CN108434329A - 一种中药制剂配方 - Google Patents

一种中药制剂配方 Download PDF

Info

Publication number
CN108434329A
CN108434329A CN201810536861.XA CN201810536861A CN108434329A CN 108434329 A CN108434329 A CN 108434329A CN 201810536861 A CN201810536861 A CN 201810536861A CN 108434329 A CN108434329 A CN 108434329A
Authority
CN
China
Prior art keywords
grams
raw material
formula
water
radix
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
CN201810536861.XA
Other languages
English (en)
Inventor
李红光
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to CN201810536861.XA priority Critical patent/CN108434329A/zh
Publication of CN108434329A publication Critical patent/CN108434329A/zh
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/34—Campanulaceae (Bellflower family)
    • A61K36/344—Codonopsis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06—Fungi, e.g. yeasts
    • A61K36/07—Basidiomycota, e.g. Cryptococcus
    • A61K36/076—Poria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A61K36/258—Panax (ginseng)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/57—Magnoliaceae (Magnolia family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/72—Rhamnaceae (Buckthorn family), e.g. buckthorn, chewstick or umbrella-tree
    • A61K36/725—Ziziphus, e.g. jujube
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/79—Schisandraceae (Schisandra family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/81—Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
    • A61K36/815—Lycium (desert-thorn)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8968—Ophiopogon (Lilyturf)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8969—Polygonatum (Solomon's seal)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50—Methods involving additional extraction steps
    • A61K2236/53—Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization

Landscapes

  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Biotechnology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Anesthesiology (AREA)
  • Molecular Biology (AREA)
  • Nutrition Science (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

一种中药制剂配方，涉及药物配方加工技术领域。其特征是：所述配方包括水提取原料和直接粉碎原料，所述水提取原料按如下质量配比：党参300‑500克，玉竹100‑300克，麦冬300‑500克，枸杞子300‑500克，西洋参100‑200克，酸枣仁300‑500克；所述直接粉碎原料按如下质量配比：茯神200‑350克，五味子100‑300克，白砂糖100‑150克。本发明的有益效果是：配方采用较为多见的中草药材作为原料配制制剂，制备工艺简单，对人体无副作用，生产成本低，而且产品具有补肾、益气养阴、安神的作用及消除顽固性失眠的症状。

Description

一种中药制剂配方
技术领域
本发明属于药物配方领域，尤其涉及一种中药制剂配方。
背景技术
失眠即睡眠失常，临床症状表现为入睡困难，断断续续不连贯，过早地醒来，醒后不能再继续入睡，有睡眠不足，全身乏力，倦怠的感觉。失眠是临床常见病症之一，虽不属于危重疾病，但妨碍人们正常生活、工作、学习和健康，且能加重或诱发心悸、胸痹、眩晕、头痛及中风等病症。顽固性的失眠，不仅给病人带来长期的痛苦，甚至形成对安眠药物的长期依赖，且长期服用安眠药物又可引起医源性疾病。目前用于治疗顽固性失眠的中药制剂较少且药物的成本较高，对顽固性失眠的疗效有限，无法完全康复。
发明内容
为了克服如上所述的问题，本发明提供一种中药制剂配方，以弥补其不足。
本发明解决其技术问题所采取的技术方案是：一种中药制剂配方，其特征在于，所述配方包括水提取原料和直接粉碎原料，所述水提取原料按如下质量配比：党参300-500克，玉竹100-300克，麦冬300-500克，枸杞子300-500克，西洋参100-200克，酸枣仁300-500克；所述直接粉碎原料按如下质量配比：茯神200-350克，五味子100-300克，白砂糖100-150克。
先将上述所有水提取原料混合后加入8倍原料重量的水浸泡0.5-1小时后，煎煮2-3个小时，倒出药液，再加入8倍原料重量的水煎煮1-2小时，倒出药液，将两次煎煮的药液混合过滤；将过滤后的滤液浓缩至温度为80℃，密度为1.15-1.20千克/立方米，并冷却至20-30℃，加乙醇至含醇量达75％后搅拌、静置24小时，取出上清液，得到沉淀物；将沉淀物通过压缩形成膏状；将上述直接粉碎原料经混合后粉碎，过120目筛，与膏状沉淀物混合搅匀后制成颗粒；将颗粒干燥至含水量为0.5-2％，即可制成成品。
上述原料的功效作用是：党参：补中益气；玉竹：养阴润燥，生津止渴；麦冬：润肺清心，养胃生津；枸杞子：补肾益精，养肝明目；西洋参：清肺养阴，养胃生津；酸枣仁：补肝益胆，宁心安神；茯神：宁心安神；五味子：敛肺滋肾，生津涩精。
本发明的有益效果是：配方采用较为多见的中草药材作为原料配制制剂，制备工艺简单，对人体无副作用，生产成本低，而且产品具有补肾、益气养阴、安神的作用及消除顽固性失眠的症状。
具体实施方式
下面结合具体实施例，进一步阐述本发明。
实施例1
一种中药制剂配方，其特征在于，所述配方包括水提取原料和直接粉碎原料，所述水提取原料按如下质量配比：党参300克，玉竹100克，麦冬300克，枸杞子300克，西洋参100克，酸枣仁300克；所述直接粉碎原料按如下质量配比：茯神200克，五味子100克，白砂糖100克。先将上述所有水提取原料混合后加入8倍原料重量的水浸泡0.5-1小时后，煎煮2-3个小时，倒出药液，再加入8倍原料重量的水煎煮1-2小时，倒出药液，将两次煎煮的药液混合过滤；将过滤后的滤液浓缩至温度为80℃，密度为1.15-1.20千克/立方米，并冷却至20-30℃，加乙醇至含醇量达75％后搅拌、静置24小时，取出上清液，得到沉淀物；将沉淀物通过压缩形成膏状；将上述直接粉碎原料经混合后粉碎，过120目筛，与膏状沉淀物混合搅匀后制成颗粒；将颗粒干燥至含水量为0.5-2％，即可制成成品。
实施例2
一种中药制剂配方，其特征在于，所述配方包括水提取原料和直接粉碎原料，所述水提取原料按如下质量配比：党参400克，玉竹200克，麦冬400克，枸杞子400克，西洋参150克，酸枣仁400克；所述直接粉碎原料按如下质量配比：茯神275克，五味子200克，白砂糖125克。先将上述所有水提取原料混合后加入8倍原料重量的水浸泡0.5-1小时后，煎煮2-3个小时，倒出药液，再加入8倍原料重量的水煎煮1-2小时，倒出药液，将两次煎煮的药液混合过滤；将过滤后的滤液浓缩至温度为80℃，密度为1.15-1.20千克/立方米，并冷却至20-30℃，加乙醇至含醇量达75％后搅拌、静置24小时，取出上清液，得到沉淀物；将沉淀物通过压缩形成膏状；将上述直接粉碎原料经混合后粉碎，过120目筛，与膏状沉淀物混合搅匀后制成颗粒；将颗粒干燥至含水量为0.5-2％，即可制成成品。
实施例3
一种中药制剂配方，其特征在于，所述配方包括水提取原料和直接粉碎原料，所述水提取原料按如下质量配比：党参500克，玉竹300克，麦冬500克，枸杞子500克，西洋参200克，酸枣仁500克；所述直接粉碎原料按如下质量配比：茯神350克，五味子300克，白砂糖150克。先将上述所有水提取原料混合后加入8倍原料重量的水浸泡0.5-1小时后，煎煮2-3个小时，倒出药液，再加入8倍原料重量的水煎煮1-2小时，倒出药液，将两次煎煮的药液混合过滤；将过滤后的滤液浓缩至温度为80℃，密度为1.15-1.20千克/立方米，并冷却至20-30℃，加乙醇至含醇量达75％后搅拌、静置24小时，取出上清液，得到沉淀物；将沉淀物通过压缩形成膏状；将上述直接粉碎原料经混合后粉碎，过120目筛，与膏状沉淀物混合搅匀后制成颗粒；将颗粒干燥至含水量为0.5-2％，即可制成成品。

Claims (5)

1.一种中药制剂配方，其特征在于，所述配方包括水提取原料和直接粉碎原料，所述水提取原料按如下质量配比：党参300-500克，玉竹100-300克，麦冬300-500克，枸杞子300-500克，西洋参100-200克，酸枣仁300-500克；所述直接粉碎原料按如下质量配比：茯神200-350克，五味子100-300克，白砂糖100-150克。
2.如权利要求1所述的配方，其特征在于，所述水提取原料混合后用水浸泡、煎煮及过滤，将过滤后的滤液浓缩至温度为80℃，密度为1.15-1.20千克/立方米，并冷却至20-30℃，加乙醇至含醇量达75％后搅拌、静置，取出上清液，得到沉淀物。
3.如权利要求2所述的配方，其特征在于，所述沉淀物通过压缩形成膏状。
4.如权利要求1所述的配方，其特征在于，所述直接粉碎原料经混合后粉碎，过120目筛，与权利要求3所述膏状的沉淀物混合搅匀后制成颗粒。
5.如权利要求4所述的配方，其特征在于，所述颗粒干燥至含水量为0.5-2％，即可制成成品。
CN201810536861.XA 2018-05-21 2018-05-21 一种中药制剂配方 Withdrawn CN108434329A (zh)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201810536861.XA CN108434329A (zh) 2018-05-21 2018-05-21 一种中药制剂配方

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201810536861.XA CN108434329A (zh) 2018-05-21 2018-05-21 一种中药制剂配方

Publications (1)

Publication Number Publication Date
CN108434329A true CN108434329A (zh) 2018-08-24

Family

ID=63205736

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201810536861.XA Withdrawn CN108434329A (zh) 2018-05-21 2018-05-21 一种中药制剂配方

Country Status (1)

Country Link
CN (1) CN108434329A (zh)

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1141780A (zh) * 1995-07-28 1997-02-05 周正义 一种人体净化剂
CN103142847A (zh) * 2013-01-22 2013-06-12 南宁市神明药物研究所有限责任公司 一种中药制剂配方
CN105596775A (zh) * 2015-11-24 2016-05-25 薛学明 一种增强抵抗力的药物及其制备方法
CN107744510A (zh) * 2017-10-25 2018-03-02 广东罗浮山国药股份有限公司 一种微丸型配方颗粒的制备方法
CN107875393A (zh) * 2016-09-30 2018-04-06 深圳市傲来大健康产业有限公司 一种含片矫味剂及其制备方法

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1141780A (zh) * 1995-07-28 1997-02-05 周正义 一种人体净化剂
CN103142847A (zh) * 2013-01-22 2013-06-12 南宁市神明药物研究所有限责任公司 一种中药制剂配方
CN105596775A (zh) * 2015-11-24 2016-05-25 薛学明 一种增强抵抗力的药物及其制备方法
CN107875393A (zh) * 2016-09-30 2018-04-06 深圳市傲来大健康产业有限公司 一种含片矫味剂及其制备方法
CN107744510A (zh) * 2017-10-25 2018-03-02 广东罗浮山国药股份有限公司 一种微丸型配方颗粒的制备方法

Similar Documents

Publication Publication Date Title
CN101530548B (zh) 一种具有多种保健功能的组合物及其制备方法
CN101653553A (zh) 一种益心安神颗粒
CN102100856A (zh) 一种治疗支气管哮喘纳米中药及制备技术
CN103656351A (zh) 一种润肠通便中药胶囊及其制备方法
CN102138655A (zh) 桂圆补血膏新型配方及其制作方法
CN100540041C (zh) 一种增智健脑制剂及其制备方法
CN1519006A (zh) 一种治疗脾虚食滞引起的小儿厌食病症的中成药
CN103330785B (zh) 一种益气养血、滋补肝肾的药物的制备方法
CN102415471B (zh) 健脾消食提神无糖口香糖
CN103349708B (zh) 一种益气养血、滋补肝肾的药物及其制备方法
CN109157624A (zh) 一种补脾养胃抗衰老的营养药物
CN108434329A (zh) 一种中药制剂配方
CN103784884A (zh) 一种治疗心肝火旺型失眠的中药组合物
CN103877325A (zh) 一种治疗心脑血管病的中药组合物及其制备方法
CN103652906B (zh) 一种养阴生津生地黄咀嚼片及制备方法
CN106578262A (zh) 一种袋泡杜仲茶颗粒及其制备方法
CN106334065A (zh) 一种治疗妇科疾病及具有美容作用的药食两用中药配方及生产工艺
CN106620475B (zh) 一种防治糖尿病认知障碍的中药组合物及制备方法
CN105056170A (zh) 一种中药组合物在制备治疗急性胃炎药物中的用途
CN103142847B (zh) 一种中药制剂
CN102362930A (zh) 一种祛除黄褐斑的中药口服液及其制备工艺
CN101473937A (zh) 一种红茶保健食品及其制备方法
CN105981851A (zh) 一种太子参颗粒茶及其制备方法
CN106606587A (zh) 一种养血安神药物组合物
CN102716331B (zh) 治疗眩晕的熟地黄中药制剂及制备方法

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
WW01 Invention patent application withdrawn after publication
WW01 Invention patent application withdrawn after publication

Application publication date: 20180824