CN108498386A - A kind of mosquito repellent composition and preparation method thereof - Google Patents
A kind of mosquito repellent composition and preparation method thereof Download PDFInfo
- Publication number
- CN108498386A CN108498386A CN201810487050.5A CN201810487050A CN108498386A CN 108498386 A CN108498386 A CN 108498386A CN 201810487050 A CN201810487050 A CN 201810487050A CN 108498386 A CN108498386 A CN 108498386A
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- Prior art keywords
- mosquito repellent
- repellent composition
- active constituent
- component
- smilax
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9728—Fungi, e.g. yeasts
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9794—Liliopsida [monocotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/02—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings containing insect repellants
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- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Engineering & Computer Science (AREA)
- Pest Control & Pesticides (AREA)
- Plant Pathology (AREA)
- Dermatology (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
The present invention relates to barrier formulation technical fields, are specifically related to a kind of mosquito repellent composition.The active constituent of the mosquito repellent composition includes the active constituent from following substance：Radix Paeoniae Alba, smilax.The present invention is without any side effects, and pollution-free, free from extraneous odour, repelling effect is good, and repelling effect is lasting.The invention further relates to a kind of preparation methods of mosquito repellent composition.
Description
Technical field
The present invention relates to barrier formulation technical fields, are specifically related to a kind of mosquito repellent using Chinese medicine as main active
Composition and preparation method thereof.
Background technology
During the broiling summer, mosquito-proof to be us must solve the problems, such as, bite by mosquitos not only results in human skin itch,
And the propagation of germ is also resulted in, most of infectious diseases are infected by bite by mosquitos.
Mosquito repellent product on the market generally contains pesticide composition or Synthetic Organic Chemistry substance.For example number of patent application is
The patent application of CN200910033381.2, it discloses a kind of mosquito-repellent waters, by salicylic acid, ethyl acetate, aromatic oil, adjacent benzene two
Formic acid dimethyl ester forms, and salicylic acid easily causes human skin sensitivity, stimulates skin.Number of patent application is
The patent application of CN201010570915.8, discloses a kind of mosquito-repellent water, in this mosquito-repellent water containing camphor, ethyl alcohol, propylene glycol,
The active ingredients such as citronella oil, eucalyptus citriodora oil and peppermint oil, but camphor smell is big, is not easy to be esthetically acceptable to the consumers.Such product warp
The discomfort that person poultry poisoning often occurs or has peculiar smell, stimulation to cause human brain.
Invention content
The one of purpose of the present invention is, provides a kind of mosquito repellent composition having no toxic side effect.
Above-mentioned purpose that the invention is realized by the following technical scheme：
A kind of mosquito repellent composition, active constituent include the active constituent from following substance：Radix Paeoniae Alba, smilax.
The active constituent of the mosquito repellent composition is prepared from the following raw materials in parts by weight as a preferred technical solution,：
3 parts of Radix Paeoniae Alba；1 part of smilax.
The active constituent of the mosquito repellent composition also includes the activity from following substance as a preferred technical solution,
Ingredient：Frutus cnidii, Cortex Phellodendri, the fruit of summer cypress, balsam pear skin, wrinkled giant hyssop, lotus leaf.
The active constituent of the mosquito repellent composition is prepared from the following raw materials in parts by weight as a preferred technical solution,：
3 parts of Radix Paeoniae Alba；1 part of smilax；1 part of frutus cnidii；1 part of Cortex Phellodendri；1 part of the fruit of summer cypress；1 part of balsam pear skin；1 part of wrinkled giant hyssop；1 part of lotus leaf.
As a preferred technical solution, the mosquito repellent composition be configured to lotion, creme, spray, paste, paint or
The form of solid.
It is a further object of the invention to provide a kind of preparation methods of mosquito repellent composition.
Above-mentioned purpose that the invention is realized by the following technical scheme：
A kind of preparation method of mosquito repellent composition, includes the following steps：
Step 1) prepares raw material by following weight ratio：3 parts of Radix Paeoniae Alba；1 part of smilax；1 part of frutus cnidii；1 part of Cortex Phellodendri；The fruit of summer cypress
1 part；1 part of balsam pear skin；1 part of wrinkled giant hyssop；1 part of lotus leaf；
The active constituent of frutus cnidii, Cortex Phellodendri, the fruit of summer cypress, balsam pear skin, wrinkled giant hyssop, lotus leaf is extracted with water in step 2), obtains component
One solution；
Step 3) the alcoholic extraction Radix Paeoniae Alba of a concentration of 40-60%, the active constituent of smilax, obtain two solution of component；
One solution of component and two solution of component obtains mosquito repellent composition by step 4) after mixing, wherein component one
Concentration expressed in percentage by volume is 60-80%, and the concentration expressed in percentage by volume of component two is 20-40%.
Compared with the prior art, the present invention has following advantageous effect：
1, the active constituent of mosquito repellent composition of the present invention derives from natural plants, without any side effects, pollution-free, is no different
Taste.
2, mosquito repellent composition repelling effect of the present invention is good, and repelling effect is lasting.
Specific implementation mode
In order to facilitate the understanding of those skilled in the art, further being retouched to the present invention below in conjunction with specific embodiment
It states.
Embodiment one
A kind of preparation method of mosquito repellent composition, includes the following steps：
Step 1) prepares raw material by following weight ratio：3 parts of Radix Paeoniae Alba；1 part of smilax；1 part of frutus cnidii；1 part of Cortex Phellodendri；The fruit of summer cypress
1 part；1 part of balsam pear skin；1 part of wrinkled giant hyssop；1 part of lotus leaf；
Step 2) decocts frutus cnidii, Cortex Phellodendri, the fruit of summer cypress, balsam pear skin, wrinkled giant hyssop, lotus leaf, the snake that will be extracted three times with water
Machine tool, Cortex Phellodendri, the fruit of summer cypress, balsam pear skin, wrinkled giant hyssop, lotus leaf decoction after mixing, obtain one solution of component；
Step 3) impregnates Radix Paeoniae Alba, smilax under room temperature (20-25 DEG C) with the edible alcohol of a concentration of 40-60%, by two
The secondary maceration extract for impregnating obtained Radix Paeoniae Alba, smilax after mixing, obtains two solution of component；
One solution of component and two solution of component obtains mosquito repellent composition by step 4) after mixing, wherein component one
Concentration expressed in percentage by volume is 60%, and the concentration expressed in percentage by volume of component two is 40%.
Embodiment two
A kind of preparation method of mosquito repellent composition, includes the following steps：
Step 1) prepares raw material by following weight ratio：3 parts of Radix Paeoniae Alba；1 part of smilax；1 part of frutus cnidii；1 part of Cortex Phellodendri；The fruit of summer cypress
1 part；1 part of balsam pear skin；1 part of wrinkled giant hyssop；1 part of lotus leaf；
Step 2) decocts frutus cnidii, Cortex Phellodendri, the fruit of summer cypress, balsam pear skin, wrinkled giant hyssop, lotus leaf, the snake that will be extracted three times with water
Machine tool, Cortex Phellodendri, the fruit of summer cypress, balsam pear skin, wrinkled giant hyssop, lotus leaf decoction after mixing, obtain one solution of component；
Step 3) impregnates Radix Paeoniae Alba, smilax under room temperature (20-25 DEG C) with the edible alcohol of a concentration of 40-60%, by two
The secondary maceration extract for impregnating obtained Radix Paeoniae Alba, smilax after mixing, obtains two solution of component；
One solution of component and two solution of component obtains mosquito repellent composition by step 4) after mixing, wherein component one
Concentration expressed in percentage by volume is 80%, and the concentration expressed in percentage by volume of component two is 20%.
Mosquito repellent is tested
Attack is tested
It is put into female aedes albopictus mosquito 400 in specification is 60*45*45CM mosquito cages, hand is stretched into mosquito cage by volunteer
In after 2 minutes, the test worm for coming to stop falling reaches 32, is more than 25, and test result shows that mosquito attack is qualified, volunteer and
It can be used for repellency test.
Human body repellency test
Each exposed 4*5CM skins, rest part tightly cover on both hands the back of the hand of attack pass the test person.Wherein 1
It is wet as blank control that hand uses water to apply, and tested drug is uniformly applied to the back of the hand by 1.5UL/CM2 and exposes skin by another 1 hand
It on skin, puts his hand into after twenty minutes in the mosquito cage of attack pass the test 2 minutes, right-hand man is as possible respectively close to left and right in cage
Cage wall, whether there is or not mosquitoes to come to suck blood for observation, tests 1 time within every 20 minutes later, records the average effective guard time of repellant simultaneously
Calculate Effective Vate of Protection.
Experiment uses RANDOMIZED BLOCK DESIGN, 3 repetitions.
Effective Vate of Protection (%)=(control group averagely stings thorn number-test group and averagely stings thorn number)/control group averagely stings thorn number *
100%
The mosquito repellent composition human body repellency test test result of 1 embodiment one of table
The mosquito repellent composition human body repellency test test result of 2 embodiment two of table
It can be obtained from table 1 and table 2, the Effective Vate of Protection of the mosquito repellent compositions of two embodiments in 40 minutes is up to 100%；
At 60 minutes the Effective Vate of Protection of the mosquito repellent composition of embodiment one be 93.76%, the mosquito repellent composition of embodiment two it is effective
Protective rate is 89.83%；The Effective Vate of Protection of the mosquito repellent composition of embodiment one is 74.13% at 80 minutes, embodiment two
The Effective Vate of Protection of mosquito repellent composition is 70.32%.Test result shows that after smearing mosquito repellent composition be effective in 40 minutes
Guard time, after forty minutes Effective Vate of Protection extend at any time and reduce.
Some embodiments of the invention above described embodiment only expresses, the description thereof is more specific and detailed, but simultaneously
Cannot the limitation to the scope of the claims of the present invention therefore be interpreted as.It should be pointed out that for those of ordinary skill in the art
For, without departing from the inventive concept of the premise, various modifications and improvements can be made, these belong to the guarantor of the present invention
Protect range.Therefore, the protection domain of patent of the present invention should be determined by the appended claims.
Claims (7)
1. a kind of mosquito repellent composition, which is characterized in that its active constituent includes the active constituent from following substance：Radix Paeoniae Alba,
Smilax.
2. mosquito repellent composition according to claim 1, it is characterised in that：The active constituent of the mosquito repellent composition is by following
The raw material of parts by weight is made：3 parts of Radix Paeoniae Alba；1 part of smilax.
3. mosquito repellent composition according to claim 1, which is characterized in that the active constituent of the mosquito repellent composition also includes
From the active constituent of following substance：Frutus cnidii, Cortex Phellodendri, the fruit of summer cypress, balsam pear skin, wrinkled giant hyssop, lotus leaf.
4. mosquito repellent composition according to claim 3, it is characterised in that：The active constituent of the mosquito repellent composition is by following
The raw material of parts by weight is made：3 parts of Radix Paeoniae Alba；1 part of smilax；1 part of frutus cnidii；1 part of Cortex Phellodendri；1 part of the fruit of summer cypress；1 part of balsam pear skin；The leaves of pulse plants
It is 1 part fragrant；1 part of lotus leaf.
5. according to claim 1-4 any one of them mosquito repellent compositions, it is characterised in that：The mosquito repellent composition is configured to
The form of lotion, creme, spray, paste, paint or solid.
6. being used to prevent the purposes of mosquito according to claim 1-4 any one of them mosquito repellent compositions.
7. a kind of preparation method of mosquito repellent composition, which is characterized in that include the following steps：
Step 1) prepares raw material by following weight ratio：3 parts of Radix Paeoniae Alba；1 part of smilax；1 part of frutus cnidii；1 part of Cortex Phellodendri；1 part of the fruit of summer cypress；
1 part of balsam pear skin；1 part of wrinkled giant hyssop；1 part of lotus leaf；
The active constituent of frutus cnidii, Cortex Phellodendri, the fruit of summer cypress, balsam pear skin, wrinkled giant hyssop, lotus leaf is extracted with water in step 2), and it is molten to obtain component one
Liquid；
Step 3) the alcoholic extraction Radix Paeoniae Alba of a concentration of 40-60%, the active constituent of smilax, obtain two solution of component；
One solution of component and two solution of component are obtained mosquito repellent composition, the wherein volume of component one by step 4) after mixing
Percentage concentration is 60-80%, and the concentration expressed in percentage by volume of component two is 20-40%.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810487050.5A CN108498386A (en) | 2018-05-21 | 2018-05-21 | A kind of mosquito repellent composition and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810487050.5A CN108498386A (en) | 2018-05-21 | 2018-05-21 | A kind of mosquito repellent composition and preparation method thereof |
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| Publication Number | Publication Date |
|---|---|
| CN108498386A true CN108498386A (en) | 2018-09-07 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN201810487050.5A Pending CN108498386A (en) | 2018-05-21 | 2018-05-21 | A kind of mosquito repellent composition and preparation method thereof |
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Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102973973A (en) * | 2012-12-28 | 2013-03-20 | 青岛信锐德科技有限公司 | Air-freshening bacteriostatic agent and preparation method thereof |
| CN103893058A (en) * | 2014-02-26 | 2014-07-02 | 高跃忠 | Traditional Chinese herbal medicinal mosquito repellant liquid |
| CN104397064A (en) * | 2014-10-30 | 2015-03-11 | 六安亿牛生物科技有限公司 | Breeding farm mosquito-pest-repelling Chinese herbal medicine preparation and preparation method thereof |
| CN104888459A (en) * | 2015-06-08 | 2015-09-09 | 庄可香 | Antibacterial lion-shaped toy |
| CN104887593A (en) * | 2015-07-05 | 2015-09-09 | 陈梦佳 | Pure vegetable natural mosquito-repellent liquid |
-
2018
- 2018-05-21 CN CN201810487050.5A patent/CN108498386A/en active Pending
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102973973A (en) * | 2012-12-28 | 2013-03-20 | 青岛信锐德科技有限公司 | Air-freshening bacteriostatic agent and preparation method thereof |
| CN103893058A (en) * | 2014-02-26 | 2014-07-02 | 高跃忠 | Traditional Chinese herbal medicinal mosquito repellant liquid |
| CN104397064A (en) * | 2014-10-30 | 2015-03-11 | 六安亿牛生物科技有限公司 | Breeding farm mosquito-pest-repelling Chinese herbal medicine preparation and preparation method thereof |
| CN104888459A (en) * | 2015-06-08 | 2015-09-09 | 庄可香 | Antibacterial lion-shaped toy |
| CN104887593A (en) * | 2015-07-05 | 2015-09-09 | 陈梦佳 | Pure vegetable natural mosquito-repellent liquid |
Non-Patent Citations (1)
| Title |
|---|
| 马汴梁: "《中医补肝养生法》", 31 January 2013, 人民军医出版社 * |
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Application publication date: 20180907 |
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