CN1088100A

CN1088100A - Be used for giving protection against cancer, controlling the processing technology of cancer herb liquid " true man of Xingan soup "

Info

Publication number: CN1088100A
Application number: CN 92114048
Authority: CN
Inventors: 何承恕
Original assignee: Individual
Current assignee: Individual
Priority date: 1992-12-17
Filing date: 1992-12-17
Publication date: 1994-06-22

Abstract

The present invention relates to a kind of processing technology that is used for anti-cancer, controls cancer herb liquid " true man of Xingan soup ".It dries in the shade the Chinese herbal medicine of gathering between given period to shred to merge and decocts, cools off after secondary decocts, filters, be the processing technology of finished product again after secondary precipitation, fill, high-temperature sterilization, cooling.This invention all adopts that natural plants is that raw material, equipment are simple, small investment, instant effect.Adopt the herb liquid of the present invention's making efficient, have no side effect.The main feature of clinical treatment is that the removing blood stasis, cancer pain, abdominal distention to hepatocarcinoma, weak, ascites, hyperpyrexia are all effective in cure, suppresses the carcinoma growth.Suppress the cancerometastasis aspect system, comprehensive, specificity curative effect are arranged." true man of Xingan soup " is 1-7 days to the onset cycle of hepatocarcinoma clinical symptoms, and it is 7-15 days that the tumor body suppresses the onset cycle.It is 10-30 minutes that hemorheology index improves the onset cycle.

Description

Be used for giving protection against cancer, controlling the processing technology of cancer herb liquid " true man of Xingan soup "

The present invention relates to a kind of processing technology of herb liquid, specifically be used for giving protection against cancer, controlling the processing technology of cancer herb liquid " true man of Xingan soup ".Be mainly used in the control of internal organs entity occupy-place malignant tumor.Prevention, treatment to primary hepatocarcinoma have specially good effect.

Primary hepatocarcinoma (abbreviation hepatocarcinoma) is known as the king in the cancer, is a great problem of current tumor medical science, belongs to internal organs entity occupy-place malignant tumor.2/5ths death is in removing blood stasis, and 70-85% is with fat sclerosis, and the patient that sends out of 60-80% is taken place in 45-54 year crowd.Existing liver cancer treatment means have operative therapy, put, chemotherapy, anhydrous alcohol injection.Clarke cellular immunization decant(-ation) method, the traditional Chinese medical science, Chinese medicine, QI GONG therapy etc. are more than tens kinds.Early stage small liver cancer with methods such as AFP, CT are generally investigated out through medical institutions' treatment, has reached the survival ratio about 60%, 40%, 25% life cycle in 1 year, 3 years, 5 years respectively.During but the most patients that outpatient service is made a definite diagnosis has belonged to, late period, the operation possibility of success has certain limitation.Patient's removing blood stasis in this stage, abdominal distention, weak, cancer pain, ascites, liver blood flow varying cyclically, hepatic necrosis, liver failure, microcirculation blood flow obstacle, fever, cancer growth, cancerometastasis, blood viscosity increasing, cancer embolus, thrombosis are shaped, numerous hepatocarcinoma causes of disease, the side effect that how pathological factor is accurately diagnosed and the high amount of drug merging is used, treated and produces and nocuity or the like are still the difficult problem that current tumor medical science is endeavoured to capture.

A kind of preparation technology who is used for anti-cancer, controls cancer herb liquid " true man of Xingan soup " that purpose of the present invention provides at the problems referred to above just.

The herb liquid of being made by the present invention is efficient, have no side effect, low toxicity, and is adapted to the treatment of the full course of disease different phase of hepatocarcinoma.Process is simple and easy to do, and crude drug source is abundant, and small investment takes effect obviously.

The objective of the invention is to realize by following measure:

The chopping of drying in the shade of the Chinese herbal medicine that will gather in special time adds various decoction pieces and puts into aluminum pot or marmite, adds water and boils and boil, filter, add water and boil and boil, filter; The medicinal liquid of twice decoction is merged, decocts postcooling, again through twice precipitation successively, fill behind the sediment exclusion, seal, autoclave sterilization, the cooling back.

Adopt the present invention can make " true man of Xingan soup " herb liquid form industrialization, commercialization production.The retention cycle of medicine never degenerated, did not lose efficacy in 2 years.Because the source of medicine is that Daxing'an Mountainrange wild plant medical material is main, pollution-free, and aboundresources.This processing technology cycle is short, and equipment investment is few, output is high.

Below the present invention is done detailed description:

1. the Herba Taraxaci in 5-8 month of gathering does not have colored herb and cleans earth and dry in the shade standby; The gather Radix Astragali, Calyx seu fructus physalis, the Radix Sanguisorbae (Da Ye Radix Sanguisorbae) in 6-7 month, the ground herb of Herba Leonuri dried in the shade standby; Gather Flos Chrysanthemi Indici, the Flos Inulae in 7-8 month, the ground herb (with the Hua Weijia that just opens) of Radix Cirsii Japonici dries in the shade standby.

2. above-mentioned crude drug is claimed to decide in proportion weight (accurately to gram): Radix Astragali 5-10 part, Radix Sanguisorbae 1-6 part, Calyx seu fructus physalis 1-5 part, Radix Salviae Miltiorrhizae 1-4 part, Radix Isatidis 1-8 part, Radix Cirsii Japonici 2-6 part, Radix Adenophorae (Radix Glehniae) 1-3 part, Radix Ophiopogonis 1-3 part, Radix Rehmanniae Preparata 1-3 part, Flos Chrysanthemi Indici 1-5 part, Cortex Moutan 1-2 part, Radix Paeoniae Alba 1-3 part, Poria 1-3 part, Flos Inulae 1-3 part, Radix Codonopsis 1-3 part, Radix Puerariae 1-4 part, Fructus Schisandrae Chinensis 1-5 part, Fructus Lycii 1-5 part, Herba Taraxaci 1-4 part, Herba Hedyotidis Diffusae 1-8 part, Herba Scutellariae Barbatae 1-6 part, Herba Leonuri 2-3 part, Radix Rubiae 1-4 part.

3. earlier aluminum pot or marmite are put in herb chopping and other decoction pieces simultaneously, added water to the above 5cm of medicine layer.Back the boiling with the heating of temperature fire that stir boiled about 30 minutes.Filter rapidly with device for drying and filtering.Medicine after the filter adds water to the medicine layer again and decocted 20 minutes with the temperature fire, filters rapidly with device for drying and filtering.

4. merge behind the medicinal liquid sediment exclusion with twice decoction.Boil with moderate heat heating and to boil 15-20 minute.Cooling was left standstill 6-12 hour, stirs evenly fill behind the eliminating visible precipitate thing and (need the sterile working) in 500 milliliters vial.Bottleneck is adorned thin film, top cement plug, jewelling lid.Place in the high pressure sterilizer, with greater than 126 ℃ autoclave sterilization 40 minutes.Cool off after 3-15 days, do not shake medicine bottle, open medicine bottle cap, get rid of the bottle precipitate at the end.With the fill for the second time of the medicinal liquid behind the sediment exclusion (sterile working) in 500 milliliters vial.Bottleneck is adorned thin film, top cement plug, jewelling lid.Place secondary high-pressure sterilization in the high pressure sterilizer.With greater than 126 ℃ of autoclave sterilizations 40 minutes, be " true man of Xingan soup " herb liquid finished product after the cooling.

" true man of Xingan soup " finished product that the present invention makes is pale brown color medicinal liquid, and transparency is good, deposit-free, the little hardship of mouthfeel.Can in 10 ℃～30 ℃ of room temperature, the antifreeze invariant color in 2 years of keeping in Dark Place, not spoiled, never degenerate, do not lose efficacy.

The Chinese medicine preparation the key technical indexes of " true man of Xingan soup ": containing crude drug 5 grams with every milliliter of medicinal liquid is standard preparation, LD50＞240ml/kg; Every milliliter of medicine contains crude drug 1-10 gram and is effective ratio content; Route of administration has: oral, anus notes, snuffing, fumigation and wash method, be coated with and suffer from the position and all can outward.Consumption and usage: with 60 kg body weight meterings, every milliliter contains crude drug 5 grams and is as the criterion, and morning every day, noon, late each oral 20 milliliters are minimum effective dose.Outer wiping affected part consumption can be at the 10-30 milliliter, and anorectal injects can be at 25 milliliters.The clinical symptoms onset cycle is 1-7 days, and it is 7-15 days that the tumor body suppresses the onset cycle.It is 10-30 minute that microcirculation blood flow improves the onset cycle.

The present invention guarantees drug effect to tumor cancer and pathology position specificity affinity interaction thereof, it gathers, decoct, filter, precipitate staticize, autoclave sterilization, staticize again, precipitate, autoclave sterilization is retention cycle and efficacy stability again manufacturability guarantees.

Claims

1, a kind of processing technology that is used for anti-cancer, controls cancer herb liquid " true man of Xingan soup " is characterized in that:

A) chopping after the Radix Astragali that will gather in special time, Calyx seu fructus physalis, Flos Chrysanthemi Indici, Herba Leonuri, Radix Sanguisorbae, Herba Taraxaci, Flos Inulae dry in the shade, put into aluminum pot or marmite after adding decoction pieces Radix Salviae Miltiorrhizae, Radix Codonopsis, Radix Adenophorae (Radix Glehniae), Radix Ophiopogonis, Herba Hedyotidis Diffusae, Fructus Lycii, Fructus Schisandrae Chinensis, Radix Isatidis, Radix Puerariae, Radix Rubiae, BANJILIAN, Poria, Rhizoma Alismatis, the Radix Paeoniae Alba, Radix Paeoniae Rubra, Radix Rehmanniae Preparata, be added to the above 5cm of medicine layer, the post-heating that stirs boils and boils 30 minutes, filters rapidly with device for drying and filtering; Medicine after the filter is added water to the medicine layer again, boil with the heating of temperature fire and boil 20 minutes after-filtration;

B) will merge rapidly behind the medicinal liquid sediment exclusion of twice decoction, boil with the moderate heat heating and boil 15～20 minutes, cooling was left standstill 6～12 hours, got rid of the visible precipitate thing;

C) medicinal liquid behind the sediment exclusion is stirred evenly fill (need sterile working) in the 500ml vial, bottleneck dress thin film, top cement plug, jewelling lid place in the high pressure sterilizer, with greater than 126 ℃ of high-temperature sterilizations 40 minutes;

(d) cooling of the vial medicinal liquid after will sterilizing is after 3～15 days, avoid shaking medicine bottle and open bottle cap, get rid of the bottle precipitate at the end, medicinal liquid is moved dress, i.e. fill for the second time (sterile working) is in other vial, and bottleneck dress thin film, top cement plug, jewelling lid are put secondary autoclave sterilization in the high pressure sterilizer, still, be finished product " true man of Xingan soup " herb liquid after the cooling with greater than 126 ℃ of high-temperature sterilizations 40 minutes.