CN108635291A - Beautifying liquid and preparation method thereof based on plant small molecular peptide - Google Patents
Beautifying liquid and preparation method thereof based on plant small molecular peptide Download PDFInfo
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Abstract
The present invention relates to a kind of beautifying liquid and preparation method thereof based on plant small molecular peptide, belongs to cosmetic technical field.The beautifying liquid is formed by the Raw material processing of following parts by weight：25 35 parts of aloe gel, 24 parts of linseed, 0.5 1.0 parts of Fatsia japonica seed oil, 46 parts of Poria cocos, 0.5 1.5 parts of the stem of noble dendrobium, 0.5 1.5 parts of ginseng, 0.5 1.5 parts of pearl powder, 13 parts of glucose, 50 60 parts of deionized water, 0.2 0.6 parts of food yeast, 0.5 0.8 parts of glutathione.Present invention application zymotechnique is from aloe, linseed, the stem of noble dendrobium, Fu a kind of reed mentioned in ancient books, and active ingredient is extracted in pearl powder, and by precipitation, transparent limpid beautifying liquid is made in initial filter, refined filtration technique, has whitening, nti-freckle, smoothing wrinkle, moisturizing, the tender skin of Firm, the effects that delaying senility.2, the micromolecule polypeptide protein techniques after present invention application enzymolysis are used for beauty, and whole cosmetic result is 35 times of the monomeric protein of chemical extraction.
Description
Technical field
The present invention relates to a kind of beautifying liquid and preparation method thereof based on plant small molecular peptide belongs to cosmetic art neck
Domain.
Background technology
The aging course of human skin and the degree of aging and residing environment, age and the mood of people are closely related.With
The growth at age, the variation and stimulation of outside climatic environment cause the sebaceous glands of skin and sweat gland secretion abnormal, to cause
Small pox.And with advancing age, the sebum of human body, moisture secretion can gradually decrease, the gradual aging of skin of people, sebum secretion
It reduces, the ability of vitrification moisture can decline, and to make skin become more and more dry, the cuticula of skin epidermis thickens, production
Rawhide skin keratinization, dry and cracked, skin surface just become more coarse, and resistance can also weaken, and bacterium intrusion causes dermopathic
Occur.
Due to the injury different degrees of to Skin Cell of chemical beauty product, International Cosmetic scientific research chemically synthesizing by
Step turns to pure plant extraction, and more stringent requirements are proposed to beauty product by people with the improvement of living standards, safety, day
So, efficiently.The present invention provides a kind of beautifying liquid and preparation method thereof based on plant small molecular peptide.
Invention content
It is an object of the present invention to solving the deficiencies in the prior art, a kind of beauty based on plant small molecular peptide is provided
Liquid.
The second object of the present invention is solution the deficiencies in the prior art, provides a kind of beauty based on plant small molecular peptide
The preparation method of liquid.
The technical solution adopted by the present invention to solve the technical problems is：
A kind of beautifying liquid based on plant small molecular peptide, the beautifying liquid are formed by the Raw material processing of following parts by weight：
25-35 parts of aloe gel, 2-4 parts of linseed, 0.5-1.0 parts of Fatsia japonica seed oil, 4-6 parts of Poria cocos, stem of noble dendrobium 0.5-1.5
Part, 0.5-1.5 parts of ginseng, 0.5-1.5 parts of pearl powder, 1-3 parts of glucose, 50-60 parts of deionized water, food yeast 0.2-0.6
Part, 0.5-0.8 parts of glutathione.
Preferably, the beautifying liquid is formed by the Raw material processing of following parts by weight：
30 parts of aloe gel, 3 parts of linseed, 0.75 part of Fatsia japonica seed oil, 5 parts of Poria cocos, 1 part of the stem of noble dendrobium, 1 part of ginseng, pearl powder 1
Part, 2 parts of glucose, 55 parts of deionized water, 0.5 part of food yeast, 0.6 part of glutathione.
Preferably, the preparation method of the Fatsia japonica seed oil is as follows：
S1：Fatsia japonica seed obtains Fatsia japonica seed powder after sorting, decladding, drying, crushing, being screened to 40~60 mesh；
S2:According to Fatsia japonica seed silty amount：Extraction solvent volume is 1：（5-6）The solid-liquid ratio of g/ml is into Fatsia japonica seed powder
Extraction solvent is added；
S3：Sonication assisted treatment, 40-50 DEG C for the treatment of temperature, processing time 25-40min, then decompression filters, concentration is made
Fatsia japonica seed oil.
Preferably, in the step S2, Extraction solvent is any one in n-hexane, petroleum ether, acetone and absolute ethyl alcohol
Kind, in the step S3,220~400W of power of Sonication assisted treatment.
Preferably, the glutathione is handled through incomplete oxidation, and oxidized form of glutathione accounts for 20-50 parts after processing, remaining
Amount is reduced glutathione.
Preferably, the processing method of the glutathione incomplete oxidation processing is as follows：Reduced glutathione is taken, in
45-55 DEG C of dissolving, obtains the reduced glutathione solution of 50-60g/L, and it is A1 to survey its pH value；With barium hydroxide tune pH to A2,
7.0≤A2≤7.1；A certain amount of hydrogen peroxide is added, it is stirring while adding, continue to be stirred to react 0.2-0.3h after adding；Reaction terminates
Afterwards, a certain amount of manganese dioxide is added, stirs 5-10min, then fully filters off manganese dioxide；With sulphur acid for adjusting pH to A3, A1-
0.05≤A3≤A1；Barium sulfate precipitate is fully filtered off, spray drying obtains incomplete oxidation treated reduced form gluathione
Peptide.
A kind of preparation method of the beautifying liquid based on plant small molecular peptide, steps are as follows for the method：
（1）The linseed of formula ratio, Poria cocos, the stem of noble dendrobium, ginseng, pearl powder are crushed, with the aloe gel of formula ratio, glucose,
Deionized water and food yeast are uniformly mixed in installation for fermenting；
（2）It is sealed by fermentation, the temperature for controlling fermentation is 25-30 DEG C, time 48-72h；
（3）Material after fermentation is separated by solid-liquid separation, zymotic fluid is left and taken；
（4）The zymotic fluid is uniformly mixed with the Fatsia japonica seed oil and glutathione of formula ratio, further filtering, sterilizing obtains
Obtain beautifying liquid finished product.
Preferably, the step（2）The bacteriostatic agent of zymotic fluid quality 0.2-0.3% is also added before middle sealing and fermenting, it is described
Bacteriostatic agent is bee glue powder.
Various materials have the following effects that in technical solution of the present invention：
Aloe：Containing a large amount of amino acid, vitamin, polysaccharide compound has bactericidal antiphlogistic, enhances immune function, removes
The effect of endotoxin and free radical makes skin contraction, softness, moisturizing, the performances such as whitening, also releasing hardening, angling, improvement
Scar prevents wrinkle, cutis laxa, moreover it is possible to keep skin wet.
The stem of noble dendrobium：Main component has polysaccharide, and amino acid, polyphenol compound, trace element has anti-aging, anti-oxidant, beautiful
The effects that appearance beauty treatment, toxin expelling skin care.
Linseed：Rich in unsaturated fatty acid and vitamin E, A, B, D, K, F etc., keep skin tender and glossy.
Poria cocos：Containing protein, lecithin, the active ingredients such as pachymaran have nti-freckle, anti-acne, whitening moisturizing etc.
Beauty functions.
Ginseng：It containing panaxoside and panaxan, promotes blood circulation, prevents skin ageing from being generated with wrinkle, simultaneously
Immune function can also be improved, prevent skin from receiving the destructive stimulus of external environment, accelerate cell metabolism, prevent it is dry and old
Change.
Pearl powder：Contain abundant trace element, leucine, methionine, 18 kinds of amino acid such as alanine, with whitening shield
Skin smoothes away wrinkles, the bright and clean effect of skin.
Fatsia japonica is Araliaceae Fatsia evergreen shrubs, and root, leaf, flower and seed all have certain medicinal valence
Value, many scholars study ingredient therein and its extraction process.The present invention extracts the Fatsia japonica seed oil obtained
Acid value（KOH）2.88mg/g is less than 3.00 mg/g；Peroxide value 6.63mmol/kg；Iodine number 97.23g/100g belongs to non-dry
Property oil, Fatsia japonica seed oil degree of unsaturation is relatively low；Relative density 0.8928, obtained Fatsia japonica seed oil are clear
Light yellow liquid, meet the standard of edible oil, it is healthy and safe.Fatsia japonica seed oil fatty acid composition and content are divided
Analysis, detects 15 kinds of aliphatic acid altogether in Fatsia japonica seed oil, and main component is oleic acid, linoleic acid, cis- 10- pentadecylenic acids, hard
Resin acid, especially based on oleic acid.Oleic acid antioxidative stabilizer is good, helps to improve the antioxidative stabilizer of beautifying liquid, in addition oozes
It penetrates in capillary of skin, can promote to soften blood vessel, reduce low density lipoprotein cholesterol content in blood of human body, improve
The effect of skin elasticity and color and luster.
The invention has the advantages that：
1, the present invention is using zymotechnique from aloe, and linseed, the stem of noble dendrobium, Fu a kind of reed mentioned in ancient books extracts active ingredient in pearl powder, by heavy
It forms sediment, transparent limpid beautifying liquid is made in initial filter, refined filtration technique, has a whitening, nti-freckle, smoothing wrinkle, moisturizing, the tender skin of Firm, and delay declines
The effect of waiting for a long time.
2, the micromolecule polypeptide protein techniques after present invention application enzymolysis are used for beauty, and whole cosmetic result is that chemistry carries
3-5 times of the monomeric protein taken.
3, plant small molecular peptide beautifying liquid finds that its resultant effect is international the most frequently used in antityrosinase activity experiment
8-10 times of whitening additive ursin recommended dose, be 3-5 times of kojic acid recommended dose, be 6-8 times of VC recommended doses
Left and right, is 7-10 times of glutathione external application recommended dose, is 5-7 times of licoflavone recommended dose.
4, in wounds in animals face spraying plant small molecular peptide beautifying liquid it was found that, can play the same similar to antibiotic
Thus antibacterial and anti-inflammatory effects illustrate protective effect of the plant small molecular peptide to skin.
5, the test of skin anti-uv-ray is respectively wiped out 5 cm diameter hairs in two sides of same animal bodies and is appeared
There is notable difference after irradiating 5 days in skin, daily intermittence ultraviolet light, and pigment intensification occurs in the skin for not spraying beautifying liquid,
And the skin for spraying beautifying liquid has almost no change, and illustrates that plant small molecular peptide has stronger anti-uv-ray.
Specific implementation mode
Below by specific embodiment, technical scheme of the present invention will be further explained in detail.
Embodiment 1：
A kind of beautifying liquid based on plant small molecular peptide, the beautifying liquid are formed by the Raw material processing of following parts by weight：
25 parts of aloe gel, 2 parts of linseed, 0.5 part of Fatsia japonica seed oil, 4 parts of Poria cocos, 0.5 part of the stem of noble dendrobium, 0.5 part of ginseng, pearl
0.5 part of powder, 1 part of glucose, 50 parts of deionized water, 0.2 part of food yeast, 0.5 part of glutathione；
The preparation method of the Fatsia japonica seed oil is as follows：
S1：Fatsia japonica seed obtains Fatsia japonica seed powder after sorting, decladding, drying, crushing, being screened to 40 mesh；
S2:According to Fatsia japonica seed silty amount：Extraction solvent volume is 1：5（g/ml）Solid-liquid ratio into Fatsia japonica seed powder plus
Enter Extraction solvent；
S3：Sonication assisted treatment, 40 DEG C, processing time 25min for the treatment of temperature, then decompression filters, octagonal gold is made in concentration
Disk seed oil.
Specifically, in the step S2, Extraction solvent is absolute ethyl alcohol, in the step S3, Sonication assisted treatment
Power 220W.
In the present invention, the glutathione is handled through incomplete oxidation, and oxidized form of glutathione accounts for 20 parts after processing, surplus
For reduced glutathione.The processing method of the glutathione incomplete oxidation processing is as follows：Reduced glutathione is taken, in
45 DEG C of dissolvings, obtain the reduced glutathione solution of 50g/L, and it is A1 to survey its pH value；With barium hydroxide tune pH to A2,7.0≤
A2≤7.1；A certain amount of hydrogen peroxide is added, it is stirring while adding, continue to be stirred to react 0.2h after adding；After reaction, it is added one
Quantitative manganese dioxide, stirs 5min, then fully filters off manganese dioxide；With sulphur acid for adjusting pH to A3, A1-0.05≤A3≤A1；
Barium sulfate precipitate is fully filtered off, spray drying obtains incomplete oxidation treated reduced glutathione.
The preparation method of the beautifying liquid based on plant small molecular peptide of the present invention, steps are as follows for the method：
（1）The linseed of formula ratio, Poria cocos, the stem of noble dendrobium, ginseng, pearl powder are crushed, with the aloe gel of formula ratio, glucose,
Deionized water and food yeast are uniformly mixed in installation for fermenting；
（2）It is sealed by fermentation, the temperature for controlling fermentation is 25 DEG C, time 72h；
（3）Material after fermentation is separated by solid-liquid separation, zymotic fluid is left and taken；
（4）The zymotic fluid is uniformly mixed with the Fatsia japonica seed oil and glutathione of formula ratio, further filtering, sterilizing obtains
Obtain beautifying liquid finished product, the step（2）The bacteriostatic agent of zymotic fluid quality 0.2, the bacteriostatic agent are also added before middle sealing and fermenting
For bee glue powder.
Embodiment 2：
A kind of beautifying liquid based on plant small molecular peptide, the beautifying liquid are formed by the Raw material processing of following parts by weight：
35 parts of aloe gel, 4 parts of linseed, 1.0 parts of Fatsia japonica seed oil, 6 parts of Poria cocos, 1.5 parts of the stem of noble dendrobium, 1.5 parts of ginseng, pearl
1.5 parts of powder, 3 parts of glucose, 60 parts of deionized water, 0.6 part of food yeast, 0.8 part of glutathione；
The preparation method of the Fatsia japonica seed oil is as follows：
S1：Fatsia japonica seed obtains Fatsia japonica seed powder after sorting, decladding, drying, crushing, being screened to 60 mesh；
S2:According to Fatsia japonica seed silty amount：Extraction solvent volume is 1：6（g/ml）Solid-liquid ratio into Fatsia japonica seed powder plus
Enter Extraction solvent；
S3：Sonication assisted treatment, 50 DEG C, processing time 40min for the treatment of temperature, then decompression filters, octagonal gold is made in concentration
Disk seed oil.
Specifically, in the step S2, Extraction solvent is n-hexane, in the step S3, Sonication assisted treatment
Power 400W.
In the present invention, the glutathione is handled through incomplete oxidation, and oxidized form of glutathione accounts for 50 parts after processing, surplus
For reduced glutathione.The processing method of the glutathione incomplete oxidation processing is as follows：Reduced glutathione is taken, in
55 DEG C of dissolvings, obtain the reduced glutathione solution of 60g/L, and it is A1 to survey its pH value；With barium hydroxide tune pH to A2,7.0≤
A2≤7.1；A certain amount of hydrogen peroxide is added, it is stirring while adding, continue to be stirred to react 0.2-0.3h after adding；After reaction, add
Enter a certain amount of manganese dioxide, stir 5-10min, then fully filters off manganese dioxide；With sulphur acid for adjusting pH to A3, A1-0.05≤
A3≤A1；Barium sulfate precipitate is fully filtered off, spray drying obtains incomplete oxidation treated reduced glutathione.
The preparation method of the beautifying liquid based on plant small molecular peptide of the present invention, steps are as follows for the method：
（1）The linseed of formula ratio, Poria cocos, the stem of noble dendrobium, ginseng, pearl powder are crushed, with the aloe gel of formula ratio, glucose,
Deionized water and food yeast are uniformly mixed in installation for fermenting；
（2）It is sealed by fermentation, the temperature for controlling fermentation is 30 DEG C, time 48h；
（3）Material after fermentation is separated by solid-liquid separation, zymotic fluid is left and taken；
（4）The zymotic fluid is uniformly mixed with the Fatsia japonica seed oil and glutathione of formula ratio, further filtering, sterilizing obtains
Obtain beautifying liquid finished product, the step（2）The bacteriostatic agent of zymotic fluid quality 0.3%, the bacteriostatic agent are also added before middle sealing and fermenting
For bee glue powder.
Embodiment 3：
A kind of beautifying liquid based on plant small molecular peptide, the beautifying liquid are formed by the Raw material processing of following parts by weight：
30 parts of aloe gel, 3 parts of linseed, 0.75 part of Fatsia japonica seed oil, 5 parts of Poria cocos, 1 part of the stem of noble dendrobium, 1 part of ginseng, pearl powder 1
Part, 2 parts of glucose, 55 parts of deionized water, 0.5 part of food yeast, 0.6 part of glutathione；
The preparation method of the Fatsia japonica seed oil is as follows：
S1：Fatsia japonica seed obtains Fatsia japonica seed powder after sorting, decladding, drying, crushing, being screened to 50 mesh；
S2:According to Fatsia japonica seed silty amount：Extraction solvent volume is 2：11（g/ml）Solid-liquid ratio into Fatsia japonica seed powder
Extraction solvent is added；
S3：Sonication assisted treatment, 45 DEG C, processing time 30min for the treatment of temperature, then decompression filters, octagonal gold is made in concentration
Disk seed oil.
Specifically, in the step S2, Extraction solvent is in absolute ethyl alcohol, in the step S3, at ultrasonic wave auxiliary
The power 320W of reason.
In the present invention, the glutathione is handled through incomplete oxidation, and oxidized form of glutathione accounts for 30 parts after processing, surplus
For reduced glutathione.The processing method of the glutathione incomplete oxidation processing is as follows：Reduced glutathione is taken, in
50 DEG C of dissolvings, obtain the reduced glutathione solution of 55g/L, and it is A1 to survey its pH value；With barium hydroxide tune pH to A2,7.0≤
A2≤7.1；A certain amount of hydrogen peroxide is added, it is stirring while adding, continue to be stirred to react 0.2-0.3h after adding；After reaction, add
Enter a certain amount of manganese dioxide, stir 5-10min, then fully filters off manganese dioxide；With sulphur acid for adjusting pH to A3, A1-0.05≤
A3≤A1；Barium sulfate precipitate is fully filtered off, spray drying obtains incomplete oxidation treated reduced glutathione.
The preparation method of the beautifying liquid based on plant small molecular peptide of the present invention, steps are as follows for the method：
（1）The linseed of formula ratio, Poria cocos, the stem of noble dendrobium, ginseng, pearl powder are crushed, with the aloe gel of formula ratio, glucose,
Deionized water and food yeast are uniformly mixed in installation for fermenting；
（2）It is sealed by fermentation, the temperature for controlling fermentation is 28 DEG C, time 60h；
（3）Material after fermentation is separated by solid-liquid separation, zymotic fluid is left and taken；
（4）The zymotic fluid is uniformly mixed with the Fatsia japonica seed oil and glutathione of formula ratio, further filtering, sterilizing obtains
Obtain beautifying liquid finished product, the step（2）The bacteriostatic agent of zymotic fluid quality 0.25% is also added before middle sealing and fermenting, it is described antibacterial
Agent is bee glue powder.
Above-mentioned embodiment is only a preferred solution of the present invention, not the present invention is made in any form
Limitation, on the premise of not exceeding the technical scheme recorded in the claims also other variations and modifications.
Claims (8)
1. a kind of beautifying liquid based on plant small molecular peptide, it is characterised in that：The beautifying liquid is added by the raw material of following parts by weight
Work forms：
25-35 parts of aloe gel, 2-4 parts of linseed, 0.5-1.0 parts of Fatsia japonica seed oil, 4-6 parts of Poria cocos, stem of noble dendrobium 0.5-1.5
Part, 0.5-1.5 parts of ginseng, 0.5-1.5 parts of pearl powder, 1-3 parts of glucose, 50-60 parts of deionized water, food yeast 0.2-0.6
Part, 0.5-0.8 parts of glutathione.
2. the beautifying liquid according to claim 1 based on plant small molecular peptide, it is characterised in that：The beautifying liquid is by following
The Raw material processing of parts by weight forms：
30 parts of aloe gel, 3 parts of linseed, 0.75 part of Fatsia japonica seed oil, 5 parts of Poria cocos, 1 part of the stem of noble dendrobium, 1 part of ginseng, pearl powder 1
Part, 2 parts of glucose, 55 parts of deionized water, 0.5 part of food yeast, 0.6 part of glutathione.
3. the beautifying liquid according to claim 1 or 2 based on plant small molecular peptide, it is characterised in that：The Fatsia japonica
The preparation method of seed oil is as follows：
S1：Fatsia japonica seed obtains Fatsia japonica seed powder after sorting, decladding, drying, crushing, being screened to 40~60 mesh；
S2:According to Fatsia japonica seed silty amount：Extraction solvent volume is 1：（5-6）The solid-liquid ratio of g/ml is into Fatsia japonica seed powder
Extraction solvent is added；
S3：Sonication assisted treatment, 40-50 DEG C for the treatment of temperature, processing time 25-40min, then decompression filters, concentration is made
Fatsia japonica seed oil.
4. the beautifying liquid according to claim 3 based on plant small molecular peptide, which is characterized in that in the step S2, extraction
Solvent is any one in n-hexane, petroleum ether, acetone and absolute ethyl alcohol, in the step S3, Sonication assisted treatment
220~400W of power.
5. the beautifying liquid according to claim 1 based on plant small molecular peptide, it is characterised in that：
The glutathione is handled through incomplete oxidation, and oxidized form of glutathione accounts for 20-50 parts after processing, and surplus is reduced form paddy
The sweet peptide of Guang.
6. the beautifying liquid according to claim 5 based on plant small molecular peptide, it is characterised in that：The glutathione is endless
The processing method of oxidized processing is as follows：Reduced glutathione is taken, in 45-55 DEG C of dissolving, obtains the reduced form of 50-60g/L
Glutathione solution, it is A1 to survey its pH value；With barium hydroxide tune pH to A2,7.0≤A2≤7.1；A certain amount of hydrogen peroxide, side is added
Edged stirs, and continues to be stirred to react 0.2-0.3h after adding；After reaction, a certain amount of manganese dioxide is added, stirs 5-
Then 10min fully filters off manganese dioxide；With sulphur acid for adjusting pH to A3, A1-0.05≤A3≤A1；It is heavy fully to filter off barium sulfate
It forms sediment, spray drying obtains incomplete oxidation treated reduced glutathione.
7. the preparation method of the beautifying liquid based on plant small molecular peptide, feature described in a kind of claim 1-6 any one exist
In：Steps are as follows for the method：
（1）The linseed of formula ratio, Poria cocos, the stem of noble dendrobium, ginseng, pearl powder are crushed, with the aloe gel of formula ratio, glucose,
Deionized water and food yeast are uniformly mixed in installation for fermenting；
（2）It is sealed by fermentation, the temperature for controlling fermentation is 25-30 DEG C, time 48-72h；
（3）Material after fermentation is separated by solid-liquid separation, zymotic fluid is left and taken；
（4）The zymotic fluid is uniformly mixed with the Fatsia japonica seed oil and glutathione of formula ratio, further filtering, sterilizing obtains
Obtain beautifying liquid finished product.
8. the preparation method of the beautifying liquid according to claim 1 based on plant small molecular peptide, it is characterised in that：The step
Suddenly（2）Also the bacteriostatic agent of addition zymotic fluid quality 0.2-0.3%, the bacteriostatic agent are bee glue powder before middle sealing and fermenting.
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| CN108635291B (en) | 2021-06-15 |
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