CN108850605A - A kind of feed addictive reducing diarrhea of weaned piglets - Google Patents
A kind of feed addictive reducing diarrhea of weaned piglets Download PDFInfo
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- CN108850605A CN108850605A CN201810795873.4A CN201810795873A CN108850605A CN 108850605 A CN108850605 A CN 108850605A CN 201810795873 A CN201810795873 A CN 201810795873A CN 108850605 A CN108850605 A CN 108850605A
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- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
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- A23K50/30—Feeding-stuffs specially adapted for particular animals for swines
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- A23K10/00—Animal feeding-stuffs
- A23K10/30—Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hay; from material of fungal origin, e.g. mushrooms
- A23K10/37—Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hay; from material of fungal origin, e.g. mushrooms from waste material
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/116—Heterocyclic compounds
- A23K20/121—Heterocyclic compounds containing oxygen or sulfur as hetero atom
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- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
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- A23K50/00—Feeding-stuffs specially adapted for particular animals
- A23K50/60—Feeding-stuffs specially adapted for particular animals for weanlings
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
- A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/12—Antidiarrhoeals
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Abstract
The invention discloses a kind of feed additive for weaning piglet for adding scutellarin and catechin, belong to animal nutrition and feed technical field, feed addictive of the present invention is reconciled according to a certain percentage by scutellarin and catechin, there is obvious action to the diarrhea rate for reducing weanling pig, can effectively promote the good growth and development of weanling pig.
Description
Technical field
The present invention relates to animal nutrition and feed technical fields, and in particular to a kind of wean for adding scutellarin and catechin
Additive for feed for piglets.
Background technique
Weanling pig is that can lead to weaning stress of piglet due to environment, psychology and the pressure of nutrition.In terms of environment, weanling pig
Generally it can be transferred to conservation pigsty by sow farrowing bed, external environment changes, and piglet is caused to go out the adaptation of external environment
Existing problem.Simultaneously because early weaning, the immune system of piglet is not developed completely, and the change of external environment leads to extraneous micro- life
The change of object causes piglet microorganism infection, leads to the generation of diarrhea.The feeding of psychological aspects, piglet becomes chewing from sucking,
Change in terms of behavior leads to the generation of piglet psychological stress, while re-establishing for locating group can also bring psychology to piglet
Stress, the reduction of weanling pig feed intake is caused, slow growth is caused.In terms of nutrition, the feeding of piglet becomes diet, meeting from milk
Weanling pig intestinal villi is caused to shorten, crypts is deepened, and gastric acid and digestive ferment hyposecretion, digestion power is limited, weanling pig
Nutriment can not be very likely digested and assimilated completely, lead to the generation of diarrhea.
Medicinal treatment is generally used for grice diarrhoea at present, for example Amoxicillin, electrolysis multidimensional, grape are added in water
Sugar adds cure dysentery medicine in feed.Or with intramuscular injection 10ml Diarrhoea's Killer, 10ml Ciprofloxacin Lactate, 10ml interferon, infuse respectively
It penetrates.These methods are although quick, but using excessively often having some toxic side effects, and then influence the normal development of piglet.
In recent years, as antibiotic is in the gradually disabling of livestock, people, which constantly develop, some can promote
The feed addictive of precession object growth is used to substitute antibiotics, such as Chinese herbal medicine, plant extracts and enzyme preparation etc., day
The feed addictive that right plant extracts is considered " safe, reliable, environmentally friendly " as one kind is increasingly taken seriously.
Summary of the invention
The invention discloses a kind of feed additive for weaning piglet for adding scutellarin and catechin, belong to feed processing skill
Art field, feed addictive of the present invention are reconciled according to a certain percentage by scutellarin and catechin, to reduction weanling pig
Incidence of Diarrhea has obvious action, can effectively promote the good growth and development of weanling pig.
To achieve the above object, present invention employs the following technical solutions：
A kind of feed addictive reducing diarrhea of weaned piglets, scutellarin and catechin in the active material of the feed addictive
Weight ratio is 1-10：10-1.
Further, the weight ratio of scutellarin and catechin is 1：1-9.
Further, preferred embodiment is that the weight ratio of scutellarin and catechin is 1：4.
Further, which also contains dregs of beans, and bean pulp type feed addictive, purpose is made with active material
It is that protecting effect can be played to active material, to avoid scutellarin with catechin, exposure duration too long can be because of oxygen in air
Change and do not have due effect, extends its holding time significantly.
Further, the dregs of beans is screened after drying and crushing by 20 meshes.
Further, the weight ratio of its active material and dregs of beans is 1 in the feed addictive：2-12.
Further, preferably the weight ratio of its active material and dregs of beans is 1 in the feed addictive：9.
A preferred embodiment of the invention, a kind of feed addictive of reduction diarrhea of weaned piglets, active material
By scutellarin and catechin with 1：4 weight ratio is mixed with blender.Active material and crushing dregs of beans are with 1：9 weight ratio
A kind of feed addictive for reducing diarrhea of weaned piglets is then obtained after mixing granulation, with piglet basal diet according to 1：8 matter
Amount than can be used after mixing.
Scutellaria is known as wider antimicrobial spectrum, can prevent diarrhea caused by piglet microorganism infection；Catechin is polyphenol
The effective component of class plant extracts, reduce capillary permeability can with antidiarrheal, hemostasis, it is antiviral, antifungal, to son
The enteron aisle of pig has good protecting effect, and the two compatibility can enhance piglet while killing the bacterium for leading to diarrhea and virus
Function of intestinal canal, so that it is improved itself anti-diarrhea ability, ensured growing up strong and sturdy for piglet.
Bean pulp type feed addictive can prevent scutellarin with catechin, and exposure duration too long can be due to oxidation in air
Due effect is not had, if there are the needs stored for a long time that can make its holding time with the mixed granulation of dregs of beans is crushed
Significantly extended, and a variety of amino acid that dregs of beans includes are necessary to piglet growth.
Compared with prior art, the beneficial effects of the invention are as follows：
1：Scutellarin and catechin are introduced into weanling pig feed by the invention.Wherein scutellaria is known as wider resist
Bacterium spectrum, can prevent diarrhea caused by piglet microorganism infection.Catechin is the effective component of polyphenolic plant extract, is subtracted
The permeability of few capillary can with antidiarrheal, hemostasis, it is antiviral, antifungal, have good protecting effect to the enteron aisle of piglet.
The two compatibility can enhance the function of intestinal canal of piglet while killing the bacterium for leading to diarrhea and virus, so that it is improved itself anti-
The ability of diarrhea has ensured growing up strong and sturdy for piglet.
2：Antibacterial, antivirus action existing for scutellarin and catechin simultaneously, the enteron aisle of effective protection weanling pig from
The invasion of harmful bacteria, while the immunity of weanling pig is improved, and the antibiotic added in feed a part can be substituted, thus
Improve the biological safety in breeding process.
3：Scutellarin and catechin are extracted from plant, and all-natural product, unharmful substance, without residual are belonged to
It stays.
4：Bean pulp type feed addictive, which carries out granulation, which can obviously slow down scutellarin and the oxidation rate of catechin, makes its increasing
Add the holding time.
Specific embodiment
Embodiment one, a kind of feed addictive prescription for reducing diarrhea of weaned piglets, the raw material including following parts by weight：It is living
Scutellarin and catechin are in property substance with 1：4 weight ratio is uniformly mixed with blender.It can be made into vacuum packaging.Its scutellaria
Element and catechin extraction are existing known technologies, and those skilled in the art can obtain easily, be not repeated herein.
Embodiment two, a kind of feed addictive prescription for reducing diarrhea of weaned piglets, the raw material including following parts by weight：It is living
Scutellarin and catechin are in property substance with 1：9 weight ratio is uniformly mixed with blender.It can be made into vacuum packaging.
Embodiment three, a kind of feed addictive prescription for reducing diarrhea of weaned piglets, the raw material including following parts by weight：It is living
Scutellarin and catechin are in property substance with 1：2 weight ratio is uniformly mixed with blender.It can be made into vacuum packaging.
Example IV, a kind of feed addictive prescription for reducing diarrhea of weaned piglets, the raw material including following parts by weight：It is living
Scutellarin and catechin are in property substance with 1：3 weight ratio is uniformly mixed with blender.It can be made into vacuum packaging.
Embodiment five, a kind of feed addictive prescription for reducing diarrhea of weaned piglets, the raw material including following parts by weight：It is living
Scutellarin and catechin are in property substance with 1：6 weight ratio is uniformly mixed with blender.It can be made into vacuum packaging.
Embodiment six, a kind of feed addictive prescription for reducing diarrhea of weaned piglets, the raw material including following parts by weight：It is living
Property substance in the weight ratio of scutellarin and catechin be 1：4, the weight ratio of active material and dregs of beans is 1：9.
A kind of addition scutellarin and its manufacturing method of the feed additive for weaning piglet of catechin are as follows：
One, scutellarin and catechin premix are prepared：By scutellarin and catechin with 1：4 ratio is mixed；
Two, dregs of beans material is prepared：Dregs of beans is crushed after drying, makes it through 20 mesh standard sieves；
Three, it mixes, the dregs of beans material that scutellarin configured in step 1 and catechin premix and step 2 are obtained, by 1：
9 ratios are mixed；
Four, it pelletizes：The semi-finished product come will be modulated to be pelletized with granulator, packaging can also be added appropriate before granulation
Excipient（Syrup, lard etc. can be selected in its excipient）Keep it more easily molded.
Embodiment seven, a kind of feed addictive prescription for reducing diarrhea of weaned piglets, the raw material including following parts by weight：It is living
Property substance in the weight ratio of scutellarin and catechin be 1：9, the weight ratio of active material and dregs of beans is 1：12.
A kind of addition scutellarin and its manufacturing method of the feed additive for weaning piglet of catechin are as follows：
One, scutellarin and catechin premix are prepared, by scutellarin and catechin with 1：9 ratio is mixed；
Two, dregs of beans material is prepared：Dregs of beans is crushed after drying, makes it through 20 mesh standard sieves；
Three, it mixes, the dregs of beans material that scutellarin configured in step 1 and catechin premix and step 2 are obtained, by 1：
9 ratios are mixed；
Four, it pelletizes：The semi-finished product come will be modulated to be pelletized with granulator, packaging can also be added appropriate before granulation
Excipient（Syrup, lard etc. can be selected in its excipient）Keep it more easily molded.
Embodiment eight, a kind of feed addictive prescription for reducing diarrhea of weaned piglets, the raw material including following parts by weight：It is living
Property substance in the weight ratio of scutellarin and catechin be 1：2, the weight ratio of active material and dregs of beans is 1：4.
It is a kind of addition scutellarin and catechin feed additive for weaning piglet manufacturing method it is as follows：
One, scutellarin and catechin premix are prepared, by scutellarin and catechin with 1：2 ratio is mixed；
Two, dregs of beans material is prepared：Dregs of beans is crushed after drying, makes it through 20 mesh standard sieves；
Three, it mixes, the comminuted dregs of beans that scutellarin configured in step 1 and catechin premix and step 2 are obtained is pressed
1：4 ratios are mixed；
Four, it pelletizes：The semi-finished product come will be modulated to be pelletized with granulator, packaging can also be added appropriate before granulation
Excipient（Syrup, lard etc. can be selected in its excipient）Keep it more easily molded.
Embodiment nine, a kind of feed addictive prescription for reducing diarrhea of weaned piglets, the raw material including following parts by weight：It is living
Property substance in the weight ratio of scutellarin and catechin be 1：3, the weight ratio of active material and dregs of beans is 1：8.
It is a kind of addition scutellarin and catechin feed additive for weaning piglet manufacturing method it is as follows：
One, scutellarin and catechin premix are prepared, by scutellarin and catechin with 1：3 ratio is mixed；
Two, dregs of beans material is prepared：Dregs of beans is crushed after drying, makes it through 20 mesh standard sieves；
Three, it mixes, the comminuted dregs of beans that scutellarin configured in step 1 and catechin premix and step 2 are obtained is pressed
1：8 ratios are mixed；
Four, it pelletizes：The semi-finished product come will be modulated to be pelletized with granulator, packaging can also be added appropriate before granulation
Excipient（Syrup, lard etc. can be selected in its excipient）Keep it more easily molded.
Embodiment ten, a kind of feed addictive prescription for reducing diarrhea of weaned piglets, the raw material including following parts by weight：It is living
Property substance in the weight ratio of scutellarin and catechin be 1：6, the weight ratio of active material and dregs of beans is 1：10.
It is a kind of addition scutellarin and catechin feed additive for weaning piglet manufacturing method it is as follows：
One, scutellarin and catechin premix are prepared, by scutellarin and catechin with 1：6 ratio is mixed；
Two, dregs of beans material is prepared：Dregs of beans is crushed after drying, makes it through 20 mesh standard sieves；
Three, it mixes, the comminuted dregs of beans that scutellarin configured in step 1 and catechin premix and step 2 are obtained is pressed
1：10 ratios are mixed；
Four, it pelletizes：The semi-finished product come will be modulated to be pelletized with granulator, packaging can also be added appropriate before granulation
Excipient（Syrup, lard etc. can be selected in its excipient）Keep it more easily molded.
Comparative test：
Experiment one：The difference of scutellarin and catechin the grice diarrhoea rate under different proportion of verifying.
Wean sucking pig 96 for choosing 27-28 age in days, upgrowth situation is all close, and health status is good, is randomly divided into
Quantity is 12 groups equal, 8 pigs of a small group, and every two groups are one big group, is divided into 6 groups, every group of corresponding feed of feeding.（Test number of days
It is 10 days）
First group is the piglet basal diet that normally adds as reference group.（Piglet basal diet is in the market in this experiment
The treasured product board pig starter feed that purchase comes）
Second group to the 6th group of feed is the feed addictive for five kinds of different proportions that embodiment one arrives embodiment five, difference
With 1：80 weight ratio is added piglet basal diet and stirs evenly.
Table one is verifying scutellarin and catechin the grice diarrhoea rate table of comparisons under different proportion.
Diarrhea rate（%）=（Diarrhea head number * Diarrhoea days）/（Pig's head number * tests number of days）*100
In table one as can be seen that compared with first group, the diarrhea rate of second group of piglet reduces 36.91%；Significant difference, third
The diarrhea rate of group piglet reduces 26.09%；Significant difference；The diarrhea rate of 4th group of piglet reduces 32.87%, significant difference；
The diarrhea rate of 5th group of piglet reduces 31.07%, significant difference；The diarrhea rate of 6th group of piglet reduces 27.49%, and difference is aobvious
It writes.Generally it is minimum with remaining experimental group to compare grice diarrhoea rate for embodiment one.So the weight ratio of scutellarin and catechin
It is 1：It is most preferred embodiment when 4.
Experiment two：The difference of active material and dregs of beans the grice diarrhoea rate under different proportion of verifying.
Wean sucking pig 96 for choosing 27-28 age in days, upgrowth situation is all close, and health status is good, is randomly divided into
Quantity is 12 groups equal, 8 pigs of a small group, and every two groups are one big group, is divided into 6 groups, every group of corresponding feed of feeding.（Test number of days
It is 10 days）
First group is the piglet basal diet normally added, as reference group.（Piglet basal diet is in the market in this experiment
The treasured product board pig starter feed that purchase comes）
Second group to the 6th group of feed is that embodiment six arrives five kinds of bean pulp type feed addictives of embodiment ten respectively with 1：8
Weight ratio is added piglet basal diet and stirs evenly.
Table two is the table of comparisons for verifying active material and dregs of beans the grice diarrhoea rate under different proportion.
Diarrhea rate（%）=（Diarrhea head number * Diarrhoea days）/（Pig's head number * tests number of days）*100
In table two as can be seen that compared with first group, the diarrhea rate of second group of piglet reduces 36.99%；Significant difference, third
The diarrhea rate of group piglet reduces 23.13%；Significant difference；The diarrhea rate of 4th group of piglet reduces 30.14%, significant difference；
The diarrhea rate of 5th group of piglet reduces 30.68%, significant difference；The diarrhea rate of 6th group of piglet reduces 25.54%, and difference is aobvious
It writes.Generally the bean pulp type additive diarrhea rate of second group of embodiment six is minimum, so the weight ratio of scutellarin and catechin
It is 1：4, the weight ratio of active material and dregs of beans is 1：9, it is the most preferred embodiment of bean pulp type additive.
Realize three：Further to verify dregs of beans to the protecting effect of active material.
Wean sucking pig 128 for choosing 27-28 age in days, upgrowth situation is all close, and health status is good, is randomly divided into
Quantity is 16 groups equal, 8 pigs of a small group, and every 4 groups are one big group, is divided into 4 groups, as a control group per big two groups of equal part of group, respectively
The corresponding feed of feeding.（Testing number of days is 10 days）
First group of feed is embodiment one and embodiment six respectively with 1：80 and 1：Piglet basal diet is added simultaneously in 8 weight ratio
It stirs evenly.Second group of feed is after embodiment one and embodiment six are placed five days in air respectively with 1：80 and 1：8
Weight ratio is added piglet basal diet and stirs evenly.The feed of third group is that embodiment one and embodiment six are placed in air
Respectively with 1 after ten days：80 and 1：8 weight ratio is added piglet basal diet and stirs evenly.4th group of feed is embodiment
One and embodiment six place 15 days in air after respectively with 1：80 and 1：8 weight ratio is added piglet basal diet and stirs
Uniformly.（The ratio that active material accounts in feed in above-mentioned two group is identical through conversion）
Table three is under certain time containing only scutellarin and the feed addictive of the present invention of catechin and bean pulp type feed addictive
The grice diarrhoea rate table of comparisons.
Diarrhea rate（%）=（Diarrhea head number * Diarrhoea days）/（Pig's head number * tests number of days）*100
To improve 0.12% difference not significant for the average diarrhea rate of embodiment one compared with embodiment six in the first set, second
The average diarrhea rate of embodiment one improves 9.96% significant difference compared with embodiment six in group, in third group and embodiment six
Average diarrhea rate compared to embodiment one improves 23.98% significant difference, in the 4th group of embodiment one compared with embodiment six
Average diarrhea rate improves 37.10% significant difference.
Active material protects exposed its activity in air with the increasing of time in not dregs of beans as can be seen from Table III
Add and reduce, the effect taken is worse and worse.This additive can be made not influence to make in the case where protection have a dregs of beans
It is significantly improved with the resting period in the case where effect.
In summary as can be seen that adding the porkling diarrhea rate of this feed addictive obviously than the diarrhea rate of normal diet
It is low, from experiment one as can be seen that the weight ratio of scutellarin and catechin is 1 in active material in this experiment：4 in feed
Proportion is 1：80 feed efficiency is best, and diarrhea rate is minimum.From experiment two as can be seen that scutellarin and catechin ratio mistake
Greatly, when accounting for that ratio is excessive in feed, the effect taken is declined instead.Scutellarin and catechin ratio are too small, account for feed
When middle ratio is too small, it is too small to which expected effect be not achieved to will cause diarrhea rate fall.It can be seen that from experiment three
In the case where having the protection of dregs of beans this additive resting period in the case where not influencing using effect can obtain significantly
It is promoted.
Embodiment described above is only presently preferred embodiments of the present invention, is not to make other forms to the present invention
Limitation, any those skilled in the art may be modified on the technology contents basis of the disclosure above.Without departing from this
Under the premise of inventive technique scheme content, the protection scope of technical solution of the present invention should all be fallen into.
Claims (7)
1. a kind of feed addictive for reducing diarrhea of weaned piglets, it is characterised in that the active material of the feed addictive is by scutellaria
The weight ratio of element and catechin is 1-10：10-1 composition.
2. it is according to claim 1 it is a kind of reduce diarrhea of weaned piglets feed addictive, it is characterised in that scutellarin with
The weight ratio of catechin is 1：1-9.
3. it is according to claim 1 it is a kind of reduce diarrhea of weaned piglets feed addictive, it is characterised in that scutellarin with
The weight ratio of catechin is 1：4.
4. a kind of feed addictive for reducing diarrhea of weaned piglets according to claim 1-3, it is characterised in that
The feed addictive also contains dregs of beans, and bean pulp type feed addictive is made with active material.
5. a kind of feed addictive for reducing diarrhea of weaned piglets according to claim 4, it is characterised in that the feed adds
Adding the weight ratio of its active material and dregs of beans in agent is 1：2-12.
6. a kind of feed addictive for reducing diarrhea of weaned piglets according to claim 5, it is characterised in that the feed adds
Adding the weight ratio of its active material and dregs of beans in agent is 1：9.
7. a kind of feed addictive for reducing diarrhea of weaned piglets according to claim 5 or 6, it is characterised in that the beans
The dregs of rice are screened after crushing after drying by 20 meshes.
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