CN108700733A - 用于生成生物样本的具有增强景深的合成2d图像的系统 - Google Patents

用于生成生物样本的具有增强景深的合成2d图像的系统 Download PDF

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Publication number
CN108700733A
CN108700733A CN201780012672.6A CN201780012672A CN108700733A CN 108700733 A CN108700733 A CN 108700733A CN 201780012672 A CN201780012672 A CN 201780012672A CN 108700733 A CN108700733 A CN 108700733A
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CN
China
Prior art keywords
image data
depth
image
lateral position
focus
Prior art date
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Pending
Application number
CN201780012672.6A
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English (en)
Chinese (zh)
Inventor
J·P·温克
B·胡什肯
M·沃尔特斯
M·B·范莱文
S·H·尚德
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Koninklijke Philips NV
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Koninklijke Philips NV
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Publication date
Application filed by Koninklijke Philips NV filed Critical Koninklijke Philips NV
Priority to CN202411003807.0A priority Critical patent/CN118962955A/zh
Publication of CN108700733A publication Critical patent/CN108700733A/zh
Pending legal-status Critical Current

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    • HELECTRICITY
    • H04ELECTRIC COMMUNICATION TECHNIQUE
    • H04NPICTORIAL COMMUNICATION, e.g. TELEVISION
    • H04N23/00Cameras or camera modules comprising electronic image sensors; Control thereof
    • H04N23/60Control of cameras or camera modules
    • H04N23/67Focus control based on electronic image sensor signals
    • H04N23/676Bracketing for image capture at varying focusing conditions
    • GPHYSICS
    • G02OPTICS
    • G02BOPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00Microscopes
    • G02B21/36Microscopes arranged for photographic purposes or projection purposes or digital imaging or video purposes including associated control and data processing arrangements
    • G02B21/365Control or image processing arrangements for digital or video microscopes
    • G02B21/367Control or image processing arrangements for digital or video microscopes providing an output produced by processing a plurality of individual source images, e.g. image tiling, montage, composite images, depth sectioning, image comparison
    • GPHYSICS
    • G02OPTICS
    • G02BOPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00Microscopes
    • G02B21/0004Microscopes specially adapted for specific applications
    • G02B21/002Scanning microscopes
    • G02B21/0024Confocal scanning microscopes (CSOMs) or confocal "macroscopes"; Accessories which are not restricted to use with CSOMs, e.g. sample holders
    • G02B21/008Details of detection or image processing, including general computer control
    • GPHYSICS
    • G02OPTICS
    • G02BOPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00Microscopes
    • G02B21/24Base structure
    • G02B21/241Devices for focusing
    • G02B21/244Devices for focusing using image analysis techniques
    • GPHYSICS
    • G02OPTICS
    • G02BOPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B7/00Mountings, adjusting means, or light-tight connections, for optical elements
    • G02B7/28Systems for automatic generation of focusing signals
    • G02B7/36Systems for automatic generation of focusing signals using image sharpness techniques, e.g. image processing techniques for generating autofocus signals
    • G02B7/38Systems for automatic generation of focusing signals using image sharpness techniques, e.g. image processing techniques for generating autofocus signals measured at different points on the optical axis, e.g. focussing on two or more planes and comparing image data
    • GPHYSICS
    • G06COMPUTING OR CALCULATING; COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T5/00Image enhancement or restoration
    • G06T5/50Image enhancement or restoration using two or more images, e.g. averaging or subtraction
    • GPHYSICS
    • G06COMPUTING OR CALCULATING; COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T5/00Image enhancement or restoration
    • G06T5/73Deblurring; Sharpening

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  • Physics & Mathematics (AREA)
  • Engineering & Computer Science (AREA)
  • General Physics & Mathematics (AREA)
  • Multimedia (AREA)
  • Optics & Photonics (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Theoretical Computer Science (AREA)
  • General Engineering & Computer Science (AREA)
  • Signal Processing (AREA)
  • Microscoopes, Condenser (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Image Processing (AREA)
CN201780012672.6A 2016-02-22 2017-02-22 用于生成生物样本的具有增强景深的合成2d图像的系统 Pending CN108700733A (zh)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202411003807.0A CN118962955A (zh) 2016-02-22 2017-02-22 用于生成生物样本的具有增强景深的合成2d图像的系统

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP16156763.1 2016-02-22
EP16156763 2016-02-22
PCT/EP2017/053965 WO2017144482A1 (en) 2016-02-22 2017-02-22 System for generating a synthetic 2d image with an enhanced depth of field of a biological sample

Related Child Applications (1)

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CN202411003807.0A Division CN118962955A (zh) 2016-02-22 2017-02-22 用于生成生物样本的具有增强景深的合成2d图像的系统

Publications (1)

Publication Number Publication Date
CN108700733A true CN108700733A (zh) 2018-10-23

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CN202411003807.0A Pending CN118962955A (zh) 2016-02-22 2017-02-22 用于生成生物样本的具有增强景深的合成2d图像的系统

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Country Status (6)

Country Link
US (1) US10623627B2 (enExample)
EP (1) EP3420393B1 (enExample)
JP (2) JP7239324B2 (enExample)
CN (2) CN108700733A (enExample)
RU (1) RU2734447C2 (enExample)
WO (1) WO2017144482A1 (enExample)

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WO2018152071A1 (en) * 2017-02-15 2018-08-23 Flir Systems, Inc. Systems and methods for efficient enhanced image filtering by collaborative sharpening in similarity domain
WO2019068045A1 (en) 2017-09-29 2019-04-04 Leica Biosystems Imaging, Inc. FIXED Z SCANNING IN TWO AND THREE DIMENSIONS
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JP7098474B2 (ja) * 2018-08-07 2022-07-11 株式会社ミツトヨ 非接触式変位計
WO2021100328A1 (ja) * 2019-11-22 2021-05-27 ソニーグループ株式会社 画像処理方法、画像処理装置および画像処理システム
AU2020391126B2 (en) 2019-11-25 2024-11-21 Hologic, Inc. Digital imaging system and method
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KR102799293B1 (ko) * 2021-11-18 2025-04-29 한국광기술원 Z축 스캐닝을 포함하는 전체 슬라이드 이미지 생성 장치 및 방법
KR102802447B1 (ko) * 2022-04-05 2025-05-07 주식회사 뷰웍스 영상 획득 장치 및 영상 획득 방법
TW202431213A (zh) * 2022-09-28 2024-08-01 美商伊路米納有限公司 用於焦點追蹤的光點誤差處置
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Also Published As

Publication number Publication date
WO2017144482A1 (en) 2017-08-31
EP3420393A1 (en) 2019-01-02
JP2021073489A (ja) 2021-05-13
US20190075247A1 (en) 2019-03-07
US10623627B2 (en) 2020-04-14
JP7239324B2 (ja) 2023-03-14
RU2018133474A3 (enExample) 2020-05-15
CN118962955A (zh) 2024-11-15
JP7252190B2 (ja) 2023-04-04
EP3420393B1 (en) 2024-04-10
JP2019507384A (ja) 2019-03-14
RU2018133474A (ru) 2020-03-24
EP3420393C0 (en) 2024-04-10
RU2734447C2 (ru) 2020-10-16

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Application publication date: 20181023