CN108619017A - A kind of Tianshan Mountains snow chrysanthemum skin care compositions and its application - Google Patents
A kind of Tianshan Mountains snow chrysanthemum skin care compositions and its application Download PDFInfo
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
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Abstract
The invention discloses a kind of Tianshan Mountains snow chrysanthemum skin care compositions, are prepared by the Tibetan medicine of following parts by weight：1 10 parts of Tibetan Codonopsis, 1 10 parts of Gymnadenia conopsea, 1 10 parts of Tianshan Mountains snow chrysanthemum, 1 10 parts of flax, 1 10 parts of garden sorrel.For the Tianshan Mountains snow chrysanthemum skin care compositions of the present invention according to assistant and guide formula principle, monarch drug in a prescription is Tibetan Codonopsis, Gymnadenia conopsea, and ministerial drug is Tianshan Mountains snow chrysanthemum, and adjutant is flax, and it is garden sorrel to make medicine, is cooperated, collective effect.Have the effects that heat-clearing, moisturizes, wind-dispelling, clearing damp, detumescence, promote dermal fibroblasts synthesis collagen, remove free radical.Tianshan Mountains snow chrysanthemum skin care compositions, which is applied, to be had the function of antipyretic and itching-stopping in the skin-protection products such as skin cream, promote skin elasticity, improvement or eliminates fash and eczema, can be promoted wound healing, be repaired and be damaged skin, smooth microgroove.
Description
Technical field
The present invention relates to cosmetic fields, and in particular to a kind of Tianshan Mountains snow chrysanthemum skin care compositions and its application.
Background technology
Qinghai-Tibet Platean special geographical location, ecological environment and weather conditions create kind uniqueness and abundant dynamic plant
Goods and materials source.Tibet black fungus, ganoderma lucidum, Rhizoma Gastrodiae have unique physicochemical property and drug action, and the mankind, which but lack Tibetan medicine material, is
The further investigation of system.The Tibetan medicine places of origin of raw materials is backward in economy, has inconvenient traffic, and lacks the support of advanced technology, so Tibetan medicine material is more
It is for sale in the form of raw material, the economic benefit of bigger can not be created.How the research and development of Tibetan medicine material are conformed to the principle of simplicity
Single direct roughing is converted to finishing, improves its quality and drug effect；How on the basis of prior art high-tech is largely introduced
Skill technology, exploitation novel form, new product are current most urgent problems to be solved to adapt to the clinical and market demand.
Invention content
The technical problem to be solved in the present invention is to provide a kind of Tianshan Mountains snow chrysanthemum skin care compositions and its applications.
The specific technical solution for solving above-mentioned technical problem is as follows：
A kind of Tianshan Mountains snow chrysanthemum skin care compositions, is prepared by the Tibetan medicine of following parts by weight：1-10 parts of Tibetan Codonopsis, fingered citron
1-10 parts of ginseng, snow chrysanthemum 1-10 parts of Tianshan Mountains, 1-10 parts of flax, 1-10 parts of garden sorrel.
Further, the Tianshan Mountains snow chrysanthemum skin care compositions is prepared by the Tibetan medicine of following parts by weight：Tibetan Codonopsis 3-7
Part, 2-6 parts of Gymnadenia conopsea, snow chrysanthemum 4-8 parts of Tianshan Mountains, 5-8 parts of flax, 3-6 parts of garden sorrel.
Further, the preparation method of the Tianshan Mountains snow chrysanthemum skin care compositions is as follows：(1) it decocts：Weigh Tibetan Codonopsis,
Gymnadenia conopsea, Tianshan Mountains snow chrysanthemum, flax, garden sorrel mixing, dry, pulverize, and mixing medicinal material is placed in iron pot, deionized water is added not have
Cross drug, it is soaking, heat, boil to water and be all evaporated, medicine is cooked, boils soft, obtains and decocts mixing medicinal material；(2) it sends out
Ferment：Mixing medicinal material will be decocted to take out, 35-45 DEG C is cooled to, root enzyme bacterium is added, stirs evenly, seal；In 10-20 DEG C of condition
Lower fermentation 5-10 days obtains fermentation medicinal material；
(3) it extracts：Fermentation medicinal material is placed in iron pot, is added in the ethyl alcohol that volume fraction is 50-95%, uses
The ultrasonication that frequency is 25kHZ-45kHZ 1-10 minutes, then water-bath flows back 1-2 hours under conditions of 90-100 DEG C,
100-500 mesh filter-cloth filterings collect filtrate and filter residue respectively；Filter residue is repeated into extraction 1 time with above-mentioned extracting method again, by two
Filtrate obtained by secondary extraction merges；Obtain first extract；(4) it filters：First extract is centrifuged, supernatant liquor is taken, in 2-5 DEG C of low temperature item
It is preserved 1-2 days under part, then with aperture 1-2 microns of filter plant pressure filtration, is restored to room temperature to get Tianshan Mountains snow chrysanthemum skin care
Composition.
Further, the grain size crushed in the step (1) is 10-100 mesh.
Further, in the step (2), the additive amount of the root enzyme bacterium is the 0.01- for decocting mixing medicinal material weight
0.1%.The present invention using root enzyme bacterium ferment, remain Tibetan Codonopsis, Gymnadenia conopsea, Tianshan Mountains snow chrysanthemum, flax, garden sorrel functional component and
Activity, active constituent caused by avoiding during the fermentation are lost in.Skin can effectively be enhanced to feeling caused by bacterium, fungi
The immunity of dye can make skin become to lubricate, and moisture is sufficient, high resilience.
Further, in the step (3), the weight ratio of the fermentation medicinal material and ethyl alcohol is 1:(3-7).
The present invention also provides application of the Tianshan Mountains snow chrysanthemum skin care compositions in preparing cosmetics, wherein the day
Mountain snow chrysanthemum skin care compositions dosage be final products weight 0.1-10wt%.
A kind of skin cream includes the component of following mass percentage：Above-mentioned Tianshan Mountains snow chrysanthemum skin care compositions 0.1-
10%, dormant oil 15-35%, dimethyl silicone polymer 1-5%, diethyl hexylcarbonate 1-10%, cetostearyl alcohol olive oleic acid
- 30 1-3%, PEG/PPG-4/12 dimethyl silicone polymer 0.5-5% of ester polyether, cetostearyl alcohol olive oleate 1-5%,
Cocoyl-glucoside citrate disodium 0.1-3%, -100 0.5-2% of stereth, wheat germ oil hydrogenation 0.1-
5%, Parleam 0.1-5%, PEG-7 caprylic/caprics glyceride type 0.1-1%, stearyl alcohol 0.1-3%, bee saage
(HYPTIS SUAVEOLENS) seed oil 0.1-3%, acrylamide/sodium Acrylate copolymer 0.1-0.6%, glycine betaine 0.1-
5%, polyalcohol 5-20%, protease glucan 0.1-3%, water surplus.
Further, the polyalcohol is at least one of sorbierite, glycerine, 1,3 butanediols.
The present invention has the advantages that：
For the Tianshan Mountains snow chrysanthemum skin care compositions of the present invention according to assistant and guide formula principle, monarch drug in a prescription is Tibetan Codonopsis, fingered citron
Ginseng, ministerial drug are Tianshan Mountains snow chrysanthemum, and adjutant is flax, and it is garden sorrel to make medicine, is cooperated, collective effect.With heat-clearing, moisturizes, dispels
Wind, detumescence, promotes dermal fibroblasts synthesis collagen, removes the effects that free radical clearing damp.By Tianshan Mountains snow chrysanthemum skin care group
Closing object and applying has antipyretic and itching-stopping in the skin-protection products such as skin cream, promotes skin elasticity, improvement or eliminates fash and eczema
Effect, can promote wound healing, repair and be damaged skin, smooth microgroove.
Snow chrysanthemum skin care compositions preparation process combining with fermentation in Tianshan Mountains of the present invention and ultrasonic extraction are greatly improved and hide party
Ginseng, Gymnadenia conopsea, Tianshan Mountains snow chrysanthemum, flax, garden sorrel yield of active ingredients.
Specific implementation mode
To make the object, technical solutions and advantages of the present invention clearer, embodiment of the present invention will be made into one below
Step ground detailed description, embodiments of the present invention are not limited thereto, for not specifically specified technological parameter or condition, can join
More solito technology carries out.
Tibetan Codonopsis is the herb of Campanulaceae length flower Radix Codonopsis Codonopsis mollis Chipp..With dry yellow water,
The effect of detumescence.For rheumatic arthritis, boil pain is swollen, leprosy.Originate from China's southern Tibet and middle part.Sillim and Buddhist nun
Bo Er etc. is also distributed.It is born in mountainous region grass slope and the shrubbery of 3600-4600 meters of height above sea level.
The Tibetan medicine of Gymnadenia conopsea is entitled " prosperous drawing ", orchid family herbaceos perennial, due to originating in sacred Buddhist site and likeness in form palm
It gains the name.Gymnadenia conopsea is born in snowy region on 3500 meters of Qinghai-Tibet Platean for many years, shows preciousness since growth period is long, is referred to as in Tibetan medicine
For magical " not old grass ".《Compendium of Materia Medica》It is middle claim its can " yang-tonifying the deficiency of blood fire, establishing-Yang controlling nocturnal emission with astringent drugs, salubrity benefit marrow " top grade.Through existing
It is proved for scientific research：It is rich in a variety of saponin(es and eugenol in Gymnadenia conopsea, all has stronger anti-oxidant and delaying human body and declines
The effect of old, particularly human body brain tissue and skin aging.Scientific research also confirms：Polysaccharide is rich in conic gymnadenia tuber.Wherein β-egg
White enzyme glucan also has good Transdermal absorption performance in addition to anti-ageing because of its straight-chain molecular structure, can promote skin, special
Be not skin depth hand skin in fibrocyte synthesis collagen, promote wound healing, repair and be damaged skin, smooth thin
Line, improve moistened as elasticity of skin and more aobvious silk it is smooth.
Tianshan Mountains snow chrysanthemum is to hydroxy radical (OH), Superoxide anion free radical (O2-) and 1,1- diphenyl -2- trinitrobenzens
The scavenging effect that hydrazine (DPPH) free radical has had.When the mass concentration of 50% ethyl alcohol coreopsis tinctoria extract is 1.0g/L,
The clearance rate of OH, O2- and DPPH free radical is respectively 86%, 97% and 71%, and Scavenging activity is suitable with VC, is had good
Antioxidation.
Flax is the dry mature seed of flax family (Linaceae) plant flax Linum usitatissimum L..With moisturizing, dispel
The effect of wind.For dry constipation of intestines, itch is had dry skin, hair is withered to fall off.
Garden sorrel is the dry root of polygonaceae plant Nepal garden sorrel Rumex nepalensis Spreng.With heat-clearing, dispel
It is wet, detumescence, more sore the effect of.For boil, eczema.
Embodiment 1
A kind of skin cream includes the component of following mass percentage：Tianshan Mountains snow chrysanthemum skin care compositions 0.1%, dormant oil
15%, dimethyl silicone polymer 1%, diethyl hexylcarbonate 10%, cetostearyl alcohol olive oleate polyethers -30 3%,
PEG/PPG-4/12 dimethyl silicone polymers 0.5%, cetostearyl alcohol olive oleate 1%, cocoyl-glucoside citric acid
Ester disodium 3%, stereth -100 2%, wheat germ oil hydrogenation 0.1%, Parleam 5%, PEG-7 octanoic acids/
Glycerol decanoate class 0.1%, stearyl alcohol 3%, bee saage (HYPTIS SUAVEOLENS) seed oil 0.1%, acrylamide/acrylic acid
Sodium copolymer 0.6%, glycine betaine 0.1%, sorbierite 5%, protease glucan 3%, water surplus.
The Tianshan Mountains snow chrysanthemum skin care compositions is prepared by the Tibetan medicine of following parts by weight：10 parts of Tibetan Codonopsis, Gymnadenia conopsea 1
Part, 10 parts of Tianshan Mountains snow chrysanthemum, 1 part of flax, 10 parts of garden sorrel.
The preparation method of the Tianshan Mountains snow chrysanthemum skin care compositions is as follows：(1) it decocts：Weigh Tibetan Codonopsis, Gymnadenia conopsea, day
Mountain snow chrysanthemum, flax, garden sorrel mixing, dry, pulverize to 100 mesh, and mixing medicinal material is placed in iron pot, deionized water is added not have
Drug, it is soaking, heat, boil to water and be all evaporated, medicine is cooked, boils soft, obtains and decocts mixing medicinal material；(2) it ferments：
Mixing medicinal material will be decocted to take out, be cooled to 45 DEG C, root enzyme bacterium is added, the additive amount of the root enzyme bacterium is to decoct mixing medicinal material
The 0.01% of weight, stirs evenly, sealing；It ferments 10 days under the conditions of 10 DEG C, obtains fermentation medicinal material；(3) it extracts：It will fermentation
Medicinal material is placed in iron pot, is added in the ethyl alcohol that volume fraction is 50%, and the weight ratio of the fermentation medicinal material and ethyl alcohol is
1:7；Use frequency for the ultrasonication 10 minutes of 25kHZ, then water-bath flows back 2 hours under conditions of 100 DEG C, the filter of 100 mesh
Cloth filters, and collects filtrate and filter residue respectively；Filter residue is repeated into extraction 1 time with above-mentioned extracting method again, gained filter will be extracted twice
Liquid merges；Obtain first extract；(4) it filters：First extract is centrifuged, supernatant liquor is taken, is preserved 2 days under 5 DEG C of cryogenic conditions, then
With 2 microns of the filter plant pressure filtration in aperture, room temperature is restored to get Tianshan Mountains snow chrysanthemum skin care compositions.
Embodiment 2
A kind of skin cream includes the component of following mass percentage：Tianshan Mountains snow chrysanthemum skin care compositions 10%, dormant oil
35%, dimethyl silicone polymer 5%, diethyl hexylcarbonate 1%, cetostearyl alcohol olive oleate polyethers -30 1%,
PEG/PPG-4/12 dimethyl silicone polymers 5%, cetostearyl alcohol olive oleate 5%, cocoyl-glucoside citrate
Disodium 0.1%, stereth -100 0.5%, wheat germ oil hydrogenation 5%, Parleam 0.1%, PEG-7 are pungent
Acid/glycerol decanoate class 1%, stearyl alcohol 0.1%, bee saage (HYPTIS SUAVEOLENS) seed oil 3%, acrylamide/propylene
Sour sodium copolymer 0.1%, glycine betaine 5%, glycerine 20%, protease glucan 0.1%, water surplus.
The Tianshan Mountains snow chrysanthemum skin care compositions is prepared by the Tibetan medicine of following parts by weight：1 part of Tibetan Codonopsis, Gymnadenia conopsea 10
Part, 1 part of Tianshan Mountains snow chrysanthemum, 10 parts of flax, 1 part of garden sorrel.
The preparation method of the Tianshan Mountains snow chrysanthemum skin care compositions is as follows：(1) it decocts：Weigh Tibetan Codonopsis, Gymnadenia conopsea, day
Mountain snow chrysanthemum, flax, garden sorrel mixing, dry, pulverize to 10 mesh, and mixing medicinal material is placed in iron pot, deionized water is added not have medicine
Object, it is soaking, heat, boil to water and be all evaporated, medicine is cooked, boils soft, obtains and decocts mixing medicinal material；(2) it ferments：It will
It decocts mixing medicinal material to take out, is cooled to 35 DEG C, root enzyme bacterium is added, the additive amount of the root enzyme bacterium is to decoct mixing medicinal material weight
The 0.1% of amount, stirs evenly, and seals；It ferments 5 days under the conditions of 20 DEG C, obtains fermentation medicinal material；(3) it extracts：To ferment medicinal material
It is placed in iron pot, is added in the ethyl alcohol that volume fraction is 95%, the weight ratio of the fermentation medicinal material and ethyl alcohol is 1:3；
Use frequency for the ultrasonication 1 minute of 45kHZ, then water-bath flows back 1 hour under conditions of 90 DEG C, 500 mesh filter cloth mistakes
Filtrate and filter residue are collected in filter respectively；Filter residue is repeated into extraction 1 time with above-mentioned extracting method again, gained filtrate will be extracted twice and closed
And；Obtain first extract；(4) it filters：First extract is centrifuged, supernatant liquor is taken, is preserved 1 day under 2 DEG C of cryogenic conditions, then use hole
The filter plant pressure filtration of 1 micron of diameter is restored to room temperature to get Tianshan Mountains snow chrysanthemum skin care compositions.
Embodiment 3
A kind of skin cream includes the component of following mass percentage：Tianshan Mountains snow chrysanthemum skin care compositions 6%, dormant oil
25%, dimethyl silicone polymer 3%, diethyl hexylcarbonate 5%, cetostearyl alcohol olive oleate polyethers -30 2%,
PEG/PPG-4/12 dimethyl silicone polymers 3%, cetostearyl alcohol olive oleate 3%, cocoyl-glucoside citrate
Disodium 1.5%, stereth -100 1%, wheat germ oil hydrogenation 2%, Parleam 3%, the PEG-7 octanoic acids/last of the ten Heavenly stems
Acid glycerol esters 0.5%, stearyl alcohol 1.5%, bee saage (HYPTIS SUAVEOLENS) seed oil 2%, acrylamide/sodium Acrylate
Copolymer 0.3%, glycine betaine 3%, sorbierite 15%, protease glucan 1.5%, water surplus.
The Tianshan Mountains snow chrysanthemum skin care compositions is prepared by the Tibetan medicine of following parts by weight：5 parts of Tibetan Codonopsis, Gymnadenia conopsea 4
Part, 6 parts of Tianshan Mountains snow chrysanthemum, 7 parts of flax, 4 parts of garden sorrel.
The preparation method of the Tianshan Mountains snow chrysanthemum skin care compositions is as follows：(1) it decocts：Weigh Tibetan Codonopsis, Gymnadenia conopsea, day
Mountain snow chrysanthemum, flax, garden sorrel mixing, dry, pulverize to 50 mesh, and mixing medicinal material is placed in iron pot, deionized water is added not have medicine
Object, it is soaking, heat, boil to water and be all evaporated, medicine is cooked, boils soft, obtains and decocts mixing medicinal material；(2) it ferments：It will
It decocts mixing medicinal material to take out, is cooled to 40 DEG C, root enzyme bacterium is added, the additive amount of the root enzyme bacterium is to decoct mixing medicinal material weight
The 0.05% of amount, stirs evenly, and seals；It ferments 8 days under the conditions of 15 DEG C, obtains fermentation medicinal material；(3) it extracts：To ferment medicinal material
It is placed in iron pot, is added in the ethyl alcohol that volume fraction is 70%, the weight ratio of the fermentation medicinal material and ethyl alcohol is 1:5；
Use frequency for the ultrasonication 5 minutes of 40kHZ, then water-bath flows back 2 hours under conditions of 95 DEG C, 300 mesh filter cloth mistakes
Filtrate and filter residue are collected in filter respectively；Filter residue is repeated into extraction 1 time with above-mentioned extracting method again, gained filtrate will be extracted twice and closed
And；Obtain first extract；(4) it filters：First extract is centrifuged, supernatant liquor is taken, is preserved 1 day under 4 DEG C of cryogenic conditions, then use hole
The filter plant pressure filtration of 2 microns of diameter is restored to room temperature to get Tianshan Mountains snow chrysanthemum skin care compositions.
Embodiment 4
A kind of skin cream includes the component of following mass percentage：Tianshan Mountains snow chrysanthemum skin care compositions 3%, dormant oil
20%, dimethyl silicone polymer 1-5%, diethyl hexylcarbonate 2%, cetostearyl alcohol olive oleate polyethers -30
1.5%, PEG/PPG-4/12 dimethyl silicone polymers 2.5%, cetostearyl alcohol olive oleate 2%, cocoyl-glucoside
Citrate disodium 0.5%, stereth -100 0.8%, wheat germ oil hydrogenation 4%, Parleam 2%,
PEG-7 caprylic/caprics glyceride type 0.8%, stearyl alcohol 1%, bee saage (HYPTIS SUAVEOLENS) seed oil 0.7%, propylene
Amide/sodium acrylate copolymer 0.5%, glycine betaine 4%, 1,3 butanediols 10%, protease glucan 1%, water surplus.
The Tianshan Mountains snow chrysanthemum skin care compositions is prepared by the Tibetan medicine of following parts by weight：7 parts of Tibetan Codonopsis, Gymnadenia conopsea 2
Part, 8 parts of Tianshan Mountains snow chrysanthemum, 5 parts of flax, 6 parts of garden sorrel.
The preparation method of the Tianshan Mountains snow chrysanthemum skin care compositions is as follows：(1) it decocts：Weigh Tibetan Codonopsis, Gymnadenia conopsea, day
Mountain snow chrysanthemum, flax, garden sorrel mixing, dry, pulverize to 80 mesh, and mixing medicinal material is placed in iron pot, deionized water is added not have medicine
Object, it is soaking, heat, boil to water and be all evaporated, medicine is cooked, boils soft, obtains and decocts mixing medicinal material；(2) it ferments：It will
It decocts mixing medicinal material to take out, is cooled to 35 DEG C, root enzyme bacterium is added, the additive amount of the root enzyme bacterium is to decoct mixing medicinal material weight
The 0.08% of amount, stirs evenly, and seals；It ferments 6 days under the conditions of 14 DEG C, obtains fermentation medicinal material；(3) it extracts：To ferment medicinal material
It is placed in iron pot, is added in the ethyl alcohol that volume fraction is 90%, the weight ratio of the fermentation medicinal material and ethyl alcohol is 1:4；
Use frequency for the ultrasonication 8 minutes of 30kHZ, then water-bath flows back 2 hours under conditions of 93 DEG C, 400 mesh filter cloth mistakes
Filtrate and filter residue are collected in filter respectively；Filter residue is repeated into extraction 1 time with above-mentioned extracting method again, gained filtrate will be extracted twice and closed
And；Obtain first extract；(4) it filters：First extract is centrifuged, supernatant liquor is taken, is preserved 1 day under 4 DEG C of cryogenic conditions, then use hole
The filter plant pressure filtration of 2 microns of diameter is restored to room temperature to get Tianshan Mountains snow chrysanthemum skin care compositions.
Embodiment 5
A kind of skin cream includes the component of following mass percentage：Tianshan Mountains snow chrysanthemum skin care compositions 8%, dormant oil
30%, dimethyl silicone polymer 1-5%, diethyl hexylcarbonate 7%, cetostearyl alcohol olive oleate polyethers -30
2.5%, PEG/PPG-4/12 dimethyl silicone polymers 2%, cetostearyl alcohol olive oleate 4%, cocoyl-glucoside lemon
Lemon acid esters disodium 2.5%, stereth -100 1.6%, wheat germ oil hydrogenation 2%, Parleam 4%, PEG-7
Caprylic/capric glyceride type 0.2%, stearyl alcohol 2%, bee saage (HYPTIS SUAVEOLENS) seed oil 2%, acrylamide/the third
Olefin(e) acid sodium copolymer 0.2%, glycine betaine 2%, glycerine 10%, 1,3 butanediols 5%, protease glucan 2.5%, water surplus.
The Tianshan Mountains snow chrysanthemum skin care compositions is prepared by the Tibetan medicine of following parts by weight：3 parts of Tibetan Codonopsis, Gymnadenia conopsea 6
Part, 4 parts of Tianshan Mountains snow chrysanthemum, 8 parts of flax, 3 parts of garden sorrel.
The preparation method of the Tianshan Mountains snow chrysanthemum skin care compositions is as follows：(1) it decocts：Weigh Tibetan Codonopsis, Gymnadenia conopsea, day
Mountain snow chrysanthemum, flax, garden sorrel mixing, dry, pulverize to 60 mesh, and mixing medicinal material is placed in iron pot, deionized water is added not have medicine
Object, it is soaking, heat, boil to water and be all evaporated, medicine is cooked, boils soft, obtains and decocts mixing medicinal material；(2) it ferments：It will
It decocts mixing medicinal material to take out, is cooled to 40 DEG C, root enzyme bacterium is added, the additive amount of the root enzyme bacterium is to decoct mixing medicinal material weight
The 0.03% of amount, stirs evenly, and seals；It ferments 9 days under the conditions of 18 DEG C, obtains fermentation medicinal material；(3) it extracts：To ferment medicinal material
It is placed in iron pot, is added in the ethyl alcohol that volume fraction is 80%, the weight ratio of the fermentation medicinal material and ethyl alcohol is 1:6；
Use frequency for the ultrasonication 3 minutes of 35kHZ, then water-bath flows back 1 hour under conditions of 97 DEG C, 200 mesh filter cloth mistakes
Filtrate and filter residue are collected in filter respectively；Filter residue is repeated into extraction 1 time with above-mentioned extracting method again, gained filtrate will be extracted twice and closed
And；Obtain first extract；(4) it filters：First extract is centrifuged, supernatant liquor is taken, is preserved 1 day under 3 DEG C of cryogenic conditions, then use hole
The filter plant pressure filtration of 2 microns of diameter is restored to room temperature to get Tianshan Mountains snow chrysanthemum skin care compositions.
Comparative example 1
The difference is that, comparative example 1 is not added with Tibetan Codonopsis with embodiment 3.
Comparative example 2
The difference is that, comparative example 2 is not added with Gymnadenia conopsea with embodiment 3.
Comparative example 3
The difference is that, comparative example 3 is not added with Tianshan Mountains snow chrysanthemum with embodiment 3.
Comparative example 4
The difference is that, comparative example 4 is not added with flax with embodiment 3.
Comparative example 5
The difference is that, comparative example 5 is not added with garden sorrel with embodiment 3.
Comparative example 6
With embodiment 3 the difference is that, 6 central Tianshan snow chrysanthemum skin care compositions of comparative example by following parts by weight Tibetan
Medicine is prepared：11 parts of Tibetan Codonopsis, 0.9 part of Gymnadenia conopsea, 11 parts of Tianshan Mountains snow chrysanthemum, 0.9 part of flax, 11 parts of garden sorrel.
Comparative example 7
With embodiment 3 the difference is that, 7 central Tianshan snow chrysanthemum skin care compositions of comparative example by following parts by weight Tibetan
Medicine is prepared：0.9 part of Tibetan Codonopsis, 11 parts of Gymnadenia conopsea, 0.9 part of Tianshan Mountains snow chrysanthemum, 11 parts of flax, 0.9 part of garden sorrel.
Skin cream made from above-described embodiment and comparative example continuously tries out 30 through the 100 of 20~50 years old personnel respectively
It, the effect of skin cream obtained in the various embodiments described above is evaluated in comparative analysis.Wherein, test event is skin elasticity, red
The improvement situation of spot, itch, fash, eczema etc., the results are shown in Table 1.
Table 1
The skin cream of above-described embodiment 1-5 and comparative example 1-7 do not find that irritation and allergy are existing during on probation
As.
As known from Table 1：Each product is bright to the improvement degree of skin elasticity, erythema, itch, fash, eczema etc. in embodiment
It is aobvious higher than the improvement degree of each product in comparative example；Show Tibetan Codonopsis, fingered citron in the Tianshan Mountains snow chrysanthemum skin care compositions of the present invention
The effect of ginseng, Tianshan Mountains snow chrysanthemum, flax, garden sorrel compound through specific prescription, be far longer than the simple before no prescription has association
With the effect of synergy.
The above described is only a preferred embodiment of the present invention, limitation in any form not is done to the present invention,
Therefore all contents without departing from technical solution of the present invention, according to the technical essence of the invention any letter made to the above embodiment
Single modification, equivalent variations and modification, in the range of still falling within technical solution of the present invention.
Claims (9)
1. a kind of Tianshan Mountains snow chrysanthemum skin care compositions, which is characterized in that be prepared by the Tibetan medicine of following parts by weight：Tibetan Codonopsis 1-10
Part, 1-10 parts of Gymnadenia conopsea, snow chrysanthemum 1-10 parts of Tianshan Mountains, 1-10 parts of flax, 1-10 parts of garden sorrel.
2. snow chrysanthemum skin care compositions in Tianshan Mountains according to claim 1, goes to be characterized in that, the Tianshan Mountains snow chrysanthemum skin care compositions
It is prepared by the Tibetan medicine of following parts by weight：3-7 parts of Tibetan Codonopsis, 2-6 parts of Gymnadenia conopsea, snow chrysanthemum 4-8 parts of Tianshan Mountains, 5-8 parts of flax, acid
3-6 parts of mould.
3. snow chrysanthemum skin care compositions in Tianshan Mountains according to claim 1 or 2, which is characterized in that the Tianshan Mountains snow chrysanthemum skin care
The preparation method of composition is as follows：(1) it decocts：Weigh Tibetan Codonopsis, Gymnadenia conopsea, Tianshan Mountains snow chrysanthemum, flax, garden sorrel mixing, dry, powder
It is broken, mixing medicinal material is placed in iron pot, deionized water is added not have a drug, it is soaking, heat, boil to water and be all evaporated,
Medicine is cooked, boils soft, acquisition decoction mixing medicinal material；(2) it ferments：Mixing medicinal material will be decocted to take out, 35-45 DEG C is cooled to, is added
Root enzyme bacterium, stirs evenly, sealing；It ferments 5-10 days under the conditions of 10-20 DEG C, obtains fermentation medicinal material；(3) it extracts：To ferment medicine
Material is placed in iron pot, is added in the ethyl alcohol that volume fraction is 50-95%, is used frequency for the ultrasonic wave of 25kHZ-45kHZ
Processing 1-10 minutes, then water-bath flows back 1-2 hours under conditions of 90-100 DEG C, 100-500 mesh filter-cloth filterings collect filter respectively
Liquid and filter residue；Filter residue is repeated into extraction 1 time with above-mentioned extracting method again, gained filtrate will be extracted twice and merged；Obtain first extract；
(4) it filters：First extract is centrifuged, supernatant liquor is taken, is preserved 1-2 days under 2-5 DEG C of cryogenic conditions, then with aperture 1-2 microns
Filter plant pressure filtration is restored to room temperature to get Tianshan Mountains snow chrysanthemum skin care compositions.
4. snow chrysanthemum skin care compositions in Tianshan Mountains according to claim 3, which is characterized in that the grain crushed in the step (1)
Diameter is 10-100 mesh.
5. snow chrysanthemum skin care compositions in Tianshan Mountains according to claim 3, which is characterized in that in the step (2), the root
The additive amount of enzyme bacterium is the 0.01-0.1% for decocting mixing medicinal material weight.
6. snow chrysanthemum skin care compositions in Tianshan Mountains according to claim 3, which is characterized in that in the step (3), the fermentation
The weight ratio of medicinal material and ethyl alcohol is 1:(3-7).
7. according to application of claim 1-6 any one of them Tianshan Mountains snow chrysanthemum skin care compositions in preparing cosmetics, wherein
The Tianshan Mountains snow chrysanthemum skin care compositions dosage be final products weight 0.1-10wt%.
8. a kind of skin cream, which is characterized in that include the component of following mass percentage：Such as any one of claim 1-6 institutes
Tianshan Mountains snow chrysanthemum skin care compositions 0.1-10%, dormant oil 15-35%, dimethyl silicone polymer 1-5%, the diethyl hexylcarbonate stated
1-10%, -30 1-3%, PEG/PPG-4/12 dimethyl silicone polymer 0.5-5% of cetostearyl alcohol olive oleate polyethers, whale
Wax stearyl alcohol olive oleate 1-5%, cocoyl-glucoside citrate disodium 0.1-3%, -100 0.5- of stereth
2%, wheat germ oil hydrogenation 0.1-5%, Parleam 0.1-5%, PEG-7 caprylic/capric glyceride type 0.1-1%,
Stearyl alcohol 0.1-3%, bee saage (HYPTIS SUAVEOLENS) seed oil 0.1-3%, acrylamide/sodium Acrylate copolymer 0.1-
0.6%, glycine betaine 0.1-5%, polyalcohol 5-20%, protease glucan 0.1-3%, water surplus.
9. skin cream according to claim 8, which is characterized in that the polyalcohol is sorbierite, glycerine, 1,3 butanediols
At least one of.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109512714A (en) * | 2019-01-15 | 2019-03-26 | 西藏大学 | A kind of book on Chinese herbal medicine UV white whitening toner and preparation method thereof |
| KR20210153045A (en) * | 2019-04-08 | 2021-12-16 | 상하이 호프-테크 바이오테크놀로지 아이엔씨 | Extraction method of palm orchid and related palm orchid extract |
-
2018
- 2018-05-12 CN CN201810455405.2A patent/CN108619017A/en not_active Withdrawn
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109512714A (en) * | 2019-01-15 | 2019-03-26 | 西藏大学 | A kind of book on Chinese herbal medicine UV white whitening toner and preparation method thereof |
| KR20210153045A (en) * | 2019-04-08 | 2021-12-16 | 상하이 호프-테크 바이오테크놀로지 아이엔씨 | Extraction method of palm orchid and related palm orchid extract |
| KR102623447B1 (en) * | 2019-04-08 | 2024-01-10 | 상하이 호프-테크 바이오테크놀로지 아이엔씨 | Extraction method of palm orchid and related palm orchid extract |
| US12048726B2 (en) | 2019-04-08 | 2024-07-30 | Shanghai Hope-Tec Biotechnology Inc. | Method for extracting Gymnadenia conopsea and related Gymnadenia conopsea extract |
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