CN108522511A - A kind of bactericidal composition containing eugenol and kasugarnycin - Google Patents
A kind of bactericidal composition containing eugenol and kasugarnycin Download PDFInfo
- Publication number
- CN108522511A CN108522511A CN201810775919.6A CN201810775919A CN108522511A CN 108522511 A CN108522511 A CN 108522511A CN 201810775919 A CN201810775919 A CN 201810775919A CN 108522511 A CN108522511 A CN 108522511A
- Authority
- CN
- China
- Prior art keywords
- kasugarnycin
- eugenol
- bactericidal composition
- composition containing
- tomato
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/02—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms
- A01N43/04—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom
- A01N43/14—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom six-membered rings
- A01N43/16—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom six-membered rings with oxygen as the ring hetero atom
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N31/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic oxygen or sulfur compounds
- A01N31/08—Oxygen or sulfur directly attached to an aromatic ring system
- A01N31/16—Oxygen or sulfur directly attached to an aromatic ring system with two or more oxygen or sulfur atoms directly attached to the same aromatic ring system
Abstract
The invention discloses a kind of bactericidal composition containing eugenol and kasugarnycin, active constituent includes eugenol and kasugarnycin;The weight ratio of the active component eugenol and kasugarnycin is 1:30~10:1, weight percent of the two weight summation in bactericidal composition is 1%~30%;This bright bactericidal composition has apparent synergistic effect, can prevent multiple diseases, especially good to graw mold of tomato and leaf muld of tomato preventive effect, good to the safety of crop, also has the advantages that quick after medicine, resistance of rainwater washing against, lasting medicine.
Description
Technical field
The invention belongs to technical field of pesticide, are related to a kind of bactericidal composition containing eugenol and kasugarnycin, described
Bactericidal composition is used for the purposes of controlling plant diseases.
Background technology
Eugenol, chemical name:Coryophyllic acid is botanical fungicide.Eugenol is therefrom
The active constituent of a kind of natural, green, environmental protection extracted in medicine, can be used for antibacterial, anti-inflammatory, agriculturally can be used in medicine
To the prevention that corps diseases rise, such as to gray mold, powdery mildew, downy mildew, leaf mold, anthracnose, rust, droop, epidemic disease
There is favorable effect.
Kasugarnycin belongs to antibiotics fungicide, has protection, treatment and a stronger systemic activity, permeability and strong,
It can be moved in plant, therapeutic effect is notable, quick after spray, and resistance of rainwater washing against, the lasting period is long, and kasugarnycin can be prevented
Control the various bacteria and fungal disease such as rice blast, leaf muld of tomato, white powder on the crops such as vegetables, melon and fruit and rice
The favourable agents of disease, cucumber bacterial angular leaf spot, Seed detection, fruit and vegetable anthracnose etc..
The prevention of many corps diseases at present can be just effectively controlled by chemical prevention, is used for a long time single
One chemical control causes the resistance problem of disease and the pollution problem that environment is different degrees of.Therefore, chemical pesticide is reduced
Use, have become the inexorable trend of agricultural chemicals research and development using environmentally protective biological pesticide prevention pest and disease damage.The present invention is unexpected
Ground find by eugenol with spring thunder is mould is re-dubbed composition, multiple kinds of crops disease can not only be prevented, moreover it is possible to solve a variety of diseases
Harmful resistance problem, and eugenol and the mould two kinds of medicaments of spring thunder are all green environment protective biological pesticides, it is environmentally friendly.
Invention content
The object of the present invention is to provide it is a kind of it is environmentally friendly, can overcome or delay drug resistance and make with synergistic
Bactericidal composition, the bactericidal composition active component includes eugenol and kasugarnycin.
To achieve the above object, the technical solution adopted in the present invention is:
A kind of bactericidal composition containing eugenol and kasugarnycin, including usual auxiliaries, eugenol and kasugarnycin,
The weight ratio of the active component eugenol and kasugarnycin is 1:30~10:1.
Further, the weight ratio of the active component eugenol and kasugarnycin is 1:20~7:1
Further, the weight ratio of the active component eugenol and kasugarnycin is 1:15~5:1.
Weight percent of the weight summation of eugenol and kasugarnycin in bactericidal composition is in the composition
1%~30%.
Further, weight of the weight summation of eugenol and kasugarnycin in bactericidal composition in the composition
Percentage is 1%~15%.
A kind of bactericidal composition containing eugenol and kasugarnycin of the present invention, further includes auxiliary agent and excipient.
Further, the bactericidal composition of offer of the invention can pass through Pesticide formulation side well known to pesticide field
Method is prepared into any one dosage form for being suitble to use in agricultural production.
Further, the dosage form includes preferably suspending agent, aqua, aqueous emulsion, wettable powder, soluble concentrate.
The composition of the present invention can include one or more auxiliary agents, as being known in the art.Used in composition
Auxiliary agent will apply the mode of preparation depending on preparation type and terminal user.
The auxiliary agent and excipient being suitble in the present composition are all usual formulation adjuvants or component, are such as carried
Body, surfactant, solvent, aqueous emulsion, stabilizer, synergist, antifoaming agent, thickener, water and inert filler.This analog assistant
It is known in the art and is commercially available.Their purposes in the preparation of embodiments of the present invention composition are to this
It is obvious for field technology personnel.
Further, bactericidal composition of the invention selects to apply side according to the difference of target object and use environment
Formula, such as spray, spread fertilizer over the fields, pouring, any one in trickle irrigation.
Further, pesticide synergistic composition of the invention is according to factors such as different crops, administration time, weather conditions
Difference, usage amount can change in a wider scope.
Further, bactericidal composition of the invention can also contain other pesticide activity components, such as with insecticide, mite killing
Agent, nematicide, fungicide, bactericide, virucide, fertilizer, plant growth regulator etc. are used in mixed way, to expand
The dosage of the prevention spectrum and reduction active ingredient that can prevent.
The invention solves the defect existing in the background technology, and the present invention has following advantageous effect:
1, in the active component of the present composition, eugenol belongs to botanical fungicide, and kasugarnycin belongs to antibiosis
Plain series bactericidal agent, both for green environment protective biological pesticide, environmentally friendly safety.
2, the composition after active component eugenol of the invention and kasugarnycin compound, compares single dose, to crops
The prevention of disease has significant synergistic effect, reduces the dosage of pesticidal preparations, reduces production cost.
3, the active component eugenol and the kasugarnycin mechanism of action are different, increase the effect to target organisms
Site expands prevention spectrum, has higher work to gray mold, leaf mold, black rot, rice blast, epidemic disease, powdery mildew, downy mildew
Property;
4, the composition overcomes or has delayed the drug resistance of harmful organism compared with single dose, extends the use of medicament
Service life.
Specific implementation mode
Preferably to describe the present invention, following exemplary embodiment is provided.Content mentioned by embodiment cannot recognize
To be limitation of the invention, the selection of material prescription can be according to actual conditions by other equivalent or replacing with similar purpose
It is replaced for feature.That is, being such as not particularly limited, each feature is a series of equivalent or similar characteristics a example, this
The protection domain of the technical solution of invention is subject to claim and is limited.
One, indoor biological determination of activity
1, subjects:Graw mold of tomato and leaf muld of tomato
2, test method:Test method refers to《The 4th part of farm-chemical indoor determination test rule fungicide:Inhibit disease
Fungal pathogens mycelia growth test Plating》With《The 6th part of farm-chemical indoor determination test rule fungicide:The joint of mixture
Effect measures》.
By the medicinal 0.1% Tween-80 surface-active of mother of advance prepared eugenol and kasugarnycin combination preparation
Agent aqueous dissolution, it is spare.Aseptically, with the card punch of a diameter of 0.5cm in the graw mold of tomato bacterium colony for cultivating 2d
Leaf muld of tomato bacterium colony edge behind edge and culture purified is beatened to take bacteria cake, by two kinds of pure culture biscuits involvng inoculations to contain eugenol and spring
Thunder mycin active ingredient is sterile water in the PDA culture medium of 0.125mg/L, 0.25mg/L, 0.5mg/L, 0.75mg/L, 1mg/L
Compare (CK1), each processing is repeated 4 times.25 DEG C of cultures, when bacterium colony covers with plate in compareing, are surveyed using crossing method
The colony diameter of amount control and processing, acquires colony diameter average value.Mycelial growth inhibition rate is calculated according to the following formula:
The toxicity index and co-toxicity coefficient that medicament is calculated according to Sun Yunpei's Method, it is (logical by standard agent of a certain single dose in mixture
Often selection EC50Junior) it calculates, test result such as table 1, table 2:
1 eugenol of table and indoor biological determination of activity of the kasugarnycin composite preparation to graw mold of tomato
As known from Table 1, eugenol and kasugarnycin are 1:30~10:Compounding in 1 range, to the interior of graw mold of tomato
Determination of activity, co-toxicity coefficient are all higher than 120, show in underrange, have synergistic function to graw mold of tomato, that two
Person's compound proportion is 3:When 4, synergy is the most notable, co-toxicity coefficient 188.33.
2 eugenol of table and indoor biological determination of activity of the kasugarnycin composite preparation to leaf muld of tomato
As shown in Table 2, eugenol and indoor biological determination of activity of the kasugarnycin composite preparation to leaf muld of tomato,
The two weight ratio is 1:30~10:In 1 range, co-toxicity coefficient is all higher than 120, illustrates the two 1:30~10:Mixture in 1 range
Synergistic effect is shown, especially when the proportioning of eugenol and kasugarnycin is 2:Co-toxicity coefficient is maximum when 3, synergistic effect
It is the most apparent.
Two, example of formulations
Embodiment 1:2% eugenol kasugarnycin aqua
Above-mentioned formula is pre-mixed in proportion, add blender be uniformly mixed obtain 2% eugenol
Kasugarnycin aqua.
Embodiment 2:3.3% eugenol kasugarnycin aqueous emulsion
Above-mentioned material is mixed in proportion, after high shear agitation is uniform, you can 3.3% eugenol spring thunder is made
Mycin aqueous emulsion.
Embodiment 3:12% eugenol kasugamycin water-dispersion granule
After each component is mixed by above-mentioned formula, after ultra-fine pulverizer disintegrating, be granulated, dried, sieve after sample
Analysis can be prepared by 12% eugenol kasugamycin water-dispersion granule.
Embodiment 4:24% eugenol kasugarnycin aqua
Above-mentioned formula is pre-mixed in proportion, add blender be uniformly mixed obtain 24% eugenol
Kasugarnycin aqua.
Embodiment 5:5% eugenol kasugarnycin wettable powder
Above-mentioned material is mixed in proportion, after mechanical crushing again through air-flow crushing, after mixing, you can be made 5% fourth
Eugenol kasugarnycin wettable powder.
Embodiment 6:7% eugenol kasugarnycin suspending agent
Above-mentioned each component is put into sand mill and is fully crushed to reasonable grain size, can be prepared by 7% clove tree through filtering
Phenol kasugarnycin suspending agent.
Three, field trial
1, subjects:Graw mold of tomato and leaf muld of tomato
2, reagent agent:Treatment agent is the combination preparation of embodiment 1-6, and comparison medicament suspends for 0.3% eugenol
Agent and 2% kasugarnycin aqua, the clear water for spraying isodose are blank control.
3, the test method of graw mold of tomato is prevented:Test arrangement is fallen ill heavier plot throughout the year in graw mold of tomato,
Graw mold of tomato early stage carries out dispenser, and the investigation drug effect method after investigating and preventing before dispenser is each to handle 4 cells
It repeats, 20 square metres of each plot area, the 5 points of samplings of each cell, every is investigated two plants, the whole fruits of every plant of investigation.According to
National field trial relevant criterion carries out severity Scaling, investigates disease indexs and calculates preventive effect within 7,14 days after dispenser, tries
It tests and the results are shown in Table 3:
4, the test method of leaf muld of tomato is prevented:Test arrangement is big in leaf muld of tomato heavier greenhouse of falling ill throughout the year
Canopy has plastic film mulching, spacing in the rows 35cm, line-spacing 70cm after tomato transplanting.Each experimental plot cultivation, fertilizer and water management etc. are consistent.
Using AGROLEX Singapore profit agriculture knapsack hand sprayer positive and negative even spraying, clear water control is first sprayed, same medicament is by low
Dosage carries out successively to high dose.Investigation method is with reference to pesticide field efficacy medicine test criterion (two).Each random 5 points of cell takes
Sample, every is investigated 2 plants, and every plant is divided upper, middle and lower to investigate 10 leaves, before dispenser, 7d, the 2nd dispenser after the 1st dispenser
7d investigates field incidence, the sick number of sheets of record investigation and sick grade afterwards, calculates reagent agent and respectively handles disease index and preventive effect.
Leaf muld of tomato disease leaf grade scale:0 grade:Disease-free spot;1 grade:Lesion area accounts for 5% or less entire leaf area;3
Grade:Lesion area accounts for entire leaf area 6%~10%;5 grades:Lesion area accounts for entire leaf area 11%~20%;7 grades:Scab
Area accounts for entire leaf area 21%~50%;9 grades:Lesion area accounts for 50% or more entire leaf area.
3 eugenol of table is with kasugarnycin composite preparation to the field control effectiveness test of graw mold of tomato
Eugenol and kasugarnycin built composition for preventing and controlling are can be seen that from the above field control effectiveness test result of table 3
Graw mold of tomato is with obvious effects to be better than single dose, and when effective ingredient consumption is 10 grams/ha, preventive effect is above 80%, quick-acting and
Lasting effect is above the preventive effect under the conditions of single dose, has no adverse effects to target crop in experiment scope of medication.
4 eugenol of table is with kasugarnycin composite preparation to the field control effectiveness test of leaf muld of tomato
As can be seen from Table 4, leaf muld of tomato can be effectively prevented after eugenol and kasugarnycin compounding, control effect is equal
Better than comparison medicament, in the case where dosage is reduced, control effect is greatly enhanced, and the lasting period is long, 7d preventive effects after dispenser
Up to 80% or more, 14d preventive effects have no adverse effects to target crop in experiment scope of medication up to 85% or more after dispenser.
Based on the above description of the preferred embodiments of the present invention, through the above description, related personnel completely can be with
Without departing from the scope of the technological thought of the present invention', various changes and amendments are carried out.The technical scope of this invention
It is not limited to the contents of the specification, it is necessary to determine the technical scope according to the scope of the claims.
Claims (8)
1. a kind of bactericidal composition containing eugenol and kasugarnycin, which is characterized in that the bactericidal composition active constituent
Including eugenol and kasugarnycin, the weight ratio of the active component eugenol and kasugarnycin is 1:30~10:1.
2. a kind of bactericidal composition containing eugenol and kasugarnycin according to claim 1, it is characterised in that:It is described
The weight ratio of bactericidal composition active component eugenol and kasugarnycin is 1:20~7:1.
3. a kind of bactericidal composition containing eugenol and kasugarnycin according to claim 1, it is characterised in that:It is described
The weight ratio of bactericidal composition active component eugenol and kasugarnycin is 1:15~5:1.
4. a kind of bactericidal composition containing eugenol and kasugarnycin according to claim 1, it is characterised in that:It is described
In bactericidal composition weight percent of the weight summation of eugenol and kasugarnycin in bactericidal composition be 1%~
30%.
5. a kind of Bactericidal composite containing eugenol and kasugarnycin according to any one of claim 1-4 claims
Object, it is characterised in that:The bactericidal composition can be prepared into arbitrarily by Pesticide formulation method well known to pesticide field
A kind of dosage form used in suitable agricultural production.
6. a kind of bactericidal composition containing eugenol and kasugarnycin according to claim 5, it is characterised in that:It is described
Dosage form includes suspending agent, aqua, aqueous emulsion, wettable powder, soluble concentrate.
7. a kind of bactericidal composition containing eugenol and kasugarnycin according to claim 1, it is characterised in that:It is described
Bactericidal composition is used for the purposes of controlling plant diseases.
8. a kind of bactericidal composition containing eugenol and kasugarnycin according to claim 7, it is characterised in that:It is described
Plant disease is graw mold of tomato and leaf muld of tomato.
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Cited By (2)
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CN113367138A (en) * | 2021-07-17 | 2021-09-10 | 湖南省水稻研究所 | Ecological pesticide for organic rice planting |
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Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
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CN110521723A (en) * | 2019-09-17 | 2019-12-03 | 扬州诺丰农业科技有限公司 | A kind of sulfonylation chitosan microcapsules preparation of the diseases such as efficient prevention and control eliminating vegetable botrytis |
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CN113367138A (en) * | 2021-07-17 | 2021-09-10 | 湖南省水稻研究所 | Ecological pesticide for organic rice planting |
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