CN106466343A - A kind of beriberi medicament and preparation method thereof - Google Patents

Abstract

The invention discloses a kind of beriberi medicament, it is that following combination of materials forms：Radix Sophorae Flavescentiss, Radix Saposhnikoviae, Realgar, Cortex Cinnamomi, violet, Radix Rosae Laevigatae, Cortex Pseudolaricis, Radix Aconiti Kusnezoffii, the present invention is good for treatment tinea pedis disease effect, and instant effect, do not feel as discomfort when with foot bath of the present invention, and material is easy to get, preparation method is simple, and price is low, can life-time service, have no toxic side effect.

Description

A kind of beriberi medicament and preparation method thereof

Technical field

The present invention relates to technical field of Chinese medicine, particularly to a kind of beriberi medicament and preparation method thereof.

Background technology

At present in China, special southern area, suffer from beriberic numerous, tinea pedis belongs to common skin diseases, at present, although the medicine species for the treatment of tinea pedis is various, during treatment, sole occurs dry and cracked, breach phenomenon, and after treating easily repeatedly.

Tinea pedis is a kind of extremely common fungal infection dermatoses.In adult, the people of 70-80% has tinea pedis, and simply weight is different.Often increase in summer, winter mitigates, and also someone is not healed all the year round.

Pathogenic bacterium polyphyly trichophyton and epidermophyton kind, main bacteria seed has trichophyton, trichophyton gypseum, acrothesium floccosum, trichophyton meginii.Trichophyton is strong because of its resistance, wayward, it has also become the Main Pathogenic Bacteria of the current tinea pedis of China.Tinea pedis is to invade the superfical mycoses of epidermis, hair and toenail, is a kind of communicable dermatosiss.Most patients are first to suffer from tinea pedis to infect hand and other positions again, tinea pedis prevalence high the reason mainly have following points ：One is that skin of sole of foot does not have sebaceous gland, lacks and can press down mycostatic fatty acid.Two is that skin of sole of foot sweat gland is abundanter, perspires more, causes to be conducive to the wet environment of fungus growth.Three is that skin of sole of foot horny layer is thicker, and the keratoprotein in horny layer is the nutrient of fungus growth.Further, since wearing footgear, local environment is sultry, sweaty foot be difficult to send out and moist, thus being more beneficial for the growth and breeding of mycete.

Content of the invention

The technical problem to be solved is to provide a kind of good for treatment tinea pedis disease effect, and instant effect, does not feel as discomfort, and material is easy to get, preparation method is simple, and price is low when with foot bath of the present invention, can life-time service, the beriberi medicament having no toxic side effect.

For achieving the above object, the present invention provides following technical scheme：A kind of beriberi medicament, it is that following combination of materials forms：Radix Sophorae Flavescentiss, Radix Saposhnikoviae, Realgar, Cortex Cinnamomi, violet, Radix Rosae Laevigatae, Cortex Pseudolaricis, Radix Aconiti Kusnezoffii.

Preferably, it is that following combination of materials forms：10-20 gram of Radix Sophorae Flavescentiss, 20-25 gram of Radix Saposhnikoviae, 30-50 gram of Realgar, 5-10 gram of Cortex Cinnamomi, 10-20 gram of violet, 15-25 gram of Radix Rosae Laevigatae, 3-9 gram of Cortex Pseudolaricis, 10-20 gram of Radix Aconiti Kusnezoffii.

More preferred, it is that following combination of materials forms：15 grams of Radix Sophorae Flavescentiss, 22 grams of Radix Saposhnikoviae, 40 grams of Realgar, 8 grams of Cortex Cinnamomi, 15 grams of violet, 20 grams of Radix Rosae Laevigatae, 5 grams of Cortex Pseudolaricis, 15 grams of Radix Aconiti Kusnezoffii.

Another aspect of the present invention additionally provides a kind of preparation method of beriberi medicament, and it comprises the steps：

The first step, described component is mixed in described ratio, plus the deionized water with respect to 3～6 times of described mixture quality, carry out decocting 2～4 hours, filter, the filtering residue obtaining adds deionized water with respect to 0.5～1 times of described mixture quality further, decocts 1 again ～2 hours, filter, the filtrate obtaining twice is mixed, carries out concentrating under reduced pressure, being concentrated into temperature is that when 70 DEG C, relative density is 1.29～1.32 Mastic；

Second step, the ethanol being 85%～95% with respect to the determining alcohol of 3～5 times of mastic quality is added in the mastic that the first step obtains, stirring and dissolving obtains ethanol solution, and ethanol solution is stood 24～36 hours under conditions of 5 DEG C～10 DEG C, adopt percolation with per minute 1～ The speed of 2ml slowly percolation, collects percolate, is concentrated and dried, is ground into powder；

3rd step, the powder obtaining in second step carries out pack packaging, forms one bag of bagged steeping drug.

Beneficial effect using above technical scheme is：The present invention is good for treatment tinea pedis disease effect, and instant effect does not feel as discomfort when with foot bath of the present invention, and material is easy to get, and preparation method is simple, and price is low, can life-time service, have no toxic side effect.

It is below the material source of the present invention：

Its hardship of Radix Sophorae Flavescentiss, trembles with fear.There are heat clearing and damp drying, parasite killing, the work(of diuresis.For hematodiarrhoea, have blood in stool, jaundice urine retention, leucorrhea with red and white discharge, swelling of the vulva pudendal pruritus, eczema, eczema, skin pruritus, scabies leprosy, external treatment trichomonal vaginitis.

Radix Saposhnikoviae acrid in the mouth, sweet, slightly warm in nature.There are expelling pathogenic wind from the body surface, removing dampness to relieve pain, effect of relieving convulsion.

The pungent taste of Realgar Realgar, warm in nature, Return liver, large intestine channel, there is removing toxic substances parasite killing, removing dampness and eliminating phlegm, effect of preventing the attack (or recurrence) of malaria, for carbuncle swells furunculosis, snake bite and insect sting, abdominal pain due to worm stagnation, infantile convulsion, malaria.

Cortex Cinnamomi acrid in the mouth, sweet, extremely hot in nature, return kidney, spleen, the heart, Liver Channel, have mends fire supporing yang, guiding fire to origin, dispersing cold for relieving pain, effect of promoting the flow of QI-blood by warming the meridian, for sexual impotence cold womb, chills and pain of the waist and kness, kidney deficiency is breathed heavily, upward floating of YANG in deficiency condition, dizziness conjunctival congestion, trusted subordinate's crymodynia, cold of insufficiency type vomiting and diarrhea, cold hernia stomachache, dysmenorrhea amenorrhea.

Violet has skin care, the moistening face of smoothing wrinkle speckle removing, is not only suitable for people seeking beauty and drinks, and meanwhile, to sore throat, bronchitis, constipation, removes halitosiss（As pick up with lavandula angustifolia join better）Effective in cure.

Radix Rosae Laevigatae nature and flavor are sour and astringent, put down, have functions that reinforcing the kidney and controlling nocturnal emission, control spermatorrhea, the enuresis, dysentery is had loose bowels, bleeding not during menses, uterine prolapse, and haemorrhoids is scalded.

Cortex Pseudolaricis have functions that Anti-Puritic and insecticidal, for trick tinea, neurodermatitiss, eczema, leprosy dysentery head.External root bark or near root bark steeping in wine（Cortex Pseudolaricis tincture）Put on the skin outward；Or finely ground powder dresses affected part with vinegar.

Radix Aconiti Kusnezoffii acrid in the mouth, hardship, property heat, GUIXIN, liver,kidney,spleen warp, there is expelling wind and removing dampness, effect of antalgic, for anemofrigid-damp arthralgia, arthralgia, trusted subordinate's crymodynia, colic of cold type is had a pain and narcotic analgesic.

Specific embodiment

Technical scheme in the embodiment of the present invention will be clearly and completely described below it is clear that described embodiment is only a part of embodiment of the present invention, rather than whole embodiments.

A kind of beriberi medicament, it is that following combination of materials forms：Radix Sophorae Flavescentiss, Radix Saposhnikoviae, Realgar, Cortex Cinnamomi, violet, Radix Rosae Laevigatae, Cortex Pseudolaricis, Radix Aconiti Kusnezoffii.

Take 15 grams of Radix Sophorae Flavescentiss, 22 grams of Radix Saposhnikoviae, 40 grams of Realgar, 8 grams of Cortex Cinnamomi, 15 grams of violet, 20 grams of Radix Rosae Laevigatae, 5 grams of Cortex Pseudolaricis, 15 grams of Radix Aconiti Kusnezoffii, plus the deionized water with respect to 3～6 times of described mixture quality, carry out decocting 2～4 hours, filter, the deionized water with respect to 0.5～1 times of described mixture quality is added further in the filtering residue obtaining, decoct 1～2 hour again, filter, the filtrate obtaining twice is mixed, carry out concentrating under reduced pressure, being concentrated into temperature is that when 70 DEG C, relative density is 1.29～1.32 Mastic；The ethanol being 85%～95% with respect to the determining alcohol of 3～5 times of mastic quality will be added in the mastic of acquisition, stirring and dissolving obtains ethanol solution, ethanol solution is stood 24～36 hours under conditions of 5 DEG C～10 DEG C, adopt percolation with per minute 1～ The speed of 2ml slowly percolation, collects percolate, is concentrated and dried, is ground into powder；The powder of acquisition is carried out pack packaging, forms one bag of bagged steeping drug.

For the ease of facts have proved, applicant have chosen 100 tinea pedis patient's experiment Analysis and contrast, wherein male patient 60, female patient 40, after the treatment of half a year, successfully cures 90, success rate is 90%, therefore the present invention has good curative effect, effectively can effect a radical cure tinea pedis, and does not all find in above-mentioned clinical practice that patient produces drug resistance or side effect.

Above-described be only the preferred embodiment of the present invention it is noted that for the person of ordinary skill of the art, without departing from the concept of the premise of the invention, can also make some deformation and improve, these broadly fall into protection scope of the present invention.

Claims (4)

1. a kind of beriberi medicament is it is characterised in that it is following combination of materials forms：Radix Sophorae Flavescentiss, Radix Saposhnikoviae, Realgar, Cortex Cinnamomi, violet, Radix Rosae Laevigatae, Cortex Pseudolaricis, Radix Aconiti Kusnezoffii.

2. a kind of beriberi medicament according to claim 1 is it is characterised in that it is following combination of materials forms：10-20 gram of Radix Sophorae Flavescentiss, 20-25 gram of Radix Saposhnikoviae, 30-50 gram of Realgar, 5-10 gram of Cortex Cinnamomi, 10-20 gram of violet, 15-25 gram of Radix Rosae Laevigatae, 3-9 gram of Cortex Pseudolaricis, 10-20 gram of Radix Aconiti Kusnezoffii.

3. a kind of beriberi medicament according to claim 1 and 2 is it is characterised in that it is following combination of materials forms：15 grams of Radix Sophorae Flavescentiss, 22 grams of Radix Saposhnikoviae, 40 grams of Realgar, 8 grams of Cortex Cinnamomi, 15 grams of violet, 20 grams of Radix Rosae Laevigatae, 5 grams of Cortex Pseudolaricis, 15 grams of Radix Aconiti Kusnezoffii.

4. a kind of preparation method of the beriberi medicament according to claims 1 to 3 is it is characterised in that it comprises the steps：

The first step, described component is mixed in described ratio, plus the deionized water with respect to 3～6 times of described mixture quality, carry out decocting 2～4 hours, filter, the filtering residue obtaining adds deionized water with respect to 0.5～1 times of described mixture quality further, decocts 1 again ～2 hours, filter, the filtrate obtaining twice is mixed, carries out concentrating under reduced pressure, being concentrated into temperature is that when 70 DEG C, relative density is 1.29～1.32 Mastic；

Second step, add in the mastic that the first step obtains with respect to mastic quality 3～ 5 times of determining alcohol is 85%～95% ethanol, and stirring and dissolving obtains ethanol solution, and ethanol solution is stood 24～36 hours under conditions of 5 DEG C～10 DEG C, adopt percolation with per minute 1～ The speed of 2ml slowly percolation, collects percolate, is concentrated and dried, is ground into powder；

3rd step, the powder obtaining in second step carries out pack packaging, forms one bag of bagged steeping drug.