CN108627491A - A kind of time-resolved fluorescence detector - Google Patents
A kind of time-resolved fluorescence detector Download PDFInfo
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- CN108627491A CN108627491A CN201810730443.4A CN201810730443A CN108627491A CN 108627491 A CN108627491 A CN 108627491A CN 201810730443 A CN201810730443 A CN 201810730443A CN 108627491 A CN108627491 A CN 108627491A
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- pipette tips
- rifle fire
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- 238000011534 incubation Methods 0.000 claims abstract description 67
- 238000001514 detection method Methods 0.000 claims abstract description 58
- 230000033001 locomotion Effects 0.000 claims abstract description 36
- 239000003153 chemical reaction reagent Substances 0.000 claims description 226
- 230000003287 optical effect Effects 0.000 claims description 57
- 230000005540 biological transmission Effects 0.000 claims description 48
- 239000000758 substrate Substances 0.000 claims description 45
- 230000006835 compression Effects 0.000 claims description 28
- 238000007906 compression Methods 0.000 claims description 28
- 238000010009 beating Methods 0.000 claims description 23
- 230000003014 reinforcing effect Effects 0.000 claims description 22
- 210000004907 gland Anatomy 0.000 claims description 11
- 239000002699 waste material Substances 0.000 claims description 11
- 238000003825 pressing Methods 0.000 claims description 10
- 229910052724 xenon Inorganic materials 0.000 claims description 10
- FHNFHKCVQCLJFQ-UHFFFAOYSA-N xenon atom Chemical compound [Xe] FHNFHKCVQCLJFQ-UHFFFAOYSA-N 0.000 claims description 10
- 229920000742 Cotton Polymers 0.000 claims description 8
- 210000003205 muscle Anatomy 0.000 claims description 8
- 238000004321 preservation Methods 0.000 claims description 8
- 238000010438 heat treatment Methods 0.000 claims description 7
- 238000003860 storage Methods 0.000 claims description 7
- 239000003795 chemical substances by application Substances 0.000 claims description 6
- 238000005096 rolling process Methods 0.000 claims description 5
- 239000000463 material Substances 0.000 claims description 4
- 239000003381 stabilizer Substances 0.000 claims description 4
- 238000012544 monitoring process Methods 0.000 claims description 3
- NJPPVKZQTLUDBO-UHFFFAOYSA-N novaluron Chemical group C1=C(Cl)C(OC(F)(F)C(OC(F)(F)F)F)=CC=C1NC(=O)NC(=O)C1=C(F)C=CC=C1F NJPPVKZQTLUDBO-UHFFFAOYSA-N 0.000 claims description 3
- 230000000149 penetrating effect Effects 0.000 claims description 3
- 238000005728 strengthening Methods 0.000 claims description 2
- 210000002435 tendon Anatomy 0.000 claims description 2
- 238000000151 deposition Methods 0.000 claims 1
- 230000013011 mating Effects 0.000 claims 1
- 230000005622 photoelectricity Effects 0.000 claims 1
- 239000007787 solid Substances 0.000 claims 1
- 238000010586 diagram Methods 0.000 description 10
- 230000000694 effects Effects 0.000 description 3
- 238000005516 engineering process Methods 0.000 description 3
- 230000005611 electricity Effects 0.000 description 2
- 238000003756 stirring Methods 0.000 description 2
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 238000007689 inspection Methods 0.000 description 1
- 230000001788 irregular Effects 0.000 description 1
- 238000007885 magnetic separation Methods 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 238000002310 reflectometry Methods 0.000 description 1
- 238000005070 sampling Methods 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/01—Arrangements or apparatus for facilitating the optical investigation
Abstract
The present invention relates to medical treatment to test and analyze equipment technical field, specifically a kind of time-resolved fluorescence detector.The time-resolved fluorescence detector includes rack, movement, sample rack component, inhale cephali disc assembly and kit components, the movement, sample rack component, it inhales cephali disc assembly and kit components is set to the machine frame inside and is fixed on the machine frame inside, the sample rack component, it inhales cephali disc assembly and kit components is set to the outside of the movement, the movement includes sample arm, two incubation modules, volley of rifle fire arm and detection module, the lower section for incubating module and being set to the detection module and volley of rifle fire arm side by side, the sample arm is set to the sample rack component, inhale the top of cephali disc assembly and kit components, the lower section for incubating module is equipped with ash can.
Description
Technical field
The present invention relates to medical treatment to test and analyze equipment technical field, specifically a kind of time-resolved fluorescence detector.
Background technology
With the continuous development of science and technology, medical technology is also being continued to develop, and the detection of blood sample is always all
It is a highly important job.But the general volume of the instrument for pattern detection now is larger, cumbersome and work
Make it is extremely inefficient, therefore at this stage it is desirable that a kind of instrument for the detection that can effectively carry out sample meets need at this stage
It asks.
Invention content
It is glimmering that the present invention provides a kind of time resolution that can efficiently carry out the carrying of reagent sample, stirring, mixing and light detection
Optical detector.
The present invention is achieved through the following technical solutions：
A kind of time-resolved fluorescence detector, including rack, movement, sample rack component, suction cephali disc assembly and kit group
Part, the movement, inhale cephali disc assembly and kit components set on the machine frame inside and are fixed on the rack sample rack component
Inside, the sample rack component inhale cephali disc assembly and kit components set on the outside of the movement, and the movement includes sample-adding
Arm, two incubation modules, volley of rifle fire arm and detection module, the incubation module are set under the detection module and volley of rifle fire arm side by side
Side, the sample arm is under the top of the sample rack component, suction cephali disc assembly and kit components, the incubation module
Side is equipped with ash can, is enclosed with shell on the outside of the rack, the shell goes out equipped with display, consumptive material adding mouth and waste material
Mouthful, set that there are four stabilizer blades below the rack.
The sample arm includes the first X-motion component, the first Y-motion component, single rifle component and takes dozen component,
The first Y-motion component is connected on the first X-motion component, and in first X-motion
It is moved on component, the list rifle component and takes and beat component and be connected on the first Y-motion component, and described the
It is moved on one Y-motion component, the list rifle component includes sample arm rack, the first transmission component, the first driven subassembly
And single armed, first transmission component and first driven subassembly are set on the sample arm rack, the first transmission component
It is connected with the first transmission belt between first driven subassembly, the first fixed block is installed on first transmission belt, it is described
Single armed is connected on first fixed block, and the lower part of the single armed is equipped with suction nozzle detection set, described to take that beat component include institute
Sample arm rack is stated, the second transmission component, the second driven subassembly, reagent bar assembly is taken and beats reagent bar assembly, the sample arm
Rack is connected on the first Y-motion component, and second transmission component is connected to second driven subassembly
On the sample arm rack, it is driven band connection by second between second transmission component and second driven subassembly,
Described to take reagent bar assembly by taking reagent bar to be connected on second transmission belt, second transmission belt takes with described
The second fixed block is equipped between the top of reagent bar, it is described that reagent bar assembly is taken to be set to the lower part for taking reagent bar, institute
It states and reagent bar assembly is taken to include reagent strip righting module and take reagent stick, it is described that reagent stick is taken to be set to the reagent strip righting
The lower part of module, the reagent strip righting module include the first fixed plate, righting board, two righting compressed springs, two rightings
Compressed spring fixed block, two beat reagent strip head and two are played reagent strip head return spring, it is described beat reagent strip head pass through it is described
It righting compressed spring fixed block and the first fixed plate and is connected on the righting board, the righting compressed spring passes through institute
It states the first fixed plate and set between the righting compressed spring fixed block and righting board, the reagent bar assembly of beating includes beating
Reagent batten is located at the top for beating reagent strip head with reagent bar, the reagent batten of beating is broken.
The first X-motion component and the first Y-motion component include fixed plate, guide rail and Power Component,
Second fixed block is equipped with first baffle, and the top of the first baffle is equipped with the first photosensitive sensors, described to play reagent
Batten is equipped with second baffle, and the top of the second baffle is equipped with the second photosensitive sensors, the lower section for breaking reagent batten
Identifier is captured equipped with reagent strip, the top for beating reagent bar, which is connected with, beats reagent strip board motor.
The incubation module includes incubating frame, incubating module, three reagent strip tablettings and third Power Component, the incubation
Module is connected on the incubation frame, and three reagent strip tablettings are connected to the both sides for incubating frame, the reagent strip
Tabletting is located at the top for incubating module, and the third Power Component is mounted on the inside of the incubation frame, the incubation module
It is deposited in inside the incubation box including incubating box, reagent strip, suction nozzle and suction nozzle buffer area, the reagent strip, the suction nozzle is deposited
It is put in inside the suction nozzle buffer area, the outside of the suction nozzle buffer area is equipped with waste material push plate, and the waste material push plate is located at described
The inside of frame is incubated, the incubation box is internally provided with eight incubation blocks, and the incubation block is internally provided with incubation slot, the reagent
Item is deposited in inside the incubation slot, and the outside for incubating box, which is enclosed with, incubates block heat-preservation cotton, the lower part for incubating box
Equipped with heating plate pressing plate, the lower part of the heating plate pressing plate is equipped with lower incubation block heat-preservation cotton, and the suction nozzle buffer area is equipped with eight
Suction nozzle hole, the suction nozzle hole are internally provided with compression spring, and the compression spring top is equipped with compression spring gland, and the top of the compression spring gland is equipped with
Compression spring gland pressing plate, the reagent strip tabletting go out sample preformed groove equipped with eight reagents, and the incubation frame includes left socle, right branch
Frame, connection transverse slat, connection riser and connecting rod, the connection transverse slat, connection riser and connecting rod are set to the left socle and the right side
Between holder.
The bottom for incubating module, which is equipped with, incubates box support, and the left side for incubating box support is equipped with first leg, institute
It states and is set on the outside of first leg there are two scroll wheel, the middle part of the right support, which is equipped with, rolls race, and the scroll wheel is described
Race roll inside is rolled, the right side for incubating box support is equipped with the second supporting leg, and the inside of the left socle is equipped with transmission belt
Slot, is connected with third transmission belt between the incubation box support and the third Power Component, second supporting leg is connected to institute
It states on third transmission belt, right mounting is equipped on the inside of described rolling race, the inside of the transmission trough of belt is equipped with left mounting, described
The top of left socle is equipped with long guideway, and the incubation box support is mounted on the long guideway and free movement, the incubation
Box is mounted on the incubation box support.
The detection module includes the second X-motion component, the second Z-motion component and photodetector, described
Second Z-motion component is connected on the second X-motion component, and on the second X-motion component
Movement, the photodetector are connected on the second Z-motion component, and in the second Z-motion component
Upper movement, the second Z-motion component are equipped with rotary electric machine, and the rotary electric machine is equipped with cam, the light detection
Component is equipped with rotating wheel, and the cam rotation drives the rotating wheel rotation, drives the photodetector to move up and down, institute
It states and is equipped with Z tension springs between the second Z-motion component and the photodetector, the photodetector includes xenon lamp, light
Pedestal, light path and photomultiplier are learned, the photomultiplier is set to the top of the optical substrate, and the xenon lamp is set to
The left side of the optical substrate, the light path are set to the inside of the optical substrate.
It is axially moved component and is equipped with cross slide way and the second Power Component, the second Z-motion component is described
It being moved on cross slide way, second Power Component drives the second Z-motion component to be moved on the cross slide way,
The second Z-motion component is equipped with vertical guide, and the photodetector moves in the vertical guide, the inspection
Survey light path include the first lens group, 340 optical filters, two to penetrate mirror, the second lens group, fitting ring, optical filter, 613/340 filter
Piece switch groups and the third lens group, first lens group and 340 optical filters are vertically set to inside the optical substrate, and described the
Two lens groups, fitting ring, optical filter, 613/340 optical filter switch groups and the third lens group are laterally set in the optical substrate
Portion, described two is oblique inside the optical substrate to 45 ° of mirror is penetrated.
First lens group, the second lens group and the third lens group are made of two pieces of planoconvex lens respectively, the optics base
It is equipped with optical filter switch motor positioned at the side of the photomultiplier on seat, the output end of the optical filter switch motor connects
On the 613/340 optical filter switch groups, the side of the xenon lamp is equipped with third photosensitive sensors, the optical filter switching
The top of motor is equipped with flying disc, and the flying disc turns over the third photosensitive sensor, and the lower part of the fitting ring is equipped with examination
Agent item, the reagent strip are equipped with circle detection hole, and the outer edge in the circle detection hole is equipped with the round darkening ring of a circle, institute
It states and forms card slot between circle detection hole and the round darkening ring, the bottom of the fitting ring is equipped with retainer ring, and the retainer ring is embedding
Enter inside the card slot.
Kit components include several reagent strips and kit, and the kit is U-shaped, and the kit inner ring is equipped with examination
Agent storage groove, the reagent strip are put in inside the reagent strip storage groove, and the reagent strip is elongated, the reagent strip
Left side is equipped with handle, and the middle part of the reagent strip is equipped with circle detection hole, and the right side in the circle detection hole is grabbed equipped with reagent strip
Take square hole, the lower section of the reagent strip crawl square hole is equipped with four clamping shrapnels, the clamping shrapnel be buckled in take reagent stick it
On, the inner wall on the left of the kit is equipped with two strip convex ribs, and the inner wall on the right side of the kit is equipped with three and half
Circular rib, sets that there are six oblong reagent wells, the left sides of the circle monitoring hole on the right side of reagent strip crawl square hole
If there are one circular through hole, the circular through hole is internally provided with an EUCUP, sets on the left of the EUCUP and is tried there are two round
Agent hole is set on the left of the circular reagent hole there are one short oval reagent wells, and the left side of the short oval reagent wells is equipped with
The outer edge of two rectangular reagent wells, the circle detection hole is equipped with the round darkening ring of a circle, the circle detection hole and institute
It states and forms card slot between round darkening ring, the card slot is for installing fitting ring.
The both sides of the circular through hole, circle detection hole and reagent strip crawl square hole are equipped with the first reinforcing rib, and the length is ellipse
The centre of circular reagent hole bottom is equipped with the second reinforcing rib, and muscle, the circle are kept flat equipped with one perpendicular to second reinforcing rib
The centre of shape reagent wells, short oval reagent wells and rectangular reagent wells bottom is equipped with third reinforcing rib, adds perpendicular to the third
Strengthening tendons be equipped with it is described keep flat muscle, the 4th reinforcing rib is equipped between two article of first reinforcing rib, on the upper surface of the reagent strip
Equipped with one layer of reagent diaphragm seal.
The volley of rifle fire arm includes volley of rifle fire base assembly, volley of rifle fire motor, pipette tips component and Magneto separate component, the volley of rifle fire motor
Set on the top of the volley of rifle fire base assembly, the pipette tips component is connected on the volley of rifle fire base assembly, the Magneto separate
Component is located at the lower part of the volley of rifle fire base assembly, and positioned at the lower section of the pipette tips component, and the volley of rifle fire base assembly includes
Volley of rifle fire substrate, volley of rifle fire motor fixing plate, pipette tips guide rail and pipette tips guide rail splice, the volley of rifle fire motor fixing plate are set to the row
The top of rifle substrate, the pipette tips guide rail are located on the volley of rifle fire substrate, and the pipette tips guide rail splice is mounted on the rifle
On head guide rail, the volley of rifle fire motor is mounted on the lower part of the volley of rifle fire motor fixing plate, and the right side of the pipette tips guide rail is equipped with
Volley of rifle fire lead screw, the volley of rifle fire lead screw are connected to by belt on the volley of rifle fire motor, and the pipette tips component is connected to the rifle
On head guide rail splice, the top of the pipette tips component is equipped with Z-direction feed screw nut, and the Z-direction feed screw nut is socketed in pipette tips
On lead screw.
The pipette tips component, which includes pipette tips clamping motor fixed plate, pipette tips fixed substrate, compresses lifting motor, the volley of rifle fire fixes
Plate and the volley of rifle fire, the pipette tips fixed substrate are connected on the pipette tips guide rail splice, the pipette tips clamping motor fixed plate
Set on the top of the pipette tips fixed substrate, the compression lifting motor is mounted on the pipette tips clamping motor fixed plate,
The volley of rifle fire fixed plate is connected on the pipette tips fixed substrate, and the volley of rifle fire is connected on the volley of rifle fire fixed plate, institute
The volley of rifle fire is stated equipped with suction nozzle detection set, the top of the volley of rifle fire is equipped with pipette tips piston motion block, and the volley of rifle fire is lived with the pipette tips
It is equipped with piston between plug moving mass and compresses guide rod and piston compression spring, the pipette tips clamping motor fixed plate fixes base with the pipette tips
Two briquetting guide rods and a piston clamping screw are equipped between plate, the pipette tips piston motion block is socketed in the briquetting guide rod
On piston clamping screw, the top of the piston clamping screw is connected with the compression lifting motor, and is connected by belt
It connects, the back side of the volley of rifle fire board unit is equipped with volley of rifle fire fixed plate and volley of rifle fire guide rail splice, and the Magneto separate component is equipped with
Four pipette tips slots, the pipette tips slot are internally provided with magnetic head, and the rear portion of the Magneto separate component passes through the volley of rifle fire base assembly
Equipped with Magneto separate component movement module.
Advantageous effect caused by the present invention is：
In the present invention, some chemical characteristics that sample itself is reacted by the light detection to sample, wherein by adding
It takes the module for beating reagent strip that reagent strip can be effectively carried to incubation inside modules on sample arm, similarly passes through sample arm
On single rifle module suction nozzle, sample etc. can be carried, the design of third volley of rifle fire arm can then be effectively performed in reagent strip
The stirring of the sample in portion works with mixing, its main feature is that the operation inside four reagent strips can be carried out at the same time, is greatly saved
Time, improve efficiency, the 4th the characteristics of incubating the movement of module so that can be moved after the sample mixing inside reagent strip
To carrying out light detection below detection module, while, the designs of two incubation modules greatly improve the efficiency of incubation, and one
A block that incubates can be carried out at the same time next incubation work for incubating block when being detected.
Description of the drawings
Below in conjunction with attached drawing, invention is further described in detail.
Fig. 1 is the stereogram of time-resolved fluorescence detector of the present invention.
Fig. 2 is the partial structural diagram of time-resolved fluorescence detector of the present invention.
Fig. 3 is the partial structural diagram of time-resolved fluorescence detector of the present invention.
Fig. 4 is reagent strip of the present invention and the structural schematic diagram of kit.
Fig. 5 is reagent strip of the present invention and the vertical view of kit.
Fig. 6 is the vertical view of reagent strip of the present invention.
Fig. 7 is the upward view of reagent strip of the present invention.
Fig. 8 is the side view of reagent strip of the present invention.
Fig. 9 is that single rifle of the present invention takes the structural schematic diagram for beating reagent strip device.
Figure 10 is that single rifle of the present invention takes the structural schematic diagram for beating reagent strip device.
Figure 11 is single rifle component of the present invention and takes the side view for beating component.
Figure 12 is single rifle component of the present invention and takes the stereogram for beating component.
Figure 13 is single rifle component of the present invention and takes the stereogram in another direction for beating component.
Figure 14 is single rifle component of the present invention and takes the sectional view for beating component.
Figure 15 is the structural schematic diagram of detection module of the present invention.
Figure 16 is the structural schematic diagram of detection module of the present invention.
Figure 17 is the partial cutaway view of detection module of the present invention.
Figure 18 is the vertical view of reagent strip of the present invention.
Figure 19 is suction nozzle buffer unit of the present invention and the structural schematic diagram of reagent strip tabletting.
Figure 20 is suction nozzle buffer unit of the present invention and the sectional view of reagent strip tabletting.
Figure 21 is the structural schematic diagram that text of the present invention is met.
Figure 22 is the right view of the present invention for incubating frame.
Figure 23 is the left view of the present invention for incubating frame.
Figure 24 is the sectional view of suction nozzle buffer area of the present invention.
Figure 25 is the structural schematic diagram of volley of rifle fire arm of the present invention.
Figure 26 is the true figure of volley of rifle fire arm of the present invention.
Figure 27 is the side view of volley of rifle fire arm of the present invention.
The corresponding label of component names is as follows in figure：
100, rack；101, reagent strip；102, kit；103, reagent strip storage groove；104, handle；105, circle detection
Hole；106, reagent strip captures square hole；107, shrapnel is clamped；108, strip convex ribs；109, semicircle convex ribs；110, oblong
Reagent wells；111, circular through hole；112、EUCUP；113, circular reagent hole；114, short oval reagent wells；115, rectangular reagent
Hole；116, round darkening ring；117, card slot；118, the first reinforcing rib；119, the second reinforcing rib；120, muscle is kept flat；121, third
Reinforcing rib；122, the 4th reinforcing rib；200, movement；201, the first X-motion component；202, the first Y-motion component；
203, single rifle component；204, it takes and beats component；205, sample arm rack；206, the first transmission component；207, the first driven subassembly；
208, single armed；209, the first transmission belt；210, the first fixed block；211, suction nozzle detection set；212, the second transmission component；213,
Two driven subassemblies；214, reagent bar assembly is taken；215, reagent bar assembly is beaten；216, the second transmission belt；217, reagent bar is taken；
218, the second fixed block；220, reagent stick is taken；221, the first fixed plate；222, righting board；223, righting compressed spring；224、
Righting compressed spring fixed block；225, reagent strip head is beaten；226, reagent strip head return spring is played；227, reagent batten is broken；228、
Beat reagent bar；229, fixed plate；230, guide rail；231, Power Component；232, first baffle；233, the first photosensitive sensors；
234, second baffle；235, the second photosensitive sensors；236, reagent strip captures identifier；237, reagent strip board motor is beaten；300、
Sample rack component, the 301, second X-motion component；302, the second Z-motion component；303, photodetector；304, turn
Dynamic motor；305, cam；306, rotating wheel；307, Z tension springs；308, xenon lamp；309, optical substrate；311, photomultiplier；
312, cross slide way；313, the second Power Component；314, vertical guide；315, the first lens group；316,340 optical filter；317、
Two to penetrating mirror；318, the second lens group；319, it is bonded ring；320, optical filter；321,613/340 optical filter switch groups；322,
Three lens groups；323, optical filter switch motor；324, third photosensitive sensors；325, flying disc；326, retainer ring；400, suction nozzle disk group
Part；401, frame is incubated；402, module is incubated；403, reagent strip tabletting；404, third Power Component；405, box is incubated；406, it inhales
Head；407, suction nozzle buffer area；408, waste material push plate；409, slot is incubated；410, upper incubation block heat-preservation cotton；411, heating plate pressing plate；
412, lower incubation block heat-preservation cotton；413, suction nozzle hole；414, compression spring；415, compression spring gland；416, compression spring gland pressing plate；417, reagent
Go out sample preformed groove；418, left socle；419, right support；420, transverse slat is connected；421, riser is connected；422, connecting rod；423, warm
Educate box support；424, first leg；425, scroll wheel；426, race is rolled；427, the second supporting leg；428, it is driven trough of belt；429、
Third transmission belt；430, right mounting；431, left mounting；432, long guideway；500, kit components；600, sample arm；601, it arranges
Rifle base assembly；602, volley of rifle fire motor；603, pipette tips component；604, Magneto separate component；605, volley of rifle fire substrate；606, volley of rifle fire motor
Fixed plate；607, pipette tips guide rail；608, pipette tips guide rail splice；609, volley of rifle fire lead screw；610, belt；611, Z-direction feed screw nut；
612, pipette tips clamping motor fixed plate；613, pipette tips fixed substrate；614, lifting motor is compressed；615, volley of rifle fire fixed plate；616、
The volley of rifle fire；617, pipette tips piston motion block；618, piston compresses guide rod；619, piston compression spring；620, briquetting guide rod；621, piston pressure
Tight lead screw；622, volley of rifle fire fixed plate；623, volley of rifle fire guide rail splice；624, pipette tips slot；625, magnetic head；626, Magneto separate component is transported
Dynamic model block；627, suction nozzle detection set；700, module is incubated；800, volley of rifle fire arm；900, detection module；1000, ash can；1100、
Shell；1200, display；1300, consumptive material adding mouth；1400, waste outlet；1500, stabilizer blade.
Specific implementation mode
The present invention is described in further detail with reference to the accompanying drawings and embodiments：
As the embodiment of time-resolved fluorescence detector of the present invention, as shown in Figure 1, Figure 2, Fig. 3, Fig. 4, Fig. 5, Fig. 6, figure
7, Fig. 8, Fig. 9, Figure 10, Figure 11, Figure 12, Figure 13, Figure 14, Figure 15, Figure 16, Figure 17, Figure 18, Figure 19, Figure 20, Figure 21, Figure 22, figure
23, shown in Figure 24, Figure 25, Figure 26 and Figure 27, including rack 100, movement 200, sample rack component 300,400 and of suction cephali disc assembly
Kit components 500, the movement 200, sample rack component 300 inhale cephali disc assembly 400 and kit components 500 set on described
100 inside of rack is simultaneously fixed on inside the rack 100, and the sample rack component 300 inhales cephali disc assembly 400 and kit group
Part 500 is set to the outside of the movement 200, and the movement 200 includes that sample arm 600, two incubates module 700, volley of rifle fire arm 800
With detection module 900, the incubation module 700 is set to the lower section of the detection module 900 and volley of rifle fire arm 800 side by side, described to add
The top that sample arm 600 is set to the sample rack component 300, inhales cephali disc assembly 400 and kit components 500, the incubation module
700 lower section is equipped with ash can 1000, and the outside of the rack 100 is enclosed with shell 1100, and the shell 1100 is equipped with aobvious
Show device 1200, consumptive material adding mouth 1300 and waste outlet 1400, the lower section of the rack 100 sets that there are four stabilizer blades 1500.
In the present embodiment, the sample arm 600 includes the first X-motion component 201, the first Y-motion component
202, it single rifle component 203 and takes and beats component 204, the first Y-motion component 202 is connected to first X-motion
It on component 201, and is moved on the first X-motion component 201, the list rifle component 203 and takes and beat component 204
It is connected to 202 on the first Y-motion component, and is moved on the first Y-motion component 202, this
The motion mode of kind enables single rifle that dozen reagent strip device is taken to be moved in three circumferential directions, the list rifle component
203 include sample arm rack 205, the first transmission component 206, the first driven subassembly 207 and single armed 208, first transmission group
Part 206 and first driven subassembly 207 are set on the sample arm rack 205, the first transmission component 206 and described first
It is connected with the first transmission belt 209 between driven subassembly 207, the first fixed block 210, institute are installed on first transmission belt 209
It states single armed 208 to be connected on first fixed block 210, the lower part of the single armed 208 is equipped with suction nozzle detection set 211, herein
Single armed Z axis to movement, solve the problems, such as upper and lower vertical sampling, be loaded, mix thoroughly so that it is such list rifle take beat reagent strip
Device more can complete efficiently and directly task, described that dozen component 204 is taken to include the sample arm rack 205, second
Transmission component 212, the second driven subassembly 213 take reagent bar assembly 214 and beat reagent bar assembly 215, the sample arm rack
205 are connected on the first Y-motion component 201, second transmission component 212 and second driven subassembly
213 are connected on the sample arm rack 205, lead between second transmission component 212 and second driven subassembly 213
The connection of the second transmission belt 216 is crossed, it is described to take reagent bar assembly 214 by taking reagent bar 217 to be connected to second transmission belt
On 216, the second fixed block 218 is equipped between second transmission belt 216 and the top for taking reagent bar 217, it is described
Reagent bar assembly 214 is taken to be set to the lower part for taking reagent bar 217, it is described that reagent bar assembly 214 is taken to include reagent strip righting
Module and take reagent stick 220, the lower part for taking reagent stick 220 to be set to the reagent strip righting module, the reagent strip
Righting module is fixed including the first fixed plate 221, the righting compressed spring of righting compressed spring 223, two of righting board 222, two
Block 224, two beats reagent strip head 225 and two are played reagent strip head return spring 226, and the reagent strip head 225 of beating is across described
It righting compressed spring fixed block 224 and the first fixed plate 221 and is connected on the righting board 222, the righting compression
Spring 223 is across first fixed plate 221 and is set to the righting compressed spring fixed block 224 and righting board 222,
The reagent bar assembly 215 of beating includes breaking reagent batten 227 and beating reagent bar 228, and the reagent batten 227 of beating is positioned at described
The top of reagent strip head 225 is beaten, operation principle herein is, described to take reagent stick 220 after stretching into reagent strip, clamps examination
Agent item, while the upper surface of reagent strip is contacted with the lower surface of first fixed plate 221, it ensure that the level of reagent strip
And it will not tilt or tip over, then break reagent batten 227 by described after being carried to reagent strip inside incubation slot
Effect, the reagent strip head 225 of beating is beaten down, so that reagent strip is fallen off on reagent stick 220 from taking, reagent is played in completion
The work of item.
In the present embodiment, the first X-motion component 201 and the first Y-motion component 202 include fixed plate
229, guide rail 230 and Power Component 231, second fixed block 218 are equipped with first baffle 232, the first baffle 232
Top is equipped with the first photosensitive sensors 233, and the reagent batten 227 of beating is equipped with second baffle 234, the second baffle 234
Top be equipped with the second photosensitive sensors 235, the lower section for breaking reagent batten 227 be equipped with reagent strip capture identifier 236, this
The design at place solves the problems, such as it is after taking reagent strip and playing reagent strip completion, for the progress that guarantees effectively to stop
Operation, complete to stop operation by the interruption of signal, the top for beating reagent bar 228, which is connected with, beats reagent batten electricity
Machine 237.
In the present embodiment, the incubation module 700 includes incubating frame 401, incubating 402, three reagent strip tablettings 403 of module
With third Power Component 404, the incubation module 402 is connected on the incubation frame 401, three reagent strip tablettings
403 are connected to the both sides for incubating frame 401, and the reagent strip tabletting 403 is located at the top for incubating module 402, described
Third Power Component 404 is mounted on 401 inside of the incubation frame, and the incubation module 402 includes incubating box 405, reagent strip
101, suction nozzle 406 and suction nozzle buffer area 407, the reagent strip 101 are deposited in inside the incubation box 405, and the suction nozzle 406 is deposited
It is put in inside the suction nozzle buffer area 407, the outside of the suction nozzle buffer area 407 is equipped with waste material push plate 408, the waste material push plate
408 are located at the inside for incubating frame 401, and the eight incubation blocks that are internally provided with for incubating box 405 are set inside the incubation block
Have and incubate slot 409, the reagent strip 101 is deposited in inside the incubation slot 409, and the outside for incubating box 405 is enclosed with
Block heat-preservation cotton 410 is incubated, the lower part for incubating box 405 is equipped with heating plate pressing plate 411, the lower part of the heating plate pressing plate 411
Equipped with lower incubation block heat-preservation cotton 412, the suction nozzle buffer area 407 is equipped with eight suction nozzle holes 413, is set inside the suction nozzle hole 413
There are compression spring 414,414 top of the compression spring to be equipped with compression spring gland 415, the top of the compression spring gland 415 is equipped with compression spring gland pressure
Plate 416, the reagent strip tabletting 403 go out sample preformed groove 417 equipped with eight reagents, and the incubation frame 401 includes left socle
418, right support 419, connection transverse slat 420, connection riser 421 and connecting rod 422, the connection transverse slat 420, connection riser 421
And connecting rod 422 is set between the left socle 418 and right support 419.
In the present embodiment, the bottom for incubating module 402, which is equipped with, incubates box support 423, the incubation box support 423
Left side is equipped with first leg 424, and the outside of the first leg 424 is set there are two scroll wheel 425, in the right support 419
Portion, which is equipped with, rolls race 426, the scroll wheel 425 in 426 roll inside of rollings race, the incubation box support 423
Right side is equipped with the second supporting leg 427, and the inside of the left socle 418 is equipped with transmission trough of belt 428, the incubation box support 423 and institute
It states and is connected with third transmission belt 429 between third Power Component 404, second supporting leg 427 is connected to the third transmission belt
On 429,426 inside of described rolling race is equipped with right mounting 430, and the inside of the transmission trough of belt 428 is equipped with left mounting 431,
The top of the left socle 418 is equipped with long guideway 432, and the incubation box support 423 is mounted on the long guideway 432 simultaneously certainly
By moving, the incubation box 405 is mounted on the incubation box support 423.
In the present embodiment, the detection module 900 includes the second X-motion component 301, the second Z-motion component
302 and photodetector 303, the second Z-motion component 302 be connected to the second X-motion component 301 it
On, and moved on the second X-motion component 301, the photodetector 303 is connected to second Z axis to fortune
It on dynamic component 302, and moves on the second Z-motion component 302, is set on the second Z-motion component 302
There are rotary electric machine 304, the rotary electric machine 304 to be equipped with cam 305, the photodetector 303 is equipped with rotating wheel 306,
The rotation of the cam 305 drives the rotating wheel 306 to rotate, and drives the photodetector 303 to move up and down, the 2nd Z
It is axially moved between component 302 and the photodetector 303 and is equipped with Z tension springs 307, the photodetector 303 includes xenon
Lamp 308, optical substrate 309, light path and photomultiplier 311, the photomultiplier 311 are set to the optical substrate
309 top, the xenon lamp 308 are set to the left side of the optical substrate 309, and the light path is set to the optical substrate
309 inside.
In the present embodiment, the second X-motion component 301 is equipped with cross slide way 312 and the second Power Component
313, the second Z-motion component 302 moves on the cross slide way 312, and second Power Component 313 drives institute
It states the second Z-motion component 302 to move on the cross slide way 312, the second Z-motion component 302 is equipped with
Vertical guide 314, the photodetector 303 move in the vertical guide 314, and the light path includes the first lens
315,340 optical filters 316, two of group filter to mirror 317, the second lens group 318, fitting ring 319, optical filter 320,613/340 is penetrated
Piece switch groups 321 and the third lens group 322, first lens group, 315 and 340 optical filter 316 are vertically set to the optics base
Inside seat 309, second lens group 318, fitting ring 319, optical filter 320,613/340 optical filter switch groups 321 and third
Lens group 322 is laterally set to inside the optical substrate 309, and described two are set to the optics base to 317 oblique 45 ° of inclination angles of mirror are penetrated
Inside seat 309.
In the present embodiment, first lens group 315, the second lens group 318 and the third lens group 322 are flat by two pieces respectively
Convex lens forms, the design of two pieces of planoconvex lens so that irregular light can vertically project after entering lens group, the light
The side for being located at the photomultiplier 311 on pedestal 309 is learned equipped with optical filter switch motor 323, the optical filter switching electricity
The output end of machine 323 is connected on the 613/340 optical filter switch groups 321, design herein so that in the optics base
The 613/340 optical filter switch groups 321 inside seat 309 can switch between 613 optical filters and 340 optical filters, to
The detection of two different reflectivity is carried out, the side of the xenon lamp 308 is equipped with third photosensitive sensors 324, the optical filter
The top of switch motor 323 is equipped with flying disc 325, and the flying disc 325 turns over the third photosensitive sensor 324, leads to herein
Effect of the flying disc 325 inside the third photosensitive sensor 324 is crossed, is played between 613 optical filters and 340 optical filters
The lower part of switching, the fitting ring 319 is equipped with reagent strip 101, and the reagent strip 101 is equipped with circle detection hole 105, the circle
The outer edge of shape detection hole 105 is equipped with the round darkening ring 116 of a circle, the circle detection hole 105 and the round darkening ring
Card slot 117 is formed between 116, the bottom of the fitting ring 319 is equipped with retainer ring 326, and the retainer ring 326 is embedded in the card slot 117
Shading treatment can be effectively performed in inside, such connection type so that the gap between fitting ring and reagent strip will not leak
Light can more efficiently carry out the sample light detection of noiseless light.
In the present embodiment, the reagent cartridge module 500 includes several reagent strips 101 and kit 102, the kit
102 is U-shaped, and 102 inner ring of the kit is equipped with reagent strip storage groove 103, and the reagent strip 101 is put in the reagent strip storage
Inside slot 103, the reagent strip 101 is elongated, and the left side of the reagent strip 101 is equipped with handle 104, the reagent strip 101
Middle part be equipped with circle detection hole 105, the right side in the circle detection hole 105 is equipped with reagent strip and captures square hole 106, the reagent
The lower section that item captures square hole 106 is equipped with four clamping shrapnels 107, and the clamping shrapnel 107, which is buckled in, takes reagent stick (not regarded in figure
Go out) on, the inner wall in 102 left side of the kit is equipped with two strip convex ribs 108, interior on the right side of the kit 102
Wall is equipped with three semicircle convex ribs 109, and the right side of the reagent strip crawl square hole 106 sets that there are six oblong reagent wells
110, the left side of the circle monitoring hole 105 is set there are one circular through hole 111, and the circular through hole 105 is internally provided with one
Circular reagent hole 113 there are two being set on the left of EUCUP112, the EUCUP112, the left side in the circular reagent hole 113 is equipped with
One short ellipse reagent wells 114, the left sides of the short oval reagent wells 114 set that there are two rectangular reagent wells 115, the circles
The outer edge of shape detection hole 105 is equipped with the round darkening ring 116 of a circle, the circle detection hole 105 and the round darkening ring
Card slot 117 is formed between 116, the card slot 117 is for installing fitting ring (not depending on going out in figure).
In the present embodiment, the both sides of the circular through hole 111, circle detection hole 105 and reagent strip crawl square hole 106 are equipped with
The centre of first reinforcing rib 118,110 bottom of oblong reagent wells is equipped with the second reinforcing rib 119, perpendicular to described second
Reinforcing rib 119 keeps flat muscle 120, the circular reagent hole 113, short oval reagent wells 114 and rectangular reagent wells 115 equipped with one
The centre of bottom is equipped with third reinforcing rib 121, perpendicular to the third reinforcing rib 121 be equipped with it is described keep flat muscle 120, described two
The 4th reinforcing rib 122 is equipped between first reinforcing rib 118, the upper surface of the reagent strip 101 is equipped with one layer of reagent diaphragm seal
(not depending on going out in figure).
In the present embodiment, the volley of rifle fire arm includes volley of rifle fire base assembly 601, volley of rifle fire motor 602, pipette tips component 603 and magnetic
Separation assembly 604, the volley of rifle fire motor 602 are set to the top of the volley of rifle fire base assembly 601, and the pipette tips component 603 connects
On the volley of rifle fire base assembly 1, the Magneto separate component 604 is located at the lower part of the volley of rifle fire base assembly 601, and is located at
The lower section of the pipette tips component 603, the volley of rifle fire base assembly 601 include volley of rifle fire substrate 605, volley of rifle fire motor fixing plate 606, rifle
Head guide rail 607 and pipette tips guide rail splice 608, the volley of rifle fire motor fixing plate 606 are set to the top of the volley of rifle fire substrate 605,
The pipette tips guide rail 607 is located on the volley of rifle fire substrate 605, and the pipette tips guide rail splice 608 is led mounted on the pipette tips
On rail 607, the volley of rifle fire motor 602 is mounted on the lower part of the volley of rifle fire motor fixing plate 606, the pipette tips guide rail 607
Right side is equipped with volley of rifle fire lead screw 609, and the volley of rifle fire lead screw 609 is connected to by belt 610 on the volley of rifle fire motor 602, described
Pipette tips component 603 is connected on the pipette tips guide rail splice 608, and the top of the pipette tips component 603 is equipped with Z-direction lead screw spiral shell
Mother 611, the Z-direction feed screw nut 611 is socketed on pipette tips lead screw 609 in the present embodiment, and the pipette tips component 603 includes rifle
Head clamping motor fixed plate 612, compresses lifting motor 614, volley of rifle fire fixed plate 615 and the volley of rifle fire 616, institute at pipette tips fixed substrate 613
It states pipette tips fixed substrate 613 to be connected on the pipette tips guide rail splice 68, the pipette tips clamping motor fixed plate 612 is set to
The top of the pipette tips fixed substrate 613, the compression lifting motor 614 are mounted on the pipette tips clamping motor fixed plate 612
On, the volley of rifle fire fixed plate 615 is connected on the pipette tips fixed substrate 613, and the volley of rifle fire 616 is connected to the volley of rifle fire
On fixed plate 615, the volley of rifle fire 616 is equipped with suction nozzle detection set 627, and the top of the volley of rifle fire 616 is transported equipped with pipette tips piston
Motion block 617 is equipped with piston and compresses guide rod 618 and piston compression spring between the volley of rifle fire 616 and the pipette tips piston motion block 617
619, two briquetting guide rods 620 and one are equipped between the pipette tips clamping motor fixed plate 612 and the pipette tips fixed substrate 613
Root piston clamping screw 621, the pipette tips piston motion block 617 are socketed in the briquetting guide rod 620 and piston clamping screw 621
On, the top of the piston clamping screw 621 is connected with the compression lifting motor 614, and is connected by belt 610, institute
The back side for stating volley of rifle fire board unit 601 is equipped with volley of rifle fire fixed plate 622 and volley of rifle fire guide rail splice 623, the Magneto separate component 604
On set there are four pipette tips slot 624, the pipette tips slot 624 is internally provided with magnetic head 625, and the rear portion of the Magneto separate component 604 is worn
It crosses the volley of rifle fire base assembly 601 and is equipped with Magneto separate component movement module 626.
Claims (12)
1. a kind of time-resolved fluorescence detector, it is characterised in that including rack, movement, sample rack component, inhale cephali disc assembly and
Kit components, the movement, are inhaled cephali disc assembly and kit components set on the machine frame inside and are fixed on sample rack component
The machine frame inside, the sample rack component inhale cephali disc assembly and kit components set on the outside of the movement, the movement
Module, volley of rifle fire arm and detection module are incubated including sample arm, two, the incubation module is set to the detection module and row side by side
The lower section of rifle arm, the top that the sample arm is set to the sample rack component, inhales cephali disc assembly and kit components, the incubation
The lower section of module is equipped with ash can, and shell is enclosed on the outside of the rack, and the shell is equipped with display, consumptive material adding mouth
And waste outlet, set that there are four stabilizer blades below the rack.
2. time-resolved fluorescence detector as described in claim 1, it is characterised in that the sample arm is transported including the first X axis
It dynamic component, the first Y-motion component, single rifle component and takes and beats component, the first Y-motion component is connected to described the
On one X-motion component, and moved on the first X-motion component, it is described list rifle component and take beat component
It is connected on the first Y-motion component, and is moved on the first Y-motion component, the list rifle
Component includes sample arm rack, the first transmission component, the first driven subassembly and single armed, first transmission component and described first
Driven subassembly is set on the sample arm rack, and the first biography is connected between the first transmission component and first driven subassembly
Band is moved, the first fixed block is installed on first transmission belt, the single armed is connected on first fixed block, the list
The lower part of arm be equipped with suction nozzle detection set, it is described take beat component include the sample arm rack, the second transmission component, second driven group
Part takes reagent bar assembly and beats reagent bar assembly, and the sample arm rack is connected on the first Y-motion component,
Second transmission component and second driven subassembly are connected on the sample arm rack, second transmission component with
It is described to take reagent bar assembly by taking reagent bar to be connected to institute by the second transmission band connection between second driven subassembly
It states on the second transmission belt, the second fixed block is equipped between second transmission belt and the top for taking reagent bar, it is described
Reagent bar assembly is taken to be set to the lower part for taking reagent bar, it is described that reagent bar assembly is taken to include reagent strip righting module and take examination
Agent stick, the lower part for taking reagent stick to be set to the reagent strip righting module, the reagent strip righting module include first
Fixed plate, righting board, two righting compressed springs, two righting compressed spring fixed blocks, two beat reagent strip head and two are beaten
Reagent strip head return spring, it is described to beat reagent strip head across the righting compressed spring fixed block and the first fixed plate and connect
On the righting board, the righting compressed spring passes through first fixed plate and consolidates set on the righting compressed spring
Determine between block and righting board, the reagent bar assembly of beating includes breaking reagent batten and beating reagent bar, described to beat reagent batten position
In the top for beating reagent strip head.
3. time-resolved fluorescence detector as claimed in claim 2, it is characterised in that the first X-motion component and
One Y-motion component includes fixed plate, guide rail and Power Component, and second fixed block is equipped with first baffle, described
The top of first baffle is equipped with the first photosensitive sensors, and the reagent batten of beating is equipped with second baffle, the second baffle
Top is equipped with the second photosensitive sensors, and the lower section for breaking reagent batten is equipped with reagent strip and captures identifier, described to beat reagent strip
The top of bar, which is connected with, beats reagent strip board motor.
4. time-resolved fluorescence detector as described in claim 1, it is characterised in that the incubation module includes incubating frame, temperature
Module, three reagent strip tablettings and third Power Component are educated, the incubation module is connected on the incubation frame, described three
Reagent strip tabletting is connected to the both sides for incubating frame, and the reagent strip tabletting is located at the top for incubating module, and described the
Three Power Components are mounted on the inside of the incubation frame, and the incubation module includes incubating box, reagent strip, suction nozzle and suction nozzle caching
Area, the reagent strip are deposited in inside the incubation box, and the suction nozzle is deposited in inside the suction nozzle buffer area, and the suction nozzle is slow
The outside for depositing area is equipped with waste material push plate, and the waste material push plate is located at the inside for incubating frame, described to incubate being internally provided with for box
Eight incubation blocks, the incubation block are internally provided with incubation slot, and the reagent strip is deposited in inside the incubation slot, the incubation box
Outside be enclosed with and incubate block heat-preservation cotton, the lower part for incubating box is equipped with heating plate pressing plate, under the heating plate pressing plate
Portion is equipped with lower incubation block heat-preservation cotton, and the suction nozzle buffer area is equipped with eight suction nozzle holes, and the suction nozzle hole is internally provided with compression spring, described
Compression spring top is equipped with compression spring gland, and the top of the compression spring gland is equipped with compression spring gland pressing plate, and the reagent strip tabletting is equipped with
Eight reagents go out sample preformed groove, and the incubation frame includes left socle, right support, connection transverse slat, connects riser and connecting rod, described
Transverse slat, connection riser and connecting rod is connected to be set between the left socle and right support.
5. time-resolved fluorescence detector as claimed in claim 4, it is characterised in that the bottom for incubating module is equipped with temperature
Educate box support, the left side for incubating box support is equipped with first leg, sets that there are two scroll wheel, institutes on the outside of the first leg
The middle part for stating right support is equipped with and rolls race, the scroll wheel in the rollings race roll inside, the incubation box support
Right side is equipped with the second supporting leg, and the inside of the left socle is equipped with transmission trough of belt, the incubation box support and the third power packages
Third transmission belt is connected between part, second supporting leg is connected on the third transmission belt, on the inside of described rolling race
Equipped with right mounting, the inside of the transmission trough of belt is equipped with left mounting, and the top of the left socle is equipped with long guideway, the incubation box
Holder is mounted on the long guideway and free movement, and the incubation box is mounted on the incubation box support.
6. time-resolved fluorescence detector as claimed in claim 2, it is characterised in that the detection module includes the second X axis
Moving component, the second Z-motion component and photodetector, the second Z-motion component are connected to second X-axis
It on moving component, and is moved on the second X-motion component, the photodetector is connected to the 2nd Z
It is axially moved on component, and is moved on the second Z-motion component, the second Z-motion component is equipped with
Rotary electric machine, the rotary electric machine are equipped with cam, and the photodetector is equipped with rotating wheel, and the cam rotation drives institute
Rotating wheel rotation is stated, the photodetector is driven to move up and down, the second Z-motion component and the photodetector
Between be equipped with Z tension springs, the photodetector includes xenon lamp, optical substrate, light path and photomultiplier, the photoelectricity
Multiplier tube is set to the top of the optical substrate, and the xenon lamp is set to the left side of the optical substrate, and the light path is set to
The inside of the optical substrate.
7. time-resolved fluorescence detector as claimed in claim 6, it is characterised in that set on the second X-motion component
There are cross slide way and the second Power Component, the second Z-motion component to be moved on the cross slide way, described second is dynamic
Power component drives the second Z-motion component to be moved on the cross slide way, is set on the second Z-motion component
There are vertical guide, the photodetector to be moved in the vertical guide, the light path includes the first lens group, 340
Optical filter, two are described to penetrating mirror, the second lens group, fitting ring, optical filter, 613/340 optical filter switch groups and the third lens group
First lens group and 340 optical filters are vertically set to inside the optical substrate, second lens group, fitting ring, optical filter,
613/340 optical filter switch groups and the third lens groups are laterally set to inside the optical substrate, and described two to penetrating, 45 ° of mirror is oblique to be set
Inside the optical substrate.
8. time-resolved fluorescence detector as claimed in claim 7, it is characterised in that first lens group, the second lens group
It is made of respectively two pieces of planoconvex lens with the third lens group, filter is equipped with positioned at the side of the photomultiplier on the optical substrate
The output end of mating plate switch motor, the optical filter switch motor is connected on the 613/340 optical filter switch groups, described
The side of xenon lamp is equipped with third photosensitive sensors, and the top of the optical filter switch motor is equipped with flying disc, and the flying disc rotation turns
The third photosensitive sensor is crossed, the lower part of the fitting ring is equipped with reagent strip, and the reagent strip is equipped with circle detection hole, institute
The outer edge for stating circle detection hole is equipped with the round darkening ring of a circle, shape between the circle detection hole and the round darkening ring
At card slot, the bottom of the fitting ring is equipped with retainer ring, and the retainer ring is embedded in inside the card slot.
9. time-resolved fluorescence detector as described in claim 1, it is characterised in that kit components include several reagent strips
And kit, the kit is U-shaped, and the kit inner ring is equipped with reagent strip storage groove, and the reagent strip is put in the examination
Inside agent storage groove, the reagent strip is elongated, and the left side of the reagent strip is equipped with handle, is set in the middle part of the reagent strip
There are circle detection hole, the right side in the circle detection hole to be equipped with reagent strip and capture square hole, the lower section of the reagent strip crawl square hole
Equipped with four clamping shrapnels, the clamping shrapnel, which is buckled in, to be taken on reagent stick, and the inner wall on the left of the kit is equipped with two
Strip convex ribs, the inner wall on the right side of the kit are equipped with three semicircle convex ribs, the right side of the reagent strip crawl square hole
Side is set there are six oblong reagent wells, is set on the left of the circle monitoring hole there are one circular through hole, in the circular through hole
Portion is set there are one EUCUP, is set on the left of the EUCUP there are two circular reagent hole, the left side in the circular reagent hole is equipped with one
A short oval reagent wells are set there are two rectangular reagent wells on the left of the short oval reagent wells, the circle detection hole
Outer edge is equipped with the round darkening ring of a circle, and card slot, the card are formed between the circle detection hole and the round darkening ring
Slot is for installing fitting ring.
10. time-resolved fluorescence detector as claimed in claim 9, it is characterised in that the circular through hole, circle detection hole
The both sides that square hole is captured with reagent strip are equipped with the first reinforcing rib, and the centre of oblong reagent wells bottom is equipped with second and reinforces
Muscle keeps flat muscle, the circular reagent hole, short oval reagent wells and rectangular reagent perpendicular to second reinforcing rib equipped with one
The centre of hole bottom is equipped with third reinforcing rib, keeps flat muscle equipped with described perpendicular to the third reinforcing rib, described two first add
The 4th reinforcing rib is equipped between strengthening tendons, the upper surface of the reagent strip is equipped with one layer of reagent diaphragm seal.
11. time-resolved fluorescence detector as described in claim 1, it is characterised in that the volley of rifle fire arm includes volley of rifle fire pedestal group
Part, volley of rifle fire motor, pipette tips component and Magneto separate component, the volley of rifle fire motor is set to the top of the volley of rifle fire base assembly, described
Pipette tips component is connected on the volley of rifle fire base assembly, and the Magneto separate component is located at the lower part of the volley of rifle fire base assembly,
And positioned at the lower section of the pipette tips component, the volley of rifle fire base assembly includes volley of rifle fire substrate, volley of rifle fire motor fixing plate, pipette tips guide rail
With pipette tips guide rail splice, the volley of rifle fire motor fixing plate is set to the top of the volley of rifle fire substrate, and the pipette tips guide rail is located at institute
It states on volley of rifle fire substrate, the pipette tips guide rail splice is mounted on the pipette tips guide rail, and the volley of rifle fire motor is mounted on institute
The lower part of volley of rifle fire motor fixing plate is stated, the right side of the pipette tips guide rail is equipped with volley of rifle fire lead screw, and the volley of rifle fire lead screw is connected by belt
It is connected on the volley of rifle fire motor, the pipette tips component is connected on the pipette tips guide rail splice, the pipette tips component
Top is equipped with Z-direction feed screw nut, and the Z-direction feed screw nut is socketed on pipette tips lead screw.
12. time-resolved fluorescence detector as claimed in claim 11, it is characterised in that the pipette tips component includes pipette tips pressure
Tight motor fixing plate, pipette tips fixed substrate compress lifting motor, volley of rifle fire fixed plate and the volley of rifle fire, the pipette tips fixed substrate connection
On the pipette tips guide rail splice, the pipette tips clamping motor fixed plate is set to the top of the pipette tips fixed substrate, institute
It states and compresses lifting motor on the pipette tips clamping motor fixed plate, it is solid that the volley of rifle fire fixed plate is connected to the pipette tips
Determine on substrate, the volley of rifle fire is connected on the volley of rifle fire fixed plate, and the volley of rifle fire is equipped with suction nozzle detection set, the volley of rifle fire
Top be equipped with pipette tips piston motion block, piston is equipped between the volley of rifle fire and the pipette tips piston motion block and compresses guide rod and work
Compression spring is filled in, two briquetting guide rods and a piston are equipped between the pipette tips clamping motor fixed plate and the pipette tips fixed substrate
Clamping screw, the pipette tips piston motion block are socketed on the briquetting guide rod and piston clamping screw, and the piston compresses
The top of lead screw is connected with the compression lifting motor, and is connected by belt, and the back side of the volley of rifle fire board unit is equipped with row
Rifle fixed plate and volley of rifle fire guide rail splice are set on the Magneto separate component there are four pipette tips slot, and the pipette tips slot is internally provided with
The rear portion of magnetic head, the Magneto separate component passes through the volley of rifle fire base assembly to be equipped with Magneto separate component movement module.
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| CN201810730443.4A CN108627491A (en) | 2018-07-05 | 2018-07-05 | A kind of time-resolved fluorescence detector |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN109307552A (en) * | 2018-11-29 | 2019-02-05 | 汇乐因斯福环保安全研究院（苏州）有限公司 | A kind of spark detection testing probe head performance device and method |
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| CN104450498A (en) * | 2014-12-16 | 2015-03-25 | 嘉兴凯实生物科技有限公司 | Nucleic acid extractor |
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