CN108498643A - A kind of Chinese medicine for treating nasosinusitis - Google Patents

Abstract

The present invention relates to a kind of Chinese medicines for treating nasosinusitis, it is prepared by the raw medicinal material of following weight proportion：6 parts of yellow chrysanthemum flower, 6 parts of tribulus terrestris, 6 parts of fructus viticis, 3 parts of uncaria, 6 parts of the achene of Siberian cocklebur, 3 parts of the root of Dahurain angelica, 6 parts of Jehol Ligusticum Rhizome, 3 parts of Radix Glycyrrhizae.Clinical experiments have proved that the present invention can safely and effectively treat nasosinusitis.

Description

A kind of Chinese medicine for treating nasosinusitis

Technical field

The present invention relates to a kind of Chinese medicines, and in particular to a kind of Chinese medicine for treating nasosinusitis.

Background technology

Nasosinusitis, that is, nasal cavity inflammatory disease is virus, bacterium, allergen, various physical and chemical factors and certain systemic diseases The inflammation of bronchia mucosal caused by disease.The main pathological change of nasosinusitis is bronchia mucosal hyperemia, swelling, exudation, hyperplasia, atrophy Or necrosis etc..Chinese medicine is also known as nasosinusitis.

Nasosinusitis refers to thin nasal discharge, if the nether world oozes, measures more more than rhinopathys for main feature.Normal companioned with headache has a stuffy nose, smells Feel decline, nasal sinus area pain, long then it is empty it is dizzy endlessly.It is one of nose section common disease, frequently-occurring disease.Also there are " brain leakage ", " brain sand ", " brain Collapse ", the title of " brain deep pool ".Mostly because affection of exogenous wind-heat cult poison or chill are invaded, change heat long, heat symptoms caused by an exopathgen are followed through upper steaming, criminal and nose key；Or Gallbladder channel is hot, with through upper criminal, steams the nose key that burns；Or it is damp heat in the spleen and the stomach, it follows in stomach to disturb etc. and causes.

Before more than 2,000 years《Plain Questions is lost consciousness opinion》In just have such record：" nasosinusitis person, turbid tears stream is incessantly ", Illustrate people it has long been recognized that nasosinusitis is with turbid nasal discharge, it is incessantly the rhinopathys of main feature to measure more.This disease is clinically normal See, frequently-occurring disease, men and women, old and young can illness, and it is common with teenager.It is equivalent to the purulent sinusitis of western medicine.On nasal sinus is Jaw sinus, sinus frontalis, sieve sinus, sphenoid sinus general name, each Dou Jun have opening and communicated with nasal cavity.Lesion both can individually occurs in they, Can it is multiple or all there is inflammation, be commonly referred to as nasosinusitis.This disease has anxious nasosinusitis（Acute purulent nasosinusitis）With slow nasosinusitis（It is chronic Purulent sinusitis）Two types, and it is more common with the latter.

Medicinal material present Research involved in the present invention is as follows：

Yellow chrysanthemum flower【Source】This product is the drying cephaloid of feverfew chrysanthemum Chrysanthemum morifolium Ramat. Sequence.It harvests, dry in the shade or dries in batches when 9~November spends in full bloom, or dried after smoked, steaming.Medicinal material is different by the place of production and processing method, It is divided into " Bo chrysanthemum ", " chu chrysanthemum ", " tribute chrysanthemum ", " Hang Ju ".This product is advisable with Hang Ju【Nature and flavor】It is sweet, bitter, it is slightly cold.【Channel tropism】Return Lung, Liver Channel.【Major function】Relieve heat heat-clearing, flat liver improving eyesight.For anemopyretic cold, dizziness of having a headache, red eye, swell pain, eyes is dim-sighted. 【Usage and dosage】5~9g.

Tribulus terrestris【Source】This product is the drying and ripening fruit of zygophyllaceae plant puncture vine Tribulus terrestris L. It is real.Plant is tapped when the fruit matures in the fall, is dried, fruit is laid, and removes impurity.【Nature and flavor】It is pungent, bitter, tepor；It is slightly poisonous.【Return Through】Return liver warp.【Major function】Flat liver solution strongly fragrant, promoting blood circulation by removing wind, improving eyesight are antipruritic.For dizziness of having a headache, distending pain in the chest and hypochondrium, breast closes Acute mastitis, cataract, rubella itch.【Usage and dosage】6~9g.

Fructus viticis【Source】This product is Verbenaceae Vitex rotundifolia Vitex trifolia L. var. The dry mature fruit of simplicifolia Cham. or wild pepper Vitex trifolia L..It harvests when the fruit matures in the fall, Impurity is removed, is dried.【Nature and flavor】It is pungent, bitter, it is slightly cold.【Channel tropism】Return bladder, liver, stomach.【Major function】Dispelling wind and heat from the body, clearly The sharp head.It has a headache for anemopyretic cold, gingivitis, the more tears of hot eyes, mesh is secretly unknown, has a dizzy spell.【Usage and dosage】5~9g.

Uncaria【Source】This product is madder wort uncaria Uncaria rhynch0phylla（Miq.）Jacks., greatly Leaf uncaria Uncaria macrophylla Wall., uncaria hirsuta Uncaria hirsuta Havil., Uncaria sinensis Uncaria sinensis （Oliv.）Or the drying buckle stem of stockless fruit uncaria Uncaria sessilifructus Roxb. Havil. Branch.Autumn, the harvesting of two season of winter, defoliation, segment are dried.【Nature and flavor】It is sweet, it is cool.【Channel tropism】Return liver, pericardium channel.【Major function】Clearly Hot soothing the liver, dispelling wind and relieving convulsion.For dizziness of having a headache, dysphoric cold, twitch, pre-eclampsia；Hypertension.【Usage and dosage】3~ 12g。

The achene of Siberian cocklebur【Source】This product is the drying and ripening of feverfew Siberian cocklebur Xanthium sibiricum Patr. with involucre Fruit.It harvests when the fruit matures in the fall, it is dry, remove the impurity such as stalk, leaf.Herb can also be used as medicine.【Nature and flavor】It is pungent, bitter, temperature；Have Poison.【Channel tropism】It is distributed in lung channel.【Major function】The achene of Siberian cocklebur：Relieve heat dehumidifies, clearing the nasal passage.For anemofrigid headache, nasosinusitis runny nose, rubella Itch, arthritis with fixed pain caused by dampness contraction.【Usage and dosage】3~9g of the achene of Siberian cocklebur.

The root of Dahurain angelica【Source】This product is umbellate form section plant root of Dahurain angelica Angelica dahurica（Fisch.ex Hoffm.） Benth. et Hook.f. or Radix angelicae dahuricae Angelica dahurica（Fisch.ex Hoffm.） Benth.et Hook.f. var.formosana（Boiss.）The dry root of Shan et Yuan.It is excavated when leaf Huang between summer, autumn, removes fibrous root and silt, Dry or low temperature dry.【Nature and flavor】It is acrid in flavour and warm in nature.【Channel tropism】Return stomach, large intestine, lung channel.【Major function】Relieve heat dehumidifies, sensible to stop Bitterly, detumescence and apocenosis.For cold headache, pain in the supra-orbital bone, nasal obstruction, nasosinusitis, toothache, leukorrhea, sore swell and ache curative.【Usage and dosage】3~ 9g。

Jehol Ligusticum Rhizome【Source】This product is Umbelliferae Jehol Ligusticum Rhizome platymiscium Jehol Ligusticum Rhizome Ligusticum sinense Oliv. or Ligusticum jeholense The dry rhizome and root of Ligusticum jeholense Nakai et Kitag..When autumn cauline leaf is withered or secondary spring is emerged Excavation removes silt, dries or dry.【Nature and flavor】It is acrid in flavour and warm in nature.【Channel tropism】Return bladder warp.【Major function】Wind-dispelling, cold dispelling remove It is wet, analgesic.For anemofrigid cold, pain, rheumatism podomere numbness pain are pushed up in mountain peak.【Usage and dosage】3~9g.

Radix Glycyrrhizae【Source】This product is glycyrrhizic legume Glycyrrhiza uralensis Fisch., swollen fruit Radix The dry root of Glycyrrhiza inflata Bat. or glycyrrhiza glabra Glycyrrhiza glabra L..Spring, Qiu Erji Excavation removes fibrous root, dries.【Nature and flavor】Sweet and neutral.【Channel tropism】The thoughts of returning home, lung, spleen, stomach.【Major function】It invigorates the spleen and benefits qi, It is clearing heat and detoxicating, expelling phlegm and arresting coughing, relieving spasm to stop pain, coordinating the drug actions of a prescription.For weakness of the spleen and the stomach, lassitude hypodynamia, palpitation, coughing with a lot of sputum, Gastral cavity abdomen, four limbs contraction, carbuncle sore tumefacting virus alleviate drug toxicity, strong.【Usage and dosage】1.5~9g.

Invention content

The present invention is intended to provide a kind of Chinese medicine for treating nasosinusitis is reached by selecting suitable medicinal material and its proportioning To the safe and effective purpose for curing nasosinusitis.

In order to achieve the above object, the present invention uses following technical scheme：

A kind of Chinese medicine for treating nasosinusitis, which is characterized in that it is prepared by the raw medicinal material of following weight proportion： 6 parts of yellow chrysanthemum flower, 6 parts of tribulus terrestris, 6 parts of fructus viticis, 3 parts of uncaria, 6 parts of the achene of Siberian cocklebur, 3 parts of the root of Dahurain angelica, 6 parts of Jehol Ligusticum Rhizome, 3 parts of Radix Glycyrrhizae.

Inventor thinks that nasosinusitis is lost by ferritic insufficiency of natural endowment or the day after tomorrow in maintenance, causes liver and gall heat solid stagnant very and by ailment said due to cold or exposure It does not understand, controls and preferably let out liver and gall, dispelling wind evil clearly with three sun and control therefore assemble we.

The beneficial effects of the present invention will now be described with reference to clinical experimental data：

1, general information

Outpatient service and in hospital sinusitis in patients 96 are collected in inventor in August, 2011 ~ 2013 year altogether between May, are randomly divided into treatment group 48 and control group 48, treatment group man 24, female 24,20~45 years old age, average age 37.3 years old, the course of disease 1~3 year； Control group man 26, female 22,22~45 years old age, average age 37.9 years old, the course of disease 1~3 year.2 groups of genders, age and the course of disease Comparing difference is not statistically significant, is comparable.

Diagnostic criteria

It is effective：The cardinal symptoms such as headache, dizzy, face swollen sample, nasal obstruction, purulent secretion disappear, and nasal endoscopes are in order, intranasal Without apparent purulence sample deposit.Effectively：The cardinal symptoms such as headache, dizzy, face swollen sample, nasal obstruction, purulent secretion mitigate, intranasal heap Product object is reduced, but CT examination imaging is more fuzzy.In vain：Cardinal symptom does not have remarkable improvement or exacerbation.

2 therapies

The oral present invention for the treatment of group is according to decoction made from specific embodiment 1,3 times a day.The course for the treatment of 16 weeks.

Control group oral azithromycin（Execution standard《Chinese Pharmacopoeia》2010 Nian Banerbu Qilu Pharmaceutical Co., Ltd.）, It is taken according to its specification.The course for the treatment of 16 weeks.

3, treatment results

Treatment results are shown in Table 1.

1 two groups of curative effects of table compare

Group	n	It is effective	Effectively	In vain	Total effective rate (%)	Serious adverse reaction example
							Treatment group	48	15	27	6	87.50%	0
Control group	48	12	20	16	66.67%	0

As it can be seen that drug produced by the present invention can safely and effectively treat nasosinusitis, there is promotional value.

Specific implementation mode

In order to better understand with the implementation present invention, further illustrated the present invention with reference to specific embodiment.

Specific embodiment 1

It weighs：6 grams of yellow chrysanthemum flower, 6 grams of tribulus terrestris, 6 grams of fructus viticis, 3 grams of uncaria, 6 grams of the achene of Siberian cocklebur, 3 grams of the root of Dahurain angelica, 6 grams of Jehol Ligusticum Rhizome, Radix Glycyrrhizae 3 grams；Add 8 times of amount water, decocts 1.5 hours, filtering；Filter residue adds 6 times of amount water, decocts 1 hour, filtering；Merging filtrate is concentrated into 120 grams to get meeting the decoction of one day dosage of normal adult.

For treating nasosinusitis.It is oral, it is taken three times in the morning, afternoon and evening per bu.

Specific embodiment 2

It weighs：6 grams of yellow chrysanthemum flower, 6 grams of tribulus terrestris, 6 grams of fructus viticis, 3 grams of uncaria, 6 grams of the achene of Siberian cocklebur, 3 grams of the root of Dahurain angelica, 6 grams of Jehol Ligusticum Rhizome, Radix Glycyrrhizae 3 grams；Add 10 times of amount water, decocts 2 hours, filtering；Filter residue adds 8 times of amount water, decocts 1.5 hours, filtering；Merging filtrate concentrates, and does It is dry, it packs to get the powder of one day dosage of normal adult is met.

For treating nasosinusitis.It is oral, daily once.

Specific embodiment 3

It weighs：6 grams of yellow chrysanthemum flower, 6 grams of tribulus terrestris, 6 grams of fructus viticis, 3 grams of uncaria, 6 grams of the achene of Siberian cocklebur, 3 grams of the root of Dahurain angelica, 6 grams of Jehol Ligusticum Rhizome, Radix Glycyrrhizae 3 grams；Add 6 times of amount water, decocts 3 times, decoct 1 hour every time, merge decoction liquor, concentrate, it is dry, capsule shells are packed into get meeting The capsule of one day dosage of normal adult.

For treating nasosinusitis.It is oral, it is taken twice sooner or later per bu.

Claims (1)

1. a kind of for treating the Chinese medicine of nasosinusitis, which is characterized in that it be prepared by the raw medicinal material of following weight proportion and At：6 parts of yellow chrysanthemum flower, 6 parts of tribulus terrestris, 6 parts of fructus viticis, 3 parts of uncaria, 6 parts of the achene of Siberian cocklebur, 3 parts of the root of Dahurain angelica, 6 parts of Jehol Ligusticum Rhizome, 3 parts of Radix Glycyrrhizae.