CN108403500A - A kind of refrigerant anti-pruritic compositions - Google Patents

A kind of refrigerant anti-pruritic compositions Download PDF

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CN108403500A
CN108403500A CN201810359345.4A CN201810359345A CN108403500A CN 108403500 A CN108403500 A CN 108403500A CN 201810359345 A CN201810359345 A CN 201810359345A CN 108403500 A CN108403500 A CN 108403500A
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extract
composition
volatile oil
refrigerant
glabrous sarcandra
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不公告发明人
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Foshan Harvest Chemical Technology Co Ltd
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Foshan Harvest Chemical Technology Co Ltd
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/61—Myrtaceae (Myrtle family), e.g. teatree or eucalyptus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783—Angiosperms [Magnoliophyta]
    • A61K8/9789—Magnoliopsida [dicotyledons]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/04—Antipruritics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/005—Antimicrobial preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/59—Mixtures
    • A61K2800/592—Mixtures of compounds complementing their respective functions
    • A61K2800/5922—At least two compounds being classified in the same subclass of A61K8/18

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  • Alternative & Traditional Medicine (AREA)
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  • Oil, Petroleum & Natural Gas (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Cosmetics (AREA)

Abstract

The invention discloses a kind of refrigerant anti-pruritic compositions, include the ingredient of following mass percent：Glabrous sarcandra herb extract 0.4 10%, Beggarticks extract 0.2 8%, Swamp Mahogany Leaf volatile oil 0.1 4%.The present composition effectively plays antibacterial anti-inflammatory, clearing heat and cooling blood, repairs the effect of antipruritic, realizes the refrigerant antipruritic purpose of skin, and skin is enabled to restore and maintain health status.

Description

A kind of refrigerant anti-pruritic compositions
Technical field
The present invention relates to cosmetic fields, and in particular to a kind of refrigerant anti-pruritic compositions.
Background technology
Along with people's sebaceous glands, sweat gland atrophy, the grease and sweat of secretion are reduced, movement is also reduced.Which reduces Protective effect to skin, make dry skin, drying skin inherently by the skin of countless fine injuries, this injury Performance is exactly itch on the skin.The blood circulation of peripheral vessel is bad, and the capillary in skin often has metabolin that cannot arrange Go out, stimulates the sensory nerve on skin, cause itch.External used medicine, with the sebaceous glands of alkaline strong soap and patient skin Cause dry skin etc. that can cause pruitus with sweat gland secretion hypofunction.
Invention content
The technical problem to be solved in the present invention is to provide a kind of refrigerant anti-pruritic compositions.The present composition effectively plays anti- Bacterium anti-inflammatory, repairs the effect of antipruritic at clearing heat and cooling blood, realizes the refrigerant antipruritic purpose of skin, and skin is enabled to restore and maintain healthy shape State.
To achieve the above object, the present invention provides following scheme：
A kind of refrigerant anti-pruritic compositions, include the ingredient of following mass percent：Glabrous sarcandra herb extract 0.4-10%, Bidens bipinnata Careless extract 0.2-8%, Swamp Mahogany Leaf volatile oil 0.1-4%.
Further, the composition includes the ingredient of following mass percent：Glabrous sarcandra herb extract 0.8-9%, ghost Needle grass extract 0.5-7%, Swamp Mahogany Leaf volatile oil 0.2-3.8%.
Further, the composition includes the ingredient of following mass percent：Glabrous sarcandra herb extract 4.5%, ghost Needle grass extract 3.5%, Swamp Mahogany Leaf volatile oil 2%.
A kind of refrigerant anti-pruritic compositions, the preparation method of the glabrous sarcandra herb extract are：Glabrous Sarcandra Herb is cleaned into drying, is crushed 20-40 mesh sieve is crossed, according to solid-liquid ratio 1:50-70% ethyl alcohol, heating and refluxing extraction 3 times at 60-80 DEG C, each 1- is added in 5-15 2h, filtering concentrate after merging extracting solution through Rotary Evaporators, vacuum drying.
A kind of refrigerant anti-pruritic compositions, the preparation method of the Beggarticks extract are：By beggar-ticks clean dry, crush 20-40 mesh sieve is crossed, according to solid-liquid ratio 1:5-15 addition 70-95% ethyl alcohol, refluxing extraction 3 times at 50-70 DEG C, each 1-2h, Merging filtrate after filtering, filtrate are concentrated under reduced pressure through Rotary Evaporators, then in 60 DEG C of vacuum drying.
The preparation method of a kind of refrigerant anti-pruritic compositions, the Swamp Mahogany Leaf volatile oil is：Eucalyptus robusta blade is cut into 1- 3cm2Fragment, be placed in volatile oil extractor and connect the conventional steam way of distillation and continuously extract 5-7h, collected grease is suspended Liquid is extracted with ether, and gained volatile oil is dehydrated with anhydrous sodium sulfate after low temperature recycling ether, is preserved at 4 DEG C.
Composition provided by the invention can be used for the preparation of cosmetics, wherein the composition can be used as additive and be used for The preparation of refrigerant antipruritic essence dew.
A kind of refrigerant antipruritic essence dew, further includes the ingredient of following mass percent：Glycerine 3.0-5.0%, butanediol It is 1.0-3.0%, glycine betaine 1.0-3.0%, xanthans 0.05-0.1%, glucan 2.0-5.0%, trehalose 1.0-3.0%, sweet Oxalic acid dipotassium 0.01-0.05%, Sodium Hyaluronate 0.01-0.03%, carbomer 0.1-0.2%, triethanolamine 0.01- 0.03%, Sensiva SC50 0.1-0.5%, Phenoxyethanol 0.1-0.5%, EDTA-2 sodium 0.01-0.05%, double-PEG/ PPG-16/16PEG/PPG-16/16 dimethyl silicone polymers/caprylic/capric triglyceride 0.5-1.0%, PPG-26- butanol is poly- Ether -26/PEG-40 hydrogenated castor oil/waters 0.05-0.25%, dimethyl silicone polymer/Parleam 0.5-1.0%, ring Five dimethyl silicone polymer 1.0-3.0%, tocopherol acetate 0.05-0.2%, essence 0.05-0.08%, Rhodophyta algae (RHODOPHYTA) extract/brown alga extract/sorb (sugar) alcohol/water 0.1-0.5%, deionized water surplus.
Compared with prior art, the invention has the advantages that：
The present invention is by three kinds of glabrous sarcandra herb extract, Beggarticks extract and Swamp Mahogany Leaf volatile oil natural plant composition compoundings Composition, it is mildly non-stimulated to human skin, with antibacterial anti-inflammatory, clearing heat and cooling blood, antipruritic effect is repaired, skin is enabled to restore and tie up Hold health status.Glabrous sarcandra herb extract, Beggarticks extract, Swamp Mahogany Leaf volatile oil have the effect of clearing heat and cooling blood, enhance blood Liquid recycles, and boosts metabolism, and promotes the discharge of metabolin in capillary, effectively realizes refrigerant antipruritic effect.Glabrous Sarcandra Herb Extract, Beggarticks extract, Swamp Mahogany Leaf volatile oil have the effect of antibacterial, effectively inhibit skin surface bacterium, to rise To antipruritic effect.
Specific implementation mode
To make the object, technical solutions and advantages of the present invention clearer, embodiment of the present invention will be made into one below Step ground detailed description, embodiments of the present invention are not limited thereto, for not specifically specified technological parameter or condition, can refer to Routine techniques carries out.
Involved each ingredient is described as follows in composition of the present invention：
Glabrous Sarcandra Herb (also known as Chloranthus glaber, sarcandra, elder) is conventional Chinese medicine, is Chloranthaceae (chioranthaceae) The drying complete stool of Sarcandra plant Chloranthus glaber.Glabrous Sarcandra Herb bitter, pungent, mild-natured, tool clearing heat and cooling blood, ecchymose removing of invigorating blood circulation, dispelling wind and removing obstruction in the meridians And other effects, for treating the diseases such as blood-head purple plague purpura, purpura, arthralgia pain due to rheumatism, traumatic injury.Modern pharmacology and toxicological study show swollen section Wind have antibacterial anti-inflammatory, inhibit influenza virus, it is antitumor, promote the various actives such as union and analgesia, and Glabrous Sarcandra Herb and Its extract has preferable safety.
Beggar-ticks Bidens bipinnata L. also known as grass, a caecum grass etc., it is bitter in taste, flat, it is nontoxic, it is planted for composite family The herb of object beggar-ticks etc..In addition《Quanzhou book on Chinese herbal medicine》Also the record of " dispersing blood stasis, analgesia, hold back metal-inflicted wound " finds Bidens bipinnata through modern study Grass contains alkaloid, and saponin, glycosides displayed, tannin, cauline leaf is containing volatile oil, tannin, choline etc..The ethanol extract of beggar-ticks is right in vitro Gram-positive bacterium has good bacteriostasis, has inhibiting effect to staphylococcus aureus and fungi, still there is anti-mistake in addition Quick effect has clearing heat and cooling blood, removing toxic substances, detumescence, dissipates the functions such as stasis of blood apocenosis, eliminating dampness is antipruritic.
Swamp Mahogany Leaf is the leaf of dicotyledon Myrtaceae eucalyptus robusta (Eucalyptus robusta Smith), taste It is pungent, bitter, it is cool in nature, have dispelling wind deliver, be clearing heat and detoxicating, expelling phlegm and arresting coughing, antipruritic desinsection the effect of.Great Ye is by being that South China is civil Common Chinese herbal medicine, leaf water decoction have the antipruritic effect of clearing heat and detoxicating, anti-inflammatory analgetic, anti-corrosion, and total volatile oil can be used for treating The diseases such as influenza, the infection of the upper respiratory tract and skin disease.It is reported according to documents and materials, eucalyptus oil has antipyretic anti-inflammatory and resists Bacterium corrosion-resistant acts on.
Embodiment 1
A kind of refrigerant antipruritic essence dew, includes the ingredient of following mass percent：Glabrous sarcandra herb extract 0.8%, beggar-ticks Extract 0.5%, Swamp Mahogany Leaf volatile oil 0.2%, glycerine 3.5%, butanediol 1.5%, glycine betaine 1.5%, xanthans 0.06%, glucan 3%, trehalose 1.5%, dipotassium glycyrrhizinate 0.02%, Sodium Hyaluronate 0.01%, carbomer 0.1%, three Ethanol amine 0.01%, Sensiva SC50 0.2%, Phenoxyethanol 0.2%, EDTA-2 sodium 0.02%, double-PEG/PPG-16/ 16PEG/PPG-16/16 dimethyl silicone polymers/caprylic/capric triglyceride 0.6%, PPG-26- butylol polyethers -26/PEG- 40 hydrogenated castor oil/waters 0.1%, dimethyl silicone polymer/Parleam 0.7%, ring five dimethyl silicone polymer 1.5%, tocopherol acetate 0.1%, essence 0.06%, Rhodophyta algae (RHODOPHYTA) extract/brown alga extract/sorb (sugar) alcohol/water 0.2%, deionized water surplus.
Embodiment 2
A kind of refrigerant antipruritic essence dew, includes the ingredient of following mass percent：Glabrous sarcandra herb extract 9%, beggar-ticks carry Take object 7%, Swamp Mahogany Leaf volatile oil 3.8%, glycerine 4.5%, butanediol 2.5%, glycine betaine 2.5%, xanthans 0.08%, Portugal Glycan 4%, trehalose 2.5%, dipotassium glycyrrhizinate 0.04%, Sodium Hyaluronate 0.03%, carbomer 0.15%, triethanolamine 0.015%, Sensiva SC50 0.4%, Phenoxyethanol 0.4%, EDTA-2 sodium 0.04%, double-PEG/PPG-16/16PEG/ PPG-16/16 dimethyl silicone polymers/the caprylic/capric triglyceride 0.8%, -26/PEG-40 hydrogenations of PPG-26- butylol polyethers Castor-oil plant oil/water 0.2%, dimethyl silicone polymer/Parleam 0.8%, ring five dimethyl silicone polymer 2.5%, fertility Phenol acetic acid esters 0.15%, essence 0.07%, Rhodophyta algae (RHODOPHYTA) extract/brown alga extract/sorb (sugar) alcohol/water 0.4%, deionized water surplus.
Embodiment 3
A kind of refrigerant antipruritic essence dew, includes the ingredient of following mass percent：Glabrous sarcandra herb extract 4.5%, beggar-ticks Extract 3.5%, Swamp Mahogany Leaf volatile oil 2%, glycerine 4%, butanediol 2%, glycine betaine 2%, xanthans 0.06%, glucan 3.5%, trehalose 2%, dipotassium glycyrrhizinate 0.03%, Sodium Hyaluronate 0.02%, carbomer 0.15%, triethanolamine 0.02%, Sensiva SC50 0.3%, Phenoxyethanol 0.3%, EDTA-2 sodium 0.03%, double-PEG/PPG-16/16PEG/ PPG-16/16 dimethyl silicone polymers/the caprylic/capric triglyceride 0.7%, -26/PEG-40 hydrogenations of PPG-26- butylol polyethers Castor-oil plant oil/water 0.2%, dimethyl silicone polymer/Parleam 0.7%, ring five dimethyl silicone polymer 2%, tocopherol Acetic acid esters 0.15%, essence 0.06%, Rhodophyta algae (RHODOPHYTA) extract/brown alga extract/sorb (sugar) alcohol/water 0.3%, deionized water surplus.
Embodiment 4
A kind of refrigerant antipruritic essence dew, includes the ingredient of following mass percent：Glabrous sarcandra herb extract 0.4%, beggar-ticks Extract 0.2%, Swamp Mahogany Leaf volatile oil 0.1%, glycerine 3.0%, butanediol 1.0%, glycine betaine 1.0%, xanthans 0.05%, glucan 2.0%, trehalose 1.0%, dipotassium glycyrrhizinate 0.01%, Sodium Hyaluronate 0.01%, carbomer 0.1%, Triethanolamine 0.01%, Sensiva SC50 0.1%, Phenoxyethanol 0.1%, EDTA-2 sodium 0.01%, double-PEG/PPG-16/ 16PEG/PPG-16/16 dimethyl silicone polymers/caprylic/capric triglyceride 0.5%, PPG-26- butylol polyethers -26/PEG- 40 hydrogenated castor oil/waters 0.05%, dimethyl silicone polymer/Parleam 0.5%, ring five dimethyl silicone polymer 1.0%, tocopherol acetate 0.05%, essence 0.05%, Rhodophyta algae (RHODOPHYTA) extract/brown alga extract/mountain Pears (sugar) alcohol/water 0.1%, deionized water surplus.
Embodiment 5
A kind of refrigerant antipruritic essence dew, includes the ingredient of following mass percent：Glabrous sarcandra herb extract 10%, beggar-ticks carry Take object 8%, Swamp Mahogany Leaf volatile oil 4%, glycerine 5.0%, butanediol 3.0%, glycine betaine 3.0%, xanthans 0.1%, Portugal poly- Sugar 5.0%, trehalose 3.0%, dipotassium glycyrrhizinate 0.05%, Sodium Hyaluronate 0.03%, carbomer 0.2%, triethanolamine 0.03%, Sensiva SC50 0.5%, Phenoxyethanol 0.5%, EDTA-2 sodium 0.05%, double-PEG/PPG-16/16PEG/ PPG-16/16 dimethyl silicone polymers/the caprylic/capric triglyceride 1.0%, -26/PEG-40 hydrogenations of PPG-26- butylol polyethers Castor-oil plant oil/water 0.25%, dimethyl silicone polymer/Parleam 1.0%, ring five dimethyl silicone polymer 3.0%, fertility Phenol acetic acid esters 0.2%, essence 0.08%, Rhodophyta algae (RHODOPHYTA) extract/brown alga extract/sorb (sugar) alcohol/water 0.5%, deionized water surplus.
A kind of preparation method of refrigerant antipruritic essence dew is in embodiment 1-5：(1) by above-mentioned composition, double-PEG/PPG- 16/16PEG/PPG-16/16 dimethyl silicone polymers/caprylic/capric triglyceride, PPG-26- butylol polyethers -26/PEG-40 Hydrogenated castor oil/water, dimethyl silicone polymer/Parleam, ring five dimethyl silicone polymer, tocopherol acetate mixing It stirs evenly, A phases is made；(2) by glycerine, butanediol, glycine betaine, xanthans, glucan, trehalose, dipotassium glycyrrhizinate, transparent Obtained B phases are mixed evenly in matter acid sodium, carbomer, EDTA-2 sodium, deionized water；(3) A is added to B phases, emulsifying homogeneous C phases are made in 3min；(4) by triethanolamine, essence, Rhodophyta algae (RHODOPHYTA) extract/brown alga extract/sorb (sugar) alcohol/water, Sensiva SC50, the stirring of Phenoxyethanol side sequentially add C phases, stir evenly, discharge.
Comparative example 1
Difference lies in glabrous sarcandra herb extract is not added with embodiment 1.
Comparative example 2
Difference lies in Beggarticks extract is not added with embodiment 1.
Comparative example 3
Difference lies in Swamp Mahogany Leaf volatile oil is not added with embodiment 1.
Comparative example 4
Difference lies in glabrous sarcandra herb extract, Beggarticks extract, Swamp Mahogany Leaf volatile oil are not added with embodiment 1.
Efficacy validation
Human body patch test
Organize 50 volunteers according to《Cosmetics safety technical specification》The human skin patch of (2015 editions) records, The back of subject will be pasted on low sensitization adhesive tape added with the spot of tested material examination device or forearm song is surveyed, gently pressed with palm and be allowed to equal It is pasted on skin, continues for 24 hours evenly.Test the refrigerant antipruritic essence of one kind obtained by 1-5 of the embodiment of the present invention and comparative example 1-4 Hua Lu is to the potential adverse reaction of human skin, and the results are shown in Table 1.
Table 1
A kind of refrigerant antipruritic essence dew made from embodiment 1-5 is nonirritant to human skin as can be seen from Table 1.
Efficacy validation
600 volunteers are selected, per each 50 triers of test group.It is prepared using embodiment 1-5, comparative example 1-4 clear Cool antipruritic essence dew, participant respectively use 1 time, persistently use 1 month sooner or later daily.It must not be used in experimentation other any Skin-protection product, and subject has been fully completed verification process, and experimental result is shown in Table 2, and effect divides three grades：
Refrigerant antipruritic effect is apparent：Refrigerant antipruritic effect is apparent, and antipruritic, refrigerant skin of releiving is with obvious effects；
Refrigerant antipruritic effect is general：Refrigerant antipruritic effect is general, when use a little refrigerant sense；
Refrigerant antipruritic effect unobvious：For pruitus without improvement, dry skin is matt, dry skin, itch situation with Difference is little before, feels without apparent after.
2 each embodiment of table, comparative example using effect
The refrigerant antipruritic essence dew pair that the embodiment of the present invention is provided is can be seen that from the result of the self-assessment of trier Most trier's skin have the effect of preferable refrigerant antipruritic, the refrigerant antipruritic purpose of realization.
The present invention is described by way of example above, but the present invention is not limited to above-mentioned specific embodiment, all to be based on Any changes or modifications that the present invention is done belong to the scope of protection of present invention.

Claims (9)

1. a kind of refrigerant anti-pruritic compositions, which is characterized in that include the ingredient of following mass percent：Glabrous sarcandra herb extract 0.4- 10%, Beggarticks extract 0.2-8%, Swamp Mahogany Leaf volatile oil 0.1-4%.
2. composition as described in claim 1, which is characterized in that include the ingredient of following mass percent：Glabrous Sarcandra Herb extracts Object 0.8-9%, Beggarticks extract 0.5-7%, Swamp Mahogany Leaf volatile oil 0.2-3.8%.
3. composition as claimed in claim 2, which is characterized in that include the ingredient of following mass percent：Glabrous Sarcandra Herb extracts Object 4.5%, Beggarticks extract 3.5%, Swamp Mahogany Leaf volatile oil 2%.
4. composition as described in any one of claims 1-3, which is characterized in that the preparation method of the glabrous sarcandra herb extract For：Glabrous Sarcandra Herb is cleaned into drying, 20-40 mesh sieve is crushed, according to solid-liquid ratio 1:50-70% ethyl alcohol is added in 5-15, in 60-80 DEG C Lower heating and refluxing extraction 3 times, each 1-2h, filtering concentrate after merging extracting solution through Rotary Evaporators, vacuum drying.
5. composition as described in any one of claims 1-3, which is characterized in that the preparation method of the Beggarticks extract For：By beggar-ticks clean dry, 20-40 mesh sieve is crushed, according to solid-liquid ratio 1:70-95% ethyl alcohol is added in 5-15, in 50-70 DEG C Lower refluxing extraction 3 times, each 1-2h, merging filtrate after filtering, filtrate is concentrated under reduced pressure through Rotary Evaporators, then in 60 DEG C of vacuum Drying.
6. composition as described in any one of claims 1-3, which is characterized in that the preparation method of the Swamp Mahogany Leaf volatile oil For：Eucalyptus robusta blade is cut into 1-3cm2Fragment, be placed in volatile oil extractor and connect the conventional steam way of distillation and continuously extract 5-7h, collected grease suspension are extracted with ether, and gained volatile oil is dehydrated with anhydrous sodium sulfate after low temperature recycling ether, in It is preserved at 4 DEG C.
7. composition as claimed in any one of claims 1 to 6, which is characterized in that the composition can be used for the system of cosmetics It is standby.
8. composition as claimed in claim 7, which is characterized in that the composition can be used as additive for refrigerant antipruritic essence The preparation of Hua Lu.
9. a kind of refrigerant antipruritic essence dew, which is characterized in that further include the ingredient of following mass percent：Glycerine 3.0-5.0%, Butanediol 1.0-3.0%, glycine betaine 1.0-3.0%, xanthans 0.05-0.1%, glucan 2.0-5.0%, trehalose 1.0- 3.0%, dipotassium glycyrrhizinate 0.01-0.05%, Sodium Hyaluronate 0.01-0.03%, carbomer 0.1-0.2%, triethanolamine 0.01-0.03%, Sensiva SC50 0.1-0.5%, Phenoxyethanol 0.1-0.5%, EDTA-2 sodium 0.01-0.05%, it is double- PEG/PPG-16/16 PEG/PPG-16/16 dimethyl silicone polymers/caprylic/capric triglyceride 0.5-1.0%, PPG-26- Butylol polyether -26/PEG-40 hydrogenated castor oil/waters 0.05-0.25%, dimethyl silicone polymer/Parleam 0.5- 1.0%, ring five dimethyl silicone polymer 1.0-3.0%, tocopherol acetate 0.05-0.2%, essence 0.05-0.08%, red algae Door algae (RHODOPHYTA) extract/brown alga extract/sorb (sugar) alcohol/water 0.1-0.5%, deionized water surplus.
CN201810359345.4A 2018-04-20 2018-04-20 A kind of refrigerant anti-pruritic compositions Withdrawn CN108403500A (en)

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110227109A (en) * 2019-06-26 2019-09-13 高宗旺 A kind of composition and preparation method thereof for pig chronic eczema
CN111821231A (en) * 2020-06-19 2020-10-27 广州艾蓓生物科技有限公司 Refreshing composition and preparation method thereof
CN113712867A (en) * 2021-09-13 2021-11-30 吴囡 Antioxidant discoloration plant type essence composition and preparation method and application thereof

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110227109A (en) * 2019-06-26 2019-09-13 高宗旺 A kind of composition and preparation method thereof for pig chronic eczema
CN110227109B (en) * 2019-06-26 2021-09-17 高宗旺 Composition for chronic eczema of pigs and preparation method thereof
CN111821231A (en) * 2020-06-19 2020-10-27 广州艾蓓生物科技有限公司 Refreshing composition and preparation method thereof
CN113712867A (en) * 2021-09-13 2021-11-30 吴囡 Antioxidant discoloration plant type essence composition and preparation method and application thereof

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Application publication date: 20180817