CN108434244A - A kind of application of mulberry bavin extracting solution in anti-bacteria and anti-virus - Google Patents
A kind of application of mulberry bavin extracting solution in anti-bacteria and anti-virus Download PDFInfo
- Publication number
- CN108434244A CN108434244A CN201810505647.8A CN201810505647A CN108434244A CN 108434244 A CN108434244 A CN 108434244A CN 201810505647 A CN201810505647 A CN 201810505647A CN 108434244 A CN108434244 A CN 108434244A
- Authority
- CN
- China
- Prior art keywords
- parts
- mulberry
- extracting solution
- bavin
- radix
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/60—Moraceae (Mulberry family), e.g. breadfruit or fig
- A61K36/605—Morus (mulberry)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/34—Campanulaceae (Bellflower family)
- A61K36/346—Platycodon
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/35—Caprifoliaceae (Honeysuckle family)
- A61K36/355—Lonicera (honeysuckle)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/484—Glycyrrhiza (licorice)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/534—Mentha (mint)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/539—Scutellaria (skullcap)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/80—Scrophulariaceae (Figwort family)
- A61K36/804—Rehmannia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/80—Scrophulariaceae (Figwort family)
- A61K36/808—Scrophularia (figwort)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/10—Preparation or pretreatment of starting material
- A61K2236/13—Preparation or pretreatment of starting material involving cleaning, e.g. washing or peeling
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
Abstract
The invention discloses a kind of application of mulberry bavin extracting solution in anti-bacteria and anti-virus, the drug ingedient includes following substance, mulberry bavin extracting solution, Flos Lonicerae extractive solution, radix scutellariae extracting solution, radix scrophulariae, campanulaceae, glutinous rehmannia, Radix Glycyrrhizae, peppermint, xylitol, malic acid.The present invention is Chinese traditional medicine composition drug, and pharmacological property is mild, can efficiently be extracted to Chinese medicines such as mulberry bavin, honeysuckle and radix scutellariaes, and uniform to mix, use easy to produce, simple operation of the present invention is highly practical, convenient for promoting the use of.
Description
Technical field
The present invention relates to plant extract applied technical field, specially a kind of mulberry bavin extracting solution answering in anti-bacteria and anti-virus
With.
Background technology
Mulberry tree tree body is rich in serum, bark yellowish-brown.Leaf is oval to wide oval, and end of blade point, phyllopodium is round or shallow heart-shaped,
There is rough sawn tooth at edge, there is irregular division sometimes.Blade face is hairless, glossy, has thin hair on blade back arteries and veins.Dioecism, light,
Slightly shade tolerant when young.Warm and moist weather is liked, is resisted cold.Drought-resistant, water-fast wet ability is strong.The spray of mulberry tree, the end of spring and the beginning of summer harvesting.Its
It is bitter in taste flat, enter Liver Channel partially, work(arrogates to oneself wind-damp dispelling, degrading the channel, sharp joint, row aqueous vapor.It is chiefly used in treatment arthralgia pain due to rheumatism, four limbs are arrested
Contraction, oedema, body such as are itched at the cards, are arrogated to oneself especially and are treated upper limb numbness pain.Can decoction or cream it is for oral administration, also can (drugs) to be decocted and used as a lotion.
For child due to skin delicacy, autoimmunity is weaker, is easier to cause to infect after skin comes to harm, if obtaining not
Body face can be caused to fester to timely processing, if being handled wound by drugs such as antibiotic, on the one hand to child's skin
It stimulates larger, is unsuitable for children's use, while antibiotic these drugs are used for a long time, virus can form resistance to it, be unfavorable for
Child's grows up strong and sturdy, it is therefore desirable to which a kind of pharmacological property is mild, and suitable for the antibacterial and antiviral drug that child uses, and mulberry tree is extracted
Liquid pharmacological property is mild, is traditional Chinese medicinal material, is suitable for using, therefore the present invention provides a kind of new technical solution, to solve this
One problem.
Invention content
The purpose of the present invention is to provide a kind of application of mulberry bavin extracting solution in anti-bacteria and anti-virus, to solve above-mentioned background
The problem of being proposed in technology.
To achieve the above object, the present invention provides the following technical solutions：A kind of mulberry bavin extracting solution is in anti-bacteria and anti-virus
Include following substance using, the drug ingedient, mulberry bavin extracting solution, Flos Lonicerae extractive solution, radix scutellariae extracting solution, radix scrophulariae, campanulaceae,
Huang, Radix Glycyrrhizae, peppermint, xylitol, malic acid.
As a preferred technical solution of the present invention, described its weight proportion of drug each component is as follows：Mulberry bavin extracting solution
30-40 parts, 20-35 parts of Flos Lonicerae extractive solution, 15-25 parts of radix scutellariae extracting solution, 5-10 parts of radix scrophulariae, 8-13 parts of campanulaceae, glutinous rehmannia 1-5
Part, 5-10 parts of Radix Glycyrrhizae, 5-10 parts of peppermint, 1-5 parts of xylitol, 1-3 parts of malic acid.
As a preferred technical solution of the present invention, the mulberry bavin extracting solution includes following extraction process：
S1, pretreatment：Mulberry bavin is cleaned in high pressure water, while being carried out dehydrating in high temperature pressure pot；
S2, distillation extraction：Get Sang Chai will be cleaned to be placed in distillation still, under 160-280 DEG C, 0.2-0.5mpa pressure conditions into
Row distills to obtain volatilization gas, it is passed through in distillation still again, the bottom material mulberry bavin of one third is taken out, new Sang Chai is added,
180-310 DEG C, pressure control is distilled again under conditions of 0.2-0.6mpa, obtains volatilization gas；
S3, condensation：Volatilization gas in S2 is passed through condenser to cool down, while being carried out at atomization in ultrasonic ultrasonic delay line memory
Reason, get Sang Chai extracting solutions.
As a preferred technical solution of the present invention, the Flos Lonicerae extractive solution, radix scutellariae extracting solution extraction process are as follows：
S1, cleaning segment：Honeysuckle and radix scutellariae are cleaned, after drying surface moisture, by honeysuckle and Huang in segment cutter
A kind of reed mentioned in ancient books carries out segment, and size length is 0.5-1CM, and stir-frying dehydration is carried out at 40-80 DEG C, and pressure is controlled in 0.3-0.5mpa；
S2, extraction：Honeysuckle in S1 and radix scutellariae are respectively placed in different distillation stills, to gold and silver under 150-180 DEG C of environment
Flower carries out distillation processing, and pressure control is in 0.4-0.6mpa, distillation time 0.5-1 hour, by escaping gas discharge and from
The bottom of radix scutellariae distillation still is passed through, and distillation processing, reaction time are carried out to radix scutellariae under 180-230 DEG C, 0.3-0.6mpa environment
1-1.5 hours, obtain mixed gas.
S3, condensation：Mixed gas in S2 is passed through cooling treatment in condenser, and by gained liquid and water through 1：
1.5 are mixed, and atomization process is carried out in ultrasonic ultrasonic delay line memory, obtain honeysuckle radix scutellariae mixed extract.
As a preferred technical solution of the present invention, radix scrophulariae, campanulaceae, glutinous rehmannia, Radix Glycyrrhizae, peppermint are carried through ethyl alcohol
It takes, obtains mixing Chinese medicine extract, and be placed in boiler and heated with mulberry bavin extracting solution and honeysuckle radix scutellariae mixed extract
Tanning, it is primary every 5min stirrings, xylitol and malic acid are added thereto after boiling time 10-20min, continues to boil 20-
30min, cool to obtain finished product.
As a preferred technical solution of the present invention, paraffin removal step can be added in the step S1, to remove mulberry
The wax ingredient on surface.
As a preferred technical solution of the present invention, described its weight proportion of drug each component is as follows：Mulberry bavin extracting solution
30 parts, 35 parts of Flos Lonicerae extractive solution, 15 parts of radix scutellariae extracting solution, 10 parts of radix scrophulariae, 8 parts of campanulaceae, 5 parts of glutinous rehmannia, 5 parts of Radix Glycyrrhizae, peppermint 10
Part, 1 part of xylitol, 3 parts of malic acid.
As a preferred technical solution of the present invention, described its weight proportion of drug each component is as follows：Mulberry bavin extracting solution
40 parts, 20 parts of Flos Lonicerae extractive solution, 25 parts of radix scutellariae extracting solution, 5 parts of radix scrophulariae, 13 parts of campanulaceae, 1 part of glutinous rehmannia, 10 parts of Radix Glycyrrhizae, peppermint 5
Part, 5 parts of xylitol, 1 part of malic acid.
As a preferred technical solution of the present invention, described its weight proportion of drug each component is as follows：Mulberry bavin extracting solution
35 parts, 28 parts of Flos Lonicerae extractive solution, 20 parts of radix scutellariae extracting solution, 8 parts of radix scrophulariae, 10 parts of campanulaceae, 3 parts of glutinous rehmannia, 7 parts of Radix Glycyrrhizae, peppermint 8
Part, 3 parts of xylitol, 2 parts of malic acid.
Compared with prior art, the beneficial effects of the invention are as follows：Conventional medicament is larger to child's skin irritatin, easy tos produce
Resistance is unfavorable for child's use, and the spray of mulberry tree is bitter in taste flat, enters Liver Channel partially, and work(arrogates to oneself wind-damp dispelling, degrading the channel, sharp joint,
Row aqueous vapor.It is chiefly used in treating arthralgia pain due to rheumatism, the cards such as spasm of limbs, oedema, body are itched, arrogates to oneself especially and treat upper limb numbness pain.The branch of mulberry tree
After burning, juice can be leached, name mulberry drips,《Compendium of Materia Medica》Equal books carry it, and to treat " strong wind sore scabies ", lockjaw, children's body face rotten
The diseases such as sore, pharmacological property is mild, and larger stimulation will not be caused to the skin of child, is suitble to use, while the big multi-flavor of Chinese medicine itself
Xylitol and malic acid is added to improve mouthfeel in hardship wherein, and the present invention is Chinese traditional medicine composition drug, and pharmacological property is mild, can to mulberry bavin,
The Chinese medicines such as honeysuckle and radix scutellariae are efficiently extracted, uniform to mix, use easy to produce, and simple operation of the present invention is practical
Property is strong, convenient for promoting the use of.
Specific implementation mode
Below in conjunction with the embodiment of the present invention, technical scheme in the embodiment of the invention is clearly and completely described,
Obviously, described embodiments are only a part of the embodiments of the present invention, instead of all the embodiments.Based in the present invention
Embodiment, every other embodiment obtained by those of ordinary skill in the art without making creative efforts, all
Belong to the scope of protection of the invention.
Embodiment 1
A kind of application of mulberry bavin extracting solution in anti-bacteria and anti-virus, its weight proportion of drug each component are as follows：Drug each component its
Weight proportion is as follows：30 parts of mulberry bavin extracting solution, 35 parts of Flos Lonicerae extractive solution, 15 parts of radix scutellariae extracting solution, 10 parts of radix scrophulariae, 8 parts of campanulaceae,
5 parts of glutinous rehmannia, 5 parts of Radix Glycyrrhizae, 10 parts of peppermint, 1 part of xylitol, 3 parts of malic acid.
Wherein mulberry bavin extracting solution includes following extraction process：
S1, pretreatment：Mulberry bavin is cleaned in high pressure water, while being carried out dehydrating in high temperature pressure pot；
S2, distillation extraction：Get Sang Chai will be cleaned to be placed in distillation still, under 160-280 DEG C, 0.2-0.5mpa pressure conditions into
Row distills to obtain volatilization gas, it is passed through in distillation still again, the bottom material mulberry bavin of one third is taken out, new Sang Chai is added,
180-310 DEG C, pressure control is distilled again under conditions of 0.2-0.6mpa, obtains volatilization gas；
S3, condensation：Volatilization gas in S2 is passed through condenser to cool down, while being carried out at atomization in ultrasonic ultrasonic delay line memory
Reason, get Sang Chai extracting solutions.
Flos Lonicerae extractive solution, radix scutellariae extracting solution extraction process are as follows：
S1, cleaning segment：Honeysuckle and radix scutellariae are cleaned, after drying surface moisture, by honeysuckle and Huang in segment cutter
A kind of reed mentioned in ancient books carries out segment, and size length is 0.5-1CM, and stir-frying dehydration is carried out at 40-80 DEG C, and pressure is controlled in 0.3-0.5mpa；
S2, extraction：Honeysuckle in S1 and radix scutellariae are respectively placed in different distillation stills, to gold and silver under 150-180 DEG C of environment
Flower carries out distillation processing, and pressure control is in 0.4-0.6mpa, distillation time 0.5-1 hour, by escaping gas discharge and from
The bottom of radix scutellariae distillation still is passed through, and distillation processing, reaction time are carried out to radix scutellariae under 180-230 DEG C, 0.3-0.6mpa environment
1-1.5 hours, obtain mixed gas.
S3, condensation：Mixed gas in S2 is passed through cooling treatment in condenser, and by gained liquid and water through 1：
1.5 are mixed, and atomization process is carried out in ultrasonic ultrasonic delay line memory, obtain honeysuckle radix scutellariae mixed extract.
Radix scrophulariae, campanulaceae, glutinous rehmannia, Radix Glycyrrhizae, peppermint are extracted through ethyl alcohol, obtain mixing Chinese medicine extract, and and Sang Chaiti
Liquid and honeysuckle radix scutellariae mixed extract is taken to be placed in boiler and carry out heating tanning, it is primary every 5min stirrings, boil the time
Xylitol and malic acid is added after 10-20min thereto, continues to boil 20-30min, cool to obtain finished product.
Paraffin removal step can be added in step sl, to remove the wax ingredient on mulberry surface.
Embodiment 2
The present invention provides another embodiment, a kind of application of mulberry bavin extracting solution in anti-bacteria and anti-virus, its is heavy for drug each component
Amount proportioning is as follows：40 parts of mulberry bavin extracting solution, 20 parts of Flos Lonicerae extractive solution, 25 parts of radix scutellariae extracting solution, 5 parts of radix scrophulariae, 13 parts of campanulaceae,
1 part yellow, 10 parts of Radix Glycyrrhizae, 5 parts of peppermint, 5 parts of xylitol, 1 part of malic acid.
Embodiment 3
The present invention provides another embodiment, its weight proportion of drug each component is as follows：35 parts of mulberry bavin extracting solution, honeysuckle extraction
28 parts of liquid, 20 parts of radix scutellariae extracting solution, 8 parts of radix scrophulariae, 10 parts of campanulaceae, 3 parts of glutinous rehmannia, 7 parts of Radix Glycyrrhizae, 8 parts of peppermint, 3 parts of xylitol, apple
2 parts of acid.
The present invention is subjected to following Antiviral breeding：
Experiment condition
Control sample:Deionized water
Sample weight: 0.4g
Antibacterial experiment standard: ISO18184：2015
Strain:Influenza virus H1N1（ATCC A/PR/8/34, VR-1469）
Host cell:Canine kidney epidermal cell MDCK cells (ATCC CCL-34)
Inoculation time:25 DEG C 2 hours
The time is made in cell sense:37 DEG C of 5%,CO2 72 hours
2, experimental result
Remarks
Antiviral activity value (iso standard)=control sample virus infection valence-sample virus infects valence
Antiviral activity value (JIS standards)=Strain treating initial infection valence-sample virus infects valence
ISO: International standard organization
JIS: Japan Industry Standard
Judgment criteria:ISO, antiviral activity value>=2, there is antiviral property;Antiviral activity value>=3, have stronger disease-resistant
Cytotoxic activity JIS, antiviral activity value>=3, there is antiviral activity.
From the point of view of experimental result, the present invention has good effect in anti-virus aspect.
Conventional medicament is larger to child's skin irritatin, easy tos produce resistance, is unfavorable for child and uses, the spray of mulberry tree,
It is bitter in taste flat, enter Liver Channel partially, work(arrogates to oneself wind-damp dispelling, degrading the channel, sharp joint, row aqueous vapor.It is chiefly used in treatment arthralgia pain due to rheumatism, four limbs are arrested
Contraction, oedema, body such as are itched at the cards, are arrogated to oneself especially and are treated upper limb numbness pain.After the branch of mulberry tree is burnt, juice can be leached, name mulberry drips,《Herbal guiding principle
Mesh》Equal books, which carry it, can treat the diseases such as " strong wind sore scabies ", lockjaw, children's body face rotten sore, and pharmacological property is mild, will not be to the skin of child
Skin causes larger stimulation, is suitble to use, while the most bitter of Chinese medicine itself, and xylitol and apple are added wherein to improve mouthfeel
Tartaric acid.
The present invention is Chinese traditional medicine composition drug, and pharmacological property is mild, can efficiently be carried to Chinese medicines such as mulberry bavin, honeysuckle and radix scutellariaes
It takes, uniform to mix, use easy to produce, simple operation of the present invention is highly practical, convenient for promoting the use of.
It although an embodiment of the present invention has been shown and described, for the ordinary skill in the art, can be with
Understanding without departing from the principles and spirit of the present invention can carry out these embodiments a variety of variations, modification, replace
And modification, the scope of the present invention is defined by the appended.
Claims (9)
1. a kind of application of mulberry bavin extracting solution in anti-bacteria and anti-virus, it is characterised in that：The drug ingedient includes following substance,
Mulberry bavin extracting solution, Flos Lonicerae extractive solution, radix scutellariae extracting solution, radix scrophulariae, campanulaceae, glutinous rehmannia, Radix Glycyrrhizae, peppermint, xylitol, malic acid.
2. a kind of application of the mulberry bavin extracting solution according to claim 1 in anti-bacteria and anti-virus, it is characterised in that：The medicine
Its weight proportion of object each component is as follows：30-40 parts of mulberry bavin extracting solution, 20-35 parts of Flos Lonicerae extractive solution, radix scutellariae extracting solution 15-25
Part, 5-10 parts of radix scrophulariae, 8-13 parts of campanulaceae, 1-5 parts of glutinous rehmannia, 5-10 parts of Radix Glycyrrhizae, 5-10 parts of peppermint, 1-5 parts of xylitol, malic acid 1-
3 parts.
3. a kind of application of the mulberry bavin extracting solution according to claim 2 in anti-bacteria and anti-virus, it is characterised in that：The mulberry
Bavin extracting solution includes following extraction process：
S1, pretreatment：Mulberry bavin is cleaned in high pressure water, while being carried out dehydrating in high temperature pressure pot；
S2, distillation extraction：Get Sang Chai will be cleaned to be placed in distillation still, under 160-280 DEG C, 0.2-0.5mpa pressure conditions into
Row distills to obtain volatilization gas, it is passed through in distillation still again, the bottom material mulberry bavin of one third is taken out, new Sang Chai is added,
180-310 DEG C, pressure control is distilled again under conditions of 0.2-0.6mpa, obtains volatilization gas；
S3, condensation：Volatilization gas in S2 is passed through condenser to cool down, while being carried out at atomization in ultrasonic ultrasonic delay line memory
Reason, get Sang Chai extracting solutions.
4. a kind of application of the mulberry bavin extracting solution according to claim 2 in anti-bacteria and anti-virus, it is characterised in that：The gold
Honeysuckle flower extracting solution, radix scutellariae extracting solution extraction process are as follows：
S1, cleaning segment：Honeysuckle and radix scutellariae are cleaned, after drying surface moisture, by honeysuckle and Huang in segment cutter
A kind of reed mentioned in ancient books carries out segment, and size length is 0.5-1CM, and stir-frying dehydration is carried out at 40-80 DEG C, and pressure is controlled in 0.3-0.5mpa；
S2, extraction：Honeysuckle in S1 and radix scutellariae are respectively placed in different distillation stills, to gold and silver under 150-180 DEG C of environment
Flower carries out distillation processing, and pressure control is in 0.4-0.6mpa, distillation time 0.5-1 hour, by escaping gas discharge and from
The bottom of radix scutellariae distillation still is passed through, and distillation processing, reaction time are carried out to radix scutellariae under 180-230 DEG C, 0.3-0.6mpa environment
1-1.5 hours, obtain mixed gas；
S3, condensation：Mixed gas in S2 is passed through cooling treatment in condenser, and by gained liquid and water through 1：1.5 into
Row mixing, atomization process is carried out in ultrasonic ultrasonic delay line memory, obtains honeysuckle radix scutellariae mixed extract.
5. application of a kind of mulberry bavin extracting solution in anti-bacteria and anti-virus according to claim 1-4, it is characterised in that：It will be profound
Ginseng, campanulaceae, glutinous rehmannia, Radix Glycyrrhizae, peppermint extract through ethyl alcohol, obtain mixing Chinese medicine extract, and with mulberry bavin extracting solution and honeysuckle
Radix scutellariae mixed extract, which is placed in boiler, carries out heating tanning, and primary every 5min stirrings, tanning time 10-20min is backward
Xylitol and malic acid is wherein added, continues to boil 20-30min, cool to obtain finished product.
6. a kind of application of the mulberry bavin extracting solution according to claim 3 in anti-bacteria and anti-virus, it is characterised in that：Described
Paraffin removal step can be added in step S1, to remove the wax ingredient on mulberry surface.
7. a kind of application of the mulberry bavin extracting solution according to claim 2 in anti-bacteria and anti-virus, it is characterised in that：The medicine
Its weight proportion of object each component is as follows：30 parts of mulberry bavin extracting solution, 35 parts of Flos Lonicerae extractive solution, 15 parts of radix scutellariae extracting solution, radix scrophulariae 10
Part, 8 parts of campanulaceae, 5 parts of glutinous rehmannia, 5 parts of Radix Glycyrrhizae, 10 parts of peppermint, 1 part of xylitol, 3 parts of malic acid.
8. a kind of application of the mulberry bavin extracting solution according to claim 2 in anti-bacteria and anti-virus, it is characterised in that：The medicine
Its weight proportion of object each component is as follows：40 parts of mulberry bavin extracting solution, 20 parts of Flos Lonicerae extractive solution, 25 parts of radix scutellariae extracting solution, radix scrophulariae 5
Part, 13 parts of campanulaceae, 1 part of glutinous rehmannia, 10 parts of Radix Glycyrrhizae, 5 parts of peppermint, 5 parts of xylitol, 1 part of malic acid.
9. a kind of application of the mulberry bavin extracting solution according to claim 2 in anti-bacteria and anti-virus, it is characterised in that：The medicine
Its weight proportion of object each component is as follows：35 parts of mulberry bavin extracting solution, 28 parts of Flos Lonicerae extractive solution, 20 parts of radix scutellariae extracting solution, radix scrophulariae 8
Part, 10 parts of campanulaceae, 3 parts of glutinous rehmannia, 7 parts of Radix Glycyrrhizae, 8 parts of peppermint, 3 parts of xylitol, 2 parts of malic acid.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810505647.8A CN108434244A (en) | 2018-05-24 | 2018-05-24 | A kind of application of mulberry bavin extracting solution in anti-bacteria and anti-virus |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810505647.8A CN108434244A (en) | 2018-05-24 | 2018-05-24 | A kind of application of mulberry bavin extracting solution in anti-bacteria and anti-virus |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN108434244A true CN108434244A (en) | 2018-08-24 |
Family
ID=63205421
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201810505647.8A Pending CN108434244A (en) | 2018-05-24 | 2018-05-24 | A kind of application of mulberry bavin extracting solution in anti-bacteria and anti-virus |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN108434244A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108893558A (en) * | 2018-05-24 | 2018-11-27 | 江苏海宏制药有限公司 | A kind of mulberry liquid stoste cotton fabric Antiviral breeding method and device |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1636584A (en) * | 2003-10-31 | 2005-07-13 | 成都三明药物研究所 | Medicine composition for treating upper respiratory tract infection and its prepn process |
| CN101293012A (en) * | 2008-06-20 | 2008-10-29 | 吉林省通化振国药业有限公司 | Antiviral honeysuckle flower Chinese medicine compound preparation and preparation technique |
| CN101612200A (en) * | 2009-07-31 | 2009-12-30 | 李永君 | The preparation method of plant mulberry vinegar pure solution and the application in the treatment rhinitis thereof |
| CN201986748U (en) * | 2010-12-06 | 2011-09-28 | 吴江飞翔经编纺织有限公司 | Ventilating protective fabric |
| CN106309712A (en) * | 2015-07-05 | 2017-01-11 | 刘方旭 | Traditional Chinese medicinal instant granules for treating pharyngitis and preparation method thereof |
-
2018
- 2018-05-24 CN CN201810505647.8A patent/CN108434244A/en active Pending
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1636584A (en) * | 2003-10-31 | 2005-07-13 | 成都三明药物研究所 | Medicine composition for treating upper respiratory tract infection and its prepn process |
| CN101293012A (en) * | 2008-06-20 | 2008-10-29 | 吉林省通化振国药业有限公司 | Antiviral honeysuckle flower Chinese medicine compound preparation and preparation technique |
| CN101612200A (en) * | 2009-07-31 | 2009-12-30 | 李永君 | The preparation method of plant mulberry vinegar pure solution and the application in the treatment rhinitis thereof |
| CN201986748U (en) * | 2010-12-06 | 2011-09-28 | 吴江飞翔经编纺织有限公司 | Ventilating protective fabric |
| CN106309712A (en) * | 2015-07-05 | 2017-01-11 | 刘方旭 | Traditional Chinese medicinal instant granules for treating pharyngitis and preparation method thereof |
Non-Patent Citations (1)
| Title |
|---|
| 李梅: "《中医药学基础》", 31 January 2016, 中国医药科技出版社 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108893558A (en) * | 2018-05-24 | 2018-11-27 | 江苏海宏制药有限公司 | A kind of mulberry liquid stoste cotton fabric Antiviral breeding method and device |
| CN108893558B (en) * | 2018-05-24 | 2022-04-05 | 江苏海宏制药有限公司 | Mulberry juice stock solution antiviral experimental method and device |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| KR100606452B1 (en) | A hygienic band include chinese herb medicine a composite | |
| WO2011026267A1 (en) | Antiphlogistic, antioncotic and analgesic chinese herbal composition,preparative method and usage thereof | |
| CN104940050A (en) | Use of agilawood volatile oil stoste in preparation of skin-care product | |
| CN108434244A (en) | A kind of application of mulberry bavin extracting solution in anti-bacteria and anti-virus | |
| CN101991677A (en) | Externally applied traditional Chinese medicinal liquor for treating tinea corporis | |
| CN104510641A (en) | Natural water lily eczema-removing baby oil | |
| CN106620616A (en) | Pharmaceutical composition for preventing hair loss and promoting hair growth and preparation of pharmaceutical composition | |
| CN101507743A (en) | Biennial wormwood extract and preparation method thereof | |
| CN108686058A (en) | Seven apertures rhinitis-treating spray and preparation method thereof | |
| CN113403167A (en) | Agilawood wine for tonifying yang and invigorating kidney | |
| CN105147904A (en) | Drug preventing and curing fish red skin disease | |
| CN104840505A (en) | Application of aizoon stonecrop herb to preparation of composition for inhibiting itching caused by mosquito bite | |
| CN113509537B (en) | Jiangyao bath composition capable of expelling wind, clearing away cold, inducing sweat and relieving exterior syndrome as well as preparation method and application thereof | |
| CN103610746A (en) | Wild chrysanthemum flower itch relieving dew and preparation method thereof | |
| CN102048962A (en) | Gastrodia tuber oral liquid and preparation method thereof | |
| CN107441177A (en) | A kind of tea for common cold and preparation method thereof | |
| CN108938705A (en) | Pure eucommia bark powder new preparation process | |
| CN106509279A (en) | Rosemary rose flower herb tea and preparation method thereof | |
| CN111773361A (en) | External health-care liquid and preparation method thereof | |
| JPH0692314B2 (en) | Topical skin disease treatment agent | |
| CN105168473B (en) | Liquid is embrocated in a kind of external application for treating the ringworm of scalp | |
| CN104547703A (en) | Traditional Chinese medicine composition for treating infantile eczema and preparation method of traditional Chinese medicine composition | |
| CN114129668A (en) | Production method of radix rehmanniae decoction pieces capable of calming endogenous wind and relieving itching | |
| CN117547583A (en) | Pain-relieving and cooling gel patch applicable to subacute thyroiditis | |
| CN106466343A (en) | A kind of beriberi medicament and preparation method thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20180824 |
|
| RJ01 | Rejection of invention patent application after publication |