CN108778396A - It is close to the micro-needle roller device of the viscoplasticity connection cover of structure including bottleneck lower end - Google Patents

It is close to the micro-needle roller device of the viscoplasticity connection cover of structure including bottleneck lower end Download PDF

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Publication number
CN108778396A
CN108778396A CN201780016670.4A CN201780016670A CN108778396A CN 108778396 A CN108778396 A CN 108778396A CN 201780016670 A CN201780016670 A CN 201780016670A CN 108778396 A CN108778396 A CN 108778396A
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CN
China
Prior art keywords
idler wheel
bottleneck
medicine bottle
viscoplasticity
connection cover
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Granted
Application number
CN201780016670.4A
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Chinese (zh)
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CN108778396B (en
Inventor
李昌雨
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Yi Chang Woo
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Yi Chang Woo
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0023Drug applicators using microneedles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0061Methods for using microneedles

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Dermatology (AREA)
  • Medical Informatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)

Abstract

The invention discloses a kind of micro-needle roller devices, can discretely be incorporated in medicine bottle, and the medicine bottle stores liquid medicine, and includes the bottleneck with certain internal diameter.The micro-needle roller device includes:Viscoplasticity connection cover covers the bottleneck upper end opening portion, and can discretely be incorporated in the medicine bottle;Idler wheel guide clamp is incorporated in viscoplasticity connection cover upper end;Micropin idler wheel is oriented to fixture in the idler wheel and maintains linear movement;And drug delivery mechanism, the micropin pair of rollers skin under pressure, by the drug delivery in the medicine bottle to the faller gill of the micropin idler wheel, wherein when the viscoplasticity connection cover is incorporated in the medicine bottle upper end, including:Lower part outer cylindrical portion is tightly attached to the bottleneck peripheral surface;Lower tub portion is inserted in the medicine bottle opening portion, is tightly attached to the bottleneck inner peripheral surface;Plate ring portion, connect the lower part outer cylindrical portion upper end Inner weeks and the lower tub portion upper end periphery while, be tightly attached to the bottleneck upper end, and the lower end of lower end and the bottleneck of the lower tub portion Jing Guo the lower part outer cylindrical portion, more extend downwards.

Description

It is close to the micro-needle roller device of the viscoplasticity connection cover of structure including bottleneck lower end
Technical field
Micropin idler wheel is utilized the present invention relates to a kind of, forms subtle pin hole on the skin, injects medicine by these pin holes The micro-needle roller device of object, in more detail, be related in the state of being connect with micropin idler wheel contact medicine bottle when, not only with the bottle of medicine bottle Neck upper end, and the micro-needle roller device with viscoplasticity connection cover being all close to bottleneck lower end and inside bottle neck face.
Background technology
It is just suggested before micro-needle roller device.These existing needle roller devices are formed in medicine bottle upper end including covering and open The component of oral area, and this component has the cutting section of elastically deformable.Therefore, when medicine bottle is reversed, by pre- near cutting section If ball weight, cutting section be extruded so that opening portion only opened to a direction.But this needle roller devices use medicine Object falls the transmission mode in faller gill farther out, it is difficult to each needle transmission with reliability drug, and not only be difficult control by The cutting section of ball weight deforms, and with the increase of service life, and cutting section permanent deformation can become the shape that cannot be reused State.
In particular, existing technology has inconvenience more on combining micropin idler wheel and medicine bottle.In addition, the shortcomings that existing apparatus, exists Bolt locking or engagement etc. are needed in the assembling of the assembly including micropin idler wheel, therefore assemblability is poor.
In this regard, the present inventor proposes a kind of micro-needle roller device, separably contacted by viscoplasticity connection cover Medicine bottle, the micro-needle roller device include the inside bottle neck for being partly embedded in medicine bottle and the lower tub portion be close to and are tightly attached to Lower part outer cylindrical portion outside the bottleneck of medicine bottle, and contacted in medicine bottle by dual structure, wherein the medicine bottle has in bottleneck upper end Opening portion.
Invention content
(project to be solved)
Inventor hereof has previously proposed micro-needle roller device, in the lower part outer cylindrical portion lower end of viscoplasticity connection cover, including bullet Property it is stuck in the hook portion of the bottleneck upper end sill of medicine bottle.However, so viscoplasticity connection cover, its underpart inner cylinder portion are only inserted Among the bottleneck of medicine bottle, therefore, there is also being incorporated in medicine bottle with being unable to more stable and stronger, and pass through lower tub portion and bottleneck inner face Between subtle gap, the worry that drug is leaked.
Therefore, project to be solved by this invention is to provide a kind of micro-needle roller device, and micropin idler wheel is contacted in medicine bottle The lower tub portion of viscoplasticity connection cover extend to inside bottle neck lower end, can also be tightly attached to inside bottle neck lower end, and then not only Ensure it is more stable, firmly contact in viscoplasticity connection cover, also can tighter prevent undesirable drug from revealing.
(the method to solve the problem)
A side according to the present invention, medicine bottle can be discretely incorporated in by providing, and the medicine bottle stores liquid medicine, and It include the micro-needle roller device of the bottleneck with certain internal diameter.The micro-needle roller device includes:Viscoplasticity connection cover covers institute Bottleneck upper end opening portion is stated, and can discretely be incorporated in the medicine bottle;Idler wheel guide clamp is incorporated in the viscoplasticity connection Cover end;Micropin idler wheel is oriented to fixture in the idler wheel and maintains linear movement;And drug delivery mechanism, the micropin pair of rollers Skin under pressure, by the drug delivery in the medicine bottle to the faller gill of the micropin idler wheel, wherein viscoplasticity connection When lid is incorporated in the medicine bottle upper end, including:Lower part outer cylindrical portion is tightly attached to the bottleneck peripheral surface;Lower tub portion, is inserted in In the medicine bottle opening portion, it is tightly attached to the bottleneck inner peripheral surface;Plate ring portion, connect the lower part outer cylindrical portion upper end Inner weeks and While the upper end periphery in the lower tub portion, it is tightly attached to the bottleneck upper end, and the lower tub portion is by under described The lower end of the lower end of portion's outer cylindrical portion and the bottleneck more extends downwards.
According to one embodiment, the lower tub portion has the annular protrusion protruded to radial direction, institute in lower end When stating viscoplasticity connection cover and being incorporated in the medicine bottle, the annular protrusion by the inside bottle neck and contraction distortion it Afterwards, it with reinstatement, hangs over the enlarged portion under the bottleneck lower end of the bottleneck and is close to.
According to one embodiment, the viscoplasticity connection cover includes:Top outer cylindrical portion is tightly attached to the idler wheel guide clamp Lower end sill lateral surface;Upper inner cylinder portion has concentric shafts with the top outer cylindrical portion, and is formed in the top outer cylindrical portion Side;Annular maintains lid, extends on the inside of top outer cylindrical portion upper end, and the annular maintains lid by the idler wheel guide clamp Lower end sill be embedded in inwardly, while so as to flexible deformation, the lower end sill are tightly attached to the lower end in the state of insertion The upper side of sill is fixed on the viscoplasticity connection cover by seal the state of the idler wheel guide clamp.
According to one embodiment, the viscoplasticity connection cover is integrally included in the hollow inner side shape in the upper inner cylinder portion At the valve film of valve opening, the micropin idler wheel includes:Rolling wheel support, according to the guiding groove for being formed in the idler wheel guide clamp, if It is set to linear movement up and down;Core rotary shaft is arranged to rotate the rolling wheel support;Idler wheel spool, to the core Rotary shaft is rotatably arranged;Multiple annular faller gills, rotate the core rotary shaft together with the idler wheel spool, and institute It includes valve operation portion to state drug delivery mechanism, pulls together to transmit drug from the medicine bottle to the faller gill side with the valve film, described Valve operation portion includes:Bar portion, with the seamless state for being embedded in the valve opening and the micropin idler wheel integrally linear movement up and down; Tapered pressurization part is formed in the centre of the bar portion, from lower end of the bar portion with same diameter to than the bar The upper end of portion's major diameter, diameter gradually increase;Drug is formed in the tapered pressurization part by splitted groove, and it is described tapered plus When the splenium pressurization valve film, the valve film is squeezed by the tapered pressurization part, and then expands the valve opening, and the valve opening In the state of being expanded by the tapered pressurization part, it connect and is opened by splitted groove with the drug.
(invention effect)
Micro-needle roller device according to the present invention, the advantage is that, the viscoplasticity by the contact of micropin idler wheel in medicine bottle connects The lower tub portion of lid extends to inside bottle neck lower end, can also be tightly attached to inside bottle neck lower end, and then not only ensures more stable, hard Admittedly contact in viscoplasticity connection cover, also can tighter prevent undesirable drug from revealing.
Other advantages and effect of the present invention, understand by the following description of the embodiments.
Description of the drawings
Fig. 1 is the front elevation for showing to be incorporated in the micro-needle roller device of medicine bottle according to one embodiment of present invention.
Fig. 2 is the decomposition amplification profile diagram for showing micro-needle roller device according to an embodiment of the invention.
Fig. 3 is the decomposition profile diagram for showing micro-needle roller device according to an embodiment of the invention.
Fig. 4 is the stereogram for showing micropin idler wheel.
Fig. 5 is the exploded perspective view for showing micropin idler wheel.
Fig. 6 is the view for showing the drug delivery mechanism for illustrating micro-needle roller device and acting on.
Specific implementation mode
Hereinafter, the preferred embodiment of the present invention is described in detail with reference to accompanying drawings.Attached drawing and this explanation is to help Those skilled in the art's the understanding of the present invention and provide.Therefore, these figures and explanation cannot be explained as being to limit this hair Bright range.
As shown in Figure 1 to Figure 3, micro-needle roller device 1 according to an embodiment of the invention is incorporated in receiving liquid The upper end of the medicine bottle 2 of drug and utilize.The medicine bottle 2 is included in upper end and has opening portion, and the vertical-type with certain internal diameter Bottleneck 2b.The annular sill 2a protruded to radial lateral direction, the inside of the bottleneck 2b are formed in the upper end of the bottleneck 2b Lower end forms the enlarged portion 2c of the internal diameter bigger than the bottleneck 2b.The enlarged portion 2c connects inner face and the institute of the bottleneck 2b State the body interior of medicine bottle 2.
In addition, the micro-needle roller device 1 includes:Viscoplasticity connection cover 12 covers the upper end opening portion of the medicine bottle 2, And it is incorporated in the medicine bottle;Idler wheel guide clamp 14 is incorporated in 12 upper end of viscoplasticity connection cover;Micropin idler wheel 20, can be The idler wheel is oriented to fixture 14 and maintains to move linearly up and down;And drug delivery mechanism, the micropin idler wheel 20 add skin When pressure, by the drug delivery in the medicine bottle 2 to the faller gill 26 of the micropin idler wheel 20.
In addition, the micro-needle roller device 1 may also include connection ring 13, draw for viscoplasticity connection cover 12 and the idler wheel Lead the assembling of the more reliability between fixture 14.
In the present embodiment, the medicine bottle 2 is as common medicine bottle shape store drug.The drug can be contributed in skin Skin wears a variety of drugs of the acupuncture therapy of multiple fine holes.As described above, the medicine bottle 2 the upper ends bottleneck 2b opening portion it is outer Circumferential surface has the annular sill 2a protruded to radial direction, while forming enlarged portion 2c on the downside of the lower end of bottleneck 2b.
A part of the viscoplasticity connection cover 12 as micro-needle roller device 1, can be assembled by sealing state, to micropin Roller devices 1 have reliability to medicine bottle 2.In addition, the viscoplasticity connection cover 12 can divide the medicine bottle 2 in a manner of a key While liftoff combination, idler wheel guide clamp 14 is also separably combined.
The assemblability with the assemblability of medicine bottle 2 and with idler wheel guide clamp 14 can be improved in the viscoplasticity connection cover 12, by The silicon materials of the viscoelastic material of the elastic dilatation that valve opening can be improved and shrinkage described further below are formed.In addition, institute When stating viscoplasticity connection cover 12 and being incorporated in the upper end of the medicine bottle 2, including it is tightly attached to the tool of the bottleneck 2b peripheral surfaces of the medicine bottle 2 There is the lower part outer cylindrical portion 120a of circular inner periphery;It is inserted in 2 opening portion of the medicine bottle, is tightly attached in the bottleneck 2b of the medicine bottle 2 The lower tub portion 120b with circular circumference of circumferential surface;Connect upper end Inner weeks of the lower part outer cylindrical portion 120a and the lower part While the upper end periphery of inner cylinder portion 120b, it is tightly attached to the plate ring portion 120c of the upper ends the bottleneck 2b;It is incorporated in the idler wheel When the lower end of guide clamp 14, it is tightly attached to the top outer cylindrical portion 121 of 140 lateral surface of lower end sill of the idler wheel guide clamp 14; There are concentric shafts with the top outer cylindrical portion 121, and be formed in the upper inner cylinder portion 122 of 121 inside of the top outer cylindrical portion.
According to the present embodiment, the lower tub portion 120b and the lower part outer cylindrical portion 120a have identical upper end level, And the downward extension that the lower tub portion 120b is longer than the lower part outer cylindrical portion 120a.In particular, the lower tub portion 120b extends downwards by the lower end of the bottleneck 2b, is tightly attached under the lower ends the bottleneck 2b and the lower ends the bottleneck 2b The enlarged portion 2c of side.The lower tub portion 120b has the annular protrusion 129 protruded to radial direction in lower end.By viscoelastic Property connection cover 12 when being incorporated in medicine bottle 2, the annular relief 129 passes through inside the bottleneck 2b of the medicine bottle 2 and shrinks change After shape, complete to be inserted into, then together with recovery, the expansion for covering the lower end of the bottleneck 2b and being stuck on the downside of the lower ends the bottleneck 2b It is strongly tightly attached to the enlarged portion 2c while opening portion 2c.
The viscoplasticity combined with the idler wheel guide clamp 14 for the micropin idler wheel 20 that can maintain to move linearly up and down is connected When lid 12 is incorporated in the upper end of medicine bottle 2, it is formed in the annular protrusion 129 of 12 lower tub portion 120b of the viscoplasticity connection cover After being inserted into the bottleneck 2b and flexibly shrinking, restore by the lower ends the bottleneck 2b and again to original state.The ring When shape protrusion 129 is restored to original state, have via the annular protrusion 129 outer than the bottleneck 2b internal diameter biggers Diameter, the viscoplasticity connection cover 12 are firmly fixed on medicine bottle 2.
In addition, the viscoplasticity connection cover 12 includes that extended annular maintains inwardly from the front end of the outer cylindrical portion 121 121a is covered, the annular maintains lid 121a to have viscoplasticity as a part for the viscoplasticity connection cover 12, and makes described The lower end sill 140 of idler wheel guide clamp 14 are embedded while be elastically deformed inwardly, in the shape that the lower end sill 140 are embedded into Under state, it is tightly attached to the upper side of the lower end sill 140, the idler wheel guide clamp 14 is firmly fixed in a sealed state The viscoplasticity connection cover 12.
In addition, the viscoplasticity connection cover 12 integrally comprises, it is integrally formed on the inside of the mesoporous in upper inner cylinder portion 122 Valve film 123.The valve film 123 has valve opening 1232 in center, allows by viscoplasticity material, especially valve described in the characteristic of silicon material Hole 1232 is flexibly expanded or is shunk by external force.The valve film 123 and have in micropin idler wheel 20 that the valve opening 1232 is formed Valve operation portion 23 together, constitute a drug delivery mechanism, but before valve operation portion 23 is with the micropin idler wheel 20 Into and retreat and interact with the valve film 123, and then play the role of the opening and closing valve opening 1232.
The lower tub portion 120b of the viscoplasticity connection cover 12 is close to be inserted into the bottleneck of the medicine bottle 2 with entire periphery 2b is internally formed.Also, the lower tub portion 120b is extended for than the bottleneck 2b longer lengths, in the bottle Strongly it is close to the bottleneck 2b lower end side enlarged portions 2c on the downside of the lower ends neck 2b.
Therefore, when the viscoplasticity connection cover 12 is incorporated in the medicine bottle 2, the lower tub portion 120b is fully close to In the entire inner peripheral surfaces of bottleneck 2b of the medicine bottle 2, the sealing function for preventing drug from revealing is played.
As shown in Figures 3 to 5, the idler wheel guide clamp 14 is columnar structured as the mesoporous of top and lower open, In the state that the micropin idler wheel 20 is on the inside of itself mesoporous, can maintain the micropin idler wheel 20 advance up and down or after It moves back.The idler wheel guide clamp 14 has what about the 20 guiding micropin idler wheel in the face of facing each other moved along a straight line in inner peripheral surface A pair of of guiding groove 142.The idler wheel guide clamp 14 has to prevent the micropin idler wheel in the front end of the guiding groove 142 20 disengaging and the upper end stop 143 formed.
In addition, the micropin idler wheel 20 can maintain to move along a straight line up and down as in the idler wheel guide clamp 14, including:Rolling Wheel support 22 is arranged to be moved linearly up and down according to the guiding groove 142;Core rotary shaft 21 is arranged to the idler wheel Holder 22 can be rotated;Idler wheel spool 24 is arranged to that the core rotary shaft 21 can be rotated;Multiple annular faller gills 26 And multiple annular gaskets 28, the idler wheel spool 24 is all constrained in the idler wheel spool 24 together to the core rotary shaft 21 It is rotated.
The idler wheel spool 24 includes:Mesoporous rotary shaft 241 is arranged to that the core rotary shaft 21 can be rotated, And it can be rotated in the peripheral surface of the core rotary shaft 21;A pair of of spool cap 242a, 242b, configuration are rotated in the mesoporous The both ends of axis 241 include that faller gill-gasket group of the multiple annular faller gill 26 and multiple annular gaskets 28 falls off to prevent. At this moment, at least one spool cap 242b can make the assembling of annular faller gill 26 and annular gasket 28 in a pair of of spool cap 242a, 242b, It is further convenient for detaching, the mesoporous rotary shaft 241 is separably assembled.
Even if as described above, by about if multiple annular faller gills 26 and multiple annular gaskets 28 assembled with the state of separation Beam all can integrally be rotated in the mesoporous rotary shaft 241.As the constraint annular faller gill 26 and air ring The means of piece 26, including:Keyway 2412 is alongst formed in the peripheral surface of the mesoporous rotary shaft 241;First key 265, it is formed in each inner peripheral surface of the faller gill 26;And second key 285, it is formed in the inner peripheral surface of the gasket 28.
Multiple faller gills 26 have multiple zigzag needles 262 respectively along periphery at certain intervals.Also, in adjacent needle Drug delivery slot 263 is formed between 262.
A pair of of spool cap 242a, 242b include and 241 integrated first spool cap 242a of mesoporous main shaft and and First Line Second spool cap 242b of shaft-cup 242a assembling, and when the assembling of the second spool cap 242b and mesoporous main shaft 241 is released from, Xiang Zhong The peripheral surface of hole rotary shaft 241 can carry out the insertion or separation of annular faller gill 26 and annular gasket 28.In the mesoporous rotary shaft 241 peripheral surface is alternately arranged and is embedded in annular faller gill 26 and annular gasket 28, will be formed in the quadrangle of annular faller gill 26 First key 265 and the second key of quadrangle 285 for being formed in gasket 28, a row ground, which is embedded in, is formed in 241 peripheral surface of mesoporous rotary shaft Keyway 2412, and then annular faller gill 26 and annular gasket 28 are constrained on mesoporous rotary shaft 26 and can rotate integrally.In micropin In the assembling process of idler wheel, though a part of faller gill in multiple faller gills if problem occurs can by only replace corresponding faller gill into Row makes.
On the one hand, the rolling wheel support 22 includes:Basic courses department 221;And it is vertically formed in the front of the basic courses department 221 Face both sides, and a pair of of axis mounting wall 222,222 in face is faced each other, and it is rotatable in a pair of axis mounting wall 222,222 formation Ground is embedded in the axis hole 2224,2224 of the core rotary shaft 21.The pair of axis mounting wall 222 is respectively slidably embedded in above-mentioned Idler wheel guide clamp 14 guiding groove 142 (referring to figs. 1 to Fig. 3).
The valve operation portion 23 for constituting a drug delivery mechanism part is formed in the bottom surfaces of the basic courses department 221.The valve Operation portion 23 includes:Vertical with the basic courses department 221 and bottom surfaces center from the basic courses department 221 rearward extends in long way Bar portion 231;And it is formed in the tapered pressurization part 232 of 231 peripheral surface of the bar portion.The bar portion 231 is being formed in above-mentioned valve The round valve opening 1232 of film 123 (referring to figs. 1 to Fig. 3) is embedded in the sealing state in no subtle gap, and according to the micropin Moving up and down for idler wheel 20 moves up and down together.The tapered pressurization part 232 is formed in the centre of the bar portion 231, from bar Lower end of the portion 231 with same diameter to upper end of the diameter than the bar portion 231 with larger diameter there is diameter gradually to increase The shape added.When the bar portion 231 retreats the valve film 123 so that the tapered pressurization part 232 is pressurizeed, it is formed in the valve film 123 valve opening 1232 increases the diameter of the tapered pressurization part 232, and correspondingly its size is expanded therewith.On the one hand, from described The maximum outline border of diameter of tapered pressurization part 232 to the inside portion of the diameter minimum of the tapered pressurization part 232, i.e., to it is described The part that bar portion 231 connects forms drug and passes through splitted groove 233.The drug is by splitted groove 233 in the tapered pressurization part During the 232 pressurization valve openings 1232, allow passing through for drug.Pass through incision in 232 no drug of the tapered pressurization part When slot 233, even if 232 pressurizing valve film 123 of tapered pressurization part expands valve opening 1232, since valve opening 123 is blocked up by tapered pressurization part 232 Firmly without allowing drug passing through, but in the present embodiment, a part of field of the valve opening 1232 of expansion is with drug by cutting 233 connection of fluting, allows for passing through for drug.The tapered pressurization part 232 has the periphery phase the most in faller gill-gasket group For adjacent a pair of of drug by splitted groove 233, the pair of drug is formed in the position in the face of facing each other by splitted groove 233, with Drug can be supplied glibly by so that faller gill 26 is carried out rotation with any direction in counter clockwise direction clockwise.More specifically Ground is formed the pair of drug and is passed through incision in the form of parallel with the faller gill 26 bisection tapered pressurization part 232 Slot 233.
Fig. 6 is the view for showing the drug delivery mechanism for illustrating micro-needle roller device and acting on, with reference to a of Fig. 6, micro- In the state that needle pair of rollers skin is not pressed, bar portion 231 is embedded in the valve for being formed in silicon material valve film 123 in a sealed state Hole 1232 is blocked and is flowed out from the drug of medicine bottle 2.At this moment, no bar portion 231 and it is formed in the tapered pressurization part of the bar portion 231 232 retrogressing, therefore, valve film 123 are not pressurized, and are not also formed in the elastic dilatation of the valve opening 1232 of valve film 123 as a result,.
When micropin idler wheel is pressed against skin operation, bar portion 231 and tapered pressurization part 232 are one as shown in the b of Fig. 6 as a result, It rises and retreats, while valve film 123 is made its deformation to pusher, expand valve opening 1232.Tapered pressurization part 232 expands valve opening 1232 simultaneously Embedded in the valve opening 1232, therefore, valve opening 1232 passes through splitted groove 233 by being formed in the drug of the tapered pressurization part 232 It is opened, is stored in the drug of medicine bottle 2 as a result, by valve opening 1232 and drug by splitted groove 233, is out supplied from medicine bottle 2 To the faller gill of micropin idler wheel.

Claims (4)

1. a kind of micro-needle roller device can discretely be incorporated in medicine bottle, the medicine bottle stores liquid medicine, and includes having one Determine the bottleneck of internal diameter, which is characterized in that including:
Viscoplasticity connection cover covers the bottleneck upper end opening portion, and can discretely be incorporated in the medicine bottle;
Idler wheel guide clamp is incorporated in viscoplasticity connection cover upper end;
Micropin idler wheel is oriented to fixture in the idler wheel and maintains linear movement;And
Drug delivery mechanism, the micropin pair of rollers skin under pressure, by the drug delivery in the medicine bottle to described micro- The faller gill of needle idler wheel, wherein
When the viscoplasticity connection cover is incorporated in the medicine bottle upper end, including:
Lower part outer cylindrical portion is tightly attached to the bottleneck peripheral surface;
Lower tub portion is inserted in the medicine bottle opening portion, is tightly attached to the bottleneck inner peripheral surface;
Plate ring portion, connect the lower part outer cylindrical portion upper end Inner weeks and the lower tub portion upper end periphery while, tightly It is attached to the bottleneck upper end, and
The lower end of lower end and the bottleneck of the lower tub portion Jing Guo the lower part outer cylindrical portion more extends downwards.
2. micro-needle roller device according to claim 1, which is characterized in that
There is the annular protrusion protruded to radial direction, the viscoplasticity connection cover to be incorporated in lower end in the lower tub portion When the medicine bottle, the annular protrusion, with reinstatement, hangs over institute after by the inside bottle neck and contraction distortion It states the enlarged portion under the bottleneck lower end of bottleneck and is close to.
3. micro-needle roller device according to claim 2, which is characterized in that
The viscoplasticity connection cover includes:
Top outer cylindrical portion is tightly attached to the lower end sill lateral surface of the idler wheel guide clamp;
Upper inner cylinder portion has concentric shafts with the top outer cylindrical portion, and is formed on the inside of the top outer cylindrical portion;
Annular maintains lid, extends on the inside of top outer cylindrical portion upper end, and
The annular maintains lid to be embedded in the lower end sill of the idler wheel guide clamp inwardly, while so as to flexible deformation, institute The upper side that lower end sill are tightly attached to the lower end sill in the state of insertion is stated, it will be to seal the shape of the idler wheel guide clamp State is fixed on the viscoplasticity connection cover.
4. micro-needle roller device according to claim 3, which is characterized in that
The viscoplasticity connection cover is integrally included in the valve film of the hollow inner side formation valve opening in the upper inner cylinder portion,
The micropin idler wheel includes:
Rolling wheel support is arranged to move linearly up and down according to the guiding groove for being formed in the idler wheel guide clamp;
Core rotary shaft is arranged to rotate the rolling wheel support;
Idler wheel spool is arranged to rotate the core rotary shaft;
Multiple annular faller gills, rotate the core rotary shaft together with the idler wheel spool, and
The drug delivery mechanism includes valve operation portion, pulls together to transmit medicine from the medicine bottle to the faller gill side with the valve film Object,
Valve operation portion includes:
Bar portion, with the seamless state for being embedded in the valve opening and the micropin idler wheel integrally linear movement up and down;
Tapered pressurization part is formed in the centre of the bar portion, from lower end of the bar portion with same diameter to than institute The upper end of bar portion major diameter is stated, diameter gradually increases;
Drug is formed in the tapered pressurization part by splitted groove, and
When the tapered pressurization part pressurization valve film, the valve film is squeezed by the tapered pressurization part, and then expands the valve Hole, and the valve opening is connect with the drug and is opened by splitted groove in the state of being expanded by the tapered pressurization part It puts.
CN201780016670.4A 2016-11-08 2017-07-31 Microneedle roller device comprising viscoelastic connecting cover with bottle neck lower end clinging structure Active CN108778396B (en)

Applications Claiming Priority (3)

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KR10-2016-0147838 2016-11-08
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