CN108524568A

CN108524568A - Ginseng is fresh to carry spray-dried granules medicine materical crude slice

Info

Publication number: CN108524568A
Application number: CN201810733165.8A
Authority: CN
Inventors: 徐自升
Original assignee: Individual
Current assignee: Individual
Priority date: 2018-07-06
Filing date: 2018-07-06
Publication date: 2018-09-14

Abstract

The invention discloses a kind of " ginseng is fresh to carry spray-dried granules medicine materical crude slice ", are primarily characterized in that：Ginseng crude drug harvesting after, take advantage of it is fresh wash, be sliced, squeezing the juice, extracting, extracting solution concentration after be spray-dried, dried object crushing pelletize, dry again, after whole grain, vacuum packaging.The water content of finished particle medicine materical crude slice is less than 10%, contains ginsenoside Rg1（C₄₂H₇₂O₁₄）And ginsenoside Re（C₄₈H₈₂O₁₈）Total amount be not less than 0.40%.This prepared slice quality is stablized, and can both enter decoction decocting, can also directly enter capsule, tablet etc., is conducive to carry, Clinical practice is convenient.

Description

Ginseng is fresh to carry spray-dried granules medicine materical crude slice

Technical field

The invention belongs to prepared slices of Chinese crude drugs technical fields, especially belong to the manufacture field of Chinese medicine ginseng medicine materical crude slice.

Background technology

Chinese medicine ginseng is Araliaceae ginsengPanaxginseng C.A.Mey. dry root and rhizome.Often in the fall Excavation is dried or is dried after cleaning.The processing method of traditional sun-dried ginseng's medicine materical crude slice is the ginseng that will at source dry or dry Medicinal material, removing LU, stepping, add water soften or softened by baking after be sliced, dry, packaging.Such medicine materical crude slice volume is big, hygiene mark It is accurate poor, it is easy to make moist, mildew, carries worm's ovum, be unfavorable for taking care of, storage and transportation cost height.In addition, such prepared slice quality is steady Qualitative difference, clinical efficacy be difficult to ensure, patient takes inconvenience, works slow.Therefore, develop a kind of stable quality is reliable, storage/ Transportation cost is low, conducive to keeping, carry and easy to use, rapid-action novel ginseng medicine materical crude slice, it is imperative.Existing market someone Join Ultramicro-powder medicine materical crude slice and ginseng concentrated granular medicine materical crude slice, but both using conventional ginseng medicine materical crude slice as raw material, quality is decided by people Join the quality of medicine materical crude slice, and ultramicro decoction piece cannot solve the problems, such as that medicinal material pollutes；Concentrated granular can only extract water-soluble components.

Invention content

The invention discloses a kind of " ginseng is fresh to carry spray-dried granules medicine materical crude slice ", are primarily characterized in that：Ginseng crude drug adopts It after receipts, cleans, fresh clean silt is taken advantage of in 6 hours, the piece of 2 ~ 5mm thickness is cut into 24 hours；Extracting juice is pressed, adds 1 ~ 5 times in the dregs of a decoction The water of weight stirs 5 ~ 30 minutes, and filtering, dregs pressing takes juice；The water that 5 ~ 10 times of weight is added in the gained dregs of a decoction, boils 10 It ~ 30 minutes, filters while hot, the dregs of a decoction are squeezed the juice again, collect concoction；Merge above-mentioned concoction, be concentrated under reduced pressure, temperature is 50 ~ 70 DEG C, concentration To the concentrate that relative density is 1.02 ~ 1.10；Gained concentrate leaves and takes 1% ~ 3% spare, remaining concentrate spray drying, powder It is broken, it crosses 60 mesh and sieves to obtain spray powder；It is dry by this spray powder and above-mentioned spare concentrate mixing granulation, control particle water content Within 10%, it is vacuum-packed to get finished product；Finished product contains ginsenoside Rg1（C₄₂H₇₂O₁₄）And ginsenoside Re（C₄₈H₈₂O₁₈）'s Total amount must not be less than 0.40%.The clinical general usage amount of this medicine materical crude slice is 1 ~ 5g.This medicine materical crude slice can both enter decoction decoction or take after mixing it with water, and also may be used Directly enter in pill, powder, capsule and tablet.To substantially increase the convenience and compliance of Clinical practice, be conducive to The treatment of clinical acute disease.

Specific embodiment

It after ginseng crude drug is harvested, cleans, removes impurity and reed head, fresh clean silt is taken advantage of in 4 hours, and in 12 hours It is inside cut into the piece of 3mm thickness, presses extracting juice.In the gained dregs of a decoction plus the water of 5 times of weight, stirring 30 minutes, filtering, the dregs of a decoction squeeze take again Juice.The water that 8 times of weight is added in second of gained dregs of a decoction, boils 20 minutes and extracts, filter while hot, and the dregs of a decoction are squeezed the juice again, are received Collect concoction.Merge above-mentioned concoction, be concentrated under reduced pressure, temperature is to be set as 70 DEG C, and it is 1.05 to be concentrated into relative density.Gained concentrate 1% ~ 3% spare, remaining concentrate spray drying, crushing are left and taken, 60 mesh excessively sieve to obtain spray powder.By this spray powder with it is above-mentioned spare Concentrate mixing granulation, dry, control particle water content is vacuum-packed within 10% to get finished product.Medicine materical crude slice finished product contains people Join saponin(e Rg1（C₄₂H₇₂O₁₄）And ginsenoside Re（C₄₈H₈₂O₁₈）Total amount be not less than 0.40%.

Claims

1. a kind of ginseng is fresh to carry spray-dried granules medicine materical crude slice, it is primarily characterized in that：After ginseng crude drug's harvesting, clean, in 6 hours Fresh clean silt is taken advantage of, the piece of 2 ~ 5mm thickness is cut into 24 hours；Extracting juice is pressed, the water of 1 ~ 5 times of weight, stirring 5 ~ 30 are added in the dregs of a decoction Minute, filtering, dregs pressing takes juice；The water that 5 ~ 10 times of weight is added in the gained dregs of a decoction is boiled 10 ~ 30 minutes, is filtered while hot, The dregs of a decoction are squeezed the juice again, collect concoction；Merge above-mentioned concoction, be concentrated under reduced pressure, temperature be 50 ~ 70 DEG C, be concentrated into relative density be 1.02 ~ 1.10 concentrate；Gained concentrate leaves and takes 1% ~ 3% spare, remaining concentrate spray drying, crushing, and 60 mesh excessively sieve to obtain spray drying Powder；Dry by this spray powder and above-mentioned spare concentrate mixing granulation, control particle water content is within 10%, vacuum packet Dress is to get finished product；Finished product contains ginsenoside Rg1（C₄₂H₇₂O₁₄）And ginsenoside Re（C₄₈H₈₂O₁₈）Total amount must not be less than 0.40%。

2. ginseng according to claim 1 is fresh to carry spray-dried granules medicine materical crude slice, it is primarily characterized in that：Clinic generally uses Amount is 1 ~ 5g, this medicine materical crude slice can both enter decoction decoction, and also can directly enter in capsule and tablet.