CN108686044B - Liver-protecting agent for cultivating eriocheir sinensis and preparation method thereof - Google Patents
Liver-protecting agent for cultivating eriocheir sinensis and preparation method thereof Download PDFInfo
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- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/539—Scutellaria (skullcap)
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
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- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/80—Scrophulariaceae (Figwort family)
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
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- A61K2236/50—Methods involving additional extraction steps
- A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
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Abstract
The invention relates to a eriocheir sinensis culture liver agent and a preparation method thereof, belonging to the technical field of aquatic feed production. It mainly comprises semen Cassiae, herba Scutellariae Barbatae, cortex moutan, cortex Albizziae, semen Platycladi, Eucommiae cortex, Poria, lignum Pini nodi, radix Paeoniae Rubra, and radix rehmanniae. The liver-protecting agent for aquaculture is obtained by crushing, soaking, decocting, filtering, concentrating and packaging. The invention is added into feed for use when the immunity of aquaculture animals is low. The components are Chinese herbal medicine components, so that the Chinese herbal medicine composition has the advantages of small toxicity, small side effect and the like, has the functions of protecting liver and gallbladder, tranquilizing and allaying excitement, enhancing immunity, resisting stress and the like, and is an efficient and environment-friendly liver-protecting agent for cultivating the eriocheir sinensis.
Description
Technical Field
The invention belongs to the technical field of animal feed production, and particularly relates to a liver-protecting agent for cultivating eriocheir sinensis and a preparation method thereof.
Background
Eriocheir sinensis (A. sinensis)Eriocheir sinensis) Commonly known as river crab, belonging to Arthropoda, Crustacea and Eriocheir sinensis (Eriocheir). The fish meat is tender and delicious, is regarded as a precious aquatic product, and is deeply favored by consumers. The artificial breeding of the eriocheir sinensis is explored from the 70 th of the 20 th century, and the eriocheir sinensis becomes a new leading and supporting variety of the famous and excellent fresh water in China nowadays and plays an important role in promoting the continuous and healthy development of the fresh water breeding production in China.
The liver and the pancreas are important tissues of the river crab, participate in a plurality of functions of digestion, storage, secretion of growth promoting substances, detoxification, immunity, nutrient absorption and the like in vivo, and have great significance for the normal growth and development of the river crab. In recent years, the hepatopancreas of the river crabs are damaged and even die due to environmental pollution, improper culture management and the like. Therefore, in river crab farming, the protection of the hepatopancreas is extremely important. At present, researches on preparations for protecting the liver of the river crabs are few, and meanwhile, the medicine effect of each component is relatively single, so that the comprehensive protection and the improvement of the liver and pancreas functions of the river crabs cannot be realized, and therefore, a strong, comprehensive, environment-friendly, simple, convenient and practical liver protecting agent for cultivating the eriocheir sinensis and a preparation method thereof are urgently needed.
Disclosure of Invention
Aiming at the defects of the existing river crab liver-protecting agent research, the invention aims to develop an efficient and environment-friendly liver-protecting agent for cultivating Chinese mitten crabs, which can comprehensively protect and enhance the liver and pancreas functions of river crabs, and a preparation method thereof. The following technical scheme is adopted:
a liver protecting agent for cultivating Eriocheir sinensis and a preparation method thereof are characterized by comprising 5-11 parts of cassia seed, 4-10 parts of barbed skullcap herb, 3-8 parts of tree peony bark, 2-7 parts of silktree albizzia bark, 2-6 parts of platycladi seed, 3-8 parts of eucommia bark, 2-9 parts of tuckahoe, 2-6 parts of Chinese pine, 3-8 parts of red paeony root, 2-11 parts of radix rehmanniae and 48-55 parts of water.
The invention relates to a liver-protecting agent for cultivating eriocheir sinensis, which comprises the following steps:
A. mixing semen Cassiae, herba Scutellariae Barbatae, cortex moutan, cortex Albizziae, semen Platycladi, Eucommiae cortex, Poria, lignum Pini nodi, radix Paeoniae Rubra, and radix rehmanniae, pulverizing for one time until 95% of the powder passes through a 10-mesh screen;
B. b, soaking the mixture obtained in the step A in water for 50-80 minutes;
C. decocting the mixture with slow fire for 1-1.5 hr, and filtering to obtain filtrate;
D. heating and concentrating the filtrate for 1-1.5 hours until the volume is 1/2 before concentration;
E. after the concentrated solution is cooled, the concentrated solution is packaged and sealed, and the liver-protecting agent for cultivating the eriocheir sinensis is obtained.
The invention has the following beneficial effects:
the invention preferably selects the components of the Chinese herbal medicines, has no toxicity and no harm, has small side effect, has scientific compatibility of the components, has the functions of protecting liver, promoting gallbladder, tranquilizing mind, enhancing immunity, resisting stress and the like, and can comprehensively protect the liver and the pancreas of the river crabs. Meanwhile, the feed attractant is added to enhance the palatability of the river crabs to the feed. Is a fully effective, green and favorite liver-protecting agent for cultivating the eriocheir sinensis, and has simple preparation.
Detailed Description
The invention will be further illustrated with reference to specific examples below:
example 1
A liver protection agent for cultivating Eriocheir sinensis and a preparation method thereof comprise the following raw materials in parts by weight: 8 parts of cassia seed, 7 parts of barbed skullcap herb, 5 parts of tree peony bark, 5 parts of silktree albizzia bark, 3 parts of platycladi seed, 4 parts of eucommia bark, 5 parts of tuckahoe, 4 parts of Chinese pine, 5 parts of red paeony root, 4 parts of rehmannia root and 50 parts of water.
The preparation method of the liver-protecting agent for cultivating the eriocheir sinensis comprises the following steps:
A. mixing semen Cassiae, herba Scutellariae Barbatae, cortex moutan, cortex Albizziae, semen Platycladi, Eucommiae cortex, Poria, lignum Pini nodi, radix Paeoniae Rubra, and radix rehmanniae, pulverizing for one time until 95% of the powder passes through a 10-mesh screen;
B. b, adding water into the mixture obtained in the step A, and soaking for 55 minutes;
C. decocting the mixture with slow fire for 1 hr, and filtering to obtain filtrate;
D. heating and concentrating the filtrate for 1 hour until the volume is 1/2 before concentration;
E. after the concentrated solution is cooled, the concentrated solution is packaged and sealed, and the liver-protecting agent for cultivating the eriocheir sinensis is obtained.
The preferred components of the invention have the following beneficial effects:
cassia seed: also called Cassia occidentalis, Remuzi, etc., which are the mature seeds of Cassia tora or Cassia tora which are leguminous herbaceous plants. Has effects in clearing away liver-fire, invigorating kidney, and improving eyesight. The composition is used as a component for clearing liver fire and protecting liver.
Barbed skullcap herb: also known as hypericum japonicum, moschus brachyotus, etc., are perennial herbs of the genus scutellaria of the family lamiaceae. Has effects in clearing away heat and toxic materials, inhibiting bacteria, and regulating immunity. The health-care tea is used as a component for clearing heat and cooling blood, protecting liver and benefiting gallbladder and enhancing immunity.
Moutan bark: is dried root bark of Paeonia suffruticosa Andr. It is produced in Anhui province, Sichuan province, Henan province, Shandong province, etc. and has the functions of clearing away heat and cooling blood, promoting blood circulation to disperse blood clots, eliminating deficiency heat, nourishing heart, etc. The composition is used as a liver-protecting and heart-nourishing component.
Silktree albizzia bark: is bark of Albizzia julibrissin Durazz of Leguminosae, and has effects of regulating blood, calming heart, and calming five internal organs. The invention is used as a component for tranquilizing and allaying excitement.
Arborvitae seed: is dried mature kernel of Platycladus orientalis of Cupressaceae. Distributed in the south-east, the south-north China, the south-south China, the south-east China, the north China, the west-Shaanxi, Gansu, the southwest-Sichuan, Yunnan, Guizhou, etc. Has effects in nourishing heart, tranquilizing mind, and protecting liver. The composition is used as a component for nourishing the heart and protecting the liver.
Eucommia ulmoides: also called as Bakelite, is a plant of the family Eucommiaceae. Has the effects of tonifying liver and kidney, strengthening tendons and bones, clearing in vivo rubbish, enhancing metabolism of organism cell substances, resisting bacteria in broad spectrum, improving pharmacological action of leucocyte, etc. In the invention, the compound is added as an immunity enhancing component.
Tuckahoe, poria cocos: is dried sclerotium of Poria cocos (Schw.) wolf of Polyporaceae. Is distributed in Hebei, Henan, Shandong, Anhui, Zhejiang, Fujian, Guangdong, Guangxi, Hunan, Hubei, Sichuan, Guizhou, Yunnan, Shanxi, etc. Has effects in invigorating spleen and strengthening body constitution. The composition is used as a component for strengthening spleen and enhancing immunity.
And (3) fragrant pine: also called Nardostachys chinensis, which originates in alpine grassland area or sparse forest with over 3000m and is distributed in Gansu, Qinghai, Sichuan, Yunnan northwest, etc. The cedar is a plant of Valerianaceae. The pharmacological actions mainly include sedation, anti-stress and the like. Meanwhile, the compound has strong rosin-like aroma, and can improve and expand the function exertion range of the food calling factors. In the invention, the composition is used as an anti-stress and food calling component.
Red peony root: is dried root of Ranunculaceae plant radix Paeoniae Rubra or radix Paeoniae Rubra. Distributed in Shaanxi, Gansu, Qinghai, Sichuan and Tibet. Has effects of clearing heat, cooling blood, and resisting stress. It is used as an anti-stress component in the present invention.
Radix rehmanniae: radix rehmanniae, Ye Di Huang, shan Yan Gen, etc., are root tubers of rehmannia glutinosa Libosch of Scrophulariaceae. The perennial herb has the effects of clearing heat and cooling blood, benefiting yin and promoting fluid production and resisting stress. It is used as an anti-stress component in the present invention.
The use effect of the invention is as follows:
is used in aquatic feed producing plant. In the feed production, 30kg of the liver-protecting agent for cultivating the eriocheir sinensis is used per 1 ton of feed. Then used in a local river crab culture pond. The time is 7 months in summer, and before the feed is used, the river crabs have poor food intake, poor vitality and light liver color. After the feed containing the liver-protecting agent is fed, the liver and pancreas of the river crab have good condition and enhanced activity after one week, the river crab is fond of water intake, the food intake is obviously increased, and the physique is enhanced.
Example 2
A liver protection agent for cultivating Eriocheir sinensis and a preparation method thereof comprise the following raw materials in parts by weight: 7 parts of cassia seed, 6 parts of barbed skullcap herb, 7 parts of tree peony bark, 3.5 parts of silktree albizzia bark, 4.5 parts of platycladi seed, 4 parts of eucommia bark, 5 parts of tuckahoe, 4 parts of Chinese pine, 4.5 parts of red paeony root, 5.5 parts of rehmannia root and 49 parts of water.
The preparation method of the liver-protecting agent for aquaculture comprises the following steps:
A. mixing semen Cassiae, herba Scutellariae Barbatae, cortex moutan, cortex Albizziae, semen Platycladi, Eucommiae cortex, Poria, lignum Pini nodi, radix Paeoniae Rubra, and radix rehmanniae, pulverizing for one time until 95% of the powder passes through a 10-mesh screen;
B. b, soaking the mixture obtained in the step A in water for 65 minutes;
C. decocting the mixture with slow fire for 1.2 hr, and filtering to obtain filtrate;
D. heating and concentrating the filtrate for 1 hour until the volume is 1/2 before concentration;
E. after the concentrated solution is cooled, the concentrated solution is packaged and sealed, and the liver-protecting agent for cultivating the eriocheir sinensis is obtained.
The use effect of the invention is as follows:
is used in feed producing factory. In the feed production, 30kg of the liver-protecting agent for cultivating the eriocheir sinensis is used per 1 ton of feed. Then used in a local river crab culture pond. The period of the feed is 8 months in summer, and the river crabs have poor ingestion, poor vitality, atrophy of liver and pancreas and easy death before using the feed. After the feed containing the liver-protecting agent is fed, the hepatopancreas condition of the river crabs is obviously improved after one week, the color is bright, the vitality is enhanced, the river crabs like to eat water, the food intake is obviously increased, and the physique is enhanced.
Claims (2)
1. A liver protecting agent for cultivating Eriocheir sinensis is characterized by comprising 5-11 parts of cassia seed, 4-10 parts of barbed skullcap herb, 3-8 parts of tree peony bark, 2-7 parts of silktree albizzia bark, 2-6 parts of platycladi seed, 3-8 parts of eucommia bark, 2-9 parts of tuckahoe, 2-6 parts of Chinese pine, 3-8 parts of red paeony root, 2-11 parts of radix rehmanniae and 48-55 parts of water;
the preparation method of the liver-protecting agent comprises the following steps:
A. mixing semen Cassiae, herba Scutellariae Barbatae, cortex moutan, cortex Albizziae, semen Platycladi, Eucommiae cortex, Poria, lignum Pini nodi, radix Paeoniae Rubra, and radix rehmanniae, pulverizing for one time until 95% of the powder passes through a 10-mesh screen;
B. b, soaking the mixture obtained in the step A in water for 50-80 minutes;
C. decocting the mixture with slow fire for 1-1.5 hr, and filtering to obtain filtrate;
D. heating and concentrating the filtrate for 1-1.5 hours until the volume is 1/2 before concentration;
E. and after the concentrated solution is cooled, bagging and sealing to obtain the liver-protecting agent for cultivating the eriocheir sinensis.
2. The preparation method of the liver protecting agent for cultivating the eriocheir sinensis as claimed in claim 1, which comprises the following steps:
A. mixing semen Cassiae, herba Scutellariae Barbatae, cortex moutan, cortex Albizziae, semen Platycladi, Eucommiae cortex, Poria, lignum Pini nodi, radix Paeoniae Rubra, and radix rehmanniae, pulverizing for one time until 95% of the powder passes through a 10-mesh screen;
B. b, soaking the mixture obtained in the step A in water for 50-80 minutes;
C. decocting the mixture with slow fire for 1-1.5 hr, and filtering to obtain filtrate;
D. heating and concentrating the filtrate for 1-1.5 hours until the volume is 1/2 before concentration;
E. and after the concentrated solution is cooled, bagging and sealing to obtain the liver-protecting agent for cultivating the eriocheir sinensis.
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Citations (3)
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| CN102988678A (en) * | 2011-09-19 | 2013-03-27 | 天津瑞贝特科技发展有限公司 | Chinese medicinal composition with function of nourishing liver and tonifying kidney, and preparation method thereof |
| CN106614178A (en) * | 2016-11-17 | 2017-05-10 | 南京正源生物技术有限公司 | Composite preparation for preventing and treating water retention disease of river crab and application thereof |
| CN107469013A (en) * | 2017-09-21 | 2017-12-15 | 胡边文 | A kind of medicament and preparation method for being used to prevent and treat aquatic livestock disease in the liver and gallbladder |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN101331917B (en) * | 2007-06-25 | 2012-07-04 | 上海海洋大学 | Eriocheir sinensis fattening feed nutrient additive |
| CN101411403B (en) * | 2008-11-05 | 2011-05-25 | 广东恒兴集团有限公司 | Feedstuff additive premix compound for Eriocheir sinensis |
| CN104430091B (en) * | 2014-12-01 | 2017-03-01 | 启东翔龙旅游开发有限公司 | A kind of ecological cultivation method of Eriocheir sinensiss |
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|---|---|---|---|---|
| CN102988678A (en) * | 2011-09-19 | 2013-03-27 | 天津瑞贝特科技发展有限公司 | Chinese medicinal composition with function of nourishing liver and tonifying kidney, and preparation method thereof |
| CN106614178A (en) * | 2016-11-17 | 2017-05-10 | 南京正源生物技术有限公司 | Composite preparation for preventing and treating water retention disease of river crab and application thereof |
| CN107469013A (en) * | 2017-09-21 | 2017-12-15 | 胡边文 | A kind of medicament and preparation method for being used to prevent and treat aquatic livestock disease in the liver and gallbladder |
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| Title |
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| 浅谈养殖河蟹应注意的问题与对策;张英;《中国水产》;19961031(第10期);第20-21页 * |
| 蟹类肝胰腺病症的病原和病理学研究进展;张瑶，等;《水产科技情报》;20120520;第40卷(第3期);第136-137页第2-3节 * |
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