CN108836933A - A kind of preparation method of the anti-wrinkle Essence containing peony extract - Google Patents
A kind of preparation method of the anti-wrinkle Essence containing peony extract Download PDFInfo
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
- A61K8/65—Collagen; Gelatin; Keratin; Derivatives or degradation products thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
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- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9706—Algae
- A61K8/9711—Phaeophycota or Phaeophyta [brown algae], e.g. Fucus
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- A61K8/00—Cosmetics or similar toiletry preparations
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- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/98—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
- A61K8/987—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of species other than mammals or birds
- A61K8/988—Honey; Royal jelly, Propolis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
- A61K2800/805—Corresponding aspects not provided for by any of codes A61K2800/81 - A61K2800/95
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
- A61K2800/85—Products or compounds obtained by fermentation, e.g. yoghurt, beer, wine
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Abstract
A kind of preparation method of the anti-wrinkle Essence containing peony extract, belongs to Essence preparation technical field, including：Peony extract, preparation small molecule collagen polypeptide extracting solution, the preparation of water phase liquid are prepared, is emulsified, cool down and etc..The present invention is added in cosmetics using peony extract as plant additive, has effects that excellent anti-wrinkle is crease-resistant.Collagen and polypeptide can provide energy for skin, adjust intracorporal moisture, promote the synthesis and regulation of protein, enzyme, facilitate metabolism, promote cell Proliferation, differentiation, can repair cell, crease-resistant, anti-oxidant and anti-aging.
Description
Technical field
The present invention relates to Essence preparation technical field, in particular to a kind of anti-wrinkle Essence containing peony extract
Preparation method.
Background technique
Essence is the superfine product in skin care item, and ingredient is exquisite, effect is powerful, significant effect, remains what it possessed
It is noble and mysterious, it is suitable for any skin or inclined oily skin, preferably puts in the vial, take at any time.Essence is used for toner
Later, before face cream.Commonly there is poor permeability, be not easy the problems such as absorbing, and single effect in current Essence, functional
It is not strong.
Summary of the invention
It is an object of the invention to overcome the deficiencies of the prior art and provide a kind of anti-wrinkle Essence containing peony extract
Preparation method, there is good penetrability, easily absorb, the effect of anti-wrinkle.
The present invention uses following technical scheme：
A kind of preparation method of the anti-wrinkle Essence containing peony extract, includes the following steps：
Step 1：Brown sugar is dissolved in the water, brown sugar water is obtained, new fresh peong flower is added in brown sugar water and is uniformly mixed,
Obtain fermentation substrate, the weight ratio of the peony and brown sugar water is 1:6, fermentation substrate is fitted into ceramic cylinder, in 30-37
DEG C condition lower sealing ferments 48-60 hour, obtains tunning, and water stirring 20-30 minutes is added into tunning, described
The mass ratio of tunning and water is 1:6, solid A and liquid B is obtained by filtration, mixes to obtain mixing after solid A is crushed with liquid B
The granularity of liquid, crushing is 40-60 mesh, then mixed liquor is carried out ultrasonication, and wherein ultrasonic power is 150-200w, and frequency is
30-35Hz, ultrasonic time 10-15min are centrifugally separating to obtain liquid C, liquid C are carried out microwave sterilization, the time is 2-5 points
Clock, temperature obtain peony extract at 70-80 DEG C；
Step 2：It is first impregnated fish-skin bone 30 seconds with the ethyl alcohol of mass concentration 60-80%, then is carefully cleaned with clear water, removed
Fats impurity cuts disrupting tissue with knife later, and water elutes 3 times, then presses fish-skin bone and water quality than 1:5 ratio impregnates fish-skin
Bone adjusts pH value to 6.9-8.5, is heated to 100 degree, keeps the temperature 1 hour, be cooled to water temperature 40-50 degree, use 150- later
300 mesh filter 2-3 times, obtain macromolecular collagen protein extracting solution, and wherein collagen content is 0.05-1g/ml；
Step 3：Macromolecular collagen protein extracting solution is digested with biological enzyme, biological enzyme used is stomach cardia
Enzyme, concentration 0.0001-500mg/ml digest within 24 hours, are put into 90 DEG C of water-baths and be cooled to room temperature after destroying enzyme activity, from
Heart processing, 4500-10000rpm are centrifugated 30-10min, finally take supernatant, obtain small molecule collagen polypeptide extracting solution,
Middle collagen polypeptide content is 0.05-1g/ml；
Step 4：It weighs in deionized water to water phase pot, sequentially adds the measured EDETATE SODIUM of accurate scale, hyaluronic acid
Sodium, carbomer, and heating mixes while stirring, is sufficiently stirred and is uniformly dissolved under temperature 60 C, sequentially adds propylene glycol, 1,3-
Butanediol, methyl hydroxybenzoate, allantoin, temperature 60 C keep the temperature 30 minutes；
Step 5：Material in water phase pot is pumped into vacuum emulsifying pot, tree peony extraction is sequentially added under stirring
Object, small molecule collagen polypeptide extracting solution, propolis extract, protease, aminopeptidase, camomile extract, licorice, ferment
Female polypeptide, tip edge bladder-wrack extract, oligopeptides -20 stir 30 minutes, are sufficiently mixed uniformly；
Step 6：It cools, when temperature drops to 45 DEG C, Cremophor RH40, blumea oil, octanoic acid is added
Glyceride, and stir；
Step 7：Continue to cool down, when temperature drops to 35 DEG C, aminomethyl propanol is added, and stir, then cold
But to room temperature to get Essence.
Preferably, the propolis extract is nanometer supercritical bee-glue.
It is further preferred that the nanometer supercritical bee-glue is the nanometer being process by Phospholipids nano-encapsulated technology
Supercritical bee-glue.
Preferably, the licorice is prepared using following methods：5g licorice medicinal materials are crushed, sieving, obtains powder
The NaOH aqueous solution that concentration is 0.2mol/L is added in body, is 1 by solid-to-liquid ratio:The mixing of 10 ratios, 2h is extracted in hot dipping at 80 DEG C,
It is repeated 2 times, filters, it is 3% hydrochloric acid tune pH value to 1-2.5 that mass concentration is added in filtrate, is centrifuged under the revolving speed of 4000r/min
Separation, goes supernatant to obtain sediment, as licorice.
Preferably, the camomile extract is prepared using following methods：5g chamomile is crushed, sieving, obtains powder
The NaOH aqueous solution that concentration is 0.2mol/L is added in body, is 1 by solid-to-liquid ratio:The mixing of 10 ratios, 2h is extracted in hot dipping at 80 DEG C,
It is repeated 2 times, filters, it is 3% hydrochloric acid tune pH value to 1-2.5 that mass concentration is added in filtrate, is centrifuged under the revolving speed of 4000r/min
Separation, goes supernatant to obtain sediment, as camomile extract.
Preferably, the tip edge bladder-wrack extract is prepared using following methods：Tip edge bladder-wrack is washed, is put
It sets and is carried out at aeration-drying air-dried, the tip edge bladder-wrack after air-drying is placed in micro-wave oven, the dry 4min of moderate heat, after drying
Tip edge bladder-wrack be put into pulverizer and crush, smashed tip edge bladder-wrack is crossed into 60 meshes, tip edge bladder-wrack powder is obtained, weighs
Tip edge bladder-wrack powder 10g, deionized water 100g, are added to the container, and decoct at 90 DEG C and extract 100min, by the substance in container
It all takes out, is cooled to room temperature, filtered with cryogenic freezing centrifuge, revolving speed 3000r/min, centrifugation time 5min, in collection
Clear liquid obtains tip edge bladder-wrack extract after filtering.
It is further preferred that described is filtered into three layers of filtered through gauze.
It is further preferred that being filtered after three layers of filtered through gauze using the membrane filter in 0.2 μm of aperture.
Preferably, the grinding and sieving was 40 meshes.
The beneficial effects of the present invention are：
1) peony extract is added in cosmetics as plant additive, has effects that excellent anti-wrinkle is crease-resistant.
2) collagen and polypeptide can provide energy for skin, adjust intracorporal moisture, promote the synthesis of protein, enzyme
With regulation, facilitate metabolism, promote cell Proliferation, differentiation, can repair cell, it is crease-resistant, anti-oxidant and delay senescence.
3) the effect of Radix Glycyrrhizae has clearing heat and detoxicating, antibacterial anti-inflammatory, is suitble to various skin, is particularly suitable for sensibility skin, ocean
Camomile have disinfecting, antimicrobial, releive sensitive skin the effect of.
4) present invention uses nanometer supercritical bee-glue, it is easy to which infiltration and absorption successfully solve and other ingredients
Compatibility issues, nanometer supercritical bee-glue have the function of that strength is anti-oxidant, inhibit tyrosinase activity, and whitening spot-removing effect is aobvious
It writes.
5) natural nutrient needed for tip edge bladder-wrack can provide skin rapid regeneration and cell normal growth, extra-nutrition
It is lost, promotes skin metabolism, increase skin energy element ATP synthesis；It protects skin cell mitochondria and maintains mitochondria function
Energy；Promote skin revitalization, skin is helped to reply health and vigor.
Specific embodiment
With reference to embodiments, the technical solution in the present invention is clearly and completely described.Based in the present invention
Embodiment, every other embodiment obtained by those of ordinary skill in the art without making creative efforts, all
Belong to the scope of protection of the invention.
A kind of anti-wrinkle Essence containing peony extract, the raw material including following parts by weight：2-4 portions of tree peonies extract
Object, 2-4 parts of small molecule collagen polypeptide extracting solutions, 2-4 parts of propolis extracts, 0.5-1 parts of protease, 0.5-1 parts of aminopeptidases, 1-
2 parts of camomile extracts, 1-2 parts of licorices, 1-3 parts of yeast polypeptides, 2-4 parts of tip edge bladder-wrack extracts, 1-3 parts of widows
Peptide -20,0.5-1 part carbomer, 0.6-2 parts of aminomethyl propanols, 3-6 parts of propylene glycol, 3-6 parts of 1,3 butylene glycols, 0.5-1 parts of PEG-
40 rilanit specials, 0.5-1 part blumea oil, 0.5-1 parts of glycerol caprylates, 0.1-0.2 parts of methyl hydroxybenzoates, 0.1-0.2 parts of urine
Bursin, 0.02-0.1 part EDETATE SODIUM, 0.03-0.1 parts of Sodium Hyaluronates, 70-100 parts of deionized waters.
A kind of preparation method of the anti-wrinkle Essence containing peony extract, includes the following steps：
Step 1：Brown sugar is dissolved in the water, brown sugar water is obtained, new fresh peong flower is added in brown sugar water and is uniformly mixed,
Obtain fermentation substrate, the weight ratio of the peony and brown sugar water is 1:6, fermentation substrate is fitted into ceramic cylinder, in 30-37
DEG C condition lower sealing ferments 48-60 hour, obtains tunning, and water stirring 20-30 minutes is added into tunning, described
The mass ratio of tunning and water is 1:6, solid A and liquid B is obtained by filtration, mixes to obtain mixing after solid A is crushed with liquid B
The granularity of liquid, crushing is 40-60 mesh, then mixed liquor is carried out ultrasonication, and wherein ultrasonic power is 150-200w, and frequency is
30-35Hz, ultrasonic time 10-15min are centrifugally separating to obtain liquid C, liquid C are carried out microwave sterilization, the time is 2-5 points
Clock, temperature obtain peony extract at 70-80 DEG C；
Step 2：It is first impregnated fish-skin bone 30 seconds with the ethyl alcohol of mass concentration 60-80%, then is carefully cleaned with clear water, removed
Fats impurity cuts disrupting tissue with knife later, and water elutes 3 times, then presses fish-skin bone and water quality than 1:5 ratio impregnates fish-skin
Bone adjusts pH value to 6.9-8.5, is heated to 100 degree, keeps the temperature 1 hour, be cooled to water temperature 40-50 degree, use 150- later
300 mesh filter 2-3 times, obtain macromolecular collagen protein extracting solution, and wherein collagen content is 0.05-1g/ml；
Step 3：Macromolecular collagen protein extracting solution is digested with biological enzyme, biological enzyme used is stomach cardia
Enzyme, concentration 0.0001-500mg/ml digest within 24 hours, are put into 90 DEG C of water-baths and be cooled to room temperature after destroying enzyme activity, from
Heart processing, 4500-10000rpm are centrifugated 30-10min, finally take supernatant, obtain small molecule collagen polypeptide extracting solution,
Middle collagen polypeptide content is 0.05-1g/ml；
Step 4：It weighs in deionized water to water phase pot, sequentially adds the measured EDETATE SODIUM of accurate scale, hyaluronic acid
Sodium, carbomer, and heating mixes while stirring, is sufficiently stirred and is uniformly dissolved under temperature 60 C, sequentially adds propylene glycol, 1,3-
Butanediol, methyl hydroxybenzoate, allantoin, temperature 60 C keep the temperature 30 minutes；
Step 5：Material in water phase pot is pumped into vacuum emulsifying pot, tree peony extraction is sequentially added under stirring
Object, small molecule collagen polypeptide extracting solution, propolis extract, protease, aminopeptidase, camomile extract, licorice, ferment
Female polypeptide, tip edge bladder-wrack extract, oligopeptides -20 stir 30 minutes, are sufficiently mixed uniformly；
Step 6：It cools, when temperature drops to 45 DEG C, Cremophor RH40, blumea oil, octanoic acid is added
Glyceride, and stir；
Step 7：Continue to cool down, when temperature drops to 35 DEG C, aminomethyl propanol is added, and stir, then cold
But to room temperature to get Essence.
The propolis extract is nanometer supercritical bee-glue.The nanometer supercritical bee-glue is wrapped by Phospholipids nanometer
The nanometer supercritical bee-glue that the technology of wrapping up in is process.
The licorice is prepared using following methods：5g licorice medicinal materials are crushed, sieving, obtain powder, is added
Concentration is the NaOH aqueous solution of 0.2mol/L, is 1 by solid-to-liquid ratio:The mixing of 10 ratios, 2h is extracted in hot dipping at 80 DEG C, is repeated 2 times,
It filters, it is 3% hydrochloric acid tune pH value to 1-2.5 that mass concentration is added in filtrate, is centrifugated, goes under the revolving speed of 4000r/min
Supernatant obtains sediment, as licorice.
The grinding and sieving was 40 meshes.
The camomile extract is prepared using following methods：5g chamomile is crushed, sieving, obtain powder, is added
Concentration is the NaOH aqueous solution of 0.2mol/L, is 1 by solid-to-liquid ratio:The mixing of 10 ratios, 2h is extracted in hot dipping at 80 DEG C, is repeated 2 times,
It filters, it is 3% hydrochloric acid tune pH value to 1-2.5 that mass concentration is added in filtrate, is centrifugated, goes under the revolving speed of 4000r/min
Supernatant obtains sediment, as camomile extract.
The grinding and sieving was 40 meshes.
The tip edge bladder-wrack extract is prepared using following methods：Tip edge bladder-wrack is washed, is placed on logical
It air-dries dry place and carries out air-dried, the tip edge bladder-wrack after air-drying is placed in micro-wave oven, the dry 4min of moderate heat, by the tip edge after drying
Bladder-wrack is put into pulverizer and crushes, and smashed tip edge bladder-wrack is crossed 60 meshes, obtains tip edge bladder-wrack powder, weighs tip edge ink
Angle algae powder 10g, deionized water 100g, are added to the container, and decoct at 90 DEG C and extract 100min, the substance in container is all taken
Out, it is cooled to room temperature, is filtered with cryogenic freezing centrifuge, revolving speed 3000r/min, centrifugation time 5min, supernatant, mistake are collected
After filter tip edge bladder-wrack extract, it is described to be filtered into three layers of filtered through gauze, using 0.2 after three layers of filtered through gauze
The membrane filter filtering in μm aperture.
The present invention is exemplarily described above, it is clear that present invention specific implementation is not subject to the restrictions described above,
As long as using the improvement for the various unsubstantialities that the inventive concept and technical scheme of the present invention carry out, or not improved this is sent out
Bright conception and technical scheme directly apply to other occasions, within the scope of the present invention.Protection of the invention
Range should be determined by the scope of protection defined in the claims.
Claims (9)
1. a kind of preparation method of the anti-wrinkle Essence containing peony extract, which is characterized in that include the following steps：
Step 1：Brown sugar is dissolved in the water, brown sugar water is obtained, new fresh peong flower is added in brown sugar water and is uniformly mixed, is obtained
The weight ratio of fermentation substrate, the peony and brown sugar water is 1:6, fermentation substrate is fitted into ceramic cylinder, in 30-37 DEG C of item
Part lower sealing ferments 48-60 hours, obtains tunning, and water is added into tunning and stirs 20-30 minutes, the fermentation
The mass ratio of product and water is 1:6, solid A and liquid B is obtained by filtration, mixes to obtain mixed liquor with liquid B after solid A is crushed,
The granularity of crushing is 40-60 mesh, then mixed liquor is carried out ultrasonication, and wherein ultrasonic power is 150-200w, frequency 30-
35Hz, ultrasonic time 10-15min are centrifugally separating to obtain liquid C, and liquid C is carried out microwave sterilization, and the time is 2-5 minutes,
Temperature obtains peony extract at 70-80 DEG C；
Step 2：It is first impregnated fish-skin bone 30 seconds with the ethyl alcohol of mass concentration 60-80%, then is carefully cleaned with clear water, removal fat
Class impurity cuts disrupting tissue with knife later, and water elutes 3 times, then presses fish-skin bone and water quality than 1:5 ratio impregnates fish-skin bone,
PH value is adjusted to 6.9-8.5,100 degree is heated to, keeps the temperature 1 hour, be cooled to water temperature 40-50 degree, use 150-300 later
Mesh filters 2-3 times, obtains macromolecular collagen protein extracting solution, and wherein collagen content is 0.05-1g/ml；
Step 3：Macromolecular collagen protein extracting solution is digested with biological enzyme, biological enzyme used is pepsin, dense
Degree is 0.0001-500mg/ml, digest within 24 hours, puts into 90 DEG C of water-baths and is cooled to room temperature after destroying enzyme activity, at centrifugation
Reason, 4500-10000rpm are centrifugated 30-10min, finally take supernatant, obtain small molecule collagen polypeptide extracting solution, wherein glue
Former content of peptides is 0.05-1g/ml；
Step 4：Weigh in deionized water to water phase pot, sequentially add the measured EDETATE SODIUM of accurate scale, Sodium Hyaluronate,
Carbomer, and heating mixes while stirring, is sufficiently stirred and is uniformly dissolved under temperature 60 C, sequentially adds propylene glycol, 1,3- fourth
Glycol, methyl hydroxybenzoate, allantoin, temperature 60 C keep the temperature 30 minutes；
Step 5：It material will be pumped into vacuum emulsifying pot in water phase pot, peony extract, small is sequentially added under stirring
Molecule collagen polypeptide extracting solution, propolis extract, protease, aminopeptidase, camomile extract, licorice, yeast are more
Peptide, tip edge bladder-wrack extract, oligopeptides -20 stir 30 minutes, are sufficiently mixed uniformly；
Step 6：It cools, when temperature drops to 45 DEG C, Cremophor RH40, blumea oil, sad glycerol is added
Ester, and stir；
Step 7：Continue to cool down, when temperature drops to 35 DEG C, aminomethyl propanol is added, and stir, is cooled to
Room temperature is to get Essence.
2. a kind of preparation method of anti-wrinkle Essence containing peony extract according to claim 1, it is characterised in that：
The propolis extract is nanometer supercritical bee-glue.
3. a kind of preparation method of anti-wrinkle Essence containing peony extract according to claim 2, it is characterised in that：
The nanometer supercritical bee-glue is the nanometer supercritical bee-glue being process by Phospholipids nano-encapsulated technology.
4. a kind of preparation method of anti-wrinkle Essence containing peony extract according to claim 1, which is characterized in that
The licorice is prepared using following methods：5g licorice medicinal materials are crushed, sieving, obtain powder, concentration, which is added, is
The NaOH aqueous solution of 0.2mol/L is 1 by solid-to-liquid ratio:The mixing of 10 ratios, 2h is extracted in hot dipping at 80 DEG C, is repeated 2 times, and is filtered,
It is 3% hydrochloric acid tune pH value to 1-2.5 that mass concentration is added in filtrate, is centrifugated under the revolving speed of 4000r/min, removes supernatant
Obtain sediment, as licorice.
5. a kind of preparation method of anti-wrinkle Essence containing peony extract according to claim 1, which is characterized in that
The camomile extract is prepared using following methods：5g chamomile is crushed, sieving, obtain powder, concentration, which is added, is
The NaOH aqueous solution of 0.2mol/L is 1 by solid-to-liquid ratio:The mixing of 10 ratios, 2h is extracted in hot dipping at 80 DEG C, is repeated 2 times, and is filtered,
It is 3% hydrochloric acid tune pH value to 1-2.5 that mass concentration is added in filtrate, is centrifugated under the revolving speed of 4000r/min, removes supernatant
Obtain sediment, as camomile extract.
6. a kind of preparation method of anti-wrinkle Essence containing peony extract according to claim 1, which is characterized in that
The tip edge bladder-wrack extract is prepared using following methods：Tip edge bladder-wrack is washed, is placed at aeration-drying
Carry out air-dried, the tip edge bladder-wrack after air-drying is placed in micro-wave oven, and the dry 4min of moderate heat puts the tip edge bladder-wrack after drying
Enter in pulverizer and crush, smashed tip edge bladder-wrack is crossed into 60 meshes, obtains tip edge bladder-wrack powder, weighs tip edge bladder-wrack powder
10g, deionized water 100g, are added to the container, and decoct at 90 DEG C and extract 100min, the substance in container are all taken out, drop
It warms to room temperature, is filtered with cryogenic freezing centrifuge, revolving speed 3000r/min, centrifugation time 5min, supernatant is collected, after filtering
Obtain tip edge bladder-wrack extract.
7. a kind of preparation method of anti-wrinkle Essence containing peony extract according to claim 6, it is characterised in that：
Described is filtered into three layers of filtered through gauze.
8. a kind of preparation method of anti-wrinkle Essence containing peony extract according to claim 7, it is characterised in that：
It is filtered after three layers of filtered through gauze using the membrane filter in 0.2 μm of aperture.
9. a kind of preparation method of anti-wrinkle Essence containing peony extract according to claim 4 or 5, feature exist
In：The grinding and sieving was 40 meshes.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810831873.5A CN108836933A (en) | 2018-07-26 | 2018-07-26 | A kind of preparation method of the anti-wrinkle Essence containing peony extract |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201810831873.5A CN108836933A (en) | 2018-07-26 | 2018-07-26 | A kind of preparation method of the anti-wrinkle Essence containing peony extract |
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| CN108836933A true CN108836933A (en) | 2018-11-20 |
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| CN201810831873.5A Withdrawn CN108836933A (en) | 2018-07-26 | 2018-07-26 | A kind of preparation method of the anti-wrinkle Essence containing peony extract |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109331074A (en) * | 2018-12-24 | 2019-02-15 | 广州环亚化妆品科技有限公司 | A kind of Chinese medicine composition and its preparation method and application with senile-resistant efficacy |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109331074A (en) * | 2018-12-24 | 2019-02-15 | 广州环亚化妆品科技有限公司 | A kind of Chinese medicine composition and its preparation method and application with senile-resistant efficacy |
| CN109331074B (en) * | 2018-12-24 | 2021-09-24 | 广州环亚化妆品科技有限公司 | Traditional Chinese medicine composition with anti-aging effect and preparation method and application thereof |
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Application publication date: 20181120 |