CN108472346A - 含有traf诱导结构域的嵌合受体及相关组合物和方法 - Google Patents

含有traf诱导结构域的嵌合受体及相关组合物和方法 Download PDF

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Publication number
CN108472346A
CN108472346A CN201680077930.4A CN201680077930A CN108472346A CN 108472346 A CN108472346 A CN 108472346A CN 201680077930 A CN201680077930 A CN 201680077930A CN 108472346 A CN108472346 A CN 108472346A
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cells
domain
cell
chimeric receptor
antigen
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Chinese (zh)
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L·J·汤普森
V·厄德高
B·萨瑟
A·布拉曼戴姆
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Juno Therapeutics Inc
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Juno Therapeutics Inc
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    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/70521—CD28, CD152
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CN201680077930.4A 2015-11-05 2016-11-04 含有traf诱导结构域的嵌合受体及相关组合物和方法 Pending CN108472346A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562251590P 2015-11-05 2015-11-05
US62/251,590 2015-11-05
PCT/US2016/060736 WO2017079705A1 (en) 2015-11-05 2016-11-04 Chimeric receptors containing traf-inducing domains and related compositions and methods

Publications (1)

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CN108472346A true CN108472346A (zh) 2018-08-31

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US (1) US20180319862A1 (https=)
EP (1) EP3370762A1 (https=)
JP (1) JP2018532432A (https=)
KR (1) KR20180082493A (https=)
CN (1) CN108472346A (https=)
AU (1) AU2016349724B2 (https=)
BR (1) BR112018008442A2 (https=)
CA (1) CA3002990A1 (https=)
MA (1) MA44314A (https=)
MX (1) MX2018005618A (https=)
WO (1) WO2017079705A1 (https=)

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CN111849910A (zh) * 2020-05-27 2020-10-30 南京北恒生物科技有限公司 工程化免疫细胞及其用途
CN112251452A (zh) * 2019-10-22 2021-01-22 上海斯丹赛生物技术有限公司 Til/tcr-t细胞治疗平台
CN113226359A (zh) * 2018-11-08 2021-08-06 耐克西缪恩有限公司 具有改进的表型特性的t细胞组合物
WO2021160120A1 (zh) * 2020-02-13 2021-08-19 北京艺妙神州医药科技有限公司 嵌合抗原受体的优化
CN113402612A (zh) * 2020-03-17 2021-09-17 西比曼生物科技（香港）有限公司 靶向cd19和cd20的联合嵌合抗原受体及其应用
WO2024140980A1 (zh) * 2022-12-30 2024-07-04 上药生物治疗（香港）有限公司 表达趋化因子受体的细胞及其用途
US12583903B2 (en) 2017-02-08 2026-03-24 AbelZeta Inc. Construction of chimeric antigen receptor targeting CD20 antigen and activity identification of engineered T cells thereof

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EP2948544A4 (en) 2013-01-28 2016-08-03 St Jude Childrens Res Hospital CHIMERIC RECEPTOR WITH NKG2D SPECIFICITY FOR CELL THERAPY AGAINST CANCER AND INFECTION DISEASES
AU2015259877B2 (en) 2014-05-15 2021-02-25 National University Of Singapore Modified natural killer cells and uses thereof
EP4400516A1 (en) 2014-12-15 2024-07-17 The Regents of the University of California Bispecific or-gate chimeric antigen receptor responsive to cd19 and cd20
EP3234120B1 (en) 2014-12-15 2025-09-03 The Regents of the University of California Cytotoxic molecules responsive to intracellular ligands for selective t cell mediated killing
CN107530424A (zh) 2015-02-20 2018-01-02 俄亥俄州国家创新基金会 针对nkg2d和肿瘤相关抗原的二价抗体
AU2016246457B2 (en) 2015-04-06 2020-10-15 Cytoimmune Therapeutics, Inc. EGFR-directed car therapy for glioblastoma
DK3368571T5 (da) 2015-10-30 2024-09-30 Univ California Transformerende, vækstfaktor-beta-responsive polypeptider og fremgangsmåder til anvendelse deraf
EP4089116A1 (en) 2016-09-27 2022-11-16 Cero Therapeutics, Inc. Chimeric engulfment receptor molecules
WO2018124766A2 (ko) 2016-12-28 2018-07-05 주식회사 녹십자랩셀 키메라 항원 수용체 및 이를 발현하는 자연 살해 세포
MX2019011570A (es) 2017-03-27 2019-11-18 Nat Univ Singapore Lineas celulares estimuladoras para expansion y activacion ex vivo de celulas asesinas naturales.
KR102660336B1 (ko) 2017-03-27 2024-04-26 내셔널 유니버시티 오브 싱가포르 절단된 nkg2d 키메라 수용체 및 자연 살해 세포 면역요법에서의 그의 용도
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