CN108635395A

CN108635395A - Radix Codonopsis is fresh to carry freeze-drying granule pieces

Info

Publication number: CN108635395A
Application number: CN201810733205.9A
Authority: CN
Inventors: 徐事成
Original assignee: Wuhu Tiancheng Puyang Traditional Chinese Medicine Technology Co Ltd
Current assignee: Wuhu Tiancheng Puyang Traditional Chinese Medicine Technology Co Ltd
Priority date: 2018-07-06
Filing date: 2018-07-06
Publication date: 2018-10-12

Abstract

The invention discloses a kind of " Radix Codonopsis is fresh to carry freeze-drying granule pieces ", are primarily characterized in that：Radix Codonopsis harvesting after, take advantage of it is fresh wash, be sliced, squeezing the juice, extracting, extracting solution is freeze-dried after being condensed into clear cream, then is vacuum-packed after crushing, granulation, drying, whole grain.The water content of granule pieces is not higher than 10%.This prepared slice quality is stablized, and can both enter decoction decocting, can also directly enter pill, powder, tablet, capsule, is conducive to carry, Clinical practice is convenient.

Description

Radix Codonopsis is fresh to carry freeze-drying granule pieces

Technical field

The invention belongs to prepared slices of Chinese crude drugs technical fields, especially belong to the manufacture field of Radix Codonopsis medicine materical crude slice.

Background technology

Chinese medicine Radix Codonopsis is Campanulaceae Radix Codonopsis, codonopsis pilosula var. modesta or the dry root of radix codonpsis tangshen.Radix Codonopsis has strengthening spleen and tonifying lung, supports The effect of blood promotes the production of body fluid.It is usually used in spleen-lung Qi deficiency, eat less and tired, false asthma cough, the treatment of insufficiency of vital energy and blood etc., in being common simply Medicine.The processing method of traditional Radix Codonopsis is：It after medicinal material is excavated, directly dries/dries, bundle and package, storage and transportation.To after medicine materical crude slice factory, It washs, soften, be sliced, dry, pack again.Such medicine materical crude slice volume is big, and Hygienic Standard is poor, is easy to make moist, is mildew, infested, no Conducive to keeping, storage and transportation cost are high.In addition, such prepared slice quality stability is poor, clinical efficacy is difficult to ensure, clothes for patients With inconvenience, work slow.Therefore, develop a kind of stable quality is reliable, storage/transportation is at low cost, be conducive to keeping, carry and use Convenient, rapid-action novel Radix Codonopsis medicine materical crude slice, it is imperative.Existing market Radix Codonopsis medicine materical crude slice, other than traditional medicine materical crude slice, also ultra micro Two kinds of forms of powder medicine materical crude slice and concentrated granular medicine materical crude slice, but both using traditional medicine materical crude slice as raw material, quality is decided by traditional medicine materical crude slice Quality, and ultramicro decoction piece cannot solve the problems, such as medicinal material pollute；Concentrated granular can only extract water soluble ingredient.

Invention content

The invention discloses a kind of " Radix Codonopsis is fresh to carry freeze-drying granule pieces ", are primarily characterized in that：It is harvested in Radix Codonopsis Afterwards, it cleans in time, removal impurity and the dis-medicinal part such as silt, cleans in taking advantage of using fresh herb tap water in 24 hours and be cut into 2 ~ 5mm Thick piece.The piece that this cuts is added in the water of 1 ~ 5 times of 50 ~ 70 DEG C of weight, impregnate and is constantly stirred 5 ~ 30 minutes, filtering, medicine Slag presses extracting juice.The water that 5 ~ 10 times of weight is added in the gained dregs of a decoction is boiled 10 ~ 30 minutes, is filtered while hot, the dregs of a decoction squeeze again Juice collects concoction.Merge above-mentioned concoction, crosses 60 ~ 100 mesh sieve, be concentrated under reduced pressure, temperature is 50 ~ 75 DEG C, and being concentrated into relative density is 1.15 ~ 1.25 clear cream.This clear cream is left and taken to 0.5% ~ 3% spare, vacuum freeze drying again after -80 DEG C of remaining clear cream is freezed.It receives Collect lyophilized products, is mixed with particle with above-mentioned spare clear cream after crushing, then after drying, whole grain, packaging is got product.This drink The clinical general usage amount of piece is 1 ~ 5g, can both enter decoction decoction, take after mixing it with water, and also can directly enter pill, powder, capsule and tablet In, to substantially increase the convenience and compliance of Clinical practice, be conducive to the treatment of clinical acute disease.

The present invention solve traditional Radix Codonopsis medicine materical crude slice is bulky, carrying cost is high, be unfavorable for keeping, easily mildew it is infested, defend The shortcomings such as the poor, unstable quality of raw condition, due to being to take advantage of fresh extraction, quality is drunk than ultramicro grinding medicine materical crude slice and concentrated granular Piece is more preferable.

Specific embodiment

It after codonopsis pilosula is harvested, cleans, removes impurity and the dis-medicinal parts such as silt, using fresh herb is taken advantage of in 6 hours originally Water is cleaned, and is cut into the piece of 3mm thickness.This piece is added to 70 DEG C of pure water of 5 times of weight, is stirred 30 minutes, filtering, dregs of a decoction pressure Extracting juice.The pure water for adding 8 times of weight into the above-mentioned dregs of a decoction again is boiled 20 minutes and is extracted, filters while hot, the dregs of a decoction are again It squeezes the juice, collects concoction.Merge above-mentioned concoction, be concentrated under reduced pressure, temperature be set as 70 DEG C, be concentrated into relative density be 1.20 it is clear Cream.This clear cream is left and taken to 2% spare, vacuum freeze drying again after -80 DEG C of remaining clear cream is freezed.Collect lyophilized products, after crushing with it is upper It states spare clear cream and is mixed with particle, then after drying, whole grain, vacuum packaging is got product.

Claims

1. a kind of Radix Codonopsis is fresh to carry freeze-drying granule pieces, it is primarily characterized in that：After codonopsis pilosula harvesting, clean in time, Impurity and the dis-medicinal part such as silt are removed, medicinal material surface wettability is kept, cleans in taking advantage of using fresh herb tap water in 24 hours and is cut into 2 The water of 1 ~ 5 times of 50 ~ 70 DEG C of weight is added in the piece of ~ 5mm thickness, impregnates and constantly stirs 5 ~ 30 minutes, filtering, dregs pressing takes juice； The water that 5 ~ 10 times of weight is added in the gained dregs of a decoction is boiled 10 ~ 30 minutes, is filtered while hot, and the dregs of a decoction are squeezed the juice again, collects concoction； Merge above-mentioned concoction, cross 60 ~ 100 mesh sieve, be concentrated under reduced pressure, temperature is 50 ~ 75 DEG C, and it is 1.15 ~ 1.25 to be concentrated into relative density Clear cream；This clear cream is left and taken 0.5% ~ 3% spare, remaining clear cream freezes rear vacuum freeze drying；Lyophilized products are collected, and it is above-mentioned spare Clear cream be mixed with particle, after drying, whole grain, packaging is got product.

2. Radix Codonopsis according to claim 1 is fresh to carry freeze-drying granule pieces, it is primarily characterized in that：Clinic generally uses Amount is 1 ~ 5g, can both enter decoction decoction, take after mixing it with water, and also can directly enter in pill, powder, capsule and tablet.