CN108432751A - A kind of pesticide microcapsule suspending agent and its preparation method and application - Google Patents
A kind of pesticide microcapsule suspending agent and its preparation method and application Download PDFInfo
- Publication number
- CN108432751A CN108432751A CN201810259345.7A CN201810259345A CN108432751A CN 108432751 A CN108432751 A CN 108432751A CN 201810259345 A CN201810259345 A CN 201810259345A CN 108432751 A CN108432751 A CN 108432751A
- Authority
- CN
- China
- Prior art keywords
- suspending agent
- microcapsule suspending
- agent
- rynaxypyr
- benzoate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
- A01N25/26—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests in coated particulate form
- A01N25/28—Microcapsules or nanocapsules
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
- A01N25/02—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests containing liquids as carriers, diluents or solvents
- A01N25/04—Dispersions, emulsions, suspoemulsions, suspension concentrates or gels
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
- A01N43/56—1,2-Diazoles; Hydrogenated 1,2-diazoles
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/90—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Dentistry (AREA)
- Plant Pathology (AREA)
- Engineering & Computer Science (AREA)
- Pest Control & Pesticides (AREA)
- Agronomy & Crop Science (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Environmental Sciences (AREA)
- Toxicology (AREA)
- Chemical & Material Sciences (AREA)
- Dispersion Chemistry (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
The invention discloses a kind of pesticide microcapsule suspending agents and its preparation method and application.The microcapsule suspending agent is grouped as by the group of following weight ratio：Pesticide active ingredient 0.5 30%, cyst material 1% 20%, emulsifier 1 5%, dispersant 1 5%, wetting agent 1 3%, pH adjusting agent 0.1 5%, thickener 0.05 0.3%, antifoaming agent 0.1 0.2%, water complements to 100%.Microcapsule suspending agent of the present invention is prepared using micro-suspension polymerization, agriculture the effective elements of the medicine is ground to grain size (D90) ＜ 2um in water phase or oil-based system, it is prepared into microcapsule suspending agent by macromolecular polymerization reaction, this method dissolving pesticide activity component does not use or seldom uses organic solvent, has the advantages that environmental protection.Microcapsule suspending agent pesticidal preparations of the present invention can be effectively reduced the degradation rate of pesticide activity component in the environment in use, improve drug effect and extend the prevention time.
Description
Technical field
The present invention relates to a kind of pesticide microcapsule suspending agents and its preparation method and application, belong to field of pesticide preparation.
Background technology
Microcapsule suspending agent be using high molecular material as cyst wall or cyst membrane, by chemistry, physics or physicochemical method,
It wraps up, is formed after being dissolved with organic solvent as the liquid pesticide active constituent of the capsule heart or solid active compound active constituent
A kind of microencapsulation with semipermeability cyst membrane, and they are steadily disperseed using certain concentration, is suspended in as continuous
In the water of phase.Microcapsule suspending agent has the advantage that as a kind of novel agrochemical dosage form：
1. oil phase and water phase are separated, the pesticide activity component of hydrolabil, it is difficult to aqueous emulsion and microemulsion be made, but
It can be made into microcapsule formulations.
2. inhibiting caused by environmental factor (such as light, heat, air, rainwater, soil, microorganism) and other chemical substances
The decomposition of active constituent improves the stability of medicament itself.
3. cyst membrane can inhibit the volatility of pesticide, shelter its original peculiar smell.And the steaming of volatility pesticide can be reduced
Speed is sent out, extraneoas loss caused by the volatilization by pesticide is reduced, improves the bioavailability of active ingredient.
4. introducing the function of control release, extend its lasting period, reduce the quantity and frequency of dispenser, improves pesticide to environment
Pressure.
5. reducing the harmfulness of organic solvent.Physicochemical properties of many pesticide activity components due to itself, it is difficult to
It is processed into environmentally friendly water-based aerosol, is typically only capable to be processed into missible oil sale, a large amount of uses of organic solvent are to the mankind
Living environment brings great burden.The characteristics such as organic solvent flash-point, burning point be low simultaneously to storage, conveyer belt come it is prodigious not
Just.
6. effective compounding for a variety of pesticidal active substances of different nature provides great convenience
7. reducing poisoning.Due to the presence of cyst wall, pesticide activity component needs the breakage by microcapsules or diffusion ability
Show its toxicity, thus toxicity of certain pesticide activity components to crop can be reduced.
8. reducing acute toxicity.Microcapsule formulations can significantly reduce toxicity of the pesticidal preparations product to mammal.Find out, it is micro-
The above-mentioned function of capsule, no matter for existing pesticide species improve and perfect, or facilitate the successful exploitation of new varieties of pesticides
And popularization and application, all will be extremely important.
There are two types of existing common pesticide micro capsule preparation methods, a kind of situ aggregation method, a kind of interfacial polymerization hair, and two
Kind of method has ripe product to put into production sale in the domestic market.But there are some technologies in both technical solutions
Defect.
1. using not environmentally problem caused by organic solvent or high toxicity polymer material, with the environmental protection of pesticidal preparations
Trend is not obviously inconsistent.
2. two methods are only applicable to the preferable pesticide activity component of dissolubility in organic solvent, for oil-soluble compared with
The pesticide activity component of difference, it is difficult to prepare micro-capsule suspension.Emamectin-benzoate dissolves in polar solvent
Property is preferable, and solubility is poor in nonpolar solvent, and polar solvent is not suitable for preparing microcapsules.Rynaxypyr has largely
Solubility is poor in solvent.
To solve the above-mentioned problems, the present invention provides a kind of more environmentally-friendly, while to the wider array of micro- glue of active compound adaptability
The preparation method of capsule suspension pesticide preparation.
Invention content
The object of the present invention is to provide a kind of microcapsule suspending agents.
It is a further object of the present invention to provide the preparation methods of the microcapsule suspending agent.
It is yet another object of the invention to provide the applications of the microcapsule suspending agent.
A kind of microcapsule suspending agent is grouped as by the group of following weight ratio：Pesticide active ingredient 0.5%-30%, cyst material
1%-20%, emulsifier 1%-5%, dispersant 1%-5%, wetting agent 0.1%-3%, pH adjusting agent 0.1%-5%, thickener
0.05%-0.3%, antifoaming agent 0.1%-0.2%, water complement to 100%；
The pesticide active ingredient is selected from Rynaxypyr and/or emamectin-benzoate or Avermectin
One kind in element；
The cyst material is selected from：Lauxite, polyureas, polyisocyanates, gelatin, Arabic gum, melamine first
One or more combination in urea formaldehyde or cyanurotriamide modified urea resin；
The emulsifier is selected from：Fatty alcohol polyoxyethylene ether, alkyl phenol polyoxyethylene ether, cardanol polyoxyethylene ether,
Castor oil polyoxyethylene ether, tween, this disk, calcium dodecyl benzene sulfonate, agriculture breast 600#, agriculture breast 1601#, agriculture breast 1602#, agriculture breast
It is one or more in 700#；
The dispersant is selected from：Aliphatic alcohol polyoxyvinethene phosphate, polycarboxylate salt dispersant, EO-PO block polyethers,
Or alkylnaphthalene sulfonate；
The wetting agent is selected from：Lauryl sodium sulfate, fatty alcohol polyoxyethylene ether sulfate, alkylnaphthalene sulfonate,
Fatty alcohol polyoxyethylene ether, SOPA-270, disecoctylmaleate sodium sulfonate；
The pH adjusting agent is selected from：One in hydrochloric acid, glacial acetic acid, ammonium chloride, ethylenediamine, triethylamine or triethanolamine
Kind or arbitrary several combinations；
The thickener is selected from：Xanthans, polyvinyl alcohol 1788, Macrogol 4000, Macrogol 6000, magnesium silicate
Aluminium or lithium magnesium silicate；
The antifoaming agent is selected from：The antifoaming agent of one or both of organic silicon defoamer, polyether antifoam agent type
Mixture.
Microcapsule suspending agent of the present invention is preferably mainly grouped as by the group of following weight ratio：Pesticide active ingredient 5-15%, capsule
Wall material 9%-15%, emulsifier 1%-3%, dispersant 1%-3%, wetting agent 0.1%-1%, pH adjusting agent 0.1%-5%,
Thickener 0.05%-0.3%, antifoaming agent 0.1%-0.2%, water complement to 100%.
Wherein, the preferred emamectin-benzoate of the pesticide active ingredient and Rynaxypyr or Ah
Rhzomorph and Rynaxypyr, particularly preferred emamectin-benzoate and Rynaxypyr are tieed up described micro-
Weight percentage in capsule suspending agent is 1%-10% and 1%-20%.
The preferred Lauxite of the cyst material, melamine resin or cyanurotriamide modified urea resin.
The pesticide active ingredient of the microcapsule suspending agent be single active ingredient emamectin-benzoate, Ah
When tieing up rhzomorph or Rynaxypyr, prepared by micro capsule technology；The pesticide active ingredient be two kinds of activity at
When point emamectin-benzoate and Rynaxypyr or avermectin and Rynaxypyr, can by with
Lower three kinds of different methods obtain the microcapsule suspending agent, 1. prepare micro-capsule using a kind of technique after two kinds of active components mixing
Suspending agent, 2. two kinds of active components prepared respectively using different technique remix after microcapsule suspending agent uniformly compounded it is micro-
Capsule preparation, 3. one kind preparing microcapsule suspending agent by micro capsule technology in two kinds of active components, and another ingredient uses grinding work
Skill is prepared into suspending agent, and the two, which remixes, uniformly obtains the microcapsule suspending agent.
The preferred micro suspension situ aggregation method of preparation process of microcapsule suspending agent.
The preparation process of the micro suspension situ aggregation method is more preferably：
(1) preparation of fine suspension：By pesticide active principle, wetting agent, dispersant, emulsifier, antifoaming agent and a certain amount of
Water mixing after using sand mill be ground to grain size D90 ＜ 2um, obtain the fine suspension A of active component；
(2) preparation of cyst material performed polymer：By formaldehyde and urea or melamine and formaldehyde or melamine,
Formaldehyde and urea stir evenly, 200-300 revs/min of rotating speed, and aqueous slkali is added and adjusts pH=8-9, are warming up to 70 DEG C, heat preservation
1h obtains cyst material prepolymer solution B；
(3) preparation of microcapsules：Obtained cyst material prepolymer solution B is added in suspending liquid A, 1000-1500 turns/
Minute high-speed stirred is uniform；Mixing speed is reduced to 500-600 revs/min, pH adjusting agent regulation system pH to 2.5-4.5 is added
Encystation polymerisation is catalyzed to occur；It is 200-300 revs/min to gradually reduce rotating speed, and is gradually warming up to 40-60 DEG C of solidification capsule
Wall is added thickener and remaining water, stirs evenly until pH adjusting agent is added after reaction end is adjusted to neutrality by system pH to obtain the final product
The microcapsule suspending agent.
When two kinds of ingredients compoundings of the microcapsule suspending agent and the non-micro-capsule of one of which ingredient, preparation method is preferred,
The suspending agent liquid of another active constituent is added in microcapsule suspending agent prepared by the above method, by stirring evenly
The microcapsule suspending agent of different conditions is in two kinds of active components.
The preparation method of microcapsule suspending agent of the present invention, comprises the steps of：
The pesticide active ingredient of the microcapsule suspending agent be single active ingredient emamectin-benzoate, Ah
When tieing up rhzomorph or Rynaxypyr, prepared by micro capsule technology；The pesticide active ingredient be two kinds of activity at
When point emamectin-benzoate and Rynaxypyr or avermectin and Rynaxypyr, can by with
Lower three kinds of different methods obtain the microcapsule suspending agent, 1. former using a kind of micro suspension simultaneously after two kinds of active components mixing
Position polymerization prepares microcapsule suspending agent, and 2. two kinds of active components remix after preparing microcapsule suspending agent respectively using different technique
The microcapsule formulation uniformly compounded, 3. one kind preparing microcapsule suspension by micro suspension situ aggregation method in two kinds of active components
Agent, another ingredient are prepared into suspending agent using grinding technics, and the two, which remixes, uniformly obtains the microcapsule suspending agent.
The preparation method preferably includes：
(1) preparation of fine suspension：By pesticide active principle, wetting agent, dispersant, emulsifier, antifoaming agent and a certain amount of
Water mixing after using sand mill be ground to grain size D90 ＜ 2um, obtain the fine suspension A of active component；
(2) preparation of cyst material performed polymer：By formaldehyde and urea or melamine and formaldehyde or melamine,
Formaldehyde and urea stir evenly, 200-300 revs/min of rotating speed, and aqueous slkali is added and adjusts pH=8-9, are warming up to 70 DEG C, heat preservation
1h obtains cyst material prepolymer solution B；
(3) preparation of microcapsules：Obtained cyst material prepolymer solution B is added in suspending liquid A, 1000-1500 turns/
Minute high-speed stirred is uniform；Mixing speed is reduced to 500-600 revs/min, pH adjusting agent regulation system pH to 2.5-4.5 is added
Encystation polymerisation is catalyzed to occur；It is 200-300 revs/min to gradually reduce rotating speed, and is gradually warming up to 40-60 DEG C of solidification capsule
Wall is added thickener and remaining water, stirs evenly until pH adjusting agent is added after reaction end is adjusted to neutrality by system pH to obtain the final product
The microcapsule suspending agent.
Application of the microcapsule suspending agent in the insect pest for preventing veterinary antibiotics, field crop.
Compared with prior art, the beneficial effects of the invention are as follows：
(1) high efficiency：The function of introducing sustained release, extends the lasting period of pesticide activity component, reduces the quantity of dispenser
And frequency, work efficiency several times can be greatly improved, cost of labor is reduced.
(2) anti-light solution：Photodissociation is rapid in its natural state for emamectin-benzoate, when being in microcapsules state
It can not be illuminated by the light decomposition with effective protection emamectin-benzoate, extend emamectin-benzoate
Lasting period.
(3) Environmental Safety：The characteristics such as organic solvent flash-point, burning point be low carry out big inconvenience to storage, conveyer belt.The present invention
The microcapsule suspending agent is prepared using micro-suspension polymerization, and agriculture the effective elements of the medicine is ground in water phase or oil-based system
To grain size (D90) ＜ 2um, microcapsule suspending agent is prepared by macromolecular polymerization reaction, this method dissolves pesticide activity component not
Using or seldom use organic solvent, greatly reduce harmfulness of the organic solvent to environment, have the advantages that environmental protection.
(4) safely and effectively：Due to the presence of cyst wall, pesticide activity component needs the breakage by microcapsules or diffusion ability
Show its toxicity, toxicity of the pesticidal preparations product to mammal can be significantly reduced, while pesticide activity component can also be reduced
To the toxicity of crop, microcapsule suspending agent pesticidal preparations of the present invention can be effectively reduced in use pesticide activity at
Divide degradation rate in the environment, improve drug effect and extends the prevention time.
Specific implementation mode
The embodiment of the invention discloses a kind of microcapsule suspending agent pesticidal preparations.Those skilled in the art can use for reference in this paper
Hold, is suitably modified technological parameter realization.In particular, it should be pointed out that all similar substitutions and modifications are to those skilled in the art
For be it will be apparent that they are considered as being included in scope of the invention.The product of the present invention is by preferably implementing
Example is described, related personnel obviously can not depart from the content of present invention, in spirit and scope to product as described herein into
Row change is suitably changed and is combined, to realize and apply the technology of the present invention.
Embodiment 1:8% emamectin-benzoate micro-capsule suspension
Formula：(polycarboxylate salt dispersant, Sol tie up (Zhenjiang) by emamectin-benzoate 8kg, dispersant T36
Chemical Company, similarly hereinafter) 2kg, emulsifier：Tween-80 2kg, fatty alcohol polyethenoxy ether class wetting agent：IGEBAL
BC/10 (Rhodia) 0.5kg, cyanurotriamide modified urea resin 15kg (urea 5.1kg, melamine 4.5kg, 37% formaldehyde
5.4kg), xanthans 0.1kg, organic silicon defoamer 0.2kg, pH adjusting agent：In right amount, water complements to 100kg.
Preparation process：
1. the preparation of fine suspension：By emamectin-benzoate 8kg, T36 2kg, Tween-80 2kg,
IGEBAL BC/10 0.5kg, triethanolamine 0.2kg, organic silicon defoamer 0.2kg, water 70kg, are ground after mixing using sand mill
Grain size D90 ＜ 2um are milled to, the fine suspension A of active component is obtained；Wherein triethylamine alcohol has as pH adjusting agent in grinding
Help reduce the viscosity of emamectin benzoate suspension；
2. the preparation of cyst material performed polymer：In the container equipped with thermometer, agitating device, by urea 5.1kg, trimerization
Cyanamide 4.5kg is added in 37% formaldehyde 5.4kg and stirs, 200 revs/min of rotating speed, and sodium hydroxide solution is added and adjusts pH=
8.5,70 DEG C are warming up to, 1h is kept the temperature, obtains cyst material prepolymer solution B.
3. the preparation of microcapsules：Obtained cyst material prepolymer solution B is added in suspending liquid A, high-speed stirred is added (to turn
1500 revs/min of speed) uniformly；Mixing speed is reduced to 600 revs/min, it is 3.5 catalysis that hydrochloric acid or acetic acid regulation system pH, which is added,
Encystation polymerisation occurs, and it is 300 revs/min to gradually reduce rotating speed, and is gradually warming up to 45 DEG C of solidification cyst walls, until reaction end
Sodium hydroxide solution cooperation regulation system pH is added afterwards and is adjusted to neutrality, 0.1kg xanthans is added and adjusts viscosity, supplies water extremely
100kg is to get the microcapsule suspending agent pesticidal preparations.
Embodiment 2:10% Rynaxypyr microcapsule suspending agent
Formula：(phosphoric acid ester dispersant, it is limited that Sol ties up (Zhenjiang) chemicals by Rynaxypyr 10kg, dispersant FD
Company) 2kg, emulsifier tween 80 3kg, wetting agent IGEBAL BC/10 (Rhodia) 0.5kg, melamine modified urea-formaldehyde tree
Fat 15kg (urea 5.1kg, melamine 4.5kg, 37% formaldehyde 5.4kg), xanthans：0.1kg, organic silicon defoamer 0.2kg
PH adjusting agent：In right amount, water complements to 100kg.
Preparation process：
1. the preparation of fine suspension：Rynaxypyr 10kg, it IGEBAL BC/10 (Rhodia) 0.5kg, FD 2kg, spits
80 3kg of temperature, antifoaming agent 0.2kg, water 70kg, are ground to grain size D90 ＜ 2um using sand mill after mixing, obtain active component
Fine suspension A.
2. the preparation of cyst material performed polymer：In the container equipped with thermometer, agitating device, by urea 5.1kg, trimerization
Cyanamide 4.5kg is added in 37% formaldehyde 5.4kg and stirs, 300 revs/min of rotating speed, and sodium hydroxide solution is added and adjusts pH=
8.5,70 DEG C are warming up to, 1h is kept the temperature, obtains cyst material prepolymer solution B.
3. the preparation of microcapsules：Obtained cyst material prepolymer solution B is added in suspending liquid A, high-speed stirred is added (to turn
1000 revs/min of speed) uniformly；Mixing speed is reduced to 500 revs/min, it is poly- that the catalysis encystation of hydrochloric acid regulation system pH to 3.5 is added
Close reaction；It is 200 revs/min to gradually reduce rotating speed, and is gradually warming up to 45 DEG C of solidification cyst walls, until being added after reaction end
System pH is adjusted to neutrality by sodium hydroxide solution, and 0.1kg xanthans is added and adjusts viscosity, supplies water to 100kg to get described
Microcapsule suspending agent pesticidal preparations.
Embodiment 3:5% emamectin benzoate Rynaxypyr microcapsule suspending agent
Formula：(the Jinan Australia Xinghua emamectin-benzoate 2kg, Rynaxypyr 3kg, emulsifier By125
Work Co., Ltd) 2kg, dispersant SC (Dongguan City Ke Ruida Chemical Industry Science Co., Ltd) 2kg, wetting agent IGEBAL BC/10
(Rhodia) 0.3kg, cyanurotriamide modified urea resin 10kg (urea 3.4kg, melamine 3kg, 37% formaldehyde 3.6kg),
Xanthans：0.2Kg, antifoaming agent 0.2kg, appropriate pH adjusting agent, water complement to 100kg.
Preparation process：
1. the preparation of fine suspension：By emamectin-benzoate 2kg, Rynaxypyr 3kg, By125
2kg, SC 2kg, IGEBAL BC/10 (Rhodia) 0.3kg, triethanolamine 0.2kg, antifoaming agent 0.2kg, water 40kg, after mixing
Grain size D90 ＜ 2um are ground to using sand mill, obtain the fine suspension A of active component.
2. the preparation of cyst material performed polymer：In the container equipped with thermometer, agitating device, by urea 3.4kg, trimerization
Cyanamide 3kg is added in 37% formaldehyde 3.6kg and stirs, 250 revs/min of rotating speed, and sodium hydroxide solution is added and adjusts pH=8.5,
70 DEG C are warming up to, 1h is kept the temperature, obtains cyst material prepolymer solution B.
3. the preparation of microcapsules：Obtained cyst material prepolymer solution B is added in suspending liquid A, high-speed stirred is added (to turn
1500 revs/min of speed) uniformly；Mixing speed is reduced to 500 revs/min, it is that 3.5 catalysis encystation are poly- that hydrochloric acid regulation system pH, which is added,
Close reaction；It is 300 turns to gradually reduce rotating speed, and is gradually warming up to 45 DEG C of solidification cyst walls, until hydrogen-oxygen is added after reaction end
Change sodium solution cooperation conditioning agent and system pH be adjusted to neutrality, 0.1kg xanthans is added and adjusts viscosity, supply water to 100kg to get
The micro-capsule suspension pesticidal preparations.
4 9% emamectin benzoate Rynaxypyr microcapsule suspending agent of embodiment
Formula：Emamectin-benzoate 1kg, Rynaxypyr 8kg, dispersant T36 0.25kg, dispersion
It is agent FD 1.6kg, emulsifier tween 80 2.65kg, wetting agent IGEBAL BC/10 (Rhodia) 0.46kg, cyanurotriamide modified
Lauxite 13.875kg, xanthans：0.1kg, organic silicon defoamer 0.2kg, pH adjusting agent：In right amount, water complements to 100kg
Preparation process：
Emamectin-benzoate micro-capsule suspension, the 80kg that 12.5kg is prepared according to 1 method of embodiment
The Rynaxypyr microcapsule suspending agent prepared according to 2 method of embodiment is mixed evenly, and adds remaining xanthans and defoaming
Agent, benefit add water to 100kg and are uniformly mixed to get to 9% emamectin benzoate Rynaxypyr microcapsule suspending agent.
Embodiment 5：10% emamectin benzoate Rynaxypyr microcapsule suspending agent
Formula：Emamectin-benzoate 5kg, Rynaxypyr 5kg, dispersant T36 3.25kg, emulsification
Agent Tween 80 1.25kg, wetting agent IGEBAL BC/10 (Rhodia) 0.5kg, cyanurotriamide modified urea resin 9.4kg, it is yellow
Virgin rubber：0.1Kg, antifoaming agent 0.2kg, pH adjusting agent：In right amount, water complements to 100kg.
Preparation process：
1. the preparation of Rynaxypyr fine suspension：By Rynaxypyr 5kg, dispersant T36 2kg, IGEBAL
BC/10 (Rhodia) 0.2kg, antifoaming agent 0.75kg, xanthans 0.038kg, water 29.5kg, are ground to after mixing using sand mill
Grain size D90 ＜ 2um, obtain the fine suspension A of active component.
2. by step 1. in obtained Rynaxypyr micro suspension agent 37.5kg be added to and prepared according to 1 method of embodiment
62.5kg emamectin benzoate microcapsule suspending agents in stir evenly, mixing speed be 300 revs/min, that is, arrive
A kind of 10% novel emamectin benzoate Rynaxypyr microcapsule suspending agent.
Emamectin-benzoate is in microcapsules state, chlorine worm benzene first in microcapsule suspending agent in the present embodiment
Amide is in suspending agent state, and said preparation more can effectively play emamectin-benzoate and Rynaxypyr
Action character, the characteristics of giving full play to Rynaxypyr quick-acting and strong absorbability, while effective protection methylamino Avermectin
Plain benzoate is not illuminated by the light decomposition, extends the lasting period of emamectin-benzoate.
For a further understanding of the present invention, with reference to Application Example, the present invention is described in detail.
Embodiment 6
Below to right after emamectin-benzoate and Rynaxypyr single active ingredient and the two compounding
Rice-stem borer control effect is tested, and specific implementation mode is as follows：
Test pesticide：8% emamectin benzoate microcapsule suspending agent, 10% Rynaxypyr microcapsule suspension
Agent, 5% emamectin benzoate Rynaxypyr microcapsule suspending agent, 9% emamectin benzoate Rynaxypyr microcapsule suspending agent, 10% first
Tie up salt Rynaxypyr microcapsule suspending agent.
Comparison medicament：2.3% emamectin-benzoate missible oil, 200 grams per liter Rynaxypyr suspending agents,
5% emamectin benzoate Rynaxypyr suspending agent, 9% emamectin benzoate Rynaxypyr suspending agent, 10% emamectin benzoate chlorine worm
Benzamide suspending agent.
5% emamectin benzoate Rynaxypyr suspending agent of comparison medicament used in the present invention, 9% emamectin benzoate chlorine worm benzene
Formamide suspending agent, 10% emamectin benzoate Rynaxypyr suspending agent, preparation method are as follows：
5% emamectin benzoate Rynaxypyr suspending agent formula：Emamectin-benzoate 2kg, chlorine worm benzene first
Amide 3kg, dispersant T36 2kg, wetting agent IGEBAL BC/10 (Rhodia) 0.5kg, aluminium-magnesium silicate：1kg, ethylene glycol 5kg,
Xanthans：0.1kg, antifoaming agent 0.2kg, sodium benzoate 0.2kg, water complement to 100kg.
9% emamectin benzoate Rynaxypyr suspending agent formula：Emamectin-benzoate 1kg, chlorine worm benzene first
Amide 8kg, dispersant T36 2kg, wetting agent IGEBAL BC/10 (Rhodia) 0.5kg, aluminium-magnesium silicate：1kg, ethylene glycol
5kg, xanthans：0.1kg, antifoaming agent 0.2kg, sodium benzoate 0.2kg, water complement to 100kg.
10% emamectin benzoate Rynaxypyr suspending agent formula：Emamectin-benzoate 5kg, chlorine worm benzene first
Amide 5kg, dispersant T36 2kg, wetting agent IGEBAL BC/10 (Rhodia) 0.5kg, aluminium-magnesium silicate：1kg, ethylene glycol
5kg, xanthans：0.1kg, antifoaming agent 0.2kg, sodium benzoate 0.2kg, water complement to 100kg.
Preparation process：Proportionally by deionized water, dispersant wetting agent, it is pumped into the configuration for being equipped with high shear agitation machine
In kettle, stirring is opened to being completely dissolved.Active compound is added to continue to shear half an hour.Configuration is proportionally added in other auxiliary materials
In kettle, continue shearing 45 minutes.It opens two-stage to be sanded, controls discharging speed.Detection grain size, suspensibility and other indexs such as contain
Amount, pH, proportion, pourability.It can be packed after qualification, as a contrast medicament.
Controlling object:Rice-stem borer
Environmental condition：Experiment is located at Huai'an Hongze County, and experimental plot cultivation and fertilizer and water management etc. are consistent, and rice is planted
Training kind is Huaihe River rice No. 5.
Experimental design：Experiment sets 11 processing altogether, each handles 4 repetitions, totally 44 cells, each plot area 20 are flat
Square rice, each cell random alignment.11 processing are respectively：(1) 5% emamectin benzoate Rynaxypyr microcapsule suspending agent, (2)
5% emamectin benzoate Rynaxypyr suspending agent, (3) 9% emamectin benzoate Rynaxypyr microcapsule suspending agents, (4) 9% first dimension
Salt Rynaxypyr suspending agent, (5) 10% emamectin benzoate Rynaxypyr microcapsule suspending agents, (6) 10% emamectin benzoates
Rynaxypyr suspending agent, (7) 8% emamectin benzoate microcapsule suspending agents, (8) 10% Rynaxypyrs
Microcapsule suspending agent, (9) 2.3% emamectin-benzoate missible oil, (10) 200 grams per liter Rynaxypyr suspending agents,
(11) clear water compares.
Test method：In the 1st dispenser of striped rice borer egg hatching peak, test medicine is total to dispenser 1 time；Comparison medicament is in first
Dispenser 1 time again after secondary dispenser 7 days, altogether dispenser 2 times.(it is sprayed using Singapore's profit agriculture Jacto 16LITROS type sprayers, aperture
＜ 7mm, medicament do not stay raffinate), it is watered 1.5 kilograms of cauline leaf even sprayings per cell.
Investigation method：It 15 days after the 1st dispenser, 30 days, 45 days, is sampled using parallel great-jump-forward, per cell tune
50 clumps of rice are looked into, withered calculation is recorded, calculate withered heart rate and preventive effect.
Drug effect computational methods：
The withered calculation of withered heart rate (%)=borer pest/investigation total strain number × 100
Control effect (%)=(check plot withered heart rate-treatment region withered heart rate)/check plot withered heart rate × 100
It the results are shown in Table 1.
Control effect of 1 reagent agent of table to rice-stem borer
Note：Compared using Duncan ' s duncan's new multiple range methods in DPS softwares, 5% level of signifiance of lowercase letter.
As it can be seen from table 1 8% emamectin benzoate microcapsule suspending agent, 10% Rynaxypyr are micro-
Capsule suspending agent, 5% emamectin benzoate Rynaxypyr microcapsule suspending agent, 9% emamectin benzoate Rynaxypyr microcapsule suspending agent,
Rice-stem borer control effect is used in 10% emamectin benzoate Rynaxypyr microcapsule suspending agent medication 1 time with comparison medicament respectively
The control effect that medicine is 2 times is quite or better than control single dose.
Therefore, emamectin-benzoate and Rynaxypyr single active ingredient or two in production practice
Person, which is used in combination, makes microcapsule suspending agent, the characteristics of Rynaxypyr quick-acting and strong absorbability can be given full play to and
Effective protection emamectin-benzoate is not illuminated by the light decomposition, extends the holding effect of emamectin-benzoate
Phase significantly improves rice-stem borer control effect；Spraying times are reduced simultaneously, reduce drug cost.
Embodiment 7
Rice-stem borer picks up from the rice terrace of Huaian Hongze County, the striped rice borer pieces of an egg acquired from field, indoor rice children
Seedling is raised.Rearing conditions:Temperature (25 ± 2) DEG C, relative temperature 80% or so, 16h illumination.Tillering stage rice seedlings are put into foster worm
It lays eggs for rice stem borer in net cage.It will be seeded in wide-mouth bottle after accelerating germination of rice seed, accessed when rice seedling grows up to 5~8cm
Striped rice borer pieces of an egg or larva raising.The Chilo spp larvae in 2 ages is taken to be tested.
Medicament：(1) 2.3% emamectin-benzoate missible oil, (2) 200 grams per liter Rynaxypyrs suspend
Agent, (3) 8% emamectin benzoate microcapsule suspending agents, (4) 10% Rynaxypyr microcapsule suspending agents, (5)
5% emamectin benzoate Rynaxypyr suspending agent, (6) 5% emamectin benzoate Rynaxypyr microcapsule suspending agents, (7) 9% first dimension
Salt Rynaxypyr suspending agent, (8) 9% emamectin benzoate Rynaxypyr microcapsule suspending agents, (9) 10% emamectin benzoate chlorine
Worm benzamide suspending agent (10) 10% emamectin benzoate Rynaxypyr microcapsule suspending agent (11) clear water compares.
Toxicity Determination of the medicament to rice-stem borer：Using dipping seedling method.The rice seedling at 30 days or so the length of time rice seedlings grow is cut
At the rice straw of 15cm or so, a little rice root is stayed in root, cleans and dries, and is taken out after impregnating 10s in the liquid configured, after taking-up
It is placed in naturally dry on filter paper, is put into the teat glass of 3cm × 20cm, tube bottom is put into moisturizing cotton balls.By 2 ages that raising is for use
The access of mid-term larva is placed in the rice seedling test tube of respective concentration processing, is sealed with black cloth, is placed in temperature as 28 ± 1 DEG C, illumination week
The illumination of phase 16h: raising in the constant incubator of 8h dark, inspection result after processing 5 days, is unable to the coordinated movement of various economic factors to touch polypide and is
Death standard.Calculate the death rate and corrected mortality.
Formula (1)：
Formula (2)：
If compareing the death rate<5%, without correction；If 5%≤control the death rate≤20%, should carry out school by formula (2)
Just；If compareing the death rate>20%, experiment need to reform.
Data processing is carried out with DPS softwares, calculates regression equation, LC50。
Test result is shown in Table 2
Toxicity test result of 2 reagent agent of table to rice-stem borer
From table 2 it can be seen that emamectin benzoate microcapsule suspending agent and Rynaxypyr microcapsule suspension
Agent is suitable with control single dose respectively to the indoor virulence of rice-stem borer；The two compounding is prepared into microcapsule suspending agent and changes to rice two
The indoor virulence of snout moth's larva respectively with 5% emamectin benzoate Rynaxypyr suspending agent, 9% emamectin benzoate Rynaxypyr suspending agent
It is suitable with 10% emamectin benzoate Rynaxypyr suspending agent.Illustrate emamectin-benzoate and Rynaxypyr
Single active ingredient or the two, which are used in combination, makes microcapsule suspending agent, can effectively play pesticide activity component to rice-stem borer
Insecticidal effect.
Embodiment 8
Below to right after emamectin-benzoate and Rynaxypyr single active ingredient and the two compounding
Rice leaf roller control effect is tested, and specific implementation mode is as follows：
Test pesticide：8% emamectin benzoate microcapsule suspending agent, 10% Rynaxypyr microcapsule suspension
Agent, 5% emamectin benzoate Rynaxypyr microcapsule suspending agent, 9% emamectin benzoate Rynaxypyr microcapsule suspending agent, 10% first
Tie up salt Rynaxypyr microcapsule suspending agent.
Comparison medicament：2.3% emamectin-benzoate missible oil, 200 grams per liter Rynaxypyr suspending agents,
5% emamectin benzoate Rynaxypyr suspending agent, 9% emamectin benzoate Rynaxypyr suspending agent, 10% emamectin benzoate chlorine worm
Benzamide suspending agent.
Controlling object:Rice leaf roller
Environmental condition：Experiment is located at Huai'an Hongze County, and experimental plot cultivation and fertilizer and water management etc. are consistent, and rice is planted
Training kind is Huaihe River rice No. 5.
Experimental design：Experiment sets 11 processing altogether, each handles 4 repetitions, totally 44 cells, each plot area 20 are flat
Square rice, each cell random alignment.11 processing are respectively：(1) 5% emamectin benzoate Rynaxypyr microcapsule suspending agent, (2)
5% emamectin benzoate Rynaxypyr suspending agent, (3) 9% emamectin benzoate Rynaxypyr microcapsule suspending agents, (4) 9% first dimension
Salt Rynaxypyr suspending agent, (5) 10% emamectin benzoate Rynaxypyr microcapsule suspending agents, (6) 10% emamectin benzoates
Rynaxypyr suspending agent, (7) 8% emamectin benzoate microcapsule suspending agents, (8) 10% Rynaxypyrs
Microcapsule suspending agent, (9) 2.3% emamectin-benzoate missible oil, (10) 200 grams per liter Rynaxypyr suspending agents,
(11) clear water compares.
Test method：It tests and incubates peak period dispenser in Eggs of The Rice Leaf Roller, dispenser is primary (to use Singapore profit agriculture Jacto
16LITROS type sprayers are sprayed, and aperture ＜ 7mm, medicament does not stay raffinate), 1.5 kilograms of cauline leaf even sprayings are watered per cell, are applied
Field keeps the water layer 5d of 3cm when medicine, falls after doing and pours water again naturally.
Investigation method：15 days after dispenser, when check plot damage symptoms are apparent, sampled using parallel great-jump-forward, per cell
50 clumps of rice are investigated, leaf roll number is recorded, calculate leaf roll rate and preventive effect.
Drug effect computational methods：
Leaf roll rate (%)=investigation leaf roll number/investigation total number of sheets × 100
Control effect (%)=(check plot leaf roll rate-treatment region leaf roll rate)/check plot leaf roll rate × 100
It the results are shown in Table 3.
Control effect of 3 reagent agent of table to rice leaf roller
Note：Compared using Duncan ' s duncan's new multiple range methods in DPS softwares, 5% level of signifiance of lowercase letter
From table 3 it can be seen that 8% emamectin benzoate microcapsule suspending agent, 10% Rynaxypyr are micro-
Capsule suspending agent, 5% emamectin benzoate Rynaxypyr microcapsule suspending agent, 9% emamectin benzoate Rynaxypyr microcapsule suspending agent,
10% emamectin benzoate Rynaxypyr microcapsule suspending agent medication 1 time to paddy rice rice leaf roller control effect respectively with comparison medicine
The control effect that agent medication is 2 times is quite or better than control single dose.
Therefore, emamectin-benzoate and Rynaxypyr single active ingredient or two in production practice
Person, which is used in combination, makes microcapsule suspending agent, the characteristics of Rynaxypyr quick-acting and strong absorbability can be given full play to and
Effective protection emamectin-benzoate is not illuminated by the light decomposition, extends the holding effect of emamectin-benzoate
Phase significantly improves paddy rice rice leaf roller control effect；Spraying times are reduced simultaneously, reduce drug cost.
Embodiment 9
Rice leaf roller picks up from the rice terrace of Huaian Hongze County, indoor rice seedling raising mostly generation.Rearing conditions:Temperature
It spends (25 ± 2) DEG C, relative temperature 80% or so, 16h illumination.It will be seeded in wide-mouth bottle after accelerating germination of rice seed, wait for that rice seedling is long
At access Eggs of The Rice Leaf Roller or larva raising when 5~8cm.The rice leaf roller larvae in 2 ages is taken to be tested.
Medicament：(1) 2.3% emamectin-benzoate missible oil, (2) 200 grams per liter Rynaxypyrs suspend
Agent, (3) 8% emamectin benzoate microcapsule suspending agents, (4) 10% Rynaxypyr microcapsule suspending agents, (5)
5% emamectin benzoate Rynaxypyr suspending agent, (6) 5% emamectin benzoate Rynaxypyr microcapsule suspending agents, (7) 9% first dimension
Salt Rynaxypyr suspending agent, (8) 9% emamectin benzoate Rynaxypyr microcapsule suspending agents, (9) 10% emamectin benzoate chlorine
Worm benzamide suspending agent (10) 10% emamectin benzoate Rynaxypyr microcapsule suspending agent (11) clear water compares.
Toxicity Determination of the medicament to rice leaf roller：Using dipping seedling method.Tillering stage rice leaf is won, by water
Rice blade impregnates 10s in the reagent agent configured, and taking-up is placed on naturally dry on filter paper, is put into the glass of 3cm × 20cm
In glass test tube, tube bottom is put into moisturizing cotton balls.The for use 1 age mid-term larva access of raising is placed with to the Rice Leaf of respective concentration processing
It in piece test tube, is sealed with black cloth, it is 25 ± 2 DEG C, periodicity of illumination 16h illumination to be placed in temperature: being raised in the constant incubator of 8h dark
It supports, handles inspection result after 48h, the coordinated movement of various economic factors is unable to as death standard to touch polypide.Calculate the death rate and corrected mortality.
Formula (1)：
Formula (2)：
If compareing the death rate<5%, without correction；If 5%≤control the death rate≤20%, should carry out school by formula (2)
Just；If compareing the death rate>20%, experiment need to reform.
Data processing is carried out with DPS softwares, calculates regression equation, LC50。
Test result is shown in Table 4
Toxicity test result of 4 reagent agent of table to rice leaf roller
From table 4, it can be seen that emamectin benzoate microcapsule suspending agent and Rynaxypyr microcapsule suspension
Agent is suitable with control single dose respectively to the indoor virulence of paddy rice rice leaf roller；It is vertical to rice that the two compounding is prepared into microcapsule suspending agent
The indoor virulence of leaf roll snout moth's larva is outstanding with 5% emamectin benzoate Rynaxypyr suspending agent, 9% emamectin benzoate Rynaxypyr respectively
Floating agent and 10% emamectin benzoate Rynaxypyr suspending agent are suitable.Illustrate emamectin-benzoate and chlorine worm benzene first
Amide single active ingredient or the two, which are used in combination, makes microcapsule suspending agent, can effectively play pesticide activity component to cnaphalocrocis
The insecticidal effect of snout moth's larva.
The explanation of above example is only intended to facilitate the understanding of the method and its core concept of the invention.It should be pointed out that pair
For those skilled in the art, without departing from the principle of the present invention, the present invention can also be carried out
Some improvements and modifications, these improvement and modification are also fallen within the protection scope of the claims of the present invention.
In present specification, emamectin-benzoate also abbreviation emamectin benzoate.
Claims (10)
1. a kind of microcapsule suspending agent, which is characterized in that be mainly grouped as by the group of following weight ratio：Pesticide active ingredient 0.5%-
30%, cyst material 1%-20%, emulsifier 1%-5%, dispersant 1%-5%, wetting agent 0.1%-3%, pH adjusting agent
0.1%-5%, thickener 0.05%-0.3%, antifoaming agent 0.1%-0.2%, water complement to 100%；The cyst material choosing
From：Lauxite, polyureas, polyisocyanates, gelatin, Arabic gum, melamine resin or melamine modified urea-formaldehyde
One or more combination in resin；
The pesticide active ingredient is in Rynaxypyr and/or emamectin-benzoate or avermectin
One kind；
The emulsifier is selected from：Fatty alcohol polyoxyethylene ether, alkyl phenol polyoxyethylene ether, cardanol polyoxyethylene ether, castor-oil plant
Oily polyoxyethylene ether, tween, this disk, calcium dodecyl benzene sulfonate, agriculture breast 600#, agriculture breast 1601#, agriculture breast 1602#, Nongru-700 #
In it is one or more；
The dispersant is selected from：Aliphatic alcohol polyoxyvinethene phosphate, polycarboxylate salt dispersant, EO-PO block polyethers or alkane
Base naphthalene sulfonate；
The wetting agent is selected from：Lauryl sodium sulfate, fatty alcohol polyoxyethylene ether sulfate, alkylnaphthalene sulfonate, fat
Alcohol polyoxyethylene ether, SOPA-270, disecoctylmaleate sodium sulfonate；
The pH adjusting agent is selected from：One kind in hydrochloric acid, glacial acetic acid, ammonium chloride, ethylenediamine, triethylamine or triethanolamine or
Arbitrary several combinations；
The thickener is selected from：Xanthans, polyvinyl alcohol 1788, Macrogol 4000, Macrogol 6000, aluminium-magnesium silicate,
Or lithium magnesium silicate；
The antifoaming agent is selected from：The mixing of the antifoaming agent of one or both of organic silicon defoamer, polyether antifoam agent type
Object.
2. microcapsule suspending agent according to claim 1, which is characterized in that the pesticide active ingredient be selected from methylamino Ah
Tie up rhzomorph benzoate and Rynaxypyr or avermectin and Rynaxypyr, preferably emamectin benzoate benzene first
The weight percentage of hydrochlorate or avermectin in the microcapsule suspending agent is 1%-10%, and Rynaxypyr is described
Microcapsule suspending agent in weight percentage be 1%-20%.
3. microcapsule suspending agent according to claim 2, which is characterized in that the cyst material is Lauxite, trimerization
Cyanamide formaldehyde resin or cyanurotriamide modified urea resin.
4. microcapsule suspending agent according to any one of claim 1-3, which is characterized in that the agriculture of the microcapsule suspending agent
When pharmaceutically active ingredient is single active ingredient emamectin-benzoate, avermectin or Rynaxypyr, pass through
It is prepared by micro capsule technology；The pesticide active ingredient is two kinds of active components emamectin-benzoate and chlorine
When worm benzamide or avermectin and Rynaxypyr, it can be obtained by following three kinds of different methods described micro-
1. capsule suspending agent prepares microcapsule suspending agent using a kind of technique simultaneously after two kinds of ingredient mixing living, 2. two kinds of active components use
Different technique remixes the microcapsule formulation uniformly compounded after preparing microcapsule suspending agent respectively, 3. one in two kinds of active components
Kind prepares microcapsule suspending agent by micro capsule technology, and another ingredient is prepared into suspending agent using grinding technics, and the two remixes
Uniformly obtain the microcapsule suspending agent.
5. microcapsule suspending agent according to claim 4, which is characterized in that the preparation process of microcapsule suspending agent is that micro suspension is former
Position polymerization.
6. microcapsule suspending agent according to claim 5, which is characterized in that the micro suspension situ aggregation method prepares work
Skill is：
(1) preparation of fine suspension：By pesticide active principle, wetting agent, dispersant, emulsifier, antifoaming agent and a certain amount of water
Grain size D90 ＜ 2um are ground to using sand mill after mixing, obtain the fine suspension A of active component；
(2) preparation of cyst material performed polymer：By formaldehyde and urea or melamine and formaldehyde or melamine, formaldehyde
It is stirred evenly with urea, 200-300 revs/min of rotating speed, and aqueous slkali is added and adjusts pH=8-9, be warming up to 70 DEG C, keep the temperature 1h,
Obtain cyst material prepolymer solution B；
(3) preparation of microcapsules：Obtained cyst material prepolymer solution B is added in suspending liquid A, 1000-1500 revs/min
High-speed stirred is uniform；Mixing speed is reduced to 500-600 revs/min, pH adjusting agent regulation system pH to 2.5-4.5 catalysis is added
Encystation polymerisation occurs；It is 200-300 revs/min to gradually reduce rotating speed, and is gradually warming up to 40-60 DEG C of solidification cyst wall, until
PH adjusting agent is added after reaction end, system pH is adjusted to neutrality, thickener and remaining water is added, stirs evenly up to described
Microcapsule suspending agent.
7. microcapsule suspending agent according to claim 1, which is characterized in that two kinds of ingredients compoundings of the microcapsule suspending agent and
When the non-micro-capsule of one of which ingredient, preparation method is to be added in the microcapsule suspending agent prepared by claim 6 another
The suspending agent liquid of kind active constituent, the microcapsule suspending agent of different conditions is in by being uniformly mixing to obtain two kinds of active components.
8. the preparation method of the microcapsule suspending agent described in claim 1-3, which is characterized in that comprise the steps of：Described is micro-
The pesticide active ingredient of capsule suspending agent is single active ingredient emamectin-benzoate, avermectin or chlorine worm benzene first
When amide, prepared by micro capsule technology；The pesticide active ingredient is two kinds of active components emamectin benzoate
When benzoate and Rynaxypyr or avermectin and Rynaxypyr, following three kinds of different methods can be passed through
The microcapsule suspending agent is obtained, it is outstanding 1. to prepare micro-capsule using a kind of micro suspension situ aggregation method simultaneously after two kinds of ingredient mixing living
Agent is floated, 2. two kinds of active components remix the micro-capsule uniformly compounded after preparing microcapsule suspending agent respectively using different technique
Preparation, 3. one kind preparing microcapsule suspending agent by micro suspension situ aggregation method in two kinds of active components, and another ingredient use is ground
Grinding process is prepared into suspending agent, and the two, which remixes, uniformly obtains the microcapsule suspending agent.
9. preparation method according to claim 8, it is characterised in that the preparation method includes：
(1) preparation of fine suspension：By pesticide active principle, wetting agent, dispersant, emulsifier, antifoaming agent and a certain amount of water
Grain size D90 ＜ 2um are ground to using sand mill after mixing, obtain the fine suspension A of active component；
(2) preparation of cyst material performed polymer：It will be in formaldehyde and urea or melamine and formaldehyde or melamine, first
Aldehyde and urea stir evenly, 200-300 revs/min of rotating speed, and aqueous slkali is added and adjusts pH=8-9, are warming up to 70 DEG C, heat preservation
1h obtains cyst material prepolymer solution B；
(3) preparation of microcapsules：Obtained cyst material prepolymer solution B is added in suspending liquid A, 1000-1500 revs/min
High-speed stirred is uniform；Mixing speed is reduced to 500-600 revs/min, pH adjusting agent regulation system pH to 2.5-4.5 catalysis is added
Encystation polymerisation occurs；It is 200-300 revs/min to gradually reduce rotating speed, and is gradually warming up to 40-60 DEG C of solidification cyst wall, until
PH adjusting agent is added after reaction end, system pH is adjusted to neutrality, thickener and remaining water is added, stirs evenly up to described
Microcapsule suspending agent.
10. the microcapsule suspending agent described in any one of claim 1-3 is in the insect pest for preventing veterinary antibiotics, field crop
Using.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810259345.7A CN108432751A (en) | 2018-03-27 | 2018-03-27 | A kind of pesticide microcapsule suspending agent and its preparation method and application |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810259345.7A CN108432751A (en) | 2018-03-27 | 2018-03-27 | A kind of pesticide microcapsule suspending agent and its preparation method and application |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN108432751A true CN108432751A (en) | 2018-08-24 |
Family
ID=63196951
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201810259345.7A Pending CN108432751A (en) | 2018-03-27 | 2018-03-27 | A kind of pesticide microcapsule suspending agent and its preparation method and application |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN108432751A (en) |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111493075A (en) * | 2020-05-09 | 2020-08-07 | 上海明德立达生物科技有限公司 | Butachlor-oxadiargyl microcapsule suspending agent, preparation method and application thereof |
| CN112841184A (en) * | 2021-01-28 | 2021-05-28 | 常州大学 | Physcion microcapsule sustained release agent and preparation method thereof |
| CN113016815A (en) * | 2021-02-23 | 2021-06-25 | 沈阳化工大学 | Abamectin B2 microcapsule suspending agent and preparation method thereof |
| CN113519545A (en) * | 2021-07-15 | 2021-10-22 | 孟州市华丰生化农药有限公司 | Thiamethoxam microcapsule seed treatment suspending agent and application thereof |
| CN115211428A (en) * | 2021-09-14 | 2022-10-21 | 山东统防生物科技有限公司 | Fluopicolide/dimethomorph composition as well as preparation method and application thereof |
| CN116035017A (en) * | 2022-10-08 | 2023-05-02 | 南通江山农药化工股份有限公司 | Prochloraz-flumioxazin microcapsule suspending agent and preparation method thereof |
Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2007039055A2 (en) * | 2005-09-19 | 2007-04-12 | Sipcam S.P.A. | Formulations based on 3 -iodo- 2 -propynyl butyl carbamate |
| CN101548680A (en) * | 2009-04-23 | 2009-10-07 | 惠州市中迅化工有限公司 | Pesticidal composition containing emamectin benzoate and chlorantraniliprole |
| CN102239861A (en) * | 2011-08-22 | 2011-11-16 | 谭晓辉 | Abamectin and thiazoline complex microcapsule suspension and preparation method thereof |
| CN104430394A (en) * | 2014-10-20 | 2015-03-25 | 广西大学 | Preparation method of ivermectin/emamectin benzoate compound microcapsule suspension |
| CN105724389A (en) * | 2016-04-19 | 2016-07-06 | 陕西上格之路生物科学有限公司 | Dispersible oil suspension containing chlorantraniliprole |
| CN106561640A (en) * | 2016-11-07 | 2017-04-19 | 北京明德立达农业科技有限公司 | Micro-capsule suspension-suspending agent containing abamectin and etoxazole and preparation method of micro-capsule suspension-suspending agent |
| CN107279150A (en) * | 2017-05-26 | 2017-10-24 | 北京明德立达农业科技有限公司 | A kind of microcapsule suspension suspending agent of containing chlorantraniliprole and AVM and preparation method thereof |
-
2018
- 2018-03-27 CN CN201810259345.7A patent/CN108432751A/en active Pending
Patent Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2007039055A2 (en) * | 2005-09-19 | 2007-04-12 | Sipcam S.P.A. | Formulations based on 3 -iodo- 2 -propynyl butyl carbamate |
| CN101548680A (en) * | 2009-04-23 | 2009-10-07 | 惠州市中迅化工有限公司 | Pesticidal composition containing emamectin benzoate and chlorantraniliprole |
| CN102239861A (en) * | 2011-08-22 | 2011-11-16 | 谭晓辉 | Abamectin and thiazoline complex microcapsule suspension and preparation method thereof |
| CN104430394A (en) * | 2014-10-20 | 2015-03-25 | 广西大学 | Preparation method of ivermectin/emamectin benzoate compound microcapsule suspension |
| CN105724389A (en) * | 2016-04-19 | 2016-07-06 | 陕西上格之路生物科学有限公司 | Dispersible oil suspension containing chlorantraniliprole |
| CN106561640A (en) * | 2016-11-07 | 2017-04-19 | 北京明德立达农业科技有限公司 | Micro-capsule suspension-suspending agent containing abamectin and etoxazole and preparation method of micro-capsule suspension-suspending agent |
| CN107279150A (en) * | 2017-05-26 | 2017-10-24 | 北京明德立达农业科技有限公司 | A kind of microcapsule suspension suspending agent of containing chlorantraniliprole and AVM and preparation method thereof |
Non-Patent Citations (1)
| Title |
|---|
| 梁治齐 等: "《微胶囊技术及其应用》", 30 April 1994, 中国轻工业出版社 * |
Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111493075A (en) * | 2020-05-09 | 2020-08-07 | 上海明德立达生物科技有限公司 | Butachlor-oxadiargyl microcapsule suspending agent, preparation method and application thereof |
| CN111493075B (en) * | 2020-05-09 | 2021-03-02 | 上海明德立达生物科技有限公司 | Butachlor-oxadiargyl microcapsule suspending agent, preparation method and application thereof |
| CN112841184A (en) * | 2021-01-28 | 2021-05-28 | 常州大学 | Physcion microcapsule sustained release agent and preparation method thereof |
| CN113016815A (en) * | 2021-02-23 | 2021-06-25 | 沈阳化工大学 | Abamectin B2 microcapsule suspending agent and preparation method thereof |
| CN113519545A (en) * | 2021-07-15 | 2021-10-22 | 孟州市华丰生化农药有限公司 | Thiamethoxam microcapsule seed treatment suspending agent and application thereof |
| CN115211428A (en) * | 2021-09-14 | 2022-10-21 | 山东统防生物科技有限公司 | Fluopicolide/dimethomorph composition as well as preparation method and application thereof |
| CN115211428B (en) * | 2021-09-14 | 2024-03-08 | 山东统防生物科技有限公司 | Fluopicolide-dimethomorph composition and preparation method and application thereof |
| CN116035017A (en) * | 2022-10-08 | 2023-05-02 | 南通江山农药化工股份有限公司 | Prochloraz-flumioxazin microcapsule suspending agent and preparation method thereof |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN108432751A (en) | A kind of pesticide microcapsule suspending agent and its preparation method and application | |
| CN107836461A (en) | Eco-friendly pesticide missible oil | |
| CN101352167B (en) | Pesticide composition based on nitenpyram | |
| CN103004825A (en) | Microcapsule suspension-suspending agent containing diafenthiuron and preparation method thereof | |
| BR112020002933A2 (en) | oil-based concentrate, its preparation method and its use | |
| CN107232225A (en) | A kind of microcapsules suspension suspending agent containing gamma cyhalothrin and sulfoxaflor and preparation method thereof | |
| AU2021100104A4 (en) | Microcapsule suspension of pesticide and preparation method and use thereof | |
| CN105340911A (en) | Pesticide composition as well as preparation method and application thereof | |
| JP2002521405A (en) | Cadusaphos microencapsulated formulation | |
| CN105638715B (en) | A kind of agricultural pesticide composition and application thereof | |
| CN105831147B (en) | A kind of agricultural pesticide composition containing sulphur insect amide and lambda-cyhalothrin and application thereof | |
| CN105613511B (en) | A kind of agricultural pesticide composition and application thereof | |
| CN105746567B (en) | A kind of agricultural pesticide composition and application thereof | |
| CN109362753A (en) | A kind of Pesticidal combination containing emamectin-benzoate | |
| CN104522041A (en) | Flonicamid and efficient cyhalothrin containing insecticide composition | |
| CN107333770A (en) | A kind of miticide composition containing fluorine pyrrole furanone and bromine cyanogen insect amide | |
| CN105766989B (en) | A kind of agricultural pesticide composition containing sulphur insect amide and cyfloxylate and application thereof | |
| CN108077273A (en) | A kind of miticide composition containing second azoles mite nitrile and Amitraz | |
| CN108184857A (en) | A kind of miticide composition containing second azoles mite nitrile with single carbonamidine | |
| CN105685067B (en) | A kind of agricultural pesticide composition and application thereof | |
| CN105707119B (en) | A kind of agricultural pesticide composition containing sulphur insect amide and chlopyrifos and application thereof | |
| CN105660681A (en) | Agricultural insecticide composition containing insect sulfamide and fenpropathrin and application thereof | |
| CN105660649B (en) | A kind of agricultural pesticide composition and application thereof | |
| CN105660680B (en) | A kind of agricultural pesticide composition containing sulphur insect amide and Diacloden and application thereof | |
| CN105685050B (en) | A kind of agricultural pesticide composition and application thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20180824 |
|
| RJ01 | Rejection of invention patent application after publication |