CN108853173A - It is a kind of to treat skin disease external application acetum and preparation method - Google Patents
It is a kind of to treat skin disease external application acetum and preparation method Download PDFInfo
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Abstract
Skin disease external application acetum and preparation method are treated the invention particularly discloses a kind of, belongs to field of traditional Chinese medicine preparation.It is a kind of to treat skin disease external application acetum, it is the 31.25g containing Shrubalthea Bark in every 1000g product, cuts careless 31.25g, the vinegar of semen momordicae 31.25g and surplus is made；The present invention is a kind of to treat skin disease external application vinegar product, used time is applied to affected part, to kill based on various bacteriums and fungi, and it is antipruritic to take into account desinsection, to dermatitis, neurodermatitis, acne, scabies, sweat stain, tinea of feet and hands, onychomycosis, tinea versicolor, ringworm of the body, jock itch etc. has significant curative effect, the present invention uses vinegar for solvent, not only has the function of sterilizing, also irritating skin simultaneously, soften the effect of blood vessel, also there is the drug effect for promoting each taste Chinese medicine to play, its solvent also has the effect of long-term preservation, its irritation is also small, and it is easy to use, dosage is small, drug price is lower, product has a good application prospect.
Description
Technical field
The invention belongs to field of traditional Chinese medicine preparations, and in particular to a kind of to treat skin disease external application acetum and preparation method.
Background technique
Traditional Chinese medicine thinks have some diseases that can reflect by skin in human body, and many diseases are viscera diseases
The basic reason that external manifestation, i.e. skin occur is imbalance of yin and yang, caused by blood dirt stasis blocking, toxin buildup.But some skin diseases
It is then because fungi, bacterial skin infections etc. cause.In short, skin disease is skin（Including hair and first）Shadow by internal and external factor
After sound, form, structure and function change, and generate pathologic process, and generate various clinical successively performances accordingly.Skin
Skin disease is also the common disease for seriously affecting health of people, common skin disease have psoriasis, eczema, dermatitis, neurodermatitis,
Verruca vulgaris, anaphylaxis erythema, scabies, whelk, tinea of feet and hands, onychomycosis, tinea versicolor, ringworm of the body, jock itch etc., these skin diseases are frequent
The happy life for perplexing people, annoyings the soul and spirit of people.Accurate perfect treatment can be such that people are full of to life
Have deep love for and self-confident.Existing Chinese medicine treats skin disease, and formula has single type or limitation or medicinal material composition compatibility not to conform to
Reason, or because imperfect to the extraction of its effective component during processing or processing or extraction is unreasonable, not in place, certain
The effect of depth therapy is not achieved in degree, thus treatment is caused to be not thorough easy recurrence.There are also with regard to existing Western medicine or Chinese medicine
Different degrees of addition steroids or antibiotics, there are certain toxic side effect or are easy to produce in treatment skin disease
Antibody is not achieved treatment there are also some drugs and repairs the purpose of diseased region.It is just directed to the common curative effect office of skin disease at present
Limit undesirable, cure rate is low, recurrent exerbation, especially it is some it is common as dermatitis, neurodermatitis, acne, scabies, sweat stain,
The drug effects such as tinea of feet and hands, onychomycosis, tinea versicolor, ringworm of the body, jock itch are unobvious, stress and burden can not only be caused to patient, simultaneously
It returns patient and increases financial burden.Wang Guoqiang introduction, all tinea：Shrubalthea Bark cuts grass, each equal portions of semen momordicae.For smalls, with vinegar tune,
Painting is cured（《National Chinese herbal medicine compilation》Volume one, People's Health Publisher, in September, 2014, the third edition, page 111）.It is tested according to it
Side treatment all tineas of many cases, work well, but this method hardly result in it is universal, in order to allow vast tinea patient all to obtain very well
Therapy apparatus meeting, spy improves this side, be fabricated to it is a kind of for facilitating the product of purchase, for this purpose, exclusively carried out retrieval,
It yet there are no relevant patent application.
Summary of the invention
Skin disease external application acetum is treated in view of the deficiencies of the prior art, the present invention provides a kind of, preparing one kind has
Dermatitis, neurodermatitis, acne, scabies, tinea of feet and hands, onychomycosis, piebald caused by targetedly solving because of various bacteriums, fungi etc.
The external drug of the treatment problem of tinea, ringworm of the body, jock itch etc..
The present invention also provides the production methods for the treatment of skin tinea external application vinegar.
To achieve the goals above, the following technical solutions are specifically adopted by the present invention：
It is a kind of to treat skin disease external application acetum, which is characterized in that the 31.25g containing Shrubalthea Bark in every 1000g product cuts grass
31.25g, semen momordicae 31.25g and the vinegar of surplus composition, are made by the following method：First by Shrubalthea Bark, cut grass, semen momordicae be placed in it is close
It closes in container, it is that 75%v/v ethyl alcohol is placed under room temperature after impregnating for 24 hours under the conditions of 43 DEG C that 8 times of concentration of medicinal material total weight, which are added,
Continue dipping one week, pour out supernatant, filter, recycle ethyl alcohol, is condensed into specific gravity as the thick paste of 1.25-1.30, it is spare, then will be through
The dregs of a decoction after alcohol dipping add that 8 times of medicinal material total weight, 5 times of purifying water boiling and extraction are secondary, and decocting time is respectively respectively
2h, 1h merge secondary decoction liquor, filtering, be condensed into specific gravity be 1.25-1.30 thick paste, then respectively by alcohol extraction thick paste and
The thick paste of water boiling and extraction sequentially adds in the appropriate heated vinegar boiled, is settled to specified amount, stirs evenly, is placed in closed appearance
It in device, after placing 10 days, is filtered, dispenses, obtain product.
A kind of production method for treating skin disease external application acetum, which is characterized in that steps are as follows：
（1）Take first Shrubalthea Bark, cut grass, semen momordicae pick respectively completely, be placed in closed container, addition 8 times of medicinal material total weight
Concentration is 75%v/v ethyl alcohol, after impregnating for 24 hours under the conditions of 43 DEG C, is placed under room temperature and continues dipping one week, pour out supernatant, mistake
Ethyl alcohol is recycled in filter, is condensed into the thick paste that specific gravity is 1.25-1.30, spare；
（2）It is secondary that the dregs of a decoction after above-mentioned alcohol dipping are added into 8 times of medicinal material total weight, 5 times of purifying water boiling and extraction respectively,
Decocting time is respectively 2h, 1h, merges secondary decoction liquor, filtering, is condensed into the thick paste that specific gravity is 1.25-1.30, spare；
（3）Alcohol is extracted into thick paste respectively and water decocts the thick paste mentioned and sequentially adds in the appropriate heated vinegar boiled, is settled to rule
It is quantitative, it stirs evenly, is placed in closed container, after placing 10 days, filtered, dispense, obtain product.
Vinegar described above is brewing edible vinegar.
It is a kind of made from the method for the present invention to treat skin disease external application acetum conduct treatment dermatitis, neurodermatitis, acne, scabies
Sore, sweat stain, tinea of feet and hands, onychomycosis, tinea versicolor, ringworm of the body, the purposes of jock itch.
Shrubalthea Bark also known as corter pseudolaricis are Pinaceae gold thread pine genus plant golden larch Pseudolarix amabilis
(Nelson) root skin of Rehd..Nature and flavor are pungent, warm.It is toxic, there is dispelling wind and eliminating dampness, the antipruritic function of desinsection.Suitable for eczema, nerve
Property dermatitis, scabies.
The difference of Shrubalthea Bark medicinal material and corter pseudolaricis：Corter pseudolaricis is thick, and color is red, and shape is big；And Shrubalthea Bark is thin, color is white, there is fiber（King
Guoqiang,《National Chinese herbal medicine compilation》Volume one, People's Health Publisher, in September, 2014, the third edition, page 33）.
Grass is cut, is Chloranthaceae vegetable silk fringe tree Chloranthus fortunei（A.Gray）Solms-Lamb.
Herb or root.Nature and flavor are pungent, bitter, mild-natured.With expelling wind and activating blood flow, the efficacy of removing toxicity for detumescence energy.For rheumatic arthralgia, traumatic injury,
Boil tinea scabies, venomous snake bite.It is to cut careless herb that the present invention, which uses,.
Semen momordicae is Curcurbitaceae balsam pear platymiscium semen momordicae Momrolica cochinchinensis (Lour.)
Spreng. seed.With mass dissipating and swelling eliminating, attacks poison and treat sore function, be suitable for sore swollen toxin, acute mastitis, anal fistula, chronic eczema, the favus of the scalp.This
It is its root skin that invention, which uses,.
Beneficial effects of the present invention
The present invention is a kind of to treat skin disease external application vinegar product, and the used time is applied to affected part, to kill based on various bacteriums and fungi, and it is simultaneous
It is antipruritic to care for desinsection, has to dermatitis, neurodermatitis, acne, scabies, sweat stain, tinea of feet and hands, onychomycosis, tinea versicolor, ringworm of the body, jock itch etc.
Significant curative effect, the present invention use vinegar for solvent, not only have the function of sterilizing, while also irritating skin, soften blood
Also there is the drug effect for promoting each taste Chinese medicine to play for the effect of pipe, and solvent also has the effect of long-term preservation.The present invention is prepared into
This is low, can mitigate the financial burden of patient.The present invention treats dermopathic external application acetum for pure Chinese medicine preparation, first with second
Alcohol carries out Soakage extraction to it, its fat-soluble, volatile effective component is enable to extract, and then again mentions dregs of a decoction progress water, makes
Water soluble ingredient is sufficiently extracted, then by alcohol extracting and water mention thick paste be added vinegar in be aged, can make its traditional Chinese medicine ingredients with
The more preferable fusion of vinegar, maintains that natural drug toxicity is small, and eutherapeutic feature, curative effect is clear, using vinegar as extraction solvent,
Irritation is also small, and easy to use.External application acetum of the invention is easy to use from clinical application, and dosage is small, and have compared with
Good clinical therapeutic efficacy, patient generally gladly receive, and drug price is lower, can show present invention treatment skin disease external application
Acetum has a good application prospect.
Specific embodiment
Embodiment 1
（1）Take first Shrubalthea Bark, cut grass, semen momordicae pick respectively completely, weigh Shrubalthea Bark 31.25g, cut careless 31.25g, Momordica cochinchiensis
Sub- 31.25g, is placed in closed container, and 75%v/v ethyl alcohol 750g is added, after addition heat preservation impregnates for 24 hours under the conditions of 43 DEG C, then
It is placed under room temperature and continues dipping 1 week, pour out supernatant, filter, recycle ethyl alcohol, be condensed into the thick paste that specific gravity is 1.25, it is spare；
（2）It is placed in the dregs of a decoction after above-mentioned alcohol dipping in stainless-steel pan, purified water 750g is added, be added and decoct 2h, leaching mentions
Decoction liquor, the dregs of a decoction add purified water 468.75g, and heating decocts 1h, and leaching decoction liquor merges secondary decoction liquor, filter, concentration
The thick paste for being 1.30 at specific gravity, it is spare；
（3）It takes alcohol extraction thick paste and water to decoct the thick paste mentioned respectively, sequentially adds in the appropriate heated vinegar boiled, be settled to
1000g is stirred evenly, and is placed in closed container, after placing 10 days, is filtered, is sub-packed in 50ml vial, sealed package,
Obtain product.
Embodiment 2
（1）Take first Shrubalthea Bark, cut grass, semen momordicae pick respectively completely, weigh Shrubalthea Bark 31.25g, cut careless 31.25g, Momordica cochinchiensis
Sub- 31.25g, is placed in closed container, and 75%v/v ethyl alcohol 750g is added, after addition heat preservation impregnates for 24 hours under the conditions of 43 DEG C, then
It is placed under room temperature and continues dipping 1 week, pour out supernatant, filter, recycle ethyl alcohol, be condensed into the thick paste that specific gravity is 1.30, it is spare；
（2）It is placed in the dregs of a decoction after above-mentioned alcohol dipping in stainless-steel pan, purified water 750g is added, be added and decoct 2h, leaching mentions
Decoction liquor, the dregs of a decoction add purified water 468.75g, and heating decocts 1h, and leaching decoction liquor merges secondary decoction liquor, filter, concentration
The thick paste for being 1.25 at specific gravity, it is spare；
（3）It takes alcohol extraction thick paste and water to decoct the thick paste mentioned respectively, sequentially adds in the appropriate heated vinegar boiled, be settled to
1000g is stirred evenly, and is placed in closed container, after placing 10 days, is filtered, is sub-packed in 50ml vial, sealed package,
Obtain product.
Embodiment 3
（1）Take first Shrubalthea Bark, cut grass, semen momordicae pick respectively completely, weigh Shrubalthea Bark 31.25g, cut careless 31.25g, Momordica cochinchiensis
Sub- 31.25g, is placed in closed container, and 75%v/v ethyl alcohol 750g is added, after addition heat preservation impregnates for 24 hours under the conditions of 43 DEG C, then
It is placed under room temperature and continues dipping 1 week, pour out supernatant, filter, recycle ethyl alcohol, be condensed into the thick paste that specific gravity is 1.275, it is spare；
（2）It is placed in the dregs of a decoction after above-mentioned alcohol dipping in stainless-steel pan, purified water 750g is added, be added and decoct 2h, leaching mentions
Decoction liquor, the dregs of a decoction add purified water 468.75g, and heating decocts 1h, and leaching decoction liquor merges secondary decoction liquor, filter, concentration
The thick paste for being 1.275 at specific gravity, it is spare；
（3）It takes alcohol extraction thick paste and water to decoct the thick paste mentioned respectively, sequentially adds in the appropriate heated vinegar boiled, be settled to
1000g is stirred evenly, and is placed in closed container, after placing 10 days, is filtered, is sub-packed in 50ml vial, sealed package,
Obtain product.
Clinical efficacy：
Using the treatment skin disease external application vinegar of the embodiment of the present invention 1, scabies patient 30 are treated, wherein male 28, women 2
Example, takes local application 3 times a day, 5 days as a treatment course, and as a result a course for the treatment of cures 28, remaining 2 are treated in medication
Two course for the treatment of recoveries from illness.Cure rate 100%.
Using skin disease external application vinegar made from the embodiment of the present invention 2, dermatitis patients 5 are treated, takes local application daily
3-5 times, 5 days as a treatment course, as a result a course for the treatment of cures 3, and 2 medications, two courses for the treatment of are cured.
Using skin disease external application vinegar made from the embodiment of the present invention 3, tinea pedis patient 7 are treated, takes local application daily
3-5 times, as a result 5 days as a treatment course cure 2 for a course for the treatment of, 4 medications, two course for the treatment of recoveries from illness, 1 treatment two are treated
Journey is clearly better.
Claims (3)
1. a kind of treat skin disease external application acetum, which is characterized in that the 31.25g containing Shrubalthea Bark in every 1000g product cuts grass
31.25g, semen momordicae 31.25g and the vinegar of surplus composition, are made by the following method：First by Shrubalthea Bark, cut grass, semen momordicae be placed in it is close
It closes in container, it is that 75%v/v ethyl alcohol is placed under room temperature after impregnating for 24 hours under the conditions of 43 DEG C that 8 times of concentration of medicinal material total weight, which are added,
Continue dipping one week, pour out supernatant, filter, recycle ethyl alcohol, is condensed into specific gravity as the thick paste of 1.25-1.30, it is spare, then will be through
The dregs of a decoction after alcohol dipping add that 8 times of medicinal material total weight, 5 times of purifying water boiling and extraction are secondary, and decocting time is respectively respectively
2h, 1h merge secondary decoction liquor, filtering, be condensed into specific gravity be 1.25-1.30 thick paste, then respectively by alcohol extraction thick paste and
The thick paste of water boiling and extraction sequentially adds in the appropriate heated vinegar boiled, is settled to specified amount, stirs evenly, is placed in closed appearance
It in device, after placing 10 days, is filtered, dispenses, obtain product.
2. treatment skin disease external application acetum as described in claim 1, which is characterized in that the vinegar is brewing edible vinegar.
3. a kind of production method for treating skin disease external application acetum as described in claim 1, which is characterized in that steps are as follows：
（1）Take first Shrubalthea Bark, cut grass, semen momordicae pick respectively completely, be placed in closed container, addition 8 times of medicinal material total weight
Concentration is 75%v/v ethyl alcohol, after impregnating for 24 hours under the conditions of 43 DEG C, is placed under room temperature and continues dipping one week, pour out supernatant, mistake
Ethyl alcohol is recycled in filter, is condensed into the thick paste that specific gravity is 1.25-1.30, spare；
（2）It is secondary that the dregs of a decoction after above-mentioned alcohol dipping are added into 8 times of medicinal material total weight, 5 times of purifying water boiling and extraction respectively,
Decocting time is respectively 2h, 1h, merges secondary decoction liquor, filtering, is condensed into the thick paste that specific gravity is 1.25-1.30, spare；
（3）Alcohol is extracted into thick paste respectively and water decocts the thick paste mentioned and sequentially adds in the appropriate heated vinegar boiled, is settled to rule
It is quantitative, it stirs evenly, is placed in closed container, after placing 10 days, filtered, dispense, obtain product.
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| CN201811156544.1A CN108853173A (en) | 2018-09-30 | 2018-09-30 | It is a kind of to treat skin disease external application acetum and preparation method |
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| CN201811156544.1A CN108853173A (en) | 2018-09-30 | 2018-09-30 | It is a kind of to treat skin disease external application acetum and preparation method |
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