CN103004825A - Microcapsule suspension-suspending agent containing diafenthiuron and preparation method thereof - Google Patents
Microcapsule suspension-suspending agent containing diafenthiuron and preparation method thereof Download PDFInfo
- Publication number
- CN103004825A CN103004825A CN201110286577XA CN201110286577A CN103004825A CN 103004825 A CN103004825 A CN 103004825A CN 201110286577X A CN201110286577X A CN 201110286577XA CN 201110286577 A CN201110286577 A CN 201110286577A CN 103004825 A CN103004825 A CN 103004825A
- Authority
- CN
- China
- Prior art keywords
- diafenthiuron
- active component
- microcapsules
- suspending agent
- microcapsule suspension
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Abstract
The invention relates to a microcapsule suspension-suspending agent containing diafenthiuron and a preparation method thereof. The pesticide microcapsule suspension-suspending agent is composed of, by weight percent, 5 to 40 % of a first active component diafenthiuron, 10 to 75 % of a second active component microcapsule, 5 to 20 % of an auxiliary agent and the balance being water, wherein the microcapsule contains the second active components. According to the invention, the second active components are made into the microcapsule, and the diafenthiuron is in a suspension form, thereby reducing adverse effects between the two components, relatively well playing synergistic effects of compound pesticides, achieving purposes of stable storage, long-lasting pesticide effect, high bioavailability and good control effect, and being widely used as pesticide preparations for prevention and treatment of various diseases and insects.
Description
Technical field
The invention belongs to technical field of pesticide preparations, be specifically related to a kind of microcapsule suspension-suspending agent that contains diafenthiuron and preparation method thereof.
Background technology
Diafenthiuron (Diafenthiuron), chemical name: 1-tertiary butyl-3-(2,6-diisopropyl-4-Phenoxyphenyl) thiocarbamide.The diafenthiuron structural formula is as follows:
Diafenthiuron is a kind of novel Thiourea efficient insecticide, miticide, have tag, stomach poison function and good osmosis, insecticidal mechanism is unique, under UV-irradiation or in insect, evil mite body, be decomposed into a kind of noxious material that hinders the function of insect, evil mite nerve cell Mitochondria under the effect of mixed-functional oxidase, affect its respiration and power conversion, make insect ossified.Diafenthiuron has stronger activity to having produced serious drug-fast insect on the vegetables, can prevent and treat aphid, aleyrodid, leafhopper, noctuidae pests and evil mite on various crop and the ornamental plants.
Some pesticide research, manufacturing enterprise carry out diafenthiuron and another active component composite at present, embody preferably synergistic function, and have corresponding preparation method to produce its missible oil (being called for short EC) but the regular dosage forms such as wet-milling (being called for short WP), aqueous suspension agent (being called for short SC).But in actual production, it is poor that the mixture preparation of diafenthiuron and most of agricultural chemicals exists bin stability, and resolution ratio is high, the unsettled problem of drug effect.Be alkalescent when diafenthiuron and most of pesticide activity component are mixed on the one hand, cause product to store the resolution ratio height, affected the quality of product; On the other hand, owing to diafenthiuron plays a role under UV-irradiation, and many another kind of active component under ultraviolet light very easily decomposition composite with diafenthiuron can not be given full play to synergistic effect, have reduced the control efficiency of product.
Summary of the invention
In view of this, provide a kind of stable storage, lasting medicine, bioavailability are high, control efficiency is good contains microcapsule suspension-suspending agent of diafenthiuron and preparation method thereof.
A kind of agricultural chemicals microcapsule suspension-suspending agent that contains diafenthiuron, it is comprised of the first active component diafenthiuron, the second active component microcapsules, auxiliary agent and water, and the weight percentage of each component is:
Described the second active component microcapsules are the microcapsules that contain the second active component.
And, a kind of agricultural chemicals microcapsule suspension that contains diafenthiuron-suspending agent preparation method, it comprises the steps:
Make the second active component microcapsules by the second active component, cyst material and auxiliary agent;
The former medicine of diafenthiuron is fully mixed, disperses with first's auxiliary agent and water, sand milling again, obtain diafenthiuron suspension, in described suspension, add the second active component microcapsules and the second portion auxiliary agent that makes, mix and disperse, obtain containing the agricultural chemicals microcapsule suspension-suspending agent of diafenthiuron, wherein adopt each component and the content of above-mentioned weight percentage meter in each step.
Above-mentioned microcapsule suspension-suspending agent that contains diafenthiuron and preparation method thereof is by existing another kind of active component such as active component Avermectin, emamectin-benzoate, beta-cypermethrin, phoxim etc. with microencapsulation form, and diafenthiuron is suspended form, thereby reduced harmful effect between two kinds of active components, and ultraviolet ray etc. is to the harmful effect of product, the better synergistic function between the performance Recompounded pesticide reaches stable storage, lasting medicine, bioavailability is high, control efficiency is good purpose.
Embodiment
In order to make purpose of the present invention, technical scheme and advantage clearer, below in conjunction with embodiment, the present invention is further elaborated.Should be appreciated that specific embodiment described herein only in order to explain the present invention, is not intended to limit the present invention.
Agricultural chemicals microcapsule suspension-the suspending agent that contains diafenthiuron of the embodiment of the invention (being called for short ZC), it is comprised of the first active component diafenthiuron, the second active component microcapsules, auxiliary agent and water, and the weight percentage of each component is:
Described the second active component microcapsules are the microcapsules that contain the second active component.
Particularly, the second active component can be Avermectin, emamectin-benzoate (being called for short first dimension salt), gamma cyhalothrin, betacyfluthrin, beta-cypermethrin, sumicidin, chlopyrifos, malathion, phoxim or Hostathion.
The content of diafenthiuron is 5%-40%, as previously mentioned, be decomposed into a kind of noxious material that hinders the function of insect, evil mite nerve cell Mitochondria under the effect of diafenthiuron mixed-functional oxidase under UV-irradiation or in insect, evil mite body, affect its respiration and power conversion, make insect ossified.
The second active component microcapsules are for having one of pesticide activity component of following weight percentage in microcapsules: Avermectin 0.5%～15%, emamectin-benzoate 0.5%～10%, gamma cyhalothrin 2.5%～25%, betacyfluthrin 2.5%～10%, beta-cypermethrin 2.5%～16%, sumicidin 2.5%～30%, chlopyrifos 15%～40%, malathion 15%～40%, phoxim 15%～40%, Hostathion 15%～40%.
Particularly, Avermectin belongs to macrolide disaccharide compounds, and it has insects and mites tags and stomach poison function and faint fumigation action is arranged, and residual less at plant surface.
Emamectin-benzoate has the characteristics of super-high-efficient, low toxicity (preparation is closely nontoxic), noresidue, the biopesticide such as nuisanceless, improved 1-3 the order of magnitude with Avermectin comparison insecticidal activity, active high to the larva of lepidopterous insects and other many insects and mite class, existing stomach poison function is double action of contace poison again, at low-down dosage (0.084～2 gram/have good effect under ha), therefore, can adopt lower content in the relative mentioned component of the content of emamectin-benzoate.
Gamma cyhalothrin, betacyfluthrin, beta-cypermethrin and sumicidin all belong to pyrethroid insecticides, wherein gamma cyhalothrin has the effect of walking quickly and keeping away, knocking down and killing to insect, insecticidal spectrum is wide, activity is higher, drug effect is rapid, resistance of rainwater washing against after spraying, and the mechanism of action and sumicidin, flucythrinate are identical, usually and the composite use of other active components, for example be used with the first active component of the present invention.Betacyfluthrin has tags and stomach poison function, and insecticidal spectrum is wide, knocks down rapidly, and the lasting period is long, and plant has good drug resistance to it.The beta-cypermethrin biologically active is higher, it is the efficient isomer of cypermethrin, have and tag and stomach poison function, have insecticidal spectrum wide, knock down fireballing characteristics, insecticidal activity is high than cypermethrin, is applicable to prevent and treat insect and sanitary insect pest on the various plants such as cotton, vegetables, fruit tree, tea tree, forest.The sumicidin insecticidal spectrum is wide, to the natural enemy non-selectivity, take tag and stomach poison function as main, without interior suction and fumigation action, usually cooperate other active components, for example be used with the first active component of the present invention.
Chlopyrifos, malathion, phoxim and Hostathion all belong to organophosphorus insecticide, its Chlorpyrifos insect is had tag, stomach toxicity and fumigation action, especially the control of brown planthopper had extraordinary effect.There is good tagging and certain fumigation action the malathion, and without systemic action, toxicity is low, and the longevity of residure is short, and is all effective to the insect of sucking mouth parts and biting mouthparts.The phoxim insecticidal spectrum is wide, and the power of knocking down is strong, take tag and stomach poison function as main, without systemic action, very effective to the phosphorus wing order larva; Because of to photo-labile, therefore very fast decomposition, cooperates it with the first active component of the present invention, improve its stability in the field.Hostathion has strong tagging and stomach poison function, good disinsection effect, and ovicidal action is obvious, and permeability is stronger, without systemic action, can be used for the various crop such as paddy rice and prevents and treats various pests.
Should be understood that more than just the second active component in the present embodiment is enumerated, the present invention is not limited to above concrete composition, all can be applied in conjunction with design of the present invention with above-mentioned pesticidal preparations close or the phase class.For example, the second active component of the second active component microcapsules also can be the biopesticides such as pleocidin, Celastrus angulatus, nimbin, BT bacillus, can also be other pyrethroid insecticideses such as Biphenthrin, decis, permethrin, cypermethrin, fenpropathrin, ether chrysanthemum ester, cycloprothrin, perhaps other organophosphorus insecticides such as orthene, isocarbophos, flolimat, dichlorvos, Isofenphos methyl, chlorophos, methidathion, Profenofos, diazinon.Because the second active component is microencapsulation form, the first active component diafenthiuron is suspended form, to be come by the cyst wall obstruct of microcapsules between between the compound molecule of two kinds of active components, two kinds of harmful effects between the active component both can have been avoided, can reduce again ultraviolet ray etc. to the harmful effect of product, the better synergistic function between the performance Recompounded pesticide reaches stable storage, lasting medicine, bioavailability is high, control efficiency is good purpose.
Auxiliary agent is any combination of wetting agent, dispersant, thickener, antifreezing agent, mould inhibitor, defoamer or pH value conditioning agent.Be preferably whole combinations in the embodiment of the invention.Wherein, wetting agent preferred fat alcohol APEO, alkyl sulfate or
4894; The preferred lignosulfonates of dispersant, alginate, naphthalene sulfonate,
2500 or polyvinyl alcohol etc.; The preferred silicone defoaming agent of defoamer or alcohol defoaming agent (such as butanols, octanol, isopropyl alcohol); The combination of one or more in the preferred ethylene glycol of antifreezing agent, propane diols, diethylene glycol, the urea; The combination of one or more in the preferred carboxyl alkyl cellulose class of thickener, hydroxy alkyl cellulose, gelatin, xanthans or the aluminium-magnesium silicate; The mould inhibitor preferred sodium benzoate; The combination of one or more in the preferred glacial acetic acid of pH adjusting agent, citric acid or sodium hydroxide, the potassium hydroxide.
Because the present embodiment auxiliary agent adopts above-mentioned whole combination, the auxiliary agent total amount is 5%-20%, there is no particular restriction for the content of every kind of auxiliary agent, and wherein, the content of wetting agent is 0.5%-3%, the content of dispersant is 1%-4%, the content of thickener is 0.1%-0.5%, and the content of antifreezing agent is 4%-8%, and the content of mould inhibitor is 0.1%-0.3%, the content of defoamer is 0.1%-0.8%, and the content of pH value conditioning agent is 0.1%-0.5%.
The average grain diameter of the second active component microcapsules is the 0.1-20 micron, and the embodiment of the invention is preferably the 1-5 micron.Particularly, the raw materials of the second active component microcapsules comprises the component of following percentage by weight: the second active component 0.5%～40%, solvent 2.5%～25%, oiliness cyst material 0%～4%, water-soluble cyst material 0.5%～70%, emulsifier 0.1%～1% and microcapsules auxiliary agent 0.5%～4%, above content is with the microcapsules calculation of total.Solvent can be aromatic solvent, alcoholic solvent or loose base oil.The microcapsules auxiliary agent comprises dispersant, defoamer etc., and dispersant and defoamer can adopt kind above-mentioned and content simultaneously.
The oiliness cyst material can be toluene di-isocyanate(TDI) (TDI), 4, the 4-diphenylmethyl vulcabond (MDI), 1 of washing, the combination of one or more materials in 6-six methylene phenylene diisocyanates (HDI), many methylenes benzene polyisocyanates (PAPI) or aliphatic diisocyanate, aliphatic triisocyanate, the aliphatic polymeric isocyanate; Water-soluble cyst material is the combination of one or more materials in ethylenediamine, propane diamine, diethylene glycol, diethylenetriamine, triethanolamine or urea-formaldehyde resin performed polymer, the melamine resin performed polymer; Solvent can be used hydro carbons, ester class, alcohols, ketone, ethers equal solvent, is preferably the combination of one or more solvents in S-200, S-150, fatty acid methyl ester, loose base oil or methyl alcohol, the ethanol; Emulsifier is various anion, nonionic emulsifier or their combination, preferred farming breast 2201, farming breast 1601, farming breast 601, Tween 80, BY-125 etc.; Dispersant is various dispersants, preferred lignin sulfonate, naphthalenesulfonate, styrene maleic anhydride copolymer, hydroxy alkyl cellulose, alkyl sulfate, polyvinyl alcohol, sodium alginate or gum Arabic etc.; Defoamer can with known defoamer, be preferably silicone defoaming agent or alcohol defoaming agent.In addition, also catalyzer can be added, for example one or more the catalyst combination in hydrochloric acid, ammonium chloride or sodium hydroxide, the potassium hydroxide can be.
Agricultural chemicals microcapsule suspension-the suspending agent that contains diafenthiuron of present embodiment is by existing another kind of active component such as active component Avermectin, emamectin-benzoate, beta-cypermethrin, phoxim etc. with microencapsulation form, and diafenthiuron is suspended form, thereby reduced harmful effect between two kinds of active components, and ultraviolet ray etc. is to the harmful effect of product, the better synergistic function between the performance Recompounded pesticide reaches stable storage, lasting medicine, bioavailability is high, control efficiency is good purpose.In addition, by above-mentioned each component content is cooperated selection, to bring into play separately effect and best composite effect.The average grain diameter of the particulate in the diafenthiuron suspension is the 0.5-10 micron, and preferred average grain diameter is the 1-5 micron.Therefore, in a preferred embodiment, the average grain diameter of the particulate in the average grain diameter of the second active component microcapsules and the diafenthiuron suspension is close, for example all is the 1-5 micron, thereby so that both are evenly distributed, form comparatively uniformly organic system that is mixed in final pesticidal preparations.Average grain diameter with the particulate in microcapsules average grain diameter and the diafenthiuron suspension in the present embodiment is preferably the 1-5 micron, the physical stability that stores to improve preparation.
The agricultural chemicals microcapsule suspension that contains diafenthiuron of present embodiment-suspending agent preparation method comprises the steps:
S01: make the second active component microcapsules by the second active component, cyst material and auxiliary agent;
S02: the former medicine of diafenthiuron is fully mixed, disperses with first's auxiliary agent and water, sand milling again, obtain diafenthiuron suspension, in described suspension, add the second active component microcapsules and the second portion auxiliary agent that makes, mix and disperse, obtain containing the agricultural chemicals microcapsule suspension-suspending agent of diafenthiuron, wherein adopt each component and the content of above-mentioned weight percentage meter in each step.
Various materials among step S01 and the S02 adopt above-described, no longer are repeated in this description at this.
The second active component microcapsule preparation method of step S01, can adopt chemical method such as interfacial polymerization, situ aggregation method preparation, also can be employing physico-chemical process such as compound curdled milk method, the preparation of complex phase emulsion method, perhaps be in physical method such as air suspension, jet drying method and the solvent evaporated method any one., described the second active component is Avermectin, emamectin-benzoate, gamma cyhalothrin, betacyfluthrin, beta-cypermethrin, sumicidin, chlopyrifos, malathion, phoxim or Hostathion.Cyst material among the step S01 comprises oiliness cyst material and/or water-soluble cyst material, can adopt oiliness, any cyst material in water-soluble, adopt water-soluble cyst material a kind of such as embodiment 2-5, and other embodiment adopt two kinds, make respectively not homophase, certainly also can adopt the oiliness cyst material a kind of.
Particularly, to adopt two microcapsule wall material aqua as example, the second active component microcapsule preparation method specifically comprises following process: the second active component, oiliness cyst material and emulsifier are dissolved in are prepared into oil phase in the solvent, dispersant, defoamer is as the auxiliary agent water that is prepared into soluble in water, then mixed with water with oil phase, form the O/W emulsion, add water-soluble cyst material and catalyzer, be warming up to 50 ℃～70 ℃, insulation reaction 2-6 hour, obtain described the second active component microcapsules.Particularly, shearing dispersion is under 2000-15000 rev/min, shears and disperses 1-10 minute.O/W emulsion preparation be that the average grain diameter of the second active component microcapsules is the microcapsule suspensions of 0.1-20 micron (preferred 1-5 micron), the average grain diameter 0.5-10 micron of sand milling suspended particulates in the described diafenthiuron suspension (preferred 1-5 micron).Catalyzer can be one or more the catalyst combination in hydrochloric acid, ammonium chloride or sodium hydroxide, the potassium hydroxide.By above-mentioned steps, the average grain diameter that obtains the second active component microcapsules is the 1-5 micron.
Among the step S02, auxiliary agent divides two parts to add, and first's auxiliary agent comprises wetting agent, dispersant, defoamer, and the second portion auxiliary agent comprises antifreeze, pH value conditioning agent, thickener and mould inhibitor.Because the former medicine of diafenthiuron is powdery, uses first wetting agent wetting, adds dispersant, defoamer and water again and fully mixes, and passes into the sand mill sand milling after being uniformly dispersed, sand milling to average grain diameter is the 1-5 micron, obtains diafenthiuron suspension; Then in suspension, add the second active component microcapsules and the second portion auxiliary agent that makes, mixing is uniformly dispersed, obtain containing the agricultural chemicals microcapsule suspension-suspending agent of diafenthiuron, wherein adopt each component and the content of above-mentioned weight percentage meter among step S01 and the S02.
By above-mentioned preparation process as can be known, present embodiment adopts the microencapsulation technology that the second active component is existed with microencapsulation form, especially to the light activated active component of ultraviolet, kind described above for example, can effectively reduce by two kinds of harmful effects between the active component like this, and ultraviolet ray or other light are to the harmful effect of product, thereby so that the product stable storage of preparation, lasting medicine, bioavailability is high and then reduced the medication number of times, has reduced cost accounting.In addition, above-mentioned preparation method is easy and simple to handle, and cost is low.
Below illustrate the preparation method of the agricultural chemicals microcapsule suspension-suspending agent that contains diafenthiuron by a plurality of embodiment, with and the aspects such as effect and performance, can be drawn composition and the content thereof of the microcapsule suspension-suspending agent that makes by preparation process.
The preparation of embodiment 1:32.5% diafenthiuron betacyfluthrin microcapsule suspension-suspending agent
The preparation of (1) 10% betacyfluthrin microcapsules
Betacyfluthrin (mass concentration 97.2%) 103 gram is dissolved among the 397 gram solvent S-200, adds 20 gram aliphatic polymeric isocyanates and 3 gram farming breasts 2201 and stir and form the O/W emulsion; 25 gram NNO (di-2-ethylhexylphosphine oxide bitter edible plant sodium sulfonate), 1 gram silicone defoaming agent are dissolved in the 445 gram water (formation water), add again the microcapsules oil phase, formed the O/W emulsion of average grain diameter 1-5 μ m in 1 minute at 15000 rev/mins of down cuts, add 6 gram ethylenediamines, be warming up to 70 ℃ of insulation reaction and namely got 10% betacyfluthrin microcapsules, 1000 grams in 4 hours.
The preparation of (2) 32.5% diafenthiuron betacyfluthrin microcapsule suspension-suspending agents
With the former medicine of diafenthiuron (mass concentration 98%) 305 gram, wetting agent (
4894) 30 the gram, dispersant (
2500) 40 grams, 2 gram silicone defoaming agents fully mix with 200 gram water, disperse, pass into the sand mill sand milling after being uniformly dispersed, sand milling is to average grain diameter 1-5 micron, and then the 10% betacyfluthrin microcapsules 250 that add step (1) preparation restrain, ethylene glycol (antifreezing agent) 40 grams, glacial acetic acid (pH adjusting agent) 30 grams, Sodium Benzoate (mould inhibitor) 10 grams, 1.5% xanthans colloidal solution (thickener), 67 grams and water 26 grams fully mix, and dispersed with stirring evenly is the present invention's 32.5% diafenthiuron betacyfluthrin microcapsule suspension-suspending agent.
Embodiment 2-embodiment 20: contain the preparation of the agricultural chemicals microcapsule suspension-suspending agent of diafenthiuron
The preparation of (1) second active component microcapsules
Step (1) among the step (1) of embodiment 2-embodiment 20 and the embodiment 1 is basic identical, difference be from embodiment 1 in step (1) in component different, specifically such as table 1.According to the composition in the table 1 and content, the second active component, oiliness cyst material and emulsifying dispersant be dissolved in the corresponding solvent be prepared into oil phase, with dispersant, the defoamer water that is prepared into soluble in water, then oil phase is mixed with water evenly, formed the O/W emulsion of average grain diameter 1-5 micron at 2000-15000 rev/min of down cut 1-10 minute, add water-soluble cyst material and suitable catalyzer, be warming up to 50 ℃～70 ℃, namely got the second active component microcapsules in insulation reaction 2-6 hour.
(2) contain the preparation of the agricultural chemicals microcapsule suspension-suspending agent of diafenthiuron
Step (2) among the step (2) of embodiment 2-embodiment 20 and the embodiment 1 is basic identical, difference be from embodiment 1 in step (2) in component different, specifically such as table 2.According to the composition in the table 2 and content, the former medicine of diafenthiuron, wetting agent, dispersant, defoamer and water are fully mixed, disperse, pass into the sand mill sand milling after being uniformly dispersed, sand milling to average grain diameter 1-5 micron namely gets diafenthiuron suspension, and then adding step (1) makes the second active component microcapsules, antifreeze, pH value conditioning agent, thickener, mould inhibitor, water supplies 100%, and fully mix and blend is uniformly dispersed and is the agricultural chemicals microcapsule suspension-suspending agent that contains diafenthiuron.
Compare with regular dosage form, the microcapsule suspension-suspending agent that contains diafenthiuron among the above embodiment has good storage-stable, and table 3 is preserved 7d, 14d test result at 0 ℃ ± 2 ℃ and 54 ℃ ± 2 ℃ respectively for above embodiment prepares sample.
Microcapsule suspension-suspending agent below in conjunction with containing diafenthiuron in the field medicine effect test explanation embodiment of the invention illustrates that it has concurrently quick-acting and slow releasing function, can improve the bioavailability of product, reduces the medication number of times, reduces cost accounting.
1. diamond-back moth field medicine effect test
Choose the consistent Chinese cabbage of growing way field, contain the phase even spraying age at diamond-back moth 1-2, test medicine is the microcapsule suspension-suspending agent that contains diafenthiuron of above-described embodiment and the regular dosage form product of identical active component and content thereof, the clear water contrast.Observed in 3 days, 7 days, 14 days and 28 days after dispenser, the control efficiency statistical conditions see Table 4.As seen from table, the drug effect of the medicament of every kind of microcapsule suspension-suspending agent after 28 days is at least more than 60%, major part is significantly higher than the regular dosage form product all more than 70%, illustrates that the medicament lasting effect of present embodiment microcapsule suspension-suspending agent is significantly better than aqueous suspension agent.
Table 4 contains the microcapsule suspension-suspending agent of diafenthiuron to the land for growing field crops drug effect of diamond-back moth
2. citrus red mite field medicine effect test
Choose the consistent citrus orchard of growing way, contain two spotted spider mite and send out the phase even spraying, test medicine is that the present invention contains the microcapsule suspension-suspending agent of diafenthiuron and the regular dosage form product of identical active component and content thereof, the clear water contrast.Observed in 3 days, 7 days, 14 days and 28 days after dispenser, the control efficiency statistics sees Table 5.Result in the table 5 is similar to table 4, shows equally embodiment of the invention microcapsule suspension-suspending agent and has fabulous lasting effect.
Table 5 contains the microcapsule suspension-suspending agent of diafenthiuron to the land for growing field crops drug effect of citrus red mite
The above only is preferred embodiment of the present invention, not in order to limiting the present invention, all any modifications of doing within the spirit and principles in the present invention, is equal to and replaces and improvement etc., all should be included within protection scope of the present invention.
Claims (10)
1. agricultural chemicals microcapsule suspension-suspending agent that contains diafenthiuron, it is comprised of the first active component diafenthiuron, the second active component microcapsules, auxiliary agent and water, and the weight percentage of each component is:
Described the second active component microcapsules are the microcapsules that contain the second active component.
2. the agricultural chemicals microcapsule suspension-suspending agent that contains diafenthiuron as claimed in claim 1, it is characterized in that described the second active component is Avermectin, emamectin-benzoate, gamma cyhalothrin, betacyfluthrin, beta-cypermethrin, sumicidin, chlopyrifos, malathion, phoxim or Hostathion.
3. the agricultural chemicals microcapsule suspension-suspending agent that contains diafenthiuron as claimed in claim 2, it is characterized in that, described the second active component is for having one of pesticide activity component of following weight percentage in microcapsules: Avermectin 0.5%～15%, emamectin-benzoate 0.5%～10%, gamma cyhalothrin 2.5%～25%, betacyfluthrin 2.5%～10%, beta-cypermethrin 2.5%～16%, sumicidin 2.5%～30%, chlopyrifos 15%～40%, malathion 15%～40%, phoxim 15%～40%, Hostathion 15%～40%.
4. the agricultural chemicals microcapsule suspension-suspending agent that contains diafenthiuron as claimed in claim 1 is characterized in that, described auxiliary agent is any combination of wetting agent, dispersant, thickener, antifreezing agent, mould inhibitor, defoamer or pH value conditioning agent.
5. the agricultural chemicals microcapsule suspension-suspending agent that contains diafenthiuron as claimed in claim 1, it is characterized in that, the average grain diameter of described the second active component microcapsules is the 1-5 micron, and described diafenthiuron exists with the suspended particulates form, and the suspended particulates average grain diameter of described diafenthiuron is the 1-5 micron.
6. the agricultural chemicals microcapsule suspension-suspending agent that contains diafenthiuron as claimed in claim 1, it is characterized in that, described the second active component microcapsules comprise the component of following percentage by weight: the second active component 0.5%～40%, solvent 2.5%～25%, oiliness cyst material 0.5%～4%, water-soluble cyst material 0.5%～70%, emulsifier 0.1%～1% and microcapsules auxiliary agent 0.5%～4%, above content is with the microcapsules calculation of total.
7. preparation method who contains the agricultural chemicals microcapsule suspension-suspending agent of diafenthiuron, it comprises the steps:
Make the second active component microcapsules by the second active component, cyst material and microcapsules auxiliary agent;
The former medicine of diafenthiuron is fully mixed, disperses with first's auxiliary agent and water, sand milling again, obtain diafenthiuron suspension, in described suspension, add the second active component microcapsules and the second portion auxiliary agent that makes, mix and disperse, obtain containing the agricultural chemicals microcapsule suspension-suspending agent of diafenthiuron, wherein adopt each component and content such as each described weight percentage meter of claim 1-6 in each step.
8. the agricultural chemicals microcapsule suspension that contains diafenthiuron as claimed in claim 7-suspending agent preparation method, it is characterized in that, making of described the second active component microcapsules comprises following process: with the second active component, oiliness cyst material and emulsifier are dissolved in and are prepared into oil phase in the solvent, with dispersant, defoamer is as the auxiliary agent water that is prepared into soluble in water, then oil phase is mixed with water, under 2000-15000 rev/min, shear and disperseed 1-10 minute, form the O/W emulsion, add water-soluble cyst material and catalyzer, be warming up to 50 ℃～70 ℃, insulation reaction 2-6 hour, obtain described the second active component microcapsules.
9. the agricultural chemicals microcapsule suspension that contains diafenthiuron as claimed in claim 8-suspending agent preparation method, it is characterized in that, described oiliness cyst material is toluene di-isocyanate(TDI), 4, one or more the combination in vulcabond, 1,6 one six methylene phenylene diisocyanate, many methylenes benzene polyisocyanates or aliphatic diisocyanate, aliphatic triisocyanate, the aliphatic polymeric isocyanate of washing of 4-diphenylmethyl; Described water-soluble cyst material is one or more the combination in ethylenediamine, propane diamine, diethylene glycol, diethylenetriamine, triethanolamine or urea resin prepolymer, the melamine resin prepolymer; Described catalyzer is one or more the combination in hydrochloric acid, ammonium chloride or sodium hydroxide, the potassium hydroxide.
10. the agricultural chemicals microcapsule suspension that contains diafenthiuron as claimed in claim 8-suspending agent preparation method, it is characterized in that, the preparation of described O/W emulsion be that the average grain diameter of the second active component microcapsules is the microcapsule suspensions of 1-5 micron, the average grain diameter 1-5 micron of sand milling suspended particulates in the described diafenthiuron suspension.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201110286577XA CN103004825A (en) | 2011-09-23 | 2011-09-23 | Microcapsule suspension-suspending agent containing diafenthiuron and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201110286577XA CN103004825A (en) | 2011-09-23 | 2011-09-23 | Microcapsule suspension-suspending agent containing diafenthiuron and preparation method thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN103004825A true CN103004825A (en) | 2013-04-03 |
Family
ID=47954356
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201110286577XA Pending CN103004825A (en) | 2011-09-23 | 2011-09-23 | Microcapsule suspension-suspending agent containing diafenthiuron and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN103004825A (en) |
Cited By (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103749526A (en) * | 2013-12-30 | 2014-04-30 | 青岛崂乡茶制品有限公司 | Insecticide for tea trees |
| CN103783036A (en) * | 2013-11-20 | 2014-05-14 | 深圳诺普信农化股份有限公司 | Insecticide water suspension agent containing pyriproxyfen microcapsule and preparation method thereof |
| CN103947640A (en) * | 2014-05-28 | 2014-07-30 | 陕西上格之路生物科学有限公司 | Bactericidal composition for controlling soil-borne diseases of crops |
| CN104522015A (en) * | 2015-01-22 | 2015-04-22 | 苏州佳辉化工有限公司 | Compound insecticide containing emamectin benzoate and diafenthiuron |
| CN104996429A (en) * | 2015-07-25 | 2015-10-28 | 山东农业大学 | Bactericidal composition for preventing and controlling potato black scurf |
| CN105145622A (en) * | 2015-09-25 | 2015-12-16 | 山东潍坊润丰化工股份有限公司 | Glyphosate salt and 2,4-D ester weeding composition and mixing method and application thereof |
| CN106689188A (en) * | 2016-11-24 | 2017-05-24 | 安徽省农业科学院植物保护与农产品质量安全研究所 | Pesticide composition, and micro-capsule suspended seed coating agent and preparation method thereof |
| CN107279150A (en) * | 2017-05-26 | 2017-10-24 | 北京明德立达农业科技有限公司 | A kind of microcapsule suspension suspending agent of containing chlorantraniliprole and AVM and preparation method thereof |
| CN111226923A (en) * | 2020-03-09 | 2020-06-05 | 上海生农生化制品股份有限公司 | Pyraclostrobin-oxine-copper microcapsule suspension-suspending agent and preparation method thereof |
| CN112449572A (en) * | 2018-06-18 | 2021-03-05 | Upl有限公司 | Stable co-formulations of benzoylureas and pyrethroids |
Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1557161A (en) * | 2004-01-14 | 2004-12-29 | 深圳市诺普信农化有限公司 | Insecticide and acaricide composition containing dingminiao, fenpropathrin and beta-cypermethrin |
| CN1792157A (en) * | 2005-12-30 | 2006-06-28 | 山东农业大学 | High performance cypermethrin micro-capsule emulsion |
| CN101554173A (en) * | 2008-04-11 | 2009-10-14 | 北京绿色农华生物工程技术有限公司 | Microemulsion containing diafenthiuron and high-efficiency cyhalothrin and method for preparing same |
| CN101642099A (en) * | 2009-08-31 | 2010-02-10 | 桂林集琦生化有限公司 | Pesticide suspension concentrate with organosilicon surfactant and preparation method thereof |
| CN101919386A (en) * | 2010-08-17 | 2010-12-22 | 陕西上格之路生物科学有限公司 | Insecticidal composition containing methoxyfenozide and synthetic pyrethroid insecticide |
| CN102037977A (en) * | 2011-01-18 | 2011-05-04 | 陕西上格之路生物科学有限公司 | Insecticidal composition containing thiacloprid amide and synthetic pyrethroid insecticide |
-
2011
- 2011-09-23 CN CN201110286577XA patent/CN103004825A/en active Pending
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1557161A (en) * | 2004-01-14 | 2004-12-29 | 深圳市诺普信农化有限公司 | Insecticide and acaricide composition containing dingminiao, fenpropathrin and beta-cypermethrin |
| CN1792157A (en) * | 2005-12-30 | 2006-06-28 | 山东农业大学 | High performance cypermethrin micro-capsule emulsion |
| CN101554173A (en) * | 2008-04-11 | 2009-10-14 | 北京绿色农华生物工程技术有限公司 | Microemulsion containing diafenthiuron and high-efficiency cyhalothrin and method for preparing same |
| CN101642099A (en) * | 2009-08-31 | 2010-02-10 | 桂林集琦生化有限公司 | Pesticide suspension concentrate with organosilicon surfactant and preparation method thereof |
| CN101919386A (en) * | 2010-08-17 | 2010-12-22 | 陕西上格之路生物科学有限公司 | Insecticidal composition containing methoxyfenozide and synthetic pyrethroid insecticide |
| CN102037977A (en) * | 2011-01-18 | 2011-05-04 | 陕西上格之路生物科学有限公司 | Insecticidal composition containing thiacloprid amide and synthetic pyrethroid insecticide |
Cited By (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103783036B (en) * | 2013-11-20 | 2016-01-06 | 深圳诺普信农化股份有限公司 | Insecticide aqueous suspension agent containing Nylar microcapsules and preparation method thereof |
| CN103783036A (en) * | 2013-11-20 | 2014-05-14 | 深圳诺普信农化股份有限公司 | Insecticide water suspension agent containing pyriproxyfen microcapsule and preparation method thereof |
| CN103749526A (en) * | 2013-12-30 | 2014-04-30 | 青岛崂乡茶制品有限公司 | Insecticide for tea trees |
| CN103947640A (en) * | 2014-05-28 | 2014-07-30 | 陕西上格之路生物科学有限公司 | Bactericidal composition for controlling soil-borne diseases of crops |
| CN103947640B (en) * | 2014-05-28 | 2016-08-24 | 陕西上格之路生物科学有限公司 | A kind of bactericidal composition preventing and treating crops soil-borne disease |
| CN104522015A (en) * | 2015-01-22 | 2015-04-22 | 苏州佳辉化工有限公司 | Compound insecticide containing emamectin benzoate and diafenthiuron |
| CN104996429A (en) * | 2015-07-25 | 2015-10-28 | 山东农业大学 | Bactericidal composition for preventing and controlling potato black scurf |
| CN105145622A (en) * | 2015-09-25 | 2015-12-16 | 山东潍坊润丰化工股份有限公司 | Glyphosate salt and 2,4-D ester weeding composition and mixing method and application thereof |
| CN105145622B (en) * | 2015-09-25 | 2017-07-28 | 山东潍坊润丰化工股份有限公司 | The Herbicidal combinations and its compounding method and application of a kind of glyphosate salt and 2,4 D esters |
| CN106689188A (en) * | 2016-11-24 | 2017-05-24 | 安徽省农业科学院植物保护与农产品质量安全研究所 | Pesticide composition, and micro-capsule suspended seed coating agent and preparation method thereof |
| CN106689188B (en) * | 2016-11-24 | 2019-11-01 | 安徽省农业科学院植物保护与农产品质量安全研究所 | Composition pesticide, microcapsule suspension seed-coating agent and preparation method thereof |
| CN107279150A (en) * | 2017-05-26 | 2017-10-24 | 北京明德立达农业科技有限公司 | A kind of microcapsule suspension suspending agent of containing chlorantraniliprole and AVM and preparation method thereof |
| CN112449572A (en) * | 2018-06-18 | 2021-03-05 | Upl有限公司 | Stable co-formulations of benzoylureas and pyrethroids |
| CN111226923A (en) * | 2020-03-09 | 2020-06-05 | 上海生农生化制品股份有限公司 | Pyraclostrobin-oxine-copper microcapsule suspension-suspending agent and preparation method thereof |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN103004825A (en) | Microcapsule suspension-suspending agent containing diafenthiuron and preparation method thereof | |
| CN103783036B (en) | Insecticide aqueous suspension agent containing Nylar microcapsules and preparation method thereof | |
| CN106259403B (en) | Plant growth regulator composition with synergistic effect | |
| CN106818734A (en) | Microcapsule formulation and its preparation, micro-capsule suspension | |
| CN102396508A (en) | Novel pesticide combination containing thiamethoxam | |
| CN102037977B (en) | Insecticidal composition containing thiacloprid amide and synthetic pyrethroid insecticide | |
| CN101919386B (en) | Insecticidal composition containing methoxyfenozide and synthetic pyrethroid insecticide | |
| CN103004867B (en) | Insecticidal composition with synergism | |
| CN102763664B (en) | Insecticide composite containing spirodiclofen and bifenazate | |
| CN102326579B (en) | Insecticidal composition containing cycloxaprid and synthetic pyrethroid insecticides | |
| CN104585224A (en) | Pesticide composition containing fluensulfone and pyrethroid insecticide | |
| CN101263819B (en) | Indoxacarb and chlorfluazuron insecticidal composition | |
| CN103518773B (en) | Insecticidal composition with synergism | |
| CN103004866B (en) | Insecticidal composition containing sufluoxime ether and pirimiphos-methyl | |
| CN103503896A (en) | Insecticide composition having synergistic effect | |
| CN102326583B (en) | Insecticidal composition containing epoxy insect pyridine and organic phosphorus insecticide | |
| CN105794811B (en) | A kind of Pesticidal combination and its method for controlling agricultural pests | |
| CN105794814B (en) | A kind of Pesticidal combination and its method for controlling agricultural pests | |
| CN102578114A (en) | Pesticide composite containing emamectin benzoate and tebufenozide | |
| CN103461372B (en) | A kind of agricultural insecticide composition containing imidaclothiz and ethyl pleocidin | |
| CN109832280A (en) | A kind of Pesticidal combination | |
| CN107691467A (en) | A kind of emamectin benzoate and efficient cypermethrin compounded agricultural chemical composition for disinsection and its preparation | |
| CN102047897A (en) | Pesticidal composition containing diafenthiuron | |
| CN101406187A (en) | Composition for killing insects and mites containing tetranoic acid and organophosphorus | |
| CN110731349A (en) | insecticide composition containing tebuconazole amide |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C12 | Rejection of a patent application after its publication | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20130403 |