CN108852941A - A kind of skin care composite plant extract liquid and its preparation method and application - Google Patents
A kind of skin care composite plant extract liquid and its preparation method and application Download PDFInfo
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- CN108852941A CN108852941A CN201810988148.9A CN201810988148A CN108852941A CN 108852941 A CN108852941 A CN 108852941A CN 201810988148 A CN201810988148 A CN 201810988148A CN 108852941 A CN108852941 A CN 108852941A
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- plant extract
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
- A61K2800/5922—At least two compounds being classified in the same subclass of A61K8/18
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/74—Biological properties of particular ingredients
- A61K2800/78—Enzyme modulators, e.g. Enzyme agonists
- A61K2800/782—Enzyme inhibitors; Enzyme antagonists
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
- A61K2800/82—Preparation or application process involves sonication or ultrasonication
Abstract
The invention discloses a kind of skin care composite plant extract liquids and its preparation method and application.The skin care composite plant extract liquid, according to parts by weight, including the following raw material：5~30 parts of Flos clerodendri japonici, 5~20 parts of manchurian catalpa bark, 5~20 parts of beech mast, 2~10 parts of winter creeper, 5~20 parts of common yellowflax leaf, 5~20 parts of madder, 5~20 parts of hardwood paulownia, 5~20 parts of sophora flower, 2~10 parts of Jasmine, 2~10 parts of the fruit-rind of Chinese trichosanthes.The effective component that the present invention will be extracted from a variety of natural plants, it is safe, non-stimulated, moisturizing, whitening spot-removing, crease-resistant effect are had both, each plant component is indispensable, has the function of synergy；Skin care composite plant extract liquid of the invention is applied widely, is suitable for the makeup skin product such as lotion, facial cleanser, late frost, shower cream, toner, facial mask.
Description
Technical field
The present invention relates to cosmetic technical field, in particular to a kind of skin care composite plant extract liquid and preparation method thereof and
Using.
Background technique
With advancing age, human metabolism starts to slow down, and moisture and subcutaneous fat are reduced, and elastomer gradually becomes
Slightly, skin crumple, gloss subside, pigment deposition.Skin aging and pigment deposition are the outstanding behaviours of entire body aging, wherein
Facial skin aging is particularly evident, and fibroblastic quantity gradually decreases in human body, and the collagen and elastic force of secretion are fine
Fibrillarin also because being oxidized and gradually decreasing, be broken, just disappears to the supporting role of epidermis, cause it is inhomogenous collapse, corium
Layer beginning is thinning, and skin elasticity is deteriorated, and wrinkle also starts gradually to generate.Although skin aging is irreversible physiological phenomenon,
Its process but can delay or slow down.
The product of whitening anti-wrinkling is varied at present, and most of is chemical synthesis agent, although whitening can be played in a short time
Or crease-resistant effect, but in the long run, it is another injury again to skin.For nti-freckle product, there is Chinese medical extract
It does additive, but its effect is largely the formation for inhibiting melanin in skin, beauty can be had both a in product
White crease-resistant effect of nti-freckle will not and to skin cause any harm, and really solve the skin care of the root problem of people's skin
Product.
Summary of the invention
The purpose of the present invention is intended to provide a kind of skin care composite plant extract liquid and its preparation method and application, on solving
State technical problem.
To achieve the goals above, the technical scheme is that：
In a first aspect, a kind of skin care composite plant extract liquid provided by the invention, according to parts by weight, including it is following former
Material：5~30 parts of Flos clerodendri japonici, 5~20 parts of manchurian catalpa bark, 5~20 parts of beech mast, 2~10 parts of winter creeper, 5~20 parts of common yellowflax leaf,
5~20 parts of madder, 5~20 parts of hardwood paulownia, 5~20 parts of sophora flower, 2~10 parts of Jasmine, 2~10 parts of the fruit-rind of Chinese trichosanthes.
Preferably, the skin care composite plant extract liquid, according to parts by weight, including the following raw material：Flos clerodendri japonici 10~20
Part, 7~15 parts of manchurian catalpa bark, 10~18 parts of beech mast, 3~9 parts of winter creeper, 6~12 parts of common yellowflax leaf, 6~12 parts of madder, hardwood
7~14 parts of paulownia, 8~17 parts of sophora flower, 4~9 parts of Jasmine, 3~8 parts of the fruit-rind of Chinese trichosanthes.
Second aspect, a kind of preparation side of skin care composite plant extract liquid as described in relation to the first aspect provided by the invention
Method includes the following steps：
Above-mentioned plant is ground into powder, resulting powder is added in solvent, ultrasonic disperse is handled 1~3 hour, is obtained
The mixture is heated and is distilled, distillate is collected after condensing by mixture, and 1~3 time repeatedly, concentrated to obtain skin care compound
Plant extraction liquid.
Preferably, the solvent is selected from one of deionized water, glycerol, ethylene glycol or a variety of.
Preferably, the solvent includes deionized water, glycerol, ethylene glycol, the body of the deionized water, glycerol and ethylene glycol
Product is than being 1:0.1~0.5:0.1~0.5.
Preferably, the weight of the powder and the volume ratio of the solvent are 1:5~20 (g/mL).
Preferably, the condition of the ultrasonic disperse processing is：25~45 DEG C of temperature, 100~300W of power.
The third aspect, the skin care composite plant extract liquid of one kind provided by the invention as described in relation to the first aspect are made up in preparation
Application in product.
Preferably, any one of the cosmetics in lotion, facial cleanser, late frost, shower cream, toner, facial mask.
Compared with prior art, the beneficial effects of the present invention are：
The effective component that the present invention will be extracted from a variety of natural plants, it is safe, non-stimulated, have both moisturizing, whitening spot-removing,
Crease-resistant effect, each plant component is indispensable, has the function of synergy, water-soluble and oil-soluble small molecule in extracting solution
Active constituent is fully used, and plays the anti-oxidant of them, moisturizing, trophism comprehensively, has the blood for promoting skin
Circulation, activation and repair Skin Cell the effect of, can fundamentally improve skin generate with age and gradually it is each
Kind problem.
Skin care composite plant extract liquid of the invention is applied widely, is suitable for lotion, facial cleanser, late frost, shower cream, change
The makeup skin product such as adornment water, facial mask.
Detailed description of the invention
Fig. 1 is test result figure of each group skin care composite plant extract liquid to tyrosinase inhibition rate.
Specific embodiment
Specific embodiments of the present invention will be further explained with reference to the accompanying drawing.It should be noted that for
The explanation of these embodiments is used to help understand the present invention, but and does not constitute a limitation of the invention.In addition, disclosed below
The each embodiment of the present invention involved in technical characteristic can be combined with each other as long as they do not conflict with each other.
Embodiment 1
A kind of preparation method of skin care composite plant extract liquid provided in this embodiment, includes the following steps：
(1) following raw materials according to parts by weight are ground into powder：5 parts of Flos clerodendri japonici, 5 parts of manchurian catalpa bark, beech mast
20 parts, 10 parts of winter creeper, 20 parts of common yellowflax leaf, 5 parts of madder, 5 parts of hardwood paulownia, 20 parts of sophora flower, 10 parts of Jasmine, 10 parts of the fruit-rind of Chinese trichosanthes.
(2) by deionized water, glycerol, ethylene glycol according to 1:0.1:0.1 volume ratio is mixed into solvent, according to step (1)
The ratio of the volume of the weight and solvent of resulting powder is 1:The resulting powder of step (1) is added in solvent, surpasses by 5 (g/mL)
Sound decentralized processing 1 hour, mixture is obtained, the mixture is heated and is distilled, distillate is collected after condensing, repeatedly 1~33
It is secondary, it is concentrated to obtain skin care composite plant extract liquid；The condition of ultrasonic disperse processing is：30 DEG C of temperature, power 200W.
Embodiment 2
A kind of preparation method of skin care composite plant extract liquid provided in this embodiment, includes the following steps：
(1) following raw materials according to parts by weight are ground into powder：30 parts of Flos clerodendri japonici, 20 parts of manchurian catalpa bark, beech fruit
Real 20 parts, 2 parts of winter creeper, 5 parts of common yellowflax leaf, 5 parts of madder, 20 parts of hardwood paulownia, 20 parts of sophora flower, 2 parts of Jasmine, 2 parts of the fruit-rind of Chinese trichosanthes.
(2) by deionized water, glycerol, ethylene glycol according to 1:0.5:0.5 volume ratio is mixed into solvent, according to step (1)
The ratio of the volume of the weight and solvent of resulting powder is 1:The resulting powder of step (1) is added in solvent, surpasses by 20 (g/mL)
Sound decentralized processing 3 hours, mixture is obtained, the mixture is heated and is distilled, distillate is collected after condensing, 3 times repeatedly, warp
It is concentrated to get skin care composite plant extract liquid；The condition of ultrasonic disperse processing is：Temperature 45 C, power 300W.
Embodiment 3
A kind of preparation method of skin care composite plant extract liquid provided in this embodiment, includes the following steps：
(1) following raw materials according to parts by weight are ground into powder：10 parts of Flos clerodendri japonici, 7 parts of manchurian catalpa bark, beech mast
10 parts, 3 parts of winter creeper, 6 parts of common yellowflax leaf, 6 parts of madder, 7 parts of hardwood paulownia, 8 parts of sophora flower, 4 parts of Jasmine, 3 parts of the fruit-rind of Chinese trichosanthes.
(2) by deionized water, glycerol, ethylene glycol according to 1:0.2:0.2 volume ratio is mixed into solvent, according to step (1)
The ratio of the volume of the weight and solvent of resulting powder is 1:The resulting powder of step (1) is added in solvent, surpasses by 8 (g/mL)
Sound decentralized processing 2 hours, mixture is obtained, the mixture is heated and is distilled, distillate is collected after condensing, 3 times repeatedly, warp
It is concentrated to get skin care composite plant extract liquid；The condition of ultrasonic disperse processing is：30 DEG C of temperature, power 200W.
Embodiment 4
A kind of preparation method of skin care composite plant extract liquid provided in this embodiment, includes the following steps：
(1) following raw materials according to parts by weight are ground into powder：15 parts of Flos clerodendri japonici, 10 parts of manchurian catalpa bark, beech fruit
Real 12 parts, 4 parts of winter creeper, 10 parts of common yellowflax leaf, 8 parts of madder, 9 parts of hardwood paulownia, 10 parts of sophora flower, 5 parts of Jasmine, 4 parts of the fruit-rind of Chinese trichosanthes.
(2) by deionized water, glycerol, ethylene glycol according to 1:0.2:0.2 volume ratio is mixed into solvent, according to step (1)
The ratio of the volume of the weight and solvent of resulting powder is 1:The resulting powder of step (1) is added in solvent, surpasses by 10 (g/mL)
Sound decentralized processing 2 hours, mixture is obtained, the mixture is heated and is distilled, distillate is collected after condensing, 3 times repeatedly, warp
It is concentrated to get skin care composite plant extract liquid；The condition of ultrasonic disperse processing is：30 DEG C of temperature, power 200W.
Embodiment 5
A kind of preparation method of skin care composite plant extract liquid provided in this embodiment, includes the following steps：
(1) following raw materials according to parts by weight are ground into powder：16 parts of Flos clerodendri japonici, 12 parts of manchurian catalpa bark, beech fruit
Real 14 parts, 6 parts of winter creeper, 8 parts of common yellowflax leaf, 8 parts of madder, 12 parts of hardwood paulownia, 15 parts of sophora flower, 8 parts of Jasmine, 6 parts of the fruit-rind of Chinese trichosanthes.
(2) by deionized water, glycerol, ethylene glycol according to 1:0.3:0.2 volume ratio is mixed into solvent, according to step (1)
The ratio of the volume of the weight and solvent of resulting powder is 1:The resulting powder of step (1) is added in solvent, surpasses by 12 (g/mL)
Sound decentralized processing 2 hours, mixture is obtained, the mixture is heated and is distilled, distillate is collected after condensing, 3 times repeatedly, warp
It is concentrated to get skin care composite plant extract liquid；The condition of ultrasonic disperse processing is：35 DEG C of temperature, 100~300W of power.
Embodiment 6
A kind of preparation method of skin care composite plant extract liquid provided in this embodiment, includes the following steps：
(1) following raw materials according to parts by weight are ground into powder：20 parts of Flos clerodendri japonici, 15 parts of manchurian catalpa bark, beech fruit
Real 18 parts, 9 parts of winter creeper, 12 parts of common yellowflax leaf, 12 parts of madder, 14 parts of hardwood paulownia, 17 parts of sophora flower, 9 parts of Jasmine, 8 parts of the fruit-rind of Chinese trichosanthes.
(2) by deionized water, glycerol, ethylene glycol according to 1:0.25:0.2 volume ratio is mixed into solvent, according to step (1)
The ratio of the volume of the weight and solvent of resulting powder is 1:The resulting powder of step (1) is added in solvent, surpasses by 10 (g/mL)
Sound decentralized processing 3 hours, mixture is obtained, the mixture is heated and is distilled, distillate is collected after condensing, 3 times repeatedly, warp
It is concentrated to get skin care composite plant extract liquid；The condition of ultrasonic disperse processing is：Temperature 45 C, power 300W.
Comparative example 1
Beneficial effect in order to further illustrate the present invention is made using the preparation method similar with the embodiment of the present invention 4
The difference of skin care composite plant extract liquid, this comparative example and embodiment 1 is only that：This comparative example does not use Flos clerodendri japonici.
Comparative example 2
Beneficial effect in order to further illustrate the present invention is made using the preparation method similar with the embodiment of the present invention 4
The difference of skin care composite plant extract liquid, this comparative example and embodiment 1 is only that：This comparative example does not use madder.
Comparative example 3
Beneficial effect in order to further illustrate the present invention is made using the preparation method similar with the embodiment of the present invention 4
The difference of skin care composite plant extract liquid, this comparative example and embodiment 1 is only that：This comparative example does not use sophora flower.
Comparative example 4
Beneficial effect in order to further illustrate the present invention is made using the preparation method similar with the embodiment of the present invention 4
The difference of skin care composite plant extract liquid, this comparative example and embodiment 1 is only that：This comparative example does not use Jasmine.
Effect example 1
Crease-resistant effect of above-described embodiment 4 and the resulting skin care composite plant extract liquid of comparative example 1~4 is tested,
Testing procedure is as follows：
(1) choosing 200 experimenters is female middle-aged, and the age between 35~55 years old, carries out before experimenter is on probation
Routine inspection：Electrocardiogram, blood urine just conventional, hepatic and renal function, are showed no exception.
100 people are randomly divided into 5 groups, and every group of 40 people, wrinkle is present in forehead, eye circumference and mouth week more.
(2) after morning and evening clean skin, 1mL skin care composite plant extract liquid is uniformly applied to around eye socket at fine wrinkles, face
Cheek position and Neck wrinkles compare multiple location, and gently massage 1~2 minute, fully absorb skin, twice daily, sooner or later each
Once, it is used continuously 50 days, the trial employment period prevents solar exposure and irritation cosmetics are used with caution.
(3) result judgment criteria：
Effectively：Experimenter feels very satisfied, and face wrinkle significantly reduces, skin elasticity increase, skin shine
Increase, skin obviously bleaches；Dermatoglyph density is obviously reduced under microscope, and skin color obviously shoals.
It is effective：Experimenter feels general satisfaction, and face wrinkle is reduced substantially, and skin elasticity increases substantially, skin light
Damp degree increases substantially, and skin bleaches substantially；Dermatoglyph density slightly reduces under microscope, and skin color shoals.
In vain：Experimenter feels dissatisfied, and face wrinkle is unchanged, skin elasticity without increase, skin shine without
Increase；Dermatoglyph density is without improvement under microscope, and skin color is without improvement.
(4) measurement result is referring to table 1.
The measurement result of the crease-resistant effect of table 1
It is above-mentioned the experimental results showed that, crease-resistant effective obvious effective rate of the skin care composite plant extract liquid of the embodiment of the present invention exists
85% or more, up to 95%, anti-wrinkle effect is significant, crease-resistant effective much higher than the skin care composite plant extract liquid of comparative example
Obvious effective rate, also turning out has the function of synergy between each component of the invention.
Effect example 2
Measurement to the inhibiting effect of tyrosinase：As shown in table 2, above-described embodiment and resulting group of comparative example are taken respectively
Object is closed, is that 6.8 (1/15mol/L) phosphate buffers are settled in 25ml volumetric flask with pH, it is spare as sample solution after filtering.
Specific determination step is as follows：
(1) tyrosine 30mg is taken to be dissolved by heating with the phosphate buffer that pH is 6.8, it is molten as 0.3% tyrosine after letting cool
Liquid；Take Mushroom Tyrosinase 5mg (10000IU) plus water 50ml, filter Mushroom Tyrosinase deionized water solution (i.e.
200IU)；It is first that 6.8 phosphate buffers are reset under 475nm wavelength on ultraviolet-visible spectrophotometer with pH；
(2) taking pH is 6.8 phosphate buffer 2ml, and sample solution 2ml is added, adds 0.03% tyrosine reaction solution
2ml, mixing, shakes up, as blank control sample；
(3) sample solution 2ml is taken, the deionization of 0.03% tyrosine reaction solution 2ml and Mushroom Tyrosinase is separately added into
Aqueous solution 2ml (200IU) mixing, shakes up；As sample；
(4) taking pH is 6.8 phosphate buffer 2ml, is separately added into 0.03% tyrosine reaction solution 2ml and Mushroom Tyrosinase
Deionized water solution 2ml (200IU) mixing, shake up, as reference substance；
(5) it takes above-mentioned sample and reference substance solution (25~30 DEG C) constant-temperature incubation 30 minutes, is immediately placed on ultraviolet-visible
On spectrophotometer, absorption value is measured at 475nm wavelength；Inhibiting rate is calculated, calculation formula is as follows：Inhibiting rate (%)=
[AReference substance-(ASample-ABlank)]/(A reference substance) × 100%；Calculated result is referring to Fig. 1.
Table 2 is grouped the measurement experiment of the inhibiting effect of tyrosinase
| Group | The source of anion skin-protection alimentation composition | Volume |
| 1st group | Embodiment 1 | 1mL |
| 2nd group | Embodiment 2 | 1mL |
| 3rd group | Embodiment 3 | 1mL |
| 4th group | Embodiment 4 | 1mL |
| 5th group | Embodiment 5 | 1mL |
| 6th group | Embodiment 6 | 1mL |
| 7th group | Comparative example 1 | 1mL |
| 8th group | Comparative example 2 | 1mL |
| 9th group | Comparative example 3 | 1mL |
| 10th group | Comparative example 4 | 1mL |
Inhibit it will be seen from figure 1 that the skin care composite plant extract liquid of Examples 1 to 6 all has good tyrosinase
Effect can effectively prevent the formation of melanin to the inhibiting rate of tyrosinase in 89% or more (up to 95% or more)
And transfer, the inhibiting rate of the effect of reaching whitening from the root, tyrosinase are mentioned much higher than the skin care composite plant of comparative example
The inhibiting rate for taking liquid, also turning out has the function of synergy between each component of the invention.
In conjunction with attached drawing, the embodiments of the present invention are described in detail above, but the present invention is not limited to described implementations
Mode.For a person skilled in the art, in the case where not departing from the principle of the invention and spirit, to these embodiments
A variety of change, modification, replacement and modification are carried out, are still fallen in protection scope of the present invention.
Claims (8)
1. a kind of skin care composite plant extract liquid, which is characterized in that according to parts by weight, including the following raw material：Flos clerodendri japonici 5~30
Part, 5~20 parts of manchurian catalpa bark, 5~20 parts of beech mast, 2~10 parts of winter creeper, 5~20 parts of common yellowflax leaf, 5~20 parts of madder, hardwood
5~20 parts of paulownia, 5~20 parts of sophora flower, 2~10 parts of Jasmine, 2~10 parts of the fruit-rind of Chinese trichosanthes.
2. skin care composite plant extract liquid according to claim 1, which is characterized in that according to parts by weight, including it is as follows
Raw material：10~20 parts of Flos clerodendri japonici, 7~15 parts of manchurian catalpa bark, 10~18 parts of beech mast, 3~9 parts of winter creeper, common yellowflax leaf 6~12
Part, 6~12 parts of madder, 7~14 parts of hardwood paulownia, 8~17 parts of sophora flower, 4~9 parts of Jasmine, 3~8 parts of the fruit-rind of Chinese trichosanthes.
3. a kind of preparation method of such as skin care composite plant extract liquid according to any one of claims 1 to 2, feature exist
In including the following steps：
Above-mentioned plant is ground into powder, resulting powder is added in solvent, ultrasonic disperse is handled 1~3 hour, is mixed
The mixture is heated and is distilled, distillate is collected after condensing by object, 1~3 time repeatedly, concentrated to obtain skin care composite plant
Extracting solution.
4. skin care composite plant extract liquid according to claim 3, which is characterized in that the solvent be selected from deionized water,
One of glycerol, ethylene glycol are a variety of.
5. skin care composite plant extract liquid according to claim 4, which is characterized in that the solvent include deionized water,
Glycerol, ethylene glycol, the volume ratio of the deionized water, glycerol and ethylene glycol are 1:0.1~0.5:0.1~0.5.
6. skin care composite plant extract liquid according to claim 3, which is characterized in that the weight of the powder with it is described molten
The volume ratio of agent is 1:5~20 (g/mL).
7. skin care composite plant extract liquid according to claim 3, which is characterized in that the condition of the ultrasonic disperse processing
For：25~45 DEG C of temperature, 100~300W of power.
8. a kind of if skin care composite plant extract liquid according to any one of claims 1 to 2 is in the application prepared in cosmetics.
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| CN104739732A (en) * | 2015-04-21 | 2015-07-01 | 黄海燕 | Liquid soap used for sterilization at blood station |
| CN107744484A (en) * | 2017-11-28 | 2018-03-02 | 广西协成日用化工有限公司 | A kind of hand lotion and preparation method thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1515243A (en) * | 2003-01-03 | 2004-07-28 | 彭小航 | Fresh flower face-washing bath agent |
| CN101390818A (en) * | 2007-09-21 | 2009-03-25 | 罗蔚 | Pimple removing scream |
| CN101606895A (en) * | 2008-06-17 | 2009-12-23 | 吕炫涛 | Has plant extract skin care product of effects of wrinkle resistance, whitening and freckle removal and preparation method thereof |
| CN103948535A (en) * | 2014-05-21 | 2014-07-30 | 张贺 | Cosmetic capable of improving antioxidant capacity of skins and delaying senescence and preparation method thereof |
| CN104739732A (en) * | 2015-04-21 | 2015-07-01 | 黄海燕 | Liquid soap used for sterilization at blood station |
| CN107744484A (en) * | 2017-11-28 | 2018-03-02 | 广西协成日用化工有限公司 | A kind of hand lotion and preparation method thereof |
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Application publication date: 20181123 |