CN108619064A - A kind of tuber of multiflower knotweed Deacne pack and preparation method thereof - Google Patents
A kind of tuber of multiflower knotweed Deacne pack and preparation method thereof Download PDFInfo
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- CN108619064A CN108619064A CN201810874328.4A CN201810874328A CN108619064A CN 108619064 A CN108619064 A CN 108619064A CN 201810874328 A CN201810874328 A CN 201810874328A CN 108619064 A CN108619064 A CN 108619064A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/26—Aluminium; Compounds thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/965—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of inanimate origin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9794—Liliopsida [monocotyledons]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/98—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
- A61K8/981—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of mammals or bird
- A61K8/986—Milk; Derivatives thereof, e.g. butter
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/10—Anti-acne agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
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Abstract
The present invention provides a kind of tuber of multiflower knotweed Deacne pack and preparation method thereof, which includes:1)The rhizome of the tuber of multiflower knotweed is shredded, is then soaked in ethanol water, then system heat treatment is fractionated and is taken 80 85 DEG C of fraction, then removes the second alcohol and water in fraction to obtain tuber of multiflower knotweed extract;2)Thickener, glycerol and water are mixed and heated for the first time, it is subsequently added into bentonite, volcanic ash, sorbitan monostearate, methyl hydroxybenzoate, Pollen Astragali Melilotoidis (Pollen Astragali Sinici) end, milk, rat-tail grass meal, Jasmine powder, aloe mud and the tuber of multiflower knotweed extract and carries out secondary mixing, then vacuumizing degassing so that described tuber of multiflower knotweed Deacne pack facial mask is made has excellent anti-acne effect.
Description
Technical field
The present invention relates to facial masks, and in particular, to a kind of tuber of multiflower knotweed Deacne pack and preparation method thereof.
Background technology
Whelk, also known as acne are a kind of chronic inflammatory skins of pilosebaceous unit, are mainly apt to occur in green few
Year, it is very big to teen-age psychology and social influence, but tend to nature after puberty and mitigate or fully recover.Clinical manifestation is with good hair
With the characteristics of the pleomorphism skin lesions such as acne, papule, warts, the tubercle of face.
The non-inflammation skin of acne damage of acne shows as open and closed comedones.Closed comedones(Also known as hoary hair)Typical case
Skin lesion is the colour of skin papule of about 1 mm in size, without apparent hair follicle opening.Open comedones(Also known as blackhead)Show as dome-shaped mound
Rash is with the hair follicle opening significantly expanded.Acne, which further develop, can evolve into various inflammatory skin lesions, show as inflamed papules, purulence
Blister, tubercle and tumour.Inflamed papules take on a red color, and 1~5 millimeter of diameter differs;Warts is in the same size, has been filled with white purulence
Liquid;Tubercle diameter is more than 5 millimeters, and that touches has scleroma and feeling of pain;The position of tumour is deeper, is filled with the mixing of fester and blood
Object.These skin lesions can also merge to form big inflammatory patch and sinus etc..Inflammatory skin lesion usually left after subsiding pigmentation,
Erythema perstans, pitting or hypertrophic scar.Clinically according to acne lesions property and severity by acne be divided into 3 degree, 4
Grade:1 grade(Slightly):Only acne;2 grades(Moderate):In addition to acne, also some inflamed papules;3 grades(Moderate):In addition to acne,
Also more inflamed papules or warts;4 grades(Severe):In addition to having acne, inflamed papules and warts, go back nodosity, tumour or
Scar.
Currently, there are many therapy of acne, such as oral drugs, external used medicine, phototherapy, Chinese medicine.Oral drugs are to suffering from
The effect of somatic damage of person is larger, external used medicine and phototherapy is poor, and poor the effect of Chinese medicine.
Invention content
The object of the present invention is to provide a kind of tuber of multiflower knotweed Deacne pack and preparation method thereof, which there is excellent anti-acne to imitate
Fruit, while the production method has the advantages that process is simple and raw material is easy to get.
To achieve the goals above, the present invention provides a kind of production methods of tuber of multiflower knotweed Deacne pack, including:
1)The rhizome of the tuber of multiflower knotweed is shredded, is then soaked in ethanol water, then system heat treatment is fractionated and is taken
Then 80-85 DEG C of fraction removes the second alcohol and water in fraction to obtain tuber of multiflower knotweed extract;
2)Thickener, glycerol and water are mixed and heated for the first time, it is smooth single stearic to be subsequently added into bentonite, volcanic ash, sorb
Acid esters, methyl hydroxybenzoate, Pollen Astragali Melilotoidis (Pollen Astragali Sinici) end, milk, rat-tail grass meal, Jasmine powder, aloe mud fleece-flower root extract carry out
Then secondary mixing vacuumizes degassing so that tuber of multiflower knotweed Deacne pack is made.
Preferably, in step 1)In, in soaking process, solid-to-liquid ratio 1:10-20.
Preferably, in step 1)In, the volumetric concentration of ethyl alcohol is 75-85% in ethanol water.
Preferably, in step 1)In, the immersion meets the following conditions:Soaking temperature is 15-35 DEG C, soaking time 4-
8h。
Preferably, in step 1)In, the temperature of heat treatment is 100-105 DEG C.
Preferably, in step 2)In, heating is so that the temperature of system is maintained at 80-90 DEG C, and keeps the temperature to secondary mixing and tie
Beam.
Preferably, in step 2)In, the mixed time is 30-40min, and the time of secondary mixing is 2-4h.
Preferably, in step 2)In, bentonite, volcanic ash, sorbitan monostearate, methyl hydroxybenzoate, Chinese milk vetch flower
Powder, milk, rat-tail grass meal, Jasmine powder, aloe mud, tuber of multiflower knotweed extract, thickener, glycerol and water weight ratio be 30:
20-25:1.2-3:0.2-0.4:2.6-3.5:5-8:2-2.6:2.3-3.7:4-6:12-15:1-3:15-22:25-40.
Preferably, thickener is in methylcellulose, carboxyethyl cellulose, hydroxymethyl cellulose and ethyl cellulose
It is at least one.
The present invention provides a kind of tuber of multiflower knotweed Deacne pack, the tuber of multiflower knotweed Deacne pack is by above-mentioned preparation method makes
.
The present invention also provides a kind of tuber of multiflower knotweed Deacne pack, the tuber of multiflower knotweed Deacne pack is by above-mentioned preparation method makes
.
Through the above technical solutions, the present invention first extracts the tuber of multiflower knotweed to obtain extract, then by thickener, sweet
Oil, bentonite, volcanic ash etc. form the matrix of facial mask, finally add various nutritional ingredients, especially tuber of multiflower knotweed extract, and then make
Obtaining the facial mask has excellent anti-acne effect, and then shortens cleaning cycle.
Other features and advantages of the present invention will be described in detail in subsequent specific embodiment part.
Specific implementation mode
The specific implementation mode of the present invention is described in detail below.It should be understood that described herein specific
Embodiment is merely to illustrate and explain the present invention, and is not intended to restrict the invention.
The present invention provides a kind of production methods of tuber of multiflower knotweed Deacne pack, including:
1)The rhizome of the tuber of multiflower knotweed is subjected to boiling, is then extracted by ethyl acetate, then removes ethyl acetate to obtain head
Black extract;
2)Thickener, glycerol and water are mixed and heated for the first time, it is smooth single stearic to be subsequently added into bentonite, volcanic ash, sorb
Acid esters, methyl hydroxybenzoate, Pollen Astragali Melilotoidis (Pollen Astragali Sinici) end, milk, rat-tail grass meal, Jasmine powder, aloe mud fleece-flower root extract carry out
Then secondary mixing vacuumizes degassing so that tuber of multiflower knotweed Deacne pack is made.
The present invention provides a kind of production methods of tuber of multiflower knotweed Deacne pack, including:
1)The rhizome of the tuber of multiflower knotweed is shredded, is then soaked in ethanol water, then system heat treatment is fractionated and is taken
Then 80-85 DEG C of fraction removes the second alcohol and water in fraction to obtain tuber of multiflower knotweed extract;
2)Thickener, glycerol and water are mixed and heated for the first time, it is smooth single stearic to be subsequently added into bentonite, volcanic ash, sorb
Acid esters, methyl hydroxybenzoate, Pollen Astragali Melilotoidis (Pollen Astragali Sinici) end, milk, rat-tail grass meal, Jasmine powder, aloe mud fleece-flower root extract carry out
Then secondary mixing vacuumizes degassing so that tuber of multiflower knotweed Deacne pack is made.
In the present invention, the raw material dosage in soaking process can select in a wide range, but in order to further carry
The anti-acne effect of high facial mask, it is preferable that in step 1)In, in soaking process, solid-to-liquid ratio 1:10-20.
In the present invention, the concentration of ethanol water can select in a wide range, but in order to further increase face
The anti-acne effect of film, it is preferable that in step 1)In, the volumetric concentration of ethyl alcohol is 75-85% in ethanol water.
In the step 1 of the present invention)In, the temperature of heat treatment can select in a wide range, but in order to further carry
The anti-acne effect of high facial mask, it is preferable that in step 1)In, the temperature of heat treatment is 100-105 DEG C.
In the step 1 of the present invention)In, the condition of immersion can select in a wide range, but in order to further increase
The anti-acne effect of facial mask, it is preferable that in step 1)In, the immersion meets the following conditions:Soaking temperature is 15-35 DEG C, is impregnated
Time is 4-8h.
In the step 2 of the present invention)In, the condition of heating can select in a wide range, but in order to further increase
The anti-acne effect of facial mask, it is preferable that in step 2)In, heating is so that the temperature of system is maintained at 80-90 DEG C, and keeps the temperature to secondary
Mixing terminates.
In the step 2 of the present invention)In, the condition of heating can select in a wide range, but in order to further increase
The anti-acne effect of facial mask, it is preferable that in step 2)In, the time mixed for the first time is 30-40min, and the time of secondary mixing is 2-
4h。
In the step 2 of the present invention)In, the dosage of each material can select in a wide range, but in order to further carry
The anti-acne effect of high facial mask, it is preferable that in step 2)In, bentonite, volcanic ash, sorbitan monostearate, methyl hydroxybenzoate,
Pollen Astragali Melilotoidis (Pollen Astragali Sinici) end, milk, rat-tail grass meal, Jasmine powder, aloe mud, tuber of multiflower knotweed extract, thickener, glycerol and water weight
Than being 30:20-25:1.2-3:0.2-0.4:2.6-3.5:5-8:2-2.6:2.3-3.7:4-6:12-15:1-3:15-22:25-
40。
In the step 2 of the present invention)In, the type of thickener can select in a wide range, but in order to further carry
The anti-acne effect of high facial mask, it is preferable that thickener is selected from methylcellulose, carboxyethyl cellulose, hydroxymethyl cellulose and ethyl
At least one of cellulose.
The present invention provides a kind of tuber of multiflower knotweed Deacne pack, the tuber of multiflower knotweed Deacne pack is by above-mentioned production method makes
.
The present invention will be described in detail by way of examples below.
Embodiment 1
1)The rhizome of the tuber of multiflower knotweed is shredded, is then soaked in the ethanol water that volumetric concentration is 80%(Solid-to-liquid ratio is 1:15, leaching
It is 25 DEG C to steep temperature, soaking time 6h), then system is heat-treated(103℃)It is fractionated and is taken 83 DEG C of fraction, so
The second alcohol and water in fraction is removed afterwards to obtain tuber of multiflower knotweed extract;
2)By thickener(Methylcellulose), glycerol and water carry out first mixing 35min and be heated to 5 DEG C and keep the temperature, then plus
Enter bentonite, volcanic ash, sorbitan monostearate, methyl hydroxybenzoate, Pollen Astragali Melilotoidis (Pollen Astragali Sinici) end, milk, rat-tail grass meal, Jasmine
Powder, aloe mud fleece-flower root extract carry out secondary mixing 3h(Bentonite, volcanic ash, sorbitan monostearate, Metagin
Ester, Pollen Astragali Melilotoidis (Pollen Astragali Sinici) end, milk, rat-tail grass meal, Jasmine powder, aloe mud, tuber of multiflower knotweed extract, thickener, glycerol and water
Weight ratio is 30:23:1.8:0.3:3:7:2.3:2.9:5:13:2:19:30), degassing is then vacuumized so that tuber of multiflower knotweed anti-acne is made
Facial mask A1.
Embodiment 2
1)The rhizome of the tuber of multiflower knotweed is shredded, is then soaked in the ethanol water that volumetric concentration is 75%(Solid-to-liquid ratio is 1:10, leaching
Steep 15 DEG C of temperature, soaking time 4h), then system is heat-treated(100℃)It is fractionated and is taken 80 DEG C of fraction, then
The second alcohol and water in fraction is removed to obtain tuber of multiflower knotweed extract;
2)By thickener(Hydroxymethyl cellulose), glycerol and water carry out first mixing 30min and be heated to 80 DEG C and keep the temperature, then
Bentonite, volcanic ash, sorbitan monostearate, methyl hydroxybenzoate, Pollen Astragali Melilotoidis (Pollen Astragali Sinici) end, milk, rat-tail grass meal, jasmine is added
Pollen end, aloe mud fleece-flower root extract carry out secondary mixing 2h(Bentonite, volcanic ash, sorbitan monostearate, nipalgin
Methyl esters, Pollen Astragali Melilotoidis (Pollen Astragali Sinici) end, milk, rat-tail grass meal, Jasmine powder, aloe mud, tuber of multiflower knotweed extract, thickener, glycerol and water
Weight ratio be 30:20:1.2:0.2:2.6:5:2:2.3:4:12:1:15:25), then vacuumize degassing and dispelled so that the tuber of multiflower knotweed is made
Acne facial mask A2.
Embodiment 3
1)The rhizome of the tuber of multiflower knotweed is shredded, is then soaked in the ethanol water that volumetric concentration is 85%(Solid-to-liquid ratio is 1:20, leaching
It is 35 DEG C to steep temperature, soaking time 8h), then system is heat-treated(105℃)It is fractionated and takes 80-85 DEG C to evaporate
Point, the second alcohol and water in fraction is then removed to obtain tuber of multiflower knotweed extract;
2)By thickener(Ethyl cellulose), glycerol and water carry out first mixing 40min and be heated to 90 DEG C and keep the temperature, then plus
Enter bentonite, volcanic ash, sorbitan monostearate, methyl hydroxybenzoate, Pollen Astragali Melilotoidis (Pollen Astragali Sinici) end, milk, rat-tail grass meal, Jasmine
Powder, aloe mud fleece-flower root extract carry out secondary mixing 4h(Bentonite, volcanic ash, sorbitan monostearate, Metagin
Ester, Pollen Astragali Melilotoidis (Pollen Astragali Sinici) end, milk, rat-tail grass meal, Jasmine powder, aloe mud, tuber of multiflower knotweed extract, thickener, glycerol and water
Weight ratio is 30:25:3:0.4:3.5:8:2.6:3.7:6:15:3:22:40), degassing is then vacuumized so that tuber of multiflower knotweed anti-acne is made
Facial mask A3.
Comparative example 1
It carries out that facial mask B1 is made according to the method for embodiment 1, unlike, step 2)In be not added with tuber of multiflower knotweed extract.
Application examples 1
Choose 2 grades of patients with acne, 3 grades of patients with acne use above-mentioned facial mask(Primary, each surface application 20- is used every two days
30min), until speckle desalination disappears, then count healing time.
Table 1
The preferred embodiment of the present invention has been described above in detail, still, the tool during present invention is not limited to the embodiments described above
Body details can carry out a variety of simple variants, these letters to technical scheme of the present invention within the scope of the technical concept of the present invention
Monotropic type all belongs to the scope of protection of the present invention.
It is further to note that specific technical features described in the above specific embodiments, in not lance
In the case of shield, can be combined by any suitable means, in order to avoid unnecessary repetition, the present invention to it is various can
The combination of energy no longer separately illustrates.
In addition, various embodiments of the present invention can be combined randomly, as long as it is without prejudice to originally
The thought of invention, it should also be regarded as the disclosure of the present invention.
Claims (5)
1. a kind of preparation method of tuber of multiflower knotweed Deacne pack, which is characterized in that including:
1)The rhizome of the tuber of multiflower knotweed is shredded, is then soaked in ethanol water, then system heat treatment is fractionated and is taken
Then 80-85 DEG C of fraction removes the second alcohol and water in fraction to obtain tuber of multiflower knotweed extract;
2)Thickener, glycerol and water are mixed and heated for the first time, it is smooth single stearic to be subsequently added into bentonite, volcanic ash, sorb
Acid esters, methyl hydroxybenzoate, Pollen Astragali Melilotoidis (Pollen Astragali Sinici) end, milk, rat-tail grass meal, Jasmine powder, aloe mud and the tuber of multiflower knotweed extract
Secondary mixing is carried out, then vacuumizes degassing so that the tuber of multiflower knotweed Deacne pack is made.
2. preparation method according to claim 1, wherein in step 1)In:
In the soaking process, solid-to-liquid ratio 1:10-20;
The volumetric concentration of ethyl alcohol is 75-85% in the ethanol water;
The immersion meets the following conditions:Soaking temperature is 15-35 DEG C, soaking time 4-8h;
The temperature of the heat treatment is 100-105 DEG C.
3. manufacturing method according to claim 1, wherein in step 2)In:
The heating is so that the temperature of system is maintained at 80-90 DEG C, and keeps the temperature to the secondary mixing and terminate;
The time mixed for the first time is 30-40min, and the time of the secondary mixing is 2-4h.
4. preparation method according to claim 1, wherein in step 2)In, the smooth list of the bentonite, volcanic ash, sorb
Stearate, methyl hydroxybenzoate, Pollen Astragali Melilotoidis (Pollen Astragali Sinici) end, milk, rat-tail grass meal, Jasmine powder, aloe mud, tuber of multiflower knotweed extract,
Thickener, glycerol and water weight ratio be 30:20-25:1.2-3:0.2-0.4:2.6-3.5:5-8:2-2.6:2.3-3.7:4-
6:12-15:1-3:15-22:25-40.
5. preparation method according to claim 1, wherein the thickener be selected from methylcellulose, carboxyethyl cellulose,
At least one of hydroxymethyl cellulose and ethyl cellulose.
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CN201810874328.4A CN108619064A (en) | 2018-08-03 | 2018-08-03 | A kind of tuber of multiflower knotweed Deacne pack and preparation method thereof |
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CN201810874328.4A CN108619064A (en) | 2018-08-03 | 2018-08-03 | A kind of tuber of multiflower knotweed Deacne pack and preparation method thereof |
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Application publication date: 20181009 |