CN108785197A - A kind of natural cosmetics preservative composition and preparation method thereof - Google Patents
A kind of natural cosmetics preservative composition and preparation method thereof Download PDFInfo
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- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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Abstract
The present invention relates to a kind of natural cosmetics preservative compositions and preparation method thereof, the natural cosmetics preservative composition is raw material by using 3 kinds of lactobacillus-fermented extract, rice chaff extract and moutan root bark extract natural components and carries out suitable weight proportion so that each raw material component collaboration plays a role；In addition, optimizing the preparation method of the antiseptic composition, specially treated is carried out to the mixing of above-mentioned 3 kinds of raw material components, to improve the anti-corrosion ability of composition and the stability in cosmetics.The antiseptic composition being finally prepared has good cosmetics antisepsis, the experiment proved that can be tested by cosmetics preservation challenge and safely without skin irritatin.
Description
Technical field
The invention belongs to cosmetic technical fields, and in particular to a kind of natural cosmetics preservative composition and its preparation
Method.
Background technology
Contain the more nutriment conducive to microorganism growth, such as carbohydrate, protide in cosmetics.Although in production
If any good environmental Kuznets Curves, it is ensured that product is in germ-free condition, but during the use of consumer, inevitably
The microorganism of ingress of air and skin-derived.If microorganism growth cannot be controlled, the appearance that on the one hand can change product is gentle
Taste, on the other hand, the secondary metabolite of pathogenic microbes also result in various human body harm.
Common pathogenic microorganism includes staphylococcus aureus, Escherichia coli, P. aeruginosa in usual cosmetics
Bacterium, aspergillus niger, Candida albicans etc..In cosmetics, usually inhibit the growth of microorganism by the way that the method for preservative is added,
Nontoxic to human body non-stimulated, chemical property torpescence is also needed simultaneously, is not easy to chemically react with other substances in formula, with
Just stable anti-corrosion ability is kept in 3 years or even longer shelf-life.China exists《Cosmetics safety technical specification》Middle regulation
51 kinds of preservatives that can be used are artificial synthesized preservative, since to skin, there are certain irritations for it, in method
Its limitation used is defined in rule.
Skin problem in recent years caused by the use of Determination of Preservatives in Cosmetics is increasing, and country is for cosmetics
Preservative makes numerous adjustment, such as disabling part parabens, reduces the limitation of iodopropynyl butyl formate, limit
The use scope etc. of methylisothiazolinone processed.Meanwhile consumer also gradually recognizes harm caused by synthetic preservative, and
Start to pursue the cosmetics that preservative free adds.
The ingredient containing there are many in nature with bacteriostasis is commonly used for synthetic preservative replacement.In this respect, it eats
Conduct industry has been carried out a large amount of research, develops many plant extracts with bacteriostasis, source include cumin, tea,
Propolis, Cortex Magnoliae Officinalis, Chinese cassia tree, cloves etc..But such technology is in cosmetics in application, would ordinarily be encountered a variety of difficulties.First, due to
Cosmetics are in compared to the food longer shelf-life, when also facing the use behind repetitious microbial exposure and longer Kaifeng
Between, there is higher requirement to the ability of preservative, therefore, comes to protective system usually using the method for preservation challenge in cosmetics
It is evaluated.Many natural extracts have preferable performance in Bactericidal test, but can not be provided in preservation challenge
Reach the fungistatic effect of standard, practice can not be carried out.Second, the common pathogenic microorganism in food processing, such as it is husky
Door Salmonella, clostridium botulinum etc. is different from the bacterium spectrum of common bacteria in cosmetics, and corresponding preservative selection is also different.Third, not
The substance extracted in natural plants must be just safe, such as the cinnamic acid containing high level in cinnamomum cassia extract, have
Good bactericidal effect, but simultaneously, skin irritatin or even exanthemv are will result under extremely low content.Fourth, various
The effect of containing in plant ingredient is influenced by factors such as season harvest times, and larger difficulty is brought to practical application.Fifth,
The general antimicrobial spectrum of effect ingredient in natural extract is narrow, such as the lactein extracted from lactobacillus fermentation is only
It can inhibit or kill gram-positive bacteria, such as staphylococcus, and to Gram-negative bacteria, such as pseudomonas aeruginosa and large intestine bar
Bacterium, fungi, Candida albicans and aspergillus niger do not act on then.
Invention content
In order to solve the above-mentioned problems in the prior art, the present invention provides a kind of natural cosmetics preservative combination
Object and preparation method thereof.
The technical scheme is that：
A kind of natural cosmetics preservative composition, raw material components include：
Lactobacillus-fermented extract 1-3 parts by weight, rice chaff extract 1-2 parts by weight, moutan root bark extract 0.5-1 weight
Part.
The raw material components of the further preferred natural cosmetics preservative composition include：
Lactobacillus-fermented extract 1.5-2.5 parts by weight, rice chaff extract 1.2-1.8 parts by weight, moutan root bark extract
0.6-0.8 parts by weight.
A method of the natural cosmetics preservative composition is prepared, is included the following steps：
(1) deionized water is added into lactobacillus-fermented extract, adjusts pH, then stirs evenly, obtain suspension S1,
Through centrifuging, detaching, the first clear liquid and the first precipitation are obtained；
(2) rice chaff extract is added into first precipitation, after being diluted with deionized water, stirs evenly, obtains suspended
Liquid S2 obtains the second clear liquid and the second precipitation through centrifuging, detaching；
(3) moutan root bark extract is added into second clear liquid, after mixing to get to the natural change
Cosmetic antiseptic composition.
In step (1), the mass ratio of the deionized water of the addition and the lactobacillus-fermented extract is 2-9:1.
In step (1), pH >=6 are adjusted；The time of the stirring is 10-30min.
In step (1), the rotating speed of the centrifugation is 2500-4000rpm, and the temperature of the centrifugation is 10-15 DEG C, it is described from
The time of the heart is 10-30min.
It is described to be diluted to be diluted to 10-20g in step (2).
In step (2), the time of the stirring is 5-10min.
In step (2), the rotating speed of the centrifugation is 2500-4000rpm, and the temperature of the centrifugation is 10-15 DEG C, it is described from
The time of the heart is 10-30min.
Application of the antiseptic composition in cosmetics.
To facilitate the understanding of the present invention, now in the present invention bulk pharmaceutical chemicals and drug effect be further elaborated.
Lactobacillus-fermented extract：Containing there are many antibacterial peptides, especially lactein, it is made of 34 amino acid residues,
For white or the crystalline powder or particle of yellowish, usual commercial product is the powder using sodium chloride as decentralized medium.Breast
Sour rhzomorph inhibits the biosynthesis of peptide glycan in cell wall to cause cell content to make cytoplasma membrane and phosphoric acid biosynthesis block
Object and atriphos leak, and finally cause cell cracking.
Rice chaff extract：Containing phytic acid, there is stronger chelation to metal ion, stabilizing lactic acid bacteria can be helped plain,
And enhance its anti-corrosion ability.
Moutan root bark extract：Containing Paeonol, commonly used in analgesia, anti-inflammatory, antipyretic and inhibition allergy, by changing
Become membrane passage, there is certain inhibiting effect to all kinds of fungies.
Beneficial effects of the present invention are：
A kind of natural cosmetics preservative composition of the present invention, by using lactobacillus-fermented extract, rice
3 kinds of natural components of chaff extract and moutan root bark extract are raw material and carry out suitable weight proportion so that each raw material component
Collaboration plays a role, wherein the lactein in lactobacillus-fermented extract can inhibit or kill gram-positive bacteria, rice chaff
Extract can help stabilizing lactic acid bacteria plain, and enhance its anti-corrosion ability, and the Paeonol in moutan root bark extract is to all kinds of true
Bacterium has certain inhibiting effect；In addition, the preparation method of the antiseptic composition is optimized, to above-mentioned 3 kinds of raw material components
Mixing carried out specially treated, to improve the anti-corrosion ability of composition and the stability in cosmetics.Final system
Standby obtained antiseptic composition, has good cosmetics antisepsis, the experiment proved that can be chosen by cosmetics anti-corrosion
War is tested and safety is without skin irritatin.
Specific implementation mode
Below by specific embodiment, the invention will be further described.
Embodiment 1
The present embodiment provides a kind of natural cosmetics preservative composition, raw material components include：
Lactobacillus-fermented extract 1g, rice chaff extract 1g, moutan root bark extract 0.5g.
Further, a kind of method preparing the natural cosmetics preservative composition is provided, is included the following steps：
(1) 9g deionized waters are added into lactobacillus-fermented extract, it is 6 to adjust pH, then stirs 10min, obtains palm fibre
Color suspension S1, under the conditions of 10 DEG C, after 2500rpm centrifuges 30min, separation obtains light yellow first clear liquid and brown the
One precipitation；
(2) rice chaff extract is added in being precipitated to the brown first, is diluted to 10g with deionized water, stirs 5min, obtain
To brown suspension S2, under the conditions of 10 DEG C, after 2500rpm centrifuges 30min, separation obtains the second clear liquid of brown and brown
Second precipitation；
(3) moutan root bark extract is added into the second clear liquid of the brown, after mixing to get to described natural
Cosmetics preservative composition.
Embodiment 2
The present embodiment provides a kind of natural cosmetics preservative composition, raw material components include：
Lactobacillus-fermented extract 3g, rice chaff extract 2g, moutan root bark extract 1g.
Further, a kind of method preparing the natural cosmetics preservative composition is provided, is included the following steps：
(1) 7g deionized waters are added into lactobacillus-fermented extract, it is 6.5 to adjust pH, then stirs 30min, obtains
Brown suspension S1, under the conditions of 15 DEG C, after 4000rpm centrifuges 10min, separation obtains light yellow first clear liquid and brown
First precipitation；
(2) rice chaff extract is added in being precipitated to the brown first, is diluted to 20g with deionized water, stirs 10min,
Brown suspension S2 is obtained, under the conditions of 15 DEG C, after 4000rpm centrifuges 10min, separation obtains the second clear liquid of brown and palm fibre
Color second precipitates；
(3) moutan root bark extract is added into the second clear liquid of the brown, after mixing to get to described natural
Cosmetics preservative composition.
Embodiment 3
The present embodiment provides a kind of natural cosmetics preservative composition, raw material components include：
Lactobacillus-fermented extract 1.5g, rice chaff extract 1.2g, moutan root bark extract 0.6g.
Further, a kind of method preparing the natural cosmetics preservative composition is provided, is included the following steps：
(1) 8.5g deionized waters are added into lactobacillus-fermented extract, it is 6.8 to adjust pH, then stirs 15min, obtains
To brown suspension S1, under the conditions of 12 DEG C, after 3000rpm centrifuges 20min, separation obtains light yellow first clear liquid and palm fibre
Color first precipitates；
(2) rice chaff extract is added in being precipitated to the brown first, is diluted to 10g with deionized water, stirs 6min, obtain
To brown suspension S2, under the conditions of 12 DEG C, after 3000rpm centrifuges 20min, separation obtains the second clear liquid of brown and brown
Second precipitation；
(3) moutan root bark extract is added into the second clear liquid of the brown, after mixing to get to described natural
Cosmetics preservative composition.
Embodiment 4
The present embodiment provides a kind of natural cosmetics preservative composition, raw material components include：
Lactobacillus-fermented extract 2.5g, rice chaff extract 1.8g, moutan root bark extract 0.8g.
Further, a kind of method preparing the natural cosmetics preservative composition is provided, is included the following steps：
(1) 7.5g deionized waters are added into lactobacillus-fermented extract, it is 7.2 to adjust pH, then stirs 25min, obtains
To brown suspension S1, under the conditions of 15 DEG C, after 3500rpm centrifuges 15min, separation obtains light yellow first clear liquid and palm fibre
Color first precipitates；
(2) rice chaff extract is added in being precipitated to the brown first, is diluted to 10g with deionized water, stirs 8min, obtain
To brown suspension S2, under the conditions of 15 DEG C, after 3500rpm centrifuges 15min, separation obtains the second clear liquid of brown and brown
Second precipitation；
(3) moutan root bark extract is added into the second clear liquid of the brown, after mixing to get to described natural
Cosmetics preservative composition.
Embodiment 5
The present embodiment provides a kind of natural cosmetics preservative composition, raw material components include：
Lactobacillus-fermented extract 2g, rice chaff extract 1.5g, moutan root bark extract 0.7g.
Further, a kind of method preparing the natural cosmetics preservative composition is provided, is included the following steps：
(1) 8g deionized waters are added into lactobacillus-fermented extract, it is 7.2 to adjust pH, then stirs 20min, obtains
Brown suspension S1, under the conditions of 10 DEG C, after 3000rpm centrifuges 30min, separation obtains light yellow first clear liquid and brown
First precipitation；
(2) rice chaff extract is added in being precipitated to the brown first, is diluted to 10g with deionized water, stirs 5min, obtain
To brown suspension S2, under the conditions of 10 DEG C, after 3000rpm centrifuges 30min, separation obtains the second clear liquid of brown and brown
Second precipitation；
(3) moutan root bark extract is added into the second clear liquid of the brown, after mixing to get to described natural
Cosmetics preservative composition.
Experimental example
One, antibacterial effect is tested
1, antibacterial effect test sample (unit is prepared with preparation method in the following proportions：g)
| Lactobacillus-fermented extract | Rice chaff extract | Moutan root bark extract | |
| Blank | |||
| Sample A | 1 | ||
| Sample B | 1 | 1 | |
| Sample C | 1 | 1 | |
| Sample D | 3 | 1 | |
| Sample E | 3 | 1 | 0.5 |
Preparation method is as follows：
Sample A：9g deionized waters are added into lactobacillus-fermented extract, stir evenly to obtain the final product；
Sample B：8g deionized waters are added into lactobacillus-fermented extract and rice chaff extract, stir evenly to obtain the final product；
Sample C：9g deionized waters are added into lactobacillus-fermented extract, after stirring evenly, adjust pH >=6, stirring
20min obtains suspension S1, through centrifuging, detaching, obtains the first clear liquid and the first precipitation；Rice is added into first precipitation
Chaff extract is diluted to 10g with deionized water, stirs evenly, and obtains suspension S2, through centrifuging, detach, obtain the second clear liquid and
Second precipitation；Take the second clear liquid to obtain the final product；
Sample D：7g deionized waters are added into lactobacillus-fermented extract, after stirring evenly, adjust pH >=6, stirring
20min obtains suspension S1, through centrifuging, detaching, obtains the first clear liquid and the first precipitation；Rice is added into first precipitation
Chaff extract is diluted to 10g with deionized water, stirs evenly, and obtains suspension S2, through centrifuging, detach, obtain the second clear liquid and
Second precipitation；Take the second clear liquid to obtain the final product；
Sample E：7g deionized waters are added into lactobacillus-fermented extract, after stirring evenly, adjust pH >=6, stirring
20min obtains suspension S1, through centrifuging, detaching, obtains the first clear liquid and the first precipitation；Rice is added into first precipitation
Chaff extract is diluted to 10g with deionized water, stirs evenly, and obtains suspension S2, through centrifuging, detach, obtain the second clear liquid and
Second precipitation；Moutan root bark extract is added into the second clear liquid, after stirring evenly to obtain the final product.
2, antibacterial effect is tested
Blank (unit：logCFU/g)
| 0 day | 1 day | 7 days | 14 days | 21 days | 28 days | |
| Staphylococcus aureus | 6.2 | 6.5 | 6.4 | 6.6 | 6.8 | 6.9 |
| Pseudomonas aeruginosa | 6.2 | 6.5 | 6.3 | 6.6 | 6.8 | 7.0 |
| Escherichia coli | 6.2 | 6.2 | 6.2 | 6.4 | 6.6 | 6.5 |
| Candida albicans | 5.3 | 5.7 | 6.2 | 6.6 | 7.0 | 7.5 |
| Aspergillus niger | 5.5 | 5 | 4.5 | 4.2 | 3.9 | 4.0 |
Sample A (units：logCFU/g)
| 0 day | 1 day | 7 days | 14 days | 21 days | 28 days | |
| Staphylococcus aureus | 6.2 | <0 | <0 | <0 | <0 | <0 |
| Pseudomonas aeruginosa | 6.2 | 5.8 | 6.0 | 6.0 | 6.1 | 6.0 |
| Escherichia coli | 6.2 | 6.2 | 6.2 | 6.3 | 6.2 | 6.2 |
| Candida albicans | 5.4 | 5.5 | 5.4 | 5.4 | 5.3 | 5.3 |
| Aspergillus niger | 5.4 | 5 | 4.5 | 4.2 | 3.9 | 4.0 |
Sample B (units：logCFU/g)
| 0 day | 1 day | 7 days | 14 days | 21 days | 28 days | |
| Staphylococcus aureus | 6.2 | <0 | <0 | <0 | <0 | <0 |
| Pseudomonas aeruginosa | 6.2 | 5.3 | 5.2 | 4.8 | 4.2 | 4.2 |
| Escherichia coli | 6.2 | 5.0 | 4.2 | 2.2 | 2.0 | 2.0 |
| Candida albicans | 5.4 | 4.8 | 4.2 | 3.4 | 3.3 | 3.3 |
| Aspergillus niger | 5.4 | 5 | 4.5 | 4.0 | 3.9 | 3.8 |
Sample C (units：logCFU/g)
| 0 day | 1 day | 7 days | 14 days | 21 days | 28 days | |
| Staphylococcus aureus | 6.2 | <0 | <0 | <0 | <0 | <0 |
| Pseudomonas aeruginosa | 6.2 | 4.8 | 4.2 | 3.8 | 3.8 | 3.8 |
| Escherichia coli | 6.2 | 5.0 | 4.2 | 2.2 | <0 | <0 |
| Candida albicans | 5.4 | 4.8 | 4.2 | 2.4 | <0 | <0 |
| Aspergillus niger | 5.4 | 5 | 4.5 | 4.0 | 3.9 | 3.8 |
Sample D (units：logCFU/g)
| 0 day | 1 day | 7 days | 14 days | 21 days | 28 days | |
| Staphylococcus aureus | 6.2 | <0 | <0 | <0 | <0 | <0 |
| Pseudomonas aeruginosa | 6.2 | 4.8 | 4.0 | 3.2 | 2.2 | 2.2 |
| Escherichia coli | 6.2 | 4.5 | 3.0 | <0 | <0 | <0 |
| Candida albicans | 5.4 | 4.2 | 3.5 | 2.0 | <0 | <0 |
| Aspergillus niger | 5.4 | 5 | 4.5 | 4.0 | 3.9 | 3.8 |
Sample E (units：logCFU/g)
| 0 day | 1 day | 7 days | 14 days | 21 days | 28 days | |
| Staphylococcus aureus | 6.2 | <0 | <0 | <0 | <0 | <0 |
| Pseudomonas aeruginosa | 6.2 | 4.6 | 2.0 | <0 | <0 | <0 |
| Escherichia coli | 6.2 | 4.0 | 2.2 | <0 | <0 | <0 |
| Candida albicans | 5.4 | 3.8 | 2.0 | <0 | <0 | <0 |
| Aspergillus niger | 5.4 | 4.5 | 4.0 | 2.2 | <0 | <0 |
Conclusion
Single lactobacillus-fermented extract can only inhibit gram-positive bacteria；Rice chaff extract, which is added, can enhance anti-corrosion
Ability；Preparation method after present invention optimization can enhance the anti-corrosion ability of system；Further increase lactobacillus-fermented extract
Content it is little to mould and Gram-negative bacteria effect；Moutan root bark extract is added, composition can be enhanced to mould
Rejection ability.
Two, cosmetics preservation challenge
1, antiseptic composition (unit：g)
| Lactobacillus-fermented extract | Rice chaff extract | Moutan root bark extract | |
| Sample F | 1 | 1 | 0.5 |
| Sample G | 2 | 1 | 0.7 |
| Sample H | 3 | 2 | 1 |
| Sample I | 1 | 1 | 0.5 |
Preparation method is as follows：
Sample F：9g deionized waters are added into lactobacillus-fermented extract, after stirring evenly, adjust pH >=6, stirring
20min obtains suspension S1, through centrifuging, detaching, obtains the first clear liquid and the first precipitation；Rice is added into first precipitation
Chaff extract is diluted to 10g with deionized water, stirs evenly, and obtains suspension S2, through centrifuging, detach, obtain the second clear liquid and
Second precipitation；Moutan root bark extract is added into the second clear liquid, after stirring evenly to obtain the final product；
Sample G：8g deionized waters are added into lactobacillus-fermented extract, after stirring evenly, adjust pH >=6, stirring
20min obtains suspension S1, through centrifuging, detaching, obtains the first clear liquid and the first precipitation；Rice is added into first precipitation
Chaff extract is diluted to 10g with deionized water, stirs evenly, and obtains suspension S2, through centrifuging, detach, obtain the second clear liquid and
Second precipitation；Moutan root bark extract is added into the second clear liquid, after stirring evenly to obtain the final product；
Sample H：7g deionized waters are added into lactobacillus-fermented extract, after stirring evenly, adjust pH >=6, stirring
20min obtains suspension S1, through centrifuging, detaching, obtains the first clear liquid and the first precipitation；Rice is added into first precipitation
Chaff extract is diluted to 10g with deionized water, stirs evenly, and obtains suspension S2, through centrifuging, detach, obtain the second clear liquid and
Second precipitation；Moutan root bark extract is added into the second clear liquid, after stirring evenly to obtain the final product；
Sample I：Lactobacillus-fermented extract, rice chaff extract and moutan root bark extract are mixed, stirred evenly to obtain the final product；
2, cosmetic formulations
(1) water aqua type cosmetics (unit：g)
| Composition | Formula 1 | Formula 2 | Formula 3 | Formula 7 |
| Water | To 1000 | To 1000 | To 1000 | To 1000 |
| Glycerine | 50 | 50 | 50 | 50 |
| Hyaluronic acid | 1 | 1 | 1 | 1 |
| Trehalose | 5 | 5 | 5 | 5 |
| Antiseptic composition | Sample F | Sample G | Sample H | Sample I |
(2) emulsion-type cosmetics (unit：g)
| Composition | Formula 4 | Formula 5 | Formula 6 |
| Water | To 1000 | To 1000 | To 1000 |
| Sunflower seed oil | 150 | 150 | 150 |
| Marine algae extract | 8 | 8 | 8 |
| Lecithin | 30 | 30 | 30 |
| Antiseptic composition | Sample F | Sample G | Sample H |
3, cosmetics preservation challenge, stability and safety
Conclusion：
It is cotton-shaped applied to will appear in cosmetics without antiseptic composition prepared by the preparation method that the present invention optimizes
Precipitate；Since the solubility of moutan root bark extract in water is limited, when too high levels, the cosmetics of water aqua type are in low temperature
When will appear precipitation phenomenon, and being applied to emulsion-type cosmetics, since part can be dissolved in grease, its anti-corrosion ability is influenced,
But also therefore, high-content is not in low temperature precipitation phenomenon.
The above description is merely a specific embodiment, but scope of protection of the present invention is not limited thereto, any
Those familiar with the art in the technical scope disclosed by the present invention, can easily think of the change or the replacement, and should all contain
Lid is within protection scope of the present invention.Therefore, protection scope of the present invention should be based on the protection scope of the described claims.
Claims (10)
1. a kind of natural cosmetics preservative composition, which is characterized in that raw material components include：
Lactobacillus-fermented extract 1-3 parts by weight, rice chaff extract 1-2 parts by weight, moutan root bark extract 0.5-1 parts by weight.
2. natural cosmetics preservative composition according to claim 1, which is characterized in that raw material components include：
Lactobacillus-fermented extract 1.5-2.5 parts by weight, rice chaff extract 1.2-1.8 parts by weight, moutan root bark extract 0.6-
0.8 parts by weight.
3. a kind of method preparing natural cosmetics preservative composition as claimed in claim 1 or 2, which is characterized in that packet
Include following steps：
(1) be added deionized water into lactobacillus-fermented extract, adjust pH, then stir evenly, obtain suspension S1, through from
The heart, separation obtain the first clear liquid and the first precipitation；
(2) rice chaff extract is added into first precipitation, after being diluted with deionized water, stirs evenly, obtains suspension S2,
Through centrifuging, detaching, the second clear liquid and the second precipitation are obtained；
(3) moutan root bark extract is added into second clear liquid, after mixing to get to the natural cosmetics
Antiseptic composition.
4. the method according to claim 3 for preparing natural cosmetics preservative composition, which is characterized in that step
(1) in, the mass ratio of the deionized water of the addition and the lactobacillus-fermented extract is 2-9:1.
5. the method according to claim 3 for preparing natural cosmetics preservative composition, which is characterized in that step
(1) in, pH >=6 are adjusted；The time of the stirring is 10-30min.
6. the method according to claim 3 for preparing natural cosmetics preservative composition, which is characterized in that step
(1) in, the rotating speed of the centrifugation is 2500-4000rpm, and the temperature of the centrifugation is 10-15 DEG C, and the time of the centrifugation is
10-30min。
7. the method according to claim 3 for preparing natural cosmetics preservative composition, which is characterized in that step
(2) described to be diluted to be diluted to 10-20g in.
8. the method according to claim 3 for preparing natural cosmetics preservative composition, which is characterized in that step
(2) in, the time of the stirring is 5-10min.
9. the method according to claim 3 for preparing natural cosmetics preservative composition, which is characterized in that step
(2) in, the rotating speed of the centrifugation is 2500-4000rpm, and the temperature of the centrifugation is 10-15 DEG C, and the time of the centrifugation is
10-30min。
10. application of any one of the claim 1-9 antiseptic compositions in cosmetics.
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| CN110200899A (en) * | 2019-07-05 | 2019-09-06 | 欧诗漫生物股份有限公司 | A kind of preservative and its preparation method and application |
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