CN108420829A - A kind of pet detumescence and promoting granulation cream - Google Patents

Abstract

The invention belongs to external-applied ointment technical fields, and in particular to a kind of pet detumescence and promoting granulation cream and preparation method thereof.The detumescence and promoting granulation cream is made of following raw material：10 15g of vaseline, 0.25 0.5g of erythromycin pulvis, 1% tincture of iodine, 5 8mL, 3 5g of white lime, 5 10g of borneol.This detumescence and promoting granulation cream is to mix borneol, erythromycin, white lime and 1% tincture of iodine according to a certain percentage, using vaseline as matrix, allowing borneol to give full play to, it relieves pain promoting muscle growth functions, white lime plays it and removes rotten astriction, the tincture of iodine and erythromycin inhibiting bacteria and diminishing inflammation, it is fabricated to a kind of ointment and is smeared for suppurative wound and used, each raw material cooperates, and synergistic function occurs.

Description

A kind of pet detumescence and promoting granulation cream

Technical field

The invention belongs to external-applied ointment technical fields, and in particular to a kind of pet detumescence and promoting granulation cream and preparation method thereof.

Background technology

The reasons such as there are many reason of causing pet wound, fight and bite between pet, and postoperative infection suppuration wound, sharp objects scratch Can cause pet suppurate creation at.Self nursing cognitive ability of dog, cat is poor, and wound is often by the serious scratching of pet itself It is licked with thermophilic, great influence can be caused to the everyway of the lives such as pet appetite, action by being not treated in time, the sense if large area is suppurated Dye wound is not treated in time, and can form bacteremia even septicemia, threat to life, therefore the drug that can have had is treated that have very much must It wants.

The document for curing animal injuries with externally used paste can now be found and there was only the flat autogamy wound of Zhang Wenjian, Su Qing 1 The injured horses for the treatment of, Song Yu and self-control traumatic treatment are stowed machine and wound the male mule of scapular region, and three people use camphor, big Yellow, white sugar is made " wound 1 " and smears big domestic animal wound according to a certain percentage, rarely has suppurative outer with externally used paste treatment pet The document of wound, and the patent of domestic related paste is also seldom.

Application No. is 201210271976.3 Chinese patent, to disclose a kind of sulfated compound for treating pet suppuration sore new Mycin composition and preparation method thereof, the composition are uniformly mixed by following components by the weight part ratio：Sulfuric acid is new 1~3 part of mycin, 3~5 parts of erythromycin thiocyanate, 1~2 part of lactic acid methoxybenzyl aminopyrimidine, cetab 1~3 Part, 3~5 parts of menthol, 50~70 parts of atoleine, 7~9 parts of glycerine, 0.4 part of ethylparaben, 1~3 part of essence, distilled water The compositions such as 80~113 parts.The beneficial effects of the invention are as follows：Reasonable recipe prepares simple, curative effect highly significant, clinical application card It is bright to have special efficacy to treatment pet suppuration sore.However component involved by the composition is more, and it is former to have violated antibacterials clinical application Then, i.e.,：With a kind of controllable infection of anti-infectious agent, it is not necessarily to drug combination.And body is easily to neomycin and sulfamido Synergist generates drug resistance, and neomycinsulphate is that aminoglycoside medicaments Poisoning is maximum in the patent, and trimethoprim (TMP) holds Easily cause young animal folic acid to absorb obstacle, uses with caution.

It discloses application No. is 201310316508.8 Chinese patent and a kind for the treatment of Hard agglut wound, various wounds and change The compound medicine of purulence disease.Mainly it is made of ascorbic acid, riboflavin, dragon's blood, stone honey, erythromycin, pseudo-ginseng, borneol.Mainly It is removed for wound sterilization, disinfection and the pollutant to various wounds such as abscess, ulcer, knife wounds, it can effective accelerating wound healing. However such as dragon's blood of the component involved by the compound medicine, it is expensive；Ascorbic acid is undetermined to the effect of skin ulcer, and anti-bad Hematic acid is acidic drug, should not can influence mutual drug effect, ascorbic acid is with erythromycin in clinic with alkaline drug riboflavin compatibility There are apparent incompatibility for intravenous administration, though the patent is topical agent, the drug of incompatibility also needs to use with caution.

Invention content

In view of the above-mentioned deficiencies in the prior art, it is an object of the present invention to provide a kind of pet detumescence and promoting granulation cream and its preparation side Method.This detumescence and promoting granulation cream is to mix borneol, erythromycin, white lime and 1% tincture of iodine according to a certain percentage, using vaseline as Matrix allows borneol to give full play to it and relieve pain promoting muscle growth functions, white lime and plays that it removes rotten astriction, the tincture of iodine and erythromycin is antibacterial disappears Inflammation, is fabricated to a kind of ointment and is smeared for suppurative wound and use, and each raw material cooperates, and synergistic function occurs.

To achieve the purpose of the present invention, it adopts the following technical scheme that：

A kind of pet detumescence and promoting granulation cream, is made of following raw material：Vaseline 10-15g, erythromycin pulvis 0.25g-0.5g（Phase When in 250,000-50 ten thousand units）, 1% tincture of iodine 5-8mL, white lime 3-5g, borneol 5-10g.

A method of pet as described above detumescence and promoting granulation cream is prepared, is included the following steps：

（1）White lime is spare in being ground into powdery in mortar；

（2）The borneol shape that is crushed into powder is spare；

（3）Vaseline is taken to be placed in clean container, by the white lime powder got ready, borneol powder and erythromycin pulvis, 1% iodine Tincture is added in vaseline, after fully stirring evenly, is packed into spare in air-tight bottle.

This detumescence and promoting granulation paste formulation is reasonable, and matrix of the vaseline as Chinese medicine ointment, chemical property is more stable, and nothing is matched 5 taboos, the release property of contained drug, penetrability are ideal, and nonirritant, anaphylaxis prepares the simple for process of ointment, easily In operation.

White lime can constipation, hemostasis, convergence the effects that going corruption, relieving pain bactericidal antiphlogistic, economy is convenient.

Iodine has powerful bactericidal effect, no matter to fungi, protozoon, or all effective, the local use to virus, bacterial spore Effect directly, it is reliable, the tincture of iodine as it is a kind of not only effectively, but also economic and widely used drug, when it directly acts on lesion, Micro alcohol volatilizees immediately, and iodide ion is calm and is permeated to hypothallus, and mycelia is destroyed rapidly, and lesion is gradually reduced, necrosis Tissue loss, collagenous fibres increase numerous reparation, make its scarring or restore certain transparency.

Erythromycin category macrolide antibiotics has stronger antibacterial activity, to certain gram-negatives to gram-positive bacteria Property bacterium and conveyor screw, mycoplasma pneumoniae, rickettsia and Chlamydia etc. also have an inhibiting effect, be especially used for staphylococcus or The disease of streptococcal infection, effect are especially good.

Borneol is to commonly use adjutant in traditional Chinese medicine simply, and Chinese medicine thinks that it has the benefits of inducing resuscitation of having one's ideas straightened out, clearing away heat to and alleviating pain, myogenic；It is existing Think that borneol has anti-inflammatory and antalgic, antibacterial, antiviral, protection heart and brain, bidirectional modulation nervous system, raising other drugs life for medicine The effects that object utilizes, and analgesic effect becomes apparent than anti-inflammatory effect；Borneol can promote drug through membranes barriers to reach Optimal absorption of the drug in body, distribution, can reduce other drugs dosage in clinical application, increase drug effect, Reduce drug toxicity, side effect；Borneol is bitter, is slightly cold, is cool in nature, just applies from ancient times and treats disease in drug matching, especially to gold The bacteriums such as staphylococcus aureus have stronger bacteriostasis, and most strong with the antibacterial activity of finish.《Amplification on Materia Medica》Think its work It is " then gesture of walking alone is weak, and assistant makes then active " with feature.

The beneficial effects of the present invention are：

This detumescence and promoting granulation cream is to mix borneol, erythromycin, white lime and 1% tincture of iodine according to a certain percentage, using vaseline as Matrix allows borneol to give full play to it and relieve pain promoting muscle growth functions, white lime and plays that it removes rotten astriction, the tincture of iodine and erythromycin is antibacterial disappears Inflammation, is fabricated to a kind of ointment and is smeared for suppurative wound and use.The detumescence and promoting granulation cream drug prescription is simple, convenient material drawing, respectively Drug price is cheap, can be preserved under normal temperature environment after the making of this paste is complete, clinical application effect indifference meets China beast Cure clinical application criterion.

Description of the drawings

Fig. 1 is operation wound clearing, before smearing detumescence and promoting granulation cream prepared by embodiment 2；

Fig. 2 is to smear detumescence and promoting granulation cream 5 day after tomorrow of design sketch；

Fig. 3 is to smear detumescence and promoting granulation cream 9 day after tomorrow of design sketch；

Fig. 4 is that healing completely is schemed after smearing detumescence and promoting granulation cream day 15.

Specific implementation mode

Further to disclose rather than the present invention is limited, the present invention is described in further detail below in conjunction with example.

Embodiment 1

A kind of pet detumescence and promoting granulation cream, is made of following raw material：Vaseline 10g, erythromycin pulvis 0.5g, 1% tincture of iodine 5mL are ripe Lime 5g, borneol 5g.

The production method of this externally used paste is：

（1）White lime is spare in being ground into powdery in mortar；

（2）The borneol shape that is crushed into powder is spare；

（3）Vaseline is taken to be placed in clean container, by the white lime powder got ready, borneol powder and erythromycin pulvis, 1% iodine Tincture is added in vaseline, after fully stirring evenly, is packed into spare in air-tight bottle.

Embodiment 2

A kind of pet detumescence and promoting granulation cream, is made of following raw material：Vaseline 12g, erythromycin pulvis 0.35g, 1% tincture of iodine 6mL, White lime 4g, borneol 8g.

The production method of this externally used paste is：

（1）White lime is spare in being ground into powdery in mortar；

（2）The borneol shape that is crushed into powder is spare；

（3）Vaseline is taken to be placed in clean container, by the white lime powder got ready, borneol powder and erythromycin pulvis, 1% iodine Tincture is added in vaseline, after fully stirring evenly, is packed into spare in air-tight bottle.

Embodiment 3

A kind of pet detumescence and promoting granulation cream, is made of following raw material：Vaseline 15g, erythromycin pulvis 0.25g, 1% tincture of iodine 8mL, White lime 3g, borneol 10g.

The production method of this externally used paste is：

（1）White lime is spare in being ground into powdery in mortar；

（2）The borneol shape that is crushed into powder is spare；

（3）Vaseline is taken to be placed in clean container, by the white lime powder got ready, borneol powder and erythromycin pulvis, 1% iodine Tincture is added in vaseline, after fully stirring evenly, is packed into spare in air-tight bottle.

Inventive formulation embodiment is enumerated below：

Sanming City, Fujian Province Meilie District Melbourne pet clinic 100 many cases wound of detumescence and promoting granulation cream pair made from embodiment 2 is changed Purulence wound etc. suffers from dog, cat has been cooked clinical observation on the therapeutic effect, all achieves good curative effect.

Now an example typicalness case is described below：

Suffer from cat Anna, 3 years old, female, in May, 2018 day raw kitten, after four cubs are given birth in natural labor, because being nursed to female cat and right The nursing of cub is looked after not enough, and female cat breast gland milk is caused to lump, mammary gland inflammation swelling, final mother's cat breast gland product milk part large area It bursts, right side breast two is to the equal ulceration in milk head（Such as Fig. 1）.Therapy：

After carrying out blood biochemical and blood routine examination, anesthesia, pars affecta skin shaving, the thorough cleaning surface of a wound use suppuration necrotic area Operating scissors coordinate blade scraping totally to expose to the fresh surface of a wound, because ulceration region is very big, can not use suture, rinse well Afterwards, detumescence and promoting granulation cream thickness about 1-2mm is uniformly smeared in all surface of a wound.It wears Elizabethan's circle and prevents from suffering from cat licking to suffer from cat and lick wound Mouthful, the promise of antiphlogistic speed is subcutaneously injected and Ke Te is strengthened continuous five days, and wound site is cleared up every 3 days, smears detumescence life Flesh cream, large area heals the surface of a wound after dressing four times（Such as Fig. 2, Fig. 3, Fig. 4）.

The foregoing is merely presently preferred embodiments of the present invention, all equivalent changes done according to scope of the present invention patent with Modification should all belong to the covering scope of the present invention.

Claims (2)

1. a kind of pet detumescence and promoting granulation cream, it is characterised in that：It is made of following raw material：Vaseline 10-15g, erythromycin pulvis 0.25-0.5g, 1% tincture of iodine 5-8mL, white lime 3-5g, borneol 5-10g.

2. a kind of method preparing pet as described in claim 1 detumescence and promoting granulation cream, it is characterised in that：Including following step Suddenly：

（1）White lime is spare in being ground into powdery in mortar；

（2）The borneol shape that is crushed into powder is spare；

（3）Vaseline is taken to be placed in clean container, by the white lime powder got ready, borneol powder and erythromycin pulvis, 1% iodine Tincture is added in vaseline, after fully stirring evenly, is packed into spare in air-tight bottle.