CN108434129A - 用于联合治疗的药物组合物 - Google Patents

用于联合治疗的药物组合物 Download PDF

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Publication number
CN108434129A
CN108434129A CN201810575583.9A CN201810575583A CN108434129A CN 108434129 A CN108434129 A CN 108434129A CN 201810575583 A CN201810575583 A CN 201810575583A CN 108434129 A CN108434129 A CN 108434129A
Authority
CN
China
Prior art keywords
tesofensine
metoprolol
pharmaceutically acceptable
obesity
treatment
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201810575583.9A
Other languages
English (en)
Chinese (zh)
Inventor
亨里克·比约克·汉森
莫滕·格伦内特
博·约尔特·本特森
拉尔斯·伊韦莱德-尼尔森
约尔延·布斯·拉森
克劳斯·松德格伦
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aniona APS
Original Assignee
Aniona APS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aniona APS filed Critical Aniona APS
Publication of CN108434129A publication Critical patent/CN108434129A/zh
Pending legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/46—8-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Organic Chemistry (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Emergency Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Endocrinology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CN201810575583.9A 2012-02-16 2013-02-14 用于联合治疗的药物组合物 Pending CN108434129A (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201261599623P 2012-02-16 2012-02-16
US61/599,623 2012-02-16
DKPA201270076 2012-02-16
DKPA201270076 2012-02-16
CN201380020405.5A CN104244935A (zh) 2012-02-16 2013-02-14 用于联合治疗的药物组合物

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CN201380020405.5A Division CN104244935A (zh) 2012-02-16 2013-02-14 用于联合治疗的药物组合物

Publications (1)

Publication Number Publication Date
CN108434129A true CN108434129A (zh) 2018-08-24

Family

ID=48983571

Family Applications (3)

Application Number Title Priority Date Filing Date
CN201810575583.9A Pending CN108434129A (zh) 2012-02-16 2013-02-14 用于联合治疗的药物组合物
CN201380020405.5A Pending CN104244935A (zh) 2012-02-16 2013-02-14 用于联合治疗的药物组合物
CN201810580312.2A Pending CN108853071A (zh) 2012-02-16 2013-02-14 用于联合治疗的药物组合物

Family Applications After (2)

Application Number Title Priority Date Filing Date
CN201380020405.5A Pending CN104244935A (zh) 2012-02-16 2013-02-14 用于联合治疗的药物组合物
CN201810580312.2A Pending CN108853071A (zh) 2012-02-16 2013-02-14 用于联合治疗的药物组合物

Country Status (14)

Country Link
US (5) US9211271B2 (cg-RX-API-DMAC7.html)
EP (1) EP2814473B1 (cg-RX-API-DMAC7.html)
JP (1) JP6203760B2 (cg-RX-API-DMAC7.html)
CN (3) CN108434129A (cg-RX-API-DMAC7.html)
AU (1) AU2013220424B2 (cg-RX-API-DMAC7.html)
CA (1) CA2864264C (cg-RX-API-DMAC7.html)
DK (1) DK2814473T3 (cg-RX-API-DMAC7.html)
EA (1) EA029543B1 (cg-RX-API-DMAC7.html)
ES (1) ES2704987T3 (cg-RX-API-DMAC7.html)
HR (1) HRP20190050T1 (cg-RX-API-DMAC7.html)
LT (1) LT2814473T (cg-RX-API-DMAC7.html)
PL (1) PL2814473T3 (cg-RX-API-DMAC7.html)
SI (1) SI2814473T1 (cg-RX-API-DMAC7.html)
WO (1) WO2013120935A1 (cg-RX-API-DMAC7.html)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EA029543B1 (ru) * 2012-02-16 2018-04-30 Саниона А/С Способ лечения, профилактики или уменьшения сердечно-сосудистых побочных эффектов тезофенсина
EP3087798A4 (en) * 2013-12-28 2017-08-30 Intel Corporation System and method for device action and configuration based on user context detection from sensors in peripheral devices
HUE055974T2 (hu) 2015-03-03 2022-01-28 Saniona As Tesofensine és metoprolol kombinációs készítmény
US20190060301A1 (en) 2016-01-15 2019-02-28 Saniona A/S Tesofensine and metoprolol for treatment of hypertension
KR20190050784A (ko) 2016-09-07 2019-05-13 사니오나 에이/에스 테소펜신 조성물
WO2020144146A1 (en) 2019-01-07 2020-07-16 Saniona A/S Tesofensine for reduction of body weight in prader-willi patients
CN110297826B (zh) * 2019-05-31 2020-12-11 南京理工大学 基于json动态解析卫星遥测数据的方法
MX2022013236A (es) 2020-04-22 2023-01-24 Saniona As Tratamiento de la obesidad hipotalamica.

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992016197A1 (en) * 1991-03-18 1992-10-01 Sepracor Inc. Composition and method containing optically pure (s) metoprolol
WO2009080693A2 (en) * 2007-12-20 2009-07-02 Neurosearch A/S Pharmaceutical composition comprising tesofensine or its analogue and a beta blocker

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA971525B (en) 1996-02-22 1997-10-21 Neurosearch As Tropane derivatives, their preparation and use.
CA2553649A1 (en) 2004-01-22 2005-08-04 Neurosearch A/S Compounds for the sustained reduction of body weight
WO2009065845A1 (en) 2007-11-20 2009-05-28 Neurosearch A/S A method for treating over-eating disorders
US20100317572A1 (en) 2007-12-20 2010-12-16 Neurosearch A/S Pharmaceutical composition comprising tesofensine or its analogue and an anti-obesity compound
US9408837B2 (en) 2008-05-28 2016-08-09 Kitov Pharmaceutical Ltd. Ameliorating drug-induced elevations in blood pressure by adjunctive use of antihypertensive drugs
EA029543B1 (ru) * 2012-02-16 2018-04-30 Саниона А/С Способ лечения, профилактики или уменьшения сердечно-сосудистых побочных эффектов тезофенсина
HUE055974T2 (hu) * 2015-03-03 2022-01-28 Saniona As Tesofensine és metoprolol kombinációs készítmény

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992016197A1 (en) * 1991-03-18 1992-10-01 Sepracor Inc. Composition and method containing optically pure (s) metoprolol
WO2009080693A2 (en) * 2007-12-20 2009-07-02 Neurosearch A/S Pharmaceutical composition comprising tesofensine or its analogue and a beta blocker

Also Published As

Publication number Publication date
JP6203760B2 (ja) 2017-09-27
US20160074344A1 (en) 2016-03-17
US9387184B2 (en) 2016-07-12
JP2015508765A (ja) 2015-03-23
EP2814473A1 (en) 2014-12-24
WO2013120935A1 (en) 2013-08-22
PL2814473T3 (pl) 2019-06-28
US20220016055A1 (en) 2022-01-20
EA201491532A1 (ru) 2015-01-30
LT2814473T (lt) 2019-01-25
US20170007557A1 (en) 2017-01-12
US20180185304A1 (en) 2018-07-05
US9211271B2 (en) 2015-12-15
CN108853071A (zh) 2018-11-23
ES2704987T3 (es) 2019-03-21
SI2814473T1 (sl) 2019-03-29
EA029543B1 (ru) 2018-04-30
EP2814473B1 (en) 2018-10-10
CN104244935A (zh) 2014-12-24
CA2864264C (en) 2020-05-05
US20150025107A1 (en) 2015-01-22
DK2814473T3 (en) 2019-01-28
AU2013220424B2 (en) 2017-03-23
CA2864264A1 (en) 2013-08-22
HK1204946A1 (en) 2015-12-11
AU2013220424A1 (en) 2014-09-25
HRP20190050T1 (hr) 2019-03-08

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Application publication date: 20180824