CN108652997A - Asian puccoon Deacne pack and preparation method thereof - Google Patents

Asian puccoon Deacne pack and preparation method thereof Download PDF

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Publication number
CN108652997A
CN108652997A CN201810850816.1A CN201810850816A CN108652997A CN 108652997 A CN108652997 A CN 108652997A CN 201810850816 A CN201810850816 A CN 201810850816A CN 108652997 A CN108652997 A CN 108652997A
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preparation
asian puccoon
boiling
leaf powder
deacne pack
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Chinese (zh)
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余芳
彭姝文
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Individual
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A61K8/26Aluminium; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A61K8/23Sulfur; Selenium; Tellurium; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/494Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
    • A61K8/4946Imidazoles or their condensed derivatives, e.g. benzimidazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4973Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/965Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of inanimate origin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9789Magnoliopsida [dicotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/98Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
    • A61K8/987Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of species other than mammals or birds
    • A61K8/988Honey; Royal jelly, Propolis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/10Anti-acne agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin

Abstract

The invention discloses a kind of Asian puccoon Deacne pack and preparation method thereof, which includes:1)The rhizome of Asian puccoon is subjected to boiling, is then extracted by acetone, then removes acetone to obtain Radix Arnebiae extract;2)Thickener, glycerol and water are mixed and heated for the first time, it is subsequently added into bentonite, volcanic ash, sorbitan monostearate, allantoin, mung bean flour, honey, tea leaf powder, Cosan, dried peppermint leaf powder mud and Radix Arnebiae extract and carries out secondary mixing, then vacuumize degassing so that Asian puccoon Deacne pack is made.The facial mask has the advantages that anti-acne effect is fast, while the preparation method has the advantages that process is simple and raw material is easy to get.

Description

Asian puccoon Deacne pack and preparation method thereof
Technical field
The present invention relates to facial masks, and in particular, to a kind of Asian puccoon Deacne pack and preparation method thereof.
Background technology
Whelk, also known as acne are a kind of chronic inflammatory skins of pilosebaceous unit, are mainly apt to occur in green few Year, it is very big to teen-age psychology and social influence, but tend to nature after puberty and mitigate or fully recover.Clinical manifestation is with good hair With the characteristics of the pleomorphism skin lesions such as acne, papule, warts, the tubercle of face.
The non-inflammation skin of acne damage of acne shows as open and closed comedones.Closed comedones(Also known as hoary hair)Typical case Skin lesion is the colour of skin papule of about 1 mm in size, without apparent hair follicle opening.Open comedones(Also known as blackhead)Show as dome-shaped mound Rash is with the hair follicle opening significantly expanded.Acne, which further develop, can evolve into various inflammatory skin lesions, show as inflamed papules, purulence Blister, tubercle and tumour.Inflamed papules take on a red color, and 1~5 millimeter of diameter differs;Warts is in the same size, has been filled with white purulence Liquid;Tubercle diameter is more than 5 millimeters, and that touches has scleroma and feeling of pain;The position of tumour is deeper, is filled with the mixing of fester and blood Object.These skin lesions can also merge to form big inflammatory patch and sinus etc..Inflammatory skin lesion usually left after subsiding pigmentation, Erythema perstans, pitting or hypertrophic scar.Clinically according to acne lesions property and severity by acne be divided into 3 degree, 4 Grade:1 grade(Slightly):Only acne;2 grades(Moderate):In addition to acne, also some inflamed papules;3 grades(Moderate):In addition to acne, Also more inflamed papules or warts;4 grades(Severe):In addition to having acne, inflamed papules and warts, go back nodosity, tumour or Scar.
Currently, there are many therapy of acne, such as oral drugs, external used medicine, phototherapy, Chinese medicine.Oral drugs are to suffering from The effect of somatic damage of person is larger, external used medicine and phototherapy is poor, and poor the effect of Chinese medicine.
Invention content
The object of the present invention is to provide a kind of Asian puccoon Deacne pack and preparation method thereof, which has anti-acne effect fast Advantage, while the preparation method has the advantages that process is simple and raw material is easy to get.
To achieve the goals above, the present invention provides a kind of preparation methods of Asian puccoon Deacne pack, including:
1)The rhizome of Asian puccoon is subjected to boiling, is then extracted by acetone, then removes acetone to obtain Radix Arnebiae extract;
2)Thickener, glycerol and water are mixed and heated for the first time, it is smooth single stearic to be subsequently added into bentonite, volcanic ash, sorb Acid esters, allantoin, mung bean flour, honey, tea leaf powder, Cosan, dried peppermint leaf powder mud and Radix Arnebiae extract carry out secondary mixing, then Degassing is vacuumized so that Asian puccoon Deacne pack is made.
Preferably, in step 1)In, during boiling, solid-to-liquid ratio 1:10-20.
Preferably, in step 1)In, boiling meets the following conditions:Boiling temperature is 110-120 DEG C, and the boiling time is 40- 60min。
Preferably, in step 1)In, extraction is carried out by the way of multitple extraction, in each extraction process, object to be extracted Volume ratio with extractant is 1:2-4.
Preferably, in step 1)In, the number of multitple extraction is 3-5 times.
Preferably, in step 2)In, heating is so that the temperature of system is maintained at 80-90 DEG C, and keeps the temperature to secondary mixing and tie Beam.
Preferably, in step 2)In, the time mixed for the first time is 30-40min, and the time of secondary mixing is 2-4h.
Preferably, in step 2)In, bentonite, volcanic ash, sorbitan monostearate, allantoin, mung bean flour, honey, Tea leaf powder, Cosan, dried peppermint leaf powder mud, Radix Arnebiae extract, thickener, glycerol and water weight ratio be 30:20-25:1.2-3: 0.1-0.3:3-5:1.5-4:3-5:0.5-0.8:7-9:15-20:1-3:15-22:25-40.
Preferably, thickener is in methylcellulose, carboxyethyl cellulose, hydroxymethyl cellulose and ethyl cellulose It is at least one.
The present invention also provides a kind of Asian puccoon Deacne pack, the Asian puccoon Deacne pack is by prepared by above-mentioned preparation method .
Through the above technical solutions, the present invention first extracts Asian puccoon to obtain extract, then by thickener, sweet Oil, bentonite, volcanic ash etc. form the matrix of facial mask, finally add various nutritional ingredients, especially Radix Arnebiae extract, and then make Obtaining the facial mask has excellent anti-acne effect, and then shortens the anti-acne period.
Other features and advantages of the present invention will be described in detail in subsequent specific embodiment part.
Specific implementation mode
The specific implementation mode of the present invention is described in detail below.It should be understood that described herein specific Embodiment is merely to illustrate and explain the present invention, and is not intended to restrict the invention.
The present invention provides a kind of preparation methods of Asian puccoon Deacne pack, including:
1)The rhizome of Asian puccoon is subjected to boiling, is then extracted by acetone, then removes acetone to obtain Radix Arnebiae extract;
2)Thickener, glycerol and water are mixed and heated for the first time, it is smooth single stearic to be subsequently added into bentonite, volcanic ash, sorb Acid esters, allantoin, mung bean flour, honey, tea leaf powder, Cosan, dried peppermint leaf powder mud and Radix Arnebiae extract carry out secondary mixing, then Degassing is vacuumized so that Asian puccoon Deacne pack is made.
In the present invention, the raw material dosage during boiling can select in a wide range, but in order to further carry The anti-acne effect of high facial mask, it is preferable that in step 1)In, during boiling, solid-to-liquid ratio 1:10-20.
In the present invention, boiling condition can select in a wide range, but in order to further increase the anti-acne of facial mask Effect, it is preferable that in step 1)In, boiling meets the following conditions:Boiling temperature is 110-120 DEG C, and the boiling time is 40- 60min。
In the present invention, the actual conditions of extraction can select in a wide range, but in order to further increase extraction Effect, it is preferable that in step 1)In, extraction is carried out by the way of multitple extraction, in each extraction process, object to be extracted and extraction It is 1 to take the volume ratio of agent:2-4;It is highly preferred that in step 1)In, the number of multitple extraction is 3-5 times.
In the step 2 of the present invention)In, the condition of heating can select in a wide range, but in order to further increase The anti-acne effect of facial mask obtained, it is preferable that in step 2)In, heating is so that the temperature of system is maintained at 80-90 DEG C, and keeps the temperature Terminate to secondary mixing.
In the step 2 of the present invention)In, mixed condition can select in a wide range, but in order to further increase The anti-acne effect of facial mask obtained, it is preferable that in step 2)In, the mixed time is 30-40min, and the time of secondary mixing is 2-4h。
In the step 2 of the present invention)In, the dosage of each material can select in a wide range, but in order to further carry The anti-acne effect of facial mask made from height, it is preferable that in step 2)In, bentonite, volcanic ash, sorbitan monostearate, allantois Element, mung bean flour, honey, tea leaf powder, Cosan, dried peppermint leaf powder mud, Radix Arnebiae extract, thickener, glycerol and water weight ratio be 30:20-25:1.2-3:0.1-0.3:3-5:1.5-4:3-5:0.5-0.8:7-9:15-20:1-3:15-22:25-40.
In the step 2 of the present invention)In, the specific type of thickener can select in a wide range, but in order into one Step improves the anti-acne effect of facial mask obtained, it is preferable that it is fine that thickener is selected from methylcellulose, carboxyethyl cellulose, methylol At least one of dimension element and ethyl cellulose.
The present invention also provides a kind of Asian puccoon Deacne pack, the Asian puccoon Deacne pack is by prepared by above-mentioned preparation method .
The present invention will be described in detail by way of examples below.
Embodiment 1
1)The rhizome of Asian puccoon is subjected to boiling(Solid-to-liquid ratio is 1:15, boiling temperature is 115 DEG C, and the boiling time is 50min), then Multitple extraction is carried out by acetone 4 times(In each extraction process, the volume ratio of object and extractant to be extracted is 1:3), then go Except acetone is to obtain Radix Arnebiae extract;
2)By thickener(Hydroxymethyl cellulose), glycerol and water carry out first mixing 35min and be heated to 85 DEG C and keep the temperature, then Bentonite, volcanic ash, sorbitan monostearate, allantoin, mung bean flour, honey, tea leaf powder, Cosan, dried peppermint leaf powder is added Mud and Radix Arnebiae extract carry out secondary mixing 3h(Bentonite, volcanic ash, sorbitan monostearate, allantoin, mung bean flour, bee Honey, tea leaf powder, Cosan, dried peppermint leaf powder mud, Radix Arnebiae extract, thickener, glycerol and water weight ratio be 30:23:1.8: 0.2:4:3:4:0.7:8:18:2:20:30), degassing is then vacuumized so that Asian puccoon Deacne pack A1 is made.
Embodiment 2
1)The rhizome of Asian puccoon is subjected to boiling(Solid-to-liquid ratio is 1:10, boiling temperature is 110 DEG C, and the boiling time is 40min), then Multitple extraction is carried out by acetone 3 times(In each extraction process, the volume ratio of object and extractant to be extracted is 1:2), then go Except acetone is to obtain Radix Arnebiae extract;
2)By thickener(Methylcellulose), glycerol and water carry out first mixing 30min and be heated to 80 DEG C and keep the temperature, then plus Enter bentonite, volcanic ash, sorbitan monostearate, allantoin, mung bean flour, honey, tea leaf powder, Cosan, dried peppermint leaf powder mud Secondary mixing 2h is carried out with Radix Arnebiae extract(Bentonite, volcanic ash, sorbitan monostearate, allantoin, mung bean flour, honey, Tea leaf powder, Cosan, dried peppermint leaf powder mud, Radix Arnebiae extract, thickener, glycerol and water weight ratio be 30:20:1.2:0.1:3: 1.5:3:0.5:7:15:1:15:25), degassing is then vacuumized so that Asian puccoon Deacne pack A2 is made.
Embodiment 3
1)The rhizome of Asian puccoon is subjected to boiling(Solid-to-liquid ratio is 1:20, boiling temperature is 120 DEG C, and the boiling time is 60min), then Multitple extraction is carried out by acetone 3-5 times(In each extraction process, the volume ratio of object and extractant to be extracted is 1:2-4), so Removal acetone is to obtain Radix Arnebiae extract afterwards;
2)By thickener(Carboxyethyl cellulose), glycerol and water carry out first mixing 40min and be heated to 90 DEG C and keep the temperature, then Bentonite, volcanic ash, sorbitan monostearate, allantoin, mung bean flour, honey, tea leaf powder, Cosan, dried peppermint leaf powder is added Mud and Radix Arnebiae extract carry out secondary mixing 4h(Bentonite, volcanic ash, sorbitan monostearate, allantoin, mung bean flour, bee Honey, tea leaf powder, Cosan, dried peppermint leaf powder mud, Radix Arnebiae extract, thickener, glycerol and water weight ratio be 30:25:3:0.3: 5:4:5:0.8:9:20:3:22:40), degassing is then vacuumized so that Asian puccoon Deacne pack A3 is made.
Comparative example 1
It carries out that facial mask B1 is made according to the method for embodiment 1, unlike, step 2)In be not added with Radix Arnebiae extract.
Application examples
Choose 2 grades of patients with acne, 3 grades of patients with acne use above-mentioned facial mask(Primary, each surface application 20- is used every two days 30min), until speckle desalination disappears, then count healing time.
Table 1
The preferred embodiment of the present invention has been described above in detail, still, the tool during present invention is not limited to the embodiments described above Body details can carry out a variety of simple variants, these letters to technical scheme of the present invention within the scope of the technical concept of the present invention Monotropic type all belongs to the scope of protection of the present invention.
It is further to note that specific technical features described in the above specific embodiments, in not lance In the case of shield, can be combined by any suitable means, in order to avoid unnecessary repetition, the present invention to it is various can The combination of energy no longer separately illustrates.
In addition, various embodiments of the present invention can be combined randomly, as long as it is without prejudice to originally The thought of invention, it should also be regarded as the disclosure of the present invention.

Claims (10)

1. a kind of preparation method of Asian puccoon Deacne pack, which is characterized in that including:
1)The rhizome of Asian puccoon is subjected to boiling, is then extracted by acetone, then removes acetone to obtain Radix Arnebiae extract;
2)Thickener, glycerol and water are mixed and heated for the first time, it is smooth single stearic to be subsequently added into bentonite, volcanic ash, sorb Acid esters, allantoin, mung bean flour, honey, tea leaf powder, Cosan, dried peppermint leaf powder mud and the Radix Arnebiae extract carry out secondary mixing, Then degassing is vacuumized so that the Asian puccoon Deacne pack is made.
2. preparation method according to claim 1, wherein in step 1)In, during the boiling, solid-to-liquid ratio 1: 10-20。
3. preparation method according to claim 1, wherein in step 1)In, the boiling meets the following conditions:Boiling temperature Degree is 110-120 DEG C, and the boiling time is 40-60min.
4. preparation method according to claim 1, wherein in step 1)In, the extraction is by the way of multitple extraction It carries out, in each extraction process, the volume ratio of object and extractant to be extracted is 1:2-4.
5. preparation method according to claim 4, wherein in step 1)In, the number of the multitple extraction is 3-5 times.
6. preparation method according to claim 1, wherein in step 2)In, the heating is so that the temperature of system is kept At 80-90 DEG C, and keeps the temperature to the secondary mixing and terminate.
7. preparation method according to claim 1, wherein in step 2)In, the time mixed for the first time is 30- The time of 40min, the secondary mixing are 2-4h.
8. preparation method according to claim 1, wherein in step 2)In, the smooth list of the bentonite, volcanic ash, sorb Stearate, allantoin, mung bean flour, honey, tea leaf powder, Cosan, dried peppermint leaf powder mud, Radix Arnebiae extract, thickener, glycerine and The weight ratio of water is 30:20-25:1.2-3:0.1-0.3:3-5:1.5-4:3-5:0.5-0.8:7-9:15-20:1-3:15-22: 25-40。
9. preparation method according to claim 1, wherein the thickener be selected from methylcellulose, carboxyethyl cellulose, At least one of hydroxymethyl cellulose and ethyl cellulose.
10. a kind of Asian puccoon Deacne pack, which is characterized in that the Asian puccoon Deacne pack passes through any one of claim 1-9 The preparation method is prepared.
CN201810850816.1A 2018-07-29 2018-07-29 Asian puccoon Deacne pack and preparation method thereof Pending CN108652997A (en)

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Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1150018A (en) * 1995-11-15 1997-05-21 李�杰 Multifunctional Chinese medicine facial mask and prescription
CN101744972A (en) * 2008-12-19 2010-06-23 林学荣 Facemask for treating acne and preparation method thereof
CN104042543A (en) * 2014-06-03 2014-09-17 舒欣 Anti-acne mask and making method thereof
CN105343379A (en) * 2015-12-17 2016-02-24 济南舜祥医药科技有限公司 Acne removal facial mask
CN105663004A (en) * 2016-02-26 2016-06-15 李海丽 Flos chrysanthemi indici traditional Chinese medicine mask and preparation method
CN106177408A (en) * 2016-07-20 2016-12-07 北京康盛源泰科技有限公司 A kind of resisting skin allergy Chinese medicine composition, Chinese medicine preparation, facial film, preparation method
CN107648296A (en) * 2017-08-18 2018-02-02 合肥丰洁生物科技有限公司 A kind of preparation method of Radix Arnebiae extract

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1150018A (en) * 1995-11-15 1997-05-21 李�杰 Multifunctional Chinese medicine facial mask and prescription
CN101744972A (en) * 2008-12-19 2010-06-23 林学荣 Facemask for treating acne and preparation method thereof
CN104042543A (en) * 2014-06-03 2014-09-17 舒欣 Anti-acne mask and making method thereof
CN105343379A (en) * 2015-12-17 2016-02-24 济南舜祥医药科技有限公司 Acne removal facial mask
CN105663004A (en) * 2016-02-26 2016-06-15 李海丽 Flos chrysanthemi indici traditional Chinese medicine mask and preparation method
CN106177408A (en) * 2016-07-20 2016-12-07 北京康盛源泰科技有限公司 A kind of resisting skin allergy Chinese medicine composition, Chinese medicine preparation, facial film, preparation method
CN107648296A (en) * 2017-08-18 2018-02-02 合肥丰洁生物科技有限公司 A kind of preparation method of Radix Arnebiae extract

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
肖子英: "《中国药物化妆品》", 31 March 1992, 中国医药科学出版社 *
裘炳毅: "《现代化妆品科学与技术》", 31 March 2016, 中国轻工业出版社 *

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Application publication date: 20181016