CN108567913A - A kind of drug and preparation method thereof for treating diabetes - Google Patents
A kind of drug and preparation method thereof for treating diabetes Download PDFInfo
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- A61K36/185—Magnoliopsida (dicotyledons)
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Abstract
The invention discloses a kind of drug and preparation method thereof for treating diabetes, each parts by weight of raw materials is as follows:15 30 parts of Radix Rehmanniae, 15 25 parts of dogwood fruit, 10 15 parts of Radix Ophiopogonis, 15 20 parts of the stem of noble dendrobium, 50 80 parts of Chinese yam, 15 25 parts of Radix Astragali, 20 30 parts of rhizoma anemarrhenae, 8 15 parts of the membrane of a chicken's gizzard, 10 15 parts of pueraria lobata, 15 30 parts of root of Chinese trichosanthes, 10 15 parts of Herba Epimedii, 10 15 parts of Radix Codonopsis, 10 15 parts of Rhizoma Atractylodis Macrocephalae, 8 10 parts of the root bark of tree peony, 8 10 parts of Schisandra chinensis, 15 25 parts of radix scrophulariae.Preparation method is to crush each bulk pharmaceutical chemicals, crosses 100 150 mesh sieve, mixing;By medicinal powder:The weight ratio of honey is 1:Medicinal powder is added to by 1 ratio to be heated in 80 100 DEG C of honey, stirs evenly and honey ointment is made, and room temperature cools down to get honeyed bolus.The present invention drug cure mainly type of deficiency of both QI and YIN, type of hyperactivity of fire caused by deficiency of YIN, yin-yang deficiency type, Qi deficiency blood stasis type, it is scorching enter blood group diabetes, have the characteristics that rapid-action, good effect, safe without toxic side effect.Clinical 120 patients use, total effective rate 95%.
Description
Technical field
The invention belongs to the field of Chinese medicines, and in particular to a kind of drug for treating diabetes also relates to the treatment glycosuria
The preparation method of the drug of disease.
Background technology
Diabetes(LE)It is a kind of typical autoimmune connective tissue disease, is more common in 15~40 years old women.Diabetes
It is a kind of disease spectrality disease, plate-like diabetes can be divided into(DLE), Subacute Cutaneous patients with type Ⅰ DM(SCLE), systemic glycosuria
Disease(SLE), deep-seated diabetes(LEP), neonatal diabetes mellitus(NLE), Hypoglycemic agents(DIL)Etc. hypotypes.Diabetes are
One of several big diseases of human health are seriously endangered, according to the statistics made by the departments concerned, there are about 100,000,000 or more diabetes patients in the whole world, and
There are about more than 4,000 ten thousand in China.Its formation and the daily rule of life of people, diet, environment, mood and all kinds of chemical substances
Damage has close relationship.Its basic pathology physiology is internal insulin with respect to hyposecretion, so as to cause carbohydrate,
Fat, protein, water and metabolic disturbance of electrolyte.However diabetes are not just for some age bracket, it is to each
Age bracket can have an impact, it has also become seriously threaten the public health problem in human health and service life.Due to hobby drink and
Sweet fertilizer diet or ferritic kidney deficiency, to form the deficiency of Yin and scorching pathological change, the two reciprocal causation, disappear bright lung stomach body fluid and
The moon essence of kidney.Disturbance of carbohydrate metabolism caused by hypoinsulinism.It is excessively high and glucose in urine occur characterized by blood glucose.
Currently, clinical treatment diabetes, select diabetes treatment by western medicine, although can be generated to the state of an illness certain or preferable
Control action, but mostly side effect is big, hepatic and renal function may be caused to damage, and drug dependence is strong so that patient needs lifelong
Medication.From Chinese medicine angle, mirror belongs to the sick scope of motherland's medicine " quenching one's thirst " to diabetes.Pathology is mainly deficiency of Yin scorching, and cloudy
Empty emphasis belongs to empty in kidney, scorching essence.So treatment is when to nourish kidney yin, based on clearing heat and moistening dryness.Chinese medicine treatment is bad anti-
Answer it is small, currently on the market used in Chinese medicine also type is various, but effect is irregular, I is unequal to ideal.
Invention content
The purpose of the present invention is to provide the drugs of a kind of rapid-action, good effect, the treatment diabetes having no toxic side effect.
Another object of the present invention is to provide the preparation methods of the drug of the treatment diabetes.
A kind of drug for treating diabetes of the present invention, by weight, including following raw material:
15-30 parts of Radix Rehmanniae, 15-25 parts of dogwood fruit, Radix Ophiopogonis 10-15 part, 15-20 parts of the stem of noble dendrobium, 50-80 parts of Chinese yam, Radix Astragali 15-25
Part, 20-30 parts of rhizoma anemarrhenae, 8-15 parts of the membrane of a chicken's gizzard, 10-15 parts of pueraria lobata, 15-30 parts of root of Chinese trichosanthes, 10-15 parts of Herba Epimedii, Radix Codonopsis 10-15
Part, 10-15 parts of Rhizoma Atractylodis Macrocephalae, 8-10 parts of the root bark of tree peony, 8-10 parts of Schisandra chinensis, 15-25 parts of radix scrophulariae.
A kind of above-mentioned drug for treating diabetes, by weight, preferably following raw material:
30 parts of Radix Rehmanniae, 25 parts of dogwood fruit, 15 parts of Radix Ophiopogonis, 15 parts of the stem of noble dendrobium, 80 parts of Chinese yam, 20 parts of Radix Astragali, 25 parts of rhizoma anemarrhenae, the membrane of a chicken's gizzard 10
Part, 15 parts of pueraria lobata, 25 parts of root of Chinese trichosanthes, 10 parts of Herba Epimedii, 15 parts of Radix Codonopsis, 15 parts of Rhizoma Atractylodis Macrocephalae, 10 parts of the root bark of tree peony, 10 parts of Schisandra chinensis, radix scrophulariae
25 parts.
A kind of preparation method of drug for treating diabetes of the present invention, includes the following steps:
(1)Bulk pharmaceutical chemicals are screened, are cleaned, drying takes each bulk pharmaceutical chemicals by weight;
(2)Each bulk pharmaceutical chemicals are crushed, 100-150 mesh sieve, mixing are crossed;
(3)By medicinal powder:The weight ratio of honey is 1:Medicinal powder is added in the honey for being heated to 80-100 DEG C by 1 ratio, stirring
Honey ointment is uniformly made, room temperature cools down to get honeyed bolus.
Compared with prior art, the present invention there is apparent advantageous effect, as can be known from the above technical solutions:The present invention selects life
Ground, dogwood fruit, Radix Ophiopogonis, the stem of noble dendrobium, Chinese yam, Radix Astragali, rhizoma anemarrhenae, the membrane of a chicken's gizzard, pueraria lobata, root of Chinese trichosanthes, Herba Epimedii, Radix Codonopsis, Rhizoma Atractylodis Macrocephalae, the root bark of tree peony,
Schisandra chinensis, radix scrophulariae are raw material.
Herbal pharmacology of the present invention is as follows:
Radix Rehmanniae:Nature and flavor sweetness and bitterness is cold, and clearing heat and cooling blood, cardiac stimulant diuresis, reduces blood glucose and promotes blood clotting Yin-nourishing and body fluid promoting.
Dogwood fruit:Tepor that nature and flavor is sour and astringent, tonifying kidney and benefiting sperm, puckery essence, hidroschesis, tonifying liver.
Radix Ophiopogonis:Nature and flavor is sweet, and slight bitter is slightly cold, Yin nourishing and lung moistening, reinforcing stomach reg fluid, relieving restlessness that clears away heart-fire.
The stem of noble dendrobium:Nature and flavor is sweet flat, replenishing the vital essence and removing heat, nourishing the stomach to improve the production of body fluid.
Chinese yam:Nature and flavor is sweet flat, replenish qi to invigorate the spleen, beneficial lung yin-nourishing, kidney tonifying relieving leukorrhea by astringents.
Radix Astragali:The sweet tepors of nature and flavor, Gu table arrest sweating, myogenic, tonifying Qi, cardiac stimulant diuresis.
Rhizoma anemarrhenae:Nature and flavor bitter colds, enriching yin, are quenched the thirst at relieving restlessness.
The membrane of a chicken's gizzard:Nature and flavor is sweet flat, digestion-promoting spleen-invigorating, antidiarrheal.
Pueraria lobata:Nature and flavor Gan Xinping, dispelling wind and heat, expelling pathogenic factors from muscles and skin promoting eruption.
Root of Chinese trichosanthes:Nature and flavor is sweet, and slight bitter is slightly cold, clearing heat and promoting fluid, clearing away the lungheat and moisturizing, detumescence and apocenosis.
Herba Epimedii:Nature and flavor Xin Ganwen, warming and invigorating kidney Yang, strengthening the bones and muscles, wind-damp dispelling.
Radix Codonopsis:The sweet tepors of nature and flavor, nourishes blood and promotes the production of body fluid are quenched the thirst.
Rhizoma Atractylodis Macrocephalae:Nature and flavor bitter sweet temperature, five viscera settling, replenish qi to invigorate the spleen, eliminate dampness and have diuretic effect, strengthening exterior and reducing sweat, tonifying Qi tocolysis, defaecation.
The root bark of tree peony:Nature and flavor is arduous cold, promoting blood circulation and removing blood stasis, clearing heat and cooling blood.
Schisandra chinensis:Nature and flavor acid is salty and bitter, and tonifying kidney and benefiting sperm astringes the lung, promotes the production of body fluid, arrest sweating, antidiarrheal.
Radix scrophulariae:Nature and flavor hardships are salty-cold, and nourishing yin and lessening fire, removing toxic substances of promoting the production of body fluid, decompression are hypoglycemic.
The effect of nourishing kidney yin, clearing heat and moistening dryness, quench one's thirst of promoting the production of body fluid is played by the synergistic effect of each drug.Cure mainly deficiency of both qi and yin
Type, type of hyperactivity of fire caused by deficiency of YIN, yin-yang deficiency type, Qi deficiency blood stasis type, it is scorching enter blood group diabetes, drug of the invention have it is rapid-action,
The characteristics of good effect, safe without toxic side effect.Clinical 120 patients use, total effective rate 95%.
Specific implementation mode
Carry out the advantageous effect of the present invention is further explained the drug below by way of test example.
Test example:The clinical observation of drug of the present invention
1, clinical data:
All cases 120, wherein max age 62 years old, minimal ages 40 years old, man 58, female 62.
2, diagnostic criteria:
《Disease of tcm Standardization of diagnosis and curative effect》.
3, therapy:
Drug obtained by the oral embodiment of the present invention daily three to four times, 10 grams every time, is given up alcohol, cold, the pungent food of acid during medication
Object should not separately take other nourishing drugs.Half a month is as a treatment course;The 1-2 courses for the treatment of, clinically various symptoms will obviously subtract
Gently;The 4-6 courses for the treatment of can control normal.
4, criterion of therapeutical effect:
It is effective:Symptom disappears;
Effectively:Symptom is relieved;
In vain:Symptom is not improved.
5, treatment results:
120 patients' use drugs of the present invention, effective 102, effective 12, invalid 6, obvious effective rate 85%, total effective rate 95%.
6, model case:
(1) Wu:Female, 52 years old.Because more drink diuresis are eaten more, body is become thin, soreness of waist and knee, feverishness in palms and soles, chilly limb within 2012
Cold, glucose in urine (180), 190 milligrams of % of fasting blood-glucose come to see a doctor.After taking 4 course for the treatment of of drug of the present invention, symptom, sign disappear, and look into
Urine is negative, 100 milligrams of % of fasting blood-glucose.Two course for the treatment of of following the service afterwards, recurrence that so far there are no.
(2) Huang:Man, 45 years old.Gluttony can be eaten more than 1 year within 2012.Half a month is dizzy weak, hospital's inspection discovery glucose in urine,
Blood glucose is high, polydipsia, and urine is more.After taking two course for the treatment of of drug of the present invention, " three disappear " symptom disappears substantially, and glucose in urine is negative, empty
Abdomen blood glucose 81mm%;After taking two courses for the treatment of again, symptom of quenching one's thirst is not sent out always, and multiple checks blood glucose glucoses in urine are normal.
(3) Chen:Man, 41 years old.Morbidity's half a year in 2013, thirst with desire to drink, drink do not quench one's thirst, daily drink amount up to 20 jin with
On, rapid digestion of food and polyorexia, nearly 1 kilogram of daily staple food amount, sugared glucoses in urine of having a blood test are high.Two course for the treatment of of drug of the present invention is taken, all diseases mitigate.
Four course for the treatment of of following the service afterwards, three eliminating mass shapes disappear, and glucose in urine is turned out cloudy, and glycemic control is 6.8 or so.Follow-up after 1 year, patient experiences stable disease,
No abnormality seen.
The preparation method of this drug is illustrated by following embodiment.
Embodiment 1
A kind of preparation method of drug that treating diabetes, includes the following steps:
(1)Bulk pharmaceutical chemicals are screened, are cleaned, drying weighs Radix Rehmanniae 15g, dogwood fruit 25g, Radix Ophiopogonis 10g, stem of noble dendrobium 20g, Chinese yam 50g, Huang
Stilbene 25g, rhizoma anemarrhenae 20g, the membrane of a chicken's gizzard 15g, pueraria lobata 10g, root of Chinese trichosanthes 30g, Herba Epimedii 10g, Radix Codonopsis 15g, Rhizoma Atractylodis Macrocephalae 10g, root bark of tree peony 10g,
Schisandra chinensis 8g, radix scrophulariae 25g;
(2)Each bulk pharmaceutical chemicals are crushed, are sieved with 100 mesh sieve, mixing;
(3)By medicinal powder:The weight ratio of honey is 1:Medicinal powder is added to by 1 ratio to be heated in 100 DEG C of honey, is stirred evenly
Honey ointment is made, room temperature cools down to get honeyed bolus.
Embodiment 2
A kind of preparation method of drug that treating diabetes, includes the following steps:
(1)Bulk pharmaceutical chemicals are screened, are cleaned, drying weighs Radix Rehmanniae 15g, dogwood fruit 25g, Radix Ophiopogonis 15g, stem of noble dendrobium 15g, Chinese yam 80g, Huang
Stilbene 20g, rhizoma anemarrhenae 25g, the membrane of a chicken's gizzard 10g, pueraria lobata 15g, root of Chinese trichosanthes 25g, Herba Epimedii 10g, Radix Codonopsis 15g, Rhizoma Atractylodis Macrocephalae 15g, root bark of tree peony 10g,
Schisandra chinensis 10g, radix scrophulariae 25g;
(2)Each bulk pharmaceutical chemicals are crushed, 120 mesh sieve, mixing are crossed;
(3)By medicinal powder:The weight ratio of honey is 1:Medicinal powder is added to by 1 ratio to be heated in 90 DEG C of honey, is stirred evenly
Honey ointment is made, room temperature cools down to get honeyed bolus.
Embodiment 3
A kind of preparation method of drug that treating diabetes, includes the following steps:
(1)Bulk pharmaceutical chemicals are screened, are cleaned, drying weighs Radix Rehmanniae 20g, dogwood fruit 20g, Radix Ophiopogonis 13g, stem of noble dendrobium 18g, Chinese yam 65g, Huang
Stilbene 20g, rhizoma anemarrhenae 25g, the membrane of a chicken's gizzard 11g, pueraria lobata 12g, root of Chinese trichosanthes 22g, Herba Epimedii 12g, Radix Codonopsis 13g, Rhizoma Atractylodis Macrocephalae 13g, root bark of tree peony 9g, five
Taste 9g, radix scrophulariae 20g;
(2)Each bulk pharmaceutical chemicals are crushed, 120 mesh sieve, mixing are crossed;
(3)By medicinal powder:The weight ratio of honey is 1:Medicinal powder is added to by 1 ratio to be heated in 90 DEG C of honey, is stirred evenly
Honey ointment is made, room temperature cools down to get honeyed bolus.
Embodiment 4
A kind of preparation method of drug that treating diabetes, includes the following steps:
(1)Bulk pharmaceutical chemicals are screened, are cleaned, drying weighs Radix Rehmanniae 30g, dogwood fruit 15g, Radix Ophiopogonis 15g, stem of noble dendrobium 15g, Chinese yam 80g, Huang
Stilbene 15g, rhizoma anemarrhenae 30g, the membrane of a chicken's gizzard 8g, pueraria lobata 15g, root of Chinese trichosanthes 15g, Herba Epimedii 15g, Radix Codonopsis 10g, Rhizoma Atractylodis Macrocephalae 15g, root bark of tree peony 8g, five
Taste 10g, radix scrophulariae 15g;
(2)Each bulk pharmaceutical chemicals are crushed, 150 mesh sieve, mixing are crossed;
(3)By medicinal powder:The weight ratio of honey is 1:Medicinal powder is added to by 1 ratio to be heated in 80 DEG C of honey, is stirred evenly
Honey ointment is made, room temperature cools down to get honeyed bolus.
The above described is only a preferred embodiment of the present invention, being not intended to limit the present invention in any form, Ren Hewei
Be detached from technical solution of the present invention content, according to the technical essence of the invention to made by above example it is any it is simple modification, etc.
With variation and modification, in the range of still falling within technical solution of the present invention.
Claims (3)
1. a kind of drug for treating diabetes, by weight, including following raw material:
15-30 parts of Radix Rehmanniae, 15-25 parts of dogwood fruit, Radix Ophiopogonis 10-15 part, 15-20 parts of the stem of noble dendrobium, 50-80 parts of Chinese yam, Radix Astragali 15-25
Part, 20-30 parts of rhizoma anemarrhenae, 8-15 parts of the membrane of a chicken's gizzard, 10-15 parts of pueraria lobata, 15-30 parts of root of Chinese trichosanthes, 10-15 parts of Herba Epimedii, Radix Codonopsis 10-15
Part, 10-15 parts of Rhizoma Atractylodis Macrocephalae, 8-10 parts of the root bark of tree peony, 8-10 parts of Schisandra chinensis, 15-25 parts of radix scrophulariae.
2. a kind of drug for treating diabetes as described in claim 1, by weight, including following raw material:
30 parts of Radix Rehmanniae, 25 parts of dogwood fruit, 15 parts of Radix Ophiopogonis, 15 parts of the stem of noble dendrobium, 80 parts of Chinese yam, 20 parts of Radix Astragali, 25 parts of rhizoma anemarrhenae, the membrane of a chicken's gizzard 10
Part, 15 parts of pueraria lobata, 25 parts of root of Chinese trichosanthes, 10 parts of Herba Epimedii, 15 parts of Radix Codonopsis, 15 parts of Rhizoma Atractylodis Macrocephalae, 10 parts of the root bark of tree peony, 10 parts of Schisandra chinensis, radix scrophulariae
25 parts.
3. a kind of drug for treating diabetes as claimed in claim 1 or 2, preparation method include the following steps:
(1)Bulk pharmaceutical chemicals are screened, are cleaned, drying takes each bulk pharmaceutical chemicals by weight;
(2)Each bulk pharmaceutical chemicals are crushed, 100-150 mesh sieve, mixing are crossed;
(3)By medicinal powder:The weight ratio of honey is 1:Medicinal powder is added in the honey for being heated to 80-100 DEG C by 1 ratio, stirring
Honey ointment is uniformly made, room temperature cools down to get honeyed bolus.
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CN108853130A (en) * | 2018-09-30 | 2018-11-23 | 北京济全生物科技有限公司 | A kind of hypoglycemic medicine composition and its preparation method and application comprising Catalpol |
CN109010299A (en) * | 2018-09-30 | 2018-12-18 | 北京济全生物科技有限公司 | A kind of sustained release hypoglycemic medicine composition and its preparation method and application |
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CN111281945A (en) * | 2020-03-10 | 2020-06-16 | 梁达钊 | Traditional Chinese medicine for treating diabetes |
CN111544544A (en) * | 2020-06-28 | 2020-08-18 | 广东药科大学 | Traditional Chinese medicine formula for treating senile type 2 diabetes |
CN114224973A (en) * | 2022-01-13 | 2022-03-25 | 孙天森 | Traditional Chinese medicine composition for treating diabetic ketosis |
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Publication number | Priority date | Publication date | Assignee | Title |
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CN108853130A (en) * | 2018-09-30 | 2018-11-23 | 北京济全生物科技有限公司 | A kind of hypoglycemic medicine composition and its preparation method and application comprising Catalpol |
CN109010299A (en) * | 2018-09-30 | 2018-12-18 | 北京济全生物科技有限公司 | A kind of sustained release hypoglycemic medicine composition and its preparation method and application |
CN108853130B (en) * | 2018-09-30 | 2019-08-13 | 北京济全生物科技有限公司 | A kind of hypoglycemic medicine composition and preparation method thereof |
CN110201111A (en) * | 2019-07-15 | 2019-09-06 | 王新 | A kind of anti-three high health care products or drug |
CN111281945A (en) * | 2020-03-10 | 2020-06-16 | 梁达钊 | Traditional Chinese medicine for treating diabetes |
CN111544544A (en) * | 2020-06-28 | 2020-08-18 | 广东药科大学 | Traditional Chinese medicine formula for treating senile type 2 diabetes |
CN114224973A (en) * | 2022-01-13 | 2022-03-25 | 孙天森 | Traditional Chinese medicine composition for treating diabetic ketosis |
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Application publication date: 20180925 |