CN108452192A - A kind of drug for treating migraine - Google Patents

A kind of drug for treating migraine Download PDF

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Publication number
CN108452192A
CN108452192A CN201810193745.2A CN201810193745A CN108452192A CN 108452192 A CN108452192 A CN 108452192A CN 201810193745 A CN201810193745 A CN 201810193745A CN 108452192 A CN108452192 A CN 108452192A
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radix
chrysanthemum
drug
powder
rhizoma
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谭清平
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    • A—HUMAN NECESSITIES
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    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/236—Ligusticum (licorice-root)
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    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
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    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232—Angelica
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    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
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    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/26—Aristolochiaceae (Birthwort family), e.g. heartleaf
    • A61K36/268—Asarum (wild ginger)
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    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/287—Chrysanthemum, e.g. daisy
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    • A61K36/185—Magnoliopsida (dicotyledons)
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    • A61K36/481—Astragalus (milkvetch)
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    • A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
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    • A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
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    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/75—Rutaceae (Rue family)
    • A61K36/752—Citrus, e.g. lime, orange or lemon
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    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/80—Scrophulariaceae (Figwort family)
    • A61K36/804—Rehmannia
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    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
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    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/81—Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P25/06—Antimigraine agents

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Abstract

The invention discloses a kind of drug for treating migraine, drug is made of Rhizoma Chuanxiong, uncaria, the root of Dahurain angelica, radix paeoniae rubra, stiff silkworm, toast scorpio, mulberry leaf, chrysanthemum powder, peppermint extracting solution, asarum, Rhizoma Et Radix Notopterygii, Rhizoma Gastrodiae, the shell of seaear, Prunella vulgaris, radix rehmanniae preparata, matrimony vine, Radix Astragali, Radix Angelicae Sinensis and safflower.The present invention adds mulberry leaf in formula, chrysanthemum powder and peppermint extracting solution, the headache syndromes caused by wind-heat can be mitigated, asarum and Rhizoma Et Radix Notopterygii are added in formula, the headache syndromes caused by chill can be mitigated, Rhizoma Gastrodiae is added in formula, the shell of seaear and Prunella vulgaris, the headache syndromes caused by liver-yang can be mitigated, radix rehmanniae preparata and matrimony vine are added in formula, the headache syndromes caused by the deficiency of liver-yin and kidney-yin can be mitigated, Radix Astragali and Radix Angelicae Sinensis are added in formula, the headache syndromes caused by deficiency of qi and blood can be mitigated, safflower is added in formula simultaneously, the headache syndromes caused by hemostasis can be mitigated.

Description

A kind of drug for treating migraine
Technical field
The present invention relates to pharmaceutical technology field, specially a kind of drug for treating migraine.
Background technology
Migraine is clinical most common primary headaches type, clinical based on ictal middle severe, beating sample headache It shows, headache is mostly inclined side, generally continues 4~72 hours, can be with Nausea and vomiting, light, Sound stimulat or daily routines Headache is aggravated, quiet environment, rest can alleviate headache, and migraine is a kind of common chronic forms vascular illness, a lot of diseases In children and puberty, the young and middle-aged phase reaches onset peak, and women is common, and men and women's Proportion of patients is about 1: 2~3, illness in crowd Rate is 5~10%, often there is genetic background, and since migraine is caused by several factors, and existing migraine remedy can not expire Foot treats migraine caused by different factors, causes therapeutic effect undesirable, for this purpose, it is proposed that a kind for the treatment of inclined head The drug of pain.
Invention content
The purpose of the present invention is to provide a kind of drugs for treating migraine, to solve mentioned above in the background art ask Topic.
To achieve the above object, the present invention provides the following technical solutions：A kind of drug for treating migraine, drug is by river Rhizome of chuanxiong, uncaria, the root of Dahurain angelica, radix paeoniae rubra, stiff silkworm, toast scorpio, mulberry leaf, chrysanthemum powder, peppermint extracting solution, asarum, Rhizoma Et Radix Notopterygii, Rhizoma Gastrodiae, the shell of seaear, summer Withered grass, radix rehmanniae preparata, matrimony vine, Radix Astragali, Radix Angelicae Sinensis and safflower composition, ingredients by weight are：Rhizoma Chuanxiong 30g；Uncaria 15g；Root of Dahurain angelica 30g；It is red Chinese herbaceous peony 10g；Stiff silkworm 10g；Process scorpio 9g；Mulberry leaf 40g；Chrysanthemum powder 30g；Peppermint extracting solution 10g；Asarum 10g；Rhizoma Et Radix Notopterygii 10g；Rhizoma Gastrodiae 10g；Shell of seaear 10g；Prunella vulgaris 10g；Radix rehmanniae preparata 10g；Matrimony vine 15g；Radix Astragali 20g；Radix Angelicae Sinensis 8g；Safflower 8g.
Preferably, the peppermint extracting solution is made of base oil, Peppermint essential oil, borneol essential oil and sweet orange oil, weight Percentage is：Base oil 25%~35%；Peppermint essential oil 30%~40%；Borneol essential oil 20%~30%；Sweet orange oil 15% ~25%.
Preferably, the chrysanthemum powder is made of chrysanthemum seed meal, pollen powder of chrysanthemun flower, chrysanthemum extract and chrysanthemum root powder, and its Weight percent is：Chrysanthemum seed meal 15%；Pollen powder of chrysanthemun flower 15%；Chrysanthemum extract 30%；Chrysanthemum root powder 30%.
Preferably, preparation process includes the following steps：
A, impurity is removed after being mixed by ingredients by weight except each raw material of peppermint extracting solution and in trash extraction box；
B, the raw material after removal of impurities is put into and carries out drying and processing in drying box；
C, the raw material after drying is crushed into processing；
D, the mixture after crushing is screened by the sieve of 80 molybdenums, and underproof raw material is reapposed over pulverizer Interior carry out separating twice, until its qualification；
E, the distilled water of the peppermint extracting solution and 0.3~0.5 times of dispensing summation of ingredients by weight is added in the powder after screening, mixes Close stirring；
F, the raw material after stirring is put into mold, and is pressed into pill.
G, it is packed after being processed by shot blasting to pill.
Preferably, the drying temperature in the step B is 60~80 DEG C, and drying time is 2.5~3.5h.
Preferably, the mixing time in the step E is 2~3h.
Compared with prior art, beneficial effects of the present invention are as follows：
The present invention adds mulberry leaf, chrysanthemum powder and peppermint extracting solution in formula, can mitigate the headache syndromes caused by wind-heat, Asarum and Rhizoma Et Radix Notopterygii are added in formula, can mitigate the headache syndromes caused by chill, add Rhizoma Gastrodiae, Shi Jue in formula Bright and Prunella vulgaris can mitigate the headache syndromes caused by liver-yang, add radix rehmanniae preparata and matrimony vine in formula, can mitigate because of liver kidney Headache syndromes caused by the deficiency of Yin, add Radix Astragali and Radix Angelicae Sinensis in formula, can mitigate the headache caused by deficiency of qi and blood Shape, while safflower is added in formula, the headache syndromes caused by hemostasis can be mitigated.
Description of the drawings
Fig. 1 is inventive formulation table schematic diagram.
Specific implementation mode
Following will be combined with the drawings in the embodiments of the present invention, and technical solution in the embodiment of the present invention carries out clear, complete Site preparation describes, it is clear that described embodiments are only a part of the embodiments of the present invention, instead of all the embodiments.It is based on Embodiment in the present invention, it is obtained by those of ordinary skill in the art without making creative efforts every other Embodiment shall fall within the protection scope of the present invention.
Referring to Fig. 1, a kind of drug for treating migraine, drug by Rhizoma Chuanxiong, uncaria, the root of Dahurain angelica, radix paeoniae rubra, stiff silkworm, toast scorpio, Mulberry leaf, chrysanthemum powder, peppermint extracting solution, asarum, Rhizoma Et Radix Notopterygii, Rhizoma Gastrodiae, the shell of seaear, Prunella vulgaris, radix rehmanniae preparata, matrimony vine, Radix Astragali, Radix Angelicae Sinensis and safranine Flower composition, ingredients by weight are：Rhizoma Chuanxiong 30g；Uncaria 15g；Root of Dahurain angelica 30g；Radix paeoniae rubra 10g；Stiff silkworm 10g；Process scorpio 9g；Mulberry leaf 40g； Chrysanthemum powder 30g；Peppermint extracting solution 10g；Asarum 10g；Rhizoma Et Radix Notopterygii 10g；Rhizoma Gastrodiae 10g；Shell of seaear 10g；Prunella vulgaris 10g；Radix rehmanniae preparata 10g； Matrimony vine 15g；Radix Astragali 20g；Radix Angelicae Sinensis 8g；Safflower 8g.
Peppermint extracting solution is made of base oil, Peppermint essential oil, borneol essential oil and sweet orange oil, and weight percent is：Base Plinth oil 25%~35%；Peppermint essential oil 30%~40%；Borneol essential oil 20%~30%；Sweet orange oil 15%~25%.
Chrysanthemum powder is made of chrysanthemum seed meal, pollen powder of chrysanthemun flower, chrysanthemum extract and chrysanthemum root powder, and its weight percent For：Chrysanthemum seed meal 15%；Pollen powder of chrysanthemun flower 15%；Chrysanthemum extract 30%；Chrysanthemum root powder 30%.
Its preparation process includes the following steps：
A, impurity is removed after being mixed by ingredients by weight except each raw material of peppermint extracting solution and in trash extraction box；
B, the raw material after removal of impurities is put into and carries out drying and processing in drying box；
C, the raw material after drying is crushed into processing；
D, the mixture after crushing is screened by the sieve of 80 molybdenums, and underproof raw material is reapposed over pulverizer Interior carry out separating twice, until its qualification；
E, the distilled water of the peppermint extracting solution and 0.3~0.5 times of dispensing summation of ingredients by weight is added in the powder after screening, mixes Close stirring；
F, the raw material after stirring is put into mold, and is pressed into pill.
G, it is packed after being processed by shot blasting to pill.
Drying temperature in step B is 60~80 DEG C, and drying time is 2.5~3.5h.
Mixing time in step E is 2~3h.
In use, adding mulberry leaf, chrysanthemum powder and peppermint extracting solution in formula, it can mitigate and have a headache caused by wind-heat Symptom adds asarum and Rhizoma Et Radix Notopterygii in formula, can mitigate the headache syndromes caused by chill, add day in formula Fiber crops, the shell of seaear and Prunella vulgaris, can mitigate the headache syndromes caused by liver-yang, add radix rehmanniae preparata and matrimony vine in formula, can subtract The gently headache syndromes caused by the deficiency of liver-yin and kidney-yin, add Radix Astragali and Radix Angelicae Sinensis in formula, and can mitigate causes because of deficiency of qi and blood Headache syndromes, while adding safflower in formula, the headache syndromes caused by hemostasis can be mitigated.
It although an embodiment of the present invention has been shown and described, for the ordinary skill in the art, can be with Understanding without departing from the principles and spirit of the present invention can carry out these embodiments a variety of variations, modification, replace And modification, the scope of the present invention is defined by the appended.

Claims (6)

1. a kind of drug for treating migraine, it is characterised in that：Drug by Rhizoma Chuanxiong, uncaria, the root of Dahurain angelica, radix paeoniae rubra, stiff silkworm, toast scorpio, Mulberry leaf, chrysanthemum powder, peppermint extracting solution, asarum, Rhizoma Et Radix Notopterygii, Rhizoma Gastrodiae, the shell of seaear, Prunella vulgaris, radix rehmanniae preparata, matrimony vine, Radix Astragali, Radix Angelicae Sinensis and safranine Flower composition, ingredients by weight are：Rhizoma Chuanxiong 30g；Uncaria 15g；Root of Dahurain angelica 30g；Radix paeoniae rubra 10g；Stiff silkworm 10g；Process scorpio 9g；Mulberry leaf 40g； Chrysanthemum powder 30g；Peppermint extracting solution 10g；Asarum 10g；Rhizoma Et Radix Notopterygii 10g；Rhizoma Gastrodiae 10g；Shell of seaear 10g；Prunella vulgaris 10g；Radix rehmanniae preparata 10g； Matrimony vine 15g；Radix Astragali 20g；Radix Angelicae Sinensis 8g；Safflower 8g.
2. a kind of drug for treating migraine according to claim 1, it is characterised in that：The peppermint extracting solution is by basis Oil, Peppermint essential oil, borneol essential oil and sweet orange oil composition, weight percent are：Base oil 25%~35%；Peppermint essential oil 30%~40%；Borneol essential oil 20%~30%；Sweet orange oil 15%~25%.
3. a kind of drug for treating migraine according to claim 1, it is characterised in that：The chrysanthemum powder is by chrysanthemum seed Powder, pollen powder of chrysanthemun flower, chrysanthemum extract and chrysanthemum root powder composition, and its weight percent is：Chrysanthemum seed meal 15%；Pollen powder of chrysanthemun flower 15%；Chrysanthemum extract 30%；Chrysanthemum root powder 30%.
4. a kind of drug for treating migraine according to claim 1, it is characterised in that：Its preparation process includes following step Suddenly：
A, impurity is removed after being mixed by ingredients by weight except each raw material of peppermint extracting solution and in trash extraction box；
B, the raw material after removal of impurities is put into and carries out drying and processing in drying box；
C, the raw material after drying is crushed into processing；
D, the mixture after crushing is screened by the sieve of 80 molybdenums, and underproof raw material is reapposed over pulverizer Interior carry out separating twice, until its qualification；
E, the distilled water of the peppermint extracting solution and 0.3~0.5 times of dispensing summation of ingredients by weight is added in the powder after screening, mixes Close stirring；
F, the raw material after stirring is put into mold, and is pressed into pill.
G, it is packed after being processed by shot blasting to pill.
5. a kind of drug for treating migraine according to claim 4, it is characterised in that：Drying temperature in the step B Degree is 60~80 DEG C, and drying time is 2.5~3.5h.
6. a kind of drug for treating migraine according to claim 4, it is characterised in that：When stirring in the step E Between be 2~3h.
CN201810193745.2A 2018-03-09 2018-03-09 A kind of drug for treating migraine Withdrawn CN108452192A (en)

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Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107568443A (en) * 2017-10-23 2018-01-12 何正国 A kind of gel fish grain and preparation method thereof

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107568443A (en) * 2017-10-23 2018-01-12 何正国 A kind of gel fish grain and preparation method thereof

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
全亚萍: "天宁饮治疗偏头痛58例临床研究", 《江苏中医药》 *

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Application publication date: 20180828