CN103223122A - Traditional Chinese medicine for treating stubborn headache - Google Patents
Traditional Chinese medicine for treating stubborn headache Download PDFInfo
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- CN103223122A CN103223122A CN2013102031067A CN201310203106A CN103223122A CN 103223122 A CN103223122 A CN 103223122A CN 2013102031067 A CN2013102031067 A CN 2013102031067A CN 201310203106 A CN201310203106 A CN 201310203106A CN 103223122 A CN103223122 A CN 103223122A
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Abstract
The invention relates to a traditional Chinese medicine for treating stubborn headache, effectively solving the pharmaceutical problem of treating stubborn headache. The technical scheme is that the medicine comprises the following components by weight: 20-30g of Ligusticum wallichii, 10-15g of radix angelicae, 6-10g of prepared rhizoma cyperi, 20-30g of radix paeoniae alba, 10-15g of gastrodia elata, 10-15g of stiff silkworm, 10-15g of Angelica sinensis, 5-10g of asarum, 6-10g of radices sileris, and 6-10g of earthworm. The method for preparing the medicine comprises the following steps of: soaking the components in water for 30 minutes; adding 4-6 times of water in weight compared with Ligusticum wallichii, radix angelicae, prepared rhizoma cyperi, gastrodia elata, stiff silkworm, Angelica sinensis, asarum, radices sileris and earthworm; decocting by high heat, and then decocting for 25-35 minutes by soft fire; filtering to obtain a primary filtrate; adding 3 times of water in weight compared with prepared rhizoma cyperi, radix paeoniae alba, gastrodia elata, stiff silkworm, Angelica sinensis, asarum, radices sileris and earthworm; decocting by high heat, and then decocting for 25-35 minutes by soft fire; filtering to obtain a secondary filtrate; and combining the filtrates and uniformly mixing the filtrates. The medicine provided by the invention is safe in high heat and free from toxic and side effects, and can be used for effectively treating stubborn headache. The medicine is innovation in medicines for treating stubborn headache.
Description
Technical field
The present invention relates to medicine, particularly a kind of Chinese medicine for the treatment of intractable headache.
Background technology
Intractable headache is a common clinical, frequently-occurring disease, migraine is the common type of intractable headache, belong to nerve, vascular headache, the women is more than the male, and crowd's sickness rate is about 3 ﹪, modern medicine equipment can't definitely be diagnosed, its cause of disease and pathogeny it be unclear that, and have found at present to change with the relevant a series of Physiology and biochemistries that show effect, and think vasomotor dysfunction disease due to this a kind of electrolyte metabolism imbalance and the endocrine regulation.Medical science thinks, primary disease be human righteousness's weakness, wind, expectorant, the stasis of blood, the result of multi-pathogenesis.End when sending out during its headache, delay is difficult.The cause of disease migraine of intractable headache, trigeminal neuralgia, nervous headache and nasopharyngeal carcinoma etc.Intractable headache has following characteristics: 1, significantly occupation tendency, be the personnel that are engaged in the work occupation of bowing for a long time mostly, as the crowd of printing, weaving, clerk, computer industry, tailor, teacher, student and hobby such as like knitting a sweater, playing Mah-Jong.2, brain, injury of head history person are arranged, the companion feels sick during outbreak, vomiting, dizzy, head tear sense.3, be subject to Changes in weather, menstrual cycle, emotion changes, the influence of drinking.4, pillow rear portion fiber crops are expanded, and Wry Neck, head are worn the steel helmet sense, and preceding metopodynia, temple pain, eyelid are heavy, and it is poor to sleep.At present, analgesic drug product can not be effective on the market, can only the respite symptom, and curative effect is low, and therapeutic effect is undesirable, and therefore, the improvement on the medicine of treatment intractable headache is a problem of needing solution at present badly.
Summary of the invention
At above-mentioned situation, for solving the defective of prior art, the present invention's purpose just provides a kind of Chinese medicine compound for the treatment of intractable headache, can effectively solve the medication problem of treatment intractable headache.
The technical scheme that the present invention solves is, by following weight meter: Rhizoma Chuanxiong 20-30g, Radix Angelicae Dahuricae 10-15g, Rhizoma Cyperi (processed) 6-10g, Radix Paeoniae Alba 20-30g, Rhizoma Gastrodiae 10-15g, Bombyx Batryticatus 10-15g, Radix Angelicae Sinensis 10-15g, Herba Asari 5-10g, Radix Saposhnikoviae 6-10g and Pheretima 6-10g make, wherein, and earlier with Rhizoma Chuanxiong, the Radix Angelicae Dahuricae, Rhizoma Cyperi (processed), the Radix Paeoniae Alba, Rhizoma Gastrodiae, Bombyx Batryticatus, Radix Angelicae Sinensis, Herba Asari, Radix Saposhnikoviae and Pheretima were soaked in water 30 minutes, add Rhizoma Chuanxiong, the Radix Angelicae Dahuricae, Rhizoma Cyperi (processed), the Radix Paeoniae Alba, Rhizoma Gastrodiae, Bombyx Batryticatus, Radix Angelicae Sinensis, Herba Asari, Radix Saposhnikoviae, the water of Pheretima 4-6 times weight, boil with high heat earlier, reuse slow fire boiling 25-35 minute is filtered, win time filtrate, filtering residue adds Rhizoma Chuanxiong again, the Radix Angelicae Dahuricae, Rhizoma Cyperi (processed), the Radix Paeoniae Alba, Rhizoma Gastrodiae, Bombyx Batryticatus, Radix Angelicae Sinensis, Herba Asari, Radix Saposhnikoviae, the water of 3 times of weight of Pheretima, intense fire boils, reuse slow fire boiling 25-35 minute, filter, get filtrate for the second time, merge filtrate twice, mixing promptly.
Drug safety of the present invention has no side effect, and is effective, can be effective to treat intractable headache, is the innovation on the intractable headache medicine.
The specific embodiment
Below in conjunction with embodiment the specific embodiment of the present invention is described in further detail.
Embodiment 1
By following weight meter: Rhizoma Chuanxiong 20g, Radix Angelicae Dahuricae 10g, Rhizoma Cyperi (processed) 6g, Radix Paeoniae Alba 20g, Rhizoma Gastrodiae 10g, Bombyx Batryticatus 10g, Radix Angelicae Sinensis 10g, Herba Asari 5g, Radix Saposhnikoviae 6g and Pheretima 6g make, wherein, earlier with Rhizoma Chuanxiong, the Radix Angelicae Dahuricae, Rhizoma Cyperi (processed), the Radix Paeoniae Alba, Rhizoma Gastrodiae, Bombyx Batryticatus, Radix Angelicae Sinensis, Herba Asari, Radix Saposhnikoviae and Pheretima were soaked in water 30 minutes, added Rhizoma Chuanxiong, the Radix Angelicae Dahuricae, Rhizoma Cyperi (processed), the Radix Paeoniae Alba, Rhizoma Gastrodiae, Bombyx Batryticatus, Radix Angelicae Sinensis, Herba Asari, Radix Saposhnikoviae, the water of 4 times of weight of Pheretima boils earlier with high heat, reuse slow fire boiling 25 minutes, filter, time filtrate of winning, filtering residue adds Rhizoma Chuanxiong again, the Radix Angelicae Dahuricae, Rhizoma Cyperi (processed), the Radix Paeoniae Alba, Rhizoma Gastrodiae, Bombyx Batryticatus, Radix Angelicae Sinensis, Herba Asari, Radix Saposhnikoviae, the water of 3 times of weight of Pheretima, intense fire boils, reuse slow fire boiling 25 minutes is filtered, and gets filtrate for the second time, merge filtrate twice, mixing promptly.
Embodiment 2
By following weight meter: Rhizoma Chuanxiong 25g, Radix Angelicae Dahuricae 13g, Rhizoma Cyperi (processed) 8g, Radix Paeoniae Alba 23g, Rhizoma Gastrodiae 13g, Bombyx Batryticatus 13g, Radix Angelicae Sinensis 13g, Herba Asari 8g, Radix Saposhnikoviae 8g and Pheretima 8g make, wherein, earlier with Rhizoma Chuanxiong, the Radix Angelicae Dahuricae, Rhizoma Cyperi (processed), the Radix Paeoniae Alba, Rhizoma Gastrodiae, Bombyx Batryticatus, Radix Angelicae Sinensis, Herba Asari, Radix Saposhnikoviae and Pheretima were soaked in water 30 minutes, added Rhizoma Chuanxiong, the Radix Angelicae Dahuricae, Rhizoma Cyperi (processed), the Radix Paeoniae Alba, Rhizoma Gastrodiae, Bombyx Batryticatus, Radix Angelicae Sinensis, Herba Asari, Radix Saposhnikoviae, the water of 5 times of weight of Pheretima boils earlier with high heat, reuse slow fire boiling 30 minutes, filter, time filtrate of winning, filtering residue adds Rhizoma Chuanxiong again, the Radix Angelicae Dahuricae, Rhizoma Cyperi (processed), the Radix Paeoniae Alba, Rhizoma Gastrodiae, Bombyx Batryticatus, Radix Angelicae Sinensis, Herba Asari, Radix Saposhnikoviae, the water of 3 times of weight of Pheretima, intense fire boils, reuse slow fire boiling 30 minutes is filtered, and gets filtrate for the second time, merge filtrate twice, mixing promptly.
Embodiment 3
By following weight meter: Rhizoma Chuanxiong 30g, Radix Angelicae Dahuricae 15g, Rhizoma Cyperi (processed) 10g, Radix Paeoniae Alba 30g, Rhizoma Gastrodiae 15g, Bombyx Batryticatus 15g, Radix Angelicae Sinensis 15g, Herba Asari 10g, Radix Saposhnikoviae 10g and Pheretima 10g make, wherein, earlier with Rhizoma Chuanxiong, the Radix Angelicae Dahuricae, Rhizoma Cyperi (processed), the Radix Paeoniae Alba, Rhizoma Gastrodiae, Bombyx Batryticatus, Radix Angelicae Sinensis, Herba Asari, Radix Saposhnikoviae and Pheretima were soaked in water 30 minutes, added Rhizoma Chuanxiong, the Radix Angelicae Dahuricae, Rhizoma Cyperi (processed), the Radix Paeoniae Alba, Rhizoma Gastrodiae, Bombyx Batryticatus, Radix Angelicae Sinensis, Herba Asari, Radix Saposhnikoviae, the water of 6 times of weight of Pheretima boils earlier with high heat, reuse slow fire boiling 35 minutes, filter, time filtrate of winning, filtering residue adds Rhizoma Chuanxiong again, the Radix Angelicae Dahuricae, Rhizoma Cyperi (processed), the Radix Paeoniae Alba, Rhizoma Gastrodiae, Bombyx Batryticatus, Radix Angelicae Sinensis, Herba Asari, Radix Saposhnikoviae, the water of 3 times of weight of Pheretima, intense fire boils, reuse slow fire boiling 35 minutes is filtered, and gets filtrate for the second time, merge filtrate twice, mixing promptly.
Embodiment 4
By following weight meter: Rhizoma Chuanxiong 21-24g, Radix Angelicae Dahuricae 10.5-12.5g, Rhizoma Cyperi (processed) 6.5-7.5g, Radix Paeoniae Alba 21-24g, Rhizoma Gastrodiae 10.5-12.5g, Bombyx Batryticatus 10.5-12.5g, Radix Angelicae Sinensis 10.5-12.5g, Herba Asari 5.5-7.5g, Radix Saposhnikoviae 6.5-7.5g and Pheretima 6.5-7.5g make, wherein, earlier with Rhizoma Chuanxiong, the Radix Angelicae Dahuricae, Rhizoma Cyperi (processed), the Radix Paeoniae Alba, Rhizoma Gastrodiae, Bombyx Batryticatus, Radix Angelicae Sinensis, Herba Asari, Radix Saposhnikoviae and Pheretima were soaked in water 30 minutes, added Rhizoma Chuanxiong, the Radix Angelicae Dahuricae, Rhizoma Cyperi (processed), the Radix Paeoniae Alba, Rhizoma Gastrodiae, Bombyx Batryticatus, Radix Angelicae Sinensis, Herba Asari, Radix Saposhnikoviae, the water of Pheretima 4-6 times weight boils earlier with high heat, reuse slow fire boiling 25-35 minute, filter, time filtrate of winning, filtering residue adds Rhizoma Chuanxiong again, the Radix Angelicae Dahuricae, Rhizoma Cyperi (processed), the Radix Paeoniae Alba, Rhizoma Gastrodiae, Bombyx Batryticatus, Radix Angelicae Sinensis, Herba Asari, Radix Saposhnikoviae, the water of 3 times of weight of Pheretima, intense fire boils, reuse slow fire boiling 25-35 minute is filtered, and gets filtrate for the second time, merge filtrate twice, mixing promptly.
Embodiment 5
By following weight meter: Rhizoma Chuanxiong 26-29g, Radix Angelicae Dahuricae 13.5-14.5g, Rhizoma Cyperi (processed) 8.5-9.5g, Radix Paeoniae Alba 26-29g, Rhizoma Gastrodiae 13.5-14.5g, Bombyx Batryticatus 13.5-14.5g, Radix Angelicae Sinensis 13.5-14.5g, Herba Asari 8.5-9.5g, Radix Saposhnikoviae 8.5-9.5g and Pheretima 8.5-9.5g make, wherein, earlier with Rhizoma Chuanxiong, the Radix Angelicae Dahuricae, Rhizoma Cyperi (processed), the Radix Paeoniae Alba, Rhizoma Gastrodiae, Bombyx Batryticatus, Radix Angelicae Sinensis, Herba Asari, Radix Saposhnikoviae and Pheretima were soaked in water 30 minutes, added Rhizoma Chuanxiong, the Radix Angelicae Dahuricae, Rhizoma Cyperi (processed), the Radix Paeoniae Alba, Rhizoma Gastrodiae, Bombyx Batryticatus, Radix Angelicae Sinensis, Herba Asari, Radix Saposhnikoviae, the water of Pheretima 4-6 times weight boils earlier with high heat, reuse slow fire boiling 25-35 minute, filter, time filtrate of winning, filtering residue adds Rhizoma Chuanxiong again, the Radix Angelicae Dahuricae, Rhizoma Cyperi (processed), the Radix Paeoniae Alba, Rhizoma Gastrodiae, Bombyx Batryticatus, Radix Angelicae Sinensis, Herba Asari, Radix Saposhnikoviae, the water of 3 times of weight of Pheretima, intense fire boils, reuse slow fire boiling 25-35 minute is filtered, and gets filtrate for the second time, merge filtrate twice, mixing promptly.
The present invention it is to be noted that the technological core that the present invention asks for protection is prescription (Chinese medicine compound), every decoction of making according to this Chinese medicine compound, and pill, powder or capsule all belong to the scope that the present invention asks for protection.
In said medicine, wherein:
Rhizoma Chuanxiong: effect: blood circulation promoting and blood stasis dispelling; Activating QI to alleviate the depression; Wind-expelling pain-stopping.Cure mainly: medicine first choice of the treatment headache.Menoxenia; The amenorrhea dysmenorrhea; Puerperal, the stasis of blood stagnated raw meat bitterly; The lump in the abdomen lump; Pain in chest and hypochondrium; It is dizzy to have a headache; Anemofrigid-damp arthralgia; Traumatic injury; Ulcer sores.
The Radix Angelicae Dahuricae: suffering, temperature.Attending effectiveness: expelling wind and removing dampness; Logical surreptitiously pain relieving; Detumescence and apocenosis.Main headache due to common cold; Supraorbital bone pain; Toothache; Nasal obstruction; Nasal sinusitis; The domination of damp pathogen chronic diarrhea; The women leucorrhea; Ulcer sores; Venom.Be used for headache due to common cold, supraorbital bone pain, nasal obstruction, nasal sinusitis, toothache, leucorrhea, skin infection swells and ache.Function: the cold expelling that induces sweat, wind-expelling pain-stopping, clearing the nasal passage, dampness leukorrhagia stopping, detumescence and apocenosis.Control headache, supraorbital bone pain, toothache, nasal sinusitis, cold-damp stomachache, hemorrhoidal hamorrhage anal fistula, leucorrhea with red and white discharge, ulcer sores, skin pruritus due to dryness, scabies.
Rhizoma Cyperi (processed): acrid in the mouth, little hardship, sweet, property is flat.Effect: depressed liver-energy dispersing and QI regulating, menstruction regulating and pain relieving.Cure mainly irritability stasis, hypochondriac pain uncomfortable in chest, gastropathy, stomachache; And menoxenia, diseases such as dysmenorrhea.
The Radix Paeoniae Alba: cool in nature, bitter in the mouth acid is slightly cold, and has the easing the affected liver of enriching blood, suppressing the hyperactive liver pain relieving.Yin fluid astringing is received effects such as antiperspirant, is applicable to fever due to yin deficiency, menoxenia, the breast abdomen pain over the hypochondriac region, extremity contraction suddenly, diseases such as dysentery stomachache, spontaneous sweating, metrorrhagia, leukorrhagia.Rhizoma Gastrodiae:
Bombyx Batryticatus: acrid in the mouth, salty, property is flat, has expelling wind to relieve convulsion, dissipating phlegm and resolving masses, the effect of heat-clearing and toxic substances removing dampness clinically is used to control heat syndrome cough more, and phlegm dyspnea is spitted blood, collapses, band, traumatic injury, rheumatalgia, sore etc. are salty, hot, flat.Return liver, lung, stomach warp.Expelling wind for relieving convulsion, dissipating phlegm and resolving masses.Be used for convulsion with spasms, laryngopharynx swelling and pain, submandibular lymph nodes inflammation, facial paralysis, skin pruritus.
Radix Angelicae Sinensis: sweet in the mouth; Hot; Bitter; Warm in nature, enrich blood; Invigorate blood circulation; Menstruction regulating and pain relieving; Moisturize laxation, all cards of blood deficiency; Menoxenia; Amenorrhea; Dysmenorrhea; The lump in the abdomen knot is poly-; Metrorrhagia; Asthenia cold abdominalgia; Flaccidity syndrome and arthralgia syndrome; Numbness of the skin; The dryness of the intestine dyschezia; Heavy after the bloody dysentery; Ulcer sores; Injury from falling down.
Herba Asari: cure mainly: dispel the wind, cold expelling, row water is had one's ideas straightened out.Control air-cooled headache, nasal sinusitis, toothache, phlegm retention cough with dyspnea, rheumatic arthralgia.
Radix Saposhnikoviae: acrid in the mouth; Sweet; Slightly warm in nature.Effect: expelling pathogenic wind from the body surface, removing dampness to relieve pain, spasmolytic, antipruritic.Cure mainly: affection of exogenous wind-cold; The headache general pain; Rheumatic arthralgia; Joint is ached; Stomachache is had loose bowels; Discharging fresh blood stool; Tetanus; The rubella pruritus; Skin infection from the beginning of.
Pheretima: salty-cold.Heat clearing away, spasmolytic, diuresis, detoxifcation.Calentura mania and irritation, infantile convulsion, cough with asthma, headache conjunctival congestion, laryngopharynx swelling and pain, urinary obstruction, Fengshi Guanjie pain, diseases such as hemiplegia.External is coated with diseases such as erysipelas, dermatitis rhus.
Effective combination of said medicine is supported mutually, and has the effect of phlegm reduction of blood circulation promoting, calming wind and dredging collateral, wind-expelling pain-stopping through the science preparation, and environment in the conditioning human body strengthens autoimmune function.Simple and easy to use, short treating period, instant effect, drug safety.Be effective to treat intractable headache, and obtained satisfied effect through test.
Relevant experimental data is as follows:
1 clinical data
1.1 the case data is chosen from January, 2008 to 2,011 second out-patient of encephalopathy section of Affiliated Hospital of year December Henan college of traditional Chinese medicine, 100 examples, is divided into each 50 example of treatment group and matched group at random.Wherein 50 examples are organized in treatment, male wherein, 22 examples, women's 28 examples; Age 18-54 year, 32.7 ± 9.8 years old mean age; The course of disease 3 months～15 years, average course of disease 6.8 ± 2.4 years; Matched group 50 examples, male's 20 examples wherein, women's 30 examples, 20～54 years old age, 33.6 ± 9.4 years old mean age, the course of disease 3 months～14 years, average course of disease 6.6 ± 2.8 years.Two groups of patients physical data such as sex, age, the course of disease by statistics credit analyse there was no significant difference (
P0.05), have comparability.
Diagnostic criteriaThe diagnostic criteria of the intractable headache of tcm diagnosis standard reference encephalopathy academic board of national association of traditional Chinese medicine formulation in 1990
[1]Clinical manifestation: headache is outbreak repeatedly〉6 months, the headache position is many on head one side volume temporo, forehead, top, mountain peak, or a left side or the right side toss about in bed outbreak, or is full headache.The character of headache mostly is jumping pain, twinge, distending pain, dusk pain, dull pain, or headache as split etc.Sustainable several minutes of the each outbreak of headache, a few hours, a couple of days, lasting several weeks of person is arranged also.
Include standard in:1. meet diagnostic criteria; 2. the age was at 18～65 years old; 3. agree to participate in the experiment the signature Informed Consent Form.
Exclusion standard:1. the age is below 18 one full year of life or above person of 65 one full year of life; 2. trimester of pregnancy, women breast-feeding their children; 3. be associated with serious primary disease person such as cardiovascular, lung, liver, kidney and hemopoietic system; 4. intracranial organic disease and diseases of the five sense organs.
Therapeutic Method
2.1 the matched group patient all gives XIBILING JIAONANG (another name flunarizine hydrochloride, Xian-Janssen Pharmaceutical Ltd. produces, the accurate word H10930003 of traditional Chinese medicines, every 5mg) treatment, clothes 10mg before sleeping every night.Be 2 weeks the course of treatment, viewing duration forbidding other drug.
2.2 the treatment group is taken Chinese medicine of the present invention.Morning and evening service once, each 200-300ml, continuous 14 days.Avoid strong tea, coffee, pungent stimulation food during the treatment.Two groups of curative effects are observed in the treatment back.
Curative effect determinate standard" new Chinese medicine clinical research guideline " according to Ministry of Health of the People's Republic of China's issue worked out.Cure: treating does not have recurrence in back 1 year; Produce effects: treatment back symptom disappears substantially, though or have the headache symptom lighter, do not influence operate as normal and life; Effectively: treatment back attack times obviously reduces, and symptom more still can be stood; Invalid: treatment back symptom no change.
4 statistical method total datas are all through the SPSS10.0 software processes, and measurement data adopts the t check, and enumeration data adopts χ
2Check, ranked data are checked with Ridit.
The result
Two groups of patient's clinical efficacies relatively see Table 1.
Table 1 liang group patient curative effect relatively
| Group | Cure | Produce effects | Effectively | Invalid | Total effective rate |
| Treatment group (50) | 22 | 18 | 5 | 5 | 90% |
| Matched group (50) | 12 | 21 | 5 | 12 | 76% |
As seen from the above table, the treatment group is totally 50 examples: cure 22 examples, and produce effects 18 examples, effective 5 examples, invalid 5 examples, effective percentage is 90%; Matched group is totally 50 examples: cure 12 examples, and produce effects 21 examples, effective 5 examples, invalid 12 examples, total effective rate is 76%.Two groups of curative effects are relatively analyzed μ=2.26, P=0.024＜0.05, difference statistical significance through Ridit.
5 discuss
Intractable headache mainly refers to vascular headache, nervous headache, the muscle tonus headache of modern medicine.This sick sickness rate is higher, and symptom is outstanding, and outbreak is frequent, brings huge misery to the patient, has a strong impact on crowd's quality of life.
5.1 the cause of disease of etiology and pathogenesis and rule of treatment intractable headache, motherland's medical science is thought: head is " confluence of all yang-channels, the mansion of clear sun ", and brain is gathered by bone marrow, the blood of all the five internal organs elite is annotated in head on all, attacks so the heresy of all six climate exopathogens is outer, top, last criminal top, pathogen is delaied, and checks sun clearly; Always be obstructed at last, due to QI-blood circulation is not smooth by the head meridians.Or all diseases of internal injury, cause QI and blood disorderly contrary, stasis of blood resistance meridians, brain is become homeless foster, all can have a headache.Pathogen usually intruding into collateral in protracted disease forms congestion, stagnation of blood stasis, and the wet operation of water is not normal, stops the poly-expectorant that is, phlegm stagnating in meridian, QI and blood is not smooth, gives birth in the blood stasis, and phlegm and blood stasis forms the important pathogenesis of primary disease.The rule of treatment is with eleminating phlegm and freeing channels, opening the orifice and activating blood circulation, and the wind pain relieving of loosing is main.
5.2 pharmaceutical analysis wind syndrome of head soup is made up of Rhizoma Chuanxiong, Radix Angelicae Sinensis, the Radix Paeoniae Alba, the Radix Angelicae Dahuricae, Rhizoma Cyperi (processed), Rhizoma Gastrodiae, Bombyx Batryticatus, Herba Asari, Radix Saposhnikoviae, Pheretima.Rhizoma Chuanxiong is the gas medicine in the blood in the side, and the up head of energy assigns the sea of blood, and is current all through QI and blood, is the key medicine of treatment headache, positive so-called " control wind and control blood earlier, the blood sector-style is gone out certainly "; Radix Angelicae Sinensis, Radix Paeoniae Alba nourshing blood and promoting blood circulation, antalgic; Relieving rheumatism and cold, invigorating blood circulation and stopping pains for the Radix Angelicae Dahuricae; The Rhizoma Cyperi (processed) resolving depression of regulating the flow of vital energy, menstruction regulating and pain relieving; The pain relieving of Rhizoma Gastrodiae suppressing the hyperactive liver to relieve the wind syndrome; Bombyx Batryticatus endogenous wind stopping collateral dredging priming is up and be minister; The Herba Asari antalgic, drying dampness to eliminate phlegm; Radix Saposhnikoviae is for controlling the key medicine of wind; Pheretima is apt to the expel wind to dredge collateral pain relieving.All medicines share, and have the merit of phlegm reduction of blood circulation promoting, calming wind and dredging collateral, wind-expelling pain-stopping.
Modern study shows that Rhizoma Chuanxiong has effects such as blood vessel dilating, spasmolytic, antithrombotic formation; Radix Angelicae Sinensis can significantly promote the body hemopoietic function, rising erythrocyte, leukocyte and content of hemoglobin, and enhancing human body immunity power can blood vessel dilating, and effect such as bring high blood pressure down.
5.3 clinical efficacy treatment group is totally 50 examples: cure 22 examples, produce effects 18 examples, effective 5 examples, invalid 5 examples, effective percentage is 90%; Matched group is totally 50 examples: cure 12 examples, and produce effects 21 examples, effective 5 examples, invalid 12 examples, total effective rate is 76%.Two groups of curative effects are relatively analyzed μ=2.26, P=0.024＜0.05, difference statistical significance through Ridit.The treatment group matched group that is better than evident in efficacy is described.
Conclusion
By the clinical research of above treatment intractable headache, draw to draw a conclusion:
1. phlegm and blood stasis is the main pathogenesis of intractable headache.Eleminating phlegm and freeing channels, opening the orifice and activating blood circulation, the wind pain relieving of loosing is the base therapy method of intractable headache.It is evident in efficacy that the present invention treats intractable insomnia.
2. all obviously improve after the treatment of intractable headache patient's primary symptom, the present invention can obviously improve curative effect.
Claims (6)
1. Chinese medicine for the treatment of intractable headache, it is characterized in that, by following weight meter: Rhizoma Chuanxiong 20-30g, Radix Angelicae Dahuricae 10-15g, Rhizoma Cyperi (processed) 6-10g, Radix Paeoniae Alba 20-30g, Rhizoma Gastrodiae 10-15g, Bombyx Batryticatus 10-15g, Radix Angelicae Sinensis 10-15g, Herba Asari 5-10g, Radix Saposhnikoviae 6-10g and Pheretima 6-10g make, wherein, earlier with Rhizoma Chuanxiong, the Radix Angelicae Dahuricae, Rhizoma Cyperi (processed), the Radix Paeoniae Alba, Rhizoma Gastrodiae, Bombyx Batryticatus, Radix Angelicae Sinensis, Herba Asari, Radix Saposhnikoviae and Pheretima were soaked in water 30 minutes, added Rhizoma Chuanxiong, the Radix Angelicae Dahuricae, Rhizoma Cyperi (processed), the Radix Paeoniae Alba, Rhizoma Gastrodiae, Bombyx Batryticatus, Radix Angelicae Sinensis, Herba Asari, Radix Saposhnikoviae, the water of Pheretima 4-6 times weight boils earlier with high heat, reuse slow fire boiling 25-35 minute, filter, time filtrate of winning, filtering residue adds Rhizoma Chuanxiong again, the Radix Angelicae Dahuricae, Rhizoma Cyperi (processed), the Radix Paeoniae Alba, Rhizoma Gastrodiae, Bombyx Batryticatus, Radix Angelicae Sinensis, Herba Asari, Radix Saposhnikoviae, the water of 3 times of weight of Pheretima, intense fire boils, reuse slow fire boiling 25-35 minute is filtered, and gets filtrate for the second time, merge filtrate twice, mixing promptly.
2. the Chinese medicine of treatment intractable headache according to claim 1, it is characterized in that, by following weight meter: Rhizoma Chuanxiong 20g, Radix Angelicae Dahuricae 10g, Rhizoma Cyperi (processed) 6g, Radix Paeoniae Alba 20g, Rhizoma Gastrodiae 10g, Bombyx Batryticatus 10g, Radix Angelicae Sinensis 10g, Herba Asari 5g, Radix Saposhnikoviae 6g and Pheretima 6g make, wherein, earlier with Rhizoma Chuanxiong, the Radix Angelicae Dahuricae, Rhizoma Cyperi (processed), the Radix Paeoniae Alba, Rhizoma Gastrodiae, Bombyx Batryticatus, Radix Angelicae Sinensis, Herba Asari, Radix Saposhnikoviae and Pheretima were soaked in water 30 minutes, added Rhizoma Chuanxiong, the Radix Angelicae Dahuricae, Rhizoma Cyperi (processed), the Radix Paeoniae Alba, Rhizoma Gastrodiae, Bombyx Batryticatus, Radix Angelicae Sinensis, Herba Asari, Radix Saposhnikoviae, the water of 4 times of weight of Pheretima boils earlier with high heat, reuse slow fire boiling 25 minutes, filter, time filtrate of winning, filtering residue adds Rhizoma Chuanxiong again, the Radix Angelicae Dahuricae, Rhizoma Cyperi (processed), the Radix Paeoniae Alba, Rhizoma Gastrodiae, Bombyx Batryticatus, Radix Angelicae Sinensis, Herba Asari, Radix Saposhnikoviae, the water of 3 times of weight of Pheretima, intense fire boils, reuse slow fire boiling 25 minutes is filtered, and gets filtrate for the second time, merge filtrate twice, mixing promptly.
3. the Chinese medicine of treatment intractable headache according to claim 1, it is characterized in that, by following weight meter: Rhizoma Chuanxiong 25g, Radix Angelicae Dahuricae 13g, Rhizoma Cyperi (processed) 8g, Radix Paeoniae Alba 23g, Rhizoma Gastrodiae 13g, Bombyx Batryticatus 13g, Radix Angelicae Sinensis 13g, Herba Asari 8g, Radix Saposhnikoviae 8g and Pheretima 8g make, wherein, earlier with Rhizoma Chuanxiong, the Radix Angelicae Dahuricae, Rhizoma Cyperi (processed), the Radix Paeoniae Alba, Rhizoma Gastrodiae, Bombyx Batryticatus, Radix Angelicae Sinensis, Herba Asari, Radix Saposhnikoviae and Pheretima were soaked in water 30 minutes, added Rhizoma Chuanxiong, the Radix Angelicae Dahuricae, Rhizoma Cyperi (processed), the Radix Paeoniae Alba, Rhizoma Gastrodiae, Bombyx Batryticatus, Radix Angelicae Sinensis, Herba Asari, Radix Saposhnikoviae, the water of 5 times of weight of Pheretima boils earlier with high heat, reuse slow fire boiling 30 minutes, filter, time filtrate of winning, filtering residue adds Rhizoma Chuanxiong again, the Radix Angelicae Dahuricae, Rhizoma Cyperi (processed), the Radix Paeoniae Alba, Rhizoma Gastrodiae, Bombyx Batryticatus, Radix Angelicae Sinensis, Herba Asari, Radix Saposhnikoviae, the water of 3 times of weight of Pheretima, intense fire boils, reuse slow fire boiling 30 minutes is filtered, and gets filtrate for the second time, merge filtrate twice, mixing promptly.
4. the Chinese medicine of treatment intractable headache according to claim 1, it is characterized in that, by following weight meter: Rhizoma Chuanxiong 30g, Radix Angelicae Dahuricae 15g, Rhizoma Cyperi (processed) 10g, Radix Paeoniae Alba 30g, Rhizoma Gastrodiae 15g, Bombyx Batryticatus 15g, Radix Angelicae Sinensis 15g, Herba Asari 10g, Radix Saposhnikoviae 10g and Pheretima 10g make, wherein, earlier with Rhizoma Chuanxiong, the Radix Angelicae Dahuricae, Rhizoma Cyperi (processed), the Radix Paeoniae Alba, Rhizoma Gastrodiae, Bombyx Batryticatus, Radix Angelicae Sinensis, Herba Asari, Radix Saposhnikoviae and Pheretima were soaked in water 30 minutes, added Rhizoma Chuanxiong, the Radix Angelicae Dahuricae, Rhizoma Cyperi (processed), the Radix Paeoniae Alba, Rhizoma Gastrodiae, Bombyx Batryticatus, Radix Angelicae Sinensis, Herba Asari, Radix Saposhnikoviae, the water of 6 times of weight of Pheretima boils earlier with high heat, reuse slow fire boiling 35 minutes, filter, time filtrate of winning, filtering residue adds Rhizoma Chuanxiong again, the Radix Angelicae Dahuricae, Rhizoma Cyperi (processed), the Radix Paeoniae Alba, Rhizoma Gastrodiae, Bombyx Batryticatus, Radix Angelicae Sinensis, Herba Asari, Radix Saposhnikoviae, the water of 3 times of weight of Pheretima, intense fire boils, reuse slow fire boiling 35 minutes is filtered, and gets filtrate for the second time, merge filtrate twice, mixing promptly.
5. the Chinese medicine of treatment intractable headache according to claim 1, it is characterized in that, by following weight meter: Rhizoma Chuanxiong 21-24g, Radix Angelicae Dahuricae 10.5-12.5g, Rhizoma Cyperi (processed) 6.5-7.5g, Radix Paeoniae Alba 21-24g, Rhizoma Gastrodiae 10.5-12.5g, Bombyx Batryticatus 10.5-12.5g, Radix Angelicae Sinensis 10.5-12.5g, Herba Asari 5.5-7.5g, Radix Saposhnikoviae 6.5-7.5g and Pheretima 6.5-7.5g make, wherein, earlier with Rhizoma Chuanxiong, the Radix Angelicae Dahuricae, Rhizoma Cyperi (processed), the Radix Paeoniae Alba, Rhizoma Gastrodiae, Bombyx Batryticatus, Radix Angelicae Sinensis, Herba Asari, Radix Saposhnikoviae and Pheretima were soaked in water 30 minutes, added Rhizoma Chuanxiong, the Radix Angelicae Dahuricae, Rhizoma Cyperi (processed), the Radix Paeoniae Alba, Rhizoma Gastrodiae, Bombyx Batryticatus, Radix Angelicae Sinensis, Herba Asari, Radix Saposhnikoviae, the water of Pheretima 4-6 times weight boils earlier with high heat, reuse slow fire boiling 25-35 minute, filter, time filtrate of winning, filtering residue adds Rhizoma Chuanxiong again, the Radix Angelicae Dahuricae, Rhizoma Cyperi (processed), the Radix Paeoniae Alba, Rhizoma Gastrodiae, Bombyx Batryticatus, Radix Angelicae Sinensis, Herba Asari, Radix Saposhnikoviae, the water of 3 times of weight of Pheretima, intense fire boils, reuse slow fire boiling 25-35 minute is filtered, and gets filtrate for the second time, merge filtrate twice, mixing promptly.
6. the Chinese medicine of treatment intractable headache according to claim 1, it is characterized in that, by following weight meter: Rhizoma Chuanxiong 26-29g, Radix Angelicae Dahuricae 13.5-14.5g, Rhizoma Cyperi (processed) 8.5-9.5g, Radix Paeoniae Alba 26-29g, Rhizoma Gastrodiae 13.5-14.5g, Bombyx Batryticatus 13.5-14.5g, Radix Angelicae Sinensis 13.5-14.5g, Herba Asari 8.5-9.5g, Radix Saposhnikoviae 8.5-9.5g and Pheretima 8.5-9.5g make, wherein, earlier with Rhizoma Chuanxiong, the Radix Angelicae Dahuricae, Rhizoma Cyperi (processed), the Radix Paeoniae Alba, Rhizoma Gastrodiae, Bombyx Batryticatus, Radix Angelicae Sinensis, Herba Asari, Radix Saposhnikoviae and Pheretima were soaked in water 30 minutes, added Rhizoma Chuanxiong, the Radix Angelicae Dahuricae, Rhizoma Cyperi (processed), the Radix Paeoniae Alba, Rhizoma Gastrodiae, Bombyx Batryticatus, Radix Angelicae Sinensis, Herba Asari, Radix Saposhnikoviae, the water of Pheretima 4-6 times weight boils earlier with high heat, reuse slow fire boiling 25-35 minute, filter, time filtrate of winning, filtering residue adds Rhizoma Chuanxiong again, the Radix Angelicae Dahuricae, Rhizoma Cyperi (processed), the Radix Paeoniae Alba, Rhizoma Gastrodiae, Bombyx Batryticatus, Radix Angelicae Sinensis, Herba Asari, Radix Saposhnikoviae, the water of 3 times of weight of Pheretima, intense fire boils, reuse slow fire boiling 25-35 minute is filtered, and gets filtrate for the second time, merge filtrate twice, mixing promptly.
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Cited By (3)
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| CN104826067A (en) * | 2015-05-20 | 2015-08-12 | 申洪恩 | Medicine for treating intractable headache and production method thereof |
| CN104826075A (en) * | 2015-05-26 | 2015-08-12 | 河南中医学院 | Traditional Chinese medicine for treating stubborn headache |
| CN111544507A (en) * | 2020-06-24 | 2020-08-18 | 河南中医药大学 | Compound traditional Chinese medicine for treating blood stasis headache |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104826067A (en) * | 2015-05-20 | 2015-08-12 | 申洪恩 | Medicine for treating intractable headache and production method thereof |
| CN104826075A (en) * | 2015-05-26 | 2015-08-12 | 河南中医学院 | Traditional Chinese medicine for treating stubborn headache |
| CN104826075B (en) * | 2015-05-26 | 2018-04-06 | 河南中医学院 | A kind of Chinese medicine for treating intractable headache |
| CN111544507A (en) * | 2020-06-24 | 2020-08-18 | 河南中医药大学 | Compound traditional Chinese medicine for treating blood stasis headache |
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