CN108653504A

CN108653504A - A kind of drug and preparation method thereof for treating ankylosing spondylitis

Info

Publication number: CN108653504A
Application number: CN201810676157.4A
Authority: CN
Inventors: 赖祥林; 李开静; 赖昌生; 刘宇河
Original assignee: Department Of Orthopedics Yulin Traditional Chinese And Western Medicine
Current assignee: Department Of Orthopedics Yulin Traditional Chinese And Western Medicine
Priority date: 2018-06-27
Filing date: 2018-06-27
Publication date: 2018-10-16

Abstract

The invention discloses a kind of drugs for treating ankylosing spondylitis, belong to the field of Chinese medicines.The drug, including following parts by weight of component：8~15 parts of stiff silkworm, 8~18 parts of scythian lamb rhizome, 10~22 parts of Chinese herbaceous peony, 8~15 parts of Fructus Chaenomelis, 8~15 parts of the root of Chinese clematis, 15~35 parts of xanthorrhiza, 15~28 parts of tripterygium wilfordii, 18~34 parts of Caulis Spatholobi, 8~18 parts of snapper eye, 8~14 parts of caulis sinomenii, 8~18 parts of black tiger, 5~15 parts of Radix Angelicae Pubescentis, 5~15 parts of bark of ash, 8~18 parts of Pterospermi Heterophylli, 8~18 parts of Sassafras tsumu Hemsl, 8~15 parts of paniculate swallowwort, 10~18 parts of caulis trachelospermi, 10~20 parts of Cortex Eucommiae, 10~20 parts of Radix Astragali, 5~10 parts of Radix Angelicae Sinensis, 7~17 parts of waras, 1~10 part of 8~18 parts of rhizoma homalonemae and Radix Glycyrrhizae.The present invention also provides the preparation methods of said medicine.

Description

A kind of drug and preparation method thereof for treating ankylosing spondylitis

Technical field

The invention belongs to Chinese medicine and its to preparation field, especially a kind of drug for treating ankylosing spondylitis and its preparation Method.

Background technology

Ankylosing spondylitis referred to as tetanic, english abbreviation AS, is caused by a kind of chronic generalized immune system disorder Disease with backbone and sacrum bone system and is ossify mainly to show.Chinese medicine category heumatism, kidney-energy stagnation syndrome, the stupid numbness of severe and wadering arthralgia, ring demeanour farmland, Take male as common, waist, neck, the inflammation of chest section joint of vertebral column and ossified.Hip joint is usually involved, other periarticulars may also There is inflammation.It is intermittence to start pain, and duration-is developed into after several years several months and inflammatory pain disappears, backbone is under And it is upper or all tetanic, there is bow-backed deformity.This disease is relatively conventional disease, and the course of disease is touching with the passing of time, be easy to cause deformity.Such as Fruit early stage can treat in time, can reach the purpose of rehabilitation.

Western medical treatment mostly uses based on non-steroid anti-inflammatory drug and salicylazosulfapyridine and methotrexate, biological agent, But curative effect is undesirable.But the side effect using chemotherapy and cancer drug therapy is larger, and dependence is very strong, costly.

Therefore seek it is a kind of to this disease with good result and without side-effects, the lower pure Chinese medicine natural medicine of dependence As one of the focus on research direction in industry.

Invention content

There is good result one of the objects of the present invention is to provide one kind and without side-effects, the lower treatment of dependence is by force The drug of straightforward rachitis.

The second object of the present invention is to provide the preparation method of said medicine.

In order to realize above-mentioned first technical purpose, scheme provided by the invention is such：It is a kind of to treat tatanic ridge The drug of column inflammation, including following parts by weight of component：8~15 parts of stiff silkworm, 8~18 parts of scythian lamb rhizome, 10~22 parts of Chinese herbaceous peony, Fructus Chaenomelis 8~15 parts, 8~15 parts of the root of Chinese clematis, 15~35 parts of xanthorrhiza, 15~28 parts of tripterygium wilfordii, 18~34 parts of Caulis Spatholobi, snapper eye 8~18 Part, 8~14 parts of caulis sinomenii, 8~18 parts of black tiger, 5~15 parts of Radix Angelicae Pubescentis, 5~15 parts of bark of ash, 8~18 parts of Pterospermi Heterophylli, Sassafras tsumu Hemsl 8 ~18 parts, 8~15 parts of paniculate swallowwort, 10~18 parts of caulis trachelospermi, 10~20 parts of Cortex Eucommiae, 10~20 parts of Radix Astragali, 5~10 parts of Radix Angelicae Sinensis, thousand Jin pulls out 7~17 parts, 1~10 part of 8~18 parts of rhizoma homalonemae and Radix Glycyrrhizae.

Preferably, including following parts by weight of component：12 parts of stiff silkworm, 15 parts of scythian lamb rhizome, 12 parts of Chinese herbaceous peony, 12 parts of Fructus Chaenomelis, 12 parts of the root of Chinese clematis, 30 parts of xanthorrhiza, 25 parts of tripterygium wilfordii, 30 parts of Caulis Spatholobi, snapper eye 15 parts, 12 parts of caulis sinomenii, 15 parts of black tiger, solely 10 parts living, 10 parts of bark of ash, 15 parts of Pterospermi Heterophylli, 15 parts of Sassafras tsumu Hemsl, 12 parts of paniculate swallowwort, 15 parts of caulis trachelospermi, 15 parts of Cortex Eucommiae, Radix Astragali 15 Part, 6 parts of Radix Angelicae Sinensis, 15 parts of waras, 15 parts of rhizoma homalonemae and 6 parts of Radix Glycyrrhizae.

Preferably, including following parts by weight of component：10 parts of stiff silkworm, 10 parts of scythian lamb rhizome, 20 parts of Chinese herbaceous peony, 10 parts of Fructus Chaenomelis, 10 parts of the root of Chinese clematis, 20 parts of xanthorrhiza, 20 parts of tripterygium wilfordii, 20 parts of Caulis Spatholobi, snapper eye 10 parts, 10 parts of caulis sinomenii, 10 parts of black tiger, solely 7 parts living, 7 parts of bark of ash, 10 parts of Pterospermi Heterophylli, 10 parts of Sassafras tsumu Hemsl, 10 parts of paniculate swallowwort, 12 parts of caulis trachelospermi, 15 parts of Cortex Eucommiae, 15 parts of Radix Astragali, 3 parts of 6 parts of Radix Angelicae Sinensis, 10 parts of waras, 10 parts of rhizoma homalonemae and Radix Glycyrrhizae.

Preferably, further include following parts by weight of component：It is 5~15 parts of avicenna pricklyash root, 1~5 part of Rhizoma Chuanxiong, 5~15 parts of radix achyranthis bidentatae, white 5~15 parts of Poria cocos, 5~15 parts of teasel and 5~15 parts of bone of war.

Preferably, further include following parts by weight of component：10 parts of avicenna pricklyash root, 3 parts of Rhizoma Chuanxiong, 10 parts of radix achyranthis bidentatae, 10 parts of PORIA ALBA, 10 parts of teasel and 10 parts of bone of war.

Preferably, the drug is decoction, powder, tablet, electuary or capsule.

In order to realize above-mentioned second technical purpose, technical solution provided by the invention is such：It is a kind of as described above Treat ankylosing spondylitis drug preparation method, by scythian lamb rhizome, tripterygium wilfordii, xanthorrhiza, Caulis Spatholobi, snapper eye, caulis sinomenii, Black tiger, Radix Angelicae Pubescentis, bark of ash, Pterospermi Heterophylli, tree ginseng, caulis trachelospermi, rhizoma homalonemae and Cortex Eucommiae are mixed with 1500~2500 parts of water, are boiled by intense fire 25~35min, then slow boiling are endured to medicinal extract；By other Chinese medicines crush be added, be uniformly mixed, drying, crush to get.

A kind of preparation method of the drug for the treatment of ankylosing spondylitis as described above, by scythian lamb rhizome, avicenna pricklyash root, Thunder God Rattan, xanthorrhiza, Caulis Spatholobi, snapper eye, caulis sinomenii, black tiger, Radix Angelicae Pubescentis, Rhizoma Chuanxiong, bark of ash, Pterospermi Heterophylli, Sassafras tsumu Hemsl, caulis trachelospermi, thousand Strong, teasel and Cortex Eucommiae are mixed with 1500~2500 parts of water, boil 25~35min by intense fire, then slow boiling is endured to medicinal extract；It will be in other The broken addition of medicinal powder, be uniformly mixed, drying, crush to get.

Preferably, described that remaining traditional Chinese medicinal components are smashed it through into 180-220 mesh sieve, it is added.

Preferably, described that remaining traditional Chinese medicinal components are smashed it through into 200 mesh sieve, it is added.

The present invention has the following advantages compared with conventional method：

In the present invention：The larva of a silkworm with batrytis has the effect of wind-expelling pain-stopping, relieving convulsion and spasm, reducing phlegm and resolving masses, and taste is salty pungent flat, enters liver lung two Through；Scythian lamb rhizome has the effect of dispelling wind and eliminating dampness, filling liver kidney strong spinal column；There is RADIX PAEONIAE ALBA nourishing blood and liver, relieving spasm to stop pain, spasmolysis to relax The effect of muscle；Fructus Chaenomelis has the benefits of relaxing tendons and activating collaterals, expelling pathogenic wind and promoting blood circulation, strong tendon and vessel, dampness elimination analgesic；Root of Chinese clematis acrid flavour saltiness temperature, tool There are dispelling wind and eliminating dampness, the active effect of dysmenorrhoea to be suitable for arthralgia pain due to rheumatism, muscle arteries and veins contraction, joint stuffiness, extremity numbness, lumbar vertebrae pain Patient；Avicenna pricklyash root has the effect of wind dispelling dampness elimination, remove obstruction in channels to relieve pain；Xanthorrhiza dissipates stasis of blood strengthening tendons, hemostasis dampness removing, can be used for treating bone and closes Save disease；Tripterygium wilfordii has the effect of promoting blood circulation and removing obstruction in channels, swelling and pain relieving, and it is stupid to be usually used in treatment rheumatism, rheumatoid, erythematosus lupus etc. Solidity disease, but it is toxic, it can be taken after preferably decocting long；Caulis Spatholobi is activated blood and relaxed tendons, and numb in every limb, quadriplegia, spinal column numbness are cured mainly Pain etc.；Snapper eye promoting blood circulation by removing wind, eliminating stasis to subdue swelling, have better effects to ankylosing spondylitis；Caulis sinomenii have remove obstruction in channels to relieve pain, wind-dispelling The effect of dehumidifying；Black tiger has the effect of numbness is controlled in removing blood stasis and analgesics, dispelling wind and eliminating dampness, detumescence；Radix Angelicae Pubescentis, bark of ash, Rhizoma Chuanxiong are removed with wind-dispelling Stagnant effect is led in wet, eliminating cold to stop pain, relaxing tendons and activating collaterals, stagnation resolvation；It is Pterospermi Heterophylli dispelling wind and eliminating dampness, promoting blood circulation and removing obstruction in channels；Sassafras tsumu Hemsl dispelling wind and eliminating dampness, work Blood dissipates the stasis of blood, cures mainly the diseases such as Bi condition, traumatic injury, lumbar muscular injury, spinal column numbness pain；Paniculate swallowwort promoting blood circulation by removing wind, detumescence of alleviating pain；Network Stone rattan dispelling wind and removing obstruction in the meridians, cool blood detumescence take out contraction, Yao Xi Acid pains, the key medicine of ridge item pain for treatment beriberoid pyretic arthralgia, tendon and vessel；Cortex Eucommiae, Teasel has effects that tonify the liver and kidney, strengthens muscles and bones, raises blood vessels；Radix achyranthis bidentatae strengthening the bones and muscles, filling liver kidney, is apt to control waist at scattered blood stasis The diseases such as kneecap pain, spasm of limbs, spinal column Impotence numbness；Radix Astragali, Radix Angelicae Sinensis nourishing qi and blood, invigorating qi and dredging collateral；Waras, rhizoma homalonemae tool wind-dispelling remove Wet, relaxing tendons and activating collaterals, strengthen muscles and bones, liver-nourishing kidney-boosting, strong waist strong ridge the effect of；PORIA ALBA invigorating spleen to remove dampness, Radix Glycyrrhizae coordinating the drug actions of a prescription.

Above-mentioned all medicine is subjected to scientific compatibility, with the larva of a silkworm with batrytis, snapper eye, tripterygium wilfordii, scythian lamb rhizome, Thunder God wood, the root of Chinese clematis, Fructus Chaenomelis wind expelling stagnation removing, strengthening tendons strengthen ridge, and it is monarch drug in a prescription that dredging collateral, which takes advantage of pain,；With dog bone wood, RADIX PAEONIAE ALBA, rhizoma homalonemae, waras, Caulis Spatholobi, The wind dispellings such as black tiger, solely words, war bone, bark of ash, Pterospermi Heterophylli, Sassafras tsumu Hemsl are wet, exempt from numbness pain, and restoring and treating injured soft tissues network is ministerial drug；With paniculate swallowwort, river Rhizome of chuanxiong, radix achyranthis bidentatae, caulis trachelospermi, Radix Angelicae Sinensis are as adjutant；With filling liver kidney such as astragali, Cortex Eucommiae, teasel, PORIA ALBA, Radix Glycyrrhizaes, QI invigorating and In to make medicine.All medicines share, gathers wind dispelling Strong ridges altogether, and stagnation resolvation removes Paralysis, adjusts nourishing liver and kidney, benefiting qi and nourishing blood, the benefits of unfolding muscles and bones, for controlling The effect for the treatment of ankylosing spondylitis is notable, and side effect is smaller, and dependence is low, and expense is relatively low；And preparation method is simple, can both make in a small amount It is standby, it is also applied for industrial big production.

Specific implementation mode

With reference to embodiment, the claim of the present invention is described in further detail, but do not constituted pair Any restrictions of the present invention, any limited number of time modification made in the claims in the present invention protection domain, still the present invention's In claims.

Embodiment 1

8 parts of stiff silkworm, 18 parts of scythian lamb rhizome, 10 parts of Chinese herbaceous peony, 15 parts of Fructus Chaenomelis, 8 parts of the root of Chinese clematis, 35 parts of xanthorrhiza, tripterygium wilfordii 15 Part, 34 parts of Caulis Spatholobi, 8 parts of snapper eye, 14 parts of caulis sinomenii, 8 parts of black tiger, 15 parts of Radix Angelicae Pubescentis, 5 parts of bark of ash, 18 parts of Pterospermi Heterophylli, maple lotus 8 parts of osmanthus, 5 parts of paniculate swallowwort, 10 parts of caulis trachelospermi, 20 parts of Cortex Eucommiae, 10 parts of Radix Astragali, 10 parts of Radix Angelicae Sinensis, 7 parts of waras, 18 parts of rhizoma homalonemae and 1 part of Radix Glycyrrhizae.

Embodiment 2

15 parts of stiff silkworm, 8 parts of scythian lamb rhizome, 22 parts of Chinese herbaceous peony, 8 parts of Fructus Chaenomelis, 15 parts of the root of Chinese clematis, 15 parts of xanthorrhiza, tripterygium wilfordii 28 Part, 18 parts of Caulis Spatholobi, 18 parts of snapper eye, 8 parts of caulis sinomenii, 18 parts of black tiger, 5 parts of Radix Angelicae Pubescentis, 15 parts of bark of ash, 8 parts of Pterospermi Heterophylli, maple lotus 18 parts of osmanthus, 8 parts of paniculate swallowwort, 18 parts of caulis trachelospermi, 10 parts of Cortex Eucommiae, 20 parts of Radix Astragali, 5 parts of Radix Angelicae Sinensis, 17 parts of waras, 8 parts of rhizoma homalonemae and 10 parts of Radix Glycyrrhizae.

Embodiment 3

12 parts of stiff silkworm, 15 parts of scythian lamb rhizome, 12 parts of Chinese herbaceous peony, 12 parts of Fructus Chaenomelis, 12 parts of the root of Chinese clematis, 30 parts of xanthorrhiza, tripterygium wilfordii 25 parts, 30 parts of Caulis Spatholobi, snapper eye 15 parts, 12 parts of caulis sinomenii, 15 parts of black tiger, 10 parts of Radix Angelicae Pubescentis, 10 parts of bark of ash, Pterospermi Heterophylli 15 Part, 15 parts of Sassafras tsumu Hemsl, 12 parts of paniculate swallowwort, 15 parts of caulis trachelospermi, 15 parts of Cortex Eucommiae, 15 parts of Radix Astragali, 6 parts of Radix Angelicae Sinensis, 15 parts, thousand of waras Strong 15 parts and 6 parts of Radix Glycyrrhizae.

Embodiment 4

10 parts of stiff silkworm, 10 parts of scythian lamb rhizome, 20 parts of Chinese herbaceous peony, 10 parts of Fructus Chaenomelis, 10 parts of the root of Chinese clematis, 20 parts of xanthorrhiza, tripterygium wilfordii 20 parts, 20 parts of Caulis Spatholobi, snapper eye 10 parts, 10 parts of caulis sinomenii, 10 parts of black tiger, 7 parts of Radix Angelicae Pubescentis, 7 parts of bark of ash, 10 parts of Pterospermi Heterophylli, 10 parts of Sassafras tsumu Hemsl, 10 parts of paniculate swallowwort, 12 parts of caulis trachelospermi, 15 parts of Cortex Eucommiae, 15 parts of Radix Astragali, 6 parts of Radix Angelicae Sinensis, 10 parts of waras, rhizoma homalonemae 10 parts and 3 parts of Radix Glycyrrhizae.

The preparation method of embodiment 1-4 is：By scythian lamb rhizome, tripterygium wilfordii, xanthorrhiza, Caulis Spatholobi, snapper eye, caulis sinomenii, black Tiger, Radix Angelicae Pubescentis, bark of ash, Pterospermi Heterophylli, tree ginseng, caulis trachelospermi, rhizoma homalonemae and Cortex Eucommiae are mixed with 1500~2500 parts of water, boil 25 by intense fire ~35min, then slow boiling are endured to medicinal extract；By other Chinese medicines be crushed to 200 mesh be added, be uniformly mixed, drying, crush to get.

Embodiment 5

8 parts of stiff silkworm, 18 parts of scythian lamb rhizome, 10 parts of Chinese herbaceous peony, 15 parts of Fructus Chaenomelis, 8 parts of the root of Chinese clematis, 35 parts of xanthorrhiza, tripterygium wilfordii 15 Part, 34 parts of Caulis Spatholobi, 8 parts of snapper eye, 14 parts of caulis sinomenii, 8 parts of black tiger, 15 parts of Radix Angelicae Pubescentis, 5 parts of bark of ash, 18 parts of Pterospermi Heterophylli, maple lotus It is 8 parts of osmanthus, 5 parts of paniculate swallowwort, 10 parts of caulis trachelospermi, 20 parts of Cortex Eucommiae, 10 parts of Radix Astragali, 10 parts of Radix Angelicae Sinensis, 7 parts of waras, 18 parts of rhizoma homalonemae, sweet 1 part of grass, 15 parts of avicenna pricklyash root, 1 part of Rhizoma Chuanxiong, 15 parts of radix achyranthis bidentatae, 5 parts of PORIA ALBA, 15 parts of teasel and 5 parts of bone of war.

Embodiment 6

15 parts of stiff silkworm, 8 parts of scythian lamb rhizome, 22 parts of Chinese herbaceous peony, 8 parts of Fructus Chaenomelis, 15 parts of the root of Chinese clematis, 15 parts of xanthorrhiza, tripterygium wilfordii 28 Part, 18 parts of Caulis Spatholobi, 18 parts of snapper eye, 8 parts of caulis sinomenii, 18 parts of black tiger, 5 parts of Radix Angelicae Pubescentis, 15 parts of bark of ash, 8 parts of Pterospermi Heterophylli, maple lotus It is 18 parts of osmanthus, 8 parts of paniculate swallowwort, 18 parts of caulis trachelospermi, 10 parts of Cortex Eucommiae, 20 parts of Radix Astragali, 5 parts of Radix Angelicae Sinensis, 17 parts of waras, 8 parts of rhizoma homalonemae, sweet 10 parts of grass, 5 parts of avicenna pricklyash root, 5 parts of Rhizoma Chuanxiong, 5 parts of radix achyranthis bidentatae, 15 parts of PORIA ALBA, 5 parts of teasel and 15 parts of bone of war.

Embodiment 7

12 parts of stiff silkworm, 15 parts of scythian lamb rhizome, 12 parts of Chinese herbaceous peony, 12 parts of Fructus Chaenomelis, 12 parts of the root of Chinese clematis, 30 parts of xanthorrhiza, tripterygium wilfordii 25 parts, 30 parts of Caulis Spatholobi, snapper eye 15 parts, 12 parts of caulis sinomenii, 15 parts of black tiger, 10 parts of Radix Angelicae Pubescentis, 10 parts of bark of ash, Pterospermi Heterophylli 15 Part, 15 parts of Sassafras tsumu Hemsl, 12 parts of paniculate swallowwort, 15 parts of caulis trachelospermi, 15 parts of Cortex Eucommiae, 15 parts of Radix Astragali, 6 parts of Radix Angelicae Sinensis, 15 parts, thousand of waras 15 parts strong, 6 parts of Radix Glycyrrhizae, 10 parts of avicenna pricklyash root, 3 parts of Rhizoma Chuanxiong, 10 parts of radix achyranthis bidentatae, 10 parts of PORIA ALBA, 10 parts of teasel and 10 parts of bone of war.

Embodiment 8

10 parts of stiff silkworm, 10 parts of scythian lamb rhizome, 20 parts of Chinese herbaceous peony, 10 parts of Fructus Chaenomelis, 10 parts of the root of Chinese clematis, 20 parts of xanthorrhiza, tripterygium wilfordii 20 parts, 20 parts of Caulis Spatholobi, snapper eye 10 parts, 10 parts of caulis sinomenii, 10 parts of black tiger, 7 parts of Radix Angelicae Pubescentis, 7 parts of bark of ash, 10 parts of Pterospermi Heterophylli, 10 parts of Sassafras tsumu Hemsl, 10 parts of paniculate swallowwort, 12 parts of caulis trachelospermi, 15 parts of Cortex Eucommiae, 15 parts of Radix Astragali, 6 parts of Radix Angelicae Sinensis, 10 parts of waras, rhizoma homalonemae 10 parts, 3 parts of Radix Glycyrrhizae, 10 parts of avicenna pricklyash root, 3 parts of Rhizoma Chuanxiong, 10 parts of radix achyranthis bidentatae, 10 parts of PORIA ALBA, 10 parts of teasel and 10 parts of bone of war.

The preparation method of embodiment 5-8 is：By scythian lamb rhizome, avicenna pricklyash root, tripterygium wilfordii, xanthorrhiza, Caulis Spatholobi, snapper eye, blueness Wind rattan, black tiger, Radix Angelicae Pubescentis, Rhizoma Chuanxiong, bark of ash, Pterospermi Heterophylli, Sassafras tsumu Hemsl, caulis trachelospermi, rhizoma homalonemae, teasel and Cortex Eucommiae with 1500~ 2500 parts of water mixing, boil 25~35min by intense fire, then slow boiling is endured to medicinal extract；Other Chinese medicines are crushed to 200 mesh to be added, mixing Uniformly, dry, crush to get.

Curative effect judges：

1. case selection：Treatment group 100, it is 16~52 years old age, 27.3 years old average.

2. therapeutic scheme：100 patient's drugs using the present invention are treated, daily 1 pair, decocting 2 times, are divided 3 times, Aftermeals.

3. the standard of curative effect evaluation：Clinical remission：Low-back pain disappears, without the performances such as stiff, limitation of activity, erythrocyte sedimentation rate, C- Reactive protein is normal.It is effective：Low-back pain disappears substantially, occasionally has stiff, limitation of activity sense, erythrocyte sedimentation rate, C reactive protein normal Or close to normally.Effectively：The clinical symptoms such as low-back pain and sign have and improve to a certain degree, and erythrocyte sedimentation rate, C reactive protein, which have, to be changed It is kind.In vain：The clinical symptoms such as low-back pain and sign are without improvement, and erythrocyte sedimentation rate, C reactive protein are without improvement.

4. result：Clinical remission 21, effective 49, effective 25, invalid 5, total effective rate 95%.

3 model cases are lifted below：

(1) poplar, female, 22 years old.Patient is because of waist stern hip pain repeatedly, and back is firmly tetanic, limitation of activity 4 years, aggravates 3 weeks To examine.Quarter examines：Complexion is slightly pale, and body is become thin, unfavorable, the difficulty of bending over of neck rotation, knee joint slightly enlargement, pink tongue, and tongue is white It is greasy, slippery.It is diagnosed as ankylosing spondylitis according to medical history, sign and imageological examination, using drug therapy of the present invention, after 8 days Waist stern hip pain slightly improves, and back is firmly tetanic slightly to be alleviated, and neck, waist activity are slightly good, lose heart, weak mitigation.Continual cure 6 Week, symptom and sign further improve, and erythrocyte sedimentation rate, C reactive protein are normal, and follow-up half a year is without recurrence.

(2) Lee, man, 29 years old.Patient aggravated January to examine because of the heavy pain recurrent exerbation of lumbosacral region more than 4 years.Quarter examines：Waist Portion, double hip joint pain, limitation of activity, exacerbation of suffering from cold, inconvenient walking, hands and feet being not warm is sleepy weak, pink tongue, and tongue is thin slightly yellow, Deeptensepulse.It is diagnosed as ankylosing spondylitis according to medical history, sign and imageological examination, using drug therapy of the present invention, morning after 6 days Deadlock, waist, hip pain mitigate, and brothers turn temperature.Continual cure 12 weeks, symptom and sign further improves, erythrocyte sedimentation rate, C reactive protein Close to normally, follow-up half a year is without recurrence.

(3) Mr. Wang, male, 43 years old.Patient examines because of lumbago repeatedly over more than 10 years.Quarter examines：Backbone all directions limited range of motion, The light tenderness of double hip joint, bilateral hip joint all directions limitation of activity, dark tongue quality, tongue is thin white, slippery.According to medical history, sign and shadow It is diagnosed as ankylosing spondylitis as learning inspection, using drug therapy of the present invention, low-back pain mitigates after 2 weeks, and backbone and hip close Section activity is slightly good.Continual cure 5 weeks, low-back pain disappear, and backbone and hip joint activity are slightly limited, erythrocyte sedimentation rate, C reactive protein There is improvement.

Claims

1. a kind of drug for treating ankylosing spondylitis, which is characterized in that including following parts by weight of component：8~15 parts of stiff silkworm, gold 8~18 parts of rhizoma cibotii of hair, 10~22 parts of Chinese herbaceous peony, 8~15 parts of Fructus Chaenomelis, 8~15 parts of the root of Chinese clematis, 15~35 parts of xanthorrhiza, tripterygium wilfordii 15 ~28 parts, 18~34 parts of Caulis Spatholobi, snapper eye 8~18 parts, 8~14 parts of caulis sinomenii, 8~18 parts of black tiger, 5~15 parts of Radix Angelicae Pubescentis, 5~15 parts of bark of ash, 8~18 parts of Pterospermi Heterophylli, 8~18 parts of Sassafras tsumu Hemsl, 8~15 parts of paniculate swallowwort, 10~18 parts of caulis trachelospermi, Cortex Eucommiae 10~ 1~10 part of 20 parts, 10~20 parts of Radix Astragali, 5~10 parts of Radix Angelicae Sinensis, 7~17 parts of waras, 8~18 parts of rhizoma homalonemae and Radix Glycyrrhizae.

2. treating the drug of ankylosing spondylitis according to claim 1, which is characterized in that including following parts by weight of component： 12 parts of stiff silkworm, 15 parts of scythian lamb rhizome, 12 parts of Chinese herbaceous peony, 12 parts of Fructus Chaenomelis, 12 parts of the root of Chinese clematis, 30 parts of xanthorrhiza, 25 parts of tripterygium wilfordii, chicken blood 30 parts of rattan, 15 parts of snapper eye, 12 parts of caulis sinomenii, 15 parts of black tiger, 10 parts of Radix Angelicae Pubescentis, 10 parts of bark of ash, 15 parts of Pterospermi Heterophylli, Sassafras tsumu Hemsl 15 Part, 12 parts of paniculate swallowwort, 15 parts of caulis trachelospermi, 15 parts of Cortex Eucommiae, 15 parts of Radix Astragali, 6 parts of Radix Angelicae Sinensis, 15 parts of waras, 15 parts of rhizoma homalonemae and sweet 6 parts of grass.

3. treating the drug of ankylosing spondylitis according to claim 1, which is characterized in that including following parts by weight of component： 10 parts of stiff silkworm, 10 parts of scythian lamb rhizome, 20 parts of Chinese herbaceous peony, 10 parts of Fructus Chaenomelis, 10 parts of the root of Chinese clematis, 20 parts of xanthorrhiza, 20 parts of tripterygium wilfordii, chicken blood 20 parts of rattan, 10 parts of snapper eye, 10 parts of caulis sinomenii, 10 parts of black tiger, 7 parts of Radix Angelicae Pubescentis, 7 parts of bark of ash, 10 parts of Pterospermi Heterophylli, Sassafras tsumu Hemsl 10 Part, 10 parts of paniculate swallowwort, 12 parts of caulis trachelospermi, 15 parts of Cortex Eucommiae, 15 parts of Radix Astragali, 6 parts of Radix Angelicae Sinensis, 10 parts of waras, 10 parts of rhizoma homalonemae and sweet 3 parts of grass.

4. according to the drug of any treatment ankylosing spondylitis of claim 1-3, which is characterized in that further include following weight Part component：5~15 parts of avicenna pricklyash root, 1~5 part of Rhizoma Chuanxiong, 5~15 parts of radix achyranthis bidentatae, 5~15 parts of PORIA ALBA, 5~15 parts of teasel and war 5~15 parts of bone.

5. according to the drug of any treatment ankylosing spondylitis of claim 1-3, which is characterized in that further include following weight Part component：10 parts of avicenna pricklyash root, 3 parts of Rhizoma Chuanxiong, 10 parts of radix achyranthis bidentatae, 10 parts of PORIA ALBA, 10 parts of teasel and 10 parts of bone of war.

6. treating the drug of ankylosing spondylitis according to claim 1, which is characterized in that the drug is decoction, dissipates Agent, tablet, electuary or capsule.

7. a kind of preparation method of the drug for the treatment of ankylosing spondylitis as described in claim 1, which is characterized in that by Cibotium barometz Ridge, tripterygium wilfordii, xanthorrhiza, Caulis Spatholobi, snapper eye, caulis sinomenii, black tiger, Radix Angelicae Pubescentis, bark of ash, Pterospermi Heterophylli, tree ginseng, caulis trachelospermi, thousand Strong and Cortex Eucommiae is mixed with 1500~2500 parts of water, boils 25~35min by intense fire, then slow boiling is endured to medicinal extract；By remaining traditional Chinese medicinal components Crush be added, be uniformly mixed, drying, crush to get.

8. a kind of preparation method of the drug for the treatment of ankylosing spondylitis as claimed in claim 4, which is characterized in that by Cibotium barometz Ridge, avicenna pricklyash root, tripterygium wilfordii, xanthorrhiza, Caulis Spatholobi, snapper eye, caulis sinomenii, black tiger, Radix Angelicae Pubescentis, Rhizoma Chuanxiong, bark of ash, Pterospermi Heterophylli, maple lotus Osmanthus, caulis trachelospermi, rhizoma homalonemae, teasel and Cortex Eucommiae are mixed with 1500~2500 parts of water, boil 25~35min by intense fire, then slow boiling is endured To medicinal extract；By remaining traditional Chinese medicinal components crush after, be added, be uniformly mixed, drying, crush to get.

9. according to the preparation method of the drug of the treatment ankylosing spondylitis of claim 7 or 8, which is characterized in that described to incite somebody to action Remaining traditional Chinese medicinal components smash it through 180-220 mesh sieve, are added.

10. according to the preparation method of the drug of the treatment ankylosing spondylitis of claim 7 or 8, which is characterized in that described to incite somebody to action Remaining traditional Chinese medicinal components smash it through 200 mesh sieve, are added.