CN108721519A - A kind of oral solution and preparation method thereof for tonifying kidney and strengthening yang - Google Patents
A kind of oral solution and preparation method thereof for tonifying kidney and strengthening yang Download PDFInfo
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Abstract
The invention belongs to health product technology fields, are related to a kind of oral solution and preparation method thereof for tonifying kidney and strengthening yang.The oral solution is made of following component in parts by weight：20~40 parts of Cortex Eucommiaes, 3~8 parts of oyster meats, 2~5 parts of RADIX POLYGONI MULTIFLORI PREPARATAs, 2~5 parts of psoralea corylifolias, 1~3 portion of Herba Cistanches, 3~8 parts of Radix Angelicae Sinensis, 2~5 portions of Radix Glycyrrhizaes, 3~8 parts of yellow rice wine and 30~50 parts of purified waters, kidney deficiency situation can be effectively improved, with efficacies of tonifying kidney and invigorating yang, and preparation method is simple and easy to do, it is suitable for exploitation into corresponding health products, great market prospects.
Description
Technical field
The invention belongs to health product technology field, it is related to a kind of oral solution of tonifying kidney and strengthening yang and preparation method thereof.
Background technology
Chinese medicine thinks that the kidney being the origin of congenital constitution, built-in nephroyin and nephroyang, and kidney deficiency refers to then that kidney vital essence negative and positive are insufficient.Kidney deficiency is divided into
The symptom of kidney-yang deficiency and kidney-yin deficiency, kidney-yang deficiency is " cold ", mainly there is the soreness of waist, coldness of extremities, chilly etc., even oedema occurs sometimes
And sexual function and reproductive dysfunction (such as the impotence of male, premature ejaculation, the palace cold of women, infertile), and the symptom of kidney-yin deficiency
For " heat ", mainly there are scorching, night sweat, dizziness, tinnitus etc., needs to select different treatment sides for different deficiency of the kidney
Method.Kidney-yang deficiency is then trembled with fear, cold then temperature, and based on tonifying kidney and strengthening yang, prescription can then take chinkuei shin chewan pills, three kidney balls, Yougui Wan, the kidney-Yang-Reinforcing Bolus etc.；
Kidney-yin deficiency is then hot, it is hot then it is clear it, based on nourishing Yin and clearing heat, prescription can then take Liuwei Dihuang Wan, the Pill of Anemarrhena, Phellodendrom and Rehmannia, Zuogui Wan
Deng.The appearance of deficiency of the kidney is mostly related with the long-term accumulated of bad life habits, can't blindness medication.
1057583 A of CN disclose a kind of preparation method of kidney-tonifying and yang-strengthening oral solution, and the formula of the oral solution includes dove
More than the 30 kinds of supplementary material ingredient such as son, black-bone chicken, sheep kidney, pizzle, Cornu Cervi Pantotrichum, hippocampus, sea otter, prescription is extremely complex, carries significantly
The difficulty of quality control in high production process, and include many animals source medicinal material in being formulated, it is unfavorable for large-scale promotion and answers
With；There is also similar problems for two kinds of kidney-tonifying and yang-strengthening oral solutions disclosed in 101780201 A of CN 1253174 C and CN.CN
1150025 A disclose a kind of tonifying kidney and strengthening yang drug kidney yang spring oral solution, include ginseng, Rhizoma Atractylodis Macrocephalae, radix rehmanniae preparata etc. more than 20 in formula
Kind supplementary material ingredient, prescription is equally complex, and the components such as single meat, Huaihe River, sheep work Thailand, leaves of pulse plants basin are not used Chinese medicine and lead
Specification term in domain causes intension unclear, can not implement.102613552 A of CN disclose a kind of raspberry tonifying kidney and strengthening yang mouth
Liquid is taken, which contains only a kind of raspberry this medicinal ingredient, and is made by specific preparation method, but this application is not
The pharmacology or pharmacodynamics test data of open product.
Cortex Eucommiae be Eucommiaceae Cortex Eucommiae platymiscium Cortex Eucommiae (Eucommia ulmoides Oliv.) bark, main product in Sichuan,
The provinces such as Yunnan, Guizhou, Hubei.Cortex Eucommiae is warm-natured, sweet in flavor, returns liver and kidney channel, for filling liver kidney, strengthening the bones and muscles, tocolysis.It is rich in Cortex Eucommiae
Lignanoids (such as Pinoresinol diglucoside), iridoids (such as eucommioside) and flavonoids (such as astragalin) ingredient.
Pharmacology of Chinese materia medica research shows that：Cortex Eucommiae have effects that a certain extent treat nephrosis, restore renal function, but using Cortex Eucommiae as
The oral solution of main component is not yet seen in document report.
Invention content
The purpose of the present invention is to provide it is a kind of with Cortex Eucommiae make the oral solution as main component for tonifying kidney and strengthening yang and its
Preparation method, to make up blank in the prior art.
To achieve the goals above, the present invention adopts the following technical scheme that：
A kind of oral solution for tonifying kidney and strengthening yang is made of following component in parts by weight：20~40 parts of Cortex Eucommiaes, 3
~8 parts of oyster meats, 2~5 parts of RADIX POLYGONI MULTIFLORI PREPARATAs, 2~5 parts of psoralea corylifolias, 1~3 portion of Herba Cistanches, 3~8 parts of Radix Angelicae Sinensis, 2~5 parts of Radix Glycyrrhizaes, 3~8
Part yellow rice wine, 30~50 parts of purified waters, preferably 30 parts of Cortex Eucommiaes, 6 parts of oyster meats, 4 parts of RADIX POLYGONI MULTIFLORI PREPARATAs, 4 parts of psoralea corylifolias, 2 parts of Herba Cistanches, 6
Part Radix Angelicae Sinensis, 4 portions of Radix Glycyrrhizaes, 6 parts of yellow rice wine, 40 parts of purified waters.
In above-mentioned oral solution, the oyster meat is Ostreidae oyster category mollusk oyster (Ostrea gigas
Thunberg meat), oyster is very wide in China's distribution, and North gets the Yalu River, to Hainan Island, coastal area can all cultivate in south.Oyster
Meat is mild-natured, sweet in flavor, salty, converge to heart and liver channels, subsides a swelling for nourishing blood and tranquilization, softening hard masses.Rich in glycogen, taurine, amino acid in oyster meat
Class (wherein leucine, arginine, the content of citrulling are the abundantest), vitamins (such as vitamin A, B1, B2, D) and nothing
Machine matter class (such as zinc, copper, manganese, barium, phosphorus and calcium) ingredient.
In above-mentioned oral solution, the RADIX POLYGONI MULTIFLORI PREPARATA be the fleece-flower root processed product, the fleece-flower root be polygonaceae fleece-flower root platymiscium what
The root tuber of the tuber of multiflower knotweed (Polygonum multiflorum Thunb.), China's most area are produced, when cauline leaf is withered after autumn
Or pick takes its root tuber before next year non-rudiment, cleans, slice dries, referred to as Radix Polygoni Multiflori, if mixing steaming with black soya bean liquor, becomes after drying
For black, referred to as RADIX POLYGONI MULTIFLORI PREPARATA.RADIX POLYGONI MULTIFLORI PREPARATA slightly warm in nature, it is bitter, sweet, puckery, return liver and kidney channel, for help essence and blood, preventing malaria, removing toxic substances, profit
Intestines defaecation.Anthraquinones (such as rheum emodin, Chrysophanol, Rhein, Chrysophanol methyl ether, chrysophanic acid anthrone) and Stilbene are rich in RADIX POLYGONI MULTIFLORI PREPARATA
Class (such as resveratrol, piceid) ingredient.
In above-mentioned oral solution, the psoralea corylifolia is pulse family Psoralea plant psoralea corylifolia (Psoralea
Corylifolia L.) seed, main product is in provinces such as Shaanxi, Henan, Jiangxi, Anhui, Sichuan, Yunnan.The big temperature of Psoralen lipid, taste
It is bitter, pungent, return kidney, the spleen channel, for tonifying kidney and strengthening yang, astringent sperm contracting urine, warming spleen and stopping diarrha.Coumarins (such as psoralea corylifolia is rich in psoralea corylifolia
Element, Isopsoralen, psoralidine, isopsoralidine, psoralea corylifolia furoeoumarin etc.), (such as psoralea corylifolia looks into ear to chalcone
Ketone, isobavachalcone, neobavachalcone, different neobavachalcone, psoralea corylifolia furans chalcone etc.) and benzo furan
Class of muttering (such as psoralea corylifolia benzofuran phenol, different psoralea corylifolia benzofuran phenol) ingredient.
In above-mentioned oral solution, the Herba Cistanches are Orobanchaceae Cistanche deserticola parasitic plant Herba Cistanches (Cistanche
Salsa (C.A.Mey.) G.Beck) the fleshy stem with scale leaf, main product is in provinces and regions such as the Inner Mongol, Gansu, Xinjiang, Qinghai.Meat desert
Rong is warm-natured, sweet in flavor, salty, returns kidney, large intestine channel, for tonifying the kidney and support yang, relaxing bowel.Benzyl carbinol glycoside (such as class is rich in Herba Cistanches
Verbascoside, Isoacteoside etc.) ingredient.
It is described to be classified as Umbelliferae archangel Radix Angelicae Sinensis (Angelica sinensis in above-mentioned oral solution
(Oliv.) Diels) root, main product is more with Minxian County (Qin Zhou) yield in the southeast of Gansu, high-quality, be secondly Shaanxi, Sichuan,
The provinces such as Yunnan, Hubei are cultivation product.Radix Angelicae Sinensis is warm-natured, sweet in flavor, pungent, Return liver, the heart, the spleen channel, for enriching blood, invigorating blood circulation, relieve pain, moisten
Intestines.Volatile oil ingredient (such as Ligustilide, butylidenephthalide, cymol) is rich in Radix Angelicae Sinensis.
In above-mentioned oral solution, the Radix Glycyrrhizae is pulse family glycyrrhiza genus Radix Glycyrrhizae (Glycyrrhiza uralensis
Fisch root), wild varieties are distributed mainly on Xinjiang, the Inner Mongol, Ningxia, Gansu, Shanxi, and artificial growth kind main product is in new
Boundary, the Inner Mongol, the Hexi Corridor in Gansu and countries of Ningxia Hui Autonomous Region area.Radix Glycyrrhizae is mild-natured, sweet in flavor, the thoughts of returning home, lung, spleen, stomach, for mending
Spleen QI invigorating moistens the lung and relieve the cough, relieving spasm to stop pain, mitigates pharmacological property.It is (such as sweet rich in triterpene saponin (such as glycyrrhizic acid) and flavonoids in Radix Glycyrrhizae
Careless element) ingredient.
In above-mentioned oral solution, the yellow rice wine be with rice, milled glutinous broomcorn millet, maize etc. for primary raw material, through adding the sugar such as song, yeast
Change fermented wine made of leavening brewing.Yellow rice wine is warm-natured, sweet in flavor, bitter, pungent, toxic, the thoughts of returning home, liver, lung, stomach, has promoting blood circulation logical
The effect of network, expelling wind and clearing away cold, for chill numbness pain, Spasm of the tendons, the obstruction of qi in the chest, trusted subordinate's crymodynia etc..Yellow rice wine belongs to low brewed wine,
In contain 12%~18% (v/v) ethyl alcohol, and containing maltose, glucose and succinic acid, lactic acid, amino acid, esters
With the ingredients such as aldehydes.
In above-mentioned oral solution, the purified water be by drinking water through the way of distillation, ion-exchange, hyperfiltration or other
Water for pharmaceutical purposes made from suitable method.
The preparation method of above-mentioned oral solution comprising following steps：
1) Cortex Eucommiae of formula ratio, oyster meat, RADIX POLYGONI MULTIFLORI PREPARATA, psoralea corylifolia, Herba Cistanches, Radix Angelicae Sinensis and Radix Glycyrrhizae are crushed respectively, crosses 80
~100 mesh sieve, and obtain Cortex Eucommiae powder, oyster digested tankage, RADIX POLYGONI MULTIFLORI PREPARATA powder, Psoralen cosmetics, Herba Cistanches powder, angelica powder and licorice powder；
2) by the ethyl alcohol of 3~5 times of volumes of mixture of the Cortex Eucommiae powder obtained in step 1), Psoralen cosmetics and Herba Cistanches powder
Refluxing extraction 10~15 hours filters out the dregs of a decoction after extraction, filtrate is concentrated into no alcohol taste, obtains medicinal extract I；It will be in step 1)
The methanol eddy extraction 5~10 of 3~5 times of volumes of the mixture of obtained oyster digested tankage, RADIX POLYGONI MULTIFLORI PREPARATA powder, angelica powder and licorice powder
Hour, the dregs of a decoction are filtered out after extraction, filtrate is concentrated into no alcohol taste, obtains medicinal extract II；
3) yellow rice wine of formula ratio is heated to 40~50 DEG C, is divided into after two parts and distinguishes dilution step 2) in obtained leaching
Cream I and medicinal extract II, by after dilution medicinal extract I and medicinal extract II be uniformly mixed, add the purified water of formula ratio, be uniformly mixed again
Low temperature sterilization and sterile filling are carried out afterwards, obtain the oral solution for tonifying kidney and strengthening yang.
In a preferred embodiment, Cortex Eucommiae described in step 1), oyster meat, RADIX POLYGONI MULTIFLORI PREPARATA, psoralea corylifolia, Herba Cistanches,
Radix Angelicae Sinensis and Radix Glycyrrhizae are dry product.
In a preferred embodiment, the mesh number sieved described in step 1) is 80 mesh.
In a preferred embodiment, Cortex Eucommiae powder described in step 2), Psoralen cosmetics and Herba Cistanches powder mixture
It is extracted 15 hours with the alcohol reflux of 5 times of volumes.
In a preferred embodiment, oyster digested tankage, RADIX POLYGONI MULTIFLORI PREPARATA powder, angelica powder and licorice powder processed described in step 2)
The methanol eddies of 3 times of volumes of mixture extract 10 hours.
In a preferred embodiment, the heating temperature of yellow rice wine described in step 3) is 50 DEG C.
The application method of above-mentioned oral solution is as follows：For the patient for deficiency of the kidney occur, after getting up and sleep daily
5~10mL of oral solution is respectively taken before feeling, is equipped with warm water delivery service, is used continuously 8~12 weeks, you can related symptoms are effectively relieved.
Compared with prior art, there are following advantages using the present invention of above-mentioned technical proposal：
1) lack in the prior art and the oral solution as main component for tonifying kidney and strengthening yang is made with Cortex Eucommiae, the present invention is exactly more
Above-mentioned blank has been mended, the application field of Cortex Eucommiae has been widened；
2) Cortex Eucommiae is assisted to play the effect of liver kidney is with benefit, tonifying kidney and strengthening yang using yang-tonifying drugs such as psoralea corylifolia and Herba Cistanches, it is auxiliary
It is acted on the nourishing the essence and strengthening QI of the replenishing and activating blood effect and oyster meat of RADIX POLYGONI MULTIFLORI PREPARATA and Radix Angelicae Sinensis, and is kept away come coordinating the drug actions of a prescription by Radix Glycyrrhizae
Exempt from the sense of discomfort that the intrinsic smell of traditional Chinese medicine ingredients is brought, improves the compliance of patient；
3) it is demonstrated experimentally that the oral solution prescription of the present invention is simple, can effective tonifying kidney and strengthening yang, and preparation method is simple and easy to do,
It is suitable for exploitation into corresponding health products, great market prospects.
Specific implementation mode
Technical scheme of the present invention is made below in conjunction with specific embodiment further elucidated above.The following example is only used
In the explanation and illustration present invention, and should not be taken as limiting the scope of the invention.Unless otherwise stated, institute in the following example
Instrument, reagent, material for using etc. can be obtained by routine business means.
Embodiment 1- embodiments 5：The preparation of oral solution for tonifying kidney and strengthening yang.
The oral solution for tonifying kidney and strengthening yang is prepared according to the formula in table 1, preparation process is as follows：
(1) dry Cortex Eucommiae, oyster meat, RADIX POLYGONI MULTIFLORI PREPARATA, psoralea corylifolia, Herba Cistanches, Radix Angelicae Sinensis and Radix Glycyrrhizae are crushed respectively, mistake
80 mesh sieve, and obtain Cortex Eucommiae powder, oyster digested tankage, RADIX POLYGONI MULTIFLORI PREPARATA powder, Psoralen cosmetics, Herba Cistanches powder, angelica powder and licorice powder；
(2) by 5 times of volume (embodiments of the mixture of the Cortex Eucommiae powder, Psoralen cosmetics and the Herba Cistanches powder that are obtained in step (1)
Dosage in 1~5 is respectively 140mL, 215mL, 200mL, 150mL and 180mL) alcohol reflux extract 15 hours, extracted
The dregs of a decoction are filtered out after finishing, filtrate is concentrated into no alcohol taste, obtains medicinal extract I；By the oyster digested tankage obtained in step (1), RADIX POLYGONI MULTIFLORI PREPARATA powder,
The mixture of angelica powder and licorice powder with 3 times of volumes (dosage in Examples 1 to 5 be respectively 78mL, 30mL, 45mL, 51mL and
Methanol eddy 60mL) extracts 10 hours, the dregs of a decoction is filtered out after extraction, filtrate is concentrated into no alcohol taste, obtains medicinal extract II；
(3) yellow rice wine is heated to 50 DEG C, is divided into the medicinal extract I and medicinal extract for distinguishing after two parts and being obtained in dilution step (2)
II, by after dilution medicinal extract I and medicinal extract II be uniformly mixed, add purified water, again after mixing carry out low temperature sterilization and
Sterile filling obtains the oral solution for tonifying kidney and strengthening yang.
Prescription and dosage of the table 1. for the oral solution of tonifying kidney and strengthening yang
Test example 1：The quality testing of oral solution of the present invention.
According to《GB 16740-2014 national food safety standard health foods》In detection project and detection method to reality
The oral solution applied in example 1~5 is detected, and the results are shown in Table 2.As shown in Table 2, indices are met the requirements of the standard.
The quality inspection result of 2. oral solution of table
Test example 2：The study on the stability of index components in oral solution of the present invention.
Oral solution in embodiment 5 is positioned at ambient temperature at shady and cool dry, the 1st after placement, 4,7,
10, it samples within 15 and 30 days, is calculated as 100% with the content of various active constituents in the 1st day sampling sample, measures each sub-sampling thereafter
The relative amount of middle tie element investigates storage stability of the oral solution under the drying condition of room temperature cool place whereby, and result is such as
Shown in table 3.
The storage stability result of index ingredient in 3. oral solution of table.
As shown in Table 3, in 30 days detection cycles, it is placed in chief active in the oral solution under the drying condition of room temperature cool place
The relative amount of ingredient can maintain 90% or more, show that the oral solution can be protected effectively in about 4 weeks storage times
Stay the activity of leading indicator ingredient.
Test example 3：The drug safety of oral solution of the present invention is investigated.
Content of the test：Acute toxicity test；Four genetic toxicity tests (are replied with reference to the bacterium of GB 15193.4-2014
Mutant test, with reference to the mammalian erythropoietin micronucleus test of GB 15193.5-2014, with reference to the small of GB 15193.7-2003
Mouse sperm malformation test, the Mouse Spermatogonial Cells chromosomal aberration test with reference to GB 15193.8-2014)；Rat tradition teratogenesis
Experiment；30 days feeding trials of rat.
Test result：The rats and mice LD50 of passing through mouth of two kinds of genders of oral solution pair of the present invention is all higher than 10g/kg weight, according to
Acute toxicity is classified, and belongs to practical non-poisonous material；Four genetic toxicity test results are feminine gender；Rat traditional teratogenicity test is not shown
Teratogenesis is shown；After 30 days feeding trials of rat, clinical indices, hematological indices and blood biochemical analysis index are just
Often, compared with the control group, difference is not notable for experimental group.
Test example 4：The health-care efficacy clinical test of oral solution of the present invention.
(1) subject：
60 subjects are male, average age 35 years old, wherein 40 subjects show soreness and weakness of waist and knees, dizziness ear
Ring, the symptoms such as hectic fever night sweat, there is also impotence and premature ejaculation symptoms, in addition 20 subjects not to show kidney deficiency by individual subject
Shape.
(2) application method：
40 kidney deficiency subjects are randomly divided into two groups, every group 20, are denoted as treatment group and blank control group respectively.To control
Treatment group subject uses the oral solution (specification in embodiment 5：10mL/ branch), 1 is respectively taken after getting up and before sleep daily,
It is equipped with a small amount of warm water delivery service, is used continuously 8 weeks.Blank control group subject does not take the oral solution in embodiment 5, daily in
A small amount of warm water is only taken after getting up and before sleep, is used continuously 8 weeks.
20 health volunteers are denoted as healthy control group, the oral solution (specification in embodiment 5 is used for it：10mL/
Branch), 1 is respectively taken after getting up and before sleep daily, is equipped with a small amount of warm water delivery service, is used continuously 8 weeks.
(3) test result：
After continuously taking oral solution 8 weeks, the deficiency of the kidney of 20 treatment group subjects significantly improves, waist and knee acid
The symptoms such as soft, dizziness and tinnitus, hectic fever night sweat disappear, and impotence and premature ejaculation symptom is eased existing for individual subject, wherein 40 years old
The morning vigorous situation of the above subject restores normal；In comparison, the deficiency of the kidney of 20 blank control group subjects does not improve.
In addition, 20 health volunteers, which continuously take oral solution, generally reflects that constitution and energy situation are improved after 8 weeks, and do not go out
Other existing adverse reactions.It can be seen that the oral solution of the present invention can be effectively improved kidney deficiency situation, there is efficacies of tonifying kidney and invigorating yang,
And drug safety, there are few adverse reactions.
Claims (8)
1. a kind of oral solution for tonifying kidney and strengthening yang, it is characterised in that：
The oral solution is made of following component in parts by weight：20~40 parts of Cortex Eucommiaes, 3~8 parts of oyster meats, 2~5 parts of systems are first
Crow, 2~5 parts of psoralea corylifolias, 1~3 portion of Herba Cistanches, 3~8 parts of Radix Angelicae Sinensis, 2~5 portions of Radix Glycyrrhizaes, 3~8 parts of yellow rice wine and 30~50 parts of purifying
Water.
2. the oral solution according to claim 1 for tonifying kidney and strengthening yang, it is characterised in that：
The oral solution is made of following component in parts by weight：30 parts of Cortex Eucommiaes, 6 parts of oyster meats, 4 parts of RADIX POLYGONI MULTIFLORI PREPARATAs, 4 parts of Psoralens
Fat, 2 portions of Herba Cistanches, 6 parts of Radix Angelicae Sinensis, 4 portions of Radix Glycyrrhizaes, 6 parts of yellow rice wine and 40 parts of purified waters.
3. the preparation method of the oral solution according to claim 1 or 2 for tonifying kidney and strengthening yang, it is characterised in that：
The preparation method includes the following steps：
1) Cortex Eucommiae of formula ratio, oyster meat, RADIX POLYGONI MULTIFLORI PREPARATA, psoralea corylifolia, Herba Cistanches, Radix Angelicae Sinensis and Radix Glycyrrhizae are crushed respectively, crosses 80~100
Mesh sieves, and obtains Cortex Eucommiae powder, oyster digested tankage, RADIX POLYGONI MULTIFLORI PREPARATA powder, Psoralen cosmetics, Herba Cistanches powder, angelica powder and licorice powder；
2) by the alcohol reflux of 3~5 times of volumes of mixture of the Cortex Eucommiae powder obtained in step 1), Psoralen cosmetics and Herba Cistanches powder
Extraction 10~15 hours, filters out the dregs of a decoction, filtrate is concentrated into no alcohol taste, obtains medicinal extract I after extraction；It will be obtained in step 1)
Oyster digested tankage, RADIX POLYGONI MULTIFLORI PREPARATA powder, angelica powder and licorice powder 3~5 times of volumes of mixture methanol eddy extraction 5~10 it is small
When, the dregs of a decoction are filtered out after extraction, filtrate is concentrated into no alcohol taste, obtains medicinal extract II；
3) yellow rice wine of formula ratio is heated to 40~50 DEG C, is divided into after two parts and distinguishes dilution step 2) in obtained medicinal extract I
With medicinal extract II, by after dilution medicinal extract I and medicinal extract II be uniformly mixed, add the purified water of formula ratio, again after mixing
Low temperature sterilization and sterile filling are carried out, the oral solution for tonifying kidney and strengthening yang is obtained.
4. preparation method according to claim 3, it is characterised in that：
Cortex Eucommiae described in step 1), oyster meat, RADIX POLYGONI MULTIFLORI PREPARATA, psoralea corylifolia, Herba Cistanches, Radix Angelicae Sinensis and Radix Glycyrrhizae are dry product.
5. preparation method according to claim 3, it is characterised in that：
The mesh number sieved described in step 1) is 80 mesh.
6. preparation method according to claim 3, it is characterised in that：
The alcohol reflux extraction 15 of 5 times of volumes of the mixture of Cortex Eucommiae powder described in step 2), Psoralen cosmetics and Herba Cistanches powder is small
When.
7. preparation method according to claim 3, it is characterised in that：
The methanol eddy of 3 times of volumes of mixture of oyster digested tankage processed described in step 2), RADIX POLYGONI MULTIFLORI PREPARATA powder, angelica powder and licorice powder
Extraction 10 hours.
8. preparation method according to claim 3, it is characterised in that：
The heating temperature of yellow rice wine described in step 3) is 50 DEG C.
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Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1541676A (en) * | 2003-11-06 | 2004-11-03 | 李德峰 | Health care medicine for enriching blood in puerperium and its preparation and uses |
| CN102613552A (en) * | 2012-03-29 | 2012-08-01 | 杨军 | Process for preparing raspberry kidney tonifying sexual function enhancing oral liquid |
| CN103040954A (en) * | 2012-12-20 | 2013-04-17 | 苏州天南星生物科技有限公司 | Potent kidney tonifying preparation |
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- 2017-04-25 CN CN201710275436.5A patent/CN108721519A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1541676A (en) * | 2003-11-06 | 2004-11-03 | 李德峰 | Health care medicine for enriching blood in puerperium and its preparation and uses |
| CN102613552A (en) * | 2012-03-29 | 2012-08-01 | 杨军 | Process for preparing raspberry kidney tonifying sexual function enhancing oral liquid |
| CN103040954A (en) * | 2012-12-20 | 2013-04-17 | 苏州天南星生物科技有限公司 | Potent kidney tonifying preparation |
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Application publication date: 20181102 |