CN108706323A - Full-automatic protein chip immunity analysis instrument chip feed mechanism - Google Patents
Full-automatic protein chip immunity analysis instrument chip feed mechanism Download PDFInfo
- Publication number
- CN108706323A CN108706323A CN201810715135.4A CN201810715135A CN108706323A CN 108706323 A CN108706323 A CN 108706323A CN 201810715135 A CN201810715135 A CN 201810715135A CN 108706323 A CN108706323 A CN 108706323A
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- CN
- China
- Prior art keywords
- chip
- thermal insulation
- lead screw
- insulation board
- chip carrier
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65G—TRANSPORT OR STORAGE DEVICES, e.g. CONVEYORS FOR LOADING OR TIPPING, SHOP CONVEYOR SYSTEMS OR PNEUMATIC TUBE CONVEYORS
- B65G47/00—Article or material-handling devices associated with conveyors; Methods employing such devices
- B65G47/74—Feeding, transfer, or discharging devices of particular kinds or types
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
- G01N35/04—Details of the conveyor system
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65G—TRANSPORT OR STORAGE DEVICES, e.g. CONVEYORS FOR LOADING OR TIPPING, SHOP CONVEYOR SYSTEMS OR PNEUMATIC TUBE CONVEYORS
- B65G2201/00—Indexing codes relating to handling devices, e.g. conveyors, characterised by the type of product or load being conveyed or handled
- B65G2201/02—Articles
- B65G2201/0214—Articles of special size, shape or weigh
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- Engineering & Computer Science (AREA)
- Mechanical Engineering (AREA)
- Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
Abstract
The present invention is full-automatic protein chip immunity analysis instrument chip feed mechanism, and structure includes thermal insulation board, lead screw motor, chip carrier, origin sensor, fibre optical sensor, upper and lower chip bounces cylinder and chip carrier moves left and right cylinder.Advantages of the present invention：It is simple in structure effective, with there are two chip carriers, fibre optical sensor can be detected chip, when there is no chip, the chip pushing block that lead screw motor drives can be the chip in a chip carrier to being pushed forward, and when having chip, lead screw motor stops operating, upper and lower chip, which bounces cylinder chip can be driven to bounce piece and move upwards, to bounce chip, chip is made to enter subsequent work stations.This feed mechanism realizes the chip automatic charging of full-automatic protein chip immunity analysis instrument, can once store a large amount of chips, improve work efficiency, and has saved artificial.When chip feed mechanism is run, preferred refrigeration module work, it is ensured that chip preserves use in suitable temperature, and the stability of temperature can be improved in thermal insulation thermal insulation board.
Description
Technical field
The present invention relates to full-automatic protein chip immunity analysis instrument chip feed mechanism,
Background technology
Protein chip is a kind of protein-function assays technology of high throughput, can be used for protein expression spectrum analysis, studies egg
The interaction of white matter and protein or even the interaction of DNA- protein, RNA- protein, screen pharmaceutically-active albumen
Target spot etc..
Protein chip carries out immunoassay using immunity analysis instrument, and immunity analysis instrument refers specifically to progress chemiluminescent labeling and exempts from
The instrument of epidemic disease analysis (also known as chemiluminescence immune assay), is the immunoassay with the direct labelled antigen of chemiluminescent agent or antibody
Method.
The protein chip immunity analysis instrument of the prior art generally comprises two parts, i.e. immune response system and chemiluminescence
Analysis system.Immune response system is used to luminescent substance (the generation excitation state intermediate under reaction solution excitation) being marked directly on
On antigen (chemiluminescence immune assay) or antibody (immunochemiluminometry) or enzyme effect is in luminous substrate.Chemiluminescence
Analysis system is used for the oxidation using catalysis and oxidant of the chemiluminescent substance through catalyst, forms the centre of an excitation state
Body when this excitation state intermediate returns to stable ground state, while launching photon (hM), utilizes luminous signal measuring instrument
Measure quantum yield of luminscence.
The generally each system of protein chip immunity analysis instrument and mechanism of the prior art are provided separately, and operation needs repeatedly artificial
Operation, efficiency is low, takes long, cannot achieve fully automatic operation.
Invention content
Proposed by the present invention is full-automatic protein chip immunity analysis instrument chip feed mechanism, and purpose is intended to overcome existing
Technology above shortcomings realize full-automatic protein chip immunity analysis instrument chip automatic charging.
Technical solution of the invention：Full-automatic protein chip immunity analysis instrument chip feed mechanism, structure include
Thermal insulation board, lead screw motor, chip carrier, origin sensor, fibre optical sensor, upper and lower chip bounce cylinder and chip carrier moves left and right
Cylinder, wherein thermal insulation board bottom set supporting leg, and the track that horizontally slips is set in thermal insulation board, and support is connected on the track that horizontally slips
Frame, supporting rack side connection chip carrier move left and right cylinder, two chip carriers being mutually parallel are set on supporting rack, chip carrier passes through
Positioning pin is limited with supporting rack, and chip catch is set in chip carrier, and the notch with the notch cooperation on chip, core are set on chip catch
Horse one end sets fibre optical sensor, and chip is set below the chip carrier of fibre optical sensor and bounces piece, chip bounces in piece connection
Lower chip bounces cylinder, and upper and lower chip bounces cylinder and is arranged in thermal insulation board, and the chip carrier other end sets origin sensor, and origin passes
Sensor light-blocking block is set by sensor, and chip pushing block, chip pushing block and lead screw motor are set on the inside of the chip carrier below origin sensor
Lead screw connection, the lead screw of lead screw motor is arranged in parallel in below chip carrier, and lead screw motor is arranged close to the chip carrier other end
Thermal insulation board side wall on.
Preferably, refrigeration module is set on the thermal insulation board side wall of the chip carrier side.
Advantages of the present invention：It is simple in structure that effectively with there are two chip carrier, fibre optical sensor can be detected chip,
When not having chip, the chip pushing block that lead screw motor drives can be the chip in a chip carrier to being pushed forward, and when having chip, lead screw is electric
Machine stops operating, and upper and lower chip, which bounces cylinder chip can be driven to bounce piece and move upwards, to bounce chip, so that chip is entered follow-up
Station.When the chip in a chip carrier is finished, chip pushing block is retracted initial position, origin sensor detection by lead screw motor
To chip pushing block, lead screw motor stops operating, and chip carrier moves left and right cylinder and supporting rack is driven to move left and right, by another chip
Frame pushes over, you can uses the chip in another chip carrier.This feed mechanism realizes full-automatic protein chip immunoassay
The chip automatic charging of instrument can once store a large amount of chips, improve work efficiency, and save artificial.Chip feed mechanism is transported
When row, preferred refrigeration module work, it is ensured that chip preserves use in suitable temperature, and temperature can be improved in thermal insulation thermal insulation board
Stability.
Description of the drawings
Fig. 1 is the dimensional structure diagram of full-automatic protein chip immunity analysis instrument chip feed mechanism of the invention.
Fig. 2 is the side schematic cross-sectional view of full-automatic protein chip immunity analysis instrument chip feed mechanism of the invention.
1 in figure it is thermal insulation board, 2 be supporting leg, 3 be refrigeration module, 4 be lead screw motor, 5 be chip pushing block, 6 is chip
Frame, 7 be supporting rack, 8 be origin sensor, 9 be sensor light-blocking block, 10 be chip catch, 11 be fibre optical sensor, 12 be core
Piece bounce piece, 13 be up and down chip bounce cylinder, 14 be horizontally slip track, 15 be that chip carrier moves left and right cylinder, 16 is core
Piece.
Specific implementation mode
With reference to embodiment and specific implementation mode, the present invention is described in further detail.
As shown in Figure 1 and Figure 2, full-automatic protein chip immunity analysis instrument chip feed mechanism, structure include thermal insulation board 1,
Lead screw motor 4, chip carrier 6, origin sensor 8, fibre optical sensor 11, upper and lower chip bounce cylinder 13 and chip carrier moves left and right
Cylinder 15, wherein 1 bottom of thermal insulation board set supporting leg 2, and the track 14 that horizontally slips is set in thermal insulation board 1, movable on the track 14 that horizontally slips
It is connected with supporting rack 7,7 side of supporting rack connection chip carrier moves left and right cylinder 15, two cores being mutually parallel are set on supporting rack 7
Horse 6, chip carrier 6 are limited by positioning pin and supporting rack 7, and chip catch 10 is set in chip carrier 6, are set on chip catch 10 and core
The notch of notch cooperation on piece 16,6 one end of chip carrier sets fibre optical sensor 11, under the chip carrier 6 of fibre optical sensor 11
Side sets chip and bounces piece 12, and chip, which bounces piece 12 and connects chip up and down, bounces cylinder 13, and upper and lower chip bounces the setting of cylinder 13 and exists
In thermal insulation board 1,6 other end of chip carrier sets origin sensor 8, and sensor light-blocking block 9, origin sensor 8 are set by origin sensor 8
6 inside of chip carrier of lower section sets chip pushing block 5, and chip pushing block 5 is connect with the lead screw of lead screw motor 4, and the lead screw of lead screw motor 4 is flat
Row is arranged below chip carrier 6, and lead screw motor 4 is arranged close on 1 side wall of thermal insulation board of 6 other end of chip carrier.
Refrigeration module 3 is set on 1 side wall of thermal insulation board of 6 side of chip carrier.
According to the above structure, when work, manually puts chip 16 well on chip carrier 6, pay attention to the positive negative side that chip 16 is placed
To chip carrier 6 is put into supporting rack 7, is set on supporting rack 7 for two by the notch of the notch alignment chip catch 10 of chip 16
The position that chip carrier 6 is placed, chip carrier 6 are limited by positioning pin.The detecting distance of fibre optical sensor 11 may be configured as 6mm, when
Fibre optical sensor 11 detects when not having chip that lead screw motor 4 can drive chip pushing block 5 the chip 16 in a chip carrier 6
To being pushed forward, when fibre optical sensor 11 has detected chip, lead screw motor 4 stops operating, and upper and lower chip bounces the drive of cylinder 13
Chip bounces piece 12 and moves upwards, and chip 16 is bounced, and the mechanical arm of such peripheral hardware can pick up the chip 16 bounced, under
One station.When the chip 16 in a chip carrier 6 is finished, chip pushing block 5 is retracted initial position, origin by lead screw motor 4
Sensor 8 detects that chip pushing block 5, lead screw motor 4 stop operating, and chip carrier moves left and right cylinder 15 and drives supporting rack 7 or so
It is mobile, another chip carrier 6 is pushed over, you can use the chip 16 in another chip carrier 6.Chip feed mechanism is run
When, preferred refrigeration module 3 is started to work, it is ensured that chip 16 preserves use in suitable temperature, and thermal insulation board 1 can be improved
The stability of temperature.
What has been described above is only a preferred embodiment of the present invention, it is noted that for those of ordinary skill in the art
For, without departing from the concept of the premise of the invention, various modifications and improvements can be made, these belong to the present invention
Protection domain.
Claims (2)
1. full-automatic protein chip immunity analysis instrument chip feed mechanism, feature include thermal insulation board, lead screw motor, chip carrier,
Origin sensor, fibre optical sensor, upper and lower chip bounce cylinder and chip carrier moves left and right cylinder, and wherein thermal insulation board bottom sets branch
Leg sets the track that horizontally slips in thermal insulation board, and supporting rack is connected on the track that horizontally slips, and supporting rack side connects chip carrier
Cylinder is moved left and right, two chip carriers being mutually parallel are set on supporting rack, chip carrier is limited by positioning pin and supporting rack, chip
Chip catch is set in frame, the notch with the notch cooperation on chip is set on chip catch, chip carrier one end sets fibre optical sensor, leans on
Chip is set below the chip carrier of dipped beam fiber sensor and bounces piece, and chip bounces piece connection, and chip bounces cylinder, upper and lower chip up and down
It bounces cylinder to be arranged in thermal insulation board, the chip carrier other end sets origin sensor, and sensor light-blocking block is set by origin sensor, former
Chip pushing block, the lead screw connection of chip pushing block and lead screw motor, the silk of lead screw motor are set on the inside of chip carrier below point sensor
Bar is arranged in parallel in below chip carrier, and lead screw motor is arranged close on the thermal insulation board side wall of the chip carrier other end.
2. full-automatic protein chip immunity analysis instrument chip feed mechanism as described in claim 1, it is characterized in that the core
Refrigeration module is set on the thermal insulation board side wall of horse side.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810715135.4A CN108706323A (en) | 2018-07-03 | 2018-07-03 | Full-automatic protein chip immunity analysis instrument chip feed mechanism |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810715135.4A CN108706323A (en) | 2018-07-03 | 2018-07-03 | Full-automatic protein chip immunity analysis instrument chip feed mechanism |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN108706323A true CN108706323A (en) | 2018-10-26 |
Family
ID=63872277
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201810715135.4A Pending CN108706323A (en) | 2018-07-03 | 2018-07-03 | Full-automatic protein chip immunity analysis instrument chip feed mechanism |
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| Country | Link |
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| CN (1) | CN108706323A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN117890452A (en) * | 2024-03-18 | 2024-04-16 | 深圳市真迈生物科技有限公司 | Chip transfer device, equipment and analysis system |
Citations (6)
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| US20050233325A1 (en) * | 2002-05-29 | 2005-10-20 | Fareed Kureshy | Integrated micro array system and methods therefor |
| CN105151755A (en) * | 2015-09-30 | 2015-12-16 | 迈得医疗工业设备股份有限公司 | Push structure of carrier on medical accessory assembly machine |
| CN106044181A (en) * | 2016-08-04 | 2016-10-26 | 浙江诺邦电子科技有限公司 | Transmission device |
| CN206827559U (en) * | 2017-05-17 | 2018-01-02 | 中山市松联电子科技有限公司 | A kind of computer memory bar connector automatic feeding |
| CN107840137A (en) * | 2017-07-07 | 2018-03-27 | 杭州中为光电技术股份有限公司 | The conveying caching workstation device that a kind of band is oriented to |
| CN208577126U (en) * | 2018-07-03 | 2019-03-05 | 无锡国盛生物工程有限公司 | Full-automatic protein chip immunity analysis instrument chip feed mechanism |
-
2018
- 2018-07-03 CN CN201810715135.4A patent/CN108706323A/en active Pending
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20050233325A1 (en) * | 2002-05-29 | 2005-10-20 | Fareed Kureshy | Integrated micro array system and methods therefor |
| CN105151755A (en) * | 2015-09-30 | 2015-12-16 | 迈得医疗工业设备股份有限公司 | Push structure of carrier on medical accessory assembly machine |
| CN106044181A (en) * | 2016-08-04 | 2016-10-26 | 浙江诺邦电子科技有限公司 | Transmission device |
| CN206827559U (en) * | 2017-05-17 | 2018-01-02 | 中山市松联电子科技有限公司 | A kind of computer memory bar connector automatic feeding |
| CN107840137A (en) * | 2017-07-07 | 2018-03-27 | 杭州中为光电技术股份有限公司 | The conveying caching workstation device that a kind of band is oriented to |
| CN208577126U (en) * | 2018-07-03 | 2019-03-05 | 无锡国盛生物工程有限公司 | Full-automatic protein chip immunity analysis instrument chip feed mechanism |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN117890452A (en) * | 2024-03-18 | 2024-04-16 | 深圳市真迈生物科技有限公司 | Chip transfer device, equipment and analysis system |
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