CN108837058A

CN108837058A - A kind of Chinese medicine by Enem-d treatment subacute thyroiditis

Info

Publication number: CN108837058A
Application number: CN201810994345.1A
Authority: CN
Inventors: 燕树勋; 王颖; 燕翔; 郭盼盼; 万红; 党辉; 潘研; 刘琳; 陈玲; 燕苗苗; 燕炳墨; 王萍; 刘元炜; 余丹丹; 万会娜
Original assignee: Henan University of Traditional Chinese Medicine HUTCM
Current assignee: Henan University of Traditional Chinese Medicine HUTCM
Priority date: 2018-08-29
Filing date: 2018-08-29
Publication date: 2018-11-20

Abstract

The present invention relates to the Chinese medicine by Enem-d treatment subacute thyroiditis, it can effectively solve the problems, such as to improve symptom, alleviate pain, shorten the course of disease, reduce recurrence.The Chinese medicine is by poidometer：Coptis 10-20g,Radix scutellariae 10-20g,Cortex Phellodendri 15-20g,Cape jasmine 15-30g,Radix Angelicae Sinensis 20-30g,Rhizoma Chuanxiong 15-30g,Fructus Forsythiae 15-30g,Viola mandshurica 20-30g,Honeysuckle 20-30g,Radix semiaquilegiae 10-30g,Wild chrysanthemum 10-30g,Dandelion 10-30g,Prunella vulgaris 10-30g,Ramulus euonymi 10-30g,Radix ranunculi ternati 10-30g,Airpotato yam 10-15g and rhizoma dioscoreae nipponicae 15-30g are made,Above-mentioned Chinese medicine is mixed,It adds water to cook,Filtering,Filtrate is concentrated into 200-300ml,The present invention has clearing heat and detoxicating,Activating microcirculation and removing stasis medicinal,The effect of swelling and pain relieving,Subacute thyroiditis patient's cervical pain can be relieved,Enlargement is uncomfortable,The symptoms such as whole body fever,Shorten the course of disease,Improve patients ' life quality,It is the innovation on subacute thyroiditis therapeutic agent.

Description

A kind of Chinese medicine by Enem-d treatment subacute thyroiditis

Technical field

The present invention relates to medicine, especially a kind of Chinese medicine by Enem-d treatment subacute thyroiditis.

Background technique

Subacute thyroiditis is also known as granulomatous thyroiditis, giant cell thyroiditis and de Quervain first shape Adenositis is a kind of self-limited disease related with virus infection, does not stay the sequelae such as hypothyroidism generally.This disease accounts for about The 5% of thyroid disease, men and women's disease rates are 1:3—1：6, the age is mostly at 30-50 years old.The cause of disease of this disease has with virus infection It closes, such as influenza virus, Coxsackie virus, adenovirus and mumps virus.Often there are viral pharyngitis, the cheek within this onset of disease 1-3 weeks The symptom of adenositis, morbilli or other virus infections then may occur in which that obvious pain occurs for region thyreoidea, pain or radiation to ears Portion, pain aggravates or even in great pain when swallowing, and is often accompanied by poke, can also there is general malaise, appetite stimulator, muscle The symptoms such as pain, fever, tachycardia, hidrosis.Currently, western medical treatment subacute thyroiditis there is no specific aim effective ways, Therapeutic agent is mainly nonsteroidal anti-inflammatory drug and glucocorticoid.But nonsteroidal anti-inflammatory drug can cause ulcer recurrence, bronchus to be roared Breathe heavily the adverse reactions such as aggravation.Easily there is aggravation, recurrent exerbation in hormone medicine, it is difficult to cure.Recently as in The continuous progress of medical research, the efficient of this disease of Chinese traditional treatment are continuously improved.Chinese medicine thinks subacute thyroiditis category " goitre Scope bitterly " thinks this disease and the exogenous disease six external factors which cause diseases, water and soil factor, feelings though ancient Chinese medicine doctor has different understanding to this disease etiology and pathogenesis more The factors such as will internal injury are closely related.And subacute thyroiditis is divided into stage of attack and paracmasis, stage of attack Sheng, blood are stopped up with heat toxin Based on the heat folder stasis of blood；Convalescence is depressed with liver depression, based on the phlegm blood coagulation stasis of blood.Chinese medicine Enem-d belongs to for subacute thyroiditis card " heat toxin stops up Sheng, blood-head presss from both sides the stasis of blood " shows unique advantage in terms of improving symptom, alleviating pain, shortening, therefore, this Invention is succeeded in developing with actual clinical meaning.

Summary of the invention

For above situation, for the defect for solving the prior art, the purpose of the present invention is just to provide a kind of process Enem-d and controls The Chinese medicine for treating subacute thyroiditis can improve symptom, alleviate pain, shorten the course of disease, reduce recurrence, to effectively solve current The problems such as western modern medicine there is no specific aim specific medicament and individuality to react sex differernce.

The technical solution that the present invention solves is that the Chinese medicine is by poidometer：Coptis 10-20g, radix scutellariae 10-20g, Cortex Phellodendri 15- 20g, cape jasmine 15-30g, Radix Angelicae Sinensis 20-30g, Rhizoma Chuanxiong 15-30g, Fructus Forsythiae 15-30g, viola mandshurica 20-30g, honeysuckle 20-30g, Radix semiaquilegiae 10-30g, wild chrysanthemum 10-30g, dandelion 10-30g, Prunella vulgaris 10-30g, Ramulus euonymi 10-30g, radix ranunculi ternati 10- 30g, airpotato yam 10-15g and rhizoma dioscoreae nipponicae 15-30g are made, wherein mix above-mentioned Chinese medicine, add 6-8 times of Chinese medicine weight Water impregnate 30 minutes, intense fire is fried boiling, use instead and be cooked by slow fire 30 minutes, filter, obtain first time filtrate, filter residue adds Chinese medicine weight 6- 8 times of water, intense fire are fried boiling, and use instead and are cooked by slow fire 30 minutes, and filtering obtains second of filtrate, and filtrate mixing twice is concentrated into 200-300ml。

Pure Chinese medicine of the present invention is prepared, and is had the effect of clearing heat and detoxicating, activating microcirculation and removing stasis medicinal, swelling and pain relieving, can be relieved Asia Acute thyroiditis patient cervical pain, enlargement are uncomfortable, and the symptoms such as whole body fever shorten the course of disease, improve patients ' life quality, be Innovation on subacute thyroiditis therapeutic agent.

Specific embodiment

Specific embodiments of the present invention will be described in further detail with reference to embodiments.

The present invention can be provided in specific implementation by following embodiment.

Embodiment 1

A kind of Chinese medicine by Enem-d treatment subacute thyroiditis of the present invention, the Chinese medicine is by poidometer：Coptis 12- It is 18g, radix scutellariae 12-18g, Cortex Phellodendri 16-18g, cape jasmine 20-25g, Radix Angelicae Sinensis 22-28g, Rhizoma Chuanxiong 20-25g, Fructus Forsythiae 20-25g, pale reddish brown Fourth 22-28g, honeysuckle 22-28g, radix semiaquilegiae 15-25g, wild chrysanthemum 15-25g, dandelion 15-25g, Prunella vulgaris 15-25g, ghost Fletching 15-25g, radix ranunculi ternati 15-25g, airpotato yam 11-14g and rhizoma dioscoreae nipponicae 20-25g are made, wherein are blended in above-mentioned Chinese medicine Together, the water of 6-8 times of Chinese medicine weight is added to impregnate 30 minutes, intense fire is fried boiling, and uses instead and is cooked by slow fire 30 minutes, filters, and obtains for the first time Filtrate, filter residue add the water of 6-8 times of Chinese medicine weight, and intense fire is fried boiling, and use instead and are cooked by slow fire 30 minutes, and filtering obtains second of filtrate, will Filtrate mixing twice is concentrated into 200-300ml.

Embodiment 2

A kind of Chinese medicine by Enem-d treatment subacute thyroiditis of the present invention, the Chinese medicine is by poidometer：Coptis 20g, Radix scutellariae 20g, Cortex Phellodendri 20g, cape jasmine 30g, Radix Angelicae Sinensis 30g, Rhizoma Chuanxiong 30g, Fructus Forsythiae 30g, viola mandshurica 30g, honeysuckle 30g, radix semiaquilegiae 30g, wild chrysanthemum 30g, dandelion 30g, Prunella vulgaris 30g, Ramulus euonymi 30g, radix ranunculi ternati 30g, airpotato yam 15g and rhizoma dioscoreae nipponicae 30g system At, wherein above-mentioned Chinese medicine is mixed, adds the water of 6-8 times of Chinese medicine weight to impregnate 30 minutes, intense fire is fried boiling, and uses mild fire instead It decocts 30 minutes, filtering obtains first time filtrate, filter residue adds the water of 6-8 times of Chinese medicine weight, and intense fire is fried boiling, and uses instead and is cooked by slow fire 30 Minute, filtering obtains second of filtrate, and filtrate mixing twice is concentrated into 200-300ml.

Embodiment 3

A kind of Chinese medicine by Enem-d treatment subacute thyroiditis of the present invention, the Chinese medicine is by poidometer：Coptis 15g, Radix scutellariae 15g, Cortex Phellodendri 18g, cape jasmine 20g, Radix Angelicae Sinensis 25g, Rhizoma Chuanxiong 20g, Fructus Forsythiae 20g, viola mandshurica 25g, honeysuckle 25g, radix semiaquilegiae 20g, wild chrysanthemum 20g, dandelion 20g, Prunella vulgaris 20g, Ramulus euonymi 20g, radix ranunculi ternati 20g, airpotato yam 12g and rhizoma dioscoreae nipponicae 20g system At, wherein above-mentioned Chinese medicine is mixed, adds the water of 6-8 times of Chinese medicine weight to impregnate 30 minutes, intense fire is fried boiling, and uses mild fire instead It decocts 30 minutes, filtering obtains first time filtrate, filter residue adds the water of 6-8 times of Chinese medicine weight, and intense fire is fried boiling, and uses instead and is cooked by slow fire 30 Minute, filtering obtains second of filtrate, and filtrate mixing twice is concentrated into 200-300ml.

Embodiment 4

A kind of Chinese medicine by Enem-d treatment subacute thyroiditis of the present invention, the Chinese medicine is by poidometer：Coptis 10g, Radix scutellariae 10g, Cortex Phellodendri 15g, cape jasmine 15g, Radix Angelicae Sinensis 20g, Rhizoma Chuanxiong 15g, Fructus Forsythiae 15g, viola mandshurica 20g, honeysuckle 20g, radix semiaquilegiae 10g, wild chrysanthemum 10g, dandelion 10g, Prunella vulgaris 10g, Ramulus euonymi 12g, radix ranunculi ternati 12g, airpotato yam 10g and rhizoma dioscoreae nipponicae 15g system At, wherein above-mentioned Chinese medicine is mixed, adds the water of 6-8 times of Chinese medicine weight to impregnate 30 minutes, intense fire is fried boiling, and uses mild fire instead It decocts 30 minutes, filtering obtains first time filtrate, filter residue adds the water of 6-8 times of Chinese medicine weight, and intense fire is fried boiling, and uses instead and is cooked by slow fire 30 Minute, filtering obtains second of filtrate, and filtrate mixing twice is concentrated into 200-300ml.

In said components, wherein：

The coptis：Heat-clearing and damp-drying drug, purging fire for removing toxin.For damp and hot feeling of fullness, acid regurgitation is vomitted；Damp-heat dysentery；Unconsciousness due to high fever, dysphoria and insomnia, Blood-head tells nosebleed；Carbuncle swells furuncle sore, hot eyes toothache；It quenches one's thirst；Eczema, wet sore, purulent ear canal are controlled outside.

Radix scutellariae：Heat-clearing and damp-drying drug, purging fire for removing toxin, hemostasis, miscarriage prevention.For damp-warm syndrome, heat temperature, chest tightness and emesis, damp and hot feeling of fullness, jaundice Dysentery；Cough with lung heat, hyperpyrexia polydipsia.

Cortex Phellodendri：Heat-clearing and damp-drying drug, purging fire for removing toxin remove hectic fever due to yin.With under humid tropics, heat gonorrhea is puckery logical；Damp-heat dysentery, jaundice；It is damp and hot Tinea pedis, impotence card；Hectic fever due to yin labor heat, night sweat, spermatorrhea；Sore swollen toxin, eczema itch.

Cape jasmine：Purging intense heat relieving restlessness, clearing heat and promoting diuresis, removing pattogenic heat from the blood and toxic material from the body.For Vexed；Jaundice with damp-heat pathogen；Blood strangury and dry pain；Blood-head is spat Nosebleed；Red eye, swell pain；Pathogenic fire,toxin and furuncles.

Radix Angelicae Sinensis：Tonifying blood and regulating menstruation, promoting blood circulation and stopping pain, relax bowel and defecation.For all cards of the deficiency of blood；Blood deficiency and blood stasis, irregular menstruation, amenorrhoea, Dysmenorrhea；Deficient cold type abdominal pain, traumatic injury, ulcer sores, chill numbness pain.

Rhizoma Chuanxiong：Blood-activating and qi-promoting, wind-expelling pain-stopping.It is demonstrate,proved for stagnation of QI and blood pain；Headache, rheumatic arthralgia.

Fructus Forsythiae：It is clearing heat and detoxicating, dispersing swelling and dissipating binds, dispelling wind and heat from the body.For carbuncle sore tumefacting virus, scrofula subcutaneous nodule；Wind-heat exogenous disease, at the beginning of warm disease It rises；Puckery pain of heat gonorrhea.

Viola mandshurica：It is clearing heat and detoxicating, cool blood detumescence.For furuncle swelling toxin, acute mastitis acute appendicitis；Venomous snake bite.

Honeysuckle：It is clearing heat and detoxicating, dispelling wind and heat from the body.For carbuncle swells furunculosis；Affection of exogenous wind-heat, warm disease from the beginning of；Toxic-heat and blood stasis.

Radix semiaquilegiae：It is clearing heat and detoxicating, dispersing swelling and dissipating binds.For carbuncle swells furunculosis, acute mastitis, scrofula, venomous snake bite.

Wild chrysanthemum：It is clearing heat and detoxicating.Ulcer malignant boil furuncle, abscess of throat；Red eye, swell pain, headache and dizziness.

Dandelion：Clearing heat and detoxicating, dispersing swelling and dissipating binds, dampness removing is treating stranguria.For sore carbuncle serious case of furuncle, acute mastitis internal carbuncle；Puckery pain of heat gonorrhea, it is yellow Subcutaneous ulcer.

Prunella vulgaris：Clearing heat-fire, improving eyesight, mass dissipating and swelling eliminating.For red eye, swell pain, headache and dizziness, eyeball night pain；Scrofula, goitre Tumor；Acute mastitis pyogenic infections.

Ramulus euonymi：Blood-breaking, promoting menstruation, desinsection.For menostasis , Disorder lump in the abdomen, postpartum stasis abdominal pain, abdominal pain due to enterositosis.

Airpotato yam：Reducing phlegm and resolving masses disappears goitre, clearing heat and detoxicating.For goiter；Sore swollen toxin, abscess of throat, poisonous snake are healed the wounds.

Radix ranunculi ternati：Reducing phlegm and resolving masses, removing toxicity for detumescence.For scrofula subcutaneous nodule；Furunculosis, snakebite and bugbite.

Rhizoma dioscoreae nipponicae：Wind-damp dispelling, promoting blood circulation and removing obstruction in channels, clearing lung and eliminating phlegm.For rheumatism bi Zheng；Phlegm-heat cough.

Above-mentioned component science, reasonable compatibility, support mutually, have the effect of clearing heat and detoxicating, activating microcirculation and removing stasis medicinal, swelling and pain relieving, The symptoms such as subacute thyroiditis patient cervical pain, uncomfortable, the whole body fever of enlargement can be relieved, shortens the course of disease, reduces Recurrence improves patients ' life quality, good effect, drug safety, and has obtained sufficiently proving through clinical data, related clinical data It is as follows：

（One）, diagnostic criteria

Western medicine diagnostic criteria reference《Thyroid Diseases in China diagnosis and treatment guide》The diagnostic criteria of middle subacute thyroiditis, and combine Clinic is formulated.1. Thyroid Gland Swell, pain, and touch obvious；The upper respiratory tracts sense such as common fever, cough, pharyngalgia before the onset of 2. Dye, with malaise, muscle, joint pain；3. increased ESR, c reactive protein is increased；4. free serum thyroid gland original ammonia Acid（FT3）, free thyroxine（FT4）It increases, thyrotropic hormone（TSH）It reduces；5. Thyroid Intaking rate¹³¹I is substantially reduced； 6. thyroid antibody：Anti-thyroglobulin antibody（TGAb）, anti-thyroid microsomal antibody（TMAb）Or thyroid gland peroxidating Enzyme antibody（TPOAb）It is negative；7. thyroid needle or biopsy, multinucleate giant cell or granuloma change.Meet wherein four Diagnosis.

Reference《New Chinese medicine guideline of clinical investigations》Related content, in conjunction with clinical syndrome differentiation belong to initial stage, heat toxin stop up contain Card.Cardinal symptom：1. throat enlargement or lump；2. anterior cervical region pain has pain by it, there are constriction or radiating pain, turns Side is unfavorable；3. it generates heat, even shiver with cold.Minor symptom：1. palpitaition；2. hidrosis, sweating and heat do not understand；9. irritable；4. shaking It quivers；6. thirst and liking drink；8. out of strength；7. having a headache；9. limb aching pain；9. thin.Tongue vein：Red tongue body, yellow greasy, chord number or disease number or Promote.All patients for having cardinal symptom 2 and have minor symptom 3, can clarify a diagnosis in conjunction with tongue vein.

（Two）, case selection standard：

A. it is included in standard：

1. meeting above-mentioned methylene inflammation Western medicine diagnostic criteria and Chinese medical discrimination heat toxin stopping up Sheng card diagnostic criteria；

2. the age between 18-65 years old, male or female；

3. belong to the methylene inflammation patient newly diagnosed, do not treat or only with anti-inflammatory treatment patient.

Exclusion criteria：

Gestation, breast feeding women, dysfunction of liver person；It is associated with the severe primaries disease such as angiocarpy, liver, kidney and hemopoietic system Disease, mental patient；Receive other Chinese medicines, glucocorticoid and other immunosuppressant treatment persons；Other are participated in nearly March Clinical drug trial person.

（Three）, therapeutic scheme：

To the patient for being diagnosed as subacute thyroiditis, Enem-d treatment is carried out with Chinese medicine of the invention, when treatment, daily one Secondary, each 200-300ml counts therapeutic effect after 6 courses for the treatment of continuously to instill after 5 days 2 days as a treatment course of resting.

When Enem-d, by herb liquid of the present invention, it is heated up to 37-38 DEG C, is poured into spare in the medicinal liquid bottle of disinfection.Patient Left lateral position is taken, buttocks 10cm is raised, treatment towel is padded under stern, takes disposable transfusion device and cut filter, be inserted into medicinal liquid bottle Interior, with the glossy infusion apparatus front end 20-25cm of paraffin, and with paraffin oil lubrication anus, the soft infusion apparatus that is inserted into is adjusted to 16-20cm Section drips number 60-100 drop/min, and 15-30min is dripped off, and retains 10-15min.

（Four）, efficacy assessment standard：

Reference《New Chinese medicine guideline of clinical investigations》,《In State Administration of Traditional Chinese Medicine's 105 diseases of the 2nd batch of 24 professions Cure diagnosis and treatment scheme-goitre pain（Subacute thyroiditis）Chinese medicine diagnosis and treatment scheme》.

1. clinical recovery：Clinical symptoms, sign disappear or mostly disappear, Chinese medicine syndrome integral value reduce > 90%；Or phase It closes physico-chemical examination and restores normal.

2. effective：Clinical symptoms, sign have clear improvement, and goitre mitigates I degree or more, and Chinese medicine syndrome integral value subtracts Few > 70%；Related physico-chemical examination is normal.

3. effectively：Clinical symptoms, sign have improvement, and goitre mitigates I degree, and Chinese medicine syndrome integral value reduces < 70% But >=30%；Or related physico-chemical examination index makes moderate progress.

4. invalid：Clinical symptoms, sign are not improved, even aggravating, Chinese medicine syndrome integral reduces < 30%；Or phase Physico-chemical examination is closed without improvement.

Note：Chinese medicine syndrome integral calculation formula：?（Pre-treatment score-post treatment integral）/ pre-treatment score ] x100%.

（Five）, statistical procedures：

Selected patient totally 123, wherein male 33, female 90, the age is 18-65 years old.By above-mentioned（Four）Therapeutic scheme gives this Invention Chinese medicine Enem-d counts after 6 courses for the treatment of, and clinical recovery is 25 effective, 76 effective, 13 effective, and total effective rate reaches 92.7%, show that the invention Chinese medicine Enem-d treats subacute thyroiditis significant effect, has reached clinical treatment purpose, and And over the course for the treatment of, obvious adverse reaction is had no.

（Six）, typical case

For more detailed description treatment condition, the curative effect situation of typical case and treatment is given below：

1. Mr. Wang, male, 32 years old, fever was more than January repeatedly, and medical in local hospital for diagnosis with flu, curative effect is poor；Went out before 1 week Existing cervical pain, enlargement, easy sweating, red tongue body, moss thin yellow, wiry and frequent pulse.To seek systematic treating, carry out my section's treat-and-release.Physical examination： 2 degree of enlargements of thyroid gland, tenderness is obvious, and Pi Wen is increased；Auxiliary examination：First function T3, T4 are increased, and TSH is reduced；Color ultrasound prompt：First shape Body of gland product increases, and body of gland echo thickening, enhancing are distributed and owe uniformly, CDFI：Blood flow signal is shown no obvious abnormalities in body of gland；CRP: 13.7mg/L；It is diagnosed as " subacute thyroiditis ".Enem-d treatment is carried out with Chinese medicine of the invention, generate heat after 1 course for the treatment of, Cervical pain mitigates, CRP:7.8mg/L；Body temperature is normal after 3 courses for the treatment of, the slight tenderness of neck, still enlargement, CRP:5.2mg/L；6 After a course for the treatment of, have no that significant discomfort symptom, thyroid gland color ultrasound are shown no obvious abnormalities, CRP2.3mg/L.

2. Liu, female 44 years old, are diagnosed as " subacute thyroiditis " one week, subtract after local hospital infusion treatment, treatment Gently, symptom recurs after drug withdrawal；It is existing symptoms include：Cervical pain, Pi Wen are increased, and few gas is out of strength, usually short-tempered, dimly red tongue, tongue fur It is thin, rapid pulse；Auxiliary examination：First function T3, T4 are increased, and TSH is reduced；Color ultrasound prompt：Thyroid volume increases；Erythrocyte sedimentation rate：47mm/h.It looks into Body：2 degree of enlargements of thyroid gland, matter is hard, and Pi Wen is increased.Enem-d treatment is carried out with Chinese medicine of the invention, neck aches after 2 courses for the treatment of It is bitterly substantially reduced, erythrocyte sedimentation rate：15mm/h；After 6 courses for the treatment of, have no that significant discomfort symptom, thyroid gland color ultrasound are shown no obvious abnormalities, blood It is heavy：3mm/h.

3. Zhang, male, conscious discomfort of neck area before 28 years old, one week, pain, Pi Wen are increased, until local hospital is medical, it is diagnosed as " subacute thyroiditis ", oral western medicine treatment, unsatisfactory curative effect carry out my section's outpatient service for further treatment.It is existing symptoms include：Neck pain Bitterly, it generates heat, tenderness is obvious, short-tempered, and throat is even with uncomfortable, out of strength, receives deficiency of food, and sleep is general, and stool is dry, and urine is yellow；Tongue Matter is red, moss thin yellow, wiry and frequent pulse, 2 degree of enlargements of thyroid gland；Auxiliary examination：Thyroid gland color ultrasound prompts thyroid gland anthorisma；CRP: CRP:13.0mg/L.Enem-d treatment is carried out with Chinese medicine of the invention, cervical pain is substantially reduced after 1 course for the treatment of, and stool changes It is kind,；After 4 courses for the treatment of, significant discomfort symptom, 1 degree of enlargement of thyroid gland are had no；Color ultrasound is checked after 6 courses for the treatment of and first function has no obvious It is abnormal, CRP:2.9mg/L.

4. Song, female 36 years old, are diagnosed as " subacute thyroiditis " 10 days, in community clinic infusion treatment, effect is not It is good, it is existing symptoms include：Cervical pain, pressing is obvious, repeatedly low-heat, and night is obvious, and head covers, out of strength, loss of appetite, and it is poor to sleep, greatly, Urine is yellow；Red tongue body, moss thin yellow, rapid pulse;2 degree of enlargements of thyroid gland, matter is tough, and tenderness is obvious；Auxiliary examination：First function prompt FT3, FT4 obviously increases, and TSH is shown no obvious abnormalities；CRP:9.6mg/L.Enem-d treatment, 3 treatments are carried out with Chinese medicine of the invention Cervical pain is substantially reduced after journey, improvement out of strength；Color ultrasound is checked after 6 courses for the treatment of and first function is shown no obvious abnormalities, CRP：1.3mg/ L。

5. Mr. Wang, female 26 years old, generate heat 1 week repeatedly, take orally slight relief after antipyretic, after drug withdrawal repeatedly, conscious neck is not It is suitable, until outpatient clinic；It is existing symptoms include:Discomfort of neck area presses pain, and fever, burnout out of strength, two just adjust；Red tongue body, the tip of the tongue is obvious, Yellow and greasy fur, wiry and frequent pulse；1 degree of enlargement of thyroid gland, matter is hard, presses pain；Auxiliary examination：Thyroid gland color ultrasound prompts thyroid gland diffusivity Enlargement；Erythrocyte sedimentation rate：68mm/h.Enem-d treatment is carried out with Chinese medicine of the invention, cervical pain is substantially reduced after 2 courses for the treatment of, hair Heat symptom-complex shape disappears, improvement out of strength；After 4 courses for the treatment of, symptom out of strength disappears；Color ultrasound is checked after 6 courses for the treatment of and first function has no obvious different Often, erythrocyte sedimentation rate 9mm/h.

（Seven）, conclusion

Showing that the present invention is the active drug for improving subacute thyroiditis by above situation, effective percentage is 92% or more, It has no toxic side effect, curative effect is stablized, and securely and reliably, has the effect of clearing heat and detoxicating, activating microcirculation and removing stasis medicinal, swelling and pain relieving, there is actual face Bed meaning is the innovation treated on subacute thyroiditis drug, and having significantly has economic and social benefit.

Claims

1. a kind of Chinese medicine by Enem-d treatment subacute thyroiditis, which is characterized in that the Chinese medicine is by poidometer：It is yellow Even 10-20g, radix scutellariae 10-20g, Cortex Phellodendri 15-20g, cape jasmine 15-30g, Radix Angelicae Sinensis 20-30g, Rhizoma Chuanxiong 15-30g, Fructus Forsythiae 15-30g, purple Flower Chinese violet 20-30g, honeysuckle 20-30g, radix semiaquilegiae 10-30g, wild chrysanthemum 10-30g, dandelion 10-30g, Prunella vulgaris 10- 30g, Ramulus euonymi 10-30g, radix ranunculi ternati 10-30g, airpotato yam 10-15g and rhizoma dioscoreae nipponicae 15-30g are made, wherein by above-mentioned Chinese medicine It mixes, the water of 6-8 times of Chinese medicine weight is added to impregnate 30 minutes, intense fire is fried boiling, and uses instead and is cooked by slow fire 30 minutes, filters, obtains First time filtrate, filter residue add the water of 6-8 times of Chinese medicine weight, and intense fire is fried boiling, and use instead and are cooked by slow fire 30 minutes, filtering, obtain second Filtrate mixing twice is concentrated into 200-300ml by filtrate.

2. the Chinese medicine according to claim 1 by Enem-d treatment subacute thyroiditis, which is characterized in that in this Medicine is by poidometer：Coptis 12-18g, radix scutellariae 12-18g, Cortex Phellodendri 16-18g, cape jasmine 20-25g, Radix Angelicae Sinensis 22-28g, Rhizoma Chuanxiong 20- 25g, Fructus Forsythiae 20-25g, viola mandshurica 22-28g, honeysuckle 22-28g, radix semiaquilegiae 15-25g, wild chrysanthemum 15-25g, dandelion 15-25g, Prunella vulgaris 15-25g, Ramulus euonymi 15-25g, radix ranunculi ternati 15-25g, airpotato yam 11-14g and rhizoma dioscoreae nipponicae 20-25g are made, Wherein, above-mentioned Chinese medicine is mixed, adds the water of 6-8 times of Chinese medicine weight to impregnate 30 minutes, intense fire is fried boiling, and uses instead and is cooked by slow fire 30 minutes, filtering obtained first time filtrate, and filter residue adds the water of 6-8 times of Chinese medicine weight, and intense fire is fried boiling, and uses instead and is cooked by slow fire 30 minutes, Filtering, obtains second of filtrate, and filtrate mixing twice is concentrated into 200-300ml.

3. the Chinese medicine according to claim 1 by Enem-d treatment subacute thyroiditis, which is characterized in that in this Medicine is by poidometer：Coptis 20g, radix scutellariae 20g, Cortex Phellodendri 20g, cape jasmine 30g, Radix Angelicae Sinensis 30g, Rhizoma Chuanxiong 30g, Fructus Forsythiae 30g, viola mandshurica 30g, honeysuckle 30g, radix semiaquilegiae 30g, wild chrysanthemum 30g, dandelion 30g, Prunella vulgaris 30g, Ramulus euonymi 30g, radix ranunculi ternati 30g are yellow Medicine 15g and rhizoma dioscoreae nipponicae 30g are made, wherein mix above-mentioned Chinese medicine, the water of 6-8 times of Chinese medicine weight is added to impregnate 30 points Clock, intense fire are fried boiling, and use instead and are cooked by slow fire 30 minutes, and filtering obtains first time filtrate, filter residue adds the water of 6-8 times of Chinese medicine weight, intense fire It is fried boiling, uses instead and be cooked by slow fire 30 minutes, filter, obtain second of filtrate, filtrate mixing twice is concentrated into 200-300ml.

4. the Chinese medicine according to claim 1 by Enem-d treatment subacute thyroiditis, which is characterized in that in this Medicine is by poidometer：Coptis 15g, radix scutellariae 15g, Cortex Phellodendri 18g, cape jasmine 20g, Radix Angelicae Sinensis 25g, Rhizoma Chuanxiong 20g, Fructus Forsythiae 20g, viola mandshurica 25g, honeysuckle 25g, radix semiaquilegiae 20g, wild chrysanthemum 20g, dandelion 20g, Prunella vulgaris 20g, Ramulus euonymi 20g, radix ranunculi ternati 20g are yellow Medicine 12g and rhizoma dioscoreae nipponicae 20g are made, wherein mix above-mentioned Chinese medicine, the water of 6-8 times of Chinese medicine weight is added to impregnate 30 points Clock, intense fire are fried boiling, and use instead and are cooked by slow fire 30 minutes, and filtering obtains first time filtrate, filter residue adds the water of 6-8 times of Chinese medicine weight, intense fire It is fried boiling, uses instead and be cooked by slow fire 30 minutes, filter, obtain second of filtrate, filtrate mixing twice is concentrated into 200-300ml.

5. the Chinese medicine according to claim 1 by Enem-d treatment subacute thyroiditis, which is characterized in that in this Medicine is by poidometer：Coptis 10g, radix scutellariae 10g, Cortex Phellodendri 15g, cape jasmine 15g, Radix Angelicae Sinensis 20g, Rhizoma Chuanxiong 15g, Fructus Forsythiae 15g, viola mandshurica 20g, honeysuckle 20g, radix semiaquilegiae 10g, wild chrysanthemum 10g, dandelion 10g, Prunella vulgaris 10g, Ramulus euonymi 12g, radix ranunculi ternati 12g are yellow Medicine 10g and rhizoma dioscoreae nipponicae 15g are made, wherein mix above-mentioned Chinese medicine, the water of 6-8 times of Chinese medicine weight is added to impregnate 30 points Clock, intense fire are fried boiling, and use instead and are cooked by slow fire 30 minutes, and filtering obtains first time filtrate, filter residue adds the water of 6-8 times of Chinese medicine weight, intense fire It is fried boiling, uses instead and be cooked by slow fire 30 minutes, filter, obtain second of filtrate, filtrate mixing twice is concentrated into 200-300ml.