CN108686133A - A kind of Chinese medicine improving thyroid cancer patients Postoperative Anxiety state - Google Patents

A kind of Chinese medicine improving thyroid cancer patients Postoperative Anxiety state Download PDF

Info

Publication number
CN108686133A
CN108686133A CN201810992232.8A CN201810992232A CN108686133A CN 108686133 A CN108686133 A CN 108686133A CN 201810992232 A CN201810992232 A CN 201810992232A CN 108686133 A CN108686133 A CN 108686133A
Authority
CN
China
Prior art keywords
chinese medicine
radix
thyroid cancer
anxiety state
fire
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201810992232.8A
Other languages
Chinese (zh)
Inventor
燕树勋
王颖
燕翔
王萍
党辉
潘研
万红
刘琳
余丹丹
刘元炜
郭盼盼
陈玲
燕苗苗
燕炳墨
万会娜
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Henan University of Traditional Chinese Medicine HUTCM
Original Assignee
Henan University of Traditional Chinese Medicine HUTCM
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Henan University of Traditional Chinese Medicine HUTCM filed Critical Henan University of Traditional Chinese Medicine HUTCM
Priority to CN201810992232.8A priority Critical patent/CN108686133A/en
Publication of CN108686133A publication Critical patent/CN108686133A/en
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/233—Bupleurum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/26—Iron; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56—Materials from animals other than mammals
    • A61K35/618—Molluscs, e.g. fresh-water molluscs, oysters, clams, squids, octopus, cuttlefish, snails or slugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56—Materials from animals other than mammals
    • A61K35/62—Leeches; Worms, e.g. cestodes, tapeworms, nematodes, roundworms, earth worms, ascarids, filarias, hookworms, trichinella or taenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56—Materials from animals other than mammals
    • A61K35/63—Arthropods
    • A61K35/648—Myriapods, e.g. centipedes or millipedes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/02—Algae
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06—Fungi, e.g. yeasts
    • A61K36/07—Basidiomycota, e.g. Cryptococcus
    • A61K36/076—Poria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/284—Atractylodes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/287—Chrysanthemum, e.g. daisy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/482—Cassia, e.g. golden shower tree
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/483—Gleditsia (locust)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484—Glycyrrhiza (licorice)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/51—Gentianaceae (Gentian family)
    • A61K36/515—Gentiana
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/536—Prunella or Brunella (selfheal)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/539—Scutellaria (skullcap)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/62—Nymphaeaceae (Water-lily family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/65—Paeoniaceae (Peony family), e.g. Chinese peony
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/704—Polygonum, e.g. knotweed
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/74—Rubiaceae (Madder family)
    • A61K36/744—Gardenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/75—Rutaceae (Rue family)
    • A61K36/752—Citrus, e.g. lime, orange or lemon
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/75—Rutaceae (Rue family)
    • A61K36/758—Zanthoxylum, e.g. pricklyash
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/80—Scrophulariaceae (Figwort family)
    • A61K36/804—Rehmannia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/888—Araceae (Arum family), e.g. caladium, calla lily or skunk cabbage
    • A61K36/8888—Pinellia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps

Abstract

The purpose of the present invention be just to provide it is a kind of improve thyroid cancer patients Postoperative Anxiety state Chinese medicine, the Chinese medicine by:Radix bupleuri, radix scutellariae, dried orange peel, the tuber of pinellia, caulis bambusae in taenian, the dried immature fruit of citron orange, rough gentian, cape jasmine, cassia seed, chrysanthemum, Radix Paeoniae Alba, radix rehmanniae recen, Polygonum multiflower knotweed, magnetite, mother-of-pearl, rhizoma nelumbinis, leech, centipede, spina gleditsiae, Chinese prickly ash, Radix Glycyrrhizae, Prunella vulgaris, seaweed, Poria cocos and Rhizoma Atractylodis Macrocephalae are made, above-mentioned Chinese medicine is mixed, add water, impregnate half an hour, it boils by intense fire, it uses instead and is cooked by slow fire 30 minutes, filtering, obtain the first filtrate, filter residue adds water, it boils by intense fire, it uses instead and is cooked by slow fire 30 minutes, filtering, obtain the second filtrate, it filtrate will be uniformly mixed twice, it is concentrated into 200-300ml, to obtain the final product;Pure Chinese medicine of the present invention is prepared, and is had the effect of clearing liver-fire, promoting blood circulation and removing blood stasis, is prevented and delay the recurrence and transfer of thyroid cancer, be the innovation on thyroid cancer postoperative rehabilitation drug, economic and social benefit is notable.

Description

A kind of Chinese medicine improving thyroid cancer patients Postoperative Anxiety state
Technical field
The present invention relates to Chinese medicine, especially a kind of Chinese medicine improving thyroid cancer patients Postoperative Anxiety state.
Background technology
Thyroid cancer is the more typical malignant tumour of incidence, accounts for l%~2% of whole body malignant tumour, common with women, can See any age bracket.The incidence of thyroid cancer is in notable ascendant trend at present.Thyroid cancer is divided into papillary adenocarcinoma, folliculus The multiple types such as shape cancer, undifferentiated carcinoma, cephaloma.Wherein papillary carcinoma clinic is most common, accounts for the 50%~70% of thyroid cancer. The therapy of this disease has operative treatment, radiotherapy, chemotherapy, endocrine therapy and Chinese medicine etc.." operation at present +131I treatments+thyroid hormone inhibits " it is acknowledged as the best comprehensive therapeutic plan of papillary carcinoma, transfer or recurrence can be reduced Rate.But for various reasons, the prognosis of curative effect and operation and unsatisfactory, therefore, improvement on drug and innovation gesture are must Row.In addition, people can usually ignore postoperative rehabilitation, though operation can cut off visible carcinoma, carcinoma can not be eliminated To the damage caused by human body, such as postoperative malaise symptoms, due to the double action of cancer and treatment to patient caused by psychology The transfer of burden and the carcinoma thus caused and recurrence etc. seriously affect its treatment and rehabilitation efficacy.In recent years, psychosomatics Development and society-psycho-physical medical model transformation, psychosocial factor is in the generation, development and prognosis of disease Important function be gradually realized.Thyroid cancer is postoperative because the exposure for a long time of operation wound, visual area, anesthesia influence, tracheae is inserted It is pipe damage, operation position, postoperative long term positional, postoperative131The combined causes such as I treatments, hypothyroidism, cause to suffer from Easily there is anxiety state in person.The incidence that the past research also shows thyroid cancer postoperative patient anxiety state is notable compared with general population It increases, prognosis, the quality of life etc. of the compliance, disease that the stress that patient is born treats it produce serious Negative effect.Alleviate anxiety, improve the mental health state of patient, to improving the quality of life of thyroid cancer postoperative patient It has a very important significance.More and more evidences show that traditional Chinese medicine is alleviating thyroid cancer patients postoperative psychology and body There is unique advantage in terms of body problem.According to examining for Chinese Spirit Obstacles classification and the 3rd edition (CCMD-3) anxiety disorder of diagnostic criteria Disconnected standard and common clinical symptoms see that anxiety state can belong to the emotional disorder scope of Chinese medicine, cover " melancholia ", " shy Probably ", " palpitation with fear ", " palpitaition ", " palpitation ", " being insomnia ", " hysteria ", " lily disease ", " lantern disease ", " up-rushing gas syndrome " etc., seriously affect The quality of life of patient, therefore, the improvement and innovation on the drug of improvement thyroid cancer patients Postoperative Anxiety state are imperative.
Invention content
For the above situation, to solve the defect of the prior art, the purpose of the present invention is just to provide a kind of improvement thyroid gland The anxiety state of thyroid cancer postoperative patient can be effectively relieved in the Chinese medicine of cancer patient's Postoperative Anxiety state, improve various clinical disease The problem of shape improves patient's immunity, reduces the financial burden, accelerates postoperative rehabilitation, improve patients ' life quality.
The technical solution that the present invention solves is that the Chinese medicine is by weight meter:Radix bupleuri 10-20g, radix scutellariae 15-20g, dried orange peel 15- 20g, tuber of pinellia 15-20g, caulis bambusae in taenian 15-20g, dried immature fruit of citron orange 10-15g, rough gentian 15-20g, cape jasmine 15-20g, cassia seed 20-30g, chrysanthemum 15-30g, Radix Paeoniae Alba 15-30g, radix rehmanniae recen 20-30g, Polygonum multiflower knotweed 20-30g, magnetite 15-20g, mother-of-pearl 20-30g, rhizoma nelumbinis 15- 20g, leech 3-9g, centipede 2-6g, spina gleditsiae 20-25g, Chinese prickly ash 3-6g, Radix Glycyrrhizae 6-12g, Prunella vulgaris 15-20g, seaweed 15- 20g, Poria cocos 15-20g and Rhizoma Atractylodis Macrocephalae 15-20g are made, wherein and above-mentioned Chinese medicine is mixed, the water of 6-8 times of Chinese medicine weight is added, Half an hour is impregnated, is boiled by intense fire, is used instead and be cooked by slow fire 30 minutes, filters, obtains the first filtrate, filter residue adds 6-8 times of Chinese medicine weight Water boils by intense fire, uses instead and is cooked by slow fire 30 minutes, and filtering obtains the second filtrate, filtrate will be uniformly mixed twice, and be concentrated into 200- 300ml to get.
Pure Chinese medicine of the present invention is prepared, and has the effect of clearing liver-fire, promoting blood circulation and removing blood stasis, it is postoperative can be effectively improved thyroid cancer Many clinical symptoms of patient anxiety's state, drug safety, accelerate patient postoperative rehabilitation, improve patients ' life quality, prevent and The recurrence and transfer for delaying thyroid cancer, are the innovations on thyroid cancer postoperative rehabilitation drug, and economic and social benefit is aobvious It writes.
Specific implementation mode
The specific implementation mode of the present invention is described in further detail below in conjunction with concrete condition and embodiment.
Embodiment 1
A kind of Chinese medicine improving thyroid cancer postoperative patient anxiety state of the present invention, the Chinese medicine is by weight meter:Radix bupleuri 13-18g, Radix scutellariae 16-18g, dried orange peel 17-19g, tuber of pinellia 16-18g, caulis bambusae in taenian 17-19g, dried immature fruit of citron orange 12-14g, rough gentian 16-18g, cape jasmine 17-19g, Cassia seed 23-27g, chrysanthemum 20-25g, Radix Paeoniae Alba 20-25g, radix rehmanniae recen 23-27g, Polygonum multiflower knotweed 23-27g, magnetite 16-19g, pearl Female 23-27g, rhizoma nelumbinis 16-18g, leech 5-8g, centipede 3-4g, spina gleditsiae 21-24g, Chinese prickly ash 4-5g, Radix Glycyrrhizae 8-10g, Prunella vulgaris 16-19g, seaweed 17-19g, Poria cocos 17-18g and Rhizoma Atractylodis Macrocephalae 16-18g are made, wherein mix above-mentioned Chinese medicine, add Chinese medicine The water of 6-8 times of weight impregnates half an hour, boils by intense fire, use instead and be cooked by slow fire 30 minutes, filters, the first filtrate is obtained, during filter residue adds The water of 6-8 times of medicine weight, boils by intense fire, uses instead and is cooked by slow fire 30 minutes, and filtering obtains the second filtrate, filtrate will mix twice It is even, it is concentrated into 200-300ml.
Embodiment 2
A kind of Chinese medicine improving thyroid cancer postoperative patient anxiety state of the present invention, the Chinese medicine is by weight meter:Radix bupleuri 10g, Huang A kind of reed mentioned in ancient books 15g, dried orange peel 15g, tuber of pinellia 15g, caulis bambusae in taenian 15g, dried immature fruit of citron orange 10g, rough gentian 15g, cape jasmine 15g, cassia seed 20g, chrysanthemum 15g, Radix Paeoniae Alba 15g, radix rehmanniae recen 20g, Polygonum multiflower knotweed 20g, magnetite 15g, mother-of-pearl 20g, rhizoma nelumbinis 15g, leech 3g, 1 g of centipede, spina gleditsiae 25g, flower Green pepper 3g, Radix Glycyrrhizae 6g, Prunella vulgaris 15g, seaweed 15g, Poria cocos 15g and Rhizoma Atractylodis Macrocephalae 15g are made, and the preparation method is the same as that of Example 1.
Embodiment 3
A kind of Chinese medicine improving thyroid cancer postoperative patient anxiety state of the present invention, the Chinese medicine is by weight meter:Radix bupleuri 15g, Huang A kind of reed mentioned in ancient books 18g, dried orange peel 18g, tuber of pinellia 18g, caulis bambusae in taenian 18g, dried immature fruit of citron orange 12g, rough gentian 18g, cape jasmine 18g, cassia seed 25g, chrysanthemum 20g, Radix Paeoniae Alba 20g, radix rehmanniae recen 25g, Polygonum multiflower knotweed 25g, magnetite 18g, mother-of-pearl 25g, rhizoma nelumbinis 18g, leech 6g, centipede 2g, spina gleditsiae 23g, flower Green pepper 3g, Radix Glycyrrhizae 10g, Prunella vulgaris 18g, seaweed 18g, Poria cocos 18g and Rhizoma Atractylodis Macrocephalae 18g are made, and the preparation method is the same as that of Example 1.
Embodiment 4
A kind of Chinese medicine improving thyroid cancer postoperative patient anxiety state of the present invention, the Chinese medicine is by weight meter:Radix bupleuri 20g, Huang A kind of reed mentioned in ancient books 20g, dried orange peel 20g, tuber of pinellia 20g, caulis bambusae in taenian 20g, dried immature fruit of citron orange 15g, rough gentian 20g, cape jasmine 20g, cassia seed 30g, chrysanthemum 30g, Radix Paeoniae Alba 30g, radix rehmanniae recen 30g, Polygonum multiflower knotweed 30g, magnetite 20g, mother-of-pearl 30g, rhizoma nelumbinis 20g, leech 9g, centipede 3g, spina gleditsiae 25g, flower Green pepper 6g, Radix Glycyrrhizae 12g, Prunella vulgaris 20g, seaweed 20g, Poria cocos 20g and Rhizoma Atractylodis Macrocephalae 20g are made, and the preparation method is the same as that of Example 1.
In said components, wherein:
Radix bupleuri:Soothing liver-qi stagnation, inducing diaphoresis are brought down a fever, and are risen and are lifted yang-energy.For stagnation of QI due to depression of the liver, exterior syndrome is generated heat, collapse from qi deficiency, internal organs prolapsus, Malaria fever and chills.
Radix scutellariae:Heat-clearing and damp-drying drug, purging intense heat and detonicating, hemostasis, tocolysis.For damp-warm syndrome, heat temperature, chest tightness and emesis, damp and hot feeling of fullness, jaundice Rush down dysentery, cough with lung heat, hyperpyrexia polydipsia.
Dried orange peel:Regulating qi-flowing for strengthening spleen is eliminating dampness and eliminating phlegm.For the taste stagnation of the circulation of vital energy, vomiting, hiccup, damp phlegm, cold productive cough are coughed, the obstruction of qi in the chest.
The tuber of pinellia:It is eliminating dampness and eliminating phlegm, stopping nausea and vomiting by lowering the adverse flow of QI, dissolving lump and resolving mass;Externally used detumescence relieves pain.For damp phlegm, cold-phlegm syndrome, vomiting, the heart Lower ruffian, accumulation of pathogens in chest, globus hysteriocus, goiter and tumor, subcutaneous nodule, swollen ulcer drug, venomous snake bite.
Caulis bambusae in taenian:Clearing heat and eliminating phlegm relieves restlessness and prevents vomiting.For cough with lung heat, the hot dysphoria and insomnia of phlegm, gastropyretic vomiting, pernicious vomiting spits Blood, bleeding from five sense organs or subcutaneous tissue, uterine bleeding.
The dried immature fruit of citron orange:Relieving stagnant Qi disperse accumulation, resolving sputum remove ruffian.It is damp and hot to let out dysentery for gastrointestinal retention, the obstruction of qi in the chest, accumulation of pathogens in chest, stagnation of the circulation of vital energy pain in chest and hypochondrium, Postpartum abdominal pain, dilatation of the stomach, gastroptosis, the prolapse of uterus, the internal organs such as rectal prolapse prolapsus disease.
Rough gentian:Heat-clearing and damp-drying drug, purging the liver of pathogenic fire courage fire.For jaundice with damp-heat pathogen, swelling of vulva pruritus vulvae, under band, eczema itch;Irascibility is had a headache, Hot eyes is deaf, hypochondriac pain bitter taste;Convulsion.
Cape jasmine:Purging intense heat relieving restlessness, clearing heat and promoting diuresis, removing pattogenic heat from the blood and toxic material from the body.For Vexed, jaundice with damp-heat pathogen, blood strangury and dry pain, blood-head spits Nosebleed, red eye, swell pain, pathogenic fire,toxin and furuncles.
Mother-of-pearl:It is calming the liver, it clears liver and improve vision, tranquillizing the mind by relieving convulsion.For rigid positive rising, have a dizzy spell, insomnia of palpitating with fear, the mind Not rather, cataract, blurring of vision, external application can treat itchy sore, and ulcer does not close up long, aphtha etc..
Rhizoma nelumbinis:Astringing to arrest bleeding.For haemorrhage.
Leech:Blood-breaking promoting menstruation, Zhu Yu Xiao Disorder.For blood stasis, a lump in the abdomen causing distension and pain, traumatic injury, trusted subordinate's pain.
Centipede:Ceases wind antispastic, dispersing pathogen accumulation are removed obstruction in channels to relieve pain.It twitches for spasm, sore swollen toxin, scrofula tuberculosis, rheumatism is stupid Numbness, intractable headache.
Spina gleditsiae:Detumescence and apocenosis, wind dispelling insecticide.For skin sore from the beginning of or purulence at not routed card, psoriasis, leprosy.
Chinese prickly ash:Warm in pain, desinsection are antipruritic.For syncope due to pathogenic cold abdominal pain, cold-dampness is vomited and diarrhoea, abdominal pain due to enterositosis, eczema, pruritus vulvae.
Radix Glycyrrhizae:It invigorates the spleen and benefits qi, expelling phlegm and arresting coughing, relieving spasm to stop pain is clearing heat and detoxicating, coordinating the drug actions of a prescription.For deficiency of heart-QI, kank Generation, severe palpilation, syndrome of deficiency of spleen qi, cough and asthma, gastral cavity abdomen, four limbs contraction, the only sore of heat, abscess of throat, medicine food poisoning, harmonizing drug Property.
Prunella vulgaris:Clearing heat-fire, improving eyesight, mass dissipating and swelling eliminating.For red eye, swell pain, dizziness of having a headache, mesh pearl nyctalgia, scrofula, goitre Tumor, acute mastitis pyogenic infections.
Seaweed:Dissolving phlegm softening hard masses, inducing diuresis for removing edema.For goiter and tumor, scrofula, testiclar gall, phlegm and retained fluid oedema.
Poria cocos:Clearing damp and promoting diuresis, invigorating the spleen, calming heart.For oedema, phlegm and retained fluid, splenasthenic diarrhea, palpitaition, sleep.
Rhizoma Atractylodis Macrocephalae:It replenishes qi to invigorate the spleen, eliminate dampness and have diuretic effect, hidroschesis, tocolysis.For syndrome of deficiency of spleen qi, spontaneous perspiration due to deficiency of vital energy, spleen deficiency fetal irritability.
Above-mentioned component science, reasonable compatibility support there is the effect of clearing liver-fire, promoting blood circulation and removing blood stasis, effective for controlling mutually Thyroid cancer patients Postoperative Anxiety state, good effect are treated, drug safety is treatment thyroid cancer patients Postoperative Anxiety state drug On innovation, and obtained fully proving through clinical data, related clinical data is as follows:
(One), case selection standard:
A, inclusion criteria:
(1)Age between 19-50 Sui, no organic disease;
(2)According to clinical symptoms, sign, auxiliary examination etc. as a result, meeting thyroid cancer Postoperative Anxiety condition diagnosing standard;
(3)It will be appreciated that gauge content and the problem of can accurately answer the question;
(4)Through Chinese medical discrimination category hyperactivity of heart-liver fire, blood-stasis syndrome;
(5)There is fixed effective contact method, patient or family members can use wechat app person;
(6)Know the purpose of this research, signs informed consent form, this research is voluntarily added.
B, exclusion criteria:
(1)Gestation, nursing period, plan are in a short time(6 months)Pregnancy person;
(2)Angiocarpy, Liver and kidney function seriously damages or other malignant diseases person;
(3)It cannot understand gauge content, it cannot be with people normal communication person;
(4)Mental patient, cognition dysfunction, be in a bad way cannot positive cooperation person;
(5)Receive other Chinese medicines, glucocorticoid and other immunosuppressant treatment persons;
(6)Other drugs clinical test person is participated in nearly March.
C, standard is rejected:
(1)Researcher cannot be participated in because sb.'s illness took a turn for the worse;
(2)Because of other reasons voluntarily bolter;
(3)Scale is assessed in research process does not complete person.
(Two), diagnostic criteria
(1)It is made a definite diagnosis through preoperative B ultrasound, thyroid gland radioisotope scanning or needle biopsy, and first is diagnosed as through verified by postoperative pathology Shape gland cancer;With or without abnormal thyroid function;
(2)Through " Analysisof Self-rating Anxiety Scale(SAS)" it is measured as anxiety state;
(3)Chinese medical discrimination is hyperactivity of heart-liver fire, blood-stasis syndrome:Nervous, worry, frightened, vexed, being irritable and getting angry easily, the distending pain in hypochondrium, face Portion warms, hot eyes, tinnitus, says active, dysphoria with smothery sensation hidrosis more, palm of the hand arch of the foot hidrosis, has palpitation, finger tremor, dry throat, redness, Shouting pain, dry mouth with bitter taste, cool drink, polyorexia, noisy acid regurgitation, dampness of scrotum, insomnia and dreamful sleep, operation on neck position scar are red Swollen, subcutaneous accessible scleroma has tenderness, changes one's position, come back limited, urine Huang, dry and hard excrement, purplish tongue or red tongue with a little fluid, tongue It is yellow or yellow thick greasy, wiry and frequent pulse or sliding number.
(Three), efficacy assessment standard:
Comprehensive therapeutic effect criterion:Including SAS scores difference, Chinese medicine syndrome integral difference.
SAS standards of grading:The cut off value of SAS standard point is 50 points, and wherein < 50 divides for no anxiety, and 50~59 points are slight Anxiety, 60~69 points are moderate anxiety, and 70 points or more are severe anxiety.
Chinese medicine syndrome integral:Calculation formula:(Prior treatment integral-post treatment integral)/ prior treatment integral, with percentage table Show.
Recovery from illness:Symptom and sign disappears substantially, and integral is greater than or equal to 95%;
It is effective:Symptom and sign is obviously improved, and integral integral is greater than or equal to 75%;
Effectively:Symptom and sign take a favorable turn, and integral is greater than or equal to 50%;
In vain:Symptom and sign is not improved, even aggravating, is integrated less than 50%.
(Four), therapeutic scheme:
To being diagnosed as the patient of thyroid cancer Postoperative Anxiety state, treated with the Chinese medicine of the present invention, when taking, the morning and evening each one Secondary, each 100-150ml, two hours cool clothes after meal, 7 days as a course for the treatment of, and curative effect is counted after 4 courses for the treatment of.
(Five), statistical procedures:
Selected patient totally 56, wherein man 20, female 36, the age be (37.8 ± 13.1) year, no rejecting case.By above-mentioned (Four)Therapeutic scheme, the Chinese medicine that the oral present invention provides count after 4 courses for the treatment of, clinical recovery 11, it is 19 effective, effective 23 Example, 3 invalid, total effective rate shows that invention Chinese medicine treatment thyroid cancer patients Postoperative Anxiety state effect is aobvious up to 94.6% It writes, has reached clinical treatment purpose, and over the course for the treatment of, had no obvious adverse reaction.
(Six), model case
For more detailed description treatment, the effect of model case and treatment is given below situation:
Case 1:Zhang, man, 45 years old, usually edgy, nervous, the pungent greasy product of eating.Thyroid papillary carcinoma Postoperative being irritable and irascible in January aggravates, nervous, frightened, pain over the hypochondriac region, dysphoria with smothery sensation hidrosis, palm of the hand arch of the foot hidrosis, bitter taste, big constipation Knot, operative scar position is red and swollen, and scleroma has tenderness.Red tongue body, yellow tongue fur, wiry and frequent pulse.It is measured as severe anxiety state through SAS.Clothes After 1 course for the treatment of of this Chinese medicine, patient's above-mentioned symptom gradually mitigates;After 3 courses for the treatment of, symptom and sign disappears substantially, and SAS measurement does not reach To anxiety state.
Case 2:Chen, female, 43 years old, papillary thyroid carcinoma was postoperative, and the clear first of radioiodine treats gradually appearing property after January Feelings being irritable and getting angry easily, nervous, vexed, fullness in chest and hypochondrium, Facial flush, hot eyes are easy to perspire, bitter taste and dry, finger tremor, neck Operative site is red and swollen, scleroma, changes one's position, come back limited, insomnia, dreaminess.Purplish tongue, moss thin yellow, wiry and frequent pulse.It is measured as through SAS Severe anxiety state.After taking 2 courses for the treatment of of this Chinese medicine, patient's above-mentioned symptom gradually mitigates;After 4 courses for the treatment of, symptom and sign is apparent Improve, SAS is measured as mild anxiety state.
Case 3:Week certain, female, 37 years old, thyroid papillary carcinoma postoperative half a month gradually appeared being irritable and getting angry easily, and chest expires bored pain Bitterly, say active, flushing, dysphoria with smothery sensation hidrosis, palm of the hand arch of the foot is apparent, has palpitation, bitter taste, hot eyes, noisy acid regurgitation, constipation, operation more Skin area is red and swollen, stiff, and subcutaneous accessible scleroma, tenderness is apparent, neck limitation of activity, dark tongue quality, yellow tongue fur, wiry and frequent pulse.Through SAS is measured as moderate anxiety state.After taking 1 course for the treatment of of this Chinese medicine, patient's above-mentioned symptom gradually mitigates, and SAS measurement is not up to Anxiety state;After 4 courses for the treatment of, symptom and sign disappears substantially, and SAS measures normal.
Case 4:Sun, man, 52 years old, thyroid papillary carcinoma was postoperative, and radioiodine gradually appears urgency after clear first treatment January Hot-tempered irritability is worried, frightened, pain over the hypochondriac region, dysphoria with smothery sensation, is easy to perspire, have palpitation, finger tremor, dry, bitter taste, hot eyes, tinnitus, pharynx Laryngoxerosis, redness, shouting pain, polyorexia, dampness of scrotum, operative scar position congestion and swelling pain subcutaneously have scleroma, there is tenderness, neck Portion's limitation of activity involves pain when movable, insomnia, dimly red tongue, yellow tongue fur, thready rapid pulse.It is measured as severe anxiety state through SAS. After taking 2 courses for the treatment of of this Chinese medicine, patient's above-mentioned symptom gradually improves;After 4 courses for the treatment of, malaise symptoms disappear substantially, and SAS measures knot Fruit is normal.
(Seven), conclusion
Chinese medicine of the present invention accordingly takes the treatments such as clearing liver-fire, promoting blood circulation and removing blood stasis to arrange on the basis of organic conception, diagnosis and treatment It applies, in reduction of patient anxiety state, improves malaise symptoms, patient can be improved while improving the adverse reaction that operation itself is brought Immunity reduces the financial burden, and then accelerates patient postoperative rehabilitation, prevents and delay the recurrence and transfer of thyroid cancer, is to use In the active drug for improving thyroid cancer postoperative patient anxiety state, effective percentage has no toxic side effect, curative effect is steady up to 94.6% or more It is fixed, it is the innovation treated on thyroid cancer patients Postoperative Anxiety state drug securely and reliably, economic and social benefit is notable.

Claims (5)

1. a kind of Chinese medicine improving thyroid cancer postoperative patient anxiety state, which is characterized in that the Chinese medicine is by weight meter:Radix bupleuri 10-20g, radix scutellariae 15-20g, dried orange peel 15-20g, tuber of pinellia 15-20g, caulis bambusae in taenian 15-20g, dried immature fruit of citron orange 10-15g, rough gentian 15-20g, cape jasmine 15-20g, cassia seed 20-30g, chrysanthemum 15-30g, Radix Paeoniae Alba 15-30g, radix rehmanniae recen 20-30g, Polygonum multiflower knotweed 20-30g, magnetite 15- 20g, mother-of-pearl 20-30g, rhizoma nelumbinis 15-20g, leech 3-9g, centipede 2-6g, spina gleditsiae 20-25g, Chinese prickly ash 3-6g, Radix Glycyrrhizae 6- 12g, Prunella vulgaris 15-20g, seaweed 15-20g, Poria cocos 15-20g and Rhizoma Atractylodis Macrocephalae 15-20g are made, wherein are blended in above-mentioned Chinese medicine Together, add the water of 6-8 times of Chinese medicine weight, impregnate half an hour, boil by intense fire, use instead and be cooked by slow fire 30 minutes, filter, obtain the first filter Liquid, filter residue add the water of 6-8 times of Chinese medicine weight, boil by intense fire, use instead and are cooked by slow fire 30 minutes, and filtering obtains the second filtrate, will twice Filtrate is uniformly mixed, and is concentrated into 200-300ml.
2. the Chinese medicine according to claim 1 for improving thyroid cancer postoperative patient anxiety state, which is characterized in that the Chinese medicine By weight meter:Radix bupleuri 13-18g, radix scutellariae 16-18g, dried orange peel 17-19g, tuber of pinellia 16-18g, caulis bambusae in taenian 17-19g, dried immature fruit of citron orange 12-14g, Rough gentian 16-18g, cape jasmine 17-19g, cassia seed 23-27g, chrysanthemum 20-25g, Radix Paeoniae Alba 20-25g, radix rehmanniae recen 23-27g, Polygonum multiflower knotweed 23-27g, magnetite 16-19g, mother-of-pearl 23-27g, rhizoma nelumbinis 16-18g, leech 5-8g, centipede 3-4g, spina gleditsiae 21-24g, Chinese prickly ash 4-5g, Radix Glycyrrhizae 8-10g, Prunella vulgaris 16-19g, seaweed 17-19g, Poria cocos 17-18g and Rhizoma Atractylodis Macrocephalae 16-18g are made.
3. the Chinese medicine according to claim 1 for improving thyroid cancer postoperative patient anxiety state, which is characterized in that the Chinese medicine By weight meter:Radix bupleuri 10g, it radix scutellariae 15g, dried orange peel 15g, tuber of pinellia 15g, caulis bambusae in taenian 15g, dried immature fruit of citron orange 10g, rough gentian 15g, cape jasmine 15g, determines Pine torch 20g, chrysanthemum 15g, Radix Paeoniae Alba 15g, radix rehmanniae recen 20g, Polygonum multiflower knotweed 20g, magnetite 15g, mother-of-pearl 20g, rhizoma nelumbinis 15g, leech 3g, Centipede 1g, spina gleditsiae 25g, Chinese prickly ash 3g, Radix Glycyrrhizae 6g, Prunella vulgaris 15g, seaweed 15g, Poria cocos 15g and Rhizoma Atractylodis Macrocephalae 15g are made.
4. the Chinese medicine according to claim 1 for improving thyroid cancer postoperative patient anxiety state, which is characterized in that the Chinese medicine By weight meter:Radix bupleuri 15g, it radix scutellariae 18g, dried orange peel 18g, tuber of pinellia 18g, caulis bambusae in taenian 18g, dried immature fruit of citron orange 12g, rough gentian 18g, cape jasmine 18g, determines Pine torch 25g, chrysanthemum 20g, Radix Paeoniae Alba 20g, radix rehmanniae recen 25g, Polygonum multiflower knotweed 25g, magnetite 18g, mother-of-pearl 25g, rhizoma nelumbinis 18g, leech 6g, Centipede 2g, spina gleditsiae 23g, Chinese prickly ash 3g, Radix Glycyrrhizae 10g, Prunella vulgaris 18g, seaweed 18g, Poria cocos 18g and Rhizoma Atractylodis Macrocephalae 18g are made.
5. the Chinese medicine according to claim 1 for improving thyroid cancer postoperative patient anxiety state, which is characterized in that the Chinese medicine By weight meter:Radix bupleuri 20g, it radix scutellariae 20g, dried orange peel 20g, tuber of pinellia 20g, caulis bambusae in taenian 20g, dried immature fruit of citron orange 15g, rough gentian 20g, cape jasmine 20g, determines Pine torch 30g, chrysanthemum 30g, Radix Paeoniae Alba 30g, radix rehmanniae recen 30g, Polygonum multiflower knotweed 30g, magnetite 20g, mother-of-pearl 30g, rhizoma nelumbinis 20g, leech 9g, Centipede 3g, spina gleditsiae 25g, Chinese prickly ash 6g, Radix Glycyrrhizae 12g, Prunella vulgaris 20g, seaweed 20g, Poria cocos 20g and Rhizoma Atractylodis Macrocephalae 20g are made.
CN201810992232.8A 2018-08-29 2018-08-29 A kind of Chinese medicine improving thyroid cancer patients Postoperative Anxiety state Pending CN108686133A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201810992232.8A CN108686133A (en) 2018-08-29 2018-08-29 A kind of Chinese medicine improving thyroid cancer patients Postoperative Anxiety state

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201810992232.8A CN108686133A (en) 2018-08-29 2018-08-29 A kind of Chinese medicine improving thyroid cancer patients Postoperative Anxiety state

Publications (1)

Publication Number Publication Date
CN108686133A true CN108686133A (en) 2018-10-23

Family

ID=63841433

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201810992232.8A Pending CN108686133A (en) 2018-08-29 2018-08-29 A kind of Chinese medicine improving thyroid cancer patients Postoperative Anxiety state

Country Status (1)

Country Link
CN (1) CN108686133A (en)

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103656539A (en) * 2014-01-06 2014-03-26 河南中医学院 Chinese medicament for improving excessive liver fire syndrome after thyroid carcinoma surgery
CN104491291A (en) * 2014-12-17 2015-04-08 崔合芳 Traditional Chinese medicine composition for treating liver-yang hyperactivity type thyroid adenoma
CN104524437A (en) * 2014-12-11 2015-04-22 青岛市肿瘤医院 Traditional Chinese medicine formula for treating thyroid carcinoma and preparation method of granules of traditional Chinese medicine formula

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103656539A (en) * 2014-01-06 2014-03-26 河南中医学院 Chinese medicament for improving excessive liver fire syndrome after thyroid carcinoma surgery
CN104524437A (en) * 2014-12-11 2015-04-22 青岛市肿瘤医院 Traditional Chinese medicine formula for treating thyroid carcinoma and preparation method of granules of traditional Chinese medicine formula
CN104491291A (en) * 2014-12-17 2015-04-08 崔合芳 Traditional Chinese medicine composition for treating liver-yang hyperactivity type thyroid adenoma

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
刘华等: "柴芩温胆汤加减治疗失眠症伴焦虑30例", 《中国医药科学》 *

Similar Documents

Publication Publication Date Title
CN104491295B (en) A kind of Chinese medicine composition for treating Stein-Leventhal syndrome
CN104523865B (en) Medicine for treating breast diseases
CN103751310A (en) External traditional Chinese medicinal preparation for treating fasciitis and preparation method thereof
CN103285284B (en) Medical composition for treating senile vaginitis
CN103083616B (en) Traditional Chinese medicine for treating ovarian cyst
CN103585609A (en) Traditional Chinese medicine composition for treating dysmenorrhea and preparation method thereof
CN103223122A (en) Traditional Chinese medicine for treating stubborn headache
CN108686133A (en) A kind of Chinese medicine improving thyroid cancer patients Postoperative Anxiety state
CN106389557B (en) A kind of Chinese medicine composition and its preparation method and application for Chinese medicine moxibustion
CN105434739A (en) Traditional Chinese medicine composition for treating chalazia and preparation method thereof
CN108815471A (en) A kind of Chinese medicine improving the postoperative insomnia of thyroid cancer
CN105943644B (en) A kind of Chinese medicine moxibustion composition and its preparation method and application for lumbar muscle strain
CN105833209B (en) Traditional Chinese medicine composition for treating endometriosis
CN105232864A (en) Traditional Chinese medicine clysis preparation for treating qi stagnation and blood stasis endometriosis
CN105596620A (en) Chinese herbal medicine for treating miscellaneous gynecological diseases
CN106266970B (en) A kind of Chinese medicine composition treated production and cause endometritis
CN104721737A (en) External preparation for hyperplasia of mammary glands
CN108853457A (en) A kind of Chinese medicine improving the postoperative gastrointestinal tract malaise symptoms of thyroid cancer patients
CN104436073A (en) Traditional Chinese medicine for treating hyperplasia of mammary glands
CN105125935A (en) Traditional Chinese medicine composition for treating kidney deficiency, liver depression and dampness-heat type tubal infertility
CN117771316A (en) Traditional Chinese medicine composition for moxa sticks
CN115887540A (en) Traditional Chinese medicine for treating sequelae of damp-heat stasis type pelvic inflammatory disease
CN104740040A (en) Traditional Chinese medicine decoction for treating irregular menstruation
CN104623562A (en) Pharmaceutical composition for treating hyperplasia of mammary glands and breast tumors
CN103463548B (en) A kind of Chinese medicine composition for the treatment of puerpera&#39;s galactostasis

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
RJ01 Rejection of invention patent application after publication

Application publication date: 20181023

RJ01 Rejection of invention patent application after publication