CN108619020A - A kind of facial mask and preparation method thereof containing Myoporum bontiodes extract - Google Patents
A kind of facial mask and preparation method thereof containing Myoporum bontiodes extract Download PDFInfo
- Publication number
- CN108619020A CN108619020A CN201810607370.XA CN201810607370A CN108619020A CN 108619020 A CN108619020 A CN 108619020A CN 201810607370 A CN201810607370 A CN 201810607370A CN 108619020 A CN108619020 A CN 108619020A
- Authority
- CN
- China
- Prior art keywords
- facial mask
- extract
- component
- myoporum bontiodes
- myoporum
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/74—Biological properties of particular ingredients
- A61K2800/78—Enzyme modulators, e.g. Enzyme agonists
- A61K2800/782—Enzyme inhibitors; Enzyme antagonists
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
- A61K2800/805—Corresponding aspects not provided for by any of codes A61K2800/81 - A61K2800/95
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Dermatology (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Cosmetics (AREA)
Abstract
The present invention provides a kind of facial mask containing Myoporum bontiodes extract, including mask substrate and facial mask essence, and facial mask essence includes beta glucan, chitosan oligosaccharide, Cer NP, hyaluronic acid, allantoin, polypeptide and Myoporum bontiodes extract etc..The preparation method of the facial mask includes the following steps：1) preparation of Myoporum bontiodes extract；2) prepared by the facial mask that contains Myoporum bontiodes extract.Facial mask main active produced by the present invention is the extract of natural plants Myoporum bontiodes, skin is not stimulated, it will not cause to rely on, have effects that skin whitening, moisturizing, deep water supplement and moisturizing beauty treatment, this facial mask, which is used for a long time, can calm down wrinkle, repair damaged skin and whitening spot-removing, reach anti-aging, improves the effect of skin elasticity.Raw material sources of the present invention are easy to obtain extensively, and preparation process is simple, production easy to process.
Description
Technical field
The invention belongs to daily chemicals technical field, especially a kind of facial mask containing Myoporum bontiodes extract and its preparation
Method.
Background technology
In personal nursing class daily chemical products, facial mask is a kind of ideal facial-care product being loved by consumers.Mesh
Preceding mask product on the market has very much, has whitening mask, moisture saver mask, MASQUE APAISANT HYDRATANT etc., but the effect of many facial masks is simultaneously
Non- some chemical substances can cause the side effects such as skin of face allergy caused by natural component, more have severe patient to further relate to weight
Metal is exceeded.And consumer can collect whitening and moisture-keeping functions again for pure natural plant ingredients, especially pure natural plant ingredients
There is great demand with the facial mask of the whole body.Chinese herbal medicine is with a long history, of long standing and well established, is developed naturally using plant herbal medicine in China
Active cosmetic has an advantageous condition, produces the natural cosmetics with Chinese characteristic, be China's cosmetics scientific research and
The Research Emphasis of manufacturer.
Myoporum bontiodes (Myoporum bontioides, A.Gray) be a kind of mangrove associates being under the jurisdiction of Myoporaceae and
Perennial evergreen shrubs or arbor are a kind of China uniquely Myoporum plants, on edges such as Guangdong, Guangxi, Hainan, Fujian
Haiti area resource is abundant, and can be with growing and cultivation, greening garden.Contain about 20% mannitol, sweet dew in Myoporum bontiodes
Sugar alcohol can draw a large amount of moisture, no matter all have humectant under low humidity or high humidity, be small molecule type
Natural moisture preserving raw material；Contain about 8~10% flavone compound in Myoporum bontiodes, flavone compound inhibits tyrosinase
Best natural material, skin whitening can be played the role of.
From the foregoing, it will be observed that containing a large amount of effective active composition in Myoporum bontiodes, therefore facial mask is made in Myoporum bontiodes extract, it is right
Skin does not stimulate, and will not cause to rely on.Work(of the facial mask with skin whitening, moisturizing, deep water supplement and moisturizing beauty treatment is used for a long time
Effect has extensively using value and potentiality.
Invention content
The purpose of the present invention is to provide a kind of facial mask and preparation method thereof containing Myoporum bontiodes extract, the facial mask are main
The effect of active constituent is natural plant extracts, skin whitening, moisturizing, deep water supplement and moisturizing beauty treatment is notable, and raw material sources are wide
General, preparation method is simple.
Above-mentioned purpose to realize the present invention, the present invention adopt the following technical scheme that：
A kind of facial mask containing Myoporum bontiodes extract, including mask substrate and the facial mask essence containing Myoporum bontiodes extract
Liquid, facial mask essence are made of component A, B, C, D, E, Myoporum bontiodes extract, Tween-80 and water.Myoporum bontiodes extract is to skin
It can play the role of whitening, moisturizing.Tween-80 can increase effective in facial mask essence as a kind of surfactant
Dissolution degree of the ingredient in facial mask essence, makes the active ingredient in facial mask essence be easier to be absorbed by the skin.
As a preferred embodiment, in facial mask essence component A by EDETATE SODIUM, beta glucan, chitosan oligosaccharide and neural acyl
Amine 3 forms；Component B is made of panthenol, hyaluronic acid and allantoin；Component C is glycerine；Component D is crosslinked poly- by polyacrylate
Close object -6, methyl glucose sugar alcohol polyethers -10, Cremophor RH40, PEG-12 dimethyl silicone polymers 1016, glycine betaine
It is formed with methyl hydroxybenzoate；Component E is made of polypeptide and xanthans.Beta glucan, chitosan oligosaccharide and Cer NP have moisturizing, suppression
Harmful bacteria growth, anti-aging, reparation skin barrier and sun-proof effect processed.Panthenol, hyaluronic acid and allantoin have moisturizing, resist
Inflammation, effect that is anti-aging, making skin emolliency.Glycerine has the function of moisturizing.Polyacrylate cross-linked polymer -6, methyl Portugal
Grape sugar alcohol polyethers -10, PEG-40 rilanit specials, PEG-12 dimethyl silicone polymers 1016, glycine betaine and methyl hydroxybenzoate play
The effects that anti-corrosion, thickening, emulsification.Polypeptide has the effects that anti-aging, smoothing wrinkle, removal red blood silk.
As a preferred embodiment, facial mask essence is made of following raw material and weight proportion：
Component A：EDETATE SODIUM 0.02~0.06%, beta glucan 0.02~0.06%, chitosan oligosaccharide 0.05~0.1%, god
Through amide 3 0.1~0.2%；
Component B：Panthenol 0.4~1.2%, hyaluronic acid 0.02~0.1%, allantoin 0.05~0.15%；
Component C：Glycerine 1~2%；
Component D：By polyacrylate cross-linked polymer -6 0.06~0.18%, methyl glucose sugar alcohol polyethers -10 1~
2%, Cremophor RH40 0.001~0.002%, PEG-12 dimethyl silicone polymers 1,016 0.1~0.2%, beet
Alkali 1~2%, methyl hydroxybenzoate 0.05~0.15%；
Component E：Polypeptide 0.25~0.75% and xanthans 0.15~0.45%；
Myoporum bontiodes extract 1~3%, Tween-80 0.05~0.1% and water surplus.
As a preferred embodiment, the facial mask essence is made of following raw material and weight proportion：
Component A：EDETATE SODIUM 0.04%, beta glucan 0.03%, chitosan oligosaccharide 0.08%, Cer NP 0.2%；
Component B：Panthenol 1%, hyaluronic acid 0.08%, allantoin 0.1%；
Component C：Glycerine 1.5%；
Component D：By polyacrylate cross-linked polymer -6 0.1%, methyl glucose sugar alcohol polyethers -10 1%, PEG-40
Rilanit special 0.002%, PEG-12 dimethyl silicone polymers 1,016 0.15%, glycine betaine 1.5%, methyl hydroxybenzoate 0.1%；
Component E：Polypeptide 0.5% and xanthans 0.3%；
Myoporum bontiodes extract 2%, Tween-80 0.07% and water surplus.
As a preferred embodiment, polypeptide is oligopeptides -1, oligopeptides -6 or hexapeptide -1.Oligopeptides -1, oligopeptides -6 and hexapeptide -1 by
2-6 amino acid composition, is easy to be absorbed by skin histology, has and repairs damaged skin, calms down wrinkle, whitening spot-removing and other effects.
As a preferred embodiment, in facial mask essence include essence, the weight proportion of the essence is 0.01%.It is fragrant
Essence can make facial mask essence have unique fragrance, take comfortable experience for user when using facial mask.
The preparation method of Myoporum bontiodes extract includes the following steps：
A) Myoporum bontiodes leaf powder is put into immersion, filtering, ultrafiltration, reduced pressure in solvent by, obtains medicinal extract；Pass through solvent
It impregnates, filter, ultrafiltration and reduced pressure can extract the effective active composition in Myoporum bontiodes leaf powder in medicinal extract.
B) it is adsorbed to saturation through aperture resin column after dissolves the obtained medicinal extract of step a) with ethyl alcohol, is washed with water small
Hole resin column is limpid to efflux, then obtains eluent to colourless with ethanol elution；By the suction of resin column after medicinal extract dissolving
Elution is echoed, the effective active composition in Myoporum bontiodes leaf is further extracted in eluent, while some impurity, pigment being gone
Fall.
C) the obtained eluents of step b) are concentrated under reduced pressure, until remaining liquid is in thick paste, obtain Myoporum bontiodes
Extract.By eluent by being concentrated under reduced pressure to give paste Myoporum bontiodes extract, contain glycoside chemical combination in Myoporum bontiodes extract
Object, mannitol and flavone compound.
As a preferred embodiment, solvent is ethanol solution that volumetric concentration is 60% in step a), and Myoporum bontiodes leaf powder is
The mass ratio of the Myoporum bontiodes leaf powder of 40-60 mesh, Myoporum bontiodes leaf powder and solvent is 1:2~4, Myoporum bontiodes leaf powder, which is put in solvent, to be impregnated
Soaking time be 2-4 days, immersion that Myoporum bontiodes leaf powder is put in solvent, filtration step are repeated 3 times.It is tested by many experiments
Card, in the paste Myoporum bontiodes extract obtained in the above conditions, glucoside compound, mannitol and flavone compound
Recovery rate highest.
A kind of preparation method of the facial mask containing Myoporum bontiodes extract, includes the following steps：
1) Tween-80 is added in Myoporum bontiodes extract and is stirred by, and mixing speed is 300~500 turns/min, then
Add water to be settled to 500mg/mL, obtains solution I.Myoporum bontiodes extract can play the role of whitening, moisturizing to skin.
2) water is added in the reaction kettle equipped with blender, is warming up to 60 DEG C -65 DEG C, is added in the state of being kept stirring
Component A keeps the temperature 15-30 minutes, and mixing speed is 500~800 turns/min, until after being completely dissolved, component B is added and is completely dissolved
Afterwards, 45 DEG C~55 DEG C are cooled to, the solution I that step 1) obtains is added, heat preservation adds component C after 15-30 minutes, obtains solution
Ⅱ.β-glucan, chitosan oligosaccharide, Cer NP in component A have moisturizing, inhibit harmful bacteria growth, anti-aging, repair skin
Barrier and sun-proof effect.Component B have the function of moisturizing, anti-inflammatory, it is anti-aging, make skin emolliency.Component C has moisturizing
Effect.
3) water is added in the reaction kettle with stirring in, is warming up to 80 DEG C~90 DEG C, sequentially adds component D while stirring, stir
It is 800~1000 turns/min to mix speed, until being completely dissolved, obtains solution III.Component D plays the works such as anti-corrosion, thickening, emulsification
With.
4) is slowly added to obtained by step 3) in the state of being kept stirring in the solution II made from step 2)
Solution III, mixing speed be 500~800 turns/min, after keeping the temperature 15~30 minutes after stirring evenly, wait for temperature be down to 30 DEG C~
40 DEG C, component E is added, stirs evenly, mixing speed is that 500~800 turns/min obtains facial mask essence when temperature is down to room temperature
Liquid, degassing are for use.Polypeptide in component E has the effects that anti-aging, smoothing wrinkle, removal red blood silk.
5) impregnates mask substrate 30 minutes in the facial mask essence that step 4) obtains, encapsulation.
As a preferred embodiment, the polypeptide in step 4) is oligopeptides -1, oligopeptides -6 or hexapeptide -1, is being added component E's
Essence is added simultaneously, the weight proportion of essence is 0.01%, and the temperature range of room temperature is 15 DEG C -35 DEG C, and mask substrate is spun lacing
Non-woven fabrics.Mask substrate uses spunlace non-woven cloth, can increase the uptake to facial mask essence.Spunlace non-woven cloth has good
Gas permeability, user using when have better usage experience.
Compared with prior art, the present invention has the advantages that：
1) glucoside compound and Phenylpropanoid Glycosides class of the abundant anti-oxidant and whitening function contained in Myoporum bontiodes extract
Compound, long-time service can make the skin moment keep fit state, reach whitening dispel yellow, moisturizing U.S. face the effect of；
2) contain mannitol in Myoporum bontiodes extract, mannitol can draw a large amount of moisture, no matter in low humidity
Or all there is humectant under high humidity, be the natural moisture preserving raw material of small molecule type, thus contain Myoporum bontiodes extract
Facial mask have effects that deep water supplement；
3) contain flavone compound in Myoporum bontiodes extract, flavone compound is the best natural of inhibition tyrosinase
Raw material, and tyrosinase is the key enzyme of B16 cell, thus the facial mask containing Myoporum bontiodes extract can inhibit melanin to produce
Raw effect, to reach whitening effect；
4) raw material sources are extensive, are easy to get, and preparation method is simple, the economic cost that this facial mask puts goods on the market and other equivalent work(
The facial mask of effect, which is compared, has more superior good economic benefit.
Specific implementation mode
Embodiment 1
The preparation of Myoporum bontiodes extract
A) the Myoporum bontiodes leaf powder that 20kg specifications are 40 mesh is put into the ethanol solution that 40kg volumetric concentrations are 60% and impregnates by
2 days, extracting solution is obtained after filtering, repeats to extract secondary, merging extracting solution progress ultrafiltration, wherein rule are used in ultrafiltration again
Lattice are the ultrafiltration membrane of 5000D, and obtained extracting solution, which is put into Rotary Evaporators, to be concentrated under reduced pressure, and 4kg medicinal extract is obtained；
B) it is adsorbed to saturation through aperture resin column after dissolves the 4kg medicinal extract that step a) is obtained with 2kg ethyl alcohol, is used
It is limpid to efflux to wash aperture resin column, then uses 8kg ethanol elutions to colourless, obtains eluent, wherein ethyl alcohol is anhydrous
Ethyl alcohol；
C) the obtained eluents of step b) are concentrated under reduced pressure, until remaining liquid is in thick paste, obtain Myoporum bontiodes
Extract.
Embodiment 2
The preparation of Myoporum bontiodes extract
A) the Myoporum bontiodes leaf powder that 20kg specifications are 50 mesh is put into the ethanol solution that 60kg volumetric concentrations are 60% and impregnates by
3 days, extracting solution is obtained after filtering, repeats to extract secondary, merging extracting solution progress ultrafiltration, wherein rule are used in ultrafiltration again
Lattice are the ultrafiltration membrane of 5000D, and obtained extracting solution, which is put into Rotary Evaporators, to be concentrated under reduced pressure, and 8kg medicinal extract is obtained；
B) it is adsorbed to saturation through aperture resin column after dissolves the 8kg medicinal extract that step a) is obtained with 4kg ethyl alcohol, is used
It is limpid to efflux to wash aperture resin column, then uses 16kg ethanol elutions to colourless, obtains eluent, wherein ethyl alcohol is nothing
Water-ethanol；
C) the obtained eluents of step b) are concentrated under reduced pressure, until remaining liquid is in thick paste, obtain Myoporum bontiodes
Extract.
Embodiment 3
The preparation of Myoporum bontiodes extract
A) the Myoporum bontiodes leaf powder that 20kg specifications are 60 mesh is put into the ethanol solution that 80kg volumetric concentrations are 60% and impregnates by
4 days, extracting solution is obtained after filtering, repeats to extract secondary, merging extracting solution progress ultrafiltration, wherein rule are used in ultrafiltration again
Lattice are the ultrafiltration membrane of 5000D, and obtained extracting solution, which is put into Rotary Evaporators, to be concentrated under reduced pressure, and 10kg medicinal extract is obtained；
B) it is adsorbed to saturation through aperture resin column after dissolves the 10kg medicinal extract that step a) is obtained with 5kg ethyl alcohol, is used
It is limpid to efflux to wash aperture resin column, then uses 20kg ethanol elutions to colourless, obtains eluent, wherein ethyl alcohol is nothing
Water-ethanol；
C) the obtained eluents of step b) are concentrated under reduced pressure, until remaining liquid is in thick paste, obtain Myoporum bontiodes
Extract.
Embodiment 4
The preparation method of facial mask containing Myoporum bontiodes extract
1) 0.05g Tween-80s are added in 1g Myoporum bontiodes extracts and are stirred by, and mixing speed is 300 turns/min, so
Afterwards plus water is settled to 500mg/mL, obtains solution I.
2) water is added in the reaction kettle equipped with blender, is warming up to 60 DEG C, and component A is added in the state of being kept stirring：
0.02gEDTA disodiums, 0.06g beta glucans, 0.05g chitosan oligosaccharides and 0.15g Cer NPs, keep the temperature 15 minutes, and mixing speed is
500 turns/min, until after being completely dissolved, component B is added：1.2g panthenols, 0.02g hyaluronic acids and 0.15g allantoins, it is completely molten
Xie Hou is cooled to 45 DEG C, and the solution I that step 1) obtains is added, and heat preservation adds component C after 15 minutes：1g glycerine, obtains solution
Ⅱ。
3) water is added in the reaction kettle with stirring in, is warming up to 80 DEG C, sequentially adds component D while stirring：0.18g is poly-
Acrylate crosspolymers -6,1.5g methyl glucose sugar alcohols polyethers -10,0.0015gPEG-40 rilanit specials,
0.2gPEG-12 dimethyl silicone polymers 1016,1g glycine betaines and 0.05g methyl hydroxybenzoates, mixing speed are 800 turns/min, until
It is completely dissolved, obtains solution III.
4) is slowly added to obtained by step 3) in the state of being kept stirring in the solution II made from step 2)
Solution III, mixing speed is 500 turns/min, after keeping the temperature 15 minutes after stirring evenly, waits for that temperature is down to 30 DEG C, component E is added：
The xanthans of 0.25g polypeptides and 0.45g water dissolutions, stirs evenly, and mixing speed is 500 turns/min, waits for that temperature is down to room temperature
When, facial mask essence is obtained, degassing is for use.
5) impregnates mask substrate 30 minutes in the facial mask essence that step 4) obtains, encapsulation.
Embodiment 5
The preparation method of facial mask containing Myoporum bontiodes extract
1) 0.1g Tween-80s are added in 3g Myoporum bontiodes extracts and are stirred by, and mixing speed is 500 turns/min, so
Afterwards plus water is settled to 500mg/mL, obtains solution I.
2) water is added in the reaction kettle equipped with blender, is warming up to 65 DEG C, and component A is added in the state of being kept stirring：
0.06gEDTA disodiums, 0.02g beta glucans, 0.1g chitosan oligosaccharides and 0.1g Cer NPs, keep the temperature 30 minutes, and mixing speed is
800 turns/min, until after being completely dissolved, component B is added：0.4g panthenols, 0.1g hyaluronic acids and 0.05g allantoins, it is completely molten
Xie Hou is cooled to 55 DEG C, and the solution I that step 1) obtains is added, and heat preservation adds component C after 30 minutes：2g glycerine, obtains solution
Ⅱ。
3) water is added in the reaction kettle with stirring in, is warming up to 90 DEG C, sequentially adds component D while stirring：0.06g is poly-
Acrylate crosspolymers -6,2g methyl glucose sugar alcohols polyethers -10,0.001gPEG-40 rilanit specials, 0.1gPEG-12
Dimethyl silicone polymer 1016,2g glycine betaines and 0.15g methyl hydroxybenzoates, mixing speed is 1000 turns/min, until be completely dissolved,
Obtain solution III.
4) is slowly added to obtained by step 3) in the state of being kept stirring in the solution II made from step 2)
Solution III, mixing speed is 800 turns/min, after keeping the temperature 30 minutes after stirring evenly, waits for that temperature is down to 40 DEG C, component E is added：
The xanthans of 0.75g polypeptides and 0.15g water dissolutions, stirs evenly, and mixing speed is 800 turns/min, waits for that temperature is down to room temperature
When, facial mask essence is obtained, degassing is for use.
5) impregnates mask substrate 30 minutes in the facial mask essence that step 4) obtains, encapsulation.
Embodiment 6
The preparation method of facial mask containing Myoporum bontiodes extract
1) 0.07g Tween-80s are added in 2g Myoporum bontiodes extracts and are stirred by, and mixing speed is 400 turns/min, so
Afterwards plus water is settled to 500mg/mL, obtains solution I；
2) water is added in the reaction kettle equipped with blender, is warming up to 62.5 DEG C, and component is added in the state of being kept stirring
A：0.04gEDTA disodiums, 0.03g beta glucans, 0.08g chitosan oligosaccharides and 0.2g Cer NPs keep the temperature 22.5 minutes, stirring speed
Degree is 650 turns/min, until after being completely dissolved, component B is added：1g panthenols, 0.08g hyaluronic acids and 0.1g allantoins, completely
After dissolving, 50 DEG C are cooled to, the solution I that step 1) obtains is added, heat preservation adds component C after 22.5 minutes：1.5g glycerine,
Obtain solution II.
3) water is added in the reaction kettle with stirring in, is warming up to 85 DEG C, sequentially adds component D while stirring：0.1g poly- third
Olefin(e) acid ester cross-linked polymer -6,1g methyl glucose sugar alcohols polyethers -10,0.002gPEG-40 rilanit specials, 0.15g PEG-12
Dimethyl silicone polymer 1016,1.5g glycine betaines and 0.1g methyl hydroxybenzoates, mixing speed is 900 turns/min, until be completely dissolved,
Obtain solution III.
4) is slowly added to obtained by step 3) in the state of being kept stirring in the solution II made from step 2)
Solution III, mixing speed is 650 turns/min, after keeping the temperature 22.5 minutes after stirring evenly, waits for that temperature is down to 35 DEG C, component E is added：
The xanthans of 0.5g polypeptides and 0.3g water dissolutions, stirs evenly, and mixing speed is 650 turns/min, when temperature is down to room temperature,
Facial mask essence is obtained, degassing is for use.
5) impregnates mask substrate 30 minutes in the facial mask essence that step 4) obtains, encapsulation.
Embodiment 6 is to prepare the most preferred embodiment of the facial mask containing Myoporum bontiodes extract, used in following embodiment
The facial mask liquid of the extract containing Myoporum bontiodes is made by embodiment 6.
Embodiment 7
Whitening function evaluation experimental
Experimental procedure：
1. Preparatory work of experiment：The tyrosinase solution of 100U/mL, the l-tyrosine solution and pH of 2.5mmol/L are prepared respectively
=6.8 PBS buffer solution；
Sample solution is prepared：By the facial mask liquid containing Myoporum bontiodes extract, the facial mask liquid of blank and commercially available white-skinned face function face
Film liquid is configured to the sample solution that mass fraction is 1.0% with the PBS buffer solution of pH=6.8 respectively.
2, experimental method
According to number is added to shown in table 1 it is successively A by l-tyrosine, sample solution, PBS buffer solution1、A2、B1、B2Group is each
Mixing in test tube；Test tube is put into water-bath 10-15 minutes in 37 DEG C of thermostat water baths；Tyrosinase is sequentially added into A1And B1Group
It in each pipe, shakes up, accurate timing, reacts 15 minutes and stop.
The contact plate on 96 orifice plates successively again, measures its absorbance with microplate reader and calculates inhibiting rate.
Inhibiting rate calculation formula is：
Tyrosinase inhibition rate (%)=(A1-A2)-(B1-B2)/A1-A2× 100%
In formula, A1There is enzyme system absorbance for blank model；A2It is blank model without enzyme system absorbance； B1For sample sets
There is enzyme system absorbance；B2It is sample sets without enzyme system absorbance.
Table 1
| Reaction group | V(l-tyrosine)(mL) | V(sample solution)(mL) | V(PBS)(mL) | V(tyrosinase)(mL) |
| A1 | 2 | 0 | 4 | 1 |
| A2 | 2 | 0 | 5 | 0 |
| B1 | 2 | 2 | 2 | 1 |
| B2 | 2 | 2 | 3 | 0 |
It the results are shown in Table 2：
Table 2
| Test specimens | Inhibiting rate (%) |
| Facial mask liquid containing Myoporum bontiodes extract | 57.10±0.16 |
| Blank facial mask liquid | 15.36±0.03 |
| Commercially available white-skinned face function facial mask liquid | 24.18±0.56 |
As shown in Table 2, the facial mask liquid containing Myoporum bontiodes extract is far above blank facial mask liquid to the inhibiting rate of tyrosinase
With commercially available white-skinned face function facial mask liquid.It follows that melanin can be inhibited to be formed using the facial mask containing Myoporum bontiodes extract, to
Reach good whitening effect.
Embodiment 8
Anti-oxidation function evaluation experimental
1, DPPH free radical scavenging abilities assay method
The preparation of DPPH storing solutions：DPPH (1,1- diphenyl -2- trinitrophenyl-hydrazines) reagent 3.5mg accurately is weighed, with nothing
Water-ethanol dissolves, and is quantitatively transferred in 10mL volumetric flasks, is settled to scale with absolute ethyl alcohol, takes in 2mL to 100mL volumetric flasks,
Shake up to obtain a concentration of 0.0178mmol/L DPPH storing solutions, be placed in refrigerator refrigerate it is spare.
The preparation of sample solution：Accurately weighing 500mg contains the facial mask liquid of Myoporum bontiodes extract, 500mg blank facial mask liquids
With the commercially available anti-oxidation efficacy facial mask liquids of 500mg, and quantitatively it is transferred in 50mL volumetric flasks, it is quantitative to scale with absolute ethyl alcohol, it takes
In 10mL to 100mL volumetric flasks, a concentration of 0.0233mmol/L sample solutions are shaken up to obtain.
The measurement of DPPH free radical scavenging activities：Sequentially added in 10mL colorimetric cylinders 4.0mL DPPH storing solutions and
4.0mL0.0233mmol/L sample solutions add absolute ethyl alcohol to scale, and mixing uses 1cm cuvettes in 517nm wavelength immediately
Place surveys light absorption value (A), and light absorption value is denoted as Ai, then light absorption value is surveyed after greenhouse is kept in dark place 30 minutes, it is denoted as Aj, check experiment is
Only plus the ethanol solution of DPPH storing solutions, light absorption value are denoted as Ac.It is calculated as follows：
DPPH free radical scavenging activities (%)=[1- (Ai-Aj)/Ac] × 100%；
2, ABTS free radical scavenging abilities assay method
The preparation of ABTS working solutions：The 140mmol/L potassium peroxydisulfates of the 7mmol/L ABTS of 5mL and 88 μ L are mixed equal
It is even, room temperature (25 DEG C), be protected from light under conditions of stand overnight 12h, form ABTS free radical storing solutions, 10mmol/ used before use
The PBS buffer solution of L pH=7.4 is diluted to ABTS working solutions, and making it, the absorbance under 734nm wavelength is 0.70 at room temperature
±0.02。
The preparation of sample solution：By the facial mask liquid containing Myoporum bontiodes extract, blank facial mask liquid and commercially available anti-oxidation efficacy
Facial mask liquid is configured to the sample solution that mass fraction is 1.0% with the PBS buffer solution of PH=7.4 respectively.
It is loaded by the following method, and each sample does three repetitions：
ASample：+ 200 μ L ABTS working solutions of 10 μ L samples solution；
ASample controls：The PBS buffer solution of+200 μ L PH=7.4 of 10 μ L samples solution；
ABuffer control：The PBS buffer solution of+200 μ L PH=7.4 of 10 μ L water；
AABTS is compareed：+ 200 μ L ABTS working solutions of 10 μ L water；
10s is mixed, absorbance value is read in 405nm after standing 6 minutes.The clearance rate of ABTS is calculated as follows：
ABTS free radical scavenging activities (%)=[1- (ASample-ASample controls)/(AABTS is compareed-ABuffer control)] × 100%.
It the results are shown in Table 3：
Table 3
| Test specimens | DPPH | ABTS |
| Facial mask liquid containing Myoporum bontiodes extract | 31.26±0.20 | 18.33±0.62 |
| Blank facial mask liquid | 5.65±0.18 | 1.88±0.11 |
| Commercially available anti-oxidation efficacy facial mask liquid | 19.76±0.65 | 7.72±0.16 |
The antioxidant activity that can be seen that the facial mask liquid containing Myoporum bontiodes extract from the data of table 3 is better than blank face
Film liquid and commercially available anti-oxidation efficacy facial mask liquid.
Embodiment 9
Comprehensive performance evaluation is tested
Experimental procedure：Experiment is divided into three groups, the facial mask, blank facial mask respectively containing Myoporum bontiodes extract and commercially available whitening
Effect facial mask.
The female volunteers of 100 dark yellow dryings of skin are collected, all triers are that 25-35 years old or more voluntary participation is surveyed
The healthy women of examination.Three groups of triers distribute the facial mask containing Myoporum bontiodes extract, blank facial mask and commercially available white-skinned face function respectively
Facial mask 30, using once, the trial employment period needs trier's observation using result and records within two days.Usage time 60 days.
It the results are shown in Table 4：
Table 4
As known from Table 4：The whitening of facial mask containing Myoporum bontiodes extract, blank facial mask and commercially available facial mask is dispelled the expiring of yellow effect
Meaning degree is respectively that the satisfaction of the moistness effect of 95%, 18% and 49%, and three kinds of facial masks is respectively 92%, 85% and
87%, above the experimental results showed that there is Myoporum bontiodes extract very strong whitening to dispel yellow function and moist function, to also table
Bright Myoporum bontiodes extract has preferable whitening function as facial mask essence, and is used for a long time and can moisturize the skin, and keeps skin rich
It is flexible.
Blank facial mask described in embodiment 7 to embodiment 9 refers to other compositions with proportioning as embodiment 6, but not
Extract containing Myoporum bontiodes.
What has been described above is only a preferred embodiment of the present invention, it is noted that for those of ordinary skill in the art
For, without departing from the concept of the premise of the invention, various modifications and improvements can be made, these belong to the present invention
Protection domain.
Claims (10)
1. a kind of facial mask containing Myoporum bontiodes extract, it is characterised in that：Including mask substrate and contain Myoporum bontiodes extract
Facial mask essence, the facial mask essence are made of component A, B, C, D, E, Myoporum bontiodes extract, Tween-80 and water.
2. a kind of facial mask containing Myoporum bontiodes extract according to claim 1, it is characterised in that：The component A by
EDETATE SODIUM, beta glucan, chitosan oligosaccharide and Cer NP composition；The component B is made of panthenol, hyaluronic acid and allantoin；
The component C is glycerine；The component D is by polyacrylate cross-linked polymer -6, methyl glucose sugar alcohol polyethers -10, PEG-40
Rilanit special, PEG-12 dimethyl silicone polymers 1016, glycine betaine and methyl hydroxybenzoate composition；The component E is by polypeptide and Huang
Virgin rubber forms.
3. a kind of facial mask containing Myoporum bontiodes extract according to claim 1, it is characterised in that：The facial mask essence
It is made of following raw material and weight proportion：
Component A：EDETATE SODIUM 0.02~0.06%, beta glucan 0.02~0.06%, chitosan oligosaccharide 0.05~0.1% and neural acyl
Amine 3 0.1~0.2%；
Component B：Panthenol 0.4~1.2%, hyaluronic acid 0.02~0.1% and allantoin 0.05~0.15%；
Component C：Glycerine 1~2%；
Component D：Polyacrylate cross-linked polymer -6 0.06~0.18%, methyl glucose sugar alcohol polyethers -10 1~2%, PEG-
40 rilanit specials 0.001~0.002%, PEG-12 dimethyl silicone polymers 1,016 0.1~0.2%, 1~2% and of glycine betaine
Methyl hydroxybenzoate 0.05~0.15%；
Component E：Polypeptide 0.25~0.75% and xanthans 0.15~0.45%；
Myoporum bontiodes extract 1~3%, Tween-80 0.05~0.1% and water surplus.
4. a kind of facial mask containing Myoporum bontiodes extract according to claim 3, it is characterised in that：The facial mask essence
It is made of following raw material and weight proportion：
Component A：EDETATE SODIUM 0.04%, beta glucan 0.03%, chitosan oligosaccharide 0.08% and Cer NP 0.2%；
Component B：Panthenol 1%, hyaluronic acid 0.08% and allantoin 0.1%；
Component C：Glycerine 1.5%；
Component D：Polyacrylate cross-linked polymer -6 0.1%, methyl glucose sugar alcohol polyethers -10 1%, PEG-40 hydrogenated castors
Oil 0.002%, PEG-12 dimethyl silicone polymers 1,016 0.15%, glycine betaine 1.5% and methyl hydroxybenzoate 0.1%；
Component E：Polypeptide 0.5% and xanthans 0.3%；
Myoporum bontiodes extract 2%, Tween-80 0.07% and water surplus.
5. a kind of facial mask containing Myoporum bontiodes extract according to claim 4, it is characterised in that：The polypeptide is widow
Peptide -1, oligopeptides -6 or hexapeptide -1.
6. a kind of facial mask containing Myoporum bontiodes extract according to claim 5, it is characterised in that：The facial mask essence
In include essence, the weight proportion of the essence is 0.01%.
7. according to a kind of any facial masks containing Myoporum bontiodes extract of claim 1-6, it is characterised in that：The hardship sill
The preparation method of blue extract includes the following steps：
A) Myoporum bontiodes leaf powder is put into immersion, filtering, ultrafiltration, reduced pressure in solvent by, obtains medicinal extract；
B) it is adsorbed to saturation through aperture resin column after dissolves the obtained medicinal extract of step a) with ethyl alcohol, aperture tree is washed with water
Fat column is limpid to efflux, then obtains eluent to colourless with ethanol elution；
C) the obtained eluents of step b) are concentrated under reduced pressure, until remaining liquid is in thick paste, obtain Myoporum bontiodes extraction
Object.
8. a kind of preparation method of Myoporum bontiodes extract according to claim 7, it is characterised in that：It is molten in the step a)
Agent is the ethanol solution that volumetric concentration is 60%, and the Myoporum bontiodes leaf powder is the Myoporum bontiodes leaf powder of 40-60 mesh, the Myoporum bontiodes leaf
The mass ratio of powder and solvent is 1:2~4, it is 2-4 days that the Myoporum bontiodes leaf powder, which is put in the soaking time impregnated in solvent, the hardship
Immersion that sill indigo plant leaf powder is put in solvent, filtration step are repeated 3 times.
9. a kind of preparation method of facial mask containing Myoporum bontiodes extract according to claim 8, it is characterised in that：Including
Following steps：
1) Tween-80 is added in Myoporum bontiodes extract and is stirred by, and mixing speed is 300~500 turns/min, then adds water
It is settled to 500mg/mL, obtains solution I；
2) water is added in the reaction kettle equipped with blender, is warming up to 60 DEG C -65 DEG C, and component is added in the state of being kept stirring
A keeps the temperature 15-30 minutes, and mixing speed is 500~800 turns/min, until after being completely dissolved, after addition component B is completely dissolved,
45 DEG C~55 DEG C are cooled to, the solution I that step 1) obtains is added, heat preservation adds component C after 15-30 minutes, obtains solution II；
3) water is added in the reaction kettle with stirring in, is warming up to 80 DEG C~90 DEG C, sequentially adds component D, stirring speed while stirring
Degree is 800~1000 turns/min, until being completely dissolved, obtains solution III；
4) is slowly added to the solution made from step 3) in the state of being kept stirring in the solution II made from step 2)
III, mixing speed is 500~800 turns/min, after keeping the temperature 15~30 minutes after stirring evenly, waits for that temperature is down to 30 DEG C~40 DEG C,
Component E is added, stirs evenly, mixing speed is that 500~800 turns/min obtains facial mask essence when temperature is down to room temperature, is taken off
Gas is for use；
5) impregnates mask substrate 30 minutes in the facial mask essence that step 4) obtains, encapsulation.
10. a kind of preparation method of facial mask containing Myoporum bontiodes extract according to claim 9, it is characterised in that：Institute
The polypeptide stated in step 4) is oligopeptides -1, oligopeptides -6 or hexapeptide -1, and essence is added while component E is added, the essence
Weight proportion is 0.01%, and the temperature range of the room temperature is 15 DEG C -35 DEG C, and the mask substrate is spunlace non-woven cloth.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810607370.XA CN108619020B (en) | 2018-06-13 | 2018-06-13 | A facial mask containing herba Ixeritis Sonchifoliae extract and its preparation method |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810607370.XA CN108619020B (en) | 2018-06-13 | 2018-06-13 | A facial mask containing herba Ixeritis Sonchifoliae extract and its preparation method |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN108619020A true CN108619020A (en) | 2018-10-09 |
| CN108619020B CN108619020B (en) | 2022-02-01 |
Family
ID=63691352
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201810607370.XA Active CN108619020B (en) | 2018-06-13 | 2018-06-13 | A facial mask containing herba Ixeritis Sonchifoliae extract and its preparation method |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN108619020B (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109674715A (en) * | 2019-03-07 | 2019-04-26 | 张家界中天生物科技有限公司 | A kind of moisturizing whitening anti-aging facial mask |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6327425A (en) * | 1986-07-21 | 1988-02-05 | Kao Corp | Remedy for acne vulgaris |
| JP2009197035A (en) * | 2009-06-11 | 2009-09-03 | Tsujido Chemical Corp | External preparation for skin |
| CN101897347A (en) * | 2010-07-09 | 2010-12-01 | 华南农业大学 | Plant-based bacteriostat, preparation method thereof and application thereof |
| CN106214552A (en) * | 2016-08-24 | 2016-12-14 | 宁波枫叶杰科生物技术有限公司 | A kind of facial film containing plant extract |
| CN107362084A (en) * | 2017-07-28 | 2017-11-21 | 张家界久瑞健康产业发展有限公司 | A kind of facial mask containing Chinese sumac leaf extract and preparation method thereof |
-
2018
- 2018-06-13 CN CN201810607370.XA patent/CN108619020B/en active Active
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6327425A (en) * | 1986-07-21 | 1988-02-05 | Kao Corp | Remedy for acne vulgaris |
| JP2009197035A (en) * | 2009-06-11 | 2009-09-03 | Tsujido Chemical Corp | External preparation for skin |
| CN101897347A (en) * | 2010-07-09 | 2010-12-01 | 华南农业大学 | Plant-based bacteriostat, preparation method thereof and application thereof |
| CN106214552A (en) * | 2016-08-24 | 2016-12-14 | 宁波枫叶杰科生物技术有限公司 | A kind of facial film containing plant extract |
| CN107362084A (en) * | 2017-07-28 | 2017-11-21 | 张家界久瑞健康产业发展有限公司 | A kind of facial mask containing Chinese sumac leaf extract and preparation method thereof |
Non-Patent Citations (5)
| Title |
|---|
| 叶慧娟等: "苦槛蓝叶的化学成分及其抑菌活性研究", 《热带亚热带植物学报》 * |
| 李结雯等: "苦槛蓝总黄酮含量测定及其提取工艺研究", 《广东化工》 * |
| 王昌涛等: "《化妆品植物添加剂的开发与应用》", 30 April 2013, 中国轻工业出版社 * |
| 裘炳毅等: "《现代化妆品科学与技术》", 31 March 2016, 中国轻工业出版社 * |
| 贺近恪等: "《林产化学工业全书》", 28 February 2001, 中国林业出版社 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109674715A (en) * | 2019-03-07 | 2019-04-26 | 张家界中天生物科技有限公司 | A kind of moisturizing whitening anti-aging facial mask |
Also Published As
| Publication number | Publication date |
|---|---|
| CN108619020B (en) | 2022-02-01 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN102525855B (en) | Preparation process for peach gum aqueous solution and prepared skin care products | |
| CN107362084A (en) | A kind of facial mask containing Chinese sumac leaf extract and preparation method thereof | |
| CN105147550B (en) | A kind of whitening moisturizing face masque liquid containing nostoc sphaeroids kutz extractive and preparation method thereof | |
| CN102940597B (en) | Natural compound botanical antioxidant, as well as preparation method and application thereof in cosmetics | |
| CN106491460B (en) | A kind of eye essence and preparation method thereof | |
| CN107929190A (en) | One kind is releived antiallergic facial mask and preparation method | |
| CN110192996A (en) | A kind of viola mandshurica moisturizer and preparation method thereof and the moisturizing moisturizing sleep mask containing the moisturizer | |
| CN109535269A (en) | A kind of preparation process and its application of dendrobium nobile micromolecular polysaccharide extracting solution | |
| CN107714631A (en) | A kind of collagen peptide facial mask liquid and preparation method thereof | |
| CN106619379B (en) | A kind of composition of the product containing plant fermentation and its preparation method and application | |
| CN108653137B (en) | Composition and application thereof in preparation of beauty cosmetics | |
| CN110037958A (en) | A kind of pox-eliminating whitening moisture saver mask of the ingredient containing trollflower and preparation method thereof | |
| CN108553364A (en) | A kind of skin replenishing water and preserving moisture composition with smooth skin and its application in skin care item | |
| CN108619020A (en) | A kind of facial mask and preparation method thereof containing Myoporum bontiodes extract | |
| CN115300437B (en) | Moisturizing and anti-aging skin care composition and preparation method and application thereof | |
| CN112656700A (en) | Cosmetic composition containing industrial hemp extract and preparation method thereof | |
| CN107714632B (en) | Black tea fungus fermentation mask liquid and preparation method thereof | |
| CN110227050A (en) | A kind of anti-aging maintenance sustained release Essence and the anti-aging Face-protecting mask using its preparation | |
| CN110237002A (en) | A kind of moisture saver mask and preparation method thereof containing fragrant lotus extract | |
| CN110236974A (en) | A kind of toner and preparation method thereof containing glycine betaine salicylic acid ionic liquid | |
| CN115137675A (en) | Compound plant extract with moisturizing effect and application thereof | |
| CN108420758A (en) | A kind of biological enzyme processing and corrosion-resistant honeysuckle flowers plant extraction liquid and preparation method thereof | |
| CN108186440A (en) | Can antibiotic skin-care Chinese medicinal plant shower cream and its preparation method and application | |
| CN110840793B (en) | Fibroin mask liquid and preparation method thereof | |
| CN107550810B (en) | Traditional Chinese medicine composition and preparation method and application thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| GR01 | Patent grant | ||
| GR01 | Patent grant |