CN108685753A - 改善类视色素的活性的方法 - Google Patents
改善类视色素的活性的方法 Download PDFInfo
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- CN108685753A CN108685753A CN201810265642.2A CN201810265642A CN108685753A CN 108685753 A CN108685753 A CN 108685753A CN 201810265642 A CN201810265642 A CN 201810265642A CN 108685753 A CN108685753 A CN 108685753A
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- retinoid
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- 239000011770 retinyl acetate Substances 0.000 description 1
- WWDMJSSVVPXVSV-YCNIQYBTSA-N retinyl ester Chemical compound CC1CCCC(C)(C)C1\C=C\C(\C)=C\C=C\C(\C)=C\C(O)=O WWDMJSSVVPXVSV-YCNIQYBTSA-N 0.000 description 1
- 229960002477 riboflavin Drugs 0.000 description 1
- 235000019192 riboflavin Nutrition 0.000 description 1
- 239000002151 riboflavin Substances 0.000 description 1
- 235000009566 rice Nutrition 0.000 description 1
- 238000007665 sagging Methods 0.000 description 1
- 229960004889 salicylic acid Drugs 0.000 description 1
- 150000003839 salts Chemical class 0.000 description 1
- 210000004761 scalp Anatomy 0.000 description 1
- 210000001732 sebaceous gland Anatomy 0.000 description 1
- DCKVNWZUADLDEH-UHFFFAOYSA-N sec-butyl acetate Chemical compound CCC(C)OC(C)=O DCKVNWZUADLDEH-UHFFFAOYSA-N 0.000 description 1
- 239000013049 sediment Substances 0.000 description 1
- 239000002453 shampoo Substances 0.000 description 1
- 239000008257 shaving cream Substances 0.000 description 1
- 229910052710 silicon Inorganic materials 0.000 description 1
- 239000010703 silicon Substances 0.000 description 1
- 239000000344 soap Substances 0.000 description 1
- FDRCDNZGSXJAFP-UHFFFAOYSA-M sodium chloroacetate Chemical compound [Na+].[O-]C(=O)CCl FDRCDNZGSXJAFP-UHFFFAOYSA-M 0.000 description 1
- HRZFUMHJMZEROT-UHFFFAOYSA-L sodium disulfite Chemical compound [Na+].[Na+].[O-]S(=O)S([O-])(=O)=O HRZFUMHJMZEROT-UHFFFAOYSA-L 0.000 description 1
- 235000010262 sodium metabisulphite Nutrition 0.000 description 1
- 235000019832 sodium triphosphate Nutrition 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 239000000600 sorbitol Substances 0.000 description 1
- 239000007921 spray Substances 0.000 description 1
- 229940031439 squalene Drugs 0.000 description 1
- TUHBEKDERLKLEC-UHFFFAOYSA-N squalene Natural products CC(=CCCC(=CCCC(=CCCC=C(/C)CCC=C(/C)CC=C(C)C)C)C)C TUHBEKDERLKLEC-UHFFFAOYSA-N 0.000 description 1
- 150000003432 sterols Chemical class 0.000 description 1
- 235000003702 sterols Nutrition 0.000 description 1
- 230000004936 stimulating effect Effects 0.000 description 1
- 239000000758 substrate Substances 0.000 description 1
- 239000005720 sucrose Substances 0.000 description 1
- 239000000516 sunscreening agent Substances 0.000 description 1
- 239000006228 supernatant Substances 0.000 description 1
- 239000000725 suspension Substances 0.000 description 1
- 210000004243 sweat Anatomy 0.000 description 1
- 229920001059 synthetic polymer Polymers 0.000 description 1
- 239000011975 tartaric acid Substances 0.000 description 1
- 235000002906 tartaric acid Nutrition 0.000 description 1
- 125000000383 tetramethylene group Chemical group [H]C([H])([*:1])C([H])([H])C([H])([H])C([H])([H])[*:2] 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 235000019157 thiamine Nutrition 0.000 description 1
- 150000003544 thiamines Chemical class 0.000 description 1
- 229960002663 thioctic acid Drugs 0.000 description 1
- 235000010384 tocopherol Nutrition 0.000 description 1
- 229960001295 tocopherol Drugs 0.000 description 1
- 235000019149 tocopherols Nutrition 0.000 description 1
- 229930003802 tocotrienol Natural products 0.000 description 1
- 239000011731 tocotrienol Substances 0.000 description 1
- 235000019148 tocotrienols Nutrition 0.000 description 1
- 229940068778 tocotrienols Drugs 0.000 description 1
- 231100000419 toxicity Toxicity 0.000 description 1
- 230000001988 toxicity Effects 0.000 description 1
- GTZCVFVGUGFEME-UHFFFAOYSA-N trans-aconitic acid Natural products OC(=O)CC(C(O)=O)=CC(O)=O GTZCVFVGUGFEME-UHFFFAOYSA-N 0.000 description 1
- 230000008733 trauma Effects 0.000 description 1
- 229940035936 ubiquinone Drugs 0.000 description 1
- 235000019160 vitamin B3 Nutrition 0.000 description 1
- 239000011708 vitamin B3 Substances 0.000 description 1
- 235000009492 vitamin B5 Nutrition 0.000 description 1
- 239000011675 vitamin B5 Substances 0.000 description 1
- 235000019154 vitamin C Nutrition 0.000 description 1
- 239000011718 vitamin C Substances 0.000 description 1
- 235000019168 vitamin K Nutrition 0.000 description 1
- 239000011712 vitamin K Substances 0.000 description 1
- 150000003721 vitamin K derivatives Chemical class 0.000 description 1
- 229940046010 vitamin k Drugs 0.000 description 1
- 229920001285 xanthan gum Polymers 0.000 description 1
- UHVMMEOXYDMDKI-JKYCWFKZSA-L zinc;1-(5-cyanopyridin-2-yl)-3-[(1s,2s)-2-(6-fluoro-2-hydroxy-3-propanoylphenyl)cyclopropyl]urea;diacetate Chemical compound [Zn+2].CC([O-])=O.CC([O-])=O.CCC(=O)C1=CC=C(F)C([C@H]2[C@H](C2)NC(=O)NC=2N=CC(=CC=2)C#N)=C1O UHVMMEOXYDMDKI-JKYCWFKZSA-L 0.000 description 1
- 235000004835 α-tocopherol Nutrition 0.000 description 1
- 239000002076 α-tocopherol Substances 0.000 description 1
- 235000007680 β-tocopherol Nutrition 0.000 description 1
- 239000011590 β-tocopherol Substances 0.000 description 1
- 239000002478 γ-tocopherol Substances 0.000 description 1
- QUEDXNHFTDJVIY-UHFFFAOYSA-N γ-tocopherol Chemical class OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1 QUEDXNHFTDJVIY-UHFFFAOYSA-N 0.000 description 1
- QUEDXNHFTDJVIY-DQCZWYHMSA-N γ-tocopherol Chemical compound OC1=C(C)C(C)=C2O[C@@](CCC[C@H](C)CCC[C@H](C)CCCC(C)C)(C)CCC2=C1 QUEDXNHFTDJVIY-DQCZWYHMSA-N 0.000 description 1
- 239000002446 δ-tocopherol Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
- A61K31/07—Retinol compounds, e.g. vitamin A
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/671—Vitamin A; Derivatives thereof, e.g. ester of vitamin A acid, ester of retinol, retinol, retinal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/716—Glucans
- A61K31/718—Starch or degraded starch, e.g. amylose, amylopectin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/732—Starch; Amylose; Amylopectin; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/81—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
- A61K8/8141—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides or nitriles thereof; Compositions of derivatives of such polymers
- A61K8/8152—Homopolymers or copolymers of esters, e.g. (meth)acrylic acid esters; Compositions of derivatives of such polymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/10—Anti-acne agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/10—Washing or bathing preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
- A61K2800/88—Two- or multipart kits
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Dermatology (AREA)
- Epidemiology (AREA)
- Birds (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Gerontology & Geriatric Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Cosmetics (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
Abstract
Description
处理 | IL-1α释放的平均值(pg/mL) |
未处理 | 77.9 |
清洁组合物A1 | 243.9 |
比较清洁组合物B2 | 888.3 |
比较清洁组合物C3 | 906.3 |
比较清洁组合物D4 | 91.3 |
Claims (21)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US15/475,516 | 2017-03-31 | ||
US15/475,516 US20180280275A1 (en) | 2017-03-31 | 2017-03-31 | Methods of Improving the Activity of Retinoids |
Publications (2)
Publication Number | Publication Date |
---|---|
CN108685753A true CN108685753A (zh) | 2018-10-23 |
CN108685753B CN108685753B (zh) | 2022-11-08 |
Family
ID=61868454
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
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CN201810265642.2A Active CN108685753B (zh) | 2017-03-31 | 2018-03-28 | 改善类视色素的活性的方法 |
Country Status (9)
Country | Link |
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US (2) | US20180280275A1 (zh) |
EP (2) | EP3381440A3 (zh) |
JP (2) | JP2018172373A (zh) |
KR (1) | KR20180111585A (zh) |
CN (1) | CN108685753B (zh) |
AU (1) | AU2018202184A1 (zh) |
BR (1) | BR102018006534B1 (zh) |
CA (1) | CA2999497A1 (zh) |
MX (1) | MX2018003954A (zh) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
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US11992639B2 (en) * | 2020-01-29 | 2024-05-28 | Katya Warner | Device for targeted dispensing of nourishing microcapsules to skin during sleep |
Citations (6)
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JP2001139453A (ja) * | 1999-11-19 | 2001-05-22 | Isehan:Kk | 皮膚外用剤 |
US20100311628A1 (en) * | 2006-11-09 | 2010-12-09 | Librizzi Joseph J | Low-irritation compositions and methods of making the same |
EP2314274A2 (en) * | 2009-10-07 | 2011-04-27 | Johnson & Johnson Consumer Companies, Inc. | Compositions comprising a superhydrophilic amphiphilic copolymer and a micellar thickener |
US20110251273A1 (en) * | 2008-12-22 | 2011-10-13 | Thierry Oddos | composition and method of treating skin conditions |
US20110319307A1 (en) * | 2010-06-24 | 2011-12-29 | Euen Thomas Graham Ekman Gunn | Low-irritating, clear cleansing compositions with relatively low ph |
CN102552062A (zh) * | 2010-12-21 | 2012-07-11 | 强生消费者公司 | 含有聚甘油酯和疏水改性聚合物的皮肤清洁组合物 |
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US2661349A (en) | 1949-02-18 | 1953-12-01 | Nat Starch Products Inc | Polysaccharide derivatives of substituted dicarboxylic acids |
US5954883A (en) | 1996-10-08 | 1999-09-21 | National Starch And Chemical Investment Holding Corporation | Waxy maize starch derived from grain of a plant which is heterozygous for the sugary-2 allele |
US5776476A (en) * | 1997-02-28 | 1998-07-07 | National Starch And Chemical Investment Holding Corporation | Cosmetic compositions containing hydrophobic starch derivatives |
US5997887A (en) * | 1997-11-10 | 1999-12-07 | The Procter & Gamble Company | Skin care compositions and method of improving skin appearance |
US6433061B1 (en) | 2000-10-24 | 2002-08-13 | Noveon Ip Holdings Corp. | Rheology modifying copolymer composition |
WO2002065995A1 (en) * | 2001-02-15 | 2002-08-29 | Yns Skin Center, Inc. | SKIN CARE COMPOSITION WITH RETINYL ESTER AS VITAMIN A PROPIONATE, RETINYL PALMITATE, d-ALPHA TOCOPHEROL, RICE AMINO ACIDS AND LIPOSOMES, AND METHOD OF APPLICATION |
DE10224298A1 (de) * | 2002-05-31 | 2003-12-18 | Beiersdorf Ag | Kosmetische Stoffkombinationen |
WO2010085753A1 (en) | 2009-01-23 | 2010-07-29 | Jr Chem, Llc | Rosacea treatments and kits for performing them |
US20110008271A1 (en) * | 2009-07-13 | 2011-01-13 | Jr Chem, Llc | Rosacea treatments using polymetal complexes |
US8258250B2 (en) | 2009-10-07 | 2012-09-04 | Johnson & Johnson Consumer Companies, Inc. | Compositions comprising superhydrophilic amphiphilic copolymers and methods of use thereof |
JP6284956B2 (ja) * | 2013-02-19 | 2018-02-28 | ジョンソン・アンド・ジョンソン・コンシューマー・インコーポレイテッド | 瘢痕組織の外観及び形成を改善するための方法並びに組成物 |
-
2017
- 2017-03-31 US US15/475,516 patent/US20180280275A1/en not_active Abandoned
-
2018
- 2018-03-27 KR KR1020180035100A patent/KR20180111585A/ko not_active Application Discontinuation
- 2018-03-27 CA CA2999497A patent/CA2999497A1/en active Pending
- 2018-03-27 AU AU2018202184A patent/AU2018202184A1/en not_active Abandoned
- 2018-03-28 MX MX2018003954A patent/MX2018003954A/es unknown
- 2018-03-28 CN CN201810265642.2A patent/CN108685753B/zh active Active
- 2018-03-29 BR BR102018006534-3A patent/BR102018006534B1/pt active IP Right Grant
- 2018-03-30 JP JP2018067295A patent/JP2018172373A/ja active Pending
- 2018-04-03 EP EP18165449.2A patent/EP3381440A3/en not_active Withdrawn
- 2018-04-03 EP EP20203850.1A patent/EP3789009A1/en not_active Withdrawn
- 2018-11-28 US US16/202,198 patent/US20190091125A1/en not_active Abandoned
-
2023
- 2023-04-10 JP JP2023063300A patent/JP2023076747A/ja active Pending
Patent Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
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JP2001139453A (ja) * | 1999-11-19 | 2001-05-22 | Isehan:Kk | 皮膚外用剤 |
US20100311628A1 (en) * | 2006-11-09 | 2010-12-09 | Librizzi Joseph J | Low-irritation compositions and methods of making the same |
US20110251273A1 (en) * | 2008-12-22 | 2011-10-13 | Thierry Oddos | composition and method of treating skin conditions |
EP2314274A2 (en) * | 2009-10-07 | 2011-04-27 | Johnson & Johnson Consumer Companies, Inc. | Compositions comprising a superhydrophilic amphiphilic copolymer and a micellar thickener |
US20110319307A1 (en) * | 2010-06-24 | 2011-12-29 | Euen Thomas Graham Ekman Gunn | Low-irritating, clear cleansing compositions with relatively low ph |
CN102552062A (zh) * | 2010-12-21 | 2012-07-11 | 强生消费者公司 | 含有聚甘油酯和疏水改性聚合物的皮肤清洁组合物 |
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Also Published As
Publication number | Publication date |
---|---|
CA2999497A1 (en) | 2018-09-30 |
US20180280275A1 (en) | 2018-10-04 |
CN108685753B (zh) | 2022-11-08 |
KR20180111585A (ko) | 2018-10-11 |
JP2018172373A (ja) | 2018-11-08 |
BR102018006534A8 (pt) | 2022-08-09 |
AU2018202184A1 (en) | 2018-10-18 |
JP2023076747A (ja) | 2023-06-01 |
BR102018006534A2 (pt) | 2018-10-30 |
RU2018110601A3 (zh) | 2021-10-26 |
EP3789009A1 (en) | 2021-03-10 |
RU2018110601A (ru) | 2019-09-26 |
BR102018006534B1 (pt) | 2023-04-25 |
US20190091125A1 (en) | 2019-03-28 |
EP3381440A3 (en) | 2019-01-16 |
MX2018003954A (es) | 2018-11-22 |
EP3381440A2 (en) | 2018-10-03 |
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