004-09-10 Novartis Ag Three-dimensional structure of the catalytic domain of protein c theta, methods and use thereof
WO2005115444A2 (en) 2004-04-14 2005-12-08 Avirid, Inc. Compositions with modified nucleases targeted to viral nucleic acids and methods of use for prevention and treatment of viral diseases
JP5295785B2 (en) 2006-02-20 2013-09-18 エファ・ユニバーシティ・インダストリー・コラボレイション・ファウンデイション Cell membrane permeable peptide
WO2012058715A1 (en) * 2010-11-01 2012-05-10 University Of Technology, Sydney Immune-modulating agents and uses therefor
ES2679995T3 (en) * 2011-03-11 2018-09-03 Vib Vzw Molecules and methods for protein inhibition and detection
CN112225819A (en) 2012-09-27 2021-01-15 不列颠哥伦比亚大学 Peptide-directed protein knockdown
ES2851724T3 (en) * 2013-09-18 2021-09-08 Epiaxis Therapeutics Pty Ltd Stem cell modulation
CA2958704A1 (en) 2014-08-25 2016-03-03 University Of Canberra Compositions for modulating cancer stem cells and uses therefor

Also Published As

Publication number Publication date
CN108883155A (en) 2018-11-23
JP7341451B2 (en) 2023-09-11
AU2017214761B2 (en) 2024-02-01
CA3011870A1 (en) 2017-08-10
EP3411061A4 (en) 2019-07-10
JP2019506167A (en) 2019-03-07
WO2017132728A1 (en) 2017-08-10
JP2022023949A (en) 2022-02-08
AU2017214761A1 (en) 2018-08-02
CN116082457A (en) 2023-05-09
US20190040103A1 (en) 2019-02-07
US10487115B2 (en) 2019-11-26
EP3411061A1 (en) 2018-12-12

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