CN108627384A - Oscillation device, oscillation method and pretreating device for sample pre-treatments - Google Patents
Oscillation device, oscillation method and pretreating device for sample pre-treatments Download PDFInfo
- Publication number
- CN108627384A CN108627384A CN201810180761.8A CN201810180761A CN108627384A CN 108627384 A CN108627384 A CN 108627384A CN 201810180761 A CN201810180761 A CN 201810180761A CN 108627384 A CN108627384 A CN 108627384A
- Authority
- CN
- China
- Prior art keywords
- container
- mounting plate
- clamping limb
- clamping
- clamping piece
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/38—Diluting, dispersing or mixing samples
Landscapes
- Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
Abstract
The invention discloses a kind of oscillation devices for sample pre-treatments comprising：Holder shakes moving part and grabbing assembly；The holder has at least one column；The grabbing assembly is separately connected the holder and shakes moving part, and can be moved up and down along the holder, and crawl is located at the container for being individually loaded with sample and sample extraction object when moving up；The rolling moving part is for vibrating the container of crawl.High degree of automation of the present invention can realize batch samples " one-touch " processing, so that it may pre-treatment efficiency be greatly improved.
Description
Technical field
The present invention relates to sample detections more particularly to a kind of for the oscillation device of sample pre-treatments, oscillation method and preceding
Processing unit.
Background technology
In the noxious residual chemicals analytic processes such as existing fruits and vegetables pesticide, need to carry out pre-treatment to sample, for example crush,
Add extracts reagent, oscillation, extraction supernatant.But under the prior art, above-mentioned steps are mostly by being accomplished manually so that people
Power cost is high, and the if desired large batch of sample of single treatment, then can be multiplied the amount of labour；Although having occurred one
A little automatic equipments for being directed to the certain steps of pre-treatment, such as oscillator, extraction tube, can carry out certain steps in pre-treatment
Automatic business processing, but still lack the equipment for all automating all pre-treatment flows, it still cannot meet batch samples
The needs of pre-treatment.
Invention content
The present invention is directed to the drawbacks described above of the prior art, provides a kind of oscillation device for sample pre-treatments, oscillation side
Method and pretreating device, high degree of automation can realize batch samples " one-touch " processing, pre-treatment can be greatly improved
Efficiency.
The technical solution adopted by the present invention to solve the technical problems is：
On the one hand, a kind of oscillation device for sample pre-treatments is provided comprising：Holder, shaking
Part and grabbing assembly；
The holder has at least one column；The grabbing assembly is separately connected the holder and shakes moving part, and can be along institute
It states holder to move up and down, and crawl is located at the container for being individually loaded with sample and sample extraction object when moving up；The rolling
Moving part is for vibrating the container of crawl.
Preferably, the grabbing assembly includes：
Mobile base is set on the column, and is connect respectively with described one end for shaking moving part and Mobile base driving equipment,
And can the column described in the drive lower edge of the Mobile base driving equipment move up and down；
The first mounting plate, the second mounting plate and the third mounting plate set gradually from top to bottom；The first mounting plate connection
The rolling moving part；Second mounting plate is equipped with the first guide post worn for first mounting plate, and described first leads
The first spring is arranged on column；The third mounting plate is equipped with the second guide post worn for second mounting plate, and
It is arranged with second spring in second guide post；Second mounting plate is connect with first guiding column bottom；
At least one block piece is mounted on the column, for stopping moving down for the third mounting plate；
At least one third clamping piece is used to that the list being located on the container reception component to be clamped during moving up
A container；And each third clamping piece is rotatably connect with second mounting plate, the top of each third clamping piece with
The lower surface of first mounting plate abuts.
Preferably, the third clamping piece is forceps-like arrangement, including openable and closable first clamping limb and the second clamping limb；
Second mounting plate is equipped at least one clamping piece installation part, the first clamping limb of each third supporter and the
Two clamping limbs are rotatably connect with a clamping piece installation part, and the top of the first clamping limb and the second clamping limb is equal
It is abutted with the lower surface of first mounting plate.
Preferably, the oscillation device further includes control assembly, connects the Mobile base driving equipment and each institute
State third clamping piece, the first clamping limb of operating and each third clamping piece for controlling the Mobile base driving equipment and
The folding of second clamping limb.
Preferably, the oscillation device further includes：
Round turntable, and the round turntable is equipped at least one through-hole, each through-hole is for receiving a single container；
And turntable actuator, the round turntable is connected, for driving the round turntable to rotate so that described round turn
Container is delivered between the first clamping limb and the second clamping limb of opening by disk one by one.
Preferably, the rolling moving part is integrally formed with first mounting plate.
Preferably, the time vibrated every time is 30-60s.
On the other hand, a kind of sample pretreatment device is also provided comprising above-mentioned oscillation device.
On the other hand, a kind of sample oscillation method realized using above-mentioned oscillation device is also provided comprising following steps：
S1, the Mobile base driving equipment operating is controlled by the control assembly so that the Mobile base driving equipment is downward
It is mobile, it drives the Mobile base, shake moving part, the first mounting plate, the second mounting plate, third mounting plate, each third clamping piece entirety
It moves downward, until one end/both ends of the third mounting plate are stopped by the block piece, stops moving down；
S2, the Mobile base driving equipment drive the Mobile base persistently to move down so that first mounting plate is along first
Guide post moves downward, the second mounting plate is along the second guide post Continued downward motion, further such that first mounting plate
Lower surface squeezes the first clamping limb of each third clamping piece and the top of the second clamping limb, first clamping limb and second
Each autorotation of clamping limb is opened；
S3, the first clamping limb of the third clamping piece of container transport to left end and second are clamped by the round turntable
In region between arm；
S4, the Mobile base driving equipment operating is controlled by the control assembly so that the Mobile base driving equipment is upward
It is mobile, it drives the Mobile base, shake moving part, the first mounting plate, the second mounting plate, third mounting plate, each third clamping piece entirety
It moves upwards so that respectively gradually rotation is closed up for first clamping limb and the second clamping limb, thus clamps the container；
And S5, pass through the control assembly control shake moving part driving equipment operating so that the rolling moving part moves in a circle, into
And the container captured by the third clamping piece of left end is driven to be shaken, vibrated.
Preferably, further include following steps：
After S6, the container oscillation captured by the third clamping piece of left end, the movement is controlled by the control assembly
Seat moves down, and make each third clamping piece the first clamping limb and the second clamping limb each autorotation is opened again, will
The container being oscillated reapposes on the round turntable；
S7, the container being oscillated one station of advance, by the first folder of the third clamping piece of latter container transport to left end
In region between gripping arm and the second clamping limb, while the container being oscillated is corresponded to positioned at next third clamping piece
In region between first clamping limb and the second clamping limb, the control assembly controls the 4th driving equipment and transports again
Turn so that each third clamping piece clamps the container in the region between its first clamping limb and the second clamping limb；
And the control of S8, the control assembly is shaken moving part driving equipment and is operated again, is thus carried out again to clamped container
It shakes, oscillation, is repeated in, until all containers are vibrated.
The advantageous effect of technical solution of the present invention is：
" one-touch " automatic business processing that the present invention can be achieved sample delivery, vibrate, that is, only needing can be real by control assembly
The automated operation of existing above steps, is thus greatly improved the pre-treatment efficiency of batch samples.
Description of the drawings
Present invention will be further explained below with reference to the attached drawings and examples, in attached drawing：
Fig. 1 a are the vertical views of a sample pretreating device of the embodiment of the present invention；
Fig. 1 b are the overall structure figures of one container of the embodiment of the present invention；
Fig. 1 c are the side views of one container of the embodiment of the present invention；
Fig. 1 d are the schematic diagrames of one container stack of the embodiment of the present invention；
Fig. 2 a are the overall structure figures of one container grabbing assembly and sample container conveying assembly of the embodiment of the present invention；
Fig. 2 b are the side views of one container grabbing assembly and sample container conveying assembly of the embodiment of the present invention；
Fig. 2 c are the overall structure figures of one spiral transmission parts of the embodiment of the present invention；
Fig. 2 d are the overall structure figures of one container grabbing assembly of the embodiment of the present invention；
Fig. 3 is the overall structure figure of one container reception component of the embodiment of the present invention；
Fig. 4 a are the overall structure figures of one oscillation component of the embodiment of the present invention；
Fig. 4 b be the embodiment of the present invention one include grabbing assembly oscillation component overall structure figure；
Fig. 5 a are the overall structure figures of one oscillation component of the embodiment of the present invention；
Fig. 5 b are the front views of one oscillation component of the embodiment of the present invention；
Fig. 5 c are the side views of one oscillation component of the embodiment of the present invention；
Fig. 5 d are the overall structure figures of one third clamping piece of the embodiment of the present invention；
Fig. 6 is the schematic diagram of one third clamping piece holding vessels of the embodiment of the present invention；
Fig. 7 is the overall structure figure of one sampling assemble of the embodiment of the present invention；
Fig. 8 is the overall structure figure of one mounting bracket of the embodiment of the present invention；
Fig. 9 is the overall structure figure of one injecting assembly of the embodiment of the present invention；
Figure 10 is the overall structure figure of one needle tubing component of the embodiment of the present invention；
Figure 11 is the running schematic diagram of one needle tubing component of the embodiment of the present invention；
Figure 12 is the overall structure figure of one rinse bath of the embodiment of the present invention.
Specific implementation mode
In order to make the purpose of the present invention, technical solution and advantage be more clearly understood, below in conjunction with drawings and examples,
The present invention will be described in further detail.It should be understood that tool described herein
Body embodiment is only used for explaining the present invention, is not intended to limit the present invention.
Embodiment one：
Fig. 1 a show the sample pretreatment device of the present invention, can be used for fruits and vegetables and industrial crops pesticide is residual
Stay analysis comprising：
Sample container conveying assembly 100 is used to be loaded with the single container of sample or in short transverse
A pile container made of upper stacking（Such as the 2-4 container stacked gradually in the height direction）It is delivered to the first precalculated position
S1；In the present embodiment, the sample can be to have been subjected to the plant sample of segmentation or pulverization process, such as water fruits and vegetables, flowers
The equal industrial crops sample such as plant samples and rice, wheat, tealeaves（The homogeneous object generated including fragment or after crushed）；Institute
It is cup-shaped to state container, specifically, as depicted in figs. lb-lc, the container includes main part 20, prolongs along 20 outside wall surface of the main part
The first step portion 21 of stretching and along the second step portion 22 that 21 outside wall surface of first step portion is extended, and described second
Stage portion 22 is located at the top of the main part 20, and the main part 20 can be with the first step portion 21, second step portion 22
It is integrally formed, is thus convenient for manufacture and processing；Further；In the present embodiment, for purposes of illustration only, there are three the containers, point
It Wei not container P1, container P2 and container P3；Wherein, as shown in Figure 1 d, the of the second step portion 22 of container P1 and container P2
One stage portion 21 supports, so that the parts container P1 are set in the main part 20 of container P2；Similarly, the container P2 and
Container P3 is equally arranged stacking, thus stacks several containers in the height direction, and is followed successively by container P1, container P2 from top to bottom
And container P3, form a pile container；For ease of technical solution is described in detail, " a pile container " in the present embodiment includes only
Container P1, container P2 and the container P3 stacked gradually from top to bottom, but it is intended only as citing and uses, and does not constitute to the present invention
The restriction of protection domain.
Container grabbing assembly 200 is used to capture the single container positioned at the first precalculated position S1
Or a pile container, and it is detached with single container after single container is moved to the second precalculated position；
Container reception component 300, is used to receive the single container of separation, and container is delivered to third precalculated position one by one
S3；
Weigh assembly 800 is used to, to weighing positioned at the container of the third precalculated position S3, obtain weight data；
Automatic liquid-feeding component 700 connects the weigh assembly 800, for being added into corresponding container according to the weight data
Add the extracts reagent of corresponding amount（Phosphate extracting solution such as can be added according to the ratio of 5mL/g samples）；
Oscillation component 400 is used to capture at least one container, and is vibrated at least one container, and will be after oscillation
Container reappose on the container reception component 300；
Sampling assemble 500 is used to be delivered to the 4th successively by the container reception component 300 when the single container after oscillation
When the S4 of precalculated position, the sample extraction object in each container is accurately quantitatively extracted one by one（Such as 100 μ L supernatants of each sample extraction
Liquid etc.）, and it is transferred to collection vessel 600 in order（Such as 96 hole microwell plates）In, it is used for subsequent measurement；
And control assembly, it is used to control the sample container conveying assembly 100, container grabbing assembly 200, container reception group
The operating of part 300, oscillation component 400, sampling assemble 500, automatic liquid-feeding component 700 and weigh assembly 800；It needs to illustrate
It includes various types of processors, sensor and circuit structure in the control assembly to be, can be can be realized by corresponding program
To the sample container conveying assembly 100, container grabbing assembly 200, container reception component 300, oscillation component 400, sampling group
The control that part 500, automatic liquid-feeding component 700 and weigh assembly 800 specifically act, control process are the prior art,
This is repeated no more.
As shown in figs. 2 a-2 c, the sample container conveying equipment 100 includes：First driving equipment 1（Such as
Motor etc.）And the spiral transmission parts 2 of spring-like；
Wherein, the spiral transmission parts 2 are used to support the container, specifically, the spiral transmission parts 2 can pass through metal
Or spring-like structures made of plastics, it is formed with several receiving portions 211, each described accommodation section in the space for forming screw pitch
A container or a pile container can be accommodated in 211 so that container is supported, further, in the control assembly
Under control, first driving equipment 1 drives the spiral transmission parts 2 around own axis, thus by the single container
Or one pile container be delivered to the first precalculated position S1 one by one.
Such as Fig. 2 a-2b, shown in 2d, the container grabbing assembly 200 includes：Mounting base 3；And it is mounted on the mounting base
The first clamping member 4, the second clamping piece 4 ' on 3, the first folding actuator for driving the first clamping member 4 to open and close（Not
It shows）, the second folding actuator for driving second clamping piece 4 ' folding（It is not shown）And for driving described
The second driving equipment 5 that two clamping pieces 4 ' move up and down（Such as motor）；
The first clamping member 4 and the second clamping piece 4 ' are setting up and down in the height direction, and structure is identical, are tong-like knot
Structure includes 41 and second clamping part 42 of openable and closable first clamping part；And the first folding actuator, the second folding drive
Moving part and the second driving equipment 5 are connect with the control assembly, and its operation is controlled by the control assembly；
Specifically, before the single container or a pile container are conveyed, control assembly control the first folding driving
Part, second folding actuator running so that the first clamping member 4, the second clamping piece 4 ' the first clamping part 41 and second
Clamping part 42 is in opening state, at this point, the first precalculated position S1 is clamped for first clamping part 41 and second
Region between portion 42；
One pile container be transported in the first precalculated position S1 after, the first clamping member 4, the second clamping piece 4 ' first
Clamping part 41 and the second clamping part 42 close up so that the lower surface in the second step portion 22 of the container P3 of bottom with it is described
The upper surface of second clamping piece 4 ' supports, and makes inverse（" inverse " herein refers to calculating from the bottom up）Second appearance
The lower surface in the second step portion 22 of device P2 is located at the top of the upper surface of the first clamping member 4, thus by the appearance of bottom
The second step portion 22 of device P3 is shelved on underlying second clamping piece 4 ', and the weight of entire pile container is supported with this
Amount；
Further, second clamping piece 4 ' moves down under the driving of second driving equipment 5 so that bottom
Container P3 and upper container P2, container P1 are detached from, meanwhile, under the effect of gravity, second of the penultimate container P2
The lower surface in rank portion 22 and the upper surface of the first clamping member 4 support, and are supported from there through the first clamping member 4 remaining
The weight of container P2 and container P1；
Further, second clamping piece 4 ' is opened after being moved downward to the second reservation position S2, thus bottom
Container P3 is fallen, and realizes the separation with the container grabbing assembly 200 and other containers；
Further, second clamping piece 4 ', which is kept open, moves up, and closes up when returning to initial position, meanwhile,
The first clamping member 4 is opened so that penultimate container P2 falls, and under the effect of gravity so that penultimate container
The lower surface in the second step portion 22 of P2 and the upper surface of second clamping piece 4 ' support, meanwhile, the first clamping member 4 is again
It is secondary to close up so that the lower surface in the second step portion 22 of third last container P1 is located at the upper surface of the first clamping member 4
Top, at this time container P2 be located at bottom, the disengaging process of said vesse P3 is repeated, until all containers are with single container
Form detached one by one.
As shown in figure 3, the container reception component 300 includes：
Round turntable 6, and the round turntable 6 is equipped at least one through-hole 61, each through-hole 61 is for receiving one
The single container detached with the second clamping piece 4 ' of the container grabbing assembly 200 such as container P1, P2, P3, and passes through through-hole 61
The position of fixed described single container P1, P2, P3；
And third driving equipment 7（Such as motor）, it is connect respectively with the control assembly and round turntable 6, passes through institute
The operating that control assembly controls the third driving equipment 7 is stated, the round turntable 6 is thus driven to be rotated according to desired speed,
So that each single container with second clamping piece 4 ' separation can accurately be fallen in a corresponding through-hole 61, into one
Step, single container is being received, during container P1, P2, P3, the round turntable 6 persistently rotates, thus constantly
Reception container, and container is delivered to the third precalculated position S3 one by one.
Such as Fig. 4 a-4b, shown in Fig. 5 a-5b, the oscillation component 400 includes：Holder 8 shakes moving part 14 and grabbing assembly；
The grabbing assembly is separately connected the holder 8 and shakes moving part 14, and can be moved up and down along the holder 8, and to moving up
Crawl is located at the single container on the round turntable 6 when dynamic；The rolling moving part 14 is then used to vibrate the container of crawl；
Specifically, the holder 8 includes at least one column 81, the grabbing assembly includes：
Mobile base 82 is set on the column 81, and respectively with it is described shake moving part 14 one end and the 4th driving equipment
83（That is Mobile base driving equipment, such as motor）Connection, the 4th driving equipment 83 are connect with the control assembly, and in institute
It states and is operated under the control of control assembly, and then the Mobile base 82 is driven to be moved up and down along the column 81；
The first mounting plate 10, the second mounting plate 15 and the third mounting plate 16 set gradually from top to bottom；Second installation
Plate 15 is equipped with the first guide post 101 worn for first mounting plate 10, and the is arranged in first guide post 101
One spring 102, meanwhile, the third mounting plate 16 is equipped with the second guide post 103 worn for second mounting plate 15, and
It is arranged with second spring 104 in second guide post 103；Second mounting plate 15 and 101 bottom of the first guide post
Connection, and the first spring 102 is different from the elasticity of second spring 104；
The other end for shaking moving part 14 connects first mounting plate 10；Preferably, the rolling moving part 14 is pacified with described first
Loading board 10 is integrally formed；
At least one block piece 84 is mounted on the column 81, for stopping moving down for the third mounting plate 16；
At least one third clamping piece 9, as shown in Fig. 5 c-5d, the third clamping piece 9 is forceps-like arrangement, including openable and closable
First clamping limb 91 and the second clamping limb 92；Second mounting plate 15 is equipped at least one clamping piece installation part 17, often
The first clamping limb 91 and the second clamping limb 92 of the one third supporter 9 are rotatable with a clamping piece installation part 17
Connection, and the top A of the first clamping limb 91 and the second clamping limb 92 is abutted with the lower surface of first mounting plate 10；
And the 5th driving equipment 83a（Such as motor）, the rolling moving part 14 is connected, for the control in the control assembly
It is lower that the rolling moving part 14 is driven to move in a circle, and then to first mounting plate 10, the second mounting plate 15, third mounting plate
16, it third clamping piece 9 and is shaken by the container that the third clamping piece 9 captures, thus to the sample in the container
And extraction of substance is vibrated.
As shown in fig. 6,9 holding vessels of third clamping piece and the method vibrated to the container are as follows（With 3
For a third clamping piece 9）：
Before 9 holding vessels of third clamping piece, the 4th driving equipment 83 drives Mobile base 82, shakes the peace of moving part 14, first
Loading board 10, the second mounting plate 15, third mounting plate 16, each third clamping piece 9 are whole to be moved downward, until the third mounting plate
16 one end/both ends are stopped by the block piece 84, stop moving down, but the first mounting plate 10, the second mounting plate 15 are still distinguished
It being moved downward along the first guide post 101 and the second guide post 103, the first spring 102 is compressed with second spring 104, meanwhile,
The lower surface of first mounting plate 10 squeezes the first clamping limb 91 of each third clamping piece 9 and the top of the second clamping limb 92
A so that each autorotation of first clamping limb, 91 and second clamping limb 92 is opened；
Further, round turntable 6 rotates a station so that container P3 is located at the first folder of the third clamping piece 9 of left end
In region between gripping arm 91 and the second clamping limb 92, at this point, the 4th driving equipment 83 drive Mobile base 82, shake moving part 14,
First mounting plate 10, the second mounting plate 15, third mounting plate 16, each third clamping piece 9 are whole to be moved upwards, then the third peace
Loading board 16 is gradually distance from the block piece 84, the first mounting plate 10, the second mounting plate 15 respectively along the first guide post 101 and
Second guide post 103 moves upwards, and the first spring 102 gradually restores to the original state with second spring 104, meanwhile, first installation
The lower surface of plate 10 releases the extruding on the top of first clamping limb, 91 and second clamping limb 92 so that first folder
Respectively gradually rotation is closed up for gripping arm 91 and the second clamping limb 92, and the first clamping limb of the third clamping piece 9 of left end simultaneously
91 and second clamping limb 92 during moving up, be gradually moved to the following table in the second step portion 22 of the container P3
The lower section in face, and the lower surface with the second step portion 22 of the container P3 during continuing to move up supports, thus
Securely clamp the second step portion 22 of the container P3；
Further, the 5th driving equipment 83a drives the rolling moving part 14 to do circumference under the control of the control assembly
Movement, and then drive and shaken, vibrate by the container P3 that the third clamping piece 9 of left end captures；
Further, after being vibrated to container P3, the Mobile base 82 is controlled by the control assembly and is moved down, and
So that each autorotation is opened again for the first clamping limb 91 and the second clamping limb 92 of each third clamping piece 9（Opening process with most
The opening process of the third clamping piece 9 of left end is identical, and details are not described herein）, the container P3 being oscillated is reapposed into institute
It states on round turntable 6；Then round turntable 6 rotates a station again so that is located at the latter container of previous vessels downstream, i.e.,
The container P2 in the downstreams the container P3 is located at the first clamping limb 91 and the second clamping limb 92 of the third clamping piece 9 of left end
Between region in, and the container P3 being oscillated simultaneously is located at the first clamping limb 91 and second of next third clamping piece 9
In region between clamping limb 92, at this point, the 4th driving equipment 83 operates again so that the third clamping piece 9 of left end is clamped
The second step portion 22 of container P2, meanwhile, previous container, i.e. the second step portion of container P3 is clamped in intermediate third clamping piece 9
22（Clamping process is identical as the second step portion 22 of 9 holding vessels P3 of the third clamping piece of left end, and details are not described herein）；
Further, the 5th driving equipment 83a drives the rolling moving part 14 to move in a circle under the control of the control assembly,
The latter container P2 being crawled and previous container P3 is driven to synchronize shaking, oscillation in turn；
Further, after to container P2 and container P3 oscillations, the first clamping limb 91 and second of each third clamping piece 9
Clamping limb 92 again open by each autorotation（Opening process is identical as the opening process of third clamping piece 9 of left end, herein no longer
It repeats）, then round turntable 6 rotate a station again so that be located at the downstreams the container P2 container P1 be located at left end
Third clamping piece 9 the first clamping limb 91 and the second clamping limb 92 between region in, and the container being oscillated simultaneously
The corresponding area between the first clamping limb 91 and the second clamping limb 92 of a third clamping piece 9 in respective downstream P2, P3
In domain, at this point, the 4th driving equipment 83 operates again so that the second step of the 9 holding vessels P1 of third clamping piece of left end
9 holding vessels of third clamping piece in portion 22, the second step portion 22 of intermediate 9 holding vessels P2 of third clamping piece and right end
The second step portion 22 of P3（Clamping process is identical as the second step portion 22 of 9 holding vessels P3 of the third clamping piece of left end,
Details are not described herein）；Further, the 5th driving equipment 83a drives the shaking under the control of the control assembly
Part 14 moves in a circle, and then the container P1, container P2 and the container P3 that are crawled is driven to synchronize shaking, oscillation.This implementation
In example, the time vibrated every time is 30-60s（Preferably 45s）.
As shown in fig. 7, the sampling assemble 500 includes：Injecting assembly 11, be used for when after oscillation container P1, P2,
When P3 is delivered to the 4th precalculated position S4 one by one by the container reception component, the sample extraction in single container is extracted one by one
Object；And mounting bracket 12, it is used to install the injecting assembly 11.
Specifically, as Figure 7-8, the mounting bracket 12 includes：Fixed link 121 and vertical with the fixed link 121
The mobile bar 122 that is arranged and can be slided along the fixed link 121；Specifically, the fixed link 121 has 2, and it is relatively parallel
Setting, 121 both ends of the fixed link are respectively arranged with first and wear portion 1211 and second wear portion 1211 ', and described first wears
If portion 1211 is threaded through in a fixed link 121, described second, which wears portion 1211 ', is threaded through in another fixed link 121, and first
It wears portion 1211 and second wears portion 1211 ' respectively along 121 synchronous slide of corresponding fixed link, and then drive the mobile bar
122 move along Y-direction（That is the dotted arrow direction in Fig. 7）；Preferably, the movement of the mobile bar 122 can by with control group
6th driving equipment of part connection（Such as belt drive）It completes；
The injecting assembly 11 is mounted in the mobile bar 122, and can be moved along the mobile bar 122 and X occurs to moving（I.e.
Solid arrow direction in Fig. 7）, the sample extraction object in the single container of the extraction is thus injected into the 5th precalculated position
（It is such as moved at the collection vessel 600 in Fig. 1）；
Specifically, as shown in figure 9, the injecting assembly 11 includes：Mounting base 111；Part 112 is worn, the installation is connected to
On seat 111, for being threaded through the mobile bar 122, and it can be moved along the mobile bar 122；Guide rail 120 is connected to institute
It states and wears 112 bottom of part, and pass through the mounting base 111；And needle tubing component, it is connected in the mounting base 111, is used for
It is extend into pipette samples extract in the container, and the sample extraction object is injected into the 5th precalculated position；
Preferably, the mounting base 111 and the 7th driving equipment controlled by the control assembly（Such as belt drive）Even
It connects, and the guide rail 120 described in the driving lower edge of the 7th driving equipment moves up and down.
Further, such as Fig. 9, shown in 11, the needle tubing component includes：Syringe needle 113, hose, the 8th driving equipment 114,
Cylinder 115, push rod 116, plug 117 and the push plate 118 of inner hollow；
Wherein, the syringe needle 113 is connected in the mounting base 111, and can be moved with the mounting base 111；The push rod 116
One end connects the plug 117, push plate 118 described in the other end, and the plug 117 is set to inside the cylinder 115, and with
The inner wall shape of the cylinder 115 matches；The push plate 118 and the 8th driving equipment 114（It can be motor etc.）Connection,
And moved up and down under the driving of the 8th driving equipment 114, and then drive plug 117 described by the push rod 116
It is moved up and down inside cylinder 115；115 end of the cylinder is additionally provided with the connector 119 being connected to 115 inside of the cylinder, described
Hose one end is connected to the connector 119, and the other end is connected to the syringe needle 113；
When the plug 117 moves down in the cylinder 115（That is the solid arrow direction in Figure 10）When, in cylinder 115
Subnormal ambient is formed, the sample extraction object in the container passes sequentially through syringe needle 113, hose is drawn into the cylinder 115
It is stored；When the plug 117 moves up in the cylinder 115（That is the dotted arrow direction in Figure 10）When, by needle
The sample extraction object stored in cylinder 115 is injected into precalculated position by hose, syringe needle 113（The collection vessel being such as injected into Fig. 1
In 600）.
In addition, to improve the intelligence degree of whole equipment, the 6th driving equipment, the 7th driving equipment and the 8th
Driving equipment 114 can connect the control assembly, and be operated under the control of control assembly, and then drive mobile bar 122, peace
Fill seat 111 and the linear motion of push plate 118；Meanwhile to avoid the cross contamination, sample pretreatment device of the invention from further including
Rinse bath 123 is used to accommodate cleaning materials（Such as cleaning solution）, and by the cleaning materials before each pipette samples extract
The syringe needle 113 is cleaned.For example, the sample extraction object stored in the syringe 115 is injected into precalculated position（Such as note
It is mapped in the collection vessel 600 in Fig. 1）Afterwards, the control assembly controls the movement of the 6th driving equipment, thus drives mobile bar
122 along X/Y to moving to above the rinse bath 123, further, the control assembly controls the movement of the 7th driving equipment,
So that syringe needle 113 and mounting base 111 move down, until the syringe needle 113 immerses in the cleaning materials of rinse bath 123, and it is cleaned,
After cleaning, the control assembly again transport by the 6th driving equipment of secondary control, the 7th driving equipment and the 8th driving equipment 114
It is dynamic, and then the linear motion of mobile bar 122, mounting base 111 and push plate 118 is driven again, it carries out sample in subsequent vessel and carries
The absorption of object and the cleaning of syringe needle 113 are taken, is repeated in.
Further, such as Fig. 7, shown in 9, the sample pretreatment device further includes：Component 900 is recycled, is used to recycle
Sample has been extracted the container of sample extraction object, and is transported to recovery position（Such as waste recovery container）；Wherein, described
Recycling component 900 includes：4th clamping piece 13 is connected in the mounting base 111, and can be with the injecting assembly 11
Mobile, similar, the 4th clamping piece 13 is similarly connect with the control assembly, can be forceps-like arrangement, and folding is dynamic
Work is controlled by the control assembly, and is clamped or puts down container by opening and closing movement；
Specifically, the sample extraction object in single container is injected the extraction of component 11, and after being injected into the 5th precalculated position,
The control assembly controls the round turntable 6 and turns round a station；Further, the control assembly controls the described 6th again
Driving equipment, the operating of the 7th driving equipment, to drive mobile bar 122 and mounting base 111 to move along a straight line so that the described 4th
Clamping piece 13 moves to the position being extracted where the container of sample extraction object, and further, the 4th clamping piece 13 exists
Close up under the control of the control assembly, thus capture the container for being extracted sample extraction object, the control assembly is again at this time
6th driving equipment described in secondary control, the operating of the 7th driving equipment, mobile bar 122 and mounting base 111 move along a straight line again, institute
It states the 4th clamping piece 13 to be moved to recovery position and open, container enters recovery position, and is recovered further.
Embodiment two：
The present embodiment additionally provides a kind of method that above-mentioned sample pretreatment device carries out sample pre-treatments comprising following step
Suddenly：
S1, it is sequentially placed several containers for being loaded with sample on the sample container conveying assembly, and is held by the sample
Single container or one are piled up container transport to the first precalculated position by device conveying assembly；
S2, the crawl of container grabbing assembly pile up container positioned at the single container in first precalculated position or a pile container from one
Middle sub-department's single container, and detached with single container after being moved to the second precalculated position；
S3, container reception component receive the single container of separation, and by least one container transport to third precalculated position；
S4, oscillation component capture at least one container, and are vibrated at least one container, and by the receptacle after oscillation
In new placement to the container reception component, and the 4th precalculated position is delivered to by the container reception component；
And S5, before sampling, the syringe needle of injecting assembly is cleaned, then by sampling assemble one by one accurate quantification extract it is single
Sample extraction object in a container, and be injected into the collection vessel in precalculated position, it is used for subsequent analysis.
It should be noted that the technical characteristic in above-described embodiment one, two can carry out arbitrary combination, the technology being composed
Scheme all belongs to the scope of protection of the present invention.
In conclusion invention can realize sample delivery, weigh, add extract, oscillation, sample extraction object carry
Take, container recycling and etc. " one-touch " automatic business processing, that is, in use, only needing to set in control assembly in advance
Corresponding motion flow, timing node trigger the automated operation that above steps can be realized after pre-treatment program, thus pole
The big pre-treatment efficiency for improving batch samples.
The foregoing is merely presently preferred embodiments of the present invention, is not intended to limit the invention, it is all the present invention spirit and
Within principle, any modification, equivalent replacement, improvement and so on should all be included in the protection scope of the present invention.
Claims (10)
1. a kind of oscillation device for sample pre-treatments, which is characterized in that including：Holder, shake moving part,
And grabbing assembly；
The holder has at least one column；The grabbing assembly is separately connected the holder and shakes moving part, and can be along institute
It states holder to move up and down, and crawl is located at the container for being individually loaded with sample and sample extraction object when moving up；The rolling
Moving part is for vibrating the container of crawl.
2. oscillation device according to claim 1, which is characterized in that the grabbing assembly includes：
Mobile base is set on the column, and is connect respectively with described one end for shaking moving part and Mobile base driving equipment,
And can the column described in the drive lower edge of the Mobile base driving equipment move up and down；
The first mounting plate, the second mounting plate and the third mounting plate set gradually from top to bottom；The first mounting plate connection
The rolling moving part；Second mounting plate is equipped with the first guide post worn for first mounting plate, and described first leads
The first spring is arranged on column；The third mounting plate is equipped with the second guide post worn for second mounting plate, and
It is arranged with second spring in second guide post；Second mounting plate is connect with first guiding column bottom；
At least one block piece is mounted on the column, for stopping moving down for the third mounting plate；
At least one third clamping piece is used to that the list being located on the container reception component to be clamped during moving up
A container；And each third clamping piece is rotatably connect with second mounting plate, the top of each third clamping piece with
The lower surface of first mounting plate abuts.
3. oscillation device according to claim 2, which is characterized in that the third clamping piece is forceps-like arrangement, including can
The first clamping limb and the second clamping limb of folding；Second mounting plate is equipped at least one clamping piece installation part, each
The first clamping limb and the second clamping limb of the third supporter are rotatably connect with a clamping piece installation part, and
The top of first clamping limb and the second clamping limb is abutted with the lower surface of first mounting plate.
4. oscillation device according to claim 3, which is characterized in that the oscillation device further includes control assembly, is connected
Connect the Mobile base driving equipment and each third clamping piece, for control the operating of the Mobile base driving equipment with
And the folding of the first clamping limb and the second clamping limb of each third clamping piece.
5. oscillation device according to claim 4, which is characterized in that the oscillation device further includes：
Round turntable, and the round turntable is equipped at least one through-hole, each through-hole is for receiving a single container；
And turntable actuator, the round turntable is connected, for driving the round turntable to rotate so that described round turn
Container is delivered between the first clamping limb and the second clamping limb corresponding and open by disk one by one.
6. according to claim 1-5 any one of them oscillation devices, which is characterized in that the rolling moving part is installed with described first
Plate is integrally formed.
7. oscillation device according to claim 6, which is characterized in that the time vibrated every time is 30-60s.
8. a kind of sample pretreatment device, which is characterized in that including oscillation device as claimed in claim 7.
9. the sample oscillation method that a kind of oscillation device using in claim 5 is realized, which is characterized in that including walking as follows
Suddenly：
S1, the Mobile base driving equipment operating is controlled by the control assembly so that the Mobile base driving equipment is downward
It is mobile, it drives the Mobile base, shake moving part, the first mounting plate, the second mounting plate, third mounting plate, each third clamping piece entirety
It moves downward, until one end/both ends of the third mounting plate are stopped by the block piece, stops moving down；
S2, the Mobile base driving equipment drive the Mobile base persistently to move down so that first mounting plate is along first
Guide post moves downward, the second mounting plate is along the second guide post Continued downward motion, further such that first mounting plate
Lower surface squeezes the first clamping limb of each third clamping piece and the top of the second clamping limb, first clamping limb and second
Each autorotation of clamping limb is opened；
S3, the first clamping limb of the third clamping piece of container transport to left end and second are clamped by the round turntable
In region between arm；
S4, the Mobile base driving equipment operating is controlled by the control assembly so that the Mobile base driving equipment is upward
It is mobile, it drives the Mobile base, shake moving part, the first mounting plate, the second mounting plate, third mounting plate, each third clamping piece entirety
It moves upwards so that respectively gradually rotation is closed up for first clamping limb and the second clamping limb, thus clamps the container；
And S5, pass through the control assembly control shake moving part driving equipment operating so that the rolling moving part moves in a circle, into
And the container captured by the third clamping piece of left end is driven to be shaken, vibrated.
10. sample oscillation method as claimed in claim 9, which is characterized in that further include following steps：
After S6, the container oscillation captured by the third clamping piece of left end, the movement is controlled by the control assembly
Seat moves down, and make each third clamping piece the first clamping limb and the second clamping limb each autorotation is opened again, will
The container being oscillated reapposes on the round turntable；
S7, the container being oscillated one station of advance, by the first folder of the third clamping piece of latter container transport to left end
In region between gripping arm and the second clamping limb, while the container being oscillated is corresponded to positioned at next third clamping piece
In region between first clamping limb and the second clamping limb, the control assembly controls the 4th driving equipment and transports again
Turn so that each third clamping piece clamps the container in the region between its first clamping limb and the second clamping limb；
And the control of S8, the control assembly is shaken moving part driving equipment and is operated again, is thus carried out again to clamped container
It shakes, oscillation, is repeated in, until all containers are vibrated.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810180761.8A CN108627384B (en) | 2018-03-05 | 2018-03-05 | Oscillation device, oscillation method and pretreatment device for sample pretreatment |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810180761.8A CN108627384B (en) | 2018-03-05 | 2018-03-05 | Oscillation device, oscillation method and pretreatment device for sample pretreatment |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN108627384A true CN108627384A (en) | 2018-10-09 |
| CN108627384B CN108627384B (en) | 2020-08-04 |
Family
ID=63706078
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201810180761.8A Active CN108627384B (en) | 2018-03-05 | 2018-03-05 | Oscillation device, oscillation method and pretreatment device for sample pretreatment |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN108627384B (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111948359A (en) * | 2020-08-13 | 2020-11-17 | 郑州大学 | Safe rapid detection equipment for chronic disease food therapy |
Citations (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN201886028U (en) * | 2010-10-27 | 2011-06-29 | 山东博科生物产业有限公司 | Test sample carrier clamper for assay |
| CN203611256U (en) * | 2013-12-24 | 2014-05-28 | 衢州中科数字化工程技术有限公司 | Mechanical gripper for industrial robot |
| CN104568564A (en) * | 2015-02-13 | 2015-04-29 | 重庆天海医疗设备有限公司 | Intelligent stirring and uniformly mixing device for blood collection tubes |
| CN105572407A (en) * | 2016-01-27 | 2016-05-11 | 广州万孚生物技术股份有限公司 | Full-automatic fluorescent quantitative immunity analyzer and detection method |
| CN105835082A (en) * | 2016-05-03 | 2016-08-10 | 郭强 | Electromagnetic mechanical gripper device |
| CN205580846U (en) * | 2016-03-04 | 2016-09-14 | 深圳普门科技有限公司 | Test tube body fluid shakes even device |
| CN106078786A (en) * | 2016-08-12 | 2016-11-09 | 镇江成泰自动化技术有限公司 | A kind of electrokinetic cell height suitability not damaged automatic clamping grip device |
| CN205928698U (en) * | 2016-08-12 | 2017-02-08 | 镇江成泰自动化技术有限公司 | Fixture device is pressed from both sides to automatic embracing of high suitability not damaged of power battery |
| CN106645765A (en) * | 2017-01-06 | 2017-05-10 | 刘丹 | Automatic analysis device and sample analysis method |
| CN106826888A (en) * | 2017-03-07 | 2017-06-13 | 北京林业大学 | A kind of coordinated type elastic mechanical paw |
| CN107160420A (en) * | 2017-07-08 | 2017-09-15 | 佛山市正略信息科技有限公司 | A kind of mechanical paw with stopping means |
| CN206515349U (en) * | 2016-12-16 | 2017-09-22 | 深圳雷杜生命科学股份有限公司 | It is a kind of that there is the gripper equipment for mixing function |
| CN206937356U (en) * | 2017-07-06 | 2018-01-30 | 重庆瀚海塑胶制品有限公司 | A kind of good catching robot of steadiness |
| CN208224288U (en) * | 2018-05-03 | 2018-12-11 | 安图实验仪器(郑州)有限公司 | Grabbing device with auto-reset function |
-
2018
- 2018-03-05 CN CN201810180761.8A patent/CN108627384B/en active Active
Patent Citations (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN201886028U (en) * | 2010-10-27 | 2011-06-29 | 山东博科生物产业有限公司 | Test sample carrier clamper for assay |
| CN203611256U (en) * | 2013-12-24 | 2014-05-28 | 衢州中科数字化工程技术有限公司 | Mechanical gripper for industrial robot |
| CN104568564A (en) * | 2015-02-13 | 2015-04-29 | 重庆天海医疗设备有限公司 | Intelligent stirring and uniformly mixing device for blood collection tubes |
| CN105572407A (en) * | 2016-01-27 | 2016-05-11 | 广州万孚生物技术股份有限公司 | Full-automatic fluorescent quantitative immunity analyzer and detection method |
| CN205580846U (en) * | 2016-03-04 | 2016-09-14 | 深圳普门科技有限公司 | Test tube body fluid shakes even device |
| CN105835082A (en) * | 2016-05-03 | 2016-08-10 | 郭强 | Electromagnetic mechanical gripper device |
| CN106078786A (en) * | 2016-08-12 | 2016-11-09 | 镇江成泰自动化技术有限公司 | A kind of electrokinetic cell height suitability not damaged automatic clamping grip device |
| CN205928698U (en) * | 2016-08-12 | 2017-02-08 | 镇江成泰自动化技术有限公司 | Fixture device is pressed from both sides to automatic embracing of high suitability not damaged of power battery |
| CN206515349U (en) * | 2016-12-16 | 2017-09-22 | 深圳雷杜生命科学股份有限公司 | It is a kind of that there is the gripper equipment for mixing function |
| CN106645765A (en) * | 2017-01-06 | 2017-05-10 | 刘丹 | Automatic analysis device and sample analysis method |
| CN106826888A (en) * | 2017-03-07 | 2017-06-13 | 北京林业大学 | A kind of coordinated type elastic mechanical paw |
| CN206937356U (en) * | 2017-07-06 | 2018-01-30 | 重庆瀚海塑胶制品有限公司 | A kind of good catching robot of steadiness |
| CN107160420A (en) * | 2017-07-08 | 2017-09-15 | 佛山市正略信息科技有限公司 | A kind of mechanical paw with stopping means |
| CN208224288U (en) * | 2018-05-03 | 2018-12-11 | 安图实验仪器(郑州)有限公司 | Grabbing device with auto-reset function |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111948359A (en) * | 2020-08-13 | 2020-11-17 | 郑州大学 | Safe rapid detection equipment for chronic disease food therapy |
| CN111948359B (en) * | 2020-08-13 | 2022-09-16 | 郑州大学 | Safety rapid detection equipment for chronic disease food therapy |
Also Published As
| Publication number | Publication date |
|---|---|
| CN108627384B (en) | 2020-08-04 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN108627661A (en) | Sample pretreatment device and sample-pretreating method | |
| CN109249402B (en) | Robot, method and device for automatically recycling garbage by robot and storage medium | |
| CN208076547U (en) | Sample pretreatment device | |
| CN112024424B (en) | Man-machine cooperation type garbage sorting system | |
| CN102581605A (en) | Multi-workstation nut clamping and conveying device | |
| CN105668251B (en) | A kind of sample dish access device and sample dish access method | |
| JP2011116507A (en) | Refuse sorting device | |
| CN107350800B (en) | A kind of clothes hanger automatic assembling mechanism | |
| CN108627384A (en) | Oscillation device, oscillation method and pretreating device for sample pre-treatments | |
| CN109178515A (en) | Needle mechanism for automatic unpacking unloader structure | |
| CN109877577A (en) | A kind of assemble method and automatical and efficient kludge of novel safety pin | |
| CN113925025A (en) | Full-automatic insect breeding line | |
| CN206634662U (en) | A kind of Y types swing arm Sorting ＆ Picking System | |
| CN206095977U (en) | Early pregnant test paper's processing equipment | |
| CN108627660A (en) | Container dispenser, allocator and pretreating device for sample pre-treatments | |
| CN109482510A (en) | A kind of full-automatic hardness detection sorter | |
| CN208199738U (en) | Sort overturning system | |
| CN205720272U (en) | Sample clearing apparatus abandoned by a kind of sample dish and sample is taken inventory and taken cabinet | |
| CN208853725U (en) | Automatic lathe and its material-receiving device | |
| CN207482683U (en) | A kind of automatic storage sample device | |
| CN220925425U (en) | Feeding device for belt conveyor | |
| CN108043626B (en) | Front swing disc equipment for spraying neodymium iron boron products | |
| CN207289358U (en) | Robot manipulator structure and foot-operated assembling device | |
| CN219025062U (en) | Sorting device with recognition function | |
| CN208037426U (en) | A kind of desk-top syringe needle detection device of weaving |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| TR01 | Transfer of patent right | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20211103 Address after: 510000 room 339, room 406, No. 1, Yichuang street, Huangpu District (Zhongxin Guangzhou Knowledge City), Guangzhou City, Guangdong Province Patentee after: Guangna Dakang (Guangzhou) Biotechnology Co.,Ltd. Address before: Room 1-5 / F, building B4, Wuhan National Biological Industry (Jiufeng innovation) base, 666 Gaoxin Avenue, Donghu New Technology Development Zone, Wuhan City, Hubei Province, 430000 Patentee before: WUHAN NANO DIAGNOSIS FOR HEALTH BIOTECHNOLOGY CO.,LTD. |